SIMILAR PATTERNS OF AMINO ACIDS FOR 4ACA_C_DXCC1475

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cli PROTEIN
(PHOSPHORIBOSYL-AMIN
OIMIDAZOLE
SYNTHETASE)

(Escherichia
coli) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 ILE A 123
ILE A 126
PHE A 105
GLY A 158
 None
 0.82A 4acaC-1cliA:
undetectable		 4acaC-1cliA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d8c MALATE SYNTHASE G

(Escherichia
coli) 		PF01274
(Malate_synthase) 		4 ILE A 109
ASP A 106
ILE A 105
VAL A 100
 None
 0.76A 4acaC-1d8cA:
2.3		 4acaC-1d8cA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl2 CLASS I
ALPHA-1,2-MANNOSIDAS
E

(Saccharomyces
cerevisiae) 		PF01532
(Glyco_hydro_47) 		4 ILE A  83
ASP A  86
PHE A 499
GLN A 432
 None
None
GOL  A 900 (-3.3A)
None
 0.73A 4acaC-1dl2A:
undetectable		 4acaC-1dl2A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Escherichia
coli) 		PF02350
(Epimerase_2) 		4 ILE A 166
PHE A 146
SER A 103
GLY A 114
 None
 0.72A 4acaC-1f6dA:
4.3		 4acaC-1f6dA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hh2 N UTILIZATION
SUBSTANCE PROTEIN A

(Thermotoga
maritima) 		PF00575
(S1)
PF08529
(NusA_N)
PF13184
(KH_5) 		4 ILE P 336
ASP P 337
ILE P 338
GLY P 319
 None
 0.80A 4acaC-1hh2P:
undetectable		 4acaC-1hh2P:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i8q HYALURONATE LYASE

(Streptococcus
agalactiae) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 ILE A 880
ASP A 850
ILE A 851
PHE A 822
 None
 0.77A 4acaC-1i8qA:
undetectable		 4acaC-1i8qA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iub FUCOSE-SPECIFIC
LECTIN

(Aleuria
aurantia) 		PF07938
(Fungal_lectin) 		4 ILE A 276
ASP A 275
ILE A 274
GLY A 220
 None
 0.71A 4acaC-1iubA:
undetectable		 4acaC-1iubA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7y METHIONINE SYNTHASE

(Escherichia
coli) 		PF02310
(B12-binding)
PF02607
(B12-binding_2)
PF02965
(Met_synt_B12) 		4 ILE A 846
ILE A 832
VAL A 754
GLY A 805
 None
 0.71A 4acaC-1k7yA:
2.9		 4acaC-1k7yA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lj9 TRANSCRIPTIONAL
REGULATOR SLYA

(Enterococcus
faecalis) 		PF01047
(MarR) 		4 ILE A  50
ILE A  54
GLN A  32
GLY A  31
 None
 0.77A 4acaC-1lj9A:
undetectable		 4acaC-1lj9A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pzv PROBABLE
UBIQUITIN-CONJUGATIN
G ENZYME E2-19 KDA

(Caenorhabditis
elegans) 		PF00179
(UQ_con) 		4 ILE A  81
ILE A  76
VAL A  40
GLY A  42
 None
 0.59A 4acaC-1pzvA:
undetectable		 4acaC-1pzvA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1o CELL DIVISION
CONTROL PROTEIN 24

(Saccharomyces
cerevisiae) 		PF00564
(PB1) 		4 ILE A 798
ILE A 795
PHE A 791
GLY A 829
 None
 0.80A 4acaC-1q1oA:
undetectable		 4acaC-1q1oA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qcq PROTEIN (UBIQUITIN
CONJUGATING ENZYME)

(Saccharomyces
cerevisiae) 		PF00179
(UQ_con) 		4 ILE A  79
ILE A  74
SER A  21
GLY A  40
 None
 0.76A 4acaC-1qcqA:
undetectable		 4acaC-1qcqA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6b CLPA PROTEIN

(Escherichia
coli) 		PF00004
(AAA)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 ILE X 284
ASP X 285
ILE X 250
GLY X 256
 None
MG  X 782 (-3.7A)
None
None
 0.72A 4acaC-1r6bX:
undetectable		 4acaC-1r6bX:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9f PROTEIN 1D10

