SIMILAR PATTERNS OF AMINO ACIDS FOR 4ACB_C_DXCC1477

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a97 XANTHINE-GUANINE
PHOSPHORIBOSYLTRANSF
ERASE

(Escherichia
coli) 		PF00156
(Pribosyltran) 		4 GLY A  43
ARG A  53
ILE A  32
LEU A  19
 None
 0.85A 4acbC-1a97A:
undetectable		 4acbC-1a97A:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dhs DEOXYHYPUSINE
SYNTHASE

(Homo sapiens) 		PF01916
(DS) 		4 THR A 130
GLY A 102
ILE A 290
LEU A 128
 None
 1.04A 4acbC-1dhsA:
undetectable		 4acbC-1dhsA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hjv CHITINASE-3 LIKE
PROTEIN 1

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		4 GLY A 262
ARG A 310
ILE A 299
LEU A 356
 None
None
None
NAG  A  -2 (-4.9A)
 0.90A 4acbC-1hjvA:
3.0		 4acbC-1hjvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j0n XANTHAN LYASE

(Bacillus sp.
GL1) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 GLY A 205
ARG A 101
ILE A 202
LEU A 270
 None
 1.05A 4acbC-1j0nA:
undetectable		 4acbC-1j0nA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j8m SIGNAL RECOGNITION
54 KDA PROTEIN

(Acidianus
ambivalens) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 THR F 113
GLY F 116
ILE F 152
LEU F 281
 None
 0.99A 4acbC-1j8mF:
3.1		 4acbC-1j8mF:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7h ALKALINE PHOSPHATASE

(Pandalus
borealis) 		PF00245
(Alk_phosphatase) 		4 THR A 271
GLY A 203
ARG A 162
LEU A 273
 SO4  A 483 ( 4.5A)
None
None
None
 0.93A 4acbC-1k7hA:
undetectable		 4acbC-1k7hA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lml LEISHMANOLYSIN

(Leishmania
major) 		PF01457
(Peptidase_M8) 		4 THR A 229
GLY A 241
ILE A 243
LEU A 270
 None
 1.01A 4acbC-1lmlA:
undetectable		 4acbC-1lmlA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1los OROTIDINE
MONOPHOSPHATE
DECARBOXYLASE

(Methanothermobacter
thermautotrophicus) 		PF00215
(OMPdecase) 		4 GLY A 156
ARG A   5
ILE A 178
LEU A 123
 None
 1.01A 4acbC-1losA:
3.1		 4acbC-1losA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o9b HYPOTHETICAL
SHIKIMATE
5-DEHYDROGENASE-LIKE
PROTEIN YDIB

(Escherichia
coli) 		PF08501
(Shikimate_dh_N) 		4 THR A 137
GLY A 140
ILE A 151
LEU A  87
 None
 0.91A 4acbC-1o9bA:
3.1		 4acbC-1o9bA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o9y HRCQ2

(Pseudomonas
syringae) 		PF01052
(FliMN_C) 		4 THR A  53
GLY A  64
ILE A  77
LEU A  21
 None
 0.99A 4acbC-1o9yA:
undetectable		 4acbC-1o9yA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pyf IOLS PROTEIN

(Bacillus
subtilis) 		PF00248
(Aldo_ket_red) 		4 THR A  54
GLY A  19
ILE A 277
LEU A  52
 None
 0.98A 4acbC-1pyfA:
3.0		 4acbC-1pyfA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
HUMAN RHINOVIRUS 3
COAT PROTEIN

(Rhinovirus B;
Rhinovirus B) 		PF00073
(Rhv)
PF00073
(Rhv) 		4 THR 1  42
GLY 1  40
ILE 2  32
LEU 2 182
 None
 0.90A 4acbC-1rhi1:
undetectable		 4acbC-1rhi1:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s4f RNA-DEPENDENT RNA
POLYMERASE

