SIMILAR PATTERNS OF AMINO ACIDS FOR 4C49_D_HCYD1384_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a6c | TOBACCO RINGSPOTVIRUS CAPSID PROTEIN (Tobaccoringspot virus) |
PF03391(Nepo_coat)PF03688(Nepo_coat_C)PF03689(Nepo_coat_N) | 5 | SER A 45THR A 59ILE A 33PHE A 58HIS A 163 | None | 1.38A | 4c49D-1a6cA:undetectable | 4c49D-1a6cA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a7h | GAMMAS CRYSTALLIN (Bos taurus) |
PF00030(Crystall) | 5 | SER A 166VAL A 164GLN A 101ILE A 92HIS A 117 | None | 1.35A | 4c49D-1a7hA:0.0 | 4c49D-1a7hA:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dgj | ALDEHYDEOXIDOREDUCTASE (Desulfovibriodesulfuricans) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 5 | SER A 184ILE A 180ASN A 800SER A 179HIS A 95 | None | 1.41A | 4c49D-1dgjA:0.0 | 4c49D-1dgjA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1emy | MYOGLOBIN (Elephas maximus) |
PF00042(Globin) | 5 | GLN A 64PHE A 29ARG A 139ILE A 107HIS A 97 | CYN A 155 (-3.8A)CYN A 155 ( 4.9A)NoneHEM A 154 ( 3.9A)HEM A 154 (-3.5A) | 1.21A | 4c49D-1emyA:undetectable | 4c49D-1emyA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i78 | PROTEASE VII (Escherichiacoli) |
PF01278(Omptin) | 5 | SER A 137GLN A 105THR A 142SER A 76PHE A 141 | NoneNoneNoneBOG A 900 (-2.8A)None | 1.31A | 4c49D-1i78A:undetectable | 4c49D-1i78A:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1itu | RENAL DIPEPTIDASE (Homo sapiens) |
PF01244(Peptidase_M19) | 5 | THR A 149ARG A 229ASN A 231HIS A 152TRP A 162 | NoneNoneNoneCIL A 451 (-4.0A)None | 1.31A | 4c49D-1ituA:0.0 | 4c49D-1ituA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k38 | BETA-LACTAMASE OXA-2 (Salmonellaenterica) |
PF00905(Transpeptidase) | 5 | SER A 147GLN A 166THR A 68ASN A 143PHE A 69 | None | 1.15A | 4c49D-1k38A:0.0 | 4c49D-1k38A:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kkh | MEVALONATE KINASE (Methanocaldococcusjannaschii) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | SER A 129VAL A 128THR A 44ILE A 102PHE A 100 | None | 1.40A | 4c49D-1kkhA:0.0 | 4c49D-1kkhA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lhu | SEX HORMONE-BINDINGGLOBULIN (Homo sapiens) |
PF00054(Laminin_G_1) | 5 | SER A 111VAL A 112ILE A 78PHE A 67HIS A 81 | NoneNoneNoneEST A 301 (-4.0A)None | 1.11A | 4c49D-1lhuA:0.0 | 4c49D-1lhuA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1naa | CELLOBIOSEDEHYDROGENASE (Phanerochaetechrysosporium) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | SER A 654VAL A 653ILE A 606PHE A 524HIS A 526 | None | 1.31A | 4c49D-1naaA:0.0 | 4c49D-1naaA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1us2 | ENDO-BETA-1,4-XYLANASE (Cellvibriojaponicus) |
PF00331(Glyco_hydro_10)PF03426(CBM_15) | 5 | VAL A 486GLN A 466THR A 496ILE A 436PHE A 465 | NoneXYP A1609 (-2.7A)NoneNoneNone | 1.45A | 4c49D-1us2A:undetectable | 4c49D-1us2A:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vzv | VARICELLA-ZOSTERVIRUS PROTEASE (Humanalphaherpesvirus3) |
PF00716(Peptidase_S21) | 5 | SER A 120VAL A 119ILE A 48ASN A 49PHE A 73 | None | 1.44A | 4c49D-1vzvA:undetectable | 4c49D-1vzvA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1woq | INORGANICPOLYPHOSPHATE/ATP-GLUCOMANNOKINASE (Arthrobactersp. KM) |
