SIMILAR PATTERNS OF AMINO ACIDS FOR 4ACB_C_DXCC1475_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cli PROTEIN
(PHOSPHORIBOSYL-AMIN
OIMIDAZOLE
SYNTHETASE)

(Escherichia
coli) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 ILE A 123
ILE A 126
PHE A 105
GLY A 158
 None
 0.77A 4acbC-1cliA:
undetectable		 4acbC-1cliA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d8c MALATE SYNTHASE G

(Escherichia
coli) 		PF01274
(Malate_synthase) 		4 ILE A 109
ASP A 106
ILE A 105
VAL A 100
 None
 0.76A 4acbC-1d8cA:
2.5		 4acbC-1d8cA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE

(Escherichia
virus T4) 		no annotation 4 ILE A 143
ASP A 148
ILE A  96
GLY A  92
 None
 0.76A 4acbC-1delA:
2.2		 4acbC-1delA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl2 CLASS I
ALPHA-1,2-MANNOSIDAS
E

(Saccharomyces
cerevisiae) 		PF01532
(Glyco_hydro_47) 		4 ILE A  83
ASP A  86
PHE A 499
GLN A 432
 None
None
GOL  A 900 (-3.3A)
None
 0.77A 4acbC-1dl2A:
undetectable		 4acbC-1dl2A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Escherichia
coli) 		PF02350
(Epimerase_2) 		4 ILE A 166
PHE A 146
SER A 103
GLY A 114
 None
 0.76A 4acbC-1f6dA:
3.6		 4acbC-1f6dA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i8q HYALURONATE LYASE

(Streptococcus
agalactiae) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 ILE A 880
ASP A 850
ILE A 851
PHE A 822
 None
 0.77A 4acbC-1i8qA:
undetectable		 4acbC-1i8qA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iub FUCOSE-SPECIFIC
LECTIN

(Aleuria
aurantia) 		PF07938
(Fungal_lectin) 		4 ILE A 276
ASP A 275
ILE A 274
GLY A 220
 None
 0.76A 4acbC-1iubA:
undetectable		 4acbC-1iubA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7y METHIONINE SYNTHASE

(Escherichia
coli) 		PF02310
(B12-binding)
PF02607
(B12-binding_2)
PF02965
(Met_synt_B12) 		4 ILE A 846
ILE A 832
VAL A 754
GLY A 805
 None
 0.71A 4acbC-1k7yA:
2.7		 4acbC-1k7yA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lj9 TRANSCRIPTIONAL
REGULATOR SLYA

(Enterococcus
faecalis) 		PF01047
(MarR) 		4 ILE A  50
ILE A  54
GLN A  32
GLY A  31
 None
 0.75A 4acbC-1lj9A:
undetectable		 4acbC-1lj9A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mwo ALPHA AMYLASE

(Pyrococcus
woesei) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		5 ILE A 165
ASP A 145
PHE A 131
SER A  55
GLY A 114
 None
 1.12A 4acbC-1mwoA:
2.3		 4acbC-1mwoA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pqs CELL DIVISION
CONTROL PROTEIN 24

(Saccharomyces
cerevisiae) 		PF00564
(PB1) 		4 ILE A 798
ILE A 795
PHE A 791
GLY A 829
 None
 0.75A 4acbC-1pqsA:
undetectable		 4acbC-1pqsA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pzv PROBABLE
UBIQUITIN-CONJUGATIN
G ENZYME E2-19 KDA

(Caenorhabditis
elegans) 		PF00179
(UQ_con) 		4 ILE A  81
ILE A  76
VAL A  40
GLY A  42
 None
 0.64A 4acbC-1pzvA:
undetectable		 4acbC-1pzvA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1o CELL DIVISION
CONTROL PROTEIN 24

(Saccharomyces
cerevisiae) 		PF00564
(PB1) 		4 ILE A 798
ILE A 795
PHE A 791
GLY A 829
 None
 0.79A 4acbC-1q1oA:
undetectable		 4acbC-1q1oA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qcq PROTEIN (UBIQUITIN
CONJUGATING ENZYME)

