SIMILAR PATTERNS OF AMINO ACIDS FOR 4AC9_C_DXCC1478_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a2o CHEB METHYLESTERASE

(Salmonella
enterica) 		PF00072
(Response_reg)
PF01339
(CheB_methylest) 		4 ASP A 286
GLY A 282
THR A 165
SER A 259
 None
 1.05A 4ac9C-1a2oA:
8.2		 4ac9C-1a2oA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1adq IGM-LAMBDA RF-AN FAB
(HEAVY CHAIN)

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ASP H 197
GLY H 201
THR H 202
SER H 195
 None
 0.91A 4ac9C-1adqH:
undetectable		 4ac9C-1adqH:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fq9 FIBROBLAST GROWTH
FACTOR RECEPTOR 1

(Homo sapiens) 		PF07679
(I-set) 		4 ASP C 335
THR C 266
SER C 332
PHE C 333
 None
 0.75A 4ac9C-1fq9C:
undetectable		 4ac9C-1fq9C:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gmm CBM6

(Ruminiclostridium
thermocellum) 		PF03422
(CBM_6) 		4 GLY A  82
SER A 116
THR A  67
PHE A 115
 None
 1.05A 4ac9C-1gmmA:
undetectable		 4ac9C-1gmmA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gwc GLUTATHIONE
S-TRANSFERASE TSI-1

(Aegilops
tauschii) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 ASP A 185
THR A 175
THR A 189
PHE A 184
 None
 1.03A 4ac9C-1gwcA:
undetectable		 4ac9C-1gwcA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyc LACCASE 2

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ASP A  18
GLY A 173
SER A 177
THR A 180
 None
 1.02A 4ac9C-1gycA:
undetectable		 4ac9C-1gycA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ih5 AQUAPORIN-1

(Homo sapiens) 		PF00230
(MIP) 		4 GLY A 145
THR A 146
SER A  53
PHE A  56
 None
 0.87A 4ac9C-1ih5A:
undetectable		 4ac9C-1ih5A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j2q PROTEASOME ALPHA
SUBUNIT

(Archaeoglobus
fulgidus) 		PF00227
(Proteasome)
PF10584
(Proteasome_A_N) 		4 ASP A 188
GLY A 193
SER A 185
PHE A 186
 None
 1.03A 4ac9C-1j2qA:
undetectable		 4ac9C-1j2qA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpy CATECHOL
2,3-DIOXYGENASE

(Pseudomonas
putida) 		PF00903
(Glyoxalase) 		4 SER A 193
ASP A 200
GLY A 173
THR A 169
 None
 1.04A 4ac9C-1mpyA:
undetectable		 4ac9C-1mpyA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis omega
virus) 		PF03566
(Peptidase_A21) 		4 ASP A 195
GLY A 292
THR A 400
SER A 192
 None
 0.99A 4ac9C-1ohfA:
undetectable		 4ac9C-1ohfA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ojz ADP-RIBOSYLTRANSFERA
SE

(Staphylococcus
aureus) 		PF03496
(ADPrib_exo_Tox) 		4 SER A  80
ASP A  79
GLY A 161
THR A 162
 None
 0.98A 4ac9C-1ojzA:
undetectable		 4ac9C-1ojzA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1onf GLUTATHIONE
REDUCTASE

(Plasmodium
falciparum) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 SER A  33
GLY A  37
THR A  38
THR A 109
 FAD  A 500 ( 4.0A)
FAD  A 500 ( 3.7A)
FAD  A 500 (-3.6A)
FAD  A 500 (-4.2A)
 1.04A 4ac9C-1onfA:
undetectable		 4ac9C-1onfA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1op2 VENOM SERINE
PROTEINASE

(Deinagkistrodon
acutus) 		PF00089
(Trypsin) 		4 ASP A 194
GLY A  44
THR A  45
THR A 190
 None
 0.87A 4ac9C-1op2A:
undetectable		 4ac9C-1op2A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qaf PROTEIN (COPPER
AMINE OXIDASE)

