SIMILAR PATTERNS OF AMINO ACIDS FOR 4BWL_C_MN9C1297_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1crz | TOLB PROTEIN (Escherichiacoli) |
PF04052(TolB_N)PF07676(PD40) | 5 | ILE A 16GLY A 13GLY A 45SER A 44PHE A 142 | None | 1.20A | 4bwlC-1crzA:undetectable | 4bwlC-1crzA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gjv | [3-METHYL-2-OXOBUTANOATE DEHYDROGENASE[LIPOAMIDE]] KINASE (Rattusnorvegicus) |
PF02518(HATPase_c)PF10436(BCDHK_Adom3) | 5 | ILE A 290LEU A 295THR A 364GLY A 363GLY A 361 | AGS A1383 ( 4.5A)NoneAGS A1383 (-4.1A)NoneNone | 1.25A | 4bwlC-1gjvA:undetectable | 4bwlC-1gjvA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h67 | CALPONIN ALPHA (Gallus gallus) |
PF00307(CH) | 5 | ILE A 38LEU A 124ASP A 56GLY A 57PHE A 106 | None | 1.21A | 4bwlC-1h67A:undetectable | 4bwlC-1h67A:17.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hl2 | N-ACETYLNEURAMINATELYASE SUBUNIT (Escherichiacoli) |
PF00701(DHDPS) | 9 | ILE A 139THR A 167GLY A 189TYR A 190ASP A 191GLU A 192GLY A 207SER A 208PHE A 252 | 3PY A 802 ( 4.9A)3PY A 802 (-3.6A)NoneNoneNoneNoneNoneNoneNone | 0.39A | 4bwlC-1hl2A:52.2 | 4bwlC-1hl2A:97.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kcx | DIHYDROPYRIMIDINASERELATED PROTEIN-1 (Mus musculus) |
PF01979(Amidohydro_1) | 5 | LEU A 196GLY A 332ASP A 71GLY A 330PHE A 392 | None | 1.24A | 4bwlC-1kcxA:8.0 | 4bwlC-1kcxA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kzh | PHOSPHOFRUCTOKINASE (Borreliellaburgdorferi) |
PF00365(PFK) | 5 | ILE A 173LEU A 79GLY A 447GLY A 93SER A 92 | None | 1.19A | 4bwlC-1kzhA:undetectable | 4bwlC-1kzhA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qo8 | FLAVOCYTOCHROME C3FUMARATE REDUCTASE (Shewanellafrigidimarina) |
PF00890(FAD_binding_2)PF14537(Cytochrom_c3_2) | 5 | ILE A 299LEU A 125ASP A 27GLY A 291SER A 271 | None | 1.19A | 4bwlC-1qo8A:undetectable | 4bwlC-1qo8A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uas | ALPHA-GALACTOSIDASE (Oryza sativa) |
PF16499(Melibiase_2)PF17450(Melibiase_2_C) | 5 | ILE A 260LEU A 261ASP A 188GLU A 219GLY A 223 | None | 1.21A | 4bwlC-1uasA:9.4 | 4bwlC-1uasA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1urh | 3-MERCAPTOPYRUVATESULFURTRANSFERASE (Escherichiacoli) |
PF00581(Rhodanese) | 5 | LEU A 132GLY A 121TYR A 92ASP A 93GLY A 95 | None | 1.20A | 4bwlC-1urhA:undetectable | 4bwlC-1urhA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w0m | TRIOSEPHOSPHATEISOMERASE (Thermoproteustenax) |
PF00121(TIM)PF05690(ThiG) | 5 | ILE A 160LEU A 194THR A 178GLY A 179GLY A 181 | NoneNoneNoneNonePO4 A1226 (-3.6A) | 0.97A | 4bwlC-1w0mA:13.0 | 4bwlC-1w0mA:25.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d2x | 2-DEOXY-SCYLLO-INOSOSE SYNTHASE (Bacilluscirculans) |
PF01761(DHQ_synthase) | 5 | ILE A 241LEU A 351GLY A 342GLY A 340SER A 339 | None | 1.12A | 4bwlC-2d2xA:2.8 | 4bwlC-2d2xA:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e3z | BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF00232(Glyco_hydro_1) | 5 | ILE A 34GLY A 178TYR A 179GLU A 193GLY A 182 | None | 1.20A | 4bwlC-2e3zA:10.1 | 4bwlC-2e3zA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2epg | HYPOTHETICAL PROTEINTTHA1785 (Thermusthermophilus) |