(Pestivirus A) 		PF00998
(RdRP_3) 		4 THR A 410
GLY A 413
ILE A 361
LYS A 475
 None
 1.07A 4acbC-1s4fA:
undetectable		 4acbC-1s4fA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t8b PHOSPHATE TRANSPORT
SYSTEM PROTEIN PHOU
HOMOLOG

(Aquifex
aeolicus) 		PF01895
(PhoU) 		4 GLY A  98
ARG A 192
ILE A 197
LEU A  94
 None
 0.94A 4acbC-1t8bA:
undetectable		 4acbC-1t8bA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tjy SUGAR TRANSPORT
PROTEIN

(Salmonella
enterica) 		PF13407
(Peripla_BP_4) 		4 THR A 303
ARG A 327
ILE A 128
LEU A 294
 None
 1.03A 4acbC-1tjyA:
4.6		 4acbC-1tjyA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uh9 HIZOPUSPEPSIN I

(Rhizopus
microsporus) 		PF00026
(Asp) 		4 THR A 219
GLY A 300
ILE A 298
LEU A 217
 None
 0.79A 4acbC-1uh9A:
undetectable		 4acbC-1uh9A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1up4 6-PHOSPHO-BETA-GLUCO
SIDASE

(Thermotoga
maritima) 		PF02056
(Glyco_hydro_4)
PF11975
(Glyco_hydro_4C) 		4 THR A 104
GLY A 106
ARG A 243
ILE A 100
 None
 1.04A 4acbC-1up4A:
4.4		 4acbC-1up4A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vzy 33 KDA CHAPERONIN

(Bacillus
subtilis) 		PF01430
(HSP33) 		4 THR A 112
GLY A  68
ARG A  44
ILE A  66
 None
 1.02A 4acbC-1vzyA:
undetectable		 4acbC-1vzyA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wle SERYL-TRNA
SYNTHETASE

(Bos taurus) 		PF00587
(tRNA-synt_2b) 		4 THR A 432
GLY A 338
ILE A 303
LEU A 287
 None
 0.94A 4acbC-1wleA:
undetectable		 4acbC-1wleA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xqm KINDLING FLUORESCENT
PROTEIN

(Anemonia
sulcata) 		PF01353
(GFP) 		4 THR A  14
GLY A  28
ILE A  43
LYS A  66
 None
None
None
CH6  A  63 ( 3.5A)
 1.01A 4acbC-1xqmA:
undetectable		 4acbC-1xqmA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bp1 AFLATOXIN B1
ALDEHYDE REDUCTASE
MEMBER 2

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		4 THR A  74
GLY A  44
ILE A 315
LEU A  72
 None
NDP  A1361 (-3.1A)
NDP  A1361 (-3.6A)
None
 1.05A 4acbC-2bp1A:
2.2		 4acbC-2bp1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c91 AFLATOXIN B1
ALDEHYDE REDUCTASE
MEMBER 2

(Mus musculus) 		PF00248
(Aldo_ket_red) 		4 THR A  41
GLY A  11
ILE A 282
LEU A  39
 None
NAP  A 350 (-3.1A)
NAP  A 350 (-3.6A)
None
 1.02A 4acbC-2c91A:
3.1		 4acbC-2c91A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dhn 7,8-DIHYDRONEOPTERIN
ALDOLASE

(Staphylococcus
aureus) 		PF02152
(FolB) 		4 THR A  34
ARG A 118
ILE A  84
LEU A   7
 None
 0.94A 4acbC-2dhnA:
undetectable		 4acbC-2dhnA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eba PUTATIVE
GLUTARYL-COA
DEHYDROGENASE

(Thermus
thermophilus) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 THR A 132
GLY A 130
ARG A 147
ILE A 175
 FAD  A1001 (-3.2A)
FAD  A1001 ( 4.6A)
None
None
 1.07A 4acbC-2ebaA:
undetectable		 4acbC-2ebaA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fqx MEMBRANE LIPOPROTEIN
TMPC

