SIMILAR PATTERNS OF AMINO ACIDS FOR 4BLV_A_SAMA1281_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a8s | CHLOROPEROXIDASE F (Pseudomonasfluorescens) |
PF00561(Abhydrolase_1) | 4 | HIS A 253SER A 94GLU A 99ASP A 70 | PPI A 278 ( 4.0A)PPI A 278 ( 2.7A)NoneNone | 1.39A | 4blvA-1a8sA:2.1 | 4blvA-1a8sA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a9x | CARBAMOYL PHOSPHATESYNTHETASE (SMALLCHAIN) (Escherichiacoli) |
PF00117(GATase)PF00988(CPSase_sm_chain) | 4 | HIS B1795SER B1831GLU B1818ASP B1834 | None | 1.36A | 4blvA-1a9xB:2.2 | 4blvA-1a9xB:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c4k | PROTEIN (ORNITHINEDECARBOXYLASE) (Lactobacillussp. 30A) |
PF01276(OKR_DC_1)PF03709(OKR_DC_1_N)PF03711(OKR_DC_1_C) | 4 | HIS A 354SER A 352GLU A 314ASP A 219 | PLP A 955 (-4.1A)PLP A 955 (-2.8A)NoneNone | 1.28A | 4blvA-1c4kA:3.8 | 4blvA-1c4kA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1czi | CHYMOSIN (Bos taurus) |
PF00026(Asp) | 4 | SER E 3GLU E 162ASP E 156ASP E 171 | None | 1.40A | 4blvA-1cziE:undetectable | 4blvA-1cziE:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dxe | 2-DEHYDRO-3-DEOXY-GALACTARATE ALDOLASE (Escherichiacoli) |
PF03328(HpcH_HpaI) | 4 | HIS A 50GLU A 101ASP A 159ASP A 179 | NoneNoneNone MG A 901 (-3.2A) | 1.28A | 4blvA-1dxeA:undetectable | 4blvA-1dxeA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gpj | GLUTAMYL-TRNAREDUCTASE (Methanopyruskandleri) |
PF00745(GlutR_dimer)PF01488(Shikimate_DH)PF05201(GlutR_N) | 4 | SER A 393GLU A 401ASP A 343ASP A 333 | None | 1.14A | 4blvA-1gpjA:4.7 | 4blvA-1gpjA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i7n | SYNAPSIN II (Rattusnorvegicus) |
PF02078(Synapsin)PF02750(Synapsin_C) | 4 | HIS A 275SER A 392GLU A 387ASP A 314 | None | 1.38A | 4blvA-1i7nA:undetectable | 4blvA-1i7nA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l9y | FEZ-1 B-LACTAMASE (Fluoribactergormanii) |
PF00753(Lactamase_B) | 4 | HIS A 196HIS A 263SER A 262ASP A 176 | ZN A 1 ( 3.3A) ZN A 2 ( 3.3A)NoneNone | 1.35A | 4blvA-1l9yA:undetectable | 4blvA-1l9yA:23.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lfw | PEPV (Lactobacillusdelbrueckii) |
PF01546(Peptidase_M20) | 4 | HIS A 269GLU A 179ASP A 449ASP A 119 | AEP A 683 (-4.0A)NoneNone ZN A1001 (-2.4A) | 1.39A | 4blvA-1lfwA:undetectable | 4blvA-1lfwA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mjf | SPERMIDINE SYNTHASE (Pyrococcusfuriosus) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 4 | HIS A 61GLU A 104ASP A 141ASP A 158 | None | 1.36A | 4blvA-1mjfA:11.6 | 4blvA-1mjfA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qq0 | CARBONIC ANHYDRASE (Methanosarcinathermophila) |
PF00132(Hexapep)PF14602(Hexapep_2) | 4 | HIS A 193SER A 192GLU A 184ASP A 187 | None | 1.13A | 4blvA-1qq0A:undetectable | 4blvA-1qq0A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w36 | EXODEOXYRIBONUCLEASEV GAMMA CHAIN (Escherichiacoli) |
PF04257(Exonuc_V_gamma) | 4 | HIS C 237HIS C 267GLU C 33ASP C 28 | None | 1.15A | 4blvA-1w36C:undetectable | 4blvA-1w36C:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z48 | PROBABLENADH-DEPENDENTFLAVINOXIDOREDUCTASE YQJM (Bacillussubtilis) |