PF01139(RtcB) | 5 | LEU A 176GLY A 99ASP A 95GLY A 237SER A 238 | None | 1.09A | 4bwlC-2epgA:undetectable | 4bwlC-2epgA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exa | PENICILLIN-BINDINGPROTEIN 4 (Escherichiacoli) |
PF02113(Peptidase_S13) | 5 | ILE A 131LEU A 101GLY A 95GLY A 127SER A 126 | None | 1.12A | 4bwlC-2exaA:undetectable | 4bwlC-2exaA:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2go4 | UDP-3-O-[3-HYDROXYMYRISTOYL]N-ACETYLGLUCOSAMINEDEACETYLASE (Aquifexaeolicus) |
PF03331(LpxC) | 5 | ILE A 80GLY A 108ASP A 105GLU A 110GLY A 106 | None | 1.17A | 4bwlC-2go4A:undetectable | 4bwlC-2go4A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hmf | PROBABLEASPARTOKINASE (Methanocaldococcusjannaschii) |
PF00696(AA_kinase)PF01842(ACT)PF13840(ACT_7) | 5 | ILE A 350LEU A 351TYR A 262GLY A 264SER A 313 | None | 1.08A | 4bwlC-2hmfA:undetectable | 4bwlC-2hmfA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nwq | PROBABLE SHORT-CHAINDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00106(adh_short) | 5 | ILE A 126LEU A 122THR A 173GLY A 174GLY A 131 | None | 1.26A | 4bwlC-2nwqA:2.4 | 4bwlC-2nwqA:24.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o9r | BETA-GLUCOSIDASE B (Paenibacilluspolymyxa) |
PF00232(Glyco_hydro_1) | 5 | ILE A 36GLY A 175TYR A 176GLU A 190GLY A 179 | None | 1.20A | 4bwlC-2o9rA:10.5 | 4bwlC-2o9rA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pge | MENC (Desulfotaleapsychrophila) |
PF13378(MR_MLE_C) | 5 | ILE A 39LEU A 81GLY A 43ASP A 131GLY A 135 | None | 1.21A | 4bwlC-2pgeA:5.7 | 4bwlC-2pgeA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q0f | RNA URIDYLYLTRANSFERASE (Trypanosomabrucei) |
PF03828(PAP_assoc) | 5 | LEU A 321THR A 175GLY A 176GLY A 184SER A 185 | None | 1.22A | 4bwlC-2q0fA:undetectable | 4bwlC-2q0fA:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2reb | REC A (Escherichiacoli) |
PF00154(RecA) | 5 | ILE A 64ASP A 48GLY A 43SER A 44PHE A 260 | None | 1.13A | 4bwlC-2rebA:undetectable | 4bwlC-2rebA:24.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x24 | ACETYL-COACARBOXYLASE (Bos taurus) |
PF01039(Carboxyl_trans) | 5 | LEU A 270TYR A 135ASP A 132GLY A 235SER A 236 | None | 1.18A | 4bwlC-2x24A:undetectable | 4bwlC-2x24A:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ymb | MITDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF16565(MIT_C) | 5 | ILE A 94THR A 236GLY A 208GLY A 210PHE A 107 | None | 1.27A | 4bwlC-2ymbA:undetectable | 4bwlC-2ymbA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahy | BETA-GLUCOSIDASE (Trichodermareesei) |
PF00232(Glyco_hydro_1) | 5 | ILE A 30GLY A 173TYR A 174GLU A 188GLY A 177 | None | 1.17A | 4bwlC-3ahyA:10.3 | 4bwlC-3ahyA:23.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ber | PROBABLEATP-DEPENDENT RNAHELICASE DDX47 (Homo sapiens) |
PF00270(DEAD) | 5 | ILE A 108LEU A 104GLY A 76GLY A 73SER A 72 | NoneNoneNoneAMP A 300 (-3.3A)AMP A 300 (-4.1A) | 1.20A | 4bwlC-3berA:undetectable | 4bwlC-3berA:23.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bl6 | 5'-METHYLTHIOADENOSINENUCLEOSIDASE/S-ADENOSYLHOMOCYSTEINENUCLEOSIDASE (Staphylococcusaureus) |