(Treponema
pallidum) 		PF02608
(Bmp) 		4 THR A 256
GLY A 236
ARG A 226
ILE A 219
 None
 0.98A 4acbC-2fqxA:
5.1		 4acbC-2fqxA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fv0 UNSATURATED
GLUCURONYL HYDROLASE

(Bacillus sp.
GL1) 		PF07470
(Glyco_hydro_88) 		4 GLY A 288
ARG A 251
ILE A 227
LEU A 232
 None
 1.04A 4acbC-2fv0A:
undetectable		 4acbC-2fv0A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g02 NISIN BIOSYNTHESIS
PROTEIN NISC

(Lactococcus
lactis) 		PF05147
(LANC_like) 		4 THR A  41
GLY A 377
ILE A  46
LEU A  39
 None
 1.04A 4acbC-2g02A:
undetectable		 4acbC-2g02A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ged SIGNAL RECOGNITION
PARTICLE RECEPTOR
BETA SUBUNIT

(Saccharomyces
cerevisiae) 		PF09439
(SRPRB) 		4 THR A  52
GLY A  50
ARG A 237
ILE A 228
 SO4  A 401 (-3.8A)
SO4  A 401 (-3.3A)
None
None
 0.92A 4acbC-2gedA:
5.0		 4acbC-2gedA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gzm GLUTAMATE RACEMASE

(Bacillus
anthracis) 		PF01177
(Asp_Glu_race) 		4 GLY A 117
ARG A  48
ILE A 119
LEU A 143
 None
 1.05A 4acbC-2gzmA:
2.9		 4acbC-2gzmA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lcq PUTATIVE TOXIN VAPC6

(Pyrococcus
horikoshii) 		PF17146
(PIN_6) 		4 THR A   8
GLY A  24
ILE A  22
LEU A   5
 None
 0.92A 4acbC-2lcqA:
undetectable		 4acbC-2lcqA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mng POTASSIUM/SODIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 4

(Homo sapiens) 		PF00027
(cNMP_binding) 		4 THR A 665
GLY A 629
ILE A 623
LEU A 663
 None
 0.96A 4acbC-2mngA:
undetectable		 4acbC-2mngA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ox4 PUTATIVE MANDELATE
RACEMASE

(Zymomonas
mobilis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 THR A 291
GLY A 293
ILE A 301
LEU A 289
 None
 0.98A 4acbC-2ox4A:
2.3		 4acbC-2ox4A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5z TYPE VI SECRETION
SYSTEM COMPONENT

(Escherichia
coli) 		PF05954
(Phage_GPD) 		4 THR X 344
ARG X  83
ILE X 326
LEU X 311
 None
 0.92A 4acbC-2p5zX:
2.4		 4acbC-2p5zX:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pop MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE
7-INTERACTING
PROTEIN 1

(Homo sapiens) 		PF00481
(PP2C) 		4 GLY A 274
ARG A 104
ILE A 272
LEU A 178
 None
 1.00A 4acbC-2popA:
undetectable		 4acbC-2popA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q2l SUPEROXIDE DISMUTASE

(Potentilla
atrosanguinea) 		PF00080
(Sod_Cu) 		4 THR A  21
GLY A   4
ILE A 148
LEU A  19
 None
 0.99A 4acbC-2q2lA:
undetectable		 4acbC-2q2lA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qwt TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Mycolicibacterium
vanbaalenii) 		PF00440
(TetR_N) 		4 THR A 128
GLY A 130
ILE A 151
LEU A 126
 None
 1.06A 4acbC-2qwtA:
undetectable		 4acbC-2qwtA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vg2 UNDECAPRENYL
PYROPHOSPHATE
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF01255
(Prenyltransf) 		4 THR A  90
GLY A  92
ARG A 145
LEU A  87
 None
 0.99A 4acbC-2vg2A:
undetectable		 4acbC-2vg2A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x40 BETA-GLUCOSIDASE

