SIMILAR PATTERNS OF AMINO ACIDS FOR 4C49_A_HCYA1384
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1agx | GLUTAMINASE-ASPARAGINASE (Acinetobacterglutaminasificans) |
PF00710(Asparaginase) | 5 | ALA A 135SER A 134THR A 9ILE A 13HIS A 90 | None | 1.22A | 4c49A-1agxA:0.0 | 4c49A-1agxA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1at3 | HERPES SIMPLEX VIRUSTYPE II PROTEASE (Humanalphaherpesvirus2) |
PF00716(Peptidase_S21) | 5 | SER A 129VAL A 128ILE A 57ASN A 58PHE A 82 | DFP A 300 ( 1.5A)NoneNoneNoneNone | 1.30A | 4c49A-1at3A:undetectable | 4c49A-1at3A:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i74 | PROBABLEMANGANESE-DEPENDENTINORGANICPYROPHOSPHATASE (Streptococcusmutans) |
PF01368(DHH)PF02833(DHHA2) | 5 | ALA A 68VAL A 71GLN A 9ILE A 86PHE A 6 | None | 1.11A | 4c49A-1i74A:undetectable | 4c49A-1i74A:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j3n | 3-OXOACYL-(ACYL-CARRIER PROTEIN)SYNTHASE II (Thermusthermophilus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | ALA A 165GLN A 26THR A 332PHE A 22ILE A 349 | None | 1.26A | 4c49A-1j3nA:0.0 | 4c49A-1j3nA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k20 | MANGANESE-DEPENDENTINORGANICPYROPHOSPHATASE (Streptococcusgordonii) |
PF01368(DHH)PF02833(DHHA2) | 5 | ALA A 70VAL A 73GLN A 10ILE A 88PHE A 7 | None | 1.23A | 4c49A-1k20A:undetectable | 4c49A-1k20A:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1li7 | CYSTEINYL-TRNASYNTHETASE (Escherichiacoli) |
PF01406(tRNA-synt_1e)PF09190(DALR_2) | 5 | ALA A 46VAL A 50THR A 7ILE A 223HIS A 256 | None | 1.16A | 4c49A-1li7A:0.0 | 4c49A-1li7A:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ljy | MGP-40 (Capra hircus) |
PF00704(Glyco_hydro_18) | 5 | SER A 181VAL A 157GLN A 172ILE A 170HIS A 176 | None | 1.16A | 4c49A-1ljyA:0.0 | 4c49A-1ljyA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m32 | 2-AMINOETHYLPHOSPHONATE-PYRUVATEAMINOTRANSFERASE (Salmonellaenterica) |
PF00266(Aminotran_5) | 5 | ALA A 280SER A 277PHE A 338ILE A 340PHE A 303 | None | 1.19A | 4c49A-1m32A:0.0 | 4c49A-1m32A:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n8y | PROTOONCOPROTEIN (Rattusnorvegicus) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 5 | ALA C 393SER C 392GLN C 375ILE C 335SER C 337 | None | 1.22A | 4c49A-1n8yC:0.0 | 4c49A-1n8yC:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p1v | SUPEROXIDE DISMUTASE[CU-ZN] (Homo sapiens) |
PF00080(Sod_Cu) | 5 | ALA A 95SER A 34VAL A 97PHE A 45HIS A 120 | NoneNoneNoneNone ZN A 201 ( 3.2A) | 1.11A | 4c49A-1p1vA:undetectable | 4c49A-1p1vA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q9j | POLYKETIDE SYNTHASEASSOCIATED PROTEIN 5 (Mycobacteriumtuberculosis) |
PF00668(Condensation)PF16911(PapA_C) | 5 | ALA A 288SER A 289VAL A 263SER A 13PHE A 327 | None | 1.20A | 4c49A-1q9jA:undetectable | 4c49A-1q9jA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r5m | SIR4-INTERACTINGPROTEIN SIF2 (Saccharomycescerevisiae) |
PF00400(WD40)PF12894(ANAPC4_WD40) | 5 | ALA A 407VAL A 415ILE A 385SER A 393PHE A 397 | None | 1.14A | 4c49A-1r5mA:undetectable | 4c49A-1r5mA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sxz | PROTEIN (CU-ZNSUPEROXIDEDISMUTASE) (Bos taurus) |