PF01048(PNP_UDP_1) | 5 | GLY A 6GLU A 173GLY A 74SER A 75PHE A 206 | NoneFMC A 229 (-2.5A)NoneFMC A 229 (-3.0A)FMC A 229 (-4.6A) | 0.81A | 4bwlC-3bl6A:undetectable | 4bwlC-3bl6A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bq9 | PREDICTED ROSSMANNFOLDNUCLEOTIDE-BINDINGDOMAIN-CONTAININGPROTEIN (Idiomarinabaltica) |
PF03641(Lysine_decarbox)PF11892(DUF3412)PF14793(DUF4478) | 5 | ILE A 250LEU A 282GLY A 151GLU A 159GLY A 254 | NoneNoneNoneGOL A 463 ( 4.9A)SO4 A 460 (-3.5A) | 1.19A | 4bwlC-3bq9A:undetectable | 4bwlC-3bq9A:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bq9 | PREDICTED ROSSMANNFOLDNUCLEOTIDE-BINDINGDOMAIN-CONTAININGPROTEIN (Idiomarinabaltica) |
PF03641(Lysine_decarbox)PF11892(DUF3412)PF14793(DUF4478) | 5 | ILE A 250LEU A 282GLY A 152GLU A 159GLY A 254 | NoneNoneSO4 A 460 (-3.3A)GOL A 463 ( 4.9A)SO4 A 460 (-3.5A) | 1.20A | 4bwlC-3bq9A:undetectable | 4bwlC-3bq9A:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c0i | PERIPHERAL PLASMAMEMBRANE PROTEINCASK (Homo sapiens) |
PF00069(Pkinase) | 5 | ILE A 167GLY A 197TYR A 196GLY A 173SER A 172 | None | 1.00A | 4bwlC-3c0iA:undetectable | 4bwlC-3c0iA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | ILE A 64ASP A 48GLY A 43SER A 44PHE A 260 | None | 1.12A | 4bwlC-3cmtA:undetectable | 4bwlC-3cmtA:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | ILE A1064ASP A1048GLY A1043SER A1044PHE A1260 | None | 1.13A | 4bwlC-3cmtA:undetectable | 4bwlC-3cmtA:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | ILE A2064ASP A2048GLY A2043SER A2044PHE A2260 | None | 1.13A | 4bwlC-3cmtA:undetectable | 4bwlC-3cmtA:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | ILE A 64ASP A 48GLY A 43SER A 44PHE A 260 | None | 1.10A | 4bwlC-3cmuA:undetectable | 4bwlC-3cmuA:10.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | ILE A1064ASP A1048GLY A1043SER A1044PHE A1260 | None | 1.10A | 4bwlC-3cmuA:undetectable | 4bwlC-3cmuA:10.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | ILE A4064ASP A4048GLY A4043SER A4044PHE A4260 | None | 1.10A | 4bwlC-3cmuA:undetectable | 4bwlC-3cmuA:10.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | ILE A5064ASP A5048GLY A5043SER A5044PHE A5260 | None | 1.10A | 4bwlC-3cmuA:undetectable | 4bwlC-3cmuA:10.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmv | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | ILE A2064ASP A2048GLY A2043SER A2044PHE A2260 | None | 1.14A | 4bwlC-3cmvA:undetectable | 4bwlC-3cmvA:12.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cyv | UROPORPHYRINOGENDECARBOXYLASE (Shigellaflexneri) |
PF01208(URO-D) | 5 | ILE A 167LEU A 178THR A 153ASP A 208GLY A 211 | None | 1.23A | 4bwlC-3cyvA:6.4 | 4bwlC-3cyvA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm9 | SIGNAL RECOGNITIONPARTICLE RECEPTOR (Pyrococcusfuriosus) |
PF00448(SRP54)PF02881(SRP54_N) | 5 | ILE B 284GLY B 248ASP B 275GLY B 278PHE B 312 | None | 1.26A | 4bwlC-3dm9B:undetectable | 4bwlC-3dm9B:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dp9 | MTA/SAH NUCLEOSIDASE (Vibrio cholerae) |