(Thermotoga
neapolitana) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 THR A 363
GLY A 359
ILE A 404
LEU A 382
 None
 1.03A 4acbC-2x40A:
undetectable		 4acbC-2x40A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xio PUTATIVE
DEOXYRIBONUCLEASE
TATDN1

(Homo sapiens) 		PF01026
(TatD_DNase) 		4 GLY A  75
ARG A 167
ILE A 110
LEU A  99
 None
 0.83A 4acbC-2xioA:
3.2		 4acbC-2xioA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwu IMPORTIN13

(Homo sapiens) 		PF03810
(IBN_N)
PF08389
(Xpo1) 		4 THR B 304
GLY B 307
ILE B 311
LEU B 293
 None
 1.02A 4acbC-2xwuB:
undetectable		 4acbC-2xwuB:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zuy YESX PROTEIN

(Bacillus
subtilis) 		PF01839
(FG-GAP) 		4 THR A 242
GLY A 240
ILE A 198
LEU A 246
 None
 1.04A 4acbC-2zuyA:
undetectable		 4acbC-2zuyA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zzr UNSATURATED
GLUCURONYL HYDROLASE

(Streptococcus
agalactiae) 		PF07470
(Glyco_hydro_88) 		4 GLY A 252
ILE A 174
LYS A   5
LEU A 271
 None
None
SO4  A 401 ( 4.3A)
None
 1.05A 4acbC-2zzrA:
undetectable		 4acbC-2zzrA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c2o NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Saccharomyces
cerevisiae) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 THR A 164
GLY A 141
ARG A 131
ILE A 280
 None
 0.92A 4acbC-3c2oA:
undetectable		 4acbC-3c2oA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dme CONSERVED EXPORTED
PROTEIN

(Bordetella
pertussis) 		PF01266
(DAO) 		4 THR A 354
GLY A 352
ARG A  21
ILE A 359
 FAD  A 500 (-3.8A)
FAD  A 500 (-3.1A)
None
None
 1.00A 4acbC-3dmeA:
undetectable		 4acbC-3dmeA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eh2 PROTEIN TRANSPORT
PROTEIN SEC24C

(Homo sapiens) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 GLY A 299
ARG A 219
ILE A 178
LEU A 229
 None
 1.07A 4acbC-3eh2A:
4.1		 4acbC-3eh2A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f7l COPPER,ZINC
SUPEROXIDE DISMUTASE

(Alvinella
pompejana) 		PF00080
(Sod_Cu) 		4 THR A 150
GLY A 148
ILE A 111
LEU A  20
 None
 1.00A 4acbC-3f7lA:
undetectable		 4acbC-3f7lA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ga4 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE-PROTEI
N
GLYCOSYLTRANSFERASE
SUBUNIT OST6

(Saccharomyces
cerevisiae) 		PF04756
(OST3_OST6) 		4 GLY A 144
ARG A  73
ILE A 155
LEU A 141
 None
 0.99A 4acbC-3ga4A:
undetectable		 4acbC-3ga4A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4m PROTEASOME-ACTIVATIN
G NUCLEOTIDASE

(Methanocaldococcus
jannaschii) 		PF00004
(AAA) 		4 THR A 215
GLY A 377
ILE A 349
LEU A 219
 ADP  A 439 (-4.6A)
ADP  A 439 (-3.1A)
ADP  A 439 ( 4.0A)
ADP  A 439 (-4.0A)
 1.07A 4acbC-3h4mA:
undetectable		 4acbC-3h4mA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hfw PROTEIN
ADP-RIBOSYLARGININE
HYDROLASE

(Homo sapiens) 		PF03747
(ADP_ribosyl_GH) 		4 THR A 259
GLY A 267
ARG A 234
ILE A 277
 None
 0.98A 4acbC-3hfwA:
undetectable		 4acbC-3hfwA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j7y BL17