(Saccharomyces
cerevisiae) 		PF00179
(UQ_con) 		4 ILE A  79
ILE A  74
SER A  21
GLY A  40
 None
 0.79A 4acbC-1qcqA:
undetectable		 4acbC-1qcqA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9f PROTEIN 1D10

(Caenorhabditis
elegans) 		PF02815
(MIR) 		4 ILE A  94
ASP A  92
ILE A  88
GLY A  85
 None
 0.76A 4acbC-1t9fA:
undetectable		 4acbC-1t9fA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9p DNA LIGASE

(Thermus
filiformis) 		PF01653
(DNA_ligase_aden)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 ILE A 155
ILE A 158
VAL A 124
GLY A 136
 None
 0.71A 4acbC-1v9pA:
undetectable		 4acbC-1v9pA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023

(Staphylococcus
aureus) 		PF02590
(SPOUT_MTase) 		4 ILE A  33
ILE A   3
PHE A 105
SER A  85
 None
 0.80A 4acbC-1vh0A:
undetectable		 4acbC-1vh0A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz2 LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 ILE A 849
ASP A 845
ILE A 964
GLN A 956
 A  C 953 ( 4.0A)
G  C 954 ( 3.3A)
G  C 954 ( 4.5A)
None
 0.79A 4acbC-1wz2A:
undetectable		 4acbC-1wz2A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x4b HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEINS
A2/B1

(Homo sapiens) 		PF00076
(RRM_1) 		4 ILE A  93
ASP A  94
VAL A  74
GLY A  72
 None
 0.81A 4acbC-1x4bA:
undetectable		 4acbC-1x4bA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xvt CROTONOBETAINYL-COA:
CARNITINE
COA-TRANSFERASE

(Escherichia
coli) 		PF02515
(CoA_transf_3) 		4 ILE A 196
ASP A 197
ILE A 198
GLY A  26
 None
 0.62A 4acbC-1xvtA:
3.5		 4acbC-1xvtA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yns E-1 ENZYME

(Homo sapiens) 		no annotation 4 ASP A 171
ILE A 172
PHE A 164
VAL A 135
 None
 0.80A 4acbC-1ynsA:
3.4		 4acbC-1ynsA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cu0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF00478
(IMPDH)
PF00571
(CBS) 		4 ILE A  40
ASP A 352
ILE A 332
GLY A 274
 None
 0.72A 4acbC-2cu0A:
undetectable		 4acbC-2cu0A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF) 		4 ILE A1075
ILE A1087
VAL A1135
GLY A1080
 None
 0.72A 4acbC-2eyqA:
undetectable		 4acbC-2eyqA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f4n HYPOTHETICAL PROTEIN
MJ1651

(Methanocaldococcus
jannaschii) 		PF01887
(SAM_adeno_trans) 		4 ILE A 203
ILE A 215
PHE A 230
VAL A 255
 None
 0.74A 4acbC-2f4nA:
3.0		 4acbC-2f4nA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h18 ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
8A

(Homo sapiens) 		PF00025
(Arf) 		4 ILE A 170
ASP A 168
ILE A 162
VAL A  93
 None
 0.74A 4acbC-2h18A:
12.2		 4acbC-2h18A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hj1 HYPOTHETICAL PROTEIN

(Haemophilus
influenzae) 		PF03658
(Ub-RnfH) 		4 ILE A  13
ILE A  15
PHE A  30
GLN A  44
 None
 0.49A 4acbC-2hj1A:
undetectable		 4acbC-2hj1A:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i34 ACID PHOSPHATASE

(Bacillus
anthracis) 		PF03767
(Acid_phosphat_B) 		4 ILE A 120
ILE A  62
PHE A 178
GLY A  44
 None
 0.72A 4acbC-2i34A:
2.9		 4acbC-2i34A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jep XYLOGLUCANASE

(Paenibacillus
pabuli) 		PF00150
(Cellulase) 		4 ILE A 176
ILE A 127
VAL A 357
GLY A  45
 None
 0.77A 4acbC-2jepA:
3.5		 4acbC-2jepA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2klx GLUTAREDOXIN

(Bartonella
henselae) 		PF00462
(Glutaredoxin) 		4 ILE A   4
ASP A  83
GLN A  54
GLY A  63
 None
 0.72A 4acbC-2klxA:
undetectable		 4acbC-2klxA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m4l PROTEIN BT_0846