PF00724(Oxidored_FMN) | 4 | HIS A 164SER A 217GLU A 173ASP A 125 | FMN A1500 (-3.9A)NoneNoneNone | 1.28A | 4blvA-1z48A:undetectable | 4blvA-1z48A:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zoi | ESTERASE (Pseudomonasputida) |
PF00561(Abhydrolase_1) | 4 | HIS A 256SER A 97GLU A 102ASP A 73 | None | 1.40A | 4blvA-1zoiA:2.2 | 4blvA-1zoiA:24.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2buc | DIPEPTIDYL PEPTIDASEIV (Sus scrofa) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 4 | HIS A 740SER A 630GLU A 545ASP A 556 | SO4 A1769 ( 4.1A)SO4 A1769 ( 3.0A)NoneNone | 1.35A | 4blvA-2bucA:2.1 | 4blvA-2bucA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ec3 | FIBRONECTIN (Homo sapiens) |
PF00039(fn1) | 4 | HIS A 60SER A 44GLU A 31ASP A 34 | None | 1.38A | 4blvA-2ec3A:undetectable | 4blvA-2ec3A:10.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ei0 | 1,2-DIHYDROXYNAPHTHALENE DIOXYGENASE (Pseudomonas sp.C18) |
PF00903(Glyoxalase) | 4 | HIS A 247HIS A 215GLU A 177ASP A 276 | BP7 A 400 (-3.2A)FE2 A 399 ( 3.3A) MG A 398 (-2.5A)BP7 A 402 (-2.7A) | 1.03A | 4blvA-2ei0A:undetectable | 4blvA-2ei0A:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f7v | AECTYLCITRULLINEDEACETYLASE (Xanthomonascampestris) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | HIS A 51SER A 57ASP A 103ASP A 129 | NoneNone CO A5367 (-2.2A)None | 1.26A | 4blvA-2f7vA:undetectable | 4blvA-2f7vA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsn | PHOSPHODIESTERASE-NUCLEOTIDEPYROPHOSPHATASE (Xanthomonascitri) |
PF01663(Phosphodiest) | 4 | HIS A 258HIS A 94SER A 52ASP A 62 | ZN A1000 (-3.2A)NoneNoneNone | 1.33A | 4blvA-2gsnA:2.7 | 4blvA-2gsnA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iv2 | FORMATEDEHYDROGENASE H (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 4 | HIS X 149GLU X 385ASP X 101ASP X 349 | None | 1.32A | 4blvA-2iv2X:2.1 | 4blvA-2iv2X:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ixo | SERINE/THREONINE-PROTEIN PHOSPHATASE 2AACTIVATOR 1 (Saccharomycescerevisiae) |
PF03095(PTPA) | 4 | HIS A 304SER A 138ASP A 205ASP A 143 | None | 1.40A | 4blvA-2ixoA:undetectable | 4blvA-2ixoA:23.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oo3 | PROTEIN INVOLVED INCATABOLISM OFEXTERNAL DNA (Legionellapneumophila) |
PF04378(RsmJ) | 5 | HIS A 19SER A 101GLU A 119ASP A 144ASP A 165 | None | 0.70A | 4blvA-2oo3A:38.9 | 4blvA-2oo3A:38.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p0k | POLYCOMB PROTEINSCMH1 (Homo sapiens) |
PF02820(MBT) | 4 | HIS A 45HIS A 164SER A 163ASP A 106 | None | 1.35A | 4blvA-2p0kA:undetectable | 4blvA-2p0kA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pt6 | SPERMIDINE SYNTHASE (Plasmodiumfalciparum) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 4 | HIS A 103GLU A 147ASP A 178ASP A 196 | S4M A 501 (-3.7A)S4M A 501 (-2.7A)S4M A 501 (-3.3A)S4M A 501 (-2.6A) | 1.37A | 4blvA-2pt6A:11.2 | 4blvA-2pt6A:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r2c | 28 KDA OUTERMEMBRANE PROTEINOMP28 (Porphyromonasgingivalis) |
PF11551(Omp28) | 4 | HIS A 173SER A 155GLU A 152ASP A 95 | None | 1.19A | 4blvA-2r2cA:undetectable | 4blvA-2r2cA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r2d | ZN-DEPENDENTHYDROLASES (Agrobacteriumfabrum) |
