SIMILAR PATTERNS OF AMINO ACIDS FOR 4AZS_A_SAMA1475_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a6d THERMOSOME (BETA
SUBUNIT)

(Thermoplasma
acidophilum) 		PF00118
(Cpn60_TCP1) 		3 ARG B 305
ASP B 230
GLN B 350
 None
 0.92A 4azsA-1a6dB:
undetectable		 4azsA-1a6dB:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3h GUANOSINE
PENTAPHOSPHATE
SYNTHETASE

(Streptomyces
antibioticus) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03726
(PNPase) 		3 ARG A 349
ASP A 520
GLN A 534
 None
 0.80A 4azsA-1e3hA:
undetectable		 4azsA-1e3hA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1he3 BILIVERDIN IX BETA
REDUCTASE

(Homo sapiens) 		PF13460
(NAD_binding_10) 		3 ARG A 140
ASP A 130
GLN A 126
 None
 0.89A 4azsA-1he3A:
5.5		 4azsA-1he3A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hx8 SYNAPSE-ENRICHED
CLATHRIN ADAPTOR
PROTEIN LAP

(Drosophila
melanogaster) 		PF07651
(ANTH) 		3 ARG A 138
ASP A 201
GLN A 198
 SO4  A 301 (-3.6A)
None
None
 0.91A 4azsA-1hx8A:
undetectable		 4azsA-1hx8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum) 		PF13202
(EF-hand_5) 		3 ARG A 105
ASP A 175
GLN A 174
 None
 0.87A 4azsA-1ij5A:
undetectable		 4azsA-1ij5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jt8 PROBABLE TRANSLATION
INITIATION FACTOR 1A

(Methanocaldococcus
jannaschii) 		PF01176
(eIF-1a) 		3 ARG A  34
ASP A  75
GLN A  73
 None
 0.89A 4azsA-1jt8A:
undetectable		 4azsA-1jt8A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k9x M32 CARBOXYPEPTIDASE

(Pyrococcus
furiosus) 		PF02074
(Peptidase_M32) 		3 ARG A 303
ASP A 409
GLN A 408
 None
 0.83A 4azsA-1k9xA:
undetectable		 4azsA-1k9xA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kbl PYRUVATE PHOSPHATE
DIKINASE

([Clostridium]
symbiosum) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		3 ARG A 802
ASP A 374
GLN A 375
 None
 0.65A 4azsA-1kblA:
2.1		 4azsA-1kblA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofc ISWI PROTEIN

(Drosophila
melanogaster) 		PF09110
(HAND)
PF09111
(SLIDE) 		3 ARG X 869
ASP X 826
GLN X 807
 None
 0.92A 4azsA-1ofcX:
undetectable		 4azsA-1ofcX:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pjb L-ALANINE
DEHYDROGENASE

(Phormidium
lapideum) 		PF01262
(AlaDh_PNT_C)
PF05222
(AlaDh_PNT_N) 		3 ARG A  15
ASP A 269
GLN A 270
 None
 0.73A 4azsA-1pjbA:
8.1		 4azsA-1pjbA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9h PROBABLE GTPASE ENGC

(Bacillus
subtilis) 		PF03193
(RsgA_GTPase)
PF16745
(RsgA_N) 		3 ARG A 138
ASP A 128
GLN A 124
 None
 0.83A 4azsA-1t9hA:
undetectable		 4azsA-1t9hA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ulv GLUCODEXTRANASE

(Arthrobacter
globiformis) 		PF00723
(Glyco_hydro_15)
PF09136
(Glucodextran_B)
PF09137
(Glucodextran_N)
PF09985
(Glucodextran_C) 		3 ARG A 662
ASP A 386
GLN A 384
 None
 0.93A 4azsA-1ulvA:
undetectable		 4azsA-1ulvA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uwv 23S RRNA
(URACIL-5-)-METHYLTR
ANSFERASE RUMA

(Escherichia
coli) 		PF01938
(TRAM)
PF05958
(tRNA_U5-meth_tr) 		3 ARG A 366
ASP A  25
GLN A  29
 None
 0.71A 4azsA-1uwvA:
12.2		 4azsA-1uwvA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w5e FTSZ