PF00080(Sod_Cu) | 5 | ALA A 93SER A 32VAL A 95PHE A 43HIS A 118 | NoneNoneNoneNone CU A 152 (-3.2A) | 1.25A | 4c49A-1sxzA:undetectable | 4c49A-1sxzA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u08 | HYPOTHETICALAMINOTRANSFERASEYBDL (Escherichiacoli) |
PF00155(Aminotran_1_2) | 5 | ALA A 103VAL A 96THR A 237ILE A 76PHE A 234 | None | 1.25A | 4c49A-1u08A:undetectable | 4c49A-1u08A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uai | POLYGULURONATE LYASE (Corynebacteriumsp.) |
PF08787(Alginate_lyase2) | 5 | ALA A 86SER A 87PHE A 162ILE A 118PHE A 190 | None | 1.17A | 4c49A-1uaiA:undetectable | 4c49A-1uaiA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uf2 | CORE PROTEIN P3 (Rice dwarfvirus) |
PF09231(RDV-p3) | 5 | SER A 800ILE A 847ASN A 783SER A 848PHE A 862 | None | 1.30A | 4c49A-1uf2A:undetectable | 4c49A-1uf2A:18.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vqr | HYPOTHETICAL PROTEINCJ0248 (Campylobacterjejuni) |
PF08668(HDOD) | 5 | ALA A 125SER A 136VAL A 140ILE A 74ASN A 75 | None | 1.19A | 4c49A-1vqrA:undetectable | 4c49A-1vqrA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vzv | VARICELLA-ZOSTERVIRUS PROTEASE (Humanalphaherpesvirus3) |
PF00716(Peptidase_S21) | 5 | SER A 120VAL A 119ILE A 48ASN A 49PHE A 73 | None | 1.25A | 4c49A-1vzvA:undetectable | 4c49A-1vzvA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1woq | INORGANICPOLYPHOSPHATE/ATP-GLUCOMANNOKINASE (Arthrobactersp. KM) |
PF00480(ROK) | 5 | ALA A 183SER A 184PHE A 218ILE A 147PHE A 206 | None | 1.07A | 4c49A-1woqA:undetectable | 4c49A-1woqA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y56 | SARCOSINE OXIDASE (Pyrococcushorikoshii) |
PF01266(DAO) | 5 | ALA B 250SER B 244VAL B 242THR B 230ILE B 292 | None | 1.16A | 4c49A-1y56B:undetectable | 4c49A-1y56B:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yj8 | GLYCEROL-3-PHOSPHATEDEHYDROGENASE (Plasmodiumfalciparum) |
PF01210(NAD_Gly3P_dh_N)PF07479(NAD_Gly3P_dh_C) | 5 | ALA A 35SER A 34ILE A 108SER A 139PHE A 203 | None | 1.21A | 4c49A-1yj8A:undetectable | 4c49A-1yj8A:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z5v | TUBULIN GAMMA-1CHAIN (Homo sapiens) |
PF00091(Tubulin)PF03953(Tubulin_C) | 5 | SER A 140VAL A 171GLN A 230ILE A 228SER A 226 | GSP A2466 (-3.1A)NoneNoneGSP A2466 (-4.5A)None | 1.28A | 4c49A-1z5vA:undetectable | 4c49A-1z5vA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a2a | DEATH-ASSOCIATEDPROTEIN KINASE 2 (Homo sapiens) |
PF00069(Pkinase) | 5 | ALA A 25SER A 21VAL A 27ILE A 160ASN A 144 | NoneNoneNoneGOL A3001 ( 3.9A)None | 0.98A | 4c49A-2a2aA:undetectable | 4c49A-2a2aA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a9f | PUTATIVE MALICENZYME((S)-MALATE:NAD+OXIDOREDUCTASE(DECARBOXYLATING)) (Streptococcuspyogenes) |
PF00390(malic)PF03949(Malic_M) | 5 | SER A 185VAL A 189PHE A 286ILE A 175PHE A 262 | None | 1.25A | 4c49A-2a9fA:undetectable | 4c49A-2a9fA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aeu | HYPOTHETICAL PROTEINMJ0158 (Methanocaldococcusjannaschii) |