PF00753(Lactamase_B) | 4 | HIS A 113SER A 110ASP A 238ASP A 213 | ZN A 278 ( 3.2A)NoneNone ZN A 277 (-2.0A) | 1.32A | 4blvA-2r2dA:undetectable | 4blvA-2r2dA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uuu | ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE (Dictyosteliumdiscoideum) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 4 | HIS A 12SER A -1GLU A 152ASP A 108 | None | 1.41A | 4blvA-2uuuA:undetectable | 4blvA-2uuuA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vg8 | HYDROQUINONEGLUCOSYLTRANSFERASE (Arabidopsisthaliana) |
PF00201(UDPGT) | 4 | HIS A 19SER A 14GLU A 45ASP A 75 | EDO A1480 ( 3.8A)NoneNoneNone | 1.13A | 4blvA-2vg8A:2.5 | 4blvA-2vg8A:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w5s | PROCESSED GLYCEROLPHOSPHATELIPOTEICHOIC ACIDSYNTHASE (Staphylococcusaureus) |
PF00884(Sulfatase) | 4 | HIS A 253HIS A 476SER A 256ASP A 425 | None MN A1642 ( 3.4A) MN A1642 ( 4.6A)None | 1.15A | 4blvA-2w5sA:3.2 | 4blvA-2w5sA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wjf | TYROSINE-PROTEINPHOSPHATASE CPSB (Streptococcuspneumoniae) |
no annotation | 4 | HIS A 5HIS A 201GLU A 138ASP A 141 | MN A1246 (-3.4A) MN A1247 ( 3.3A)NoneNone | 1.37A | 4blvA-2wjfA:undetectable | 4blvA-2wjfA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wqp | POLYSIALIC ACIDCAPSULE BIOSYNTHESISPROTEIN SIAC (Neisseriameningitidis) |
PF03102(NeuB)PF08666(SAF) | 4 | HIS A 215SER A 251ASP A 76ASP A 247 | MN A1351 ( 3.3A)NoneEDO A1356 (-4.4A)WQP A1350 (-2.8A) | 1.39A | 4blvA-2wqpA:undetectable | 4blvA-2wqpA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x1m | METHIONYL-TRNASYNTHETASE (Mycolicibacteriumsmegmatis) |
PF09334(tRNA-synt_1g) | 4 | HIS A 52HIS A 100ASP A 130ASP A 50 | NoneNoneNoneMET A 600 (-4.3A) | 1.29A | 4blvA-2x1mA:undetectable | 4blvA-2x1mA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x7v | PROBABLEENDONUCLEASE 4 (Thermotogamaritima) |
PF01261(AP_endonuc_2) | 4 | HIS A 230HIS A 109ASP A 188ASP A 178 | ZN A1289 (-3.2A) ZN A1287 (-3.3A)None ZN A1288 (-3.1A) | 1.30A | 4blvA-2x7vA:undetectable | 4blvA-2x7vA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yb4 | AMIDOHYDROLASE (Chromobacteriumviolaceum) |
PF02811(PHP) | 4 | HIS A 9HIS A 75GLU A 254ASP A 248 | None | 1.34A | 4blvA-2yb4A:undetectable | 4blvA-2yb4A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yeq | ALKALINE PHOSPHATASED (Bacillussubtilis) |
PF09423(PhoD)PF16655(PhoD_N) | 4 | HIS A 382HIS A 211GLU A 503ASP A 380 | FE A1524 (-3.4A)PO4 A1527 (-4.0A)None CA A1525 ( 3.4A) | 1.26A | 4blvA-2yeqA:undetectable | 4blvA-2yeqA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yeq | ALKALINE PHOSPHATASED (Bacillussubtilis) |
PF09423(PhoD)PF16655(PhoD_N) | 4 | HIS A 510HIS A 382SER A 412ASP A 151 | PO4 A1527 (-4.1A) FE A1524 (-3.4A) FE A1524 ( 4.0A) CA A1525 (-2.4A) | 1.10A | 4blvA-2yeqA:undetectable | 4blvA-2yeqA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zsu | SPERMIDINE SYNTHASE (Pyrococcushorikoshii) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 4 | HIS A 63GLU A 107ASP A 144ASP A 161 | AG3 A1001 (-4.0A)NoneNoneAG3 A1001 (-2.8A) | 1.19A | 4blvA-2zsuA:12.1 | 4blvA-2zsuA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dul | O-METHYLTRANSFERASE,PUTATIVE (Bacillus cereus) |
