SIMILAR PATTERNS OF AMINO ACIDS FOR 4BBO_D_ACTD1113

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h39 SQUALENE--HOPENE
CYCLASE

(Alicyclobacillus
acidocaldarius) 		PF13243
(SQHop_cyclase_C)
PF13249
(SQHop_cyclase_N) 		4 TRP A 591
LEU A 621
LEU A 560
THR A 556
 None
 1.30A 4bboD-1h39A:
undetectable		 4bboD-1h39A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4l CELL DIVISION
PROTEIN KINASE 5
CYCLIN-DEPENDENT
KINASE 5 ACTIVATOR

(Homo sapiens;
Homo sapiens) 		PF00069
(Pkinase)
PF03261
(CDK5_activator) 		4 TRP D 258
LEU A  49
LEU D 232
THR D 228
 None
 1.16A 4bboD-1h4lD:
undetectable		 4bboD-1h4lD:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pd2 HEMATOPOIETIC
PROSTAGLANDIN D
SYNTHASE

(Rattus
norvegicus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TRP 1 153
LEU 1 168
LEU 1 161
THR 1 158
 None
 1.40A 4bboD-1pd21:
0.0		 4bboD-1pd21:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rq1 HYPOTHETICAL 65.0
KDA PROTEIN IN
COX14-COS3
INTERGENIC REGION
PRECURSOR

(Saccharomyces
cerevisiae) 		PF04137
(ERO1) 		4 TRP A 113
LEU A 125
LEU A 243
THR A 245
 None
 1.47A 4bboD-1rq1A:
0.0		 4bboD-1rq1A:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t1u CHOLINE
O-ACETYLTRANSFERASE

(Rattus
norvegicus) 		PF00755
(Carn_acyltransf) 		4 TRP A 253
LEU A 270
LEU A 261
THR A 258
 None
 1.34A 4bboD-1t1uA:
0.0		 4bboD-1t1uA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v40 GLUTATHIONE-REQUIRIN
G PROSTAGLANDIN D
SYNTHASE

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TRP A 153
LEU A 168
LEU A 161
THR A 158
 None
 1.42A 4bboD-1v40A:
0.0		 4bboD-1v40A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2enq PHOSPHATIDYLINOSITOL
-4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT ALPHA
ISOFORM

(Homo sapiens) 		PF00792
(PI3K_C2) 		4 TRP A  60
LEU A 150
LEU A  81
THR A  35
 None
 1.39A 4bboD-2enqA:
0.0		 4bboD-2enqA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h1t HYPOTHETICAL PROTEIN

(Pseudomonas
aeruginosa) 		PF06475
(Glycolipid_bind) 		4 TRP A  53
LEU A  25
LEU A 176
THR A 112
 None
 1.08A 4bboD-2h1tA:
3.6		 4bboD-2h1tA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ifg HIGH AFFINITY NERVE
GROWTH FACTOR
RECEPTOR

(Homo sapiens) 		PF13855
(LRR_8)
PF16920
(TPKR_C2) 		4 TRP A 227
LEU A 213
LEU A 251
THR A 237
 None
 1.42A 4bboD-2ifgA:
0.0		 4bboD-2ifgA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ook HYPOTHETICAL PROTEIN

(Shewanella
frigidimarina) 		PF11964
(SpoIIAA-like) 		4 TRP A 105
LEU A  23
LEU A  41
THR A  38
 None
 1.43A 4bboD-2ookA:
undetectable		 4bboD-2ookA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6g PROGESTERONE
5-BETA-REDUCTASE

(Digitalis
lanata) 		PF01370
(Epimerase) 		4 TRP A 284
LEU A 221
LEU A 310
THR A 238
 None
 1.49A 4bboD-2v6gA:
undetectable		 4bboD-2v6gA:
15.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2y32 BLR5658 PROTEIN