(Bacteroides
thetaiotaomicron) 		no annotation 5 ILE A  55
ILE A  12
PHE A  29
VAL A  86
SER A  90
 None
 1.20A 4acbC-2m4lA:
undetectable		 4acbC-2m4lA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oua SERINE PROTEASE

(Nocardiopsis
alba) 		PF00089
(Trypsin) 		4 ASP A  15
ILE A  16
VAL A 106
GLY A 108
 None
 0.61A 4acbC-2ouaA:
2.7		 4acbC-2ouaA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pal PARVALBUMIN

(Esox lucius) 		PF13499
(EF-hand_7) 		4 ILE A  50
ASP A  51
ILE A  58
GLY A  89
 None
MN  A 111 ( 2.9A)
None
None
 0.78A 4acbC-2palA:
undetectable		 4acbC-2palA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE

(Escherichia
virus N4) 		no annotation 4 ILE A  12
ASP A  13
GLN A 150
GLY A  50
 None
 0.69A 4acbC-2po4A:
undetectable		 4acbC-2po4A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qvw GLP_546_48378_50642

(Giardia
intestinalis) 		PF00636
(Ribonuclease_3)
PF02170
(PAZ) 		4 ILE A 529
ASP A 528
SER A 541
GLY A 536
 None
 0.83A 4acbC-2qvwA:
undetectable		 4acbC-2qvwA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qx2 SEX PHEROMONE
STAPH-CAM373

(Staphylococcus
aureus) 		PF07537
(CamS) 		4 ILE A 373
ILE A 340
GLN A 345
GLY A 344
 None
None
None
EDO  A 402 ( 3.7A)
 0.83A 4acbC-2qx2A:
undetectable		 4acbC-2qx2A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qyg RIBULOSE
BISPHOSPHATE
CARBOXYLASE-LIKE
PROTEIN 2

(Rhodopseudomonas
palustris) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 ILE A 234
ILE A 196
VAL A 318
GLY A 378
 None
 0.83A 4acbC-2qygA:
undetectable		 4acbC-2qygA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qyv XAA-HIS DIPEPTIDASE

(Histophilus
somni) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ILE A 219
ASP A 218
SER A 361
GLY A 350
 None
 0.80A 4acbC-2qyvA:
2.5		 4acbC-2qyvA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xe4 OLIGOPEPTIDASE B

(Leishmania
major) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		4 ILE A 687
ILE A 654
SER A 641
GLY A 584
 None
 0.81A 4acbC-2xe4A:
3.8		 4acbC-2xe4A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yfq NAD-SPECIFIC
GLUTAMATE
DEHYDROGENASE

(Peptoniphilus
asaccharolyticus) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ILE A 408
ASP A 412
ILE A 411
SER A  60
 None
 0.78A 4acbC-2yfqA:
undetectable		 4acbC-2yfqA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zsg AMINOPEPTIDASE P,
PUTATIVE

(Thermotoga
maritima) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		4 ASP A 271
ILE A 305
VAL A 317
GLY A 302
 None
 0.75A 4acbC-2zsgA:
undetectable		 4acbC-2zsgA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Bacillus
anthracis) 		PF02350
(Epimerase_2) 		4 ILE A 171
PHE A 151
SER A 108
GLY A 119
 None
 0.79A 4acbC-3beoA:
7.7		 4acbC-3beoA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwk PENICILLIN-BINDING
PROTEIN 2

(Staphylococcus
aureus) 		PF00905
(Transpeptidase)
PF00912
(Transgly) 		4 ILE A 490
ASP A 489
VAL A 466
GLY A 471
 None
 0.75A 4acbC-3dwkA:
undetectable		 4acbC-3dwkA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0g LEUKEMIA INHIBITORY
FACTOR RECEPTOR

(Homo sapiens) 		PF00041
(fn3) 		4 ILE A 216
ASP A 215
ILE A 253
GLY A 279
 None
 0.81A 4acbC-3e0gA:
undetectable		 4acbC-3e0gA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gay FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Giardia
intestinalis) 		PF01116
(F_bP_aldolase) 		4 ILE A 238
ILE A 241
VAL A 254
GLY A  21
 None
None
P6T  A 327 (-4.3A)
None
 0.72A 4acbC-3gayA:
2.8		 4acbC-3gayA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gsi N,N-DIMETHYLGLYCINE
OXIDASE