PF01596(Methyltransf_3) | 4 | HIS A 40SER A 72GLU A 90ASP A 140 | None | 1.19A | 4blvA-3dulA:11.9 | 4blvA-3dulA:25.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ez0 | UNCHARACTERIZEDPROTEIN WITHFERRITIN-LIKE FOLD (Arthrobactersp. FB24) |
PF13794(MiaE_2) | 4 | HIS A 59SER A 111ASP A 36ASP A 108 | UNL A 500 (-3.7A)UNL A 500 (-3.5A)NoneNone | 1.40A | 4blvA-3ez0A:undetectable | 4blvA-3ez0A:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fby | CARTILAGE OLIGOMERICMATRIX PROTEIN (Homo sapiens) |
PF02412(TSP_3)PF05735(TSP_C) | 4 | SER A 681GLU A 559ASP A 310ASP A 271 | NoneNoneNone CA A 801 ( 2.8A) | 1.38A | 4blvA-3fbyA:undetectable | 4blvA-3fbyA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fm0 | PROTEIN CIAO1 (Homo sapiens) |
PF00400(WD40) | 4 | HIS A 155SER A 199ASP A 273ASP A 257 | None | 1.38A | 4blvA-3fm0A:undetectable | 4blvA-3fm0A:24.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3glq | ADENOSYLHOMOCYSTEINASE (Burkholderiapseudomallei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | HIS A 344SER A 60ASP A 115ASP A 142 | RAB A 602 ( 3.5A)NoneNoneNone | 1.33A | 4blvA-3glqA:4.8 | 4blvA-3glqA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gr8 | NADPH DEHYDROGENASE (Geobacilluskaustophilus) |
PF00724(Oxidored_FMN) | 4 | HIS A 164SER A 217GLU A 173ASP A 125 | FMN A 341 (-4.0A)NoneNoneNone | 1.28A | 4blvA-3gr8A:undetectable | 4blvA-3gr8A:24.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gxa | OUTER MEMBRANELIPOPROTEIN GNA1946 (Neisseriameningitidis) |
PF03180(Lipoprotein_9) | 4 | HIS A 100SER A 152GLU A 110ASP A 150 | MET A 296 (-3.6A)NoneNoneNone | 1.34A | 4blvA-3gxaA:undetectable | 4blvA-3gxaA:24.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hpf | MUCONATECYCLOISOMERASE (Oceanobacillusiheyensis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | HIS A 246GLU A 218ASP A 159ASP A 322 | MG A 401 ( 3.3A)NoneNoneNone | 1.32A | 4blvA-3hpfA:undetectable | 4blvA-3hpfA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ibr | BACTERIOPHYTOCHROME (Pseudomonasaeruginosa) |
PF00360(PHY)PF01590(GAF)PF08446(PAS_2) | 4 | HIS A 247HIS A 277SER A 275ASP A 169 | BLA A 900 (-3.8A)BLA A 900 (-4.2A)BLA A 900 (-2.9A)None | 1.40A | 4blvA-3ibrA:undetectable | 4blvA-3ibrA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihm | STYRENEMONOOXYGENASE A (Pseudomonasputida) |
no annotation | 4 | HIS A 50HIS A 16SER A 312ASP A 384 | None | 1.19A | 4blvA-3ihmA:2.2 | 4blvA-3ihmA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-SPLICINGFACTOR SPP42 (Schizosaccharomycespombe) |
PF08082(PRO8NT)PF08083(PROCN)PF10596(U6-snRNA_bdg)PF10597(U5_2-snRNA_bdg)PF10598(RRM_4)PF12134(PRP8_domainIV) | 4 | SER A1362GLU A1510ASP A1730ASP A1696 | None | 1.13A | 4blvA-3jb9A:undetectable | 4blvA-3jb9A:8.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kgy | BIFUNCTIONALDEAMINASE-REDUCTASEDOMAIN PROTEIN (Chloroflexusaurantiacus) |
PF01872(RibD_C) | 4 | HIS A 206SER A 9GLU A 168ASP A 145 | NoneNDP A 301 (-4.5A)NoneNone | 1.41A | 4blvA-3kgyA:undetectable | 4blvA-3kgyA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kzp | PUTATIVE DIGUANYLATECYCLASE/PHOSPHODIESTERASE (Listeriamonocytogenes) |