(Escherichia
coli) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3)
PF07833
(Cu_amine_oxidN1) 		4 THR A  47
SER A  71
THR A  73
PHE A  74
 None
 0.98A 4ac9C-1qafA:
undetectable		 4ac9C-1qafA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r66 TDP-GLUCOSE-4,6-DEHY
DRATASE

(Streptomyces
venezuelae) 		PF16363
(GDP_Man_Dehyd) 		4 GLY A 106
THR A 107
SER A  38
THR A  40
 None
None
NAD  A 900 (-3.2A)
NAD  A 900 (-3.3A)
 0.69A 4ac9C-1r66A:
5.5		 4ac9C-1r66A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rw9 CHONDROITIN AC LYASE

(Paenarthrobacter
aurescens) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 SER A 399
ASP A 383
THR A 419
SER A 400
 None
 0.97A 4ac9C-1rw9A:
undetectable		 4ac9C-1rw9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rzr GLUCOSE-RESISTANCE
AMYLASE REGULATOR

(Bacillus
megaterium) 		no annotation 4 ASP G 248
GLY G 253
SER G 280
THR G 277
 None
 0.85A 4ac9C-1rzrG:
3.0		 4ac9C-1rzrG:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sqj OLIGOXYLOGLUCAN
REDUCING-END-SPECIFI
C CELLOBIOHYDROLASE

(Geotrichum sp.
M128) 		PF15899
(BNR_6) 		4 ASP A  60
GLY A  65
THR A  66
THR A 783
 None
 1.02A 4ac9C-1sqjA:
undetectable		 4ac9C-1sqjA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1taq TAQ DNA POLYMERASE

(Thermus
aquaticus) 		PF00476
(DNA_pol_A)
PF01367
(5_3_exonuc)
PF02739
(5_3_exonuc_N)
PF09281
(Taq-exonuc) 		4 SER A 242
ASP A 244
GLY A 187
THR A 186
 None
 0.96A 4ac9C-1taqA:
undetectable		 4ac9C-1taqA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tlf LAC REPRESSOR

(Escherichia
coli) 		PF13377
(Peripla_BP_3) 		4 ASP A 247
GLY A 252
SER A 279
THR A 276
 None
 0.68A 4ac9C-1tlfA:
3.9		 4ac9C-1tlfA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tly NUCLEOSIDE-SPECIFIC
CHANNEL-FORMING
PROTEIN TSX

(Escherichia
coli) 		PF03502
(Channel_Tsx) 		4 SER A  85
GLY A 128
THR A 129
THR A  90
 None
 0.79A 4ac9C-1tlyA:
undetectable		 4ac9C-1tlyA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fml MUTT/NUDIX FAMILY
PROTEIN

(Enterococcus
faecalis) 		PF00293
(NUDIX) 		4 SER A  88
ASP A  87
THR A  93
SER A  84
 None
 0.92A 4ac9C-2fmlA:
undetectable		 4ac9C-2fmlA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2isn NYSGXRC-8828Z,
PHOSPHATASE

(Toxoplasma
gondii) 		PF00481
(PP2C) 		4 ASP A  29
GLY A 105
SER A 326
THR A  19
 None
 1.00A 4ac9C-2isnA:
undetectable		 4ac9C-2isnA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ong 4S-LIMONENE SYNTHASE

(Mentha spicata) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 SER A 552
ASP A 551
THR A 474
SER A 549
 None
 0.92A 4ac9C-2ongA:
undetectable		 4ac9C-2ongA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p11 HYPOTHETICAL PROTEIN

(Paraburkholderia
xenovorans) 		no annotation 4 ASP A 167
THR A 185
THR A  20
PHE A  15
 None
 1.01A 4ac9C-2p11A:
2.2		 4ac9C-2p11A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2paf LACTOSE OPERON
REPRESSOR