(Caenorhabditis
elegans) 		PF02815
(MIR) 		4 ILE A  94
ASP A  92
ILE A  88
GLY A  85
 None
 0.73A 4acaC-1t9fA:
undetectable		 4acaC-1t9fA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2e 2-HYDROXY-6-KETONONA
-2,4-DIENEDIOIC ACID
HYDROLASE

(Escherichia
coli) 		PF12697
(Abhydrolase_6) 		4 ILE A 229
VAL A 117
SER A  85
GLY A 113
 None
 0.76A 4acaC-1u2eA:
4.1		 4acaC-1u2eA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9p DNA LIGASE

(Thermus
filiformis) 		PF01653
(DNA_ligase_aden)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 ILE A 155
ILE A 158
VAL A 124
GLY A 136
 None
 0.75A 4acaC-1v9pA:
undetectable		 4acaC-1v9pA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz2 LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 ILE A 849
ASP A 845
ILE A 964
GLN A 956
 A  C 953 ( 4.0A)
G  C 954 ( 3.3A)
G  C 954 ( 4.5A)
None
 0.83A 4acaC-1wz2A:
undetectable		 4acaC-1wz2A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xvt CROTONOBETAINYL-COA:
CARNITINE
COA-TRANSFERASE

(Escherichia
coli) 		PF02515
(CoA_transf_3) 		4 ILE A 196
ASP A 197
ILE A 198
GLY A  26
 None
 0.52A 4acaC-1xvtA:
3.2		 4acaC-1xvtA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2asb TRANSCRIPTION
ELONGATION PROTEIN
NUSA

(Mycobacterium
tuberculosis) 		PF13184
(KH_5) 		4 ILE A 321
ASP A 322
ILE A 323
GLY A 304
 A  B  10 ( 4.6A)
U  B   9 ( 3.8A)
A  B   8 ( 3.9A)
C  B   6 ( 4.7A)
 0.82A 4acaC-2asbA:
undetectable		 4acaC-2asbA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cu0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF00478
(IMPDH)
PF00571
(CBS) 		4 ILE A  40
ASP A 352
ILE A 332
GLY A 274
 None
 0.83A 4acaC-2cu0A:
undetectable		 4acaC-2cu0A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dby GTP-BINDING PROTEIN

(Thermus
thermophilus) 		PF01926
(MMR_HSR1)
PF06071
(YchF-GTPase_C) 		4 ILE A 103
ILE A  97
VAL A  80
GLY A  78
 FMT  A 401 ( 4.7A)
None
None
None
 0.78A 4acaC-2dbyA:
10.0		 4acaC-2dbyA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dne DIHYDROLIPOYLLYSINE-
RESIDUE
ACETYLTRANSFERASE
COMPONENT OF
PYRUVATE
DEHYDROGENASE
COMPLEX

(Homo sapiens) 		PF00364
(Biotin_lipoyl) 		4 ILE A  41
ASP A  39
ILE A  35
GLY A  32
 None
 0.81A 4acaC-2dneA:
undetectable		 4acaC-2dneA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF) 		4 ILE A1075
ILE A1087
VAL A1135
GLY A1080
 None
 0.75A 4acaC-2eyqA:
undetectable		 4acaC-2eyqA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f4n HYPOTHETICAL PROTEIN
MJ1651

(Methanocaldococcus
jannaschii) 		PF01887
(SAM_adeno_trans) 		4 ILE A 203
ILE A 215
PHE A 230
VAL A 255
 None
 0.76A 4acaC-2f4nA:
3.0		 4acaC-2f4nA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h18 ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
8A

(Homo sapiens) 		PF00025
(Arf) 		4 ILE A 170
ASP A 168
ILE A 162
VAL A  93
 None
 0.74A 4acaC-2h18A:
13.4		 4acaC-2h18A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hj1 HYPOTHETICAL PROTEIN

(Haemophilus
influenzae) 		PF03658
(Ub-RnfH) 		4 ILE A  13
ILE A  15
PHE A  30
GLN A  44
 None
 0.56A 4acaC-2hj1A:
undetectable		 4acaC-2hj1A:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i34 ACID PHOSPHATASE

(Bacillus
anthracis) 		PF03767
(Acid_phosphat_B) 		4 ILE A 120
ILE A  62
PHE A 178
GLY A  44
 None
 0.76A 4acaC-2i34A:
3.1		 4acaC-2i34A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jep XYLOGLUCANASE