PF03841(SelA) | 5 | ALA A 180SER A 205VAL A 203SER A 117PHE A 176 | SO4 A1001 ( 4.6A)SO4 A1001 (-2.6A)NoneNoneNone | 1.26A | 4c49A-2aeuA:undetectable | 4c49A-2aeuA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bo9 | HUMAN LATEXIN (Homo sapiens) |
PF06907(Latexin) | 5 | VAL B 58PHE B 89ILE B 21ASN B 22PHE B 91 | None | 1.23A | 4c49A-2bo9B:undetectable | 4c49A-2bo9B:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cnd | NADH-DEPENDENTNITRATE REDUCTASE (Zea mays) |
PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 5 | ALA A 174VAL A 172PHE A 267ASN A 255SER A 253 | None | 1.21A | 4c49A-2cndA:undetectable | 4c49A-2cndA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d6l | LECTIN, GALACTOSEBINDING, SOLUBLE 9 (Mus musculus) |
PF00337(Gal-bind_lectin) | 5 | SER X 136VAL X 46GLN X 7PHE X 146ILE X 144 | None | 1.19A | 4c49A-2d6lX:undetectable | 4c49A-2d6lX:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ijd | PICORNAIN 3C,RNA-DIRECTED RNAPOLYMERASE (Enterovirus C) |
PF00548(Peptidase_C3)PF00680(RdRP_1) | 5 | ALA 1 224THR 1 235ILE 1 241SER 1 243PHE 1 237 | None | 1.17A | 4c49A-2ijd1:undetectable | 4c49A-2ijd1:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jdx | PROTEIN(L-ARGININE:GLYCINEAMIDINOTRANSFERASE) (Homo sapiens) |
no annotation | 5 | ALA A 261THR A 307PHE A 296ILE A 294PHE A 308 | None | 1.16A | 4c49A-2jdxA:undetectable | 4c49A-2jdxA:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nn3 | CASPASE-1 (Spodopterafrugiperda) |
PF00656(Peptidase_C14) | 5 | VAL C 131THR C 159ILE C 115PHE C 158TRP C 155 | None | 1.28A | 4c49A-2nn3C:undetectable | 4c49A-2nn3C:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p9b | POSSIBLE PROLIDASE (Bifidobacteriumlongum) |
PF01979(Amidohydro_1) | 5 | ALA A 259VAL A 261THR A 207ILE A 264SER A 268 | None | 1.21A | 4c49A-2p9bA:undetectable | 4c49A-2p9bA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qzu | PUTATIVE SULFATASEYIDJ (Bacteroidesfragilis) |
PF00884(Sulfatase) | 5 | ALA A 205SER A 206THR A 306PHE A 222ASN A 213 | None | 1.23A | 4c49A-2qzuA:undetectable | 4c49A-2qzuA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r0b | SERINE/THREONINE/TYROSINE-INTERACTINGPROTEIN (Homo sapiens) |
PF00782(DSPc) | 5 | THR A 102PHE A 130ILE A 95ASN A 94PHE A 99 | None | 1.27A | 4c49A-2r0bA:undetectable | 4c49A-2r0bA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uxt | PROTEIN SUFI (Escherichiacoli) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | ALA A 378VAL A 376PHE A 396ILE A 356PHE A 448 | None | 1.30A | 4c49A-2uxtA:undetectable | 4c49A-2uxtA:20.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2v95 | CORTICOSTEROID-BINDING GLOBULIN (Rattusnorvegicus) |
PF00079(Serpin) | 8 | ALA A 13VAL A 17GLN A 224THR A 232PHE A 234ILE A 255PHE A 357TRP A 362 | HCY A1375 (-3.6A)HCY A1375 ( 4.8A)HCY A1375 (-3.5A)HCY A1375 ( 4.2A)HCY A1375 (-4.8A)NoneHCY A1375 ( 4.1A)HCY A1375 (-3.8A) | 0.68A | 4c49A-2v95A:39.0 | 4c49A-2v95A:61.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v9k | UNCHARACTERIZEDPROTEIN FLJ32312 (Homo sapiens) |