PF01048(PNP_UDP_1) | 5 | GLY A 7GLU A 175GLY A 75SER A 76PHE A 208 | NoneBIG A 301 (-2.8A)NoneBIG A 301 (-3.3A)BIG A 301 (-4.3A) | 0.85A | 4bwlC-3dp9A:undetectable | 4bwlC-3dp9A:24.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eei | 5-METHYLTHIOADENOSINENUCLEOSIDASE/S-ADENOSYLHOMOCYSTEINENUCLEOSIDASE (Neisseriameningitidis) |
PF01048(PNP_UDP_1) | 5 | GLY A 10GLU A 178GLY A 78SER A 79PHE A 211 | NoneMTM A 234 (-2.6A)NoneMTM A 234 (-3.1A)MTM A 234 (-4.4A) | 0.86A | 4bwlC-3eeiA:undetectable | 4bwlC-3eeiA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fah | ALDEHYDEOXIDOREDUCTASE (Desulfovibriogigas) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 5 | ILE A 808LEU A 791GLY A 868GLY A 866SER A 865 | NoneNonePCD A 921 (-3.5A)PCD A 921 (-3.4A)PCD A 921 (-4.9A) | 1.24A | 4bwlC-3fahA:undetectable | 4bwlC-3fahA:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ff6 | ACETYL-COACARBOXYLASE 2 (Homo sapiens) |
PF01039(Carboxyl_trans) | 5 | LEU A1945TYR A1810ASP A1807GLY A1910SER A1911 | None | 1.25A | 4bwlC-3ff6A:undetectable | 4bwlC-3ff6A:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hul | HOMOSERINE KINASE (Listeriamonocytogenes) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | ILE A 159THR A 248GLY A 83GLY A 85SER A 86 | NoneNoneSO4 A 297 (-3.4A)SO4 A 297 (-3.3A)SO4 A 297 (-4.6A) | 1.09A | 4bwlC-3hulA:undetectable | 4bwlC-3hulA:24.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i8b | XYLULOSE KINASE (Bifidobacteriumadolescentis) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | ILE A 290LEU A 429GLY A 296GLY A 332SER A 333 | None | 0.90A | 4bwlC-3i8bA:undetectable | 4bwlC-3i8bA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jz4 | SUCCINATE-SEMIALDEHYDE DEHYDROGENASE[NADP+] (Escherichiacoli) |
PF00171(Aldedh) | 5 | ILE A 436LEU A 413GLY A 438GLY A 442SER A 279 | None | 1.14A | 4bwlC-3jz4A:undetectable | 4bwlC-3jz4A:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nvl | 2,3-BISPHOSPHOGLYCERATE-INDEPENDENTPHOSPHOGLYCERATEMUTASE (Trypanosomabrucei) |
PF01676(Metalloenzyme)PF06415(iPGM_N) | 5 | ILE A 195LEU A 179GLY A 198TYR A 162PHE A 278 | None | 1.17A | 4bwlC-3nvlA:undetectable | 4bwlC-3nvlA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o4v | MTA/SAH NUCLEOSIDASE (Escherichiacoli) |
PF01048(PNP_UDP_1) | 5 | GLY A 7GLU A 174GLY A 75SER A 76PHE A 207 | None4CT A 233 (-3.0A)None4CT A 233 (-3.2A)4CT A 233 (-4.5A) | 0.81A | 4bwlC-3o4vA:undetectable | 4bwlC-3o4vA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pqv | RCL1 PROTEIN (Kluyveromyceslactis) |
PF01137(RTC)PF05189(RTC_insert) | 5 | ILE A 80LEU A 105GLY A 61SER A 62PHE A 75 | None | 0.98A | 4bwlC-3pqvA:undetectable | 4bwlC-3pqvA:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qre | ENOYL-COA HYDRATASE,ECHA12_1 (Mycobacteriummarinum) |
PF00378(ECH_1) | 5 | ILE A 157LEU A 161THR A 126GLY A 124PHE A 180 | None | 1.23A | 4bwlC-3qreA:undetectable | 4bwlC-3qreA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s5r | TRANSCRIPTIONALREGULATOR TETRFAMILY (Syntrophusaciditrophicus) |
PF00440(TetR_N) | 5 | ILE A 94THR A 165GLY A 163GLY A 159PHE A 135 | None | 1.13A | 4bwlC-3s5rA:undetectable | 4bwlC-3s5rA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v44 | TOLL-LIKE RECEPTOR5B AND VARIABLELYMPHOCYTE RECEPTORB.61 CHIMERICPROTEIN (Eptatretusburgeri;Danio rerio) |