PF00480(ROK) | 5 | SER A 184PHE A 218ILE A 147PHE A 206HIS A 208 | None | 1.22A | 4c49D-1woqA:undetectable | 4c49D-1woqA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xl8 | PEROXISOMALCARNITINEO-OCTANOYLTRANSFERASE (Mus musculus) |
PF00755(Carn_acyltransf) | 5 | SER A 399VAL A 576ILE A 596PHE A 600HIS A 601 | None | 1.23A | 4c49D-1xl8A:undetectable | 4c49D-1xl8A:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z5v | TUBULIN GAMMA-1CHAIN (Homo sapiens) |
PF00091(Tubulin)PF03953(Tubulin_C) | 5 | SER A 140VAL A 171GLN A 230ILE A 228SER A 226 | GSP A2466 (-3.1A)NoneNoneGSP A2466 (-4.5A)None | 1.30A | 4c49D-1z5vA:undetectable | 4c49D-1z5vA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a9f | PUTATIVE MALICENZYME((S)-MALATE:NAD+OXIDOREDUCTASE(DECARBOXYLATING)) (Streptococcuspyogenes) |
PF00390(malic)PF03949(Malic_M) | 5 | SER A 185VAL A 189PHE A 286ILE A 175PHE A 262 | None | 1.13A | 4c49D-2a9fA:undetectable | 4c49D-2a9fA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2akz | GAMMA ENOLASE (Homo sapiens) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | VAL A 349GLN A 408THR A 378ILE A 133PHE A 379 | None | 1.22A | 4c49D-2akzA:undetectable | 4c49D-2akzA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2au5 | CONSERVED DOMAINPROTEIN (Enterococcusfaecalis) |
PF11472(DUF3206) | 5 | VAL A 44GLN A 63THR A 29PHE A 28HIS A 32 | None | 1.43A | 4c49D-2au5A:undetectable | 4c49D-2au5A:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2av9 | THIOESTERASE (Pseudomonasaeruginosa) |
PF03061(4HBT) | 5 | VAL A 31GLN A 16THR A 42ILE A 82PHE A 39 | None | 1.25A | 4c49D-2av9A:undetectable | 4c49D-2av9A:18.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bm3 | SCAFFOLDING DOCKERINBINDING PROTEIN A (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 5 | VAL A 72ILE A 30ASN A 31SER A 7PHE A 36 | None | 1.41A | 4c49D-2bm3A:undetectable | 4c49D-2bm3A:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dvk | UPF0130 PROTEINAPE0816 (Aeropyrumpernix) |
PF02676(TYW3) | 5 | SER A 178VAL A 181ILE A 34ASN A 29HIS A 94 | None | 1.26A | 4c49D-2dvkA:undetectable | 4c49D-2dvkA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dwz | 26S PROTEASEREGULATORY SUBUNIT6B (Rattusnorvegicus) |
no annotation | 5 | SER B 371THR B 349PHE B 399ILE B 378PHE B 345 | None | 1.39A | 4c49D-2dwzB:undetectable | 4c49D-2dwzB:12.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e4u | METABOTROPICGLUTAMATE RECEPTOR 3 (Rattusnorvegicus) |
PF01094(ANF_receptor)PF07562(NCD3G) | 5 | SER A 214VAL A 213GLN A 197SER A 300PHE A 230 | None | 1.39A | 4c49D-2e4uA:undetectable | 4c49D-2e4uA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e7t | BASIC AGGLUTININ (Psophocarpustetragonolobus) |
PF00139(Lectin_legB) | 5 | SER A 201VAL A 57THR A 70PHE A 91ILE A 93 | None | 1.43A | 4c49D-2e7tA:undetectable | 4c49D-2e7tA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f3n | SH3 AND MULTIPLEANKYRIN REPEATDOMAINS 3 (Rattusnorvegicus) |
