SIMILAR PATTERNS OF AMINO ACIDS FOR 4C8B_B_0LIB1000_1

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1h4l	CELL DIVISION PROTEIN KINASE 5 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  31 LYS A  33 GLU A  51 LEU A  55 ILE A  63 LEU A 133 ALA A 143	None	0.89A	4c8bB-1h4lA: 22.4	4c8bB-1h4lA: 24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1h4l	CELL DIVISION PROTEIN KINASE 5 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  31 LYS A  33 LEU A  55 ILE A  63 HIS A 124 LEU A 133 ALA A 143	None	0.71A	4c8bB-1h4lA: 22.4	4c8bB-1h4lA: 24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1luf	MUSCLE-SPECIFIC TYROSINE KINASE RECEPTOR MUSK (Rattus norvegicus)	PF07714 (Pkinase_Tyr)	7	ALA A 606 LYS A 608 ILE A 637 HIS A 722 LEU A 731 ALA A 741 ASP A 742	None	0.68A	4c8bB-1lufA: 27.3	4c8bB-1lufA: 27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1opk	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Mus musculus)	PF00017 (SH2) PF00018 (SH3_1) PF07714 (Pkinase_Tyr)	7	ALA A 288 LYS A 290 GLU A 305 THR A 334 HIS A 380 LEU A 389 ALA A 399	P16  A   2 (-3.4A) P16  A   2 (-4.5A) P16  A   2 (-4.2A) P16  A   2 (-3.7A) None P16  A   2 (-4.4A) P16  A   2 (-3.5A)	0.47A	4c8bB-1opkA: 25.6	4c8bB-1opkA: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1py5	TGF-BETA RECEPTOR TYPE I (Homo sapiens)	PF00069 (Pkinase) PF08515 (TGF_beta_GS)	8	ALA A 230 LYS A 232 GLU A 245 ILE A 259 LEU A 260 HIS A 331 LEU A 340 ALA A 350	PY1  A 700 (-3.5A) PY1  A 700 (-3.9A) PY1  A 700 ( 4.9A) None PY1  A 700 (-4.2A) None PY1  A 700 (-4.4A) PY1  A 700 ( 4.2A)	0.66A	4c8bB-1py5A: 18.7	4c8bB-1py5A: 26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1q8y	SR PROTEIN KINASE (Saccharomyces cerevisiae)	PF00069 (Pkinase)	8	ALA A 185 LEU A 206 ILE A 225 LEU A 226 HIS A 292 LEU A 301 ALA A 549 ASP A 550	ADP  A 810 (-3.3A) None None ADP  A 810 (-4.4A) None ADP  A 810 (-4.7A) None ADP  A 810 ( 3.0A)	0.98A	4c8bB-1q8yA: 20.9	4c8bB-1q8yA: 23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1q8y	SR PROTEIN KINASE (Saccharomyces cerevisiae)	PF00069 (Pkinase)	9	ALA A 185 LYS A 187 GLU A 202 LEU A 206 ILE A 225 LEU A 226 HIS A 292 LEU A 301 ALA A 549	ADP  A 810 (-3.3A) ADP  A 810 (-3.1A) None None None ADP  A 810 (-4.4A) None ADP  A 810 (-4.7A) None	0.76A	4c8bB-1q8yA: 20.9	4c8bB-1q8yA: 23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1rjb	FL CYTOKINE RECEPTOR (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 642 LYS A 644 GLU A 661 ILE A 674 HIS A 809 LEU A 818 ASP A 829	None	0.85A	4c8bB-1rjbA: 25.3	4c8bB-1rjbA: 25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 621 LYS A 623 GLU A 640 HIS A 790 LEU A 799 ASP A 810 PHE A 811	STI  A   3 (-3.5A) STI  A   3 (-3.7A) STI  A   3 (-3.6A) STI  A   3 (-4.5A) STI  A   3 (-4.4A) STI  A   3 (-3.9A) STI  A   3 (-3.6A)	0.83A	4c8bB-1t46A: 26.8	4c8bB-1t46A: 26.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	PF07714 (Pkinase_Tyr)	9	ALA A 621 LYS A 623 GLU A 640 LEU A 644 ILE A 653 THR A 670 HIS A 790 LEU A 799 ASP A 810	STI  A   3 (-3.5A) STI  A   3 (-3.7A) STI  A   3 (-3.6A) STI  A   3 (-4.4A) None STI  A   3 (-3.2A) STI  A   3 (-4.5A) STI  A   3 (-4.4A) STI  A   3 (-3.9A)	0.59A	4c8bB-1t46A: 26.8	4c8bB-1t46A: 26.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2buj	SERINE/THREONINE-PRO TEIN KINASE 16 (Homo sapiens)	PF00069 (Pkinase)	8	ALA A  47 LYS A  49 GLU A  65 ILE A  77 LEU A  78 HIS A 146 LEU A 155 ASP A 166	STU  A1301 (-3.6A) STU  A1301 ( 4.0A) None None None None STU  A1301 ( 4.8A) None	0.98A	4c8bB-2bujA: 24.2	4c8bB-2bujA: 26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2jgz	CELL DIVISION PROTEIN KINASE 2 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  31 GLU A  51 LEU A  55 ILE A  63 HIS A 125 LEU A 134 ALA A 144	None	0.77A	4c8bB-2jgzA: 15.8	4c8bB-2jgzA: 25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2jkm	FOCAL ADHESION KINASE 1 (Gallus gallus)	PF07714 (Pkinase_Tyr)	7	ALA A 452 LYS A 454 GLU A 471 ILE A 483 HIS A 544 LEU A 553 ASP A 564	BII  A1687 (-3.5A) BII  A1687 (-2.9A) None None None BII  A1687 (-4.2A) None	0.92A	4c8bB-2jkmA: 27.2	