(Bradyrhizobium
japonicum) 		PF01382
(Avidin) 		4 TRP A   5
LEU A  51
LEU A  79
THR A  83
 None
 0.67A 4bboD-2y32A:
19.2		 4bboD-2y32A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ciy TOLL-LIKE RECEPTOR 3

(Mus musculus) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		4 TRP A 452
LEU A 438
LEU A 396
THR A 426
 None
 1.40A 4bboD-3ciyA:
undetectable		 4bboD-3ciyA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cqy ANHYDRO-N-ACETYLMURA
MIC ACID KINASE

(Shewanella
oneidensis) 		PF03702
(AnmK) 		4 TRP A 199
LEU A 256
LEU A 224
THR A 270
 None
 1.13A 4bboD-3cqyA:
undetectable		 4bboD-3cqyA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3go9 INSULINASE FAMILY
PROTEASE

(Yersinia pestis) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 TRP A 101
LEU A 125
LEU A 142
THR A 145
 None
 1.46A 4bboD-3go9A:
undetectable		 4bboD-3go9A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gz8 MUTT/NUDIX FAMILY
PROTEIN

(Shewanella
oneidensis) 		PF00293
(NUDIX) 		4 TRP A 127
LEU A  26
LEU A  73
THR A  77
 None
 1.48A 4bboD-3gz8A:
undetectable		 4bboD-3gz8A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxd FAD-DEPENDENT
PYRIDINE
NUCLEOTIDE-DISULPHID
E OXIDOREDUCTASE

(Novosphingobium
aromaticivorans) 		PF07992
(Pyr_redox_2)
PF14759
(Reductase_C) 		4 TRP A 113
LEU A  91
LEU A 277
THR A 275
 None
 1.44A 4bboD-3lxdA:
undetectable		 4bboD-3lxdA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q60 ROP5B

(Toxoplasma
gondii) 		PF14531
(Kinase-like) 		4 TRP A 215
LEU A 334
LEU A 321
THR A 213
 None
 1.39A 4bboD-3q60A:
undetectable		 4bboD-3q60A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qbw ANHYDRO-N-ACETYLMURA
MIC ACID KINASE

(Pseudomonas
aeruginosa) 		PF03702
(AnmK) 		4 TRP A 193
LEU A 250
LEU A 218
THR A 264
 None
 1.12A 4bboD-3qbwA:
undetectable		 4bboD-3qbwA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)

(Trypanosoma
brucei) 		PF00085
(Thioredoxin)
PF04777
(Evr1_Alr) 		4 TRP A 282
LEU A 268
LEU A 242
THR A 236
 None
 1.42A 4bboD-3qd9A:
undetectable		 4bboD-3qd9A:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rrw THYLAKOID LUMENAL 29
KDA PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00141
(peroxidase) 		4 TRP A 166
LEU A 188
LEU A 206
THR A 202
 None
 1.39A 4bboD-3rrwA:
undetectable		 4bboD-3rrwA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE

(Bacteroides
vulgatus) 		PF13201
(PCMD) 		4 TRP A 162
LEU A 351
LEU A 197
THR A 183
 None
 1.10A 4bboD-3s30A:
undetectable		 4bboD-3s30A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tdu DCN1-LIKE PROTEIN 1

(Homo sapiens) 		PF03556
(Cullin_binding) 		4 TRP A 182
LEU A 200
LEU A 239
THR A 212
 None
 1.44A 4bboD-3tduA:
undetectable		 4bboD-3tduA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uun DYSTROPHIN

(Homo sapiens) 		PF00435
(Spectrin) 		4 TRP A 354
LEU A 389
LEU A 362
THR A 361
 None
 1.40A 4bboD-3uunA:
undetectable		 4bboD-3uunA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uun DYSTROPHIN

(Homo sapiens) 		PF00435
(Spectrin) 		4 TRP A 354
LEU A 434
LEU A 362
THR A 361
 None
 1.41A 4bboD-3uunA:
undetectable		 4bboD-3uunA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0k CULLIN-4A
E3 UBIQUITIN-PROTEIN
LIGASE RBX1