PF00536(SAM_1) | 5 | VAL A 49ARG A 55ILE A 58PHE A 26HIS A 35 | None | 1.34A | 4c49D-2f3nA:undetectable | 4c49D-2f3nA:10.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hv2 | HYPOTHETICAL PROTEIN (Enterococcusfaecalis) |
PF13527(Acetyltransf_9)PF13530(SCP2_2) | 5 | VAL A 214THR A 222ILE A 243PHE A 223HIS A 254 | None | 1.38A | 4c49D-2hv2A:undetectable | 4c49D-2hv2A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k8q | PROTEIN SHQ1 (Saccharomycescerevisiae) |
no annotation | 5 | SER A 69THR A 3PHE A 42ILE A 74ASN A 75 | None | 1.46A | 4c49D-2k8qA:undetectable | 4c49D-2k8qA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nvu | MALTOSE BINDINGPROTEIN/NEDD8-ACTIVATING ENZYME E1CATALYTIC SUBUNITCHIMERANEDD8-CONJUGATINGENZYME UBC12 (Homo sapiens) |
PF00179(UQ_con)PF00899(ThiF)PF08825(E2_bind)PF13416(SBP_bac_8) | 5 | SER B2396PHE C 80ILE C 125ASN C 126PHE C 60 | None | 1.39A | 4c49D-2nvuB:undetectable | 4c49D-2nvuB:18.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2omo | DUF176 (Nitrosomonaseuropaea) |
PF03992(ABM) | 5 | THR A 22ARG A 37ILE A 30ASN A 35SER A 29 | None | 1.43A | 4c49D-2omoA:undetectable | 4c49D-2omoA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ucz | UBIQUITINCONJUGATING ENZYME (Saccharomycescerevisiae) |
PF00179(UQ_con) | 5 | SER A 122VAL A 123THR A 74ILE A 41PHE A 73 | None | 1.47A | 4c49D-2uczA:undetectable | 4c49D-2uczA:18.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2v95 | CORTICOSTEROID-BINDING GLOBULIN (Rattusnorvegicus) |
PF00079(Serpin) | 7 | VAL A 17GLN A 224THR A 232PHE A 234ARG A 252ILE A 255PHE A 357 | HCY A1375 ( 4.8A)HCY A1375 (-3.5A)HCY A1375 ( 4.2A)HCY A1375 (-4.8A)HCY A1375 (-4.9A)NoneHCY A1375 ( 4.1A) | 0.69A | 4c49D-2v95A:37.5 | 4c49D-2v95A:61.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2v95 | CORTICOSTEROID-BINDING GLOBULIN (Rattusnorvegicus) |
PF00079(Serpin) | 7 | VAL A 17GLN A 224THR A 232PHE A 234ILE A 255PHE A 357TRP A 362 | HCY A1375 ( 4.8A)HCY A1375 (-3.5A)HCY A1375 ( 4.2A)HCY A1375 (-4.8A)NoneHCY A1375 ( 4.1A)HCY A1375 (-3.8A) | 0.57A | 4c49D-2v95A:37.5 | 4c49D-2v95A:61.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ve3 | PUTATIVE CYTOCHROMEP450 120 (Synechocystissp. PCC 6803) |
PF00067(p450) | 5 | SER A 429THR A 26PHE A 52SER A 83PHE A 29 | REA A1445 ( 4.3A)NoneNoneNoneREA A1445 (-4.6A) | 1.27A | 4c49D-2ve3A:undetectable | 4c49D-2ve3A:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vla | RESTRICTIONENDONUCLEASE R.BPUJI (Bacilluspumilus) |
PF11564(BpuJI_N) | 5 | SER A 156VAL A 230PHE A 138ILE A 141HIS A 209 | None | 1.44A | 4c49D-2vlaA:undetectable | 4c49D-2vlaA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsm | HEMAGGLUTININ-NEURAMINIDASE (Nipahhenipavirus) |
PF00423(HN) | 5 | SER A 411VAL A 367THR A 308ILE A 304PHE A 369 | None | 1.30A | 4c49D-2vsmA:undetectable | 4c49D-2vsmA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w3j | CARBOHYDRATE BINDINGMODULE (unculturedbacterium) |