(Escherichia
coli) 		PF13377
(Peripla_BP_3) 		4 ASP A 247
GLY A 252
SER A 279
THR A 276
 None
 0.65A 4ac9C-2pafA:
5.4		 4ac9C-2pafA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pff FATTY ACID SYNTHASE
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00106
(adh_short)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 SER A1643
GLY A1543
THR A1544
THR A1427
 None
 1.05A 4ac9C-2pffA:
2.2		 4ac9C-2pffA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w7y PROBABLE SUGAR ABC
TRANSPORTER,
SUGAR-BINDING
PROTEIN

(Streptococcus
pneumoniae) 		PF13416
(SBP_bac_8) 		4 SER A 305
GLY A 308
SER A 304
THR A 385
 None
 0.95A 4ac9C-2w7yA:
undetectable		 4ac9C-2w7yA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2we8 XANTHINE
DEHYDROGENASE

(Mycolicibacterium
smegmatis) 		PF02625
(XdhC_CoxI)
PF13478
(XdhC_C) 		4 GLY A  25
THR A  26
THR A 110
PHE A 111
 None
 1.03A 4ac9C-2we8A:
7.4		 4ac9C-2we8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zat DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Sus scrofa) 		PF13561
(adh_short_C2) 		4 GLY A 153
SER A 202
THR A 199
PHE A 201
 None
NAP  A1261 ( 3.4A)
NAP  A1261 ( 2.7A)
NAP  A1261 ( 4.9A)
 0.61A 4ac9C-2zatA:
6.4		 4ac9C-2zatA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbw THIOREDOXIN
REDUCTASE

(Thermus
thermophilus) 		PF07992
(Pyr_redox_2) 		4 ASP A   7
SER A  30
THR A   6
PHE A  31
 None
 1.03A 4ac9C-2zbwA:
undetectable		 4ac9C-2zbwA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ai5 YEAST ENHANCED GREEN
FLUORESCENT
PROTEIN,UBIQUITIN

(Aequorea
victoria;
Mus musculus) 		PF00240
(ubiquitin)
PF01353
(GFP) 		4 ASP A  19
THR A 108
SER A  28
PHE A  27
 None
 1.03A 4ac9C-3ai5A:
undetectable		 4ac9C-3ai5A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ako VENUS

(Plant
transformation
vector
pSITEII-4C1) 		PF01353
(GFP) 		4 ASP A  19
THR A 108
SER A  28
PHE A  27
 None
 1.06A 4ac9C-3akoA:
undetectable		 4ac9C-3akoA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cqb PROBABLE PROTEASE
HTPX HOMOLOG

(Vibrio
parahaemolyticus) 		PF01435
(Peptidase_M48) 		4 GLY A  70
THR A  69
THR A  98
PHE A  54
 None
 1.03A 4ac9C-3cqbA:
undetectable		 4ac9C-3cqbA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria) 		PF01353
(GFP) 		4 ASP A 177
THR A 266
SER A 186
PHE A 185
 None
 1.03A 4ac9C-3evpA:
undetectable		 4ac9C-3evpA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ivu HOMOCITRATE
SYNTHASE,
MITOCHONDRIAL

(Schizosaccharomyces
pombe) 		PF00682
(HMGL-like) 		4 SER A 166
GLY A 127
THR A 128
THR A 197
 None
None
None
AKG  A1000 (-2.9A)
 0.65A 4ac9C-3ivuA:
3.6		 4ac9C-3ivuA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyp COMPLEMENT
DECAY-ACCELERATING
FACTOR

(Homo sapiens) 		PF00084
(Sushi) 		4 ASP F 143
GLY F 147
SER F 155
PHE F 156
 None
 1.01A 4ac9C-3iypF:
undetectable		 4ac9C-3iypF:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9o INTRACELLULAR GROWTH
LOCUS PROTEIN B

