SIMILAR PATTERNS OF AMINO ACIDS FOR 4A9K_B_TYLB2198_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dce PROTEIN (RAB
GERANYLGERANYLTRANSF
ERASE ALPHA SUBUNIT)

(Rattus
norvegicus) 		PF01239
(PPTA)
PF07711
(RabGGT_insert) 		4 VAL A 501
LEU A 529
ILE A 526
ASN A 543
 None
 0.97A 4a9kB-1dceA:
3.2		 4a9kB-1dceA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i7n SYNAPSIN II

(Rattus
norvegicus) 		PF02078
(Synapsin)
PF02750
(Synapsin_C) 		4 VAL A 203
LEU A 217
ILE A 220
VAL A 120
 None
 0.95A 4a9kB-1i7nA:
undetectable		 4a9kB-1i7nA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		4 VAL A 113
LEU A 693
ILE A 696
VAL A 135
 None
 0.89A 4a9kB-1jx2A:
undetectable		 4a9kB-1jx2A:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p1v SUPEROXIDE DISMUTASE
[CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 VAL A  47
LEU A 117
ILE A 149
VAL A  29
 None
 0.91A 4a9kB-1p1vA:
undetectable		 4a9kB-1p1vA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tcd TRIOSEPHOSPHATE
ISOMERASE

(Trypanosoma
cruzi) 		PF00121
(TIM) 		4 VAL A 195
LEU A 199
ILE A 203
VAL A 163
 None
 0.95A 4a9kB-1tcdA:
undetectable		 4a9kB-1tcdA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tq5 PROTEIN YHHW

(Escherichia
coli) 		PF02678
(Pirin) 		4 VAL A 183
LEU A 225
ILE A 185
ASN A 195
 None
 0.98A 4a9kB-1tq5A:
undetectable		 4a9kB-1tq5A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vq7 50S RIBOSOMAL
PROTEIN L30P

(Haloarcula
marismortui) 		PF00327
(Ribosomal_L30) 		4 VAL W   5
LEU W 149
ILE W 146
VAL W  65
 None
 0.96A 4a9kB-1vq7W:
undetectable		 4a9kB-1vq7W:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w5d PENICILLIN-BINDING
PROTEIN

(Bacillus
subtilis) 		PF02113
(Peptidase_S13) 		4 VAL A 118
LEU A  87
ILE A 121
VAL A  76
 None
 0.84A 4a9kB-1w5dA:
undetectable		 4a9kB-1w5dA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bb6 TRANSCOBALAMIN II

(Bos taurus) 		PF01122
(Cobalamin_bind) 		4 VAL A 384
LEU A 342
ILE A 396
VAL A 371
 B12  A   0 (-4.3A)
None
None
None
 0.96A 4a9kB-2bb6A:
undetectable		 4a9kB-2bb6A:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cte VIGILIN

(Homo sapiens) 		PF00013
(KH_1) 		4 VAL A  31
LEU A  42
ILE A  50
VAL A  21
 None
 0.86A 4a9kB-2cteA:
undetectable		 4a9kB-2cteA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dyq AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING
FAMILY B MEMBER 3

(Homo sapiens) 		no annotation 4 VAL A 362
LEU A 376
ILE A 365
VAL A 333
 None
 0.94A 4a9kB-2dyqA:
undetectable		 4a9kB-2dyqA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ffu POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 2

(Homo sapiens) 		PF00535
(Glycos_transf_2)
PF00652
(Ricin_B_lectin) 		4 VAL A 468
LEU A 550
ILE A 508
VAL A 490
 None
 0.95A 4a9kB-2ffuA:
undetectable		 4a9kB-2ffuA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i5k UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE

(Saccharomyces
cerevisiae) 		PF01704
(UDPGP) 		4 VAL A 461
LEU A 457
ILE A 479
VAL A 467
 None
 0.96A 4a9kB-2i5kA:
undetectable		 4a9kB-2i5kA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j42 C2 TOXIN
COMPONENT-II