4c8bB-2jkmA: 26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	PF07714 (Pkinase_Tyr)	9	ALA A 271 LYS A 273 GLU A 288 THR A 316 HIS A 362 LEU A 371 ALA A 381 ASP A 382 PHE A 383	1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.6A) 1N8  A 501 ( 3.3A) None 1N8  A 501 ( 4.3A) 1N8  A 501 ( 3.3A) 1N8  A 501 ( 3.3A) 1N8  A 501 ( 4.3A)	0.65A	4c8bB-2og8A: 27.1	4c8bB-2og8A: 26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 614 GLU A 633 ILE A 646 THR A 663 HIS A 776 LEU A 785 ASP A 796	None	0.86A	4c8bB-2ogvA: 25.2	4c8bB-2ogvA: 26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2p4i	ANGIOPOIETIN-1 RECEPTOR (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 853 ILE A 885 HIS A 962 LEU A 971 ALA A 981 ASP A 982 PHE A 983	MR9  A 301 (-3.5A) MR9  A 301 ( 4.5A) MR9  A 301 (-4.5A) MR9  A 301 (-4.5A) MR9  A 301 (-3.2A) MR9  A 301 (-4.2A) MR9  A 301 (-4.4A)	0.77A	4c8bB-2p4iA: 11.4	4c8bB-2p4iA: 25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2phk	PHOSPHORYLASE KINASE (Oryctolagus cuniculus)	PF00069 (Pkinase)	7	ALA A  46 LYS A  48 GLU A  73 LEU A  77 ILE A  86 HIS A 147 LEU A 156	ATP  A 381 (-3.5A) ATP  A 381 (-3.2A) None None None None ATP  A 381 ( 4.8A)	0.80A	4c8bB-2phkA: 23.9	4c8bB-2phkA: 26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2qlu	ACTIVIN RECEPTOR TYPE IIB (Homo sapiens)	PF00069 (Pkinase)	7	ALA A 215 LYS A 217 LEU A 245 THR A 265 HIS A 319 LEU A 328 ALA A 338	ADE  A 488 (-3.2A) None ADE  A 488 ( 4.5A) ADE  A 488 (-4.3A) None ADE  A 488 (-4.4A) None	0.52A	4c8bB-2qluA: 24.9	4c8bB-2qluA: 27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2qr7	RIBOSOMAL PROTEIN S6 KINASE ALPHA-3 (Mus musculus)	PF00069 (Pkinase)	7	ALA A 449 LYS A 451 GLU A 463 LEU A 467 ILE A 476 THR A 493 HIS A 537	None	0.59A	4c8bB-2qr7A: 20.3	4c8bB-2qr7A: 25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2vd5	DMPK PROTEIN (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  98 LYS A 100 GLU A 119 LEU A 123 ILE A 131 LEU A 202 ALA A 212	BI8  A1417 ( 3.8A) BI8  A1417 (-4.2A) BI8  A1417 ( 4.9A) None None BI8  A1417 (-4.8A) BI8  A1417 ( 4.1A)	0.79A	4c8bB-2vd5A: 21.4	4c8bB-2vd5A: 23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2vd5	DMPK PROTEIN (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  98 LYS A 100 LEU A 123 ILE A 131 HIS A 193 LEU A 202 ALA A 212	BI8  A1417 ( 3.8A) BI8  A1417 (-4.2A) None None None BI8  A1417 (-4.8A) BI8  A1417 ( 4.1A)	0.68A	4c8bB-2vd5A: 21.4	4c8bB-2vd5A: 23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2xik	SERINE/THREONINE PROTEIN KINASE 25 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  47 GLU A  66 LEU A  70 ILE A  78 HIS A 138 LEU A 147 ALA A 157	J60  A1294 (-3.3A) None None None None J60  A1294 (-4.8A) J60  A1294 ( 4.2A)	0.60A	4c8bB-2xikA: 17.9	4c8bB-2xikA: 26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2xik	SERINE/THREONINE PROTEIN KINASE 25 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  47 LYS A  49 GLU A  66 LEU A  70 HIS A 138 LEU A 147 ALA A 157	J60  A1294 (-3.3A) None None None None J60  A1294 (-4.8A) J60  A1294 ( 4.2A)	0.81A	4c8bB-2xikA: 17.9	4c8bB-2xikA: 26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2xyu	EPHRIN TYPE-A RECEPTOR 4, (Mus musculus)	PF07714 (Pkinase_Tyr)	7	ALA A 651 LYS A 653 ILE A 682 THR A 699 HIS A 744 LEU A 753 ASP A 764	Q9G  A1898 (-3.2A) Q9G  A1898 (-4.8A) None Q9G  A1898 (-3.5A) None Q9G  A1898 (-4.3A) None	0.79A	4c8bB-2xyuA: 27.8	4c8bB-2xyuA: 28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3c4f	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 512 GLU A 531 ILE A 544 HIS A 621 LEU A 630 ALA A 640 PHE A 489	C4F  A   1 (-3.3A) None None None C4F  A   1 (-4.6A) C4F  A   1 (-3.6A) C4F  A   1 (-3.7A)	0.85A	4c8bB-3c4fA: 26.5	4c8bB-3c4fA: 26.