(Francisella
tularensis) 		PF05943
(VipB) 		4 ASP B 201
GLY B 248
SER B 203
PHE B 204
 None
 0.91A 4ac9C-3j9oB:
2.6		 4ac9C-3j9oB:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9b LIVER
CARBOXYLESTERASE 1

(Homo sapiens) 		PF00135
(COesterase) 		4 SER A1179
GLY A1320
THR A1321
SER A1185
 None
 0.77A 4ac9C-3k9bA:
2.7		 4ac9C-3k9bA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l4c DEDICATOR OF
CYTOKINESIS PROTEIN
1

(Homo sapiens) 		PF14429
(DOCK-C2) 		4 ASP A 550
GLY A 547
THR A 606
PHE A 602
 None
 1.02A 4ac9C-3l4cA:
undetectable		 4ac9C-3l4cA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l6c SERINE RACEMASE

(Rattus
norvegicus) 		PF00291
(PALP) 		4 ASP A  11
GLY A 162
SER A   8
PHE A   9
 None
 0.99A 4ac9C-3l6cA:
2.8		 4ac9C-3l6cA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l6r SERINE RACEMASE

(Homo sapiens) 		PF00291
(PALP) 		4 ASP A  11
GLY A 162
SER A   8
PHE A   9
 None
 0.93A 4ac9C-3l6rA:
3.5		 4ac9C-3l6rA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465

(Oleispira
antarctica) 		PF01979
(Amidohydro_1) 		4 SER A 252
THR A 257
THR A 247
PHE A 249
 None
 0.75A 4ac9C-3lnpA:
2.2		 4ac9C-3lnpA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN

(Escherichia
coli;
Aequorea
victoria) 		PF01353
(GFP)
PF01547
(SBP_bac_1)
PF13416
(SBP_bac_8) 		4 ASP A 293
THR A 382
SER A 302
PHE A 301
 None
 1.02A 4ac9C-3osqA:
undetectable		 4ac9C-3osqA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN

(Escherichia
coli;
Aequorea
victoria) 		PF01353
(GFP)
PF01547
(SBP_bac_1) 		4 ASP A 431
THR A 520
SER A 440
PHE A 439
 None
 1.04A 4ac9C-3osrA:
undetectable		 4ac9C-3osrA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3otd TRNA(HIS)
GUANYLYLTRANSFERASE

(Homo sapiens) 		PF04446
(Thg1)
PF14413
(Thg1C) 		4 ASP A 251
GLY A 209
THR A 210
PHE A 257
 None
None
IOD  A 270 ( 4.6A)
None
 0.68A 4ac9C-3otdA:
undetectable		 4ac9C-3otdA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqg METHYL-COENZYME M
REDUCTASE, GAMMA
SUBUNIT

(uncultured
archaeon) 		PF02240
(MCR_gamma) 		4 ASP C  89
GLY C 157
SER C  94
THR C  97
 None
 1.05A 4ac9C-3sqgC:
undetectable		 4ac9C-3sqgC:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suc PRENECK APPENDAGE
PROTEIN

(Bacillus virus
phi29) 		PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3) 		4 ASP A 280
GLY A 276
THR A 275
PHE A 309
 CA  A   1 (-2.5A)
None
None
None
 1.06A 4ac9C-3sucA:
undetectable		 4ac9C-3sucA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 ASP A 551
GLY A 632
THR A 552
PHE A 636
 None
 0.74A 4ac9C-3szeA:
2.5		 4ac9C-3szeA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tf7 42F3 MUT7 SCFV (42F3
ALPHA CHAIN, LINKER,
42F3 BETA CHAIN)

(Mus musculus) 		PF07686
(V-set) 		4 SER C  71
ASP C  70
SER C  72
PHE C  66
 None
 0.92A 4ac9C-3tf7C:
undetectable		 4ac9C-3tf7C:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr5 PEPTIDE CHAIN
RELEASE FACTOR 3