(Arthrobacter
globiformis) 		PF01266
(DAO)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF16350
(FAO_M) 		4 ILE A 804
ASP A 803
ILE A 811
GLY A 754
 None
 0.70A 4acbC-3gsiA:
4.2		 4acbC-3gsiA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h8w RIBONUCLEASE H

(Escherichia
virus T4) 		PF02739
(5_3_exonuc_N)
PF09293
(RNaseH_C) 		4 ILE A 152
ASP A  19
ILE A  23
PHE A  20
 None
 0.80A 4acbC-3h8wA:
undetectable		 4acbC-3h8wA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jtg ETS-RELATED
TRANSCRIPTION FACTOR
ELF-3

(Mus musculus) 		PF00178
(Ets) 		4 ILE A 282
ASP A 281
GLN A 317
GLY A 316
 None
 0.75A 4acbC-3jtgA:
undetectable		 4acbC-3jtgA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lm6 STAGE V SPORULATION
PROTEIN AD

(Bacillus
subtilis) 		PF07451
(SpoVAD) 		4 ILE A 213
PHE A 303
SER A 113
GLY A 328
 None
 0.80A 4acbC-3lm6A:
undetectable		 4acbC-3lm6A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n2c PROLIDASE

(unidentified) 		PF01979
(Amidohydro_1) 		4 ILE A 187
ILE A 215
VAL A 166
GLY A 171
 KCX  A 188 ( 3.6A)
None
None
None
 0.77A 4acbC-3n2cA:
3.2		 4acbC-3n2cA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nv9 MALIC ENZYME

(Entamoeba
histolytica) 		PF00390
(malic)
PF03949
(Malic_M) 		4 ILE A 322
PHE A 324
SER A 387
GLY A 205
 None
 0.78A 4acbC-3nv9A:
undetectable		 4acbC-3nv9A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p4e PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE

(Vibrio cholerae) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 ILE A 124
ILE A 127
PHE A 106
GLY A 159
 AMP  A 501 (-4.4A)
None
None
None
 0.80A 4acbC-3p4eA:
undetectable		 4acbC-3p4eA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qbo PHOSPHOSERINE
AMINOTRANSFERASE

(Yersinia pestis) 		PF00266
(Aminotran_5) 		4 ASP A 160
ILE A 159
VAL A  97
GLY A  99
 None
 0.79A 4acbC-3qboA:
undetectable		 4acbC-3qboA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 ILE A 237
ASP A 238
PHE A 251
VAL A 191
 None
 0.82A 4acbC-3szeA:
2.4		 4acbC-3szeA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 ILE A 717
PHE A 704
VAL A 729
GLY A 707
 None
 0.82A 4acbC-3szeA:
2.4		 4acbC-3szeA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t2n SERINE PROTEASE
HEPSIN

(Homo sapiens) 		PF00089
(Trypsin)
PF09272
(Hepsin-SRCR) 		4 ILE A 258
ASP A 257
ILE A 374
GLY A 190
 None
 0.77A 4acbC-3t2nA:
undetectable		 4acbC-3t2nA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tx1 UDP-N-ACETYLENOLPYRU
VOYLGLUCOSAMINE
REDUCTASE

(Listeria
monocytogenes) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		4 ILE A  73
ILE A  68
SER A 125
GLY A  63
 None
None
FAD  A 299 (-2.8A)
FAD  A 299 (-3.0A)
 0.67A 4acbC-3tx1A:
undetectable		 4acbC-3tx1A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uto TWITCHIN

(Caenorhabditis
elegans) 		PF00041
(fn3)
PF00069
(Pkinase)
PF07679
(I-set) 		4 ILE A 296
ASP A 297
ILE A 452
GLY A 163
 None
 0.80A 4acbC-3utoA:
undetectable		 4acbC-3utoA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uv1 DER F 7 ALLERGEN