(Methanocaldococcus
jannaschii) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		3 ARG A 169
ASP A  72
GLN A  74
 GTP  A 500 (-3.5A)
None
None
 0.85A 4azsA-1w5eA:
2.9		 4azsA-1w5eA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wmr ISOPULLULANASE

(Aspergillus
niger) 		PF03718
(Glyco_hydro_49)
PF17433
(Glyco_hydro_49N) 		3 ARG A 405
ASP A 372
GLN A 351
 None
 0.76A 4azsA-1wmrA:
undetectable		 4azsA-1wmrA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ygu LEUKOCYTE COMMON
ANTIGEN

(Homo sapiens) 		PF00102
(Y_phosphatase) 		3 ARG A 930
ASP A1146
GLN A1149
 None
 0.77A 4azsA-1yguA:
undetectable		 4azsA-1yguA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zme PROLINE UTILIZATION
TRANSCRIPTION
ACTIVATOR

(Saccharomyces
cerevisiae) 		PF00172
(Zn_clus) 		3 ARG C  92
ASP C  82
GLN C  78
 None
 0.89A 4azsA-1zmeC:
undetectable		 4azsA-1zmeC:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g28 PYRUVATE
DEHYDROGENASE E1
COMPONENT

(Escherichia
coli) 		PF00456
(Transketolase_N) 		3 ARG A 676
ASP A 770
GLN A 769
 None
 0.79A 4azsA-2g28A:
3.0		 4azsA-2g28A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2huo INOSITOL OXYGENASE

(Mus musculus) 		PF05153
(MIOX) 		3 ARG A  60
ASP A 239
GLN A 238
 None
 0.93A 4azsA-2huoA:
undetectable		 4azsA-2huoA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iv2 FORMATE
DEHYDROGENASE H

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		3 ARG X  68
ASP X 404
GLN X 407
 None
2MD  X 801 (-4.7A)
None
 0.87A 4azsA-2iv2X:
undetectable		 4azsA-2iv2X:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixo SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
ACTIVATOR 1

(Saccharomyces
cerevisiae) 		PF03095
(PTPA) 		3 ARG A 141
ASP A 106
GLN A 129
 None
 0.91A 4azsA-2ixoA:
undetectable		 4azsA-2ixoA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kp7 CROSSOVER JUNCTION
ENDONUCLEASE MUS81

(Mus musculus) 		no annotation 3 ARG A  35
ASP A  90
GLN A  83
 None
 0.72A 4azsA-2kp7A:
undetectable		 4azsA-2kp7A:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdc GLUTAMATE SYNTHASE
[NADPH] SMALL CHAIN

(Azospirillum
brasilense) 		PF07992
(Pyr_redox_2)
PF14691
(Fer4_20) 		3 ARG G  46
ASP G 101
GLN G 331
 None
 0.68A 4azsA-2vdcG:
4.1		 4azsA-2vdcG:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y0m PROBABLE HISTONE
ACETYLTRANSFERASE
MYST1

(Homo sapiens) 		PF01853
(MOZ_SAS) 		3 ARG A 326
ASP A 292
GLN A 294
 None
 0.91A 4azsA-2y0mA:
undetectable		 4azsA-2y0mA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yg6 PUTRESCINE OXIDASE

(Rhodococcus
erythropolis) 		PF01593
(Amino_oxidase) 		3 ARG A  37
ASP A 424
GLN A 431
 FAD  A 600 (-3.8A)
None
None
 0.88A 4azsA-2yg6A:
undetectable		 4azsA-2yg6A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbk TYPE II DNA
TOPOISOMERASE VI
SUBUNIT A

(Sulfolobus
shibatae) 		PF04406
(TP6A_N) 		3 ARG A 242
ASP A 136
GLN A 132
 None
 0.91A 4azsA-2zbkA:
undetectable		 4azsA-2zbkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ag6 PANTOTHENATE
SYNTHETASE

(Staphylococcus
aureus) 		PF02569
(Pantoate_ligase) 		3 ARG A  43
ASP A  79
GLN A  75
 None
 0.92A 4azsA-3ag6A:
undetectable		 4azsA-3ag6A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3apm PROTEIN-ARGININE
DEIMINASE TYPE-4