(Coxiella
burnetii) 		PF00009
(GTP_EFTU)
PF16658
(RF3_C) 		4 ASP A 142
GLY A 171
SER A 254
PHE A 259
 GDP  A 527 (-2.7A)
None
GDP  A 527 (-3.0A)
None
 0.86A 4ac9C-3tr5A:
15.6		 4ac9C-3tr5A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tw5 TRANSGLUTAMINASE
ELICITOR

(Phytophthora
sojae) 		PF16683
(TGase_elicitor) 		4 SER A 249
ASP A 248
GLY A 252
SER A 242
 None
 1.04A 4ac9C-3tw5A:
undetectable		 4ac9C-3tw5A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4j NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF00171
(Aldedh) 		4 SER A 199
GLY A  51
THR A  52
SER A 195
 None
 0.96A 4ac9C-3u4jA:
4.7		 4ac9C-3u4jA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u8p CYTOCHROME B562
INTEGRAL FUSION WITH
ENHANCED GREEN
FLUORESCENT PROTEIN

(Escherichia
coli;
Aequorea
victoria) 		PF01353
(GFP)
PF07361
(Cytochrom_B562) 		4 ASP A  19
THR A 216
SER A  28
PHE A  27
 None
 1.05A 4ac9C-3u8pA:
undetectable		 4ac9C-3u8pA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ue3 SEPTUM FORMATION,
PENICILLIN BINDING
PROTEIN 3,
PEPTIDOGLYCAN
SYNTHETASE

(Acinetobacter
sp. ATCC 27244) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 SER A 395
GLY A 444
THR A 445
SER A 391
 None
 0.95A 4ac9C-3ue3A:
undetectable		 4ac9C-3ue3A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v0a LLAMA ANTIBODY F12

(Lama glama) 		PF07686
(V-set) 		4 ASP C 102
GLY C  98
THR C  97
PHE C  45
 SO4  C 144 ( 4.6A)
None
None
None
 0.78A 4ac9C-3v0aC:
undetectable		 4ac9C-3v0aC:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpx LEUCINE
DEHYDROGENASE

(Sporosarcina
psychrophila) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ASP A 122
GLY A 135
THR A 134
PHE A  99
 None
 1.06A 4ac9C-3vpxA:
undetectable		 4ac9C-3vpxA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr1 PEPTIDE CHAIN
RELEASE FACTOR 3

(Desulfovibrio
vulgaris) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF16658
(RF3_C) 		4 ASP A 144
GLY A 173
SER A 256
PHE A 261
 G4P  A 601 (-2.9A)
None
G4P  A 601 (-3.3A)
None
 0.81A 4ac9C-3vr1A:
16.9		 4ac9C-3vr1A:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zjk BETA GLYCOSIDASE

(Thermus
thermophilus) 		PF00232
(Glyco_hydro_1) 		4 ASP A  45
GLY A  41
THR A 398
PHE A 395
 None
 0.84A 4ac9C-3zjkA:
3.4		 4ac9C-3zjkA:
21.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4aca TRANSLATION
ELONGATION FACTOR
SELB

(Methanococcus
maripaludis) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		6 SER A 121
ASP A 122
GLY A 125
THR A 126
SER A 155
THR A 158
 None
 0.40A 4ac9C-4acaA:
51.9		 4ac9C-4acaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4aca TRANSLATION
ELONGATION FACTOR
SELB

(Methanococcus
maripaludis) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		5 SER A 121
ASP A 122
SER A 155
THR A 158
PHE A 160
 None
 0.42A 4ac9C-4acaA:
51.9		 4ac9C-4acaA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aov ISOCITRATE
DEHYDROGENASE [NADP]