(Dermatophagoides
farinae) 		PF16984
(Grp7_allergen) 		4 ILE A  29
ASP A  30
VAL A 123
GLY A  89
 None
 0.83A 4acbC-3uv1A:
undetectable		 4acbC-3uv1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vly NITRITE REDUCTASE

(Nicotiana
tabacum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 ILE A 396
ILE A 404
VAL A 376
GLY A 374
 None
None
None
K  A 603 ( 4.6A)
 0.81A 4acbC-3vlyA:
undetectable		 4acbC-3vlyA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vyl L-RIBULOSE
3-EPIMERASE

(Mesorhizobium
loti) 		PF01261
(AP_endonuc_2) 		5 ILE A 220
ASP A 221
ILE A 225
PHE A 226
VAL A 205
 None
 1.43A 4acbC-3vylA:
2.2		 4acbC-3vylA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ypi TRIOSEPHOSPHATE
ISOMERASE

(Saccharomyces
cerevisiae) 		PF00121
(TIM) 		4 ASP A 242
ILE A 243
PHE A 240
GLY A   9
 None
 0.69A 4acbC-3ypiA:
3.2		 4acbC-3ypiA:
20.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4aca TRANSLATION
ELONGATION FACTOR
SELB

(Methanococcus
maripaludis) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		4 PHE A  51
SER A 231
GLN A 233
GLY A 249
 None
 0.50A 4acbC-4acaA:
51.7		 4acbC-4acaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4aca TRANSLATION
ELONGATION FACTOR
SELB

(Methanococcus
maripaludis) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		4 PHE A  51
VAL A 202
GLN A 233
GLY A 249
 None
 0.53A 4acbC-4acaA:
51.7		 4acbC-4acaA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmb GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 ILE A  35
ILE A 149
PHE A  19
GLY A  21
 None
 0.79A 4acbC-4bmbA:
undetectable		 4acbC-4bmbA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bz4 COPPER-REPRESSIBLE
POLYPEPTIDE

(Methylomicrobium
album) 		no annotation 4 ILE A 122
ASP A 121
VAL A 195
GLN A 118
 None
 0.81A 4acbC-4bz4A:
undetectable		 4acbC-4bz4A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dk1 PUTATIVE MACA,
MULTIDRUG RESISTANCE
PROTEIN MEXA

(Pseudomonas
aeruginosa;
Aggregatibacter
actinomycetemcomitans) 		PF16576
(HlyD_D23) 		4 ILE A 227
ASP A 228
ILE A 249
GLY A  50
 None
 0.75A 4acbC-4dk1A:
3.9		 4acbC-4dk1A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0a PROTEIN WNT-8

(Xenopus laevis) 		PF00110
(wnt) 		4 ASP B 204
ILE B 205
PHE B 202
GLY B  96
 None
 0.81A 4acbC-4f0aB:
undetectable		 4acbC-4f0aB:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ga6 PUTATIVE THYMIDINE
PHOSPHORYLASE

(Thermococcus
kodakarensis) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C) 		4 ILE A 428
ASP A 429
ILE A 433
GLY A 171
 None
 0.71A 4acbC-4ga6A:
3.2		 4acbC-4ga6A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfh DNA TOPOISOMERASE 2

(Saccharomyces
cerevisiae) 		PF00204
(DNA_gyraseB)
PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF02518
(HATPase_c)
PF16898
(TOPRIM_C) 		4 ASP A 639
ILE A 638
PHE A 642
GLY A 536
 None
 0.77A 4acbC-4gfhA:
undetectable		 4acbC-4gfhA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM)
PF07496
(zf-CW) 		4 ILE A 781
ASP A 780
GLN A 503
GLY A 774
 None
 0.75A 4acbC-4hsuA:
undetectable		 4acbC-4hsuA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kjz TRANSLATION
INITIATION FACTOR
IF-2

(Thermus
thermophilus) 		PF00009
(GTP_EFTU)
PF04760
(IF2_N)
PF11987
(IF-2) 		4 ASP A 238
VAL A 122
GLN A 119
GLY A 120
 None
 0.74A 4acbC-4kjzA:
18.4		 4acbC-4kjzA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA

(Planctopirus
limnophila) 		PF00575
(S1)
PF08529
(NusA_N)
PF13184
(KH_5)
PF14520
(HHH_5) 		4 ASP A  73
VAL A   6
SER A  54
GLY A   3
 None
 0.82A 4acbC-4mtnA:
undetectable		 4acbC-4mtnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA

(Planctopirus
limnophila) 		PF00575
(S1)
PF08529
(NusA_N)
PF13184
(KH_5)
PF14520
(HHH_5) 		4 ILE A  74
ASP A  73
SER A  54
GLY A   3
 None
 0.79A 4acbC-4mtnA:
undetectable		 4acbC-4mtnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9x PUTATIVE
MONOOXYGENASE

(Pectobacterium
atrosepticum) 		PF01494
(FAD_binding_3) 		4 ASP A 126
ILE A  29
VAL A 161
GLY A  15
 None
 0.82A 4acbC-4n9xA:
undetectable		 4acbC-4n9xA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ncn EUKARYOTIC
TRANSLATION
INITIATION FACTOR
5B-LIKE PROTEIN

(Chaetomium
thermophilum) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		4 ILE A 592
ASP A 594
ILE A 528
VAL A 644
 None
MG  A1002 ( 4.1A)
None
None
 0.76A 4acbC-4ncnA:
19.2		 4acbC-4ncnA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pq0 FACT COMPLEX SUBUNIT
POB3

(Saccharomyces
cerevisiae) 		PF08512
(Rtt106) 		4 ILE A 266
ASP A 260
ILE A 261
PHE A 245
 None
 0.70A 4acbC-4pq0A:
undetectable		 4acbC-4pq0A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbj BLR1131 PROTEIN

(Bradyrhizobium
diazoefficiens) 		PF02630
(SCO1-SenC) 		4 ILE A 102
ILE A  67
VAL A 140
GLY A  42
 None
 0.71A 4acbC-4wbjA:
2.5		 4acbC-4wbjA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x7m TARM

(Staphylococcus
aureus) 		PF00534
(Glycos_transf_1) 		4 ILE A 414
PHE A 431
GLN A 405
GLY A 406
 None
None
None
UDP  A 500 ( 3.8A)
 0.83A 4acbC-4x7mA:
6.9		 4acbC-4x7mA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zhj MG-CHELATASE SUBUNIT
CHLH

(Synechocystis
sp. PCC 6803) 		PF02514
(CobN-Mg_chel)
PF11965
(DUF3479) 		4 ILE A 928
ILE A 785
VAL A 901
SER A 774
 None
 0.81A 4acbC-4zhjA:
4.5		 4acbC-4zhjA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a2o NITRATE TRANSPORTER
1.1

(Arabidopsis
thaliana) 		PF00854
(PTR2) 		4 ILE A 197
PHE A 190
VAL A 167
GLY A 171
 None
 0.81A 4acbC-5a2oA:
undetectable		 4acbC-5a2oA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a4m HYDROGENASE-1 SMALL
CHAIN

(Escherichia
coli) 		PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C) 		5 ILE S 138
ASP S 135
ILE S 134
SER S  90
GLY S  14
 None
 1.46A 4acbC-5a4mS:
5.1		 4acbC-5a4mS:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE

(Sulfolobus
acidocaldarius) 		no annotation 4 ILE A 157
ASP A 159
VAL A 131
GLY A  95
 None
 0.72A 4acbC-5a7tA:
undetectable		 4acbC-5a7tA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		PF12625
(Arabinose_bd)
PF12833
(HTH_18) 		4 ILE A 105
ASP A 118
ILE A 119
PHE A 189
 None
 0.75A 4acbC-5chhA:
undetectable		 4acbC-5chhA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eod COAGULATION FACTOR
XI

(Homo sapiens) 		PF00024
(PAN_1)
PF00089
(Trypsin) 		4 ILE A 463
ASP A 462
ILE A 574
GLY A 400
 None
 0.79A 4acbC-5eodA:
2.2		 4acbC-5eodA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epo 7-ALPHA-HYDROXYSTERO
ID DEYDROGENASE

(Clostridium
sardiniense) 		PF13561
(adh_short_C2) 		4 ILE A  50
ASP A  49
VAL A  11
GLY A  19
 None
 0.73A 4acbC-5epoA:
4.4		 4acbC-5epoA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fei DISTAL TUBE PROTEIN