(Homo sapiens) 		PF03068
(PAD)
PF08526
(PAD_N)
PF08527
(PAD_M) 		3 ARG A 156
ASP A 179
GLN A 178
 None
 0.74A 4azsA-3apmA:
undetectable		 4azsA-3apmA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c0k UPF0064 PROTEIN YCCW

(Escherichia
coli) 		PF10672
(Methyltrans_SAM) 		3 ARG A 212
ASP A 118
GLN A 127
 None
 0.83A 4azsA-3c0kA:
13.6		 4azsA-3c0kA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgx PUTATIVE
NUCLEOTIDE-DIPHOSPHO
-SUGAR TRANSFERASE

(Desulfovibrio
alaskensis) 		PF09837
(DUF2064) 		3 ARG A 219
ASP A  41
GLN A  40
 None
 0.82A 4azsA-3cgxA:
undetectable		 4azsA-3cgxA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csv AMINOGLYCOSIDE
PHOSPHOTRANSFERASE

(Ruegeria sp.
TM1040) 		PF01636
(APH) 		3 ARG A   4
ASP A  57
GLN A  59
 None
None
ZN  A 333 ( 4.0A)
 0.85A 4azsA-3csvA:
3.3		 4azsA-3csvA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cym UNCHARACTERIZED
PROTEIN BAD_0989

(Bifidobacterium
adolescentis) 		PF00570
(HRDC)
PF01612
(DNA_pol_A_exo1) 		3 ARG A 415
ASP A  98
GLN A 101
 GOL  A 503 (-3.0A)
None
None
 0.92A 4azsA-3cymA:
undetectable		 4azsA-3cymA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dbg PUTATIVE CYTOCHROME
P450

(Streptomyces
coelicolor) 		PF00067
(p450) 		3 ARG A 371
ASP A 292
GLN A 435
 None
 0.85A 4azsA-3dbgA:
undetectable		 4azsA-3dbgA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos taurus) 		PF13472
(Lipase_GDSL_2) 		3 ARG A  29
ASP A  20
GLN A  18
 None
 0.92A 4azsA-3dt8A:
3.4		 4azsA-3dt8A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e8j COPROPORPHYRINOGEN
III OXIDASE

(Leishmania
naiffi) 		PF01218
(Coprogen_oxidas) 		3 ARG A 238
ASP A  27
GLN A  29
 None
 0.91A 4azsA-3e8jA:
undetectable		 4azsA-3e8jA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f2b DNA-DIRECTED DNA
POLYMERASE III ALPHA
CHAIN

(Geobacillus
kaustophilus) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		3 ARG A 985
ASP A1113
GLN A1112
 PO4  A   1 (-3.8A)
None
None
 0.75A 4azsA-3f2bA:
undetectable		 4azsA-3f2bA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhh OUTER MEMBRANE HEME
RECEPTOR SHUA

(Shigella
dysenteriae) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 ARG A 296
ASP A 248
GLN A 246
 None
 0.87A 4azsA-3fhhA:
undetectable		 4azsA-3fhhA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhn PROTEIN TRANSPORT
PROTEIN TIP20

(Saccharomyces
cerevisiae) 		PF04437
(RINT1_TIP1) 		3 ARG A 568
ASP A 620
GLN A 616
 None
 0.93A 4azsA-3fhnA:
undetectable		 4azsA-3fhnA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gde DNA LIGASE

(Archaeoglobus
fulgidus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		3 ARG A 411
ASP A 296
GLN A 256
 PO4  A 556 (-2.9A)
None
None
 0.92A 4azsA-3gdeA:
undetectable		 4azsA-3gdeA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gme POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Escherichia
coli) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		3 ARG A 325
ASP A 492
GLN A 506
 None
MN  A 550 (-3.6A)
None
 0.91A 4azsA-3gmeA:
undetectable		 4azsA-3gmeA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL

(Bos taurus;
Bos taurus) 		PF00318
(Ribosomal_S2)
PF00380
(Ribosomal_S9) 		3 ARG B 136
ASP I 217
GLN I 216
 A  A 644 ( 3.7A)
A  A 641 ( 3.1A)
A  A 641 ( 3.7A)
 0.89A 4azsA-3jd5B:
undetectable		 4azsA-3jd5B:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfw UNCHARACTERIZED
PROTEIN