PF16990(CBM_35) | 5 | VAL A 71GLN A 93PHE A 59ILE A 57PHE A 83 | None | 1.19A | 4c49D-2w3jA:undetectable | 4c49D-2w3jA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xf8 | D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE (Escherichiacoli) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | VAL A 172GLN A 220PHE A 221ILE A 158PHE A 225 | None | 1.40A | 4c49D-2xf8A:2.4 | 4c49D-2xf8A:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zxq | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Bifidobacteriumlongum) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 5 | VAL A1463PHE A1506ARG A1493ILE A1496ASN A1497 | None | 1.09A | 4c49D-2zxqA:undetectable | 4c49D-2zxqA:14.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a2b | SERINEPALMITOYLTRANSFERASE (Sphingobacteriummultivorum) |
PF00155(Aminotran_1_2) | 5 | SER A 214VAL A 217GLN A 35THR A 58SER A 51 | None | 1.43A | 4c49D-3a2bA:undetectable | 4c49D-3a2bA:24.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqx | BETA-1,3-GLUCAN-BINDING PROTEIN (Bombyx mori) |
PF15886(CBM39) | 5 | GLN A 88THR A 77PHE A 75ILE A 73PHE A 30 | None | 1.19A | 4c49D-3aqxA:undetectable | 4c49D-3aqxA:16.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bqw | PUTATIVE CAPSIDPROTEIN OF PROPHAGE (Escherichiacoli) |
PF03864(Phage_cap_E) | 5 | SER A 249VAL A 248THR A 287PHE A 35ILE A 208 | None | 1.43A | 4c49D-3bqwA:undetectable | 4c49D-3bqwA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e1k | GALACTOSE/LACTOSEMETABOLISMREGULATORY PROTEINGAL80 (Kluyveromyceslactis) |
PF01408(GFO_IDH_MocA) | 5 | VAL A 440PHE A 280ASN A 206PHE A 212HIS A 214 | None | 1.36A | 4c49D-3e1kA:undetectable | 4c49D-3e1kA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e1k | GALACTOSE/LACTOSEMETABOLISMREGULATORY PROTEINGAL80 (Kluyveromyceslactis) |
PF01408(GFO_IDH_MocA) | 5 | VAL A 440THR A 215PHE A 280ASN A 206HIS A 214 | None | 1.29A | 4c49D-3e1kA:undetectable | 4c49D-3e1kA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gs3 | SYMPLEKIN (Drosophilamelanogaster) |
PF11935(DUF3453) | 5 | SER A 147GLN A 161ILE A 105ASN A 106SER A 109 | None | 1.22A | 4c49D-3gs3A:undetectable | 4c49D-3gs3A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4s | FTSZ/TUBULIN-RELATEDPROTEIN (Bacillusthuringiensis) |
PF00091(Tubulin) | 5 | VAL A 325PHE A 291ILE A 288PHE A 334TRP A 365 | None | 1.40A | 4c49D-3j4sA:undetectable | 4c49D-3j4sA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j6d | PROTEIN PRGH (Salmonellaenterica) |
PF09480(PrgH) | 5 | ARG A 231ILE A 232ASN A 229PHE A 258HIS A 249 | None | 1.33A | 4c49D-3j6dA:undetectable | 4c49D-3j6dA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lma | STAGE V SPORULATIONPROTEIN AD (SPOVAD) (Bacilluslicheniformis) |
PF07451(SpoVAD) | 5 | SER A 19VAL A 17ILE A 117SER A 113PHE A 331 | None | 1.16A | 4c49D-3lmaA:undetectable | 4c49D-3lmaA:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lmk | METABOTROPICGLUTAMATE RECEPTOR 5 (Homo sapiens) |
PF01094(ANF_receptor) | 5 | SER A 215VAL A 214GLN A 198SER A 304PHE A 231 | None | 1.32A | 4c49D-3lmkA:undetectable | 4c49D-3lmkA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lrk | ALPHA-GALACTOSIDASE1 (Saccharomycescerevisiae) |
PF16499(Melibiase_2) | 5 | SER A 347GLN A 309ILE A 315SER A 311PHE A 464 | NoneGOL A7003 (-4.1A)NoneNoneNone | 1.44A | 4c49D-3lrkA:undetectable | 4c49D-3lrkA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pnz | PHOSPHOTRIESTERASEFAMILY PROTEIN (Listeriamonocytogenes) |