no annotation | 5 | ALA A 416SER A 415THR A 497ILE A 461PHE A 489 | None | 1.15A | 4c49A-2v9kA:undetectable | 4c49A-2v9kA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w4k | DEATH-ASSOCIATEDPROTEIN KINASE 1 (Homo sapiens) |
PF00069(Pkinase) | 5 | ALA A 25SER A 21VAL A 27ILE A 160ASN A 144 | ADP A1303 ( 3.7A)NoneADP A1303 (-4.0A)ADP A1303 ( 4.1A) MG A1304 ( 4.2A) | 1.08A | 4c49A-2w4kA:undetectable | 4c49A-2w4kA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xax | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1SUBUNIT ALPHA (Escherichiacoli) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 5 | THR A 276PHE A 281ILE A 237ASN A 238PHE A 274 | None | 1.23A | 4c49A-2xaxA:undetectable | 4c49A-2xaxA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yab | DEATH-ASSOCIATEDPROTEIN KINASE 2 (Mus musculus) |
PF00069(Pkinase) | 5 | ALA A 25SER A 21VAL A 27ILE A 160ASN A 144 | AMP A1302 (-3.6A)NoneAMP A1302 (-4.2A)AMP A1302 (-4.0A)AMP A1302 ( 4.8A) | 1.12A | 4c49A-2yabA:undetectable | 4c49A-2yabA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yky | BETA-TRANSAMINASE (Mesorhizobiumsp. LUK) |
PF00202(Aminotran_3) | 5 | SER A 287GLN A 331THR A 330ILE A 101HIS A 326 | None | 1.02A | 4c49A-2ykyA:undetectable | 4c49A-2ykyA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dgz | THIOREDOXINREDUCTASE 2 (Mus musculus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 452SER A 453VAL A 457THR A 441PHE A 444 | None | 1.28A | 4c49A-3dgzA:undetectable | 4c49A-3dgzA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dhu | ALPHA-AMYLASE (Lactobacillusplantarum) |
PF00128(Alpha-amylase) | 5 | VAL A 165PHE A 28ILE A 51ASN A 52PHE A 85 | None | 1.22A | 4c49A-3dhuA:undetectable | 4c49A-3dhuA:24.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dui | BETA-GALACTOSIDE-BINDING LECTIN (Gallus gallus) |
PF00337(Gal-bind_lectin) | 5 | SER A 107VAL A 99ILE A 59PHE A 46HIS A 45 | None | 1.08A | 4c49A-3duiA:undetectable | 4c49A-3duiA:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f11 | IRON TRANSPORTPROTEIN (Synechocystissp. PCC 6803) |
PF13343(SBP_bac_6) | 5 | ALA A 286VAL A 98PHE A 140ILE A 296SER A 121 | None | 1.30A | 4c49A-3f11A:undetectable | 4c49A-3f11A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f9r | PHOSPHOMANNOMUTASE (Trypanosomabrucei) |
PF03332(PMM) | 5 | VAL A 239THR A 42PHE A 63ILE A 30PHE A 9 | None | 1.16A | 4c49A-3f9rA:undetectable | 4c49A-3f9rA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hj7 | TRNA(ILE)-LYSIDINESYNTHASE (Geobacilluskaustophilus) |
PF11734(TilS_C) | 5 | ALA A 429VAL A 380PHE A 359ILE A 455SER A 357 | None | 1.31A | 4c49A-3hj7A:undetectable | 4c49A-3hj7A:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ibg | ATPASE, SUBUNIT OFTHE GET COMPLEX (Aspergillusfumigatus) |
PF02374(ArsA_ATPase) | 5 | ALA A 91SER A 90VAL A 83THR A 41ILE A 48 | NoneNoneNoneADP A 349 (-3.6A)None | 1.26A | 4c49A-3ibgA:undetectable | 4c49A-3ibgA:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3isr | TRANSGLUTAMINASE-LIKE ENZYMES, PUTATIVECYSTEINE PROTEASE (Cytophagahutchinsonii) |