(Desulfotalea
psychrophila) 		PF00180
(Iso_dh) 		4 SER A 354
ASP A 353
THR A 359
PHE A 351
 None
 1.04A 4ac9C-4aovA:
2.1		 4ac9C-4aovA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bju N-ACETYLGLUCOSAMINE-
PHOSPHATE MUTASE

(Aspergillus
fumigatus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		4 ASP A 374
GLY A 333
SER A 390
PHE A 389
 None
 0.95A 4ac9C-4bjuA:
undetectable		 4ac9C-4bjuA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4buc UDP-N-ACETYLMURAMOYL
ALANINE--D-GLUTAMATE
LIGASE

(Thermotoga
maritima) 		PF08245
(Mur_ligase_M) 		4 SER A 177
GLY A 129
THR A 130
PHE A 179
 None
None
PO4  A1000 ( 4.4A)
PO4  A1000 (-4.6A)
 0.92A 4ac9C-4bucA:
4.8		 4ac9C-4bucA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3s ALDEHYDE
DEHYDROGENASE

(Lachnoclostridium
phytofermentans) 		PF00171
(Aldedh) 		4 GLY A 438
THR A 437
SER A 443
PHE A 447
 None
 1.00A 4ac9C-4c3sA:
2.4		 4ac9C-4c3sA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e7n SNAKE-VENOM
THROMBIN-LIKE ENZYME

(Gloydius halys) 		PF00089
(Trypsin) 		4 ASP A 194
GLY A  44
THR A  45
THR A 190
 None
 1.05A 4ac9C-4e7nA:
undetectable		 4ac9C-4e7nA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4exq UROPORPHYRINOGEN
DECARBOXYLASE

(Burkholderia
thailandensis) 		PF01208
(URO-D) 		4 ASP A 214
GLY A 274
SER A 153
THR A 156
 None
 0.64A 4ac9C-4exqA:
2.7		 4ac9C-4exqA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gzu FERM, RHOGEF AND
PLECKSTRIN
DOMAIN-CONTAINING
PROTEIN 2

(Mus musculus) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 SER A 796
GLY A 794
THR A 788
PHE A 798
 None
 1.05A 4ac9C-4gzuA:
undetectable		 4ac9C-4gzuA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jrb GREEN FLUORESCENT
PROTEIN

(Aequorea
victoria;
Blattella
germanica) 		PF01353
(GFP)
PF06757
(Ins_allergen_rp) 		4 ASP A  19
THR A 108
SER A  28
PHE A  27
 None
 1.04A 4ac9C-4jrbA:
undetectable		 4ac9C-4jrbA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nsd CALCIUM UPTAKE
PROTEIN 1,
MITOCHONDRIAL

(Homo sapiens) 		PF13202
(EF-hand_5)
PF13833
(EF-hand_8) 		4 ASP A 208
THR A 214
SER A 205
PHE A 206
 None
 1.04A 4ac9C-4nsdA:
undetectable		 4ac9C-4nsdA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pdh TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Polaromonas sp.
JS666) 		PF03480
(DctP) 		4 GLY A 273
THR A 274
SER A  48
THR A  44
 None
None
None
EAX  A 401 ( 4.5A)
 0.75A 4ac9C-4pdhA:
undetectable		 4ac9C-4pdhA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tlv ADP-RIBOSYLATING
TOXIN CARDS

(Mycoplasma
pneumoniae) 		PF02917
(Pertussis_S1) 		4 ASP A  99
GLY A  94
SER A 529
PHE A 528
 None
None
None
ACT  A 608 (-4.6A)
 1.00A 4ac9C-4tlvA:
undetectable		 4ac9C-4tlvA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4txg CHITINASE

(Chromobacterium
violaceum) 		PF00704
(Glyco_hydro_18)
PF06483
(ChiC) 		4 ASP A 224
GLY A 231
THR A 211
SER A 226
 None
 1.05A 4ac9C-4txgA:
2.7		 4ac9C-4txgA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wmo XEEL PROTEIN