(Mycobacterium
tuberculosis) 		PF07848
(PaaX)
PF08223
(PaaX_C) 		3 ARG X 231
ASP X  75
GLN X  74
 None
 0.87A 4azsA-3kfwX:
undetectable		 4azsA-3kfwX:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kh5 PROTEIN MJ1225

(Methanocaldococcus
jannaschii) 		PF00571
(CBS) 		3 ARG A 181
ASP A 135
GLN A  10
 ADP  A 284 ( 3.5A)
ADP  A 281 (-2.6A)
ADP  A 281 (-2.9A)
 0.63A 4azsA-3kh5A:
undetectable		 4azsA-3kh5A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mes CHOLINE KINASE

(Cryptosporidium
parvum) 		PF01633
(Choline_kinase) 		3 ARG A 108
ASP A 268
GLN A 270
 ADP  A 425 (-2.6A)
PT3  A 428 ( 2.4A)
PT3  A 428 (-3.6A)
 0.87A 4azsA-3mesA:
3.5		 4azsA-3mesA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n05 NH(3)-DEPENDENT
NAD(+) SYNTHETASE

(Streptomyces
avermitilis) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		3 ARG A 203
ASP A 230
GLN A 246
 None
 0.93A 4azsA-3n05A:
3.9		 4azsA-3n05A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3njp EPIDERMAL GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV) 		3 ARG A 497
ASP A 369
GLN A 366
 None
 0.91A 4azsA-3njpA:
undetectable		 4azsA-3njpA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nz4 PHENYLALANINE
AMMONIA-LYASE

(Taxus
canadensis) 		PF00221
(Lyase_aromatic) 		3 ARG A 664
ASP A 652
GLN A 647
 None
 0.75A 4azsA-3nz4A:
undetectable		 4azsA-3nz4A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogg BOTULINUM NEUROTOXIN
TYPE D

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		3 ARG A1082
ASP A1059
GLN A 873
 None
 0.76A 4azsA-3oggA:
undetectable		 4azsA-3oggA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r89 OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Anaerococcus
prevotii) 		PF00215
(OMPdecase) 		3 ARG A 152
ASP A 230
GLN A 227
 None
 0.74A 4azsA-3r89A:
undetectable		 4azsA-3r89A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rha PUTRESCINE OXIDASE

(Paenarthrobacter
aurescens) 		PF01593
(Amino_oxidase) 		3 ARG A  39
ASP A 425
GLN A 432
 FDA  A 483 (-3.9A)
None
None
 0.88A 4azsA-3rhaA:
undetectable		 4azsA-3rhaA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t24 PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		3 ARG A  19
ASP A 157
GLN A 155
 None
 0.69A 4azsA-3t24A:
undetectable		 4azsA-3t24A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE

(Sinorhizobium
meliloti) 		PF00106
(adh_short) 		3 ARG A 135
ASP A  75
GLN A  71
 None
 0.92A 4azsA-3u9lA:
5.4		 4azsA-3u9lA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE

(Oryza sativa) 		PF00875
(DNA_photolyase) 		3 ARG A 272
ASP A 446
GLN A 447
 None
None
EDO  A 703 (-4.7A)
 0.82A 4azsA-3umvA:
undetectable		 4azsA-3umvA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vse PUTATIVE
UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF10672
(Methyltrans_SAM) 		3 ARG A 205
ASP A 116
GLN A 125
 None
 0.81A 4azsA-3vseA:
13.3		 4azsA-3vseA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wxo CATALASE-PEROXIDASE

(Synechococcus
elongatus) 		PF00141
(peroxidase) 		3 ARG A 352
ASP A 322
GLN A 320
 None
NA  A 806 (-2.4A)
None
 0.90A 4azsA-3wxoA:
undetectable		 4azsA-3wxoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdn MONOAMINE OXIDASE N