(Paenibacillus
pabuli) 		PF00150
(Cellulase) 		4 ILE A 176
ILE A 127
VAL A 357
GLY A  45
 None
 0.77A 4acaC-2jepA:
3.6		 4acaC-2jepA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2klx GLUTAREDOXIN

(Bartonella
henselae) 		PF00462
(Glutaredoxin) 		4 ILE A   4
ASP A  83
GLN A  54
GLY A  63
 None
 0.72A 4acaC-2klxA:
undetectable		 4acaC-2klxA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oua SERINE PROTEASE

(Nocardiopsis
alba) 		PF00089
(Trypsin) 		4 ASP A  15
ILE A  16
VAL A 106
GLY A 108
 None
 0.61A 4acaC-2ouaA:
3.0		 4acaC-2ouaA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pal PARVALBUMIN

(Esox lucius) 		PF13499
(EF-hand_7) 		4 ILE A  50
ASP A  51
ILE A  58
GLY A  89
 None
MN  A 111 ( 2.9A)
None
None
 0.76A 4acaC-2palA:
undetectable		 4acaC-2palA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE

(Escherichia
virus N4) 		no annotation 4 ILE A  12
ASP A  13
GLN A 150
GLY A  50
 None
 0.78A 4acaC-2po4A:
undetectable		 4acaC-2po4A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qx2 SEX PHEROMONE
STAPH-CAM373

(Staphylococcus
aureus) 		PF07537
(CamS) 		4 ILE A 373
ILE A 340
GLN A 345
GLY A 344
 None
None
None
EDO  A 402 ( 3.7A)
 0.79A 4acaC-2qx2A:
undetectable		 4acaC-2qx2A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qyv XAA-HIS DIPEPTIDASE

(Histophilus
somni) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ILE A 219
ASP A 218
SER A 361
GLY A 350
 None
 0.79A 4acaC-2qyvA:
2.5		 4acaC-2qyvA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r7m 5-FORMAMINOIMIDAZOLE
-4-CARBOXAMIDE-1-(BE
TA)-D-RIBOFURANOSYL
5'-MONOPHOSPHATE
SYNTHETASE

(Methanocaldococcus
jannaschii) 		PF06849
(DUF1246)
PF06973
(DUF1297) 		5 ILE A  78
ASP A  72
ILE A  73
PHE A  70
GLY A  25
 None
 1.36A 4acaC-2r7mA:
undetectable		 4acaC-2r7mA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y24 XYLANASE

(Dickeya
chrysanthemi) 		PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C) 		4 ILE A  35
ASP A  36
ILE A 325
GLY A 345
 None
 0.83A 4acaC-2y24A:
4.9		 4acaC-2y24A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zsg AMINOPEPTIDASE P,
PUTATIVE

(Thermotoga
maritima) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		4 ASP A 271
ILE A 305
VAL A 317
GLY A 302
 None
 0.77A 4acaC-2zsgA:
undetectable		 4acaC-2zsgA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE

(unidentified) 		PF01979
(Amidohydro_1) 		4 ILE A 318
ILE A 272
GLN A 296
GLY A 293
 None
 0.82A 4acaC-3be7A:
3.4		 4acaC-3be7A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Bacillus
anthracis) 		PF02350
(Epimerase_2) 		4 ILE A 171
PHE A 151
SER A 108
GLY A 119
 None
 0.75A 4acaC-3beoA:
7.4		 4acaC-3beoA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwk PENICILLIN-BINDING
PROTEIN 2

(Staphylococcus
aureus) 		PF00905
(Transpeptidase)
PF00912
(Transgly) 		4 ILE A 490
ASP A 489
VAL A 466
GLY A 471
 None
 0.76A 4acaC-3dwkA:
undetectable		 4acaC-3dwkA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzc UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Vibrio cholerae) 		PF02350
(Epimerase_2) 		4 ILE A 167
PHE A 147
SER A 104
GLY A 115
 None
 0.82A 4acaC-3dzcA:
6.6		 4acaC-3dzcA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0g LEUKEMIA INHIBITORY
FACTOR RECEPTOR

(Homo sapiens) 		PF00041
(fn3) 		4 ILE A 216
ASP A 215
ILE A 253
GLY A 279
 None
 0.77A 4acaC-3e0gA:
undetectable		 4acaC-3e0gA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE

(Escherichia
coli) 		PF00132
(Hexapep)
PF04613
(LpxD)
PF14602
(Hexapep_2) 		4 ASP A 232
VAL A 285
SER A 303
GLY A 287
 None
 0.76A 4acaC-3eh0A:
undetectable		 4acaC-3eh0A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gay FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Giardia
intestinalis) 		PF01116
(F_bP_aldolase) 		4 ILE A 238
ILE A 241
VAL A 254
GLY A  21
 None
None
P6T  A 327 (-4.3A)
None
 0.71A 4acaC-3gayA:
2.1		 4acaC-3gayA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gsi N,N-DIMETHYLGLYCINE
OXIDASE

(Arthrobacter
globiformis) 		PF01266
(DAO)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF16350
(FAO_M) 		4 ILE A 804
ASP A 803
ILE A 811
GLY A 754
 None
 0.67A 4acaC-3gsiA:
4.3		 4acaC-3gsiA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h8w RIBONUCLEASE H

(Escherichia
virus T4) 		PF02739
(5_3_exonuc_N)
PF09293
(RNaseH_C) 		4 ILE A 152
ASP A  19
ILE A  23
PHE A  20
 None
 0.68A 4acaC-3h8wA:
undetectable		 4acaC-3h8wA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h9j MCCB PROTEIN

(Escherichia
coli) 		PF00899
(ThiF) 		4 ILE A 139
ILE A 142
VAL A 210
GLY A 127
 None
 0.83A 4acaC-3h9jA:
3.3		 4acaC-3h9jA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hag CAPSID PROTEIN

(Orthohepevirus
A) 		PF03014
(SP2) 		4 ILE A 280
ILE A 207
VAL A 198
GLY A 239
 None
 0.82A 4acaC-3hagA:
undetectable		 4acaC-3hagA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j1c CHAPERONIN ALPHA
SUBUNIT

(Acidianus
tengchongensis) 		PF00118
(Cpn60_TCP1) 		4 ILE A 226
ILE A 370
VAL A 248
GLY A 352
 None
 0.78A 4acaC-3j1cA:
undetectable		 4acaC-3j1cA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jtg ETS-RELATED
TRANSCRIPTION FACTOR
ELF-3

(Mus musculus) 		PF00178
(Ets) 		4 ILE A 282
ASP A 281
GLN A 317
GLY A 316
 None
 0.73A 4acaC-3jtgA:
undetectable		 4acaC-3jtgA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kxq TRIOSEPHOSPHATE
ISOMERASE

(Bartonella
henselae) 		PF00121
(TIM) 		4 ASP A  81
ILE A  82
GLN A  68
GLY A  67
 None
 0.81A 4acaC-3kxqA:
3.4		 4acaC-3kxqA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n2c PROLIDASE

(unidentified) 		PF01979
(Amidohydro_1) 		4 ILE A 187
ILE A 215
VAL A 166
GLY A 171
 KCX  A 188 ( 3.6A)
None
None
None
 0.70A 4acaC-3n2cA:
3.3		 4acaC-3n2cA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nv9 MALIC ENZYME

(Entamoeba
histolytica) 		PF00390
(malic)
PF03949
(Malic_M) 		4 ILE A 322
PHE A 324
SER A 387
GLY A 205
 None
 0.80A 4acaC-3nv9A:
3.9		 4acaC-3nv9A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 ILE A 237
ASP A 238
PHE A 251
VAL A 191
 None
 0.83A 4acaC-3szeA:
2.5		 4acaC-3szeA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 ILE A 717
PHE A 704
VAL A 729
GLY A 707
 None
 0.83A 4acaC-3szeA:
2.5		 4acaC-3szeA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t2n SERINE PROTEASE
HEPSIN

(Homo sapiens) 		PF00089
(Trypsin)
PF09272
(Hepsin-SRCR) 		4 ILE A 258
ASP A 257
ILE A 374
GLY A 190
 None
 0.81A 4acaC-3t2nA:
undetectable		 4acaC-3t2nA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tx1 UDP-N-ACETYLENOLPYRU
VOYLGLUCOSAMINE
REDUCTASE

(Listeria
monocytogenes) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		4 ILE A  73
ILE A  68
SER A 125
GLY A  63
 None
None
FAD  A 299 (-2.8A)
FAD  A 299 (-3.0A)
 0.67A 4acaC-3tx1A:
undetectable		 4acaC-3tx1A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uto TWITCHIN