(Clostridium
botulinum) 		PF03495
(Binary_toxB)
PF07691
(PA14)
PF17475
(Binary_toxB_2)
PF17476
(Binary_toxB_3) 		4 LEU A  46
ILE A 135
ASN A  98
VAL A  90
 None
 0.74A 4a9kB-2j42A:
undetectable		 4a9kB-2j42A:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jep XYLOGLUCANASE

(Paenibacillus
pabuli) 		PF00150
(Cellulase) 		4 VAL A 320
LEU A 223
ILE A 127
ASN A  47
 None
 0.92A 4a9kB-2jepA:
undetectable		 4a9kB-2jepA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oap TYPE II SECRETION
SYSTEM PROTEIN

(Archaeoglobus
fulgidus) 		PF00437
(T2SSE) 		4 VAL 1 342
LEU 1 364
ILE 1 264
VAL 1 383
 None
 0.82A 4a9kB-2oap1:
undetectable		 4a9kB-2oap1:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5r GLUTATHIONE
PEROXIDASE 5

(Populus
trichocarpa x
Populus
deltoides) 		PF00255
(GSHPx) 		4 VAL A  12
LEU A  35
ILE A  37
VAL A  17
 None
 0.97A 4a9kB-2p5rA:
undetectable		 4a9kB-2p5rA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pq6 UDP-GLUCURONOSYL/UDP
-GLUCOSYLTRANSFERASE

(Medicago
truncatula) 		PF00201
(UDPGT) 		4 VAL A 473
LEU A 470
ILE A 255
VAL A 123
 None
 0.94A 4a9kB-2pq6A:
undetectable		 4a9kB-2pq6A:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgg 16S RRNA-PROCESSING
PROTEIN RIMM

(Acinetobacter
calcoaceticus) 		PF01782
(RimM)
PF05239
(PRC) 		4 VAL A  29
LEU A  17
ILE A  89
VAL A  58
 None
 0.97A 4a9kB-2qggA:
undetectable		 4a9kB-2qggA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qhs LIPOYLTRANSFERASE

(Thermus
thermophilus) 		PF03099
(BPL_LplA_LipB) 		4 VAL A 142
LEU A 103
ILE A 106
VAL A  95
 None
 0.94A 4a9kB-2qhsA:
undetectable		 4a9kB-2qhsA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qhu LIPOYLTRANSFERASE

(Thermus
thermophilus) 		PF03099
(BPL_LplA_LipB) 		4 VAL A 142
LEU A 103
ILE A 106
VAL A  95
 None
 0.96A 4a9kB-2qhuA:
undetectable		 4a9kB-2qhuA:
19.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2wp1 BROMODOMAIN
TESTIS-SPECIFIC
PROTEIN

(Mus musculus) 		PF00439
(Bromodomain) 		4 VAL A 298
LEU A 303
ASN A 351
VAL A 357
 None
 0.69A 4a9kB-2wp1A:
17.3		 4a9kB-2wp1A:
34.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xde GAG POLYPROTEIN

(Human
immunodeficiency
virus 1) 		PF00607
(Gag_p24) 		4 VAL A  36
LEU A 138
ILE A 141
VAL A  59
 None
 0.71A 4a9kB-2xdeA:
undetectable		 4a9kB-2xdeA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0q RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 3

(Mus musculus) 		PF00621
(RhoGEF) 		4 VAL A 306
LEU A 274
ILE A 269
VAL A 241
 None
 0.96A 4a9kB-2z0qA:
3.2		 4a9kB-2z0qA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB

(Aquifex
aeolicus) 		PF01312
(Bac_export_2) 		4 VAL B 334
LEU B 312
ILE A 261
VAL B 320
 None
 0.89A 4a9kB-3b1sB:
undetectable		 4a9kB-3b1sB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjn TRANSCRIPTIONAL
REGULATOR, PUTATIVE

(Vibrio cholerae) 		PF01614
(IclR) 		4 VAL A 109
ILE A 210
ASN A  86
VAL A  90
 None
 0.90A 4a9kB-3bjnA:
undetectable		 4a9kB-3bjnA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3brk GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE

(Agrobacterium
tumefaciens) 		PF00483
(NTP_transferase) 		4 VAL X 376
LEU X 409
ILE X 273
VAL X  38
 None
 0.99A 4a9kB-3brkX:
undetectable		 4a9kB-3brkX:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmt PROTEIN RECA

(Escherichia
coli) 		PF00154
(RecA) 		4 VAL A  62
LEU A 223
ILE A  64
VAL A  79
 None
 0.98A 4a9kB-3cmtA:
undetectable		 4a9kB-3cmtA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmt PROTEIN RECA

(Escherichia
coli) 		PF00154
(RecA) 		4 VAL A1062
LEU A1223
ILE A1064
VAL A1079
 None
 0.97A 4a9kB-3cmtA:
undetectable		 4a9kB-3cmtA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmt PROTEIN RECA

(Escherichia
coli) 		PF00154
(RecA) 		4 VAL A2062
LEU A2223
ILE A2064
VAL A2079
 None
 0.98A 4a9kB-3cmtA:
undetectable		 4a9kB-3cmtA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmt PROTEIN RECA

(Escherichia
coli) 		PF00154
(RecA) 		4 VAL A3062
LEU A3223
ILE A3064
VAL A3079
 None
 0.98A 4a9kB-3cmtA:
undetectable		 4a9kB-3cmtA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmt PROTEIN RECA

(Escherichia
coli) 		PF00154
(RecA) 		4 VAL A4062
LEU A4223
ILE A4064
VAL A4079
 None
 0.98A 4a9kB-3cmtA:
undetectable		 4a9kB-3cmtA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3del ARGININE BINDING
PROTEIN

(Chlamydia
trachomatis) 		PF00497
(SBP_bac_3) 		4 VAL B 186
LEU B 126
ILE B 207
VAL B 162
 None
 0.79A 4a9kB-3delB:
undetectable		 4a9kB-3delB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e98 GAF DOMAIN OF
UNKNOWN FUNCTION

(Pseudomonas
aeruginosa) 		PF04340
(DUF484) 		4 VAL A 191
LEU A 148
ILE A 144
VAL A 135
 None
 0.98A 4a9kB-3e98A:
undetectable		 4a9kB-3e98A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f7l COPPER,ZINC
SUPEROXIDE DISMUTASE

(Alvinella
pompejana) 		PF00080
(Sod_Cu) 		4 VAL A  45
LEU A 115
ILE A 147
VAL A  27
 None
 0.95A 4a9kB-3f7lA:
undetectable		 4a9kB-3f7lA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gr8 NADPH DEHYDROGENASE

(Geobacillus
kaustophilus) 		PF00724
(Oxidored_FMN) 		4 VAL A 160
LEU A  14
ILE A  11
VAL A  21
 None
 0.82A 4a9kB-3gr8A:
undetectable		 4a9kB-3gr8A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i0w 8-OXOGUANINE-DNA-GLY
COSYLASE

(Clostridium
acetobutylicum) 		PF00730
(HhH-GPD)
PF07934
(OGG_N) 		4 VAL A  54
LEU A  23
ILE A  26
VAL A  18
 None
EDO  A 295 (-3.9A)
None
None
 0.87A 4a9kB-3i0wA:
undetectable		 4a9kB-3i0wA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ide CAPSID PROTEIN VP2

(Infectious
pancreatic
necrosis virus) 		PF01766
(Birna_VP2) 		4 VAL A 133
LEU A 130
ILE A 350
VAL A  52
 None
 0.97A 4a9kB-3ideA:
undetectable		 4a9kB-3ideA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kwe CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN

(Thermosynechococcus
elongatus) 		PF00132
(Hexapep) 		4 VAL A  38
LEU A  34
ILE A  52
VAL A  44
 None
 0.99A 4a9kB-3kweA:
undetectable		 4a9kB-3kweA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l9y SUPEROXIDE DISMUTASE
[CU-ZN]