PF11921(DUF3439)PF13855(LRR_8) | 5 | ILE A 258LEU A 234THR A 256GLY A 255GLY A 288 | None | 1.15A | 4bwlC-3v44A:undetectable | 4bwlC-3v44A:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vc7 | PUTATIVEOXIDOREDUCTASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 5 | ILE A 11LEU A 123GLY A 14GLY A 38SER A 60 | None | 1.28A | 4bwlC-3vc7A:undetectable | 4bwlC-3vc7A:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zbq | PHIKZ039 (Pseudomonasvirus phiKZ) |
no annotation | 5 | ILE A 81LEU A 80THR A 111GLY A 109GLY A 13 | NoneNoneNoneGDP A 999 (-3.5A)GDP A 999 (-3.6A) | 1.27A | 4bwlC-3zbqA:undetectable | 4bwlC-3zbqA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b6j | PHOSPHOSERINEPHOSPHATASE (Thermococcusonnurineus) |
PF12710(HAD) | 5 | ILE A 7THR A 12GLY A 11GLY A 152PHE A 159 | None | 1.19A | 4bwlC-4b6jA:undetectable | 4bwlC-4b6jA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4brz | HALOALKANEDEHALOGENASE (Rhodobacteraceae) |
PF00561(Abhydrolase_1) | 5 | ILE A 30LEU A 50THR A 101GLY A 125SER A 291 | None | 1.01A | 4bwlC-4brzA:undetectable | 4bwlC-4brzA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cu8 | GLYCOSIDE HYDROLASE2 (Streptococcuspneumoniae) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF16355(DUF4982) | 5 | ILE A 565GLY A 512TYR A 511GLU A 524GLY A 520 | None | 1.26A | 4bwlC-4cu8A:10.9 | 4bwlC-4cu8A:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dao | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE (Bacillussubtilis) |
PF01048(PNP_UDP_1) | 5 | ILE A 69LEU A 184THR A 62GLY A 20GLY A 89 | None | 1.22A | 4bwlC-4daoA:undetectable | 4bwlC-4daoA:24.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ei8 | PLASMID REPLICATIONPROTEIN REPX (Bacillus cereus) |
PF00091(Tubulin) | 5 | ILE A 183LEU A 282THR A 149GLY A 120GLY A 27 | None | 1.27A | 4bwlC-4ei8A:2.8 | 4bwlC-4ei8A:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdw | LEUCINE RICHHYPOTHETICAL PROTEIN (Bacteroidesovatus) |
PF07523(Big_3)PF13306(LRR_5) | 5 | ILE A 219LEU A 198THR A 217ASP A 213PHE A 227 | None | 1.00A | 4bwlC-4fdwA:undetectable | 4bwlC-4fdwA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i0w | PROTEASE CSPB (Clostridiumperfringens) |
PF00082(Peptidase_S8) | 5 | ILE B 215THR B 216ASP B 179GLU B 177GLY B 184 | None | 1.26A | 4bwlC-4i0wB:undetectable | 4bwlC-4i0wB:21.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4imd | N-ACETYLNEURAMINATELYASE (Pasteurellamultocida) |
PF00701(DHDPS) | 8 | ILE A 138LEU A 141THR A 166GLY A 188ASP A 190GLU A 191GLY A 206SER A 207 | NoneNoneNoneKPI A 164 ( 4.4A)EDO A 303 (-3.4A)EDO A 303 (-3.4A)KPI A 164 ( 4.2A)EDO A 303 ( 4.0A) | 0.50A | 4bwlC-4imdA:42.2 | 4bwlC-4imdA:36.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k91 | D-ALA-D-ALA-CARBOXYPEPTIDASE (Pseudomonasaeruginosa) |
PF00768(Peptidase_S11)PF07943(PBP5_C) | 5 | ILE A 97THR A 47ASP A 140GLU A 117GLY A 143 | None | 0.99A | 4bwlC-4k91A:undetectable | 4bwlC-4k91A:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4le4 | BETA-GLUCANASE (Podosporaanserina) |
no annotation | 5 | ILE A 21GLY A 260ASP A 73GLY A 75SER A 76 | None | 0.81A | 4bwlC-4le4A:undetectable | 4bwlC-4le4A:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mca | GLYCEROLDEHYDROGENASE (Serratiaplymuthica) |