PF02126(PTE) | 5 | SER A 48VAL A 52GLN A 152ILE A 89HIS A 22 | NoneNoneNoneNone ZN A 333 ( 3.3A) | 1.46A | 4c49D-3pnzA:undetectable | 4c49D-3pnzA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3psf | TRANSCRIPTIONELONGATION FACTORSPT6 (Saccharomycescerevisiae) |
PF14635(HHH_7)PF14639(YqgF)PF14641(HTH_44)PF14878(DLD) | 5 | SER A 917THR A 731ILE A 904PHE A 729HIS A 727 | None | 1.30A | 4c49D-3psfA:undetectable | 4c49D-3psfA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3psi | TRANSCRIPTIONELONGATION FACTORSPT6 (Saccharomycescerevisiae) |
PF14635(HHH_7)PF14639(YqgF)PF14641(HTH_44)PF14878(DLD) | 5 | SER A 917THR A 731ILE A 904PHE A 729HIS A 727 | None | 1.39A | 4c49D-3psiA:undetectable | 4c49D-3psiA:15.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qnb | OXACILLINASE (Escherichiacoli) |
PF00905(Transpeptidase) | 5 | SER A 147GLN A 166THR A 68ASN A 143PHE A 69 | None | 1.21A | 4c49D-3qnbA:undetectable | 4c49D-3qnbA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3syb | GLYCINE-GLUTAMATEDIPEPTIDE PORIN OPDP (Pseudomonasaeruginosa) |
PF03573(OprD) | 5 | SER A 203GLN A 195THR A 164ARG A 159PHE A 167 | None | 1.29A | 4c49D-3sybA:undetectable | 4c49D-3sybA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6q | CD180 ANTIGEN (Mus musculus) |
PF13855(LRR_8) | 5 | SER A 535GLN A 493ILE A 486ASN A 485PHE A 516 | None | 1.34A | 4c49D-3t6qA:undetectable | 4c49D-3t6qA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6q | CD180 ANTIGEN (Mus musculus) |
PF13855(LRR_8) | 5 | THR A 517ILE A 486ASN A 485PHE A 516HIS A 514 | None | 1.36A | 4c49D-3t6qA:undetectable | 4c49D-3t6qA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u1k | POLYRIBONUCLEOTIDENUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL (Homo sapiens) |
PF00013(KH_1)PF01138(RNase_PH)PF03725(RNase_PH_C)PF03726(PNPase) | 5 | VAL A 313THR A 287ASN A 540PHE A 340HIS A 288 | None | 1.42A | 4c49D-3u1kA:undetectable | 4c49D-3u1kA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u44 | ATP-DEPENDENTHELICASE/DEOXYRIBONUCLEASE SUBUNIT B (Bacillussubtilis) |
PF12705(PDDEXK_1) | 5 | VAL B 544THR B 512PHE B 386ILE B 387SER B 390 | None | 1.46A | 4c49D-3u44B:undetectable | 4c49D-3u44B:16.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v9p | THYMIDYLATE KINASE (Burkholderiathailandensis) |
PF02223(Thymidylate_kin) | 5 | SER A 96VAL A 95GLN A 198PHE A 24HIS A 20 | NoneNoneGOL A 252 ( 4.5A)NoneNone | 1.37A | 4c49D-3v9pA:undetectable | 4c49D-3v9pA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a22 | FRUCTOSE-BISPHOSPHATE ALDOLASE (Mycobacteriumtuberculosis) |
PF01116(F_bP_aldolase) | 5 | SER A 31VAL A 34THR A 94PHE A 125PHE A 52 | NoneNone NA A1347 (-3.6A)NoneNone | 1.44A | 4c49D-4a22A:undetectable | 4c49D-4a22A:20.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 6 | GLN A 232THR A 240PHE A 242ASN A 264SER A 267PHE A 366 | None | 0.69A | 4c49D-4c41A:56.3 | 4c49D-4c41A:99.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 7 | VAL A 22GLN A 232THR A 240PHE A 242ILE A 263ASN A 264PHE A 366 | None | 0.71A | 4c49D-4c41A:56.3 | 4c49D-4c41A:99.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cdb | LISTERIOLYSIN O (Listeriamonocytogenes) |