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3dko	EPHRIN TYPE-A RECEPTOR 7 (Homo sapiens)	PF07714 (Pkinase_Tyr) PF14575 (EphA2_TM)	7	ALA A 663 LYS A 665 GLU A 682 HIS A 756 LEU A 765 ASP A 776 PHE A 777	IHZ  A1001 (-3.3A) IHZ  A1001 ( 4.5A) IHZ  A1001 (-3.8A) IHZ  A1001 ( 4.9A) IHZ  A1001 (-4.6A) IHZ  A1001 (-4.8A) IHZ  A1001 (-4.7A)	0.83A	4c8bB-3dkoA: 27.0	4c8bB-3dkoA: 26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3e7o	MITOGEN-ACTIVATED PROTEIN KINASE 9 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  53 LYS A  55 GLU A  73 LEU A  77 ILE A  85 HIS A 149 ASP A 169	35F  A   1 (-3.6A) 35F  A   1 ( 4.6A) None None None None None	0.96A	4c8bB-3e7oA: 21.1	4c8bB-3e7oA: 23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3gp0	MITOGEN-ACTIVATED PROTEIN KINASE 11 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  51 LYS A  53 GLU A  71 LEU A  75 THR A 106 HIS A 148 ASP A 168	NIL  A   1 (-3.7A) None NIL  A   1 (-3.7A) NIL  A   1 ( 4.8A) NIL  A   1 (-3.3A) NIL  A   1 (-4.3A) NIL  A   1 (-4.6A)	0.71A	4c8bB-3gp0A: 22.0	4c8bB-3gp0A: 25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3hng	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 859 LYS A 861 GLU A 878 HIS A1020 LEU A1029 ASP A1040 PHE A1041	8ST  A2001 ( 3.8A) 8ST  A2001 (-4.0A) 8ST  A2001 (-3.7A) 8ST  A2001 ( 4.8A) None None 8ST  A2001 ( 3.7A)	0.83A	4c8bB-3hngA: 25.9	4c8bB-3hngA: 24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3hng	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 859 LYS A 861 GLU A 878 LEU A 882 HIS A1020 LEU A1029 ASP A1040	8ST  A2001 ( 3.8A) 8ST  A2001 (-4.0A) 8ST  A2001 (-3.7A) None 8ST  A2001 ( 4.8A) None None	0.77A	4c8bB-3hngA: 25.9	4c8bB-3hngA: 24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3iec	SERINE/THREONINE-PRO TEIN KINASE MARK2 (Homo sapiens)	PF00069 (Pkinase) PF00627 (UBA)	7	ALA A  80 LYS A  82 ILE A 112 HIS A 173 LEU A 182 ALA A 192 ASP A 193	None	0.83A	4c8bB-3iecA: 22.6	4c8bB-3iecA: 26.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3kul	EPHRIN TYPE-A RECEPTOR 8 (Homo sapiens)	PF07714 (Pkinase_Tyr) PF14575 (EphA2_TM)	7	ALA A 665 LYS A 667 GLU A 684 ILE A 696 THR A 713 HIS A 758 LEU A 767	None	0.56A	4c8bB-3kulA: 27.2	4c8bB-3kulA: 31.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3llt	SERINE/THREONINE KINASE-1, PFLAMMER (Plasmodium falciparum)	PF00069 (Pkinase)	8	ALA A 579 LYS A 581 GLU A 596 LEU A 600 ILE A 613 HIS A 675 LEU A 684 ASP A 720	ANP  A 877 ( 3.7A) ANP  A 877 (-2.7A) ANP  A 877 ( 4.4A) None None None None ANP  A 877 (-2.9A)	1.06A	4c8bB-3lltA: 20.8	4c8bB-3lltA: 28.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3mdy	BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B (Homo sapiens)	PF07714 (Pkinase_Tyr) PF08515 (TGF_beta_GS)	8	ALA A 229 LYS A 231 GLU A 244 ILE A 258 LEU A 259 THR A 279 LEU A 339 ALA A 349	LDN  A   1 (-3.6A) None None None None LDN  A   1 (-3.8A) LDN  A   1 (-4.5A) LDN  A   1 ( 3.8A)	0.59A	4c8bB-3mdyA: 25.1	4c8bB-3mdyA: 27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3mdy	BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B (Homo sapiens)	PF07714 (Pkinase_Tyr) PF08515 (TGF_beta_GS)	8	ALA A 229 LYS A 231 ILE A 258 LEU A 259 THR A 279 HIS A 330 LEU A 339 ALA A 349	LDN  A   1 (-3.6A) None None None LDN  A   1 (-3.8A) None LDN  A   1 (-4.5A) LDN  A   1 ( 3.8A)	0.54A	4c8bB-3mdyA: 25.1	4c8bB-3mdyA: 27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3mi9	CELL DIVISION PROTEIN KINASE 9 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  46 LYS A  48 GLU A  66 LEU A  70 HIS A 147 LEU A 156 ALA A 166	None	0.76A	4c8bB-3mi9A: 16.5	4c8bB-3mi9A: 24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3my0	SERINE/THREONINE-PRO TEIN KINASE RECEPTOR R3 (Homo sapiens)	PF07714 (Pkinase_Tyr)	8	ALA A 227 LYS A 229 ILE A 256 LEU A 257 THR A 277 HIS A 328 LEU A 337 ALA A 347	LDN  A 600 (-3.2A) LDN  A 600 (-4.0A) None None LDN  A 600 (-4.0A) None LDN  A 600 (-4.6A) LDN  A 600 ( 3.8A)	0.73A	4c8bB-3my0A: 24.0	4c8bB-3my0A: 27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3my0	SERINE/THREONINE-PRO TEIN KINASE RECEPTOR R3 (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ILE A 256 LEU A 257 THR A 277 HIS A 328 LEU A 337 ALA A 347 ASP A 348	None None LDN  A 600 (-4.0A) None LDN  A 600 (-4.6A) LDN  A 600 ( 3.8A) None	0.81A	4c8bB-3my0A: 24.0	4c8bB-3my0A: 27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3n9x	PHOSPHOTRANSFERASE (Plasmodium berghei)	PF00069 (Pkinase)	7	ALA A  55 LYS A  57 GLU A  75 LEU A  79 ILE A  87 HIS A 152 LEU A 161	GOL  A 434 ( 4.1A) GOL  A 433 (-3.2A) GOL  A 433 ( 4.8A) None None None GOL  A 434 (-4.2A)	0.80A	4c8bB-3n9xA: 12.1	4c8bB-3n9xA: 28.