PF00563(EAL) | 4 | HIS A 143GLU A 23ASP A 15ASP A 201 | None | 1.34A | 4blvA-3kzpA:undetectable | 4blvA-3kzpA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lij | CALCIUM/CALMODULINDEPENDENT PROTEINKINASE WITH A KINASEDOMAIN AND 4CALMODULIN LIKE EFHANDS (Cryptosporidiumparvum) |
PF00069(Pkinase)PF13499(EF-hand_7) | 4 | HIS A 118SER A 170GLU A 314ASP A 379 | NoneNoneNone CA A 1 (-3.3A) | 1.17A | 4blvA-3lijA:undetectable | 4blvA-3lijA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mpd | NUCLEOSIDEDIPHOSPHATE KINASE (Encephalitozooncuniculi) |
PF00334(NDK) | 4 | HIS A 51HIS A 115GLU A 121ASP A 118 | None | 1.15A | 4blvA-3mpdA:undetectable | 4blvA-3mpdA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opy | 6-PHOSPHOFRUCTO-1-KINASE ALPHA-SUBUNIT6-PHOSPHOFRUCTO-1-KINASE BETA-SUBUNIT (Komagataellapastoris;Komagataellapastoris) |
PF00365(PFK)PF00365(PFK) | 4 | HIS A 493SER B 365ASP A 314ASP A 221 | SO4 B 943 (-4.2A)NoneSO4 A 991 (-4.7A)None | 1.32A | 4blvA-3opyA:undetectable | 4blvA-3opyA:14.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s2j | DIPEPTIDASE (Streptomycescoelicolor) |
PF01244(Peptidase_M19) | 4 | HIS A 212SER A 66ASP A 333ASP A 22 | ZN A 403 ( 3.3A) ZN A 402 ( 3.9A)None ZN A 402 ( 2.2A) | 1.32A | 4blvA-3s2jA:undetectable | 4blvA-3s2jA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t8l | ADENINE DEAMINASE 2 (Agrobacteriumfabrum) |
PF01979(Amidohydro_1)PF13382(Adenine_deam_C) | 4 | HIS A 239HIS A 122ASP A 304ASP A 290 | UNX A 606 ( 3.6A)UNX A 607 ( 3.5A)NoneNone | 1.13A | 4blvA-3t8lA:undetectable | 4blvA-3t8lA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u60 | DNA POLYMERASEACCESSORY PROTEIN 62 (Escherichiavirus T4) |
PF16790(Phage_clamp_A) | 4 | SER A 19GLU A 12ASP A 30ASP A 21 | None | 1.40A | 4blvA-3u60A:undetectable | 4blvA-3u60A:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ux8 | EXCINUCLEASE ABC, ASUBUNIT (Geobacillus sp.Y412MC52) |
PF00005(ABC_tran) | 4 | HIS A 886SER A 639GLU A 903ASP A 521 | None | 1.34A | 4blvA-3ux8A:2.8 | 4blvA-3ux8A:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v0a | NTNH (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07953(Toxin_R_bind_N)PF08470(NTNH_C) | 4 | SER B 890GLU B 837ASP B 733ASP B 892 | None | 1.27A | 4blvA-3v0aB:undetectable | 4blvA-3v0aB:12.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bed | HEMOCYANIN KLH1 (Megathuracrenulata) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | HIS A 491HIS A 606GLU A 595ASP A 774 | CUO A9002 (-3.4A)CUO A9002 (-3.3A)NoneNone | 1.31A | 4blvA-4bedA:undetectable | 4blvA-4bedA:11.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bed | HEMOCYANIN KLH1 (Megathuracrenulata) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | HIS A 905HIS A1019GLU A1008ASP A1188 | CUO A9003 (-3.5A)CUO A9003 (-3.4A)NoneNone | 1.36A | 4blvA-4bedA:undetectable | 4blvA-4bedA:11.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bed | HEMOCYANIN KLH1 (Megathuracrenulata) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | HIS B1734HIS B1851GLU B1840ASP B2019 | CUO B9005 (-3.4A)CUO B9005 (-3.2A)NoneNone | 1.30A | 4blvA-4bedB:undetectable | 4blvA-4bedB:10.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4blu | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE J (Escherichiacoli) |