(Homo sapiens;
Mus musculus) 		PF00888
(Cullin)
PF10557
(Cullin_Nedd8)
no annotation 		4 TRP B  27
LEU A 543
LEU A 597
THR A 596
 None
 0.92A 4bboD-4a0kB:
undetectable		 4bboD-4a0kB:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4bbo BLR5658 PROTEIN

(Bradyrhizobium
japonicum) 		PF01382
(Avidin) 		4 TRP A   5
LEU A  51
LEU A  79
THR A  83
 GOL  A1114 (-3.8A)
None
None
GOL  A1114 ( 4.6A)
 0.27A 4bboD-4bboA:
14.9		 4bboD-4bboA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bwi PHYTOCHROME-LIKE
PROTEIN CPH2

(Synechocystis
sp.) 		PF00360
(PHY)
PF01590
(GAF) 		4 TRP A 222
LEU A 414
LEU A 208
THR A 211
 None
 1.47A 4bboD-4bwiA:
undetectable		 4bboD-4bwiA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0x MALONYL-COA
DECARBOXYLASE,
MITOCHONDRIAL

(Homo sapiens) 		PF05292
(MCD)
PF17408
(MCD_N) 		4 TRP A 384
LEU A 398
LEU A 338
THR A 335
 None
 1.27A 4bboD-4f0xA:
undetectable		 4bboD-4f0xA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM)
PF07496
(zf-CW) 		4 TRP A 318
LEU A 367
LEU A 375
THR A 357
 None
 1.34A 4bboD-4hsuA:
undetectable		 4bboD-4hsuA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ljx AT-RICH INTERACTIVE
DOMAIN-CONTAINING
PROTEIN 3A

(Homo sapiens) 		PF01388
(ARID) 		4 TRP A 294
LEU A 275
LEU A 301
THR A 298
 None
 1.43A 4bboD-4ljxA:
undetectable		 4bboD-4ljxA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9d RIK1-ASSOCIATED
FACTOR 1

(Schizosaccharomyces
pombe) 		no annotation 4 TRP B 554
LEU B 575
LEU B 527
THR B 512
 None
 1.18A 4bboD-4o9dB:
undetectable		 4bboD-4o9dB:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pay SIDC, INTERAPTIN

(Legionella
pneumophila) 		no annotation 4 TRP A 323
LEU A 263
LEU A 279
THR A 317
 None
 1.27A 4bboD-4payA:
undetectable		 4bboD-4payA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5

(Homo sapiens) 		PF12348
(CLASP_N) 		4 TRP A1001
LEU A 978
LEU A1009
THR A1008
 None
 0.84A 4bboD-4qmiA:
undetectable		 4bboD-4qmiA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4trg SIDC

(Legionella
pneumophila) 		no annotation 4 TRP A 323
LEU A 263
LEU A 279
THR A 317
 None
 1.22A 4bboD-4trgA:
undetectable		 4bboD-4trgA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u6b CONSERVED
HYPOTHETICAL
LIPOPROTEIN

(Zobellia
galactanivorans) 		PF04616
(Glyco_hydro_43) 		4 TRP A 372
LEU A 374
LEU A  88
THR A 160
 None
 1.46A 4bboD-4u6bA:
undetectable		 4bboD-4u6bA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ykn PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT
ALPHA,PHOSPHATIDYLIN
OSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT ALPHA
ISOFORM FUSION
PROTEIN

(Homo sapiens) 		PF00017
(SH2)
PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
PF02192
(PI3K_p85B)
PF16454
(PI3K_P85_iSH2) 		4 TRP A1383
LEU A1473
LEU A1404
THR A1358
 None
 1.25A 4bboD-4yknA:
undetectable		 4bboD-4yknA:
6.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zds PROTEIN ETHYLENE
INSENSITIVE 3