(Bombyx mori) 		PF00080
(Sod_Cu) 		4 VAL A  46
LEU A 117
ILE A 149
VAL A  28
 None
 0.88A 4a9kB-3l9yA:
undetectable		 4a9kB-3l9yA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mnd SUPEROXIDE DISMUTASE
[CU-ZN]

(Taenia solium) 		PF00080
(Sod_Cu) 		4 VAL A  44
LEU A 114
ILE A 146
VAL A  26
 None
 0.91A 4a9kB-3mndA:
undetectable		 4a9kB-3mndA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mxu GLYCINE CLEAVAGE
SYSTEM H PROTEIN

(Bartonella
henselae) 		PF01597
(GCV_H) 		4 VAL A  87
LEU A  35
ILE A  38
VAL A  65
 None
 0.98A 4a9kB-3mxuA:
undetectable		 4a9kB-3mxuA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Sinorhizobium
meliloti) 		PF03466
(LysR_substrate) 		4 VAL A  90
LEU A 119
ILE A 117
VAL A 285
 None
 0.95A 4a9kB-3mz1A:
undetectable		 4a9kB-3mz1A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n2x UNCHARACTERIZED
PROTEIN YAGE

(Escherichia
coli) 		PF00701
(DHDPS) 		4 VAL A  21
LEU A  39
ILE A  40
VAL A  48
 None
 0.89A 4a9kB-3n2xA:
undetectable		 4a9kB-3n2xA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3obw PROTEIN PELOTA
HOMOLOG

(Sulfolobus
solfataricus) 		PF03463
(eRF1_1)
PF03465
(eRF1_3) 		4 VAL A 287
LEU A 291
ILE A 302
VAL A 273
 None
 0.91A 4a9kB-3obwA:
undetectable		 4a9kB-3obwA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poc ALPHA-GLUCOSIDASE

(Blautia obeum) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 VAL A 221
LEU A 231
ILE A 301
VAL A 209
 None
 0.93A 4a9kB-3pocA:
undetectable		 4a9kB-3pocA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sf5 UREASE ACCESSORY
PROTEIN UREF

(Helicobacter
pylori) 		PF01730
(UreF) 		4 LEU A 170
ILE A 172
ASN A  39
VAL A  38
 None
None
PEG  A 258 (-3.7A)
PEG  A 258 (-4.6A)
 0.92A 4a9kB-3sf5A:
undetectable		 4a9kB-3sf5A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3skq MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
38

(Saccharomyces
cerevisiae) 		PF07766
(LETM1) 		4 VAL A 398
LEU A 198
ILE A 402
VAL A 253
 None
 0.98A 4a9kB-3skqA:
undetectable		 4a9kB-3skqA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos taurus) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 VAL C1029
LEU C1054
ILE C1056
VAL C1117
 None
 0.99A 4a9kB-3sr6C:
undetectable		 4a9kB-3sr6C:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suk CERATO-PLATANIN-LIKE
PROTEIN

(Moniliophthora
perniciosa) 		PF07249
(Cerato-platanin) 		4 VAL A 107
LEU A  95
ILE A  93
VAL A 128
 None
 0.91A 4a9kB-3sukA:
undetectable		 4a9kB-3sukA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vx8 UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME ATG7

(Arabidopsis
thaliana) 		no annotation 4 VAL D 139
LEU D  93
ILE D  45
VAL D  20
 None
 0.85A 4a9kB-3vx8D:
undetectable		 4a9kB-3vx8D:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wky PROPHENOLOXIDASE B

(Marsupenaeus
japonicus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 VAL A 660
LEU A 446
ILE A 662
VAL A 530
 None
 0.97A 4a9kB-3wkyA:
undetectable		 4a9kB-3wkyA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zja SL3965

(Streptomyces
lividans) 		PF04314
(PCuAC) 		4 VAL A 143
LEU A 159
ILE A  60
VAL A  95
 None
 0.95A 4a9kB-3zjaA:
undetectable		 4a9kB-3zjaA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3w ARCHAEMETZINCIN