(Homo sapiens) 		PF01196
(Ribosomal_L17) 		4 GLY O  35
ARG O 113
ILE O  42
LEU O  33
 A  A2319 ( 3.5A)
G  A2454 ( 4.6A)
A  A2319 ( 3.9A)
None
 1.01A 4acbC-3j7yO:
undetectable		 4acbC-3j7yO:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ll3 GLUCONATE KINASE

(Lactobacillus
acidophilus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 THR A 242
GLY A 244
ILE A 449
LEU A 240
 None
 0.96A 4acbC-3ll3A:
2.0		 4acbC-3ll3A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qe7 URACIL PERMEASE

(Escherichia
coli) 		PF00860
(Xan_ur_permease) 		4 THR A 220
GLY A 281
ILE A  41
LEU A 218
 None
 1.02A 4acbC-3qe7A:
undetectable		 4acbC-3qe7A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rgg PHOSPHORIBOSYLAMINOI
MIDAZOLE
CARBOXYLASE, PURE
PROTEIN

(Treponema
denticola) 		PF00731
(AIRC) 		4 THR A  27
GLY A  29
ILE A 135
LEU A  25
 None
 1.03A 4acbC-3rggA:
2.4		 4acbC-3rggA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE

(Veillonella
parvula) 		PF12706
(Lactamase_B_2) 		4 THR A   5
ARG A 234
ILE A 220
LEU A  14
 None
 0.85A 4acbC-3rpcA:
3.2		 4acbC-3rpcA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sto SERINE PROTEASE
INHIBITOR

(Schistosoma
haematobium) 		PF00079
(Serpin) 		4 THR A  49
GLY A  51
ILE A  67
LEU A  47
 None
 0.82A 4acbC-3stoA:
undetectable		 4acbC-3stoA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3syj ADHESION AND
PENETRATION PROTEIN
AUTOTRANSPORTER

(Haemophilus
influenzae) 		PF02395
(Peptidase_S6)
PF03212
(Pertactin) 		4 THR A 817
ARG A 773
ILE A 810
LEU A 836
 None
 1.07A 4acbC-3syjA:
undetectable		 4acbC-3syjA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tox SHORT CHAIN
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF13561
(adh_short_C2) 		4 GLY A 190
ARG A 223
ILE A 227
LEU A 248
 None
 1.00A 4acbC-3toxA:
6.0		 4acbC-3toxA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uwc NUCLEOTIDE-SUGAR
AMINOTRANSFERASE

(Coxiella
burnetii) 		PF01041
(DegT_DnrJ_EryC1) 		4 THR A 342
ARG A   2
ILE A 357
LEU A 287
 None
 0.93A 4acbC-3uwcA:
undetectable		 4acbC-3uwcA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpx LEUCINE
DEHYDROGENASE

(Sporosarcina
psychrophila) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 THR A 150
GLY A 153
ILE A 286
LEU A 188
 None
 1.07A 4acbC-3vpxA:
undetectable		 4acbC-3vpxA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wry TM-1 PROTEIN

(Solanum
lycopersicum) 		PF06792
(UPF0261) 		4 GLY A 264
ARG A 258
ILE A 262
LEU A 266
 None
 1.03A 4acbC-3wryA:
5.2		 4acbC-3wryA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zn6 VP17

(Thermus virus
P23-77) 		no annotation 5 THR A 173
GLY A 105
ARG A 257
ILE A 178
LEU A 108
 None
 1.45A 4acbC-3zn6A:
undetectable		 4acbC-3zn6A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b4u BIFUNCTIONAL PROTEIN
FOLD

(Acinetobacter
baumannii) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		4 THR A 141
GLY A 144
ARG A   8
ILE A 148
 None
None
EDO  A1286 (-3.5A)
None
 0.96A 4acbC-4b4uA:
undetectable		 4acbC-4b4uA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b8j IMPORTIN SUBUNIT
ALPHA-1A