(Xenopus laevis) 		no annotation 4 GLY F 106
THR F 103
THR F  97
PHE F  98
 None
 1.00A 4ac9C-4wmoF:
undetectable		 4ac9C-4wmoF:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wsh UROPORPHYRINOGEN
DECARBOXYLASE

(Pseudomonas
aeruginosa) 		PF01208
(URO-D) 		4 ASP A 209
GLY A 269
SER A 148
THR A 151
 None
 0.68A 4ac9C-4wshA:
2.8		 4ac9C-4wshA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xbi CLPB PROTEIN,
PUTATIVE,GREEN
FLUORESCENT PROTEIN

(Plasmodium
falciparum;
Aequorea
victoria) 		PF01353
(GFP)
PF02861
(Clp_N) 		4 ASP A 168
THR A 257
SER A 177
PHE A 176
 None
 1.05A 4ac9C-4xbiA:
undetectable		 4ac9C-4xbiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zr8 UROPORPHYRINOGEN
DECARBOXYLASE

(Acinetobacter
baumannii) 		PF01208
(URO-D) 		4 ASP A 208
GLY A 268
SER A 147
THR A 150
 None
 0.72A 4ac9C-4zr8A:
2.8		 4ac9C-4zr8A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a0t RIBONUCLEASE J

(Streptomyces
coelicolor) 		PF00753
(Lactamase_B)
PF07521
(RMMBL) 		4 ASP A 155
THR A 186
SER A 108
THR A 111
 None
 0.77A 4ac9C-5a0tA:
2.3		 4ac9C-5a0tA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aw4 NA, K-ATPASE ALPHA
SUBUNIT

(Squalus
acanthias) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF13246
(Cation_ATPase) 		4 ASP A 882
GLY A 885
SER A 901
PHE A 878
 None
 1.04A 4ac9C-5aw4A:
2.3		 4ac9C-5aw4A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c6g AGR133CP

(Eremothecium
gossypii) 		PF10345
(Cohesin_load) 		4 SER A 591
ASP A 592
GLY A 586
THR A 587
 None
 0.98A 4ac9C-5c6gA:
undetectable		 4ac9C-5c6gA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewq AMIDASE

(Bacillus
anthracis) 		PF01425
(Amidase) 		4 SER A 227
GLY A 250
THR A 249
SER A 192
 None
 0.70A 4ac9C-5ewqA:
undetectable		 4ac9C-5ewqA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fcr COMPLEMENT FACTOR D

(Mus musculus) 		PF00089
(Trypsin) 		4 ASP A 194
GLY A  44
THR A  45
THR A 190
 None
 0.74A 4ac9C-5fcrA:
2.3		 4ac9C-5fcrA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 SER A  50
GLY A  53
THR A  54
THR A 107
 None
 0.74A 4ac9C-5hqlA:
2.4		 4ac9C-5hqlA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iq9 10E8V4 HEAVY CHAIN
GP41 MPER PEPTIDE

(Homo sapiens;
Human
immunodeficiency
virus 1) 		PF07654
(C1-set)
PF07686
(V-set)
PF00517
(GP41) 		4 GLY A  96
THR A  95
THR C 676
PHE C 673
 None
 0.88A 4ac9C-5iq9A:
undetectable		 4ac9C-5iq9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j3n GREEN FLUORESCENT
PROTEIN,HSDR

(Escherichia
coli;
Aequorea
victoria) 		PF01353
(GFP)
PF12008
(EcoR124_C) 		4 ASP A  25
THR A 114
SER A  34
PHE A  33
 None
 1.04A 4ac9C-5j3nA:
undetectable		 4ac9C-5j3nA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j7u MAJOR CAPSID PROTEIN

(Faustovirus) 		PF04451
(Capsid_NCLDV) 		4 SER A 381
GLY A 384
SER A 380
THR A 171
 None
 0.97A 4ac9C-5j7uA:
undetectable		 4ac9C-5j7uA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE

(Aspergillus
flavus) 		PF00743
(FMO-like) 		4 GLY A 192
THR A 191
SER A 501
THR A 499
 SO4  A 602 (-3.3A)
TAM  A 603 (-3.1A)
None
None
 0.98A 4ac9C-5j7xA:
undetectable		 4ac9C-5j7xA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE ALPHA
SUBUNIT

(Aromatoleum
aromaticum) 		PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		4 SER b  69
ASP b   7
GLY b 229
THR b  13
 None
 1.03A 4ac9C-5l9wb:
3.0		 4ac9C-5l9wb:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mse GREEN FLUORESCENT
PROTEIN

(Aequorea
victoria) 		no annotation 4 ASP A  19
THR A 108
SER A  28
PHE A  27
 None
 1.03A 4ac9C-5mseA:
undetectable		 4ac9C-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n2p TRYPTOPHAN SYNTHASE
ALPHA CHAIN

(Sulfolobus
solfataricus) 		no annotation 4 SER A 193
ASP A 197
GLY A 189
SER A 194
 None
 0.87A 4ac9C-5n2pA:
3.8		 4ac9C-5n2pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nvm EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4E
TYPE 2

(Homo sapiens) 		PF01652
(IF4E) 		4 ASP A 112
GLY A 109
THR A 108
PHE A 113
 None
 0.86A 4ac9C-5nvmA:
undetectable		 4ac9C-5nvmA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o77 OMPK35

(Klebsiella
pneumoniae) 		no annotation 4 SER A  31
ASP A  32
THR A  25
THR A  34
 None
 0.96A 4ac9C-5o77A:
undetectable		 4ac9C-5o77A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ol2 ACYL-COA
DEHYDROGENASE

(Clostridioides
difficile) 		no annotation 4 SER C 134
GLY C 130
THR C 131
PHE C 231
 COS  C 402 (-3.2A)
FAD  C 401 (-3.3A)
FAD  C 401 ( 3.2A)
COS  C 402 (-4.6A)
 0.95A 4ac9C-5ol2C:
undetectable		 4ac9C-5ol2C:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opj RHAMNOGALACTURONAN
LYASE

(Bacteroides
thetaiotaomicron) 		no annotation 4 ASP A 227
GLY A 174
THR A 171
PHE A 225
 None
 0.77A 4ac9C-5opjA:
2.3		 4ac9C-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans) 		PF00171
(Aldedh) 		4 ASP A 522
GLY A 525
THR A 526
SER A 521
 None
 1.04A 4ac9C-5ujuA:
3.2		 4ac9C-5ujuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6s ACETYLXYLAN ESTERASE
A

(Aspergillus
awamori) 		PF10503
(Esterase_phd) 		4 SER A 110
ASP A 109
THR A 102
SER A 111
 NA  A 305 ( 4.8A)
None
None
None
 1.00A 4ac9C-5x6sA:
3.3		 4ac9C-5x6sA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b7t GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria) 		no annotation 4 ASP A  49
THR A 138
SER A  58
PHE A  57
 None
 1.01A 4ac9C-6b7tA:
undetectable		 4ac9C-6b7tA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY

(Paraburkholderia
phymatum) 		no annotation 4 ASP A  83
GLY A  88
THR A  87
SER A  34
 None
 0.99A 4ac9C-6c0dA:
3.6		 4ac9C-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4g ASPARTIC PROTEASE
PM5

(Plasmodium
vivax) 		no annotation 4 GLY A 293
THR A 404
THR A 319
PHE A 444
 None
 1.02A 4ac9C-6c4gA:
undetectable		 4ac9C-6c4gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1

(Saccharomyces
cerevisiae) 		no annotation 4 SER A 543
GLY A1253
SER A 549
THR A 943
 None
 1.03A 4ac9C-6eojA:
undetectable		 4ac9C-6eojA:
18.56