(Archaeoglobus
fulgidus) 		PF07998
(Peptidase_M54) 		4 VAL A 111
LEU A  18
ASN A  11
VAL A  10
 None
 0.76A 4a9kB-4a3wA:
undetectable		 4a9kB-4a3wA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c4a PROTEIN ARGININE
N-METHYLTRANSFERASE
7

(Mus musculus) 		PF06325
(PrmA) 		4 VAL A 233
LEU A 230
ILE A 228
VAL A 277
 None
 0.97A 4a9kB-4c4aA:
undetectable		 4a9kB-4c4aA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dg5 PHOSPHOGLYCERATE
KINASE

(Staphylococcus
aureus) 		PF00162
(PGK) 		4 LEU A 387
ILE A 390
ASN A 188
VAL A 187
 None
 0.95A 4a9kB-4dg5A:
undetectable		 4a9kB-4dg5A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecn LEUCINE-RICH REPEAT
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF14660
(DUF4458) 		4 VAL A 186
LEU A 165
ILE A 287
VAL A 246
 None
 0.97A 4a9kB-4ecnA:
undetectable		 4a9kB-4ecnA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fho INTERNALIN C2

(Listeria
monocytogenes) 		PF12354
(Internalin_N)
PF12799
(LRR_4)
PF13516
(LRR_6) 		4 VAL A 157
LEU A 182
ILE A 179
ASN A 196
 None
 0.97A 4a9kB-4fhoA:
undetectable		 4a9kB-4fhoA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gs5 ACYL-COA SYNTHETASE
(AMP-FORMING)/AMP-AC
ID LIGASE II-LIKE
PROTEIN

(Dyadobacter
fermentans) 		PF00501
(AMP-binding) 		4 VAL A  54
LEU A  40
ILE A  87
VAL A  94
 None
 0.92A 4a9kB-4gs5A:
undetectable		 4a9kB-4gs5A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hl4 TBC1 DOMAIN FAMILY
MEMBER 20

(Homo sapiens) 		PF00566
(RabGAP-TBC) 		4 VAL A 258
LEU A 203
ILE A 196
VAL A 212
 None
 0.86A 4a9kB-4hl4A:
undetectable		 4a9kB-4hl4A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Ruegeria sp.
TM1040) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 VAL A 118
LEU A  39
ILE A   4
VAL A  91
 None
 0.81A 4a9kB-4ip4A:
undetectable		 4a9kB-4ip4A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis) 		PF00348
(polyprenyl_synt) 		4 VAL A 138
LEU A 142
ILE A 132
VAL A  63
 None
 0.98A 4a9kB-4kkmA:
undetectable		 4a9kB-4kkmA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l39 4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12

(Arabidopsis
thaliana) 		PF03321
(GH3) 		4 VAL A 286
LEU A 318
ILE A 296
VAL A 211
 None
 0.98A 4a9kB-4l39A:
undetectable		 4a9kB-4l39A:
13.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4n3w CREB-BINDING PROTEIN

(Homo sapiens) 		PF00439
(Bromodomain)
PF06001
(DUF902) 		5 VAL A1115
LEU A1120
ILE A1122
ASN A1168
VAL A1174
 None
 0.54A 4a9kB-4n3wA:
18.0		 4a9kB-4n3wA:
98.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o2x MALTOSE-BINDING
PERIPLASMIC PROTEIN,
ATP-DEPENDENT CLP
PROTEASE ADAPTOR
PROTEIN CLPS
CONTAINING PROTEIN
CHIMERIC CONSTRUCT

(Escherichia
coli;
Plasmodium
falciparum) 		PF02617
(ClpS)
PF13416
(SBP_bac_8) 		4 VAL A 477
LEU A 413
ILE A 455
VAL A 427
 None
 0.95A 4a9kB-4o2xA:
undetectable		 4a9kB-4o2xA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oe7 PROBABLE
2-KETO-3-DEOXY-GALAC
TONATE ALDOLASE YAGE