PF01841(Transglut_core) | 5 | ALA A 242ILE A 9SER A 7PHE A 21HIS A 24 | None | 1.28A | 4c49A-3isrA:undetectable | 4c49A-3isrA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3llr | DNA(CYTOSINE-5)-METHYLTRANSFERASE 3A (Homo sapiens) |
PF00855(PWWP) | 6 | ALA A 102SER A 103PHE A 80ILE A 133ASN A 129PHE A 76 | None | 1.49A | 4c49A-3llrA:undetectable | 4c49A-3llrA:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm6 | STAGE V SPORULATIONPROTEIN AD (Bacillussubtilis) |
PF07451(SpoVAD) | 5 | ALA A 283SER A 282VAL A 285THR A 40PHE A 37 | None | 1.11A | 4c49A-3lm6A:undetectable | 4c49A-3lm6A:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lrh | ANTI-HUNTINGTIN VLDOMAIN (Homo sapiens) |
PF07686(V-set) | 5 | ALA A 12SER A 11VAL A 107ILE A 20SER A 73 | None | 1.25A | 4c49A-3lrhA:undetectable | 4c49A-3lrhA:15.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lw2 | PLASMINOGENACTIVATOR INHIBITOR1 (Mus musculus) |
PF00079(Serpin) | 5 | ALA A 335SER A 336VAL A 324ASN A 167SER A 40 | None | 1.07A | 4c49A-3lw2A:43.0 | 4c49A-3lw2A:28.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ml6 | CHIMERIC COMPLEXBETWEEN PROTEINDISHEVLLED2 HOMOLOGDVL-2 AND CLATHRINADAPTOR AP-2 COMPLEXSUBUNIT MU (Mus musculus;Rattusnorvegicus) |
PF00610(DEP)PF00928(Adap_comp_sub) | 5 | ALA A1368SER A1367VAL A1303ILE A1386SER A1387 | None | 1.27A | 4c49A-3ml6A:undetectable | 4c49A-3ml6A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3olz | GLUTAMATE RECEPTOR,IONOTROPIC KAINATE 3 (Rattusnorvegicus) |
PF01094(ANF_receptor) | 5 | ALA A 144VAL A 146THR A 249PHE A 251ILE A 132 | None | 1.14A | 4c49A-3olzA:undetectable | 4c49A-3olzA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oov | METHYL-ACCEPTINGCHEMOTAXIS PROTEIN,PUTATIVE (Geobactersulfurreducens) |
PF13185(GAF_2) | 5 | SER A 47VAL A 62THR A 54ILE A 104PHE A 57 | None | 1.31A | 4c49A-3oovA:undetectable | 4c49A-3oovA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3poy | NEUREXIN-1-ALPHA (Bos taurus) |
PF00008(EGF)PF02210(Laminin_G_2) | 5 | SER A 528VAL A 601THR A 533ILE A 540PHE A 531 | None | 1.28A | 4c49A-3poyA:undetectable | 4c49A-3poyA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pr2 | TRYPTOPHAN SYNTHASEBETA CHAIN (Salmonellaenterica) |
PF00291(PALP) | 5 | ALA B 335SER B 352GLN B 370THR B 71ILE B 228 | None | 1.28A | 4c49A-3pr2B:undetectable | 4c49A-3pr2B:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u97 | RIBONUCLEASE TOXINBRNT (Brucellaabortus) |
PF04365(BrnT_toxin) | 5 | SER A 70VAL A 56PHE A 26ILE A 3PHE A 29 | None | 1.31A | 4c49A-3u97A:undetectable | 4c49A-3u97A:13.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wg1 | GALACTOSIDE-BINDINGLECTIN (Agrocybeaegerita) |
PF00337(Gal-bind_lectin) | 5 | SER A 34ILE A 147ASN A 37SER A 39PHE A 96 | None | 1.20A | 4c49A-3wg1A:undetectable | 4c49A-3wg1A:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zpx | LIPASE (Ustilago maydis) |
PF03583(LIP) | 5 | ALA A 236SER A 239VAL A 238SER A 288PHE A 222 | None | 1.28A | 4c49A-3zpxA:undetectable | 4c49A-3zpxA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aca | TRANSLATIONELONGATION FACTORSELB (Methanococcusmaripaludis) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2) | 5 | ALA A 75SER A 78VAL A 77ILE A 307HIS A 69 | None | 1.22A | 4c49A-4acaA:undetectable | 4c49A-4acaA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4axv | MPAA (Vibriocampbellii) |