PF00465(Fe-ADH) | 5 | LEU A 127GLY A 249GLU A 178GLY A 244SER A 241 | NoneNoneNoneNone NA A1004 (-3.4A) | 1.27A | 4bwlC-4mcaA:3.2 | 4bwlC-4mcaA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mdp | BETA-GLUCOSIDASE (Humicola grisea) |
PF00232(Glyco_hydro_1) | 5 | ILE A 31GLY A 174TYR A 175GLU A 199SER A 191 | None | 1.17A | 4bwlC-4mdpA:10.5 | 4bwlC-4mdpA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mwt | LYSOSOMAL PROTECTIVEPROTEIN (Homo sapiens) |
PF00450(Peptidase_S10) | 5 | LEU A 174GLY A 177ASP A 380GLY A 179SER A 181 | LEU A 174 ( 0.5A)GLY A 177 ( 0.0A)ASP A 380 ( 0.5A)GLY A 179 ( 0.0A)SER A 181 ( 0.0A) | 1.13A | 4bwlC-4mwtA:undetectable | 4bwlC-4mwtA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n81 | INOSITOLMONOPHOSPHATASE (Zymomonasmobilis) |
PF00459(Inositol_P) | 5 | ILE A 142LEU A 195THR A 135GLY A 220GLY A 223 | None | 1.28A | 4bwlC-4n81A:undetectable | 4bwlC-4n81A:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4npa | PUTATIVEUNCHARACTERIZEDPROTEIN (Vibrio cholerae) |
PF03641(Lysine_decarbox)PF11892(DUF3412)PF14793(DUF4478) | 5 | ILE A 256LEU A 288GLY A 157GLU A 165GLY A 260 | NoneNoneNoneNoneSO4 A 501 (-3.4A) | 1.22A | 4bwlC-4npaA:undetectable | 4bwlC-4npaA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4npa | PUTATIVEUNCHARACTERIZEDPROTEIN (Vibrio cholerae) |
PF03641(Lysine_decarbox)PF11892(DUF3412)PF14793(DUF4478) | 5 | ILE A 256LEU A 288GLY A 158GLU A 165GLY A 260 | NoneNoneSO4 A 501 (-3.6A)NoneSO4 A 501 (-3.4A) | 1.21A | 4bwlC-4npaA:undetectable | 4bwlC-4npaA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oue | PUTATIVE LIPOPROTEIN (Bacteroidesthetaiotaomicron) |
PF00754(F5_F8_type_C)PF01120(Alpha_L_fucos) | 5 | LEU A 175GLY A 147TYR A 168ASP A 150GLY A 102 | None | 1.25A | 4bwlC-4oueA:7.4 | 4bwlC-4oueA:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qez | 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE (Bacillusanthracis) |
no annotation | 5 | GLY B 7GLU B 175GLY B 75SER B 76PHE B 208 | NoneTRS B 302 (-2.7A)TRS B 302 ( 4.6A)TRS B 302 (-2.8A)TRS B 302 ( 4.7A) | 0.84A | 4bwlC-4qezB:undetectable | 4bwlC-4qezB:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4re2 | BETA-MANNOSIDASE/BETA-GLUCOSIDASE (Oryza sativa) |
PF00232(Glyco_hydro_1) | 5 | ILE A 46GLY A 187TYR A 188GLU A 210GLY A 191 | None | 1.25A | 4bwlC-4re2A:10.9 | 4bwlC-4re2A:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tym | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE (Streptococcusagalactiae) |
PF01048(PNP_UDP_1) | 5 | ILE A 91LEU A 207THR A 84GLY A 42GLY A 111 | NoneNoneNoneSO4 A 301 (-3.3A)SO4 A 301 (-3.6A) | 1.09A | 4bwlC-4tymA:undetectable | 4bwlC-4tymA:24.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u48 | PUTATIVE INNERMEMBRANE LIPOPROTEIN (Salmonellaenterica) |
PF00207(A2M)PF01835(A2M_N)PF07703(A2M_N_2)PF10569(Thiol-ester_cl)PF11974(MG1) | 5 | ILE A 251LEU A 254THR A 229GLY A 230PHE A 279 | None | 1.25A | 4bwlC-4u48A:undetectable | 4bwlC-4u48A:11.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uhq | LARGE COMPONENT OFPYOCIN AP41 (Pseudomonasaeruginosa) |