(Caenorhabditis
elegans) 		PF00041
(fn3)
PF00069
(Pkinase)
PF07679
(I-set) 		4 ILE A 296
ASP A 297
ILE A 452
GLY A 163
 None
 0.82A 4acaC-3utoA:
undetectable		 4acaC-3utoA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uv1 DER F 7 ALLERGEN

(Dermatophagoides
farinae) 		PF16984
(Grp7_allergen) 		4 ILE A  29
ASP A  30
VAL A 123
GLY A  89
 None
 0.81A 4acaC-3uv1A:
undetectable		 4acaC-3uv1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vly NITRITE REDUCTASE

(Nicotiana
tabacum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 ILE A 396
ILE A 404
VAL A 376
GLY A 374
 None
None
None
K  A 603 ( 4.6A)
 0.80A 4acaC-3vlyA:
undetectable		 4acaC-3vlyA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vyl L-RIBULOSE
3-EPIMERASE

(Mesorhizobium
loti) 		PF01261
(AP_endonuc_2) 		5 ILE A 220
ASP A 221
ILE A 225
PHE A 226
VAL A 205
 None
 1.46A 4acaC-3vylA:
2.0		 4acaC-3vylA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ypi TRIOSEPHOSPHATE
ISOMERASE

(Saccharomyces
cerevisiae) 		PF00121
(TIM) 		4 ASP A 242
ILE A 243
PHE A 240
GLY A   9
 None
 0.78A 4acaC-3ypiA:
3.4		 4acaC-3ypiA:
20.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4aca TRANSLATION
ELONGATION FACTOR
SELB

(Methanococcus
maripaludis) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		5 PHE A  51
VAL A 202
SER A 231
GLN A 233
GLY A 249
 None
 0.55A 4acaC-4acaA:
51.8		 4acaC-4acaA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP

(Thermotoga
maritima) 		PF03030
(H_PPase) 		4 ILE A 256
VAL A 144
GLN A 154
GLY A 149
 None
 0.80A 4acaC-4av6A:
undetectable		 4acaC-4av6A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bz4 COPPER-REPRESSIBLE
POLYPEPTIDE

(Methylomicrobium
album) 		no annotation 4 ILE A 122
ASP A 121
VAL A 195
GLN A 118
 None
 0.74A 4acaC-4bz4A:
undetectable		 4acaC-4bz4A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c2f CARBOXY-TERMINAL
PROCESSING PROTEASE
CTPB

(Bacillus
subtilis) 		PF01471
(PG_binding_1)
PF03572
(Peptidase_S41)
PF13180
(PDZ_2) 		4 ILE A 147
ILE A 179
PHE A 190
GLY A 140
 None
 0.75A 4acaC-4c2fA:
2.6		 4acaC-4c2fA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dk1 PUTATIVE MACA,
MULTIDRUG RESISTANCE
PROTEIN MEXA

(Pseudomonas
aeruginosa;
Aggregatibacter
actinomycetemcomitans) 		PF16576
(HlyD_D23) 		4 ILE A 227
ASP A 228
ILE A 249
GLY A  50
 None
 0.79A 4acaC-4dk1A:
3.8		 4acaC-4dk1A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dpy MEVALONATE
DIPHOSPHATE
DECARBOXYLASE

(Staphylococcus
epidermidis) 		PF00288
(GHMP_kinases_N) 		5 ILE A  92
ASP A  56
ILE A  73
SER A 141
GLY A 138
 None
None
None
2P0  A 401 (-2.7A)
None
 1.45A 4acaC-4dpyA:
undetectable		 4acaC-4dpyA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ga6 PUTATIVE THYMIDINE
PHOSPHORYLASE

(Thermococcus
kodakarensis) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C) 		4 ILE A 428
ASP A 429
ILE A 433
GLY A 171
 None
 0.73A 4acaC-4ga6A:
3.3		 4acaC-4ga6A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM)
PF07496
(zf-CW) 		4 ILE A 781
ASP A 780
GLN A 503
GLY A 774
 None
 0.79A 4acaC-4hsuA:
undetectable		 4acaC-4hsuA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA

(Planctopirus
limnophila) 		PF00575
(S1)
PF08529
(NusA_N)
PF13184
(KH_5)
PF14520
(HHH_5) 		4 ASP A  73
VAL A   6
SER A  54
GLY A   3
 None
 0.81A 4acaC-4mtnA:
undetectable		 4acaC-4mtnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA

(Planctopirus
limnophila) 		PF00575
(S1)
PF08529
(NusA_N)
PF13184
(KH_5)
PF14520
(HHH_5) 		4 ILE A  74
ASP A  73
SER A  54
GLY A   3
 None
 0.81A 4acaC-4mtnA:
undetectable		 4acaC-4mtnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ncn EUKARYOTIC
TRANSLATION
INITIATION FACTOR
5B-LIKE PROTEIN

(Chaetomium
thermophilum) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		4 ILE A 592
ASP A 594
ILE A 528
VAL A 644
 None
MG  A1002 ( 4.1A)
None
None
 0.75A 4acaC-4ncnA:
19.2		 4acaC-4ncnA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pq0 FACT COMPLEX SUBUNIT
POB3

(Saccharomyces
cerevisiae) 		PF08512
(Rtt106) 		4 ILE A 266
ASP A 260
ILE A 261
PHE A 245
 None
 0.72A 4acaC-4pq0A:
undetectable		 4acaC-4pq0A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rp8 ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA

(Escherichia
coli) 		PF03611
(EIIC-GAT) 		4 ILE A  83
ILE A 354
VAL A  70
GLN A 337
 None
 0.79A 4acaC-4rp8A:
undetectable		 4acaC-4rp8A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u0z ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FICD

(Homo sapiens) 		PF02661
(Fic) 		4 ILE A 156
ASP A 155
ILE A 157
SER A 196
 None
 0.80A 4acaC-4u0zA:
undetectable		 4acaC-4u0zA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbj BLR1131 PROTEIN

(Bradyrhizobium
diazoefficiens) 		PF02630
(SCO1-SenC) 		4 ILE A 102
ILE A  67
VAL A 140
GLY A  42
 None
 0.76A 4acaC-4wbjA:
2.3		 4acaC-4wbjA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a2o NITRATE TRANSPORTER
1.1

(Arabidopsis
thaliana) 		PF00854
(PTR2) 		4 ILE A 197
PHE A 190
VAL A 167
GLY A 171
 None
 0.81A 4acaC-5a2oA:
undetectable		 4acaC-5a2oA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7m BETA-XYLOSIDASE

(Trichoderma
reesei) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 ILE A 458
ILE A 489
VAL A 529
GLY A 527
 None
 0.81A 4acaC-5a7mA:
6.0		 4acaC-5a7mA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE

(Sulfolobus
acidocaldarius) 		no annotation 4 ILE A 157
ASP A 159
VAL A 131
GLY A  95
 None
 0.78A 4acaC-5a7tA:
undetectable		 4acaC-5a7tA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b6t GLYCOSYL HYDROLASE
FAMILY 62 PROTEIN

(Coprinopsis
cinerea) 		PF03664
(Glyco_hydro_62) 		4 ILE A 283
ASP A 284
ILE A 360
GLN A 392
 None
 0.77A 4acaC-5b6tA:
undetectable		 4acaC-5b6tA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5by3 BTGH115A

(Bacteroides
thetaiotaomicron) 		PF15979
(Glyco_hydro_115) 		4 ILE A  84
ASP A  85
ILE A  86
GLY A  74
 None
 0.80A 4acaC-5by3A:
undetectable		 4acaC-5by3A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		PF12625
(Arabinose_bd)
PF12833
(HTH_18) 		4 ILE A 105
ASP A 118
ILE A 119
PHE A 189
 None
 0.74A 4acaC-5chhA:
undetectable		 4acaC-5chhA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzt CYLM

(Enterococcus
faecalis) 		PF05147
(LANC_like)
PF13575
(DUF4135) 		4 ILE A 354
ILE A 363
VAL A 272
GLN A 250
 None
AMP  A1002 ( 3.9A)
AMP  A1002 (-4.6A)
AMP  A1002 (-3.3A)
 0.83A 4acaC-5dztA:
undetectable		 4acaC-5dztA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fei DISTAL TUBE PROTEIN

(Bacillus virus
phi29) 		PF16838
(Caud_tail_N) 		4 ILE A  13
ILE A  78
PHE A 109
VAL A  51
 None
 0.78A 4acaC-5feiA:
2.5		 4acaC-5feiA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ido 3' TERMINAL URIDYLYL
TRANSFERASE