PF04952(AstE_AspA) | 5 | SER A 59THR A 207ILE A 43PHE A 155HIS A 156 | NoneNoneNoneNone ZN A 301 (-3.2A) | 1.31A | 4c49A-4axvA:undetectable | 4c49A-4axvA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b67 | L-ORNITHINE N5MONOOXYGENASE (Aspergillusfumigatus) |
PF13434(K_oxygenase) | 5 | SER A 417VAL A 419THR A 203ILE A 451PHE A 186 | None | 0.92A | 4c49A-4b67A:undetectable | 4c49A-4b67A:21.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 5 | ALA A 18SER A 19VAL A 22GLN A 232PHE A 366 | None | 0.74A | 4c49A-4c41A:58.9 | 4c49A-4c41A:99.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 7 | ALA A 18VAL A 22GLN A 232PHE A 242ILE A 263PHE A 366HIS A 368 | None | 1.01A | 4c49A-4c41A:58.9 | 4c49A-4c41A:99.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 8 | ALA A 18VAL A 22GLN A 232THR A 240PHE A 242ILE A 263ASN A 264PHE A 366 | None | 0.70A | 4c49A-4c41A:58.9 | 4c49A-4c41A:99.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 5 | GLN A 232THR A 240PHE A 242ASN A 264SER A 267 | None | 0.96A | 4c49A-4c41A:58.9 | 4c49A-4c41A:99.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ccw | CARBOXYL ESTERASE NP (Bacillussubtilis) |
PF12697(Abhydrolase_6) | 5 | ALA A 150SER A 149VAL A 147PHE A 139HIS A 135 | None | 1.25A | 4c49A-4ccwA:undetectable | 4c49A-4ccwA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cnt | DIHYDROPYRIMIDINASE-LIKE 3 (Homo sapiens) |
PF01979(Amidohydro_1) | 5 | SER A 385GLN A 196THR A 253ILE A 391HIS A 73 | None | 1.25A | 4c49A-4cntA:undetectable | 4c49A-4cntA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e93 | TYROSINE-PROTEINKINASE FES/FPS (Homo sapiens) |
PF00017(SH2)PF07714(Pkinase_Tyr) | 5 | SER A 494VAL A 495GLN A 535THR A 533HIS A 529 | None | 1.18A | 4c49A-4e93A:undetectable | 4c49A-4e93A:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fq7 | MALEATE CIS-TRANSISOMERASE (Pseudomonasputida) |
no annotation | 5 | ALA A 223SER A 222VAL A 196ILE A 125HIS A 94 | None | 1.06A | 4c49A-4fq7A:undetectable | 4c49A-4fq7A:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gaf | EBI-005 (Homo sapiens) |
PF00340(IL1) | 5 | ALA A 58SER A 44PHE A 146ILE A 10PHE A 111 | None | 1.11A | 4c49A-4gafA:undetectable | 4c49A-4gafA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4go4 | PUTATIVEGAMMA-HYDROXYMUCONICSEMIALDEHYDEDEHYDROGENASE (Pseudomonas sp.WBC-3) |
PF00171(Aldedh) | 5 | ALA A 371VAL A 369ILE A 336SER A 334PHE A 386 | None | 1.29A | 4c49A-4go4A:undetectable | 4c49A-4go4A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lrs | 4-HYDROXY-2-OXOVALERATE ALDOLASE (Thermomonosporacurvata) |
PF00682(HMGL-like)PF07836(DmpG_comm) | 5 | ALA A 230SER A 18THR A 249PHE A 250ILE A 227 | None | 1.30A | 4c49A-4lrsA:undetectable | 4c49A-4lrsA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ofw | PROTEIN DJ-1 HOMOLOGD (Arabidopsisthaliana) |