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3nie	MAP2 KINASE (Plasmodium falciparum)	PF00069 (Pkinase)	7	ALA A  57 LYS A  59 GLU A  77 LEU A  81 ILE A  89 HIS A 154 LEU A 163	ANP  A 430 (-3.5A) ANP  A 430 (-2.5A) ANP  A 430 ( 4.4A) None None None ANP  A 430 (-4.4A)	0.82A	4c8bB-3nieA: 20.9	4c8bB-3nieA: 27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3niz	RHODANESE FAMILY PROTEIN (Cryptosporidium parvum)	PF00069 (Pkinase)	7	ALA A  49 LEU A  73 ILE A  81 HIS A 142 LEU A 151 ALA A 161 ASP A 162	ADP  A 314 (-3.5A) None None None ADP  A 314 (-4.6A) None MG  A 312 ( 3.3A)	0.98A	4c8bB-3nizA: 23.9	4c8bB-3nizA: 28.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3niz	RHODANESE FAMILY PROTEIN (Cryptosporidium parvum)	PF00069 (Pkinase)	7	ALA A  49 LYS A  51 GLU A  69 LEU A  73 ILE A  81 LEU A 151 ALA A 161	ADP  A 314 (-3.5A) ADP  A 314 (-2.8A) None None None ADP  A 314 (-4.6A) None	0.78A	4c8bB-3nizA: 23.9	4c8bB-3nizA: 28.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3niz	RHODANESE FAMILY PROTEIN (Cryptosporidium parvum)	PF00069 (Pkinase)	7	ALA A  49 LYS A  51 LEU A  73 ILE A  81 HIS A 142 LEU A 151 ALA A 161	ADP  A 314 (-3.5A) ADP  A 314 (-2.8A) None None None ADP  A 314 (-4.6A) None	0.66A	4c8bB-3nizA: 23.9	4c8bB-3nizA: 28.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3oz6	MITOGEN-ACTIVATED PROTEIN KINASE 1, SERINE/THREONINE PROTEIN KINASE (Cryptosporidium parvum)	PF00069 (Pkinase)	7	ALA A  38 GLU A  58 LEU A  62 ILE A  71 HIS A 132 LEU A 141 ALA A 151	None	0.81A	4c8bB-3oz6A: 20.6	4c8bB-3oz6A: 22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3oz6	MITOGEN-ACTIVATED PROTEIN KINASE 1, SERINE/THREONINE PROTEIN KINASE (Cryptosporidium parvum)	PF00069 (Pkinase)	7	ALA A  38 LYS A  40 LEU A  62 ILE A  71 HIS A 132 LEU A 141 ALA A 151	None	0.87A	4c8bB-3oz6A: 20.6	4c8bB-3oz6A: 22.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ppz	SERINE/THREONINE-PRO TEIN KINASE CTR1 (Arabidopsis thaliana)	PF07714 (Pkinase_Tyr)	7	ALA A 576 LYS A 578 GLU A 596 ILE A 608 THR A 625 HIS A 674 LEU A 683	STU  A   1 (-3.3A) STU  A   1 (-3.5A) None None STU  A   1 (-4.1A) None STU  A   1 (-4.3A)	0.54A	4c8bB-3ppzA: 28.3	4c8bB-3ppzA: 36.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3q4t	ACTIVIN RECEPTOR TYPE-2A (Homo sapiens)	PF00069 (Pkinase)	7	ALA A 217 ILE A 246 LEU A 247 THR A 267 HIS A 320 LEU A 329 ALA A 339	TAK  A   2 (-3.5A) None None TAK  A   2 (-3.5A) None TAK  A   2 (-4.6A) TAK  A   2 ( 4.2A)	0.52A	4c8bB-3q4tA: 24.6	4c8bB-3q4tA: 32.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3q5i	PROTEIN KINASE (Plasmodium berghei)	PF00069 (Pkinase) PF13499 (EF-hand_7)	7	ALA A  84 LYS A  86 GLU A 115 ILE A 127 THR A 144 HIS A 188 LEU A 197	ANP  A1634 (-3.6A) ANP  A1634 (-3.1A) None None ANP  A1634 (-4.6A) None ANP  A1634 (-4.4A)	0.79A	4c8bB-3q5iA: 21.3	4c8bB-3q5iA: 24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3q5i	PROTEIN KINASE (Plasmodium berghei)	PF00069 (Pkinase) PF13499 (EF-hand_7)	7	ALA A  84 LYS A  86 GLU A 115 LEU A 119 THR A 144 HIS A 188 LEU A 197	ANP  A1634 (-3.6A) ANP  A1634 (-3.1A) None None ANP  A1634 (-4.6A) None ANP  A1634 (-4.4A)	0.92A	4c8bB-3q5iA: 21.3	4c8bB-3q5iA: 24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qfv	CDC42BPB PROTEIN (Homo sapiens)	PF00069 (Pkinase)	7	ALA A 103 LYS A 105 GLU A 124 LEU A 128 ILE A 136 LEU A 207 ALA A 217	NM7  A 416 ( 3.7A) EDO  A 417 (-3.5A) EDO  A 417 (-4.0A) None None NM7  A 416 ( 4.2A) NM7  A 416 ( 4.5A)	0.73A	4c8bB-3qfvA: 16.6	4c8bB-3qfvA: 23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qfv	CDC42BPB PROTEIN (Homo sapiens)	PF00069 (Pkinase)	7	ALA A 103 LYS A 105 LEU A 128 ILE A 136 HIS A 198 LEU A 207 ALA A 217	NM7  A 416 ( 3.7A) EDO  A 417 (-3.5A) None None None NM7  A 416 ( 4.2A) NM7  A 416 ( 4.5A)	0.66A	4c8bB-3qfvA: 16.6	4c8bB-3qfvA: 23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3s95	LIM DOMAIN