PF04378(RsmJ) | 5 | HIS A 19SER A 100GLU A 118ASP A 143ASP A 164 | NoneNoneNoneNoneTRS A1281 ( 3.0A) | 0.41A | 4blvA-4bluA:46.6 | 4blvA-4bluA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cw4 | BETA-KETOACYLSYNTHASE (Pseudomonasaeruginosa) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | HIS A 244SER A 239GLU A 315ASP A 230 | None | 0.87A | 4blvA-4cw4A:undetectable | 4blvA-4cw4A:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ddw | REVERSE GYRASE (Thermotogamaritima) |
PF00270(DEAD)PF01131(Topoisom_bac)PF01751(Toprim) | 4 | HIS A 9SER A 617ASP A 623ASP A 645 | None | 1.26A | 4blvA-4ddwA:2.5 | 4blvA-4ddwA:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dvg | RHO-LIKE SMALLGTPASE (Entamoebahistolytica) |
PF00071(Ras) | 4 | SER A 111GLU A 148ASP A 143ASP A 108 | None | 1.38A | 4blvA-4dvgA:undetectable | 4blvA-4dvgA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gaa | MGC78867 PROTEIN (Xenopus laevis) |
PF01433(Peptidase_M1)PF09127(Leuk-A4-hydro_C) | 4 | HIS A 23SER A 158GLU A 162ASP A 180 | None | 1.16A | 4blvA-4gaaA:undetectable | 4blvA-4gaaA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i59 | CYCLOHEXYLAMINEOXIDASE (Microbacteriumoxydans) |
PF01593(Amino_oxidase) | 4 | SER A 405GLU A 386ASP A 391ASP A 403 | None | 1.33A | 4blvA-4i59A:undetectable | 4blvA-4i59A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ig8 | 2'-5'-OLIGOADENYLATESYNTHASE 1 (Homo sapiens) |
PF01909(NTP_transf_2)PF10421(OAS1_C) | 4 | SER A 64GLU A 233ASP A 300ASP A 77 | NoneDTP A 403 ( 4.2A)None MG A 402 (-2.6A) | 1.22A | 4blvA-4ig8A:undetectable | 4blvA-4ig8A:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4keq | 4-PYRIDOXOLACTONASE (Mesorhizobiumjaponicum) |
PF00753(Lactamase_B) | 4 | HIS A 96HIS A 252SER A 251ASP A 170 | ZN A 302 (-3.4A) ZN A 301 ( 3.3A) ZN A 301 ( 4.9A)None | 1.21A | 4blvA-4keqA:undetectable | 4blvA-4keqA:23.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4miv | N-SULPHOGLUCOSAMINESULPHOHYDROLASE (Homo sapiens) |
PF00884(Sulfatase)PF16347(DUF4976) | 4 | HIS A 368HIS A 125SER A 71ASP A 477 | FGP A 70 ( 4.4A)FGP A 70 ( 3.7A)FGP A 70 ( 4.1A)None | 1.38A | 4blvA-4mivA:2.2 | 4blvA-4mivA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nur | PSDSA (Pseudomonas sp.S9) |
PF00753(Lactamase_B)PF14863(Alkyl_sulf_dimr)PF14864(Alkyl_sulf_C) | 4 | HIS A 192HIS A 367SER A 146ASP A 161 | None ZN A 701 (-3.4A)NoneNone | 1.28A | 4blvA-4nurA:undetectable | 4blvA-4nurA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nv0 | 7-METHYLGUANOSINEPHOSPHATE-SPECIFIC5'-NUCLEOTIDASE (Drosophilamelanogaster) |
PF05822(UMPH-1) | 4 | SER A 171GLU A 103ASP A 270ASP A 57 | MGF A 404 (-2.7A)MG7 A 403 (-2.8A)NoneMG7 A 403 (-3.9A) | 1.08A | 4blvA-4nv0A:2.4 | 4blvA-4nv0A:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r27 | GLYCOSIDE HYDROLASE (Microbacteriumsp. Gsoil167) |
PF00232(Glyco_hydro_1) | 4 | HIS A 106HIS A 64GLU A 112ASP A 162 | None | 1.31A | 4blvA-4r27A:undetectable | 4blvA-4r27A:24.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r70 | BACTERIOPHYTOCHROME(LIGHT-REGULATEDSIGNAL TRANSDUCTIONHISTIDINE KINASE),PHYB2 (Rhodopseudomonaspalustris) |
PF00360(PHY)PF01590(GAF)PF08446(PAS_2) | 4 | HIS A 269HIS A 299SER A 297ASP A 190 | BLA A 900 (-3.3A)BLA A 900 (-4.0A)BLA A 900 (-3.2A)None | 1.25A | 4blvA-4r70A:undetectable | 4blvA-4r70A:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u4l | BETA-LACTAMASE NDM-1 (Klebsiellapneumoniae) |