(Escherichia
coli) 		PF00701
(DHDPS) 		4 VAL A  21
LEU A  39
ILE A  40
VAL A  48
 None
 0.88A 4a9kB-4oe7A:
undetectable		 4a9kB-4oe7A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p9g 2,4'-DIHYDROXYACETOP
HENONE DIOXYGENASE

(Alcaligenes sp.) 		PF07883
(Cupin_2) 		4 VAL A 171
LEU A 174
ILE A  54
VAL A  41
 None
 0.96A 4a9kB-4p9gA:
undetectable		 4a9kB-4p9gA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6t GLYCOSYL HYDROLASE,
FAMILY 18

(Pseudomonas
protegens) 		PF00704
(Glyco_hydro_18) 		4 VAL A 163
LEU A 146
ILE A 179
VAL A 151
 None
 0.86A 4a9kB-4q6tA:
undetectable		 4a9kB-4q6tA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q73 PROLINE
DEHYDROGENASE

(Bradyrhizobium
diazoefficiens) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		4 VAL A 933
LEU A 904
ILE A 907
VAL A 918
 None
 0.83A 4a9kB-4q73A:
undetectable		 4a9kB-4q73A:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u0z ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FICD

(Homo sapiens) 		PF02661
(Fic) 		4 LEU A 247
ILE A 246
ASN A 236
VAL A 231
 None
 0.99A 4a9kB-4u0zA:
undetectable		 4a9kB-4u0zA:
14.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2

(Homo sapiens) 		PF00439
(Bromodomain) 		4 VAL A 376
LEU A 381
ASN A 429
VAL A 435
 73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
73B  A1456 (-4.1A)
 0.61A 4a9kB-4uygA:
18.0		 4a9kB-4uygA:
31.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x8n SET1/ASH2 HISTONE
METHYLTRANSFERASE
COMPLEX SUBUNIT ASH2

(Homo sapiens) 		PF00622
(SPRY) 		4 VAL A 316
LEU A 298
ILE A 300
VAL A 480
 None
 0.96A 4a9kB-4x8nA:
undetectable		 4a9kB-4x8nA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xcr SUPEROXIDE DISMUTASE
[CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 VAL A  47
LEU A  87
ILE A 106
VAL A  29
 None
 0.97A 4a9kB-4xcrA:
undetectable		 4a9kB-4xcrA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgt FRQ-INTERACTING RNA
HELICASE

(Neurospora
crassa) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT)
PF13234
(rRNA_proc-arch) 		4 VAL A 555
LEU A 566
ILE A 605
ASN A 359
 None
 0.93A 4a9kB-4xgtA:
undetectable		 4a9kB-4xgtA:
8.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo sapiens) 		PF00439
(Bromodomain) 		4 VAL A 380
LEU A 385
ASN A 433
VAL A 439
 4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-2.8A)
4LD  A 501 (-3.5A)
 0.52A 4a9kB-4z93A:
17.8		 4a9kB-4z93A:
36.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5doo PROTEIN LYSINE
METHYLTRANSFERASE 2

(Rickettsia
typhi) 		PF10119
(MethyTransf_Reg)
PF13847
(Methyltransf_31) 		4 VAL A 135
LEU A 139
ILE A 115
VAL A  73
 None
 0.93A 4a9kB-5dooA:
undetectable		 4a9kB-5dooA:
12.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3

(Homo sapiens) 		PF00439
(Bromodomain) 		4 VAL A 338
LEU A 343
ASN A 391
VAL A 397
 None
 0.69A 4a9kB-5hjcA:
18.2		 4a9kB-5hjcA:
37.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxw L-AMINO ACID
DEAMINASE

(Proteus
vulgaris) 		PF01266
(DAO) 		4 VAL A 271
LEU A 468
ILE A 420
VAL A 254
 None
 0.97A 4a9kB-5hxwA:
undetectable		 4a9kB-5hxwA:
12.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5i8g CREB-BINDING PROTEIN