PF01289(Thiol_cytolysin)PF17440(Thiol_cytolys_C) | 5 | VAL A 479PHE A 464ARG A 507ILE A 421SER A 466 | None | 1.14A | 4c49D-4cdbA:undetectable | 4c49D-4cdbA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dwq | TRNA-SPLICING LIGASERTCB (Pyrococcushorikoshii) |
PF01139(RtcB) | 5 | SER A 401GLN A 46THR A 43ARG A 350HIS A 67 | NoneNoneNoneNonePOP A 509 (-3.7A) | 1.45A | 4c49D-4dwqA:undetectable | 4c49D-4dwqA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4edp | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Clostridiumperfringens) |
PF13416(SBP_bac_8) | 5 | SER A 37VAL A 36GLN A 289THR A 292ILE A 264 | NoneNoneNoneACT A 403 (-3.5A)None | 1.28A | 4c49D-4edpA:undetectable | 4c49D-4edpA:24.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdj | N-ACETYLGALACTOSAMINE-6-SULFATASE (Homo sapiens) |
PF00884(Sulfatase)PF14707(Sulfatase_C) | 5 | VAL A 277PHE A 216ILE A 217PHE A 226HIS A 224 | None | 1.41A | 4c49D-4fdjA:undetectable | 4c49D-4fdjA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gn2 | OXACILLINASE (Pseudomonasaeruginosa) |
PF00905(Transpeptidase) | 5 | SER A 144GLN A 169THR A 64ASN A 140PHE A 65 | None | 1.24A | 4c49D-4gn2A:undetectable | 4c49D-4gn2A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hfs | UNCHARACTERIZEDPROTEIN YNCM (Bacillussubtilis) |
PF15493(YrpD) | 5 | GLN A 148THR A 150ILE A 218ASN A 242PHE A 68 | None | 1.39A | 4c49D-4hfsA:undetectable | 4c49D-4hfsA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kmh | SUPPRESSOR OF FUSEDHOMOLOG (Homo sapiens) |
PF05076(SUFU)PF12470(SUFU_C) | 5 | SER A 377GLN A 432ILE A 406PHE A 408HIS A 394 | None | 1.29A | 4c49D-4kmhA:undetectable | 4c49D-4kmhA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1y | SALIVARY NITROPHORIN (Cimexlectularius) |
no annotation | 5 | SER A 157THR A 11PHE A 278ILE A 255PHE A 167 | None | 1.35A | 4c49D-4l1yA:undetectable | 4c49D-4l1yA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m5p | NADPH DEHYDROGENASE (Scheffersomycesstipitis) |
PF00724(Oxidored_FMN) | 5 | SER A 309VAL A 308GLN A 200ILE A 241HIS A 258 | NA A 505 ( 4.3A)NoneNoneNoneNone | 1.45A | 4c49D-4m5pA:undetectable | 4c49D-4m5pA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mb5 | CHITINASE 60 (Moritellamarina) |
PF00704(Glyco_hydro_18)PF16403(DUF5011) | 5 | VAL A 270PHE A 337ARG A 306ILE A 338PHE A 295 | None | 1.41A | 4c49D-4mb5A:undetectable | 4c49D-4mb5A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mll | BETA-LACTAMASE OXA-1 (Escherichiacoli) |
PF00905(Transpeptidase) | 5 | SER A 147GLN A 172THR A 68ASN A 143PHE A 69 | None | 1.26A | 4c49D-4mllA:undetectable | 4c49D-4mllA:23.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pay | SIDC, INTERAPTIN (Legionellapneumophila) |
no annotation | 5 | SER A 348GLN A 395THR A 394ILE A 399PHE A 393 | None | 1.40A | 4c49D-4payA:0.0 | 4c49D-4payA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3l | MAJOR PILIN PROTEIN (Streptococcuspneumoniae) |