PF00753(Lactamase_B) | 4 | HIS A 120SER A 249ASP A 95ASP A 90 | ZN A 301 (-3.3A) ZN A 302 ( 4.3A)NoneNone | 1.27A | 4blvA-4u4lA:undetectable | 4blvA-4u4lA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uoe | SPERMIDINE SYNTHASE (Plasmodiumfalciparum) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 4 | HIS A 103GLU A 147ASP A 178ASP A 196 | NoneMTA A 401 (-2.7A)MTA A 401 (-3.2A)4ZY A 501 ( 3.6A) | 1.41A | 4blvA-4uoeA:11.2 | 4blvA-4uoeA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uoo | LIPOTEICHOIC ACIDSYNTHASE (Listeriamonocytogenes) |
PF00884(Sulfatase) | 4 | HIS A 261HIS A 482SER A 264ASP A 431 | TPO A 307 ( 4.5A) MG A1645 (-3.2A) MG A1645 ( 3.9A)None | 1.21A | 4blvA-4uooA:2.1 | 4blvA-4uooA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4whn | APXC (Actinobacilluspleuropneumoniae) |
PF02794(HlyC) | 4 | HIS A 152SER A 157GLU A 68ASP A 87 | None | 1.22A | 4blvA-4whnA:undetectable | 4blvA-4whnA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxo | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF00990(GGDEF) | 4 | HIS A 363SER A 442GLU A 403ASP A 464 | None | 1.31A | 4blvA-4wxoA:undetectable | 4blvA-4wxoA:24.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yg7 | SERINE/THREONINE-PROTEIN KINASE HIPA (Escherichiacoli) |
PF07804(HipA_C)PF13657(Couple_hipA) | 4 | HIS D 24SER D 91ASP D 73ASP D 88 | None | 1.32A | 4blvA-4yg7D:undetectable | 4blvA-4yg7D:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ysj | CALMODULIN-LIKEDOMAIN PROTEINKINASE (Eimeria tenella) |
PF00069(Pkinase)PF13499(EF-hand_7) | 4 | HIS A 85SER A 137GLU A 281ASP A 345 | NoneNoneNone CA A 501 (-3.1A) | 0.96A | 4blvA-4ysjA:undetectable | 4blvA-4ysjA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ysl | BETA-LACTAMASEDOMAIN PROTEIN (Pseudomonasputida) |
PF00753(Lactamase_B) | 4 | HIS A 79HIS A 74ASP A 10ASP A 36 | None FE A 301 (-3.4A)NoneNone | 1.40A | 4blvA-4yslA:undetectable | 4blvA-4yslA:24.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bn7 | MALTODEXTRINGLUCOSIDASE (Escherichiacoli) |
PF00128(Alpha-amylase) | 4 | SER A 307GLU A 343ASP A 291ASP A 279 | None | 1.20A | 4blvA-5bn7A:undetectable | 4blvA-5bn7A:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bza | BETA-N-ACETYLHEXOSAMINIDASE (Thermotoganeapolitana) |
PF00933(Glyco_hydro_3) | 4 | HIS A 165SER A 172ASP A 280ASP A 245 | NoneNoneNone CD A 501 (-3.0A) | 1.39A | 4blvA-5bzaA:undetectable | 4blvA-5bzaA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cfa | BONESIALOPROTEIN-BINDINGPROTEIN (Staphylococcusaureus) |
PF10425(SdrG_C_C) | 4 | HIS A 29GLU A 174ASP A 167ASP A 64 | None | 1.34A | 4blvA-5cfaA:undetectable | 4blvA-5cfaA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cuv | ACIDOCALCISOMALPYROPHOSPHATASE (Trypanosomacruzi) |
PF00719(Pyrophosphatase) | 4 | HIS A 202SER A 199GLU A 229ASP A 252 | None | 1.28A | 4blvA-5cuvA:undetectable | 4blvA-5cuvA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ejy | MYOSIN-I HEAVY CHAIN (Dictyosteliumdiscoideum) |
PF00784(MyTH4) | 4 | HIS A 78SER A 100GLU A 140ASP A 88 | None15P A 602 ( 4.3A)NoneNone | 1.32A | 4blvA-5ejyA:undetectable | 4blvA-5ejyA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hp5 | PROTEIN-ARGININEDEIMINASE TYPE-1 (Homo sapiens) |
