SIMILAR PATTERNS OF AMINO ACIDS FOR 4AMJ_B_CVDB1360_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 VAL A 114
ASP A 192
TYR A 199
TRP A 313
 ERC  A1201 (-3.8A)
ERC  A1201 (-4.2A)
None
ERC  A1201 (-4.4A)
 0.47A 4amjB-3pdsA:
38.4		 4amjB-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gbr BETA-2 ADRENERGIC
RECEPTOR

(Homo sapiens) 		PF00001
(7tm_1) 		4 VAL A 114
ASP A 192
TYR A 199
TRP A 285
 CAU  A 500 (-3.5A)
None
None
None
 0.52A 4amjB-4gbrA:
39.4		 4amjB-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 VAL A1114
ASP A1192
TYR A1199
TRP A1313
 P0G  A1401 (-3.7A)
None
None
1WV  A1403 ( 4.3A)
 0.97A 4amjB-4ldeA:
33.0		 4amjB-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5f8u BETA-1 ADRENERGIC
RECEPTOR

(Meleagris
gallopavo) 		no annotation 4 VAL B 122
ASP B 200
TYR B 207
TRP B 330
 P32  B 400 (-3.5A)
None
None
None
 0.58A 4amjB-5f8uB:
40.2		 4amjB-5f8uB:
99.37