no annotation | 5 | ILE A 674GLY A 651ASP A 753GLY A 649PHE A 689 | None | 1.09A | 4bwlC-4uhqA:undetectable | 4bwlC-4uhqA:19.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4woq | N-ACETYLNEURAMINATELYASE (Clostridioidesdifficile) |
PF00701(DHDPS) | 8 | ILE A 149LEU A 152THR A 177GLY A 199ASP A 201GLU A 202GLY A 217SER A 218 | None | 0.39A | 4bwlC-4woqA:42.9 | 4bwlC-4woqA:35.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yhs | MONOSACCHARIDE ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN, CUT2 FAMILY (Bradyrhizobiumsp. BTAi1) |
PF13407(Peripla_BP_4) | 5 | ILE A 124LEU A 101GLY A 122ASP A 145GLY A 149 | None | 1.04A | 4bwlC-4yhsA:undetectable | 4bwlC-4yhsA:25.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yit | MEGANUCLEASE I-AABMI (Gremmeniellaabietina) |
PF00961(LAGLIDADG_1) | 5 | ILE A 156GLY A 8GLY A 164SER A 163PHE A 239 | None | 1.28A | 4bwlC-4yitA:undetectable | 4bwlC-4yitA:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z8z | UNCHARACTERIZEDPROTEIN (Ruminiclostridiumthermocellum) |
no annotation | 5 | ILE A 264LEU A 292THR A 206GLY A 190PHE A 283 | None | 1.24A | 4bwlC-4z8zA:undetectable | 4bwlC-4z8zA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5afd | N-ACETYLNEURAMINATELYASE (Aliivibriosalmonicida) |
PF00701(DHDPS) | 5 | GLY A 191ASP A 193GLU A 194GLY A 209SER A 210 | NoneEDO A1304 (-3.7A)EDO A1304 (-3.0A)NoneEDO A1304 ( 3.9A) | 0.32A | 4bwlC-5afdA:38.2 | 4bwlC-5afdA:27.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dk6 | 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE (Colwelliapsychrerythraea) |
PF01048(PNP_UDP_1) | 5 | GLY A 7GLU A 180GLY A 75SER A 76PHE A 213 | NoneNoneNoneADE A 302 ( 3.7A)GLY A 301 ( 4.7A) | 0.84A | 4bwlC-5dk6A:undetectable | 4bwlC-5dk6A:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dx5 | METHIONINEGAMMA-LYASE (Clostridiumsporogenes) |
PF01053(Cys_Met_Meta_PP) | 5 | ILE A 398LEU A 395GLY A 321GLU A 288GLY A 373 | None | 1.28A | 4bwlC-5dx5A:undetectable | 4bwlC-5dx5A:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epg | ALDEHYDE OXIDASE (Homo sapiens) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 5 | ILE A 291LEU A 249GLY A 309GLY A 307SER A 413 | None | 1.20A | 4bwlC-5epgA:undetectable | 4bwlC-5epgA:13.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f1y | MCCC FAMILY PROTEIN (Bacillus cereus) |
PF02016(Peptidase_S66) | 5 | ILE A 88ASP A 26GLU A 28GLY A 57SER A 58 | None | 1.17A | 4bwlC-5f1yA:undetectable | 4bwlC-5f1yA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fi5 | TETRAHYDROALSTONINESYNTHASE (Catharanthusroseus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ILE A 349LEU A 353GLY A 52ASP A 57GLY A 75 | None | 1.18A | 4bwlC-5fi5A:undetectable | 4bwlC-5fi5A:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g06 | EXOSOME COMPLEXCOMPONENT SKI6EXOSOME COMPLEXCOMPONENT RRP4 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF01138(RNase_PH)PF03725(RNase_PH_C)PF14382(ECR1_N)PF15985(KH_6) | 5 | GLY H 58TYR H 81ASP B 156GLY B 191SER B 193 | None | 1.27A | 4bwlC-5g06H:undetectable | 4bwlC-5g06H:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gnx | BETA-GLUCOSIDASE (metagenome) |