(Arabidopsis
thaliana) 		PF04873
(EIN3) 		4 TRP A 288
LEU A 178
LEU A 186
THR A 185
 None
 1.47A 4bboD-4zdsA:
undetectable		 4bboD-4zdsA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zuz SIDC

(Legionella
pneumophila) 		no annotation 4 TRP A 324
LEU A 264
LEU A 280
THR A 318
 None
 1.24A 4bboD-4zuzA:
undetectable		 4bboD-4zuzA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a9t PUTATIVE
DEHYDROGENASE

(Amycolatopsis
orientalis) 		PF03446
(NAD_binding_2) 		4 TRP A  34
LEU A  79
LEU A  65
THR A   9
 None
 1.18A 4bboD-5a9tA:
undetectable		 4bboD-5a9tA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dm4 METHYLTRANSFERASE
DOMAIN FAMILY

(Bacillus
pumilus) 		PF13489
(Methyltransf_23) 		4 TRP A 253
LEU A 230
LEU A  54
THR A  55
 None
 1.33A 4bboD-5dm4A:
undetectable		 4bboD-5dm4A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gne LEUCINE
AMINOPEPTIDASE

(Legionella
pneumophila) 		PF04389
(Peptidase_M28) 		4 TRP A 162
LEU A 235
LEU A 170
THR A 169
 None
 1.14A 4bboD-5gneA:
undetectable		 4bboD-5gneA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7e RNA 2',3'-CYCLIC
PHOSPHODIESTERASE

(Deinococcus
radiodurans) 		PF02834
(LigT_PEase) 		4 TRP A 183
LEU A 111
LEU A  56
THR A  53
 None
 1.45A 4bboD-5h7eA:
undetectable		 4bboD-5h7eA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hax NUCLEOPORIN NUP170

(Chaetomium
thermophilum) 		PF08801
(Nucleoporin_N) 		4 TRP A 688
LEU A 763
LEU A 680
THR A 681
 None
 1.13A 4bboD-5haxA:
undetectable		 4bboD-5haxA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j60 THIOREDOXIN
REDUCTASE

(Gloeobacter
violaceus) 		PF07992
(Pyr_redox_2) 		4 TRP A 274
LEU A 305
LEU A  29
THR A  24
 None
 1.49A 4bboD-5j60A:
undetectable		 4bboD-5j60A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m5p PRE-MRNA-SPLICING
HELICASE BRR2

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 TRP A1121
LEU A1022
LEU A1128
THR A1125
 None
 1.25A 4bboD-5m5pA:
undetectable		 4bboD-5m5pA:
5.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nug CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1

(Homo sapiens) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 TRP A4240
LEU A4179
LEU A4223
THR A4226
 None
 1.15A 4bboD-5nugA:
undetectable		 4bboD-5nugA:
2.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vcs ALPHA-1,6-MANNOSYL-G
LYCOPROTEIN
2-BETA-N-ACETYLGLUCO
SAMINYLTRANSFERASE

(Homo sapiens) 		no annotation 4 TRP A 234
LEU A 331
LEU A 353
THR A 349
 None
 1.42A 4bboD-5vcsA:
undetectable		 4bboD-5vcsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vmn BAK PROTEIN

(Singapore
grouper
iridovirus) 		no annotation 4 TRP A 112
LEU A  70
LEU A   9
THR A  19
 NO3  A 206 ( 4.1A)
None
None
None
 1.46A 4bboD-5vmnA:
undetectable		 4bboD-5vmnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eic MYCOBACTERIUM
TUBERCULOSIS
MONOGLYCERIDE LIPASE

(Mycobacterium
tuberculosis) 		no annotation 4 TRP C 274
LEU C 129
LEU C 279
THR C 276
 None
 1.43A 4bboD-6eicC:
undetectable		 4bboD-6eicC:
undetectable