(Homo sapiens) 		PF00439
(Bromodomain)
PF06001
(DUF902) 		5 VAL A1115
LEU A1120
ILE A1122
ASN A1168
VAL A1174
 69E  A1404 (-4.3A)
69E  A1404 (-4.2A)
69E  A1404 ( 4.7A)
69E  A1404 (-3.0A)
69E  A1404 (-4.8A)
 0.39A 4a9kB-5i8gA:
19.1		 4a9kB-5i8gA:
88.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ict GLUTAMATE RECEPTOR 1

(Drosophila
melanogaster) 		PF10613
(Lig_chan-Glu_bd) 		4 VAL A 186
LEU A 195
ASN A 206
VAL A 205
 None
 0.81A 4a9kB-5ictA:
undetectable		 4a9kB-5ictA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5in8 ARISTOLOCHENE
SYNTHASE

(Aspergillus
terreus) 		no annotation 4 VAL A  79
LEU A 125
ILE A 122
VAL A 144
 None
 0.92A 4a9kB-5in8A:
undetectable		 4a9kB-5in8A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j07 SUPEROXIDE DISMUTASE
[CU-ZN],SUPEROXIDE
DISMUTASE
[CU-ZN],SUPEROXIDE
DISMUTASE
[CU-ZN],SUPEROXIDE
DISMUTASE [CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 VAL A  36
LEU A  76
ILE A  95
VAL A  18
 None
 0.94A 4a9kB-5j07A:
undetectable		 4a9kB-5j07A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j0c SUPEROXIDE DISMUTASE
[CU-ZN],SUPEROXIDE
DISMUTASE
[CU-ZN],OXIDOREDUCTA
SE,SUPEROXIDE
DISMUTASE [CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 VAL A  21
LEU A  61
ILE A  80
VAL A   3
 None
 0.92A 4a9kB-5j0cA:
undetectable		 4a9kB-5j0cA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j0f SUPEROXIDE DISMUTASE
[CU-ZN],OXIDOREDUCTA
SE,SUPEROXIDE
DISMUTASE [CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 VAL A 111
LEU A  37
ILE A  56
VAL A  93
 None
 0.91A 4a9kB-5j0fA:
undetectable		 4a9kB-5j0fA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j0g OXIDOREDUCTASE,SUPER
OXIDE DISMUTASE
[CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 VAL A  65
LEU A 105
ILE A  10
VAL A  47
 None
 0.94A 4a9kB-5j0gA:
undetectable		 4a9kB-5j0gA:
15.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5lpk HISTONE
ACETYLTRANSFERASE
P300

(Homo sapiens) 		PF00439
(Bromodomain) 		5 VAL A1079
LEU A1084
ILE A1086
ASN A1132
VAL A1138
 XDM  A1201 (-4.7A)
XDM  A1201 ( 4.4A)
None
XDM  A1201 (-3.1A)
None
 0.49A 4a9kB-5lpkA:
22.1		 4a9kB-5lpkA:
91.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lts RNA-DIRECTED RNA
POLYMERASE L

(Lymphocytic
choriomeningitis
mammarenavirus) 		PF17296
(ArenaCapSnatch) 		4 VAL A  68
LEU A  82
ILE A 125
VAL A 134
 None
 0.82A 4a9kB-5ltsA:
undetectable		 4a9kB-5ltsA:
23.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1

(Candida
albicans) 		PF00439
(Bromodomain) 		4 VAL A 415
ILE A 422
ASN A 468
VAL A 474
 GOL  A 502 ( 4.0A)
None
GOL  A 501 (-3.1A)
None
 0.63A 4a9kB-5n13A:
17.1		 4a9kB-5n13A:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5twb FERREDOXIN--NADP
REDUCTASE

(Staphylococcus
aureus) 		PF07992
(Pyr_redox_2) 		4 VAL A  83
LEU A 251
ILE A 113
VAL A 109
 FAD  A 401 (-3.9A)
FAD  A 401 ( 3.9A)
FAD  A 401 (-3.6A)
None
 0.82A 4a9kB-5twbA:
undetectable		 4a9kB-5twbA:
14.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5u6v BROMODOMAIN-CONTAINI
NG PROTEIN 2