(Oryza sativa) 		PF00514
(Arm)
PF01749
(IBB)
PF16186
(Arm_3) 		4 THR A 307
GLY A 309
ILE A 322
LEU A 305
 None
 1.07A 4acbC-4b8jA:
undetectable		 4acbC-4b8jA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bc6 SERINE/THREONINE-PRO
TEIN KINASE 10

(Homo sapiens) 		PF00069
(Pkinase) 		4 THR A 166
GLY A 115
ILE A 121
LEU A 164
 None
None
None
XZN  A1317 (-4.7A)
 0.65A 4acbC-4bc6A:
undetectable		 4acbC-4bc6A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cr4 26S PROTEASE SUBUNIT
RPT4

(Saccharomyces
cerevisiae) 		PF00004
(AAA) 		4 THR L 226
GLY L 388
ILE L 360
LEU L 230
 None
 0.88A 4acbC-4cr4L:
undetectable		 4acbC-4cr4L:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f92 U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 THR B 561
GLY B 563
ILE B 531
LEU B 559
 None
 1.05A 4acbC-4f92B:
undetectable		 4acbC-4f92B:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h3v OXIDOREDUCTASE
DOMAIN PROTEIN

(Kribbella
flavida) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 THR A 155
GLY A 281
ARG A 145
ILE A 279
 None
 0.89A 4acbC-4h3vA:
undetectable		 4acbC-4h3vA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i7a ETHANOLAMINE
UTILIZATION PROTEIN
EUTN/CARBOXYSOME
STRUCTURAL PROTEIN
CCML

(Rhodospirillum
rubrum) 		PF03319
(EutN_CcmL) 		4 THR A  46
GLY A  48
ILE A  81
LEU A  25
 None
 1.06A 4acbC-4i7aA:
undetectable		 4acbC-4i7aA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdy PYRIDOXAL
BIOSYNTHESIS LYASE
PDXS

(Mycobacterium
tuberculosis) 		PF01680
(SOR_SNZ) 		4 THR A 100
GLY A 102
ILE A  76
LEU A  98
 None
 1.06A 4acbC-4jdyA:
undetectable		 4acbC-4jdyA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jvz CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN

(Thermosynechococcus
elongatus) 		PF03319
(EutN_CcmL) 		4 THR A  46
GLY A  48
ILE A  81
LEU A  25
 None
 1.06A 4acbC-4jvzA:
undetectable		 4acbC-4jvzA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k35 GLYCOSIDE HYDROLASE
FAMILY 81
ENDO-BETA-1,3-GLUCAN
ASE

(Rhizomucor
miehei) 		PF03639
(Glyco_hydro_81) 		4 THR A 242
ARG A 201
ILE A 245
LEU A 171
 None
 1.02A 4acbC-4k35A:
undetectable		 4acbC-4k35A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ks8 SERINE/THREONINE-PRO
TEIN KINASE PAK 6

(Homo sapiens) 		PF00069
(Pkinase) 		4 THR A 535
GLY A 486
ILE A 492
LEU A 533
 None
None
None
B49  A 701 (-4.5A)
 0.95A 4acbC-4ks8A:
undetectable		 4acbC-4ks8A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kvf RHAMNOSE ABC
TRANSPORTER,
PERIPLASMIC
RHAMNOSE-BINDING
PROTEIN

(Kribbella
flavida) 		PF13407
(Peripla_BP_4) 		4 THR A 254
GLY A 278
ARG A 263
ILE A 276
 GOL  A 402 (-4.6A)
None
None
None
 1.06A 4acbC-4kvfA:
undetectable		 4acbC-4kvfA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l0c DEFORMYLASE

(Pseudomonas
putida) 		PF12697
(Abhydrolase_6) 		4 THR A 188
GLY A 123
ARG A 105
ILE A 191
 None
 1.01A 4acbC-4l0cA:
undetectable		 4acbC-4l0cA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ohs FAR-RED FLUORESCENT
PROTEIN AQ143