KINASE 1 (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	LYS A 368 GLU A 384 LEU A 397 THR A 413 HIS A 458 LEU A 467 ALA A 477	STU  A   1 (-3.1A) STU  A   1 (-3.7A) STU  A   1 (-4.6A) STU  A   1 (-3.9A) None STU  A   1 (-4.6A) STU  A   1 ( 4.1A)	0.79A	4c8bB-3s95A: 25.2	4c8bB-3s95A: 23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3tt0	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 512 LYS A 514 GLU A 531 ILE A 544 HIS A 621 LEU A 630 ALA A 640	07J  A   1 (-3.5A) 07J  A   1 (-4.5A) 07J  A   1 (-3.8A) None None 07J  A   1 ( 4.4A) 07J  A   1 (-3.2A)	0.62A	4c8bB-3tt0A: 26.5	4c8bB-3tt0A: 27.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3v5q	NT-3 GROWTH FACTOR RECEPTOR (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 570 GLU A 588 LEU A 592 ILE A 600 HIS A 677 LEU A 686 ASP A 697	0F4  A 902 (-3.2A) 0F4  A 902 (-3.6A) 0F4  A 902 (-4.7A) 0F4  A 902 (-4.1A) 0F4  A 902 (-4.1A) 0F4  A 902 (-4.5A) None	0.86A	4c8bB-3v5qA: 26.7	4c8bB-3v5qA: 29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4agu	CYCLIN-DEPENDENT KINASE-LIKE 1 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  31 LYS A  33 GLU A  51 LEU A  55 HIS A 124 LEU A 133 ASP A 144	D15  A 500 (-3.4A) D15  A 500 ( 4.1A) None None None D15  A 500 (-4.5A) D15  A 500 (-3.7A)	0.92A	4c8bB-4aguA: 24.2	4c8bB-4aguA: 23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4aw2	SERINE/THREONINE-PRO TEIN KINASE MRCK ALPHA (Rattus norvegicus)	PF00069 (Pkinase) PF00433 (Pkinase_C)	8	ALA A 104 LYS A 106 GLU A 125 LEU A 129 ILE A 137 HIS A 199 LEU A 208 ALA A 218	EDO  A1420 (-3.4A) EDO  A1419 (-3.3A) EDO  A1419 (-3.0A) None None None EDO  A1420 ( 4.8A) None	0.71A	4c8bB-4aw2A: 21.1	4c8bB-4aw2A: 24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4b99	MITOGEN-ACTIVATED PROTEIN KINASE 7 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  82 LYS A  84 LEU A 106 ILE A 114 HIS A 180 LEU A 189 ASP A 200	R4L  A1394 ( 3.7A) None None None None R4L  A1394 (-4.5A) None	0.88A	4c8bB-4b99A: 22.3	4c8bB-4b99A: 24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4bc6	SERINE/THREONINE-PRO TEIN KINASE 10 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  63 GLU A  81 LEU A  85 ILE A  93 HIS A 155 LEU A 164 ALA A 174	XZN  A1317 (-3.5A) XZN  A1317 (-3.9A) None None None XZN  A1317 (-4.7A) XZN  A1317 ( 4.3A)	0.69A	4c8bB-4bc6A: 23.4	4c8bB-4bc6A: 27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4bgq	CYCLIN-DEPENDENT KINASE-LIKE 5 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  40 LYS A  42 LEU A  64 ILE A  72 HIS A 133 LEU A 142 ASP A 153	38R  A1000 (-3.4A) 38R  A1000 (-3.4A) None None None 38R  A1000 ( 4.5A) 38R  A1000 ( 4.2A)	1.06A	4c8bB-4bgqA: 22.4	4c8bB-4bgqA: 27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4c02	ACTIVIN RECEPTOR TYPE-1 (Homo sapiens)	PF00069 (Pkinase) PF08515 (TGF_beta_GS)	8	ALA A 233 LYS A 235 ILE A 262 LEU A 263 THR A 283 HIS A 334 LEU A 343 ALA A 353	TAK  A1507 (-3.3A) TAK  A1507 ( 4.5A) None FLC  A1503 ( 4.5A) TAK  A1507 (-3.6A) None TAK  A1507 (-4.7A) TAK  A1507 ( 4.2A)	0.69A	4c8bB-4c02A: 24.2	4c8bB-4c02A: 27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4cfh	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (Rattus norvegicus)	PF00069 (Pkinase) PF16579 (AdenylateSensor)	7	ALA A  43 LYS A  45 GLU A  64 LEU A  68 ILE A  76 LEU A 146 ALA A 156	STU  A1550 (-3.1A) STU  A1550 (-3.6A) None None None STU  A1550 (-4.3A) STU  A1550 ( 3.8A)	0.75A	4c8bB-4cfhA: 23.5	4c8bB-4cfhA: 26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4cfh	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (Rattus norvegicus)	PF00069 (Pkinase) PF16579 (AdenylateSensor)	7	ALA A  43 LYS A  45 LEU A  68 ILE A  76 HIS A 137 LEU A 146 ALA A 156	STU  A1550 (-3.1A) STU  A1550 (-3.6A) None None None STU  A1550 (-4.3A) STU  A1550 ( 3.8A)	0.76A	4c8bB-4cfhA: 23.5	4c8bB-4cfhA: 26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	PF07714 (Pkinase_Tyr)	9	ALA A 653 GLU A 672 ILE A 684 THR A 701 HIS A 764 LEU A 773 ALA A 783 ASP A 784 PHE A 785	DI1  A1000 (-3.6A) DI1  A1000 (-3.8A) DI1  A1000 ( 4.5A) DI1  A1000 (-3.6A) DI1  A1000 (-3.8A) DI1  A1000 (-4.5A) DI1  A1000 (-3.7A) DI1  A1000 (-4.1A) DI1  A1000 (-4.5A)	0.67A	4c8bB-4ckrA: 25.5	4c8bB-4ckrA: 26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	PF07714 (Pkinase_Tyr)	9	ALA A 653 LYS A 655 GLU A 672 ILE A 684 THR A 701 HIS A 764 LEU A 773 ALA A 783 ASP A 784	DI1  A1000 (-3.6A) DI1  A1000 (-3.9A) DI1  A1000 (-3.8A) DI1  A1000 ( 4.5A) DI1  A1000 (-3.6A) DI1  A1000 (-3.8A) DI1  A1000 (-4.5A) DI1  A1000 (-3.7A) DI1  A1000 (-4.1A)	0.49A	4c8bB-4ckrA: 25.5	4c8bB-4ckrA: 26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	PF07714 (Pkinase_Tyr)	8	ALA A 853 LYS A 855 GLU A 871 LEU A 875 ILE A 883 HIS A 947 LEU A 956 ALA A 966	19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.53A	4c8bB-4hviA: 18.7	4c8bB-4hviA: 29.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	PF07714 (Pkinase_Tyr)	8	LYS A 855 GLU A 871 LEU A 875 ILE A 883 HIS A 947 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.5A) None None None None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.97A	4c8bB-4hviA: 18.7	4c8bB-4hviA: 29.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4k33	FIBROBLAST GROWTH FACTOR RECEPTOR 3 (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 506 LYS A 508 GLU A 525 ILE A 538 HIS A 615 LEU A 624 ALA A 634	ACP  A 801 (-3.3A) ACP  A 801 (-2.7A) ACP  A 801 ( 4.8A) None None ACP  A 801 (-4.4A) None	0.83A	4c8bB-4k33A: 26.2	4c8bB-4k33A: 30.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4l52	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7, TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1 CHIMERA (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A  61 LYS A  63 GLU A  77 LEU A  81 ILE A  89 HIS A 154 LEU A 163	1UL  A 501 (-3.1A) None None None None None 1UL  A 501 (-4.3A)	0.81A	4c8bB-4l52A: 28.8	4c8bB-4l52A: 29.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4m69	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 3 (Mus musculus)	PF00069 (Pkinase)	7	ALA A  49 LYS A  51 LEU A  74 THR A  95 HIS A 141 LEU A 150 ALA A 160	ANP  A 401 (-3.1A) ANP  A 401 (-2.9A) None ANP  A 401 (-3.8A) None ANP  A 401 (-4.8A) None	0.93A	4c8bB-4m69A: 29.0	4c8bB-4m69A: 34.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4o27	SERINE/THREONINE-PRO TEIN KINASE 24 (Homo sapiens)	PF00069 (Pkinase)	7	ALA B  51 LYS B  53 GLU B  70 LEU B  74 HIS B 142 LEU B 151 ALA B 161	ADP  B 500 (-3.3A) ADP  B 500 (-3.1A) None None None ADP  B 500 (-4.7A) None	0.63A	4c8bB-4o27B: 24.8	4c8bB-4o27B: 26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4o27	SERINE/THREONINE-PRO TEIN KINASE 24 (Homo sapiens)	PF00069 (Pkinase)	7	ALA B  51 LYS B  53 LEU B  74 HIS B 142 LEU B 151 ALA B 161 ASP B 162	ADP  B 500 (-3.3A) ADP  B 500 (-3.1A) None None ADP  B 500 (-4.7A) None ADP  B 500 ( 3.4A)	0.84A	4c8bB-4o27B: 24.8	4c8bB-4o27B: 26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  67 LYS A  69 GLU A  85 ILE A  98 THR A 123 HIS A 171 LEU A 180	SIN  A 401 ( 3.7A) None None None None None SIN  A 401 ( 4.5A)	0.68A	4c8bB-4o38A: 21.3	4c8bB-4o38A: 25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4rew	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (Homo sapiens)	PF00069 (Pkinase) PF16579 (AdenylateSensor)	7	ALA A  45 LYS A  47 LEU A  70 ILE A  78 HIS A 139 LEU A 148 ALA A 158	STU  A 601 (-3.2A) STU  A 601 ( 3.7A) None None None STU  A 601 (-4.2A) STU  A 601 ( 3.8A)	0.93A	4c8bB-4rewA: 23.0	4c8bB-4rewA: 21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	PF07714 (Pkinase_Tyr)	8	ALA A 642 LYS A 644 GLU A 661 ILE A 674 HIS A 809 LEU A 818 ASP A 829 PHE A 830	P30  A1001 (-3.4A) P30  A1001 (-3.4A) P30  A1001 (-3.6A) None P30  A1001 ( 4.3A) P30  A1001 (-4.6A) None P30  A1001 (-3.9A)	0.77A	4c8bB-4rt7A: 19.9	4c8bB-4rt7A: 26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ueu	TYROSINE KINASE AS - A COMMON ANCESTOR OF SRC AND ABL (synthetic construct)	PF07714 (Pkinase_Tyr)	7	ALA A  35 LYS A  37 THR A  81 HIS A 127 LEU A 136 ALA A 146 ASP A 147	ACP  A1264 (-2.9A) None ACP  A1264 (-4.5A) None ACP  A1264 ( 4.8A) None None	0.75A	4c8bB-4ueuA: 27.0	4c8bB-4ueuA: 