PF01965(DJ-1_PfpI) | 5 | ALA A 188VAL A 186ILE A 32PHE A 388HIS A 389 | None | 1.25A | 4c49A-4ofwA:undetectable | 4c49A-4ofwA:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pfb | C4-DICARBOXYLATE-BINDING PROTEIN (Fusobacteriumnucleatum) |
PF03480(DctP) | 5 | VAL A 29GLN A 251ILE A 50ASN A 51SER A 54 | None | 1.21A | 4c49A-4pfbA:undetectable | 4c49A-4pfbA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pln | NEOGENIN (Mus musculus) |
PF00041(fn3) | 5 | ALA C 925VAL C 908GLN C 876ILE C 887SER C 878 | None | 1.22A | 4c49A-4plnC:undetectable | 4c49A-4plnC:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qyr | AT-LESS POLYKETIDESYNTHASE (Streptomycesplatensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ALA A2779GLN A2568THR A2564ILE A2889PHE A2565 | None | 1.25A | 4c49A-4qyrA:undetectable | 4c49A-4qyrA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xvx | ACYL-[ACYL-CARRIER-PROTEIN]DEHYDROGENASE MBTN (Mycobacteriumtuberculosis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | ALA A 17VAL A 22PHE A 35ILE A 79HIS A 86 | None | 1.30A | 4c49A-4xvxA:undetectable | 4c49A-4xvxA:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z61 | PHYTOSULFOKINERECEPTOR 1 (Daucus carota) |
PF00560(LRR_1)PF13855(LRR_8) | 5 | ALA A 127SER A 129ILE A 154SER A 176PHE A 150 | None | 1.22A | 4c49A-4z61A:undetectable | 4c49A-4z61A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zo6 | LIN1840 PROTEIN (Listeriainnocua) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 5 | ALA A 188VAL A 133ILE A 268PHE A 135HIS A 192 | NoneNoneNoneBGC A 802 (-4.3A)BGC A 802 (-4.0A) | 1.16A | 4c49A-4zo6A:undetectable | 4c49A-4zo6A:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zoy | SQT1 (Chaetomiumthermophilum) |
PF00400(WD40) | 5 | ALA A 420SER A 401VAL A 426GLN A 512PHE A 510 | None | 1.26A | 4c49A-4zoyA:undetectable | 4c49A-4zoyA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aul | PHOSPHATIDYLINOSITOL3-KINASE REGULATORYSUBUNIT ALPHA (Homo sapiens) |
PF00017(SH2) | 5 | SER A 660VAL A 661GLN A 705THR A 701HIS A 697 | None | 1.21A | 4c49A-5aulA:undetectable | 4c49A-5aulA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b5z | PTLCIB4 H88A MUTANT (Phaeodactylumtricornutum) |
no annotation | 5 | ALA A 23SER A 26VAL A 25GLN A 232ILE A 98 | None | 1.24A | 4c49A-5b5zA:undetectable | 4c49A-5b5zA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c6w | PROTEINIGHV1-69-2,IG LAMBDACHAIN V-II REGIONNIG-84 (Homo sapiens) |
PF07686(V-set) | 5 | ALA H1012SER H1011VAL H1107ILE H1020SER H1074 | None | 1.07A | 4c49A-5c6wH:undetectable | 4c49A-5c6wH:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d04 | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATEALDOLASE (Neisseriameningitidis) |
PF00793(DAHP_synth_1) | 5 | ALA C 251VAL C 248ILE C 266ASN C 272HIS C 232 | None | 1.29A | 4c49A-5d04C:undetectable | 4c49A-5d04C:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eqv | BIFUNCTIONAL2',3'-CYCLICNUCLEOTIDE2'-PHOSPHODIESTERASE/3'-NUCLEOTIDASEPERIPLASMICPRECURSOR PROTEIN (Yersinia pestis) |
PF00149(Metallophos) | 5 | VAL A 150ILE A 122ASN A 121PHE A 127HIS A 125 | NoneNoneNoneNonePO4 A 405 ( 3.9A) | 1.20A | 4c49A-5eqvA:undetectable | 4c49A-5eqvA:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5erd | DESMOGLEIN-2 (Homo sapiens) |