(Homo sapiens) 		no annotation 4 VAL A 376
LEU A 381
ASN A 429
VAL A 435
 7WY  A 501 ( 4.5A)
7WY  A 501 (-4.9A)
7WY  A 501 (-3.4A)
7WY  A 501 (-4.1A)
 0.46A 4a9kB-5u6vA:
18.1		 4a9kB-5u6vA:
36.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5u7g CREB-BINDING PROTEIN

(Mus musculus) 		PF00439
(Bromodomain)
PF00569
(ZZ)
PF06001
(DUF902)
PF08214
(HAT_KAT11) 		5 VAL A1116
LEU A1121
ILE A1123
ASN A1169
VAL A1175
 None
 0.75A 4a9kB-5u7gA:
20.3		 4a9kB-5u7gA:
94.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u81 ACID CERAMIDASE
ISOFORM B

(Heterocephalus
glaber) 		no annotation 4 VAL A 363
LEU A 358
ILE A 357
VAL A 317
 None
 0.99A 4a9kB-5u81A:
undetectable		 4a9kB-5u81A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uwy THIOREDOXIN
REDUCTASE

(Streptococcus
pyogenes) 		PF07992
(Pyr_redox_2) 		4 VAL A 243
LEU A 246
ILE A 248
VAL A 103
 None
 0.87A 4a9kB-5uwyA:
undetectable		 4a9kB-5uwyA:
15.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5w0e CREB-BINDING PROTEIN

(Homo sapiens) 		no annotation 5 VAL A1115
LEU A1120
ILE A1122
ASN A1168
VAL A1174
 9U4  A1201 (-4.6A)
9U4  A1201 ( 4.1A)
9U4  A1201 (-4.3A)
9U4  A1201 (-3.2A)
9U4  A1201 (-4.7A)
 0.38A 4a9kB-5w0eA:
22.8		 4a9kB-5w0eA:
75.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3t RANBP-TYPE AND
C3HC4-TYPE ZINC
FINGER-CONTAINING
PROTEIN 1

(Mus musculus) 		no annotation 4 VAL A  75
LEU A 114
ILE A 119
VAL A  59
 None
 0.98A 4a9kB-5y3tA:
undetectable		 4a9kB-5y3tA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b9s METHYLPHOSPHONATE
SYNTHASE

(Nitrosopumilus
maritimus) 		no annotation 4 VAL A 369
LEU A 392
ILE A 379
VAL A 351
 None
 0.96A 4a9kB-6b9sA:
undetectable		 4a9kB-6b9sA:
23.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6cw0 CGD2_2690 PROTEIN

(Cryptosporidium
parvum) 		no annotation 4 VAL A  30
LEU A  35
ASN A  83
VAL A  89
 R78  A 201 (-4.5A)
R78  A 201 (-4.9A)
R78  A 201 (-3.3A)
UNX  A 205 ( 4.1A)
 0.53A 4a9kB-6cw0A:
18.1		 4a9kB-6cw0A:
38.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6er3 BNR/ASP-BOX REPEAT
PROTEIN

([Ruminococcus]
gnavus) 		no annotation 4 VAL A  82
LEU A 129
ILE A 136
ASN A 132
 None
 0.99A 4a9kB-6er3A:
undetectable		 4a9kB-6er3A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gdr -

(-) 		no annotation 4 VAL A  31
LEU A 169
ILE A  26
VAL A 210
 None
 0.98A 4a9kB-6gdrA:
undetectable		 4a9kB-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculosis) 		no annotation 4 VAL A 352
LEU A 329
ILE A 309
VAL A 303
 VAL  A 352 ( 0.6A)
LEU  A 329 ( 0.6A)
ILE  A 309 ( 0.7A)
VAL  A 303 ( 0.6A)
 0.98A 4a9kB-6gefA:
undetectable		 4a9kB-6gefA:
22.02