26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4xcu	FIBROBLAST GROWTH FACTOR RECEPTOR 4 (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 501 LYS A 503 GLU A 520 ILE A 533 HIS A 610 LEU A 619 ALA A 629	40M  A1002 ( 4.1A) 40M  A1002 (-4.0A) 40M  A1002 (-3.7A) None None 40M  A1002 (-4.5A) 40M  A1002 (-3.0A)	0.73A	4c8bB-4xcuA: 26.0	4c8bB-4xcuA: 24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	PF07714 (Pkinase_Tyr)	8	ALA A 642 LYS A 644 GLU A 661 ILE A 674 HIS A 809 LEU A 818 ASP A 829 PHE A 830	P30  A1001 (-3.5A) P30  A1001 ( 4.0A) P30  A1001 (-3.1A) P30  A1001 (-4.3A) P30  A1001 (-4.4A) P30  A1001 (-4.3A) None P30  A1001 ( 4.1A)	0.75A	4c8bB-4xufA: 26.0	4c8bB-4xufA: 27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4yff	SERINE/THREONINE-PRO TEIN KINASE TNNI3K (Homo sapiens)	PF07714 (Pkinase_Tyr)	8	ALA A 488 LYS A 490 GLU A 509 LEU A 513 THR A 539 HIS A 586 LEU A 595 ALA A 605	4CV  A 801 (-3.5A) 4CV  A 801 (-3.9A) None None 4CV  A 801 (-2.8A) None 4CV  A 801 (-4.4A) 4CV  A 801 ( 3.9A)	0.93A	4c8bB-4yffA: 25.2	4c8bB-4yffA: 29.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ysj	CALMODULIN-LIKE DOMAIN PROTEIN KINASE (Eimeria tenella)	PF00069 (Pkinase) PF13499 (EF-hand_7)	8	ALA A  55 LYS A  57 GLU A  76 LEU A  80 ILE A  88 THR A 105 HIS A 149 LEU A 158	ADP  A 506 (-3.3A) ADP  A 506 (-2.4A) None None None ADP  A 506 ( 4.6A) None ADP  A 506 (-4.7A)	0.81A	4c8bB-4ysjA: 24.1	4c8bB-4ysjA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 512 LYS A 514 GLU A 531 ILE A 544 HIS A 621 LEU A 630 ALA A 640	38O  A1769 (-3.6A) 38O  A1769 ( 3.1A) EDO  A1766 (-4.1A) None None 38O  A1769 (-4.6A) EDO  A1766 ( 4.4A)	0.67A	4c8bB-5a46A: 20.0	4c8bB-5a46A: 25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5d7a	TRAF2 AND NCK-INTERACTING PROTEIN KINASE (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  52 LYS A  54 GLU A  69 LEU A  73 ILE A  82 HIS A 151 LEU A 160	ALA  A  52 (-0.0A) LYS  A  54 ( 0.0A) GLU  A  69 ( 0.6A) LEU  A  73 ( 0.6A) ILE  A  82 ( 0.7A) HIS  A 151 ( 1.0A) LEU  A 160 (-0.6A)	0.91A	4c8bB-5d7aA: 25.6	4c8bB-5d7aA: 25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5e8y	TGF-BETA RECEPTOR TYPE-2 (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 275 LYS A 277 GLU A 290 ILE A 304 LEU A 305 THR A 325 LEU A 386	STU  A 601 (-3.1A) STU  A 601 (-2.4A) STU  A 601 ( 3.8A) None STU  A 601 ( 3.8A) STU  A 601 ( 3.7A) STU  A 601 (-3.9A)	0.66A	4c8bB-5e8yA: 18.1	4c8bB-5e8yA: 27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5e8y	TGF-BETA RECEPTOR TYPE-2 (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 275 LYS A 277 ILE A 304 LEU A 305 THR A 325 HIS A 377 LEU A 386	STU  A 601 (-3.1A) STU  A 601 (-2.4A) None STU  A 601 ( 3.8A) STU  A 601 ( 3.7A) None STU  A 601 (-3.9A)	0.56A	4c8bB-5e8yA: 18.1	4c8bB-5e8yA: 27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5es1	MAP/MICROTUBULE AFFINITY-REGULATING KINASE 4 (Homo sapiens)	PF00069 (Pkinase) PF00627 (UBA)	7	ALA A  83 LYS A  85 GLU A 103 ILE A 115 HIS A 176 LEU A 185 ALA A 195	5RC  A4000 (-3.6A) 5RC  A4000 (-2.8A) None None None None 5RC  A4000 ( 3.9A)	0.82A	4c8bB-5es1A: 23.0	4c8bB-5es1A: 27.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5eyk	AURORA KINASE B-A (Xenopus laevis)	PF00069 (Pkinase)	7	ALA A 120 LYS A 122 ILE A 153 LEU A 154 LEU A 223 ALA A 233 ASP A 234	5U5  A 401 (-3.5A) 5U5  A 401 (-2.6A) None 5U5  A 401 (-4.8A) 5U5  A 401 (-4.7A) None None	0.83A	4c8bB-5eykA: 23.3	4c8bB-5eykA: 24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	PF07714 (Pkinase_Tyr)	8	ALA A 625 LYS A 627 GLU A 644 ILE A 657 HIS A 816 LEU A 825 ASP A 836 PHE A 837	748  A1001 (-3.7A) 748  A1001 (-4.0A) 748  A1001 (-3.3A) 748  A1001 ( 4.4A) 748  A1001 (-3.8A) 748  A1001 (-4.3A) 748  A1001 (-4.8A) 748  A1001 (-3.7A)	0.76A	4c8bB-5grnA: 19.9	4c8bB-5grnA: 27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	PF07714 (Pkinase_Tyr)	8	ALA A 625 LYS A 627 GLU A 644 ILE A 657 THR A 674 HIS A 816 LEU A 825 ASP A 836	748  A1001 (-3.7A) 748  A1001 (-4.0A) 748  A1001 (-3.3A) 748  A1001 ( 4.4A) 748  A1001 (-3.2A) 748  A1001 (-3.8A) 748  A1001 (-4.3A) 748  A1001 (-4.8A)	