PF03068(PAD)PF08526(PAD_N)PF08527(PAD_M) | 4 | HIS A 535GLU A 580ASP A 585ASP A 539 | None | 1.38A | 4blvA-5hp5A:undetectable | 4blvA-5hp5A:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k0w | CLASS BCARBAPENEMASE GOB-18 (Elizabethkingiameningoseptica) |
PF00753(Lactamase_B) | 4 | HIS A 241HIS A 175SER A 202ASP A 264 | ZN A 301 (-3.3A) ZN A 302 (-3.3A)NoneNone | 1.30A | 4blvA-5k0wA:undetectable | 4blvA-5k0wA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 4 | HIS A 404HIS A 215SER A 214ASP A 234 | ZN A 511 (-3.1A) ZN A 512 ( 3.3A)NoneNone | 1.38A | 4blvA-5m8tA:undetectable | 4blvA-5m8tA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqs | BETA-L-ARABINOBIOSIDASE (Bacteroidesthetaiotaomicron) |
PF13088(BNR_2) | 4 | HIS A 77SER A 367GLU A 397ASP A 458 | PTR A 372 ( 4.0A)NoneNoneNone | 1.39A | 4blvA-5mqsA:undetectable | 4blvA-5mqsA:13.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n0o | PEPTIDEN-METHYLTRANSFERASE (Omphalotusolearius) |
no annotation | 4 | HIS A 100HIS A 109SER A 108ASP A 45 | None | 1.38A | 4blvA-5n0oA:undetectable | 4blvA-5n0oA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nug | CYTOPLASMIC DYNEIN 1HEAVY CHAIN 1 (Homo sapiens) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | HIS A1810SER A2056GLU A1814ASP A1886 | None | 1.36A | 4blvA-5nugA:undetectable | 4blvA-5nugA:4.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nv8 | EF-P ARGININE 32RHAMNOSYL-TRANSFERASE (Pseudomonasputida) |
PF10093(DUF2331) | 4 | HIS A 32HIS A 371ASP A 274ASP A 364 | NoneNoneTRH A 401 (-4.1A)None | 1.33A | 4blvA-5nv8A:undetectable | 4blvA-5nv8A:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5thm | ESTERASE-6 (Drosophilamelanogaster) |
PF00135(COesterase) | 4 | HIS A 187SER A 214GLU A 318ASP A 448 | 7BZ A 601 ( 4.8A)NoneNoneNone | 1.40A | 4blvA-5thmA:undetectable | 4blvA-5thmA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vjw | RHIZOBIALES-LIKEPHOSPHATASE 2 (Arabidopsisthaliana) |
no annotation | 4 | HIS A 15HIS A 213ASP A 60ASP A 82 | ZN A 402 ( 3.4A) ZN A 401 (-3.4A)NoneNone | 1.11A | 4blvA-5vjwA:undetectable | 4blvA-5vjwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | GUANINENUCLEOTIDE-BINDINGPROTEIN BETASUBUNIT, PUTATIVE (Trichomonasvaginalis) |
no annotation | 4 | HIS g 255SER g 215GLU g 37ASP g 124 | None | 1.29A | 4blvA-5xyig:undetectable | 4blvA-5xyig:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zw4 | PUTATIVEO-METHYLTRANSFERASEYRRM (Bacillussubtilis) |
no annotation | 4 | SER A 68GLU A 85ASP A 113ASP A 133 | SAM A 302 (-2.7A)SAM A 302 (-2.7A)SAM A 302 (-3.3A)SAM A 302 (-3.6A) | 0.93A | 4blvA-5zw4A:12.0 | 4blvA-5zw4A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ax8 | METHIONINE-TRNALIGASE (Mycobacteriumtuberculosis) |
no annotation | 4 | HIS A 51HIS A 99ASP A 129ASP A 49 | NoneNoneNoneME8 A 801 (-4.1A) | 1.31A | 4blvA-6ax8A:undetectable | 4blvA-6ax8A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bog | RNAPOLYMERASE-ASSOCIATED PROTEIN RAPA (Escherichiacoli) |
no annotation | 4 | HIS A 692GLU A 402ASP A 381ASP A 409 | None | 1.20A | 4blvA-6bogA:undetectable | 4blvA-6bogA:undetectable |