(Actinia equina) 		PF01353
(GFP) 		4 THR A  14
GLY A  28
ILE A  43
LYS A  66
 None
None
None
CH6  A  63 ( 3.6A)
 1.07A 4acbC-4ohsA:
undetectable		 4acbC-4ohsA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pmz XYLANASE

(Xanthomonas
citri) 		PF00331
(Glyco_hydro_10) 		4 GLY A 219
ARG A 177
ILE A 187
LEU A 243
 None
 0.97A 4acbC-4pmzA:
2.5		 4acbC-4pmzA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r1d UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		no annotation 4 GLY A 346
ARG A 441
ILE A 444
LEU A 349
 None
 1.01A 4acbC-4r1dA:
2.7		 4acbC-4r1dA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8j PESTICIDAL CRYSTAL
PROTEIN CRY1AC

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 THR A 705
GLY A 703
ILE A 693
LEU A 723
 None
 1.05A 4acbC-4w8jA:
undetectable		 4acbC-4w8jA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wli YUIC

(Bacillus
subtilis) 		PF06725
(3D) 		4 THR A 125
GLY A 147
ARG A 160
ILE A 141
 None
 0.84A 4acbC-4wliA:
undetectable		 4acbC-4wliA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4woj ASPARTATE
SEMIALDEHYDE
DEHYDROGENASE

(Francisella
tularensis) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 THR A  33
GLY A   5
ARG A  10
ILE A   7
 None
None
SO4  A 402 (-3.1A)
None
 0.75A 4acbC-4wojA:
2.4		 4acbC-4wojA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzi SENSORY OPSIN
A,ARCHAEAL-TYPE
OPSIN 2

(Chlamydomonas
reinhardtii) 		PF01036
(Bac_rhodopsin) 		4 THR A 285
GLY A 287
ILE A 291
LEU A  94
 None
OLA  A 406 (-3.5A)
None
None
 0.83A 4acbC-4yziA:
undetectable		 4acbC-4yziA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c3m PUTATIVE
6-PHOSPHO-BETA-GLUCO
SIDASE

(Geobacillus
stearothermophilus) 		PF02056
(Glyco_hydro_4)
PF11975
(Glyco_hydro_4C) 		4 THR A 113
GLY A 115
ARG A 259
ILE A 109
 None
 1.06A 4acbC-5c3mA:
4.1		 4acbC-5c3mA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cwv NUCLEOPORIN NUP192

(Chaetomium
thermophilum) 		PF11894
(Nup192) 		4 THR A1731
GLY A1734
ILE A1658
LEU A1729
 None
 1.01A 4acbC-5cwvA:
undetectable		 4acbC-5cwvA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ezr CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE

(Plasmodium
vivax) 		PF00027
(cNMP_binding)
PF00069
(Pkinase) 		4 THR A 280
ARG A 348
ILE A 328
LEU A 300
 None
 0.87A 4acbC-5ezrA:
undetectable		 4acbC-5ezrA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5o NUCLEOPROTEIN

(Marburg
marburgvirus) 		PF05505
(Ebola_NP) 		4 GLY A  54
ARG A  82
ILE A 191
LEU A  59
 None
 0.83A 4acbC-5f5oA:
undetectable		 4acbC-5f5oA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fn3 PRESENILIN-1

(Homo sapiens) 		PF01080
(Presenilin) 		4 THR B 440
GLY B 442
ILE B 414
LEU B 250
 None
 0.91A 4acbC-5fn3B:
undetectable		 4acbC-5fn3B:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5g PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT

(Escherichia
coli;
Escherichia
coli) 		PF00111
(Fer2)
PF01799
(Fer2_2)
PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C) 		4 GLY B  30
ARG B   8
ILE B  28
LEU A 120
 FAD  B 321 (-3.2A)
None
None
None
 0.97A 4acbC-5g5gB:
undetectable		 4acbC-5g5gB:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggy IRON(III) ABC
TRANSPORTER,
PERIPLASMIC
IRON-COMPOUND-BINDIN
G PROTEIN