(Aspergillus
niger) 		PF01593
(Amino_oxidase) 		3 ARG A  71
ASP A 392
GLN A 390
 FAD  A1487 (-4.3A)
None
None
 0.80A 4azsA-3zdnA:
2.3		 4azsA-3zdnA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria;
Sus scrofa) 		PF00063
(Myosin_head)
PF01353
(GFP) 		3 ARG A 667
ASP A 510
GLN A 512
 None
 0.84A 4azsA-4anjA:
undetectable		 4azsA-4anjA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4asi ACETYL-COA
CARBOXYLASE 1

(Homo sapiens) 		PF01039
(Carboxyl_trans) 		3 ARG A1750
ASP A2069
GLN A2065
 None
 0.90A 4azsA-4asiA:
undetectable		 4azsA-4asiA:
21.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4azv WBDD

(Escherichia
coli) 		PF00069
(Pkinase)
PF13847
(Methyltransf_31) 		3 ARG A  36
ASP A  82
GLN A  84
 SAM  A1474 ( 3.1A)
SAM  A1474 (-1.7A)
SAM  A1474 (-3.9A)
 0.03A 4azsA-4azvA:
57.8		 4azsA-4azvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4azw WBDD

(Escherichia
coli) 		PF00069
(Pkinase)
PF13847
(Methyltransf_31) 		3 ARG A  36
ASP A  82
GLN A  84
 SAM  A1451 (-3.2A)
SAM  A1451 (-2.7A)
SAM  A1451 (-4.2A)
 0.37A 4azsA-4azwA:
49.3		 4azsA-4azwA:
99.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bum VOLTAGE-DEPENDENT
ANION CHANNEL 2

(Danio rerio) 		PF01459
(Porin_3) 		3 ARG X 218
ASP X 186
GLN X 166
 None
 0.89A 4azsA-4bumX:
undetectable		 4azsA-4bumX:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cw5 DFNA

(Bacillus
velezensis) 		PF03060
(NMO) 		3 ARG A 726
ASP A 585
GLN A 584
 None
 0.84A 4azsA-4cw5A:
undetectable		 4azsA-4cw5A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dwq TRNA-SPLICING LIGASE
RTCB

(Pyrococcus
horikoshii) 		PF01139
(RtcB) 		3 ARG A 250
ASP A 265
GLN A  46
 None
 0.83A 4azsA-4dwqA:
undetectable		 4azsA-4dwqA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hri HETEROCYST
DIFFERENTIATION
CONTROL PROTEIN

(Nostoc sp. PCC
7120) 		no annotation 3 ARG B 223
ASP B 270
GLN B 267
 None
 0.92A 4azsA-4hriB:
undetectable		 4azsA-4hriB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i2w PROTEIN UNC-45

(Caenorhabditis
elegans) 		PF11701
(UNC45-central) 		3 ARG A 221
ASP A 271
GLN A 273
 None
 0.91A 4azsA-4i2wA:
undetectable		 4azsA-4i2wA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jxt REGULATION OF
NUCLEAR PRE-MRNA
DOMAIN-CONTAINING
PROTEIN 1A

(Homo sapiens) 		PF04818
(CTD_bind) 		3 ARG A 106
ASP A  65
GLN A  24
 None
UNX  A 205 (-2.9A)
UNX  A 205 ( 4.7A)
 0.82A 4azsA-4jxtA:
undetectable		 4azsA-4jxtA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k1p NHEA

(Bacillus cereus) 		PF05791
(Bacillus_HBL) 		3 ARG A  87
ASP A 137
GLN A 136
 None
 0.57A 4azsA-4k1pA:
undetectable		 4azsA-4k1pA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mpt PUTATIVE
LEU/ILE/VAL-BINDING
PROTEIN

(Bordetella
pertussis) 		PF13458
(Peripla_BP_6) 		3 ARG A 284
ASP A 214
GLN A 186
 None
 0.91A 4azsA-4mptA:
3.1		 4azsA-4mptA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ox0 DEVELOPMENTAL
PROTEIN SEPALLATA 3

(Arabidopsis
thaliana) 		PF01486
(K-box) 		3 ARG A  88
ASP A  78
GLN A  74
 None
 0.93A 4azsA-4ox0A:
undetectable		 4azsA-4ox0A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p2b GLUTAMINE
AMINOACYL-TRNA
SYNTHETASE