no annotation | 5 | SER A 337PHE A 305ILE A 244ASN A 371PHE A 261 | None | 1.45A | 4c49D-4s3lA:undetectable | 4c49D-4s3lA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w5z | CHITINASE 60 (Moritellamarina) |
PF00704(Glyco_hydro_18) | 5 | VAL A 270PHE A 337ARG A 306ILE A 338PHE A 295 | None | 1.39A | 4c49D-4w5zA:undetectable | 4c49D-4w5zA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xib | E3 UBIQUITIN-PROTEINLIGASE MIB1 (Homo sapiens) |
PF00569(ZZ)PF06701(MIB_HERC2) | 5 | VAL A 19ARG A 20ILE A 146PHE A 226HIS A 230 | None | 1.39A | 4c49D-4xibA:undetectable | 4c49D-4xibA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xr9 | CALS8 (Micromonosporaechinospora) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | SER A 394VAL A 420PHE A 444ARG A 419PHE A 446 | None | 1.46A | 4c49D-4xr9A:undetectable | 4c49D-4xr9A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3f | PHOSPHORIBULOKINASE/URIDINE KINASE (Methanospirillumhungatei) |
PF00485(PRK) | 5 | THR A 282PHE A 41ARG A 35ILE A 37SER A 307 | None | 1.38A | 4c49D-5b3fA:undetectable | 4c49D-5b3fA:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5but | KTR SYSTEM POTASSIUMUPTAKE PROTEIN B (Bacillussubtilis) |
PF02386(TrkH) | 5 | SER I 187PHE I 202ILE I 198ASN I 195PHE I 281 | None | 1.33A | 4c49D-5butI:undetectable | 4c49D-5butI:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ctm | BETA-LACTAMASE (Bacilluspumilus) |
PF00905(Transpeptidase) | 5 | SER A 181GLN A 200THR A 102ASN A 177PHE A 103 | None | 1.27A | 4c49D-5ctmA:undetectable | 4c49D-5ctmA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d79 | BERBERINE BRIDGEENZYME-LIKE PROTEIN (Arabidopsisthaliana) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | VAL A 104THR A 517ILE A 94SER A 211PHE A 519 | None | 1.35A | 4c49D-5d79A:undetectable | 4c49D-5d79A:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d9a | POLYMERASE BASICPROTEIN 2 (Influenza Cvirus) |
PF00604(Flu_PB2) | 5 | SER C 317VAL C 320THR C 295ARG C 267ILE C 266 | None | 1.39A | 4c49D-5d9aC:undetectable | 4c49D-5d9aC:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dz7 | POLYKETIDEBIOSYNTHESIS PROTEINPKSE (Bacillussubtilis) |
PF00698(Acyl_transf_1) | 5 | THR A 54PHE A 192ILE A 119SER A 189HIS A 53 | NoneGOL A 303 (-4.2A)NoneNoneNone | 1.22A | 4c49D-5dz7A:undetectable | 4c49D-5dz7A:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e2f | BETA-LACTAMASE YBXI (Bacillussubtilis) |
PF00905(Transpeptidase) | 5 | SER A 156GLN A 175THR A 77ASN A 152PHE A 78 | None | 1.34A | 4c49D-5e2fA:undetectable | 4c49D-5e2fA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fub | PROTEIN ARGININEMETHYLTRANSFERASE 2 (Danio rerio) |
PF13649(Methyltransf_25) | 5 | VAL A 187GLN A 105ILE A 107ASN A 110SER A 109 | None | 1.39A | 4c49D-5fubA:undetectable | 4c49D-5fubA:24.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gs2 | REPEBODY (Escherichiacoli) |