(Vibrio cholerae) 		PF01497
(Peripla_BP_2) 		4 THR A 130
GLY A 132
ILE A 118
LEU A 128
 None
 1.03A 4acbC-5ggyA:
undetectable		 4acbC-5ggyA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsm EXO-BETA-D-GLUCOSAMI
NIDASE

(Thermococcus
kodakarensis) 		PF02449
(Glyco_hydro_42) 		4 THR A  24
GLY A  23
ARG A 411
ILE A 417
 None
 1.06A 4acbC-5gsmA:
undetectable		 4acbC-5gsmA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7w VENOM
5'-NUCLEOTIDASE

(Naja atra) 		no annotation 4 THR A 177
GLY A 219
ARG A 228
LEU A 140
 None
 1.03A 4acbC-5h7wA:
2.5		 4acbC-5h7wA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i3a TYROSINASE

(Bacillus
megaterium) 		PF00264
(Tyrosinase) 		4 THR A 137
GLY A 147
ARG A 151
ILE A 125
 None
 0.95A 4acbC-5i3aA:
undetectable		 4acbC-5i3aA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i3e PUTATIVE
DEOXYRIBONUCLEASE-2

(Burkholderia
thailandensis) 		PF03265
(DNase_II) 		4 THR A 150
GLY A 152
ILE A 105
LEU A 148
 None
 1.04A 4acbC-5i3eA:
undetectable		 4acbC-5i3eA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i93 1,2-DIHYDROXY-3-KETO
-5-METHYLTHIOPENTENE
DIOXYGENASE

(Mus musculus) 		PF03079
(ARD) 		4 THR A  33
GLY A  35
ILE A 131
LEU A  31
 None
 1.07A 4acbC-5i93A:
undetectable		 4acbC-5i93A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR

(Burkholderia
vietnamiensis) 		PF00106
(adh_short) 		4 THR A 102
GLY A 106
ILE A  59
LEU A  76
 None
 0.97A 4acbC-5idqA:
3.4		 4acbC-5idqA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j44 SERINE PROTEASE SEPA
AUTOTRANSPORTER

(Shigella
flexneri) 		PF02395
(Peptidase_S6) 		4 THR A  56
GLY A  63
ARG A  13
LEU A  60
 None
 0.93A 4acbC-5j44A:
undetectable		 4acbC-5j44A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3s SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN

(Sulfolobus
solfataricus) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 THR A 111
GLY A 114
ILE A 150
LEU A 279
 GNP  A 301 (-3.7A)
None
None
None
 1.02A 4acbC-5l3sA:
7.1		 4acbC-5l3sA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg5 HYDROXYMETHYLGLUTARY
L-COA SYNTHASE

(Pseudomonas
protegens) 		no annotation 4 THR A  57
GLY A  59
ARG A  90
ILE A  96
 None
 1.02A 4acbC-5mg5A:
undetectable		 4acbC-5mg5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqs BETA-L-ARABINOBIOSID
ASE

(Bacteroides
thetaiotaomicron) 		PF13088
(BNR_2) 		4 THR A 294
GLY A 292
ARG A  28
ILE A 276
 None
 1.02A 4acbC-5mqsA:
undetectable		 4acbC-5mqsA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tg8 HEMAGGLUTININ HA1
CHAIN

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 THR A 287
GLY A  47
ARG A 300
ILE A 297
 None
 1.07A 4acbC-5tg8A:
undetectable		 4acbC-5tg8A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tv7 PUTATIVE
PEPTIDOGLYCAN-BINDIN
G/HYDROLYSING
PROTEIN

(Clostridioides
difficile) 		PF01471
(PG_binding_1) 		4 THR A 127
GLY A 184
ILE A 131
LEU A 191
 None
HGA  A 301 (-3.3A)
None
None
 1.04A 4acbC-5tv7A:
undetectable		 4acbC-5tv7A:
17.23