PF00232(Glyco_hydro_1) | 5 | ILE A 39GLY A 179TYR A 180GLU A 194GLY A 183 | None | 1.24A | 4bwlC-5gnxA:10.9 | 4bwlC-5gnxA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h82 | HETEROYOHIMBINESYNTHASE THAS2 (Catharanthusroseus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ILE A 364LEU A 368GLY A 46ASP A 51GLY A 69 | None | 1.07A | 4bwlC-5h82A:undetectable | 4bwlC-5h82A:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihw | SERINE-ASPARTATEREPEAT-CONTAININGPROTEIN E (Staphylococcusaureus) |
PF10425(SdrG_C_C) | 5 | ILE A 564THR A 486GLY A 470GLY A 567SER A 585 | None | 1.14A | 4bwlC-5ihwA:undetectable | 4bwlC-5ihwA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihy | UNCHARACTERIZEDPROTEIN (Bacillussubtilis) |
PF01966(HD) | 5 | ILE A 200LEU A 193GLY A 150GLY A 147PHE A 138 | None | 1.08A | 4bwlC-5ihyA:undetectable | 4bwlC-5ihyA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jrj | PROTEIN RECA (Herbaspirillumseropedicae) |
PF00154(RecA) | 5 | ILE A 71ASP A 55GLY A 50SER A 51PHE A 267 | None | 1.07A | 4bwlC-5jrjA:undetectable | 4bwlC-5jrjA:22.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5kzd | N-ACETYLNEURAMINATELYASE (Staphylococcusaureus) |
PF00701(DHDPS) | 5 | GLY A 189ASP A 191GLU A 192GLY A 207SER A 208 | RCJ A 301 (-3.6A)RCJ A 301 (-2.5A)RCJ A 301 (-3.1A)RCJ A 301 (-3.2A)RCJ A 301 (-3.2A) | 0.37A | 4bwlC-5kzdA:39.4 | 4bwlC-5kzdA:36.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m0k | BETA-XYLANASE (Cellulomonasflavigena) |
no annotation | 5 | ILE A 262GLY A 17TYR A 15ASP A 39GLY A 6 | None | 1.24A | 4bwlC-5m0kA:9.9 | 4bwlC-5m0kA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ue1 | 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE (Aliivibriofischeri) |
PF01048(PNP_UDP_1) | 5 | GLY A 7GLU A 175GLY A 75SER A 76PHE A 208 | NoneTRS A 302 (-2.7A)TRS A 302 ( 4.9A)TRS A 302 (-2.8A)TRS A 302 (-3.9A) | 0.84A | 4bwlC-5ue1A:undetectable | 4bwlC-5ue1A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vug | UNCHARACTERIZEDPROTEIN RV2277C (Mycobacteriumtuberculosis) |
PF03009(GDPD) | 5 | ILE A 110LEU A 106THR A 142GLY A 143GLY A 146 | None | 1.12A | 4bwlC-5vugA:3.2 | 4bwlC-5vugA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xhu | FERREDOXIN--NADPREDUCTASE (Bacillussubtilis) |
no annotation | 5 | ILE A 70LEU A 69GLY A 15GLY A 19PHE A 302 | None | 1.07A | 4bwlC-5xhuA:undetectable | 4bwlC-5xhuA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xn8 | GLYCEROLDEHYDROGENASE (unidentified) |
PF00465(Fe-ADH) | 5 | LEU A 127GLY A 249GLU A 178GLY A 244SER A 241 | None | 1.21A | 4bwlC-5xn8A:3.0 | 4bwlC-5xn8A:24.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bxa | TOLL-LIKE RECEPTOR5B, VARIABLELYMPHOCYTE RECEPTORB CHIMERA (Eptatretusburgeri;Danio rerio) |
no annotation | 5 | ILE A 258LEU A 234THR A 256GLY A 255GLY A 288 | None | 1.17A | 4bwlC-6bxaA:undetectable | 4bwlC-6bxaA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bxa | TOLL-LIKE RECEPTOR5B, VARIABLELYMPHOCYTE RECEPTORB CHIMERAVARIABLE LYMPHOCYTERECEPTOR 2 (Eptatretusburgeri;Danio rerio;Petromyzonmarinus) |
no annotationno annotation | 5 | ILE A 35LEU A 56ASP C 34GLY C 55SER C 36 | None | 1.23A | 4bwlC-6bxaA:undetectable | 4bwlC-6bxaA:undetectable |