0.48A	4c8bB-5grnA: 19.9	4c8bB-5grnA: 27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5hu3	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE II ALPHA CHAIN (Drosophila melanogaster)	PF00069 (Pkinase)	7	ALA A  41 LYS A  43 GLU A  61 ILE A  73 HIS A 134 LEU A 143 ALA A 156	ADP  A 301 (-3.5A) ADP  A 301 (-2.7A) None None None ADP  A 301 (-4.7A) ADP  A 301 ( 4.8A)	0.58A	4c8bB-5hu3A: 24.4	4c8bB-5hu3A: 24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A  43 LYS A  45 GLU A  61 ILE A  73 HIS A 134 LEU A 143 ALA A 153	6G2  A 901 (-3.2A) 6G2  A 901 ( 3.9A) None None None 6G2  A 901 (-4.7A) 6G2  A 901 ( 4.2A)	0.56A	4c8bB-5j5tA: 11.2	4c8bB-5j5tA: 25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ko1	MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN (Homo sapiens)	PF07714 (Pkinase_Tyr)	7	ALA A 228 LYS A 230 ILE A 262 LEU A 263 HIS A 329 LEU A 338 ALA A 348	6UY  A 501 (-3.4A) 6UY  A 501 (-4.0A) None None None 6UY  A 501 (-4.5A) 6UY  A 501 (-3.4A)	0.67A	4c8bB-5ko1A: 27.1	4c8bB-5ko1A: 28.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	PF00069 (Pkinase)	7	ALA A 119 LYS A 121 GLU A 136 LEU A 140 HIS A 223 LEU A 232 ALA A 540	W4A  A 716 ( 3.9A) SO4  A 702 (-3.3A) DMS  A 717 (-4.0A) None None None DMS  A 717 ( 4.5A)	0.85A	4c8bB-5myvA: 19.9	4c8bB-5myvA: 22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5xv7	SERINE-ARGININE (SR) PROTEIN KINASE 1 (Homo sapiens)	no annotation	7	ALA A 107 LYS A 109 GLU A 124 LEU A 128 HIS A 211 LEU A 220 ALA A 496	EMH  A 705 (-3.6A) EMH  A 705 ( 4.8A) None None None None EMH  A 705 ( 4.0A)	0.88A	4c8bB-5xv7A: 20.5	4c8bB-5xv7A: 12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5xzw	SERINE/THREONINE-PRO TEIN KINASE RAD53 (Saccharomyces cerevisiae)	no annotation	7	ALA A 225 LYS A 227 GLU A 244 LEU A 248 ILE A 256 HIS A 317 LEU A 326	None	0.79A	4c8bB-5xzwA: 19.2	4c8bB-5xzwA: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6b3e	CYCLIN-DEPENDENT KINASE 12 (Homo sapiens)	no annotation	7	ALA A 754 LYS A 756 GLU A 774 LEU A 778 HIS A 857 LEU A 866 ALA A 876	CJM  A1102 (-3.1A) None None None None CJM  A1102 (-4.4A) CJM  A1102 (-3.6A)	0.81A	4c8bB-6b3eA: 24.0	4c8bB-6b3eA: 12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	no annotation	7	ALA A 192 LYS A 194 LEU A 240 HIS A 310 LEU A 319 ALA A 329 ASP A 330	BI9  A 501 (-3.3A) NH4  A 506 ( 4.4A) None None BI9  A 501 (-4.7A) NH4  A 506 ( 3.7A) None	0.89A	4c8bB-6bqlA: 22.7	4c8bB-6bqlA: 14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6c7y	TYROSINE-PROTEIN KINASE JAK1 (Homo sapiens)	no annotation	7	ALA A 906 LYS A 908 GLU A 925 LEU A 929 ILE A 937 HIS A1001 LEU A1010	ADP  A1201 (-3.4A) ADP  A1201 (-2.8A) None None None None ADP  A1201 (-4.5A)	0.67A	4c8bB-6c7yA: 24.5	4c8bB-6c7yA: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6c9d	SERINE/THREONINE-PRO TEIN KINASE MARK1,SERINE/THREONI NE-PROTEIN KINASE MARK1 (Homo sapiens)	no annotation	7	ALA A  87 LYS A  89 GLU A 107 ILE A 119 HIS A 180 LEU A 189 ALA A 199	None	0.73A	4c8bB-6c9dA: 22.2	4c8bB-6c9dA: 11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	no annotation	7	ALA A 192 LYS A 194 GLU A 236 LEU A 240 HIS A 310 LEU A 319 ALA A 329	F6J  A 501 (-3.4A) F6J  A 501 (-2.9A) F6J  A 501 ( 4.7A) None None F6J  A 501 (-4.5A) F6J  A 501 ( 4.0A)	0.93A	4c8bB-6cmjA: 16.4	4c8bB-6cmjA: 15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6cnh	SERINE/THREONINE-PRO TEIN KINASE PRP4 HOMOLOG (Homo sapiens)	no annotation	9	ALA A 715 LYS A 717 GLU A 732 LEU A 736 LEU A 751 HIS A 813 LEU A 822 ASP A 834 PHE A 835	919  A1101 (-3.5A) SO4  A1102 ( 2.8A) 919  A1101 (-3.7A) None 919  A1101 (-4.5A) 919  A1101 (-4.2A) None 919  A1101 (-4.5A) 919  A1101 ( 4.1A)	0.71A	4c8bB-6cnhA: 22.0	4c8bB-6cnhA: 13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6cz4	PROTEIN-TYROSINE KINASE 6 (Homo sapiens)	no annotation	8	ALA A 217 ILE A 247 LEU A 248 THR A 264 HIS A 310 LEU A 319 ASP A 330 PHE A 331	FKY  A9001 (-3.3A) FKY  A9001 (-4.1A) FKY  A9001 (-4.2A) FKY  A9001 (-3.0A) FKY  A9001 (-3.9A) FKY  A9001 ( 4.9A) None FKY  A9001 (-3.9A)	0.92A	4c8bB-6cz4A: 25.6	4c8bB-6cz4A: 14.86