(Toxoplasma
gondii) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		3 ARG A 414
ASP A 401
GLN A 359
 None
 0.92A 4azsA-4p2bA:
undetectable		 4azsA-4p2bA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pau NITROGEN REGULATORY
PROTEIN A

(Staphylococcus
aureus) 		PF13185
(GAF_2) 		3 ARG A 125
ASP A  17
GLN A  13
 None
 0.82A 4azsA-4pauA:
undetectable		 4azsA-4pauA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxl CYTOSOLIC ALDEHYDE
DEHYDROGENASE RF2C

(Zea mays) 		PF00171
(Aldedh) 		3 ARG A 356
ASP A 347
GLN A 197
 None
None
NAD  A 601 (-4.2A)
 0.87A 4azsA-4pxlA:
5.3		 4azsA-4pxlA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2

(Erythrobacter
litoralis) 		PF07568
(HisKA_2)
PF13426
(PAS_9)
PF13581
(HATPase_c_2) 		3 ARG A  37
ASP A 216
GLN A 253
 None
None
ANP  A 401 ( 4.3A)
 0.82A 4azsA-4r3aA:
undetectable		 4azsA-4r3aA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s28 PHOSPHOMETHYLPYRIMID
INE SYNTHASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF01964
(ThiC_Rad_SAM) 		3 ARG A 587
ASP A 527
GLN A 523
 None
 0.93A 4azsA-4s28A:
undetectable		 4azsA-4s28A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upl SULFATASE FAMILY
PROTEIN

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		3 ARG A 101
ASP A   9
GLN A  10
 None
ZN  A1553 (-2.2A)
None
 0.58A 4azsA-4uplA:
undetectable		 4azsA-4uplA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzs BETA-GALACTOSIDASE

(Bifidobacterium
bifidum) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		3 ARG A 397
ASP A 387
GLN A 383
 None
 0.85A 4azsA-4uzsA:
undetectable		 4azsA-4uzsA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 3
ORIGIN RECOGNITION
COMPLEX SUBUNIT 5

(Drosophila
melanogaster;
Drosophila
melanogaster) 		PF07034
(ORC3_N)
PF13191
(AAA_16)
PF14630
(ORC5_C) 		3 ARG E 132
ASP C 222
GLN C 221
 None
 0.87A 4azsA-4xgcE:
undetectable		 4azsA-4xgcE:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xr7 PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2

(Saccharomyces
cerevisiae) 		no annotation 3 ARG G 481
ASP G 924
GLN G 926
 None
 0.93A 4azsA-4xr7G:
undetectable		 4azsA-4xr7G:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yh7 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE DELTA

(Mus musculus) 		PF00041
(fn3)
PF07679
(I-set)
PF13927
(Ig_3) 		3 ARG A 181
ASP A  83
GLN A  53
 None
 0.83A 4azsA-4yh7A:
undetectable		 4azsA-4yh7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cov NAEGLERIA GRUBERI
RNA LIGASE

(Naegleria
gruberi) 		PF09414
(RNA_ligase) 		3 ARG A 149
ASP A 172
GLN A 234
 None
 0.77A 4azsA-5covA:
undetectable		 4azsA-5covA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dl7 PORIN

(Acinetobacter
baumannii) 		PF03573
(OprD) 		3 ARG A  19
ASP A 158
GLN A 156
 None
 0.77A 4azsA-5dl7A:
undetectable		 4azsA-5dl7A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gkq ALYGC MUTANT - R241A

(Paraglaciecola
chathamensis) 		PF14592
(Chondroitinas_B) 		3 ARG A 393
ASP A 350
GLN A 351
 None
 0.66A 4azsA-5gkqA:
undetectable		 4azsA-5gkqA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h42 UNCHARACTERIZED
PROTEIN

(Lachnoclostridium
phytofermentans) 		PF17167
(Glyco_hydro_36) 		3 ARG A 907
ASP A 631
GLN A 634
 None
G1P  A1201 (-2.8A)
None
 0.75A 4azsA-5h42A:
undetectable		 4azsA-5h42A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hmp UNCONVENTIONAL
MYOSIN-VC