(Trypanosoma
brucei) 		PF03828
(PAP_assoc) 		4 ILE A 295
ASP A 312
ILE A 311
GLY A 307
 None
UTP  A 701 ( 4.7A)
None
None
 0.61A 4acaC-5idoA:
undetectable		 4acaC-5idoA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j49 UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE

(Paraburkholderia
xenovorans) 		PF00483
(NTP_transferase) 		4 ILE A 235
ILE A 158
VAL A 129
GLY A 206
 None
 0.81A 4acaC-5j49A:
undetectable		 4acaC-5j49A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jld ARGINYL-TRNA
SYNTHETASE, PUTATIVE

(Plasmodium
falciparum) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		4 ILE A 121
ILE A 116
PHE A 519
VAL A 161
 None
 0.82A 4acaC-5jldA:
3.2		 4acaC-5jldA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kh0 SMALL GTP-BINDING
PROTEIN

(Thermosipho
melanesiensis) 		PF01926
(MMR_HSR1) 		4 ILE A 294
ILE A 347
SER A 243
GLY A 377
 None
 0.78A 4acaC-5kh0A:
15.7		 4acaC-5kh0A:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE GAMMA
SUBUNIT

(Aromatoleum
aromaticum) 		PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		4 ILE B  15
ASP B  14
ILE B  13
GLY B  56
 None
 0.66A 4acaC-5l9wB:
3.6		 4acaC-5l9wB:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN

(Escherichia
coli) 		PF00258
(Flavodoxin_1)
PF00301
(Rubredoxin)
PF00753
(Lactamase_B) 		4 ILE A  72
ASP A  71
ILE A  67
VAL A  12
 None
 0.78A 4acaC-5lmcA:
7.7		 4acaC-5lmcA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mp4 PROTOPLAST SECRETED
PROTEIN 2

(Saccharomyces
cerevisiae) 		PF03358
(FMN_red) 		4 ILE A   8
ILE A   6
GLN A 187
GLY A 188
 None
 0.79A 4acaC-5mp4A:
5.0		 4acaC-5mp4A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n94 CG9323, ISOFORM A

(Drosophila
melanogaster) 		no annotation 4 ASP A 499
ILE A 498
PHE A 475
GLY A 469
 None
 0.81A 4acaC-5n94A:
3.5		 4acaC-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npy FLAGELLAR BASAL BODY
PROTEIN

(Helicobacter
pylori) 		no annotation 4 ILE A 484
ILE A 490
VAL A 144
GLY A 146
 None
 0.81A 4acaC-5npyA:
undetectable		 4acaC-5npyA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5osn CAPSID PROTEIN
CAPSID PROTEIN

(Enterovirus E;
Enterovirus E) 		PF00073
(Rhv)
PF00073
(Rhv) 		4 ILE C  34
ASP C  35
ILE C  36
GLY A 239
 None
 0.76A 4acaC-5osnC:
undetectable		 4acaC-5osnC:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uak CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR

(Homo sapiens) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane)
PF14396
(CFTR_R) 		4 ILE A 991
ILE A 995
VAL A 862
GLY A 934
 None
 0.69A 4acaC-5uakA:
undetectable		 4acaC-5uakA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgt SINGLE-STRANDED
DNA-BINDING PROTEIN

(Staphylococcus
aureus) 		PF00436
(SSB) 		4 VAL A   6
SER A  99
GLN A 101
GLY A  72
 None
 0.62A 4acaC-5xgtA:
undetectable		 4acaC-5xgtA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d0p PIRIN FAMILY PROTEIN

(Acinetobacter
baumannii) 		no annotation 4 ILE A 148
ASP A 147
ILE A 143
VAL A  69
 None
 0.81A 4acaC-6d0pA:
undetectable		 4acaC-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ekg CHEMOTAXIS PROTEIN
CHEY

(Methanococcus
maripaludis) 		no annotation 4 ILE Y  79
ILE Y  81
VAL Y  10
GLY Y  65
 None
 0.82A 4acaC-6ekgY:
8.1		 4acaC-6ekgY:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 4 ILE A1465
ILE A1477
SER A1780
GLY A1536
 None
 0.81A 4acaC-6fb3A:
undetectable		 4acaC-6fb3A:
undetectable