(Bacillus virus
phi29) 		PF16838
(Caud_tail_N) 		4 ILE A  13
ILE A  78
PHE A 109
VAL A  51
 None
 0.77A 4acbC-5feiA:
2.7		 4acbC-5feiA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzg GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 ILE A  35
ILE A 149
PHE A  19
GLY A  21
 None
 0.77A 4acbC-5gzgA:
undetectable		 4acbC-5gzgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hc4 LIPOLYTIC ENZYME

(uncultured
bacterium) 		PF07859
(Abhydrolase_3) 		4 ILE A  11
ILE A  15
PHE A  19
SER A 188
 None
None
None
TRS  A 402 (-2.3A)
 0.82A 4acbC-5hc4A:
3.7		 4acbC-5hc4A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ido 3' TERMINAL URIDYLYL
TRANSFERASE

(Trypanosoma
brucei) 		PF03828
(PAP_assoc) 		4 ILE A 295
ASP A 312
ILE A 311
GLY A 307
 None
UTP  A 701 ( 4.7A)
None
None
 0.60A 4acbC-5idoA:
undetectable		 4acbC-5idoA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kh0 SMALL GTP-BINDING
PROTEIN

(Thermosipho
melanesiensis) 		PF01926
(MMR_HSR1) 		4 ILE A 294
ILE A 347
SER A 243
GLY A 377
 None
 0.81A 4acbC-5kh0A:
15.8		 4acbC-5kh0A:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN

(Escherichia
coli) 		PF00258
(Flavodoxin_1)
PF00301
(Rubredoxin)
PF00753
(Lactamase_B) 		4 ILE A  72
ASP A  71
ILE A  67
VAL A  12
 None
 0.80A 4acbC-5lmcA:
4.4		 4acbC-5lmcA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m42 PROLINE
DEHYDROGENASE

(Thermus
thermophilus) 		PF01619
(Pro_dh) 		4 ILE A  59
PHE A 129
VAL A 161
GLY A 159
 None
None
FMN  A2001 (-4.3A)
None
 0.76A 4acbC-5m42A:
2.9		 4acbC-5m42A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uak CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR

(Homo sapiens) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane)
PF14396
(CFTR_R) 		4 ILE A 991
ILE A 995
VAL A 862
GLY A 934
 None
 0.77A 4acbC-5uakA:
undetectable		 4acbC-5uakA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vk4 PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE

(Neisseria
gonorrhoeae) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 ILE A 121
ILE A 124
PHE A 103
GLY A 156
 ANP  A 401 (-4.5A)
None
None
None
 0.83A 4acbC-5vk4A:
undetectable		 4acbC-5vk4A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgt SINGLE-STRANDED
DNA-BINDING PROTEIN

(Staphylococcus
aureus) 		PF00436
(SSB) 		4 VAL A   6
SER A  99
GLN A 101
GLY A  72
 None
 0.65A 4acbC-5xgtA:
undetectable		 4acbC-5xgtA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yly NITRATE REDUCTASE

(Ulva prolifera) 		no annotation 4 ILE A 765
ILE A 755
SER A 731
GLY A 722
 None
 0.81A 4acbC-5ylyA:
3.3		 4acbC-5ylyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zct -

(-) 		no annotation 4 ILE A 276
ASP A 277
ILE A 278
GLY A 266
 None
 0.80A 4acbC-5zctA:
4.6		 4acbC-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d0p PIRIN FAMILY PROTEIN

(Acinetobacter
baumannii) 		no annotation 4 ILE A 148
ASP A 147
ILE A 143
VAL A  69
 None
 0.79A 4acbC-6d0pA:
undetectable		 4acbC-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN

(Homo sapiens) 		no annotation 4 ILE A 397
ILE A 424
SER A 352
GLY A 359
 None
None
None
AYE  A 601 ( 4.7A)
 0.83A 4acbC-6ei1A:
undetectable		 4acbC-6ei1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 4 ILE A1465
ILE A1477
SER A1780
GLY A1536
 None
 0.82A 4acbC-6fb3A:
undetectable		 4acbC-6fb3A:
undetectable