PF00028(Cadherin) | 5 | SER A 148GLN A 112PHE A 115ILE A 132PHE A 110 | None | 1.18A | 4c49A-5erdA:undetectable | 4c49A-5erdA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fse | UREASE SUBUNIT ALPHA (Sporosarcinapasteurii) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 5 | SER C 496THR C 136ILE C 420PHE C 158HIS C 272 | None | 1.26A | 4c49A-5fseC:undetectable | 4c49A-5fseC:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5idu | ACYL-COADEHYDROGENASE DOMAINPROTEIN (Paraburkholderiaphymatum) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | SER A 127VAL A 126GLN A 233ILE A 110PHE A 177 | None | 1.30A | 4c49A-5iduA:undetectable | 4c49A-5iduA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j0g | OXIDOREDUCTASE,SUPEROXIDE DISMUTASE[CU-ZN] (Homo sapiens) |
PF00080(Sod_Cu) | 5 | ALA A 83SER A 52VAL A 85PHE A 63HIS A 108 | None | 1.31A | 4c49A-5j0gA:undetectable | 4c49A-5j0gA:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j5j | DESMOCOLLIN-2,DESMOGLEIN-2 (Homo sapiens) |
PF00028(Cadherin) | 5 | SER A 146GLN A 110PHE A 113ILE A 130PHE A 108 | None | 1.18A | 4c49A-5j5jA:undetectable | 4c49A-5j5jA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j72 | PUTATIVEN-ACETYLMURAMOYL-L-ALANINEAMIDASE,AUTOLYSINCWP6 (Clostridioidesdifficile) |
PF01520(Amidase_3)PF04122(CW_binding_2) | 5 | VAL A 424THR A 403ILE A 436ASN A 437SER A 434 | None | 1.13A | 4c49A-5j72A:undetectable | 4c49A-5j72A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lox | PEPTIDASE (Pseudomonasaeruginosa) |
no annotation | 5 | ALA A 15SER A 16ILE A 180SER A 178PHE A 215 | None | 1.25A | 4c49A-5loxA:undetectable | 4c49A-5loxA:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oce | PHOSPHATIDYLINOSITOLMANNOSIDEACYLTRANSFERASE (Mycolicibacteriumsmegmatis) |
no annotation | 5 | ALA A 199PHE A 213ILE A 276ASN A 275PHE A 212 | None | 1.29A | 4c49A-5oceA:undetectable | 4c49A-5oceA:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u39 | UDP-3-O-ACYL-N-ACETYLGLUCOSAMINEDEACETYLASE (Pseudomonasaeruginosa) |
PF03331(LpxC) | 5 | ALA A 172SER A 173VAL A 174ILE A 243HIS A 237 | NoneNoneNoneNone ZN A 501 ( 3.2A) | 1.07A | 4c49A-5u39A:undetectable | 4c49A-5u39A:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vwm | UDP-3-O-ACYL-N-ACETYLGLUCOSAMINEDEACETYLASE (Pseudomonasaeruginosa) |
PF03331(LpxC) | 5 | ALA A 172SER A 173VAL A 174ILE A 243HIS A 237 | NoneNoneNoneNone ZN A 402 ( 3.3A) | 1.08A | 4c49A-5vwmA:undetectable | 4c49A-5vwmA:24.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wde | KINESIN-LIKE PROTEINKIFC3 (Homo sapiens) |
PF00225(Kinesin) | 5 | SER A 746VAL A 452ILE A 479SER A 489PHE A 471 | NoneNoneNoneUNX A 920 ( 4.4A)None | 1.12A | 4c49A-5wdeA:undetectable | 4c49A-5wdeA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwz | UNPLACED GENOMICSCAFFOLDSUPERCONT1.36, WHOLEGENOME SHOTGUNSEQUENCE (Cladophialophorabantiana) |
no annotation | 5 | ALA A 108SER A 109VAL A 111THR A 260ILE A 209 | None | 1.27A | 4c49A-5xwzA:undetectable | 4c49A-5xwzA:12.67 |