(Homo sapiens) 		PF00063
(Myosin_head) 		3 ARG A 648
ASP A 489
GLN A 491
 None
 0.72A 4azsA-5hmpA:
undetectable		 4azsA-5hmpA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6g ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN,ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01039
(Carboxyl_trans)
PF08326
(ACC_central) 		3 ARG A1663
ASP A1979
GLN A1975
 None
 0.86A 4azsA-5i6gA:
undetectable		 4azsA-5i6gA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01039
(Carboxyl_trans)
PF08326
(ACC_central) 		3 ARG A1663
ASP A1979
GLN A1975
 None
 0.79A 4azsA-5i6hA:
undetectable		 4azsA-5i6hA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6i ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN,ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN,ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01039
(Carboxyl_trans)
PF08326
(ACC_central) 		3 ARG A1663
ASP A1979
GLN A1975
 None
 0.86A 4azsA-5i6iA:
undetectable		 4azsA-5i6iA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iqp 14-3-3 PROTEIN THETA

(Homo sapiens) 		PF00244
(14-3-3) 		3 ARG A  91
ASP A  81
GLN A  77
 None
 0.86A 4azsA-5iqpA:
undetectable		 4azsA-5iqpA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ixm LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Yersinia
pestis;
Yersinia pestis) 		PF04453
(OstA_C)
PF04390
(LptE) 		3 ARG B 128
ASP A 170
GLN A 168
 None
 0.91A 4azsA-5ixmB:
undetectable		 4azsA-5ixmB:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j90 RAGB/SUSD DOMAIN
PROTEIN

(Flavobacterium
johnsoniae) 		PF12741
(SusD-like) 		3 ARG A 386
ASP A  76
GLN A  71
 None
 0.90A 4azsA-5j90A:
undetectable		 4azsA-5j90A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kdx METALLOPEPTIDASE

(Pseudomonas
aeruginosa) 		PF13402
(Peptidase_M60) 		3 ARG A 863
ASP A 912
GLN A 915
 None
 0.73A 4azsA-5kdxA:
undetectable		 4azsA-5kdxA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mdq CHITOPORIN

(Vibrio harveyi) 		no annotation 3 ARG A 154
ASP A 200
GLN A 226
 None
 0.84A 4azsA-5mdqA:
undetectable		 4azsA-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nji PHTHIOCEROL/PHENOLPH
THIOCEROL SYNTHESIS
POLYKETIDE SYNTHASE
TYPE I PPSC

(Mycobacterium
tuberculosis) 		PF14765
(PS-DH) 		3 ARG A1105
ASP A1200
GLN A1204
 None
 0.92A 4azsA-5njiA:
undetectable		 4azsA-5njiA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u04 ZIKA VIRUS NS5 RDRP

(Zika virus) 		PF00972
(Flavi_NS5) 		3 ARG A 647
ASP A 635
GLN A 634
 None
 0.73A 4azsA-5u04A:
undetectable		 4azsA-5u04A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r DNA-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08163
(NUC194) 		3 ARG C2842
ASP C2860
GLN C2859
 None
 0.91A 4azsA-5y3rC:
undetectable		 4azsA-5y3rC:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6r GENOME POLYPROTEIN

(Pestivirus C) 		no annotation 3 ARG A 111
ASP A 161
GLN A 159
 SO4  A 702 ( 3.6A)
None
None
 0.66A 4azsA-5y6rA:
undetectable		 4azsA-5y6rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b9s METHYLPHOSPHONATE
SYNTHASE

(Nitrosopumilus
maritimus) 		no annotation 3 ARG A 195
ASP A 317
GLN A 318
 None
 0.85A 4azsA-6b9sA:
undetectable		 4azsA-6b9sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Acinetobacter
baumannii) 		no annotation 3 ARG A 327
ASP A 494
GLN A 508
 None
 0.86A 4azsA-6d6kA:
undetectable		 4azsA-6d6kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dd6 PHOTOLYASE PHRB

(Agrobacterium
tumefaciens) 		no annotation 3 ARG A 476
ASP A 254
GLN A 253
 None
 0.82A 4azsA-6dd6A:
2.2		 4azsA-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33

(Homo sapiens;
Homo sapiens) 		no annotation
no annotation 		3 ARG B  74
ASP A 205
GLN A 207
 None
 0.79A 4azsA-6f9nB:
undetectable		 4azsA-6f9nB:
undetectable