PF11921(DUF3439)PF12354(Internalin_N)PF13855(LRR_8) | 5 | VAL B 35PHE B 18ILE B 22ASN B 25PHE B 13 | None | 1.44A | 4c49D-5gs2B:undetectable | 4c49D-5gs2B:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5idu | ACYL-COADEHYDROGENASE DOMAINPROTEIN (Paraburkholderiaphymatum) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | SER A 127VAL A 126GLN A 233ILE A 110PHE A 177 | None | 1.28A | 4c49D-5iduA:undetectable | 4c49D-5iduA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5in2 | EXTRACELLULARSUPEROXIDE DISMUTASE[CU-ZN] (Onchocercavolvulus) |
PF00080(Sod_Cu) | 5 | SER A 15VAL A 35ILE A 18PHE A 45HIS A 48 | GOL A 201 (-3.4A)NoneNoneNone CU A 203 ( 3.2A) | 1.41A | 4c49D-5in2A:undetectable | 4c49D-5in2A:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jse | PHIAB6 TAILSPIKE (unidentifiedphage) |
PF12708(Pectate_lyase_3) | 5 | VAL A 302PHE A 310ILE A 297PHE A 307HIS A 262 | None | 1.32A | 4c49D-5jseA:undetectable | 4c49D-5jseA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k10 | ISOCITRATEDEHYDROGENASE [NADP]CYTOPLASMIC (Homo sapiens) |
PF00180(Iso_dh) | 5 | THR A 325PHE A 395ARG A 20ILE A 21HIS A 315 | NoneNoneNoneNoneNDP A 501 (-4.7A) | 1.46A | 4c49D-5k10A:undetectable | 4c49D-5k10A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lxv | SCAFFOLDIN C (Ruminococcusflavefaciens) |
PF00963(Cohesin) | 5 | SER A 79VAL A 78GLN A 19ILE A 50ASN A 82 | None | 1.41A | 4c49D-5lxvA:undetectable | 4c49D-5lxvA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nug | CYTOPLASMIC DYNEIN 1HEAVY CHAIN 1 (Homo sapiens) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 5 | VAL A2592ILE A2666ASN A2667PHE A2727HIS A2725 | None | 1.27A | 4c49D-5nugA:undetectable | 4c49D-5nugA:5.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o8m | YTHDOMAIN-CONTAININGPROTEIN MMI1 (Schizosaccharomycespombe) |
no annotation | 5 | VAL A 409ILE A 382SER A 378HIS A 426TRP A 372 | NoneNoneGOL A 502 (-2.8A)NoneNone | 1.27A | 4c49D-5o8mA:undetectable | 4c49D-5o8mA:13.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u03 | CTP SYNTHASE 1 (Homo sapiens) |
PF00117(GATase)PF06418(CTP_synth_N) | 5 | SER A 22VAL A 23GLN A 240ILE A 178PHE A 266 | None | 1.44A | 4c49D-5u03A:undetectable | 4c49D-5u03A:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wde | KINESIN-LIKE PROTEINKIFC3 (Homo sapiens) |
PF00225(Kinesin) | 5 | SER A 746VAL A 452ILE A 479SER A 489PHE A 471 | NoneNoneNoneUNX A 920 ( 4.4A)None | 1.34A | 4c49D-5wdeA:undetectable | 4c49D-5wdeA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yww | NUCLEOTIDE BINDINGPROTEIN PINC (Sulfolobusislandicus) |
no annotation | 5 | SER A 168VAL A 171ARG A 172ILE A 209SER A 197 | None | 1.30A | 4c49D-5ywwA:undetectable | 4c49D-5ywwA:12.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5znn | SORTILIN (Mus musculus) |
no annotation | 5 | SER A 478VAL A 486ILE A 413SER A 415HIS A 461 | None | 1.40A | 4c49D-5znnA:undetectable | 4c49D-5znnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bqw | BACTERIAL ACTIN ALFA (Bacillussubtilis) |
no annotation | 5 | SER A 189VAL A 176ILE A 215ASN A 214PHE A 208 | None | 1.36A | 4c49D-6bqwA:undetectable | 4c49D-6bqwA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c0f | PROTEASOME-INTERACTING PROTEIN CIC1 (Saccharomycescerevisiae) |
no annotation | 5 | SER K 105GLN K 143THR K 223ILE K 149SER K 146 | None | 1.37A | 4c49D-6c0fK:undetectable | 4c49D-6c0fK:13.98 |