SIMILAR PATTERNS OF AMINO ACIDS FOR 4A99_D_MIYD393

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cby DELTA-ENDOTOXIN CYTB

(Bacillus
thuringiensis) 		PF01338
(Bac_thur_toxin) 		4 ILE A 107
ILE A 101
TYR A 213
GLU A 214
 None
 1.18A 4a99D-1cbyA:
undetectable		 4a99D-1cbyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d5y ROB TRANSCRIPTION
FACTOR

(Escherichia
coli) 		PF06445
(GyrI-like)
PF12833
(HTH_18) 		4 ILE A 261
ILE A 287
TYR A 224
GLU A 223
 None
 1.23A 4a99D-1d5yA:
undetectable		 4a99D-1d5yA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dbh PROTEIN (HUMAN SOS
1)

(Homo sapiens) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 ILE A 252
ILE A 212
TYR A 215
GLU A 211
 None
 1.03A 4a99D-1dbhA:
undetectable		 4a99D-1dbhA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e4o MALTODEXTRIN
PHOSPHORYLASE

(Escherichia
coli) 		PF00343
(Phosphorylase) 		4 ILE A 791
GLN A 304
ILE A 303
GLU A 301
 None
 1.08A 4a99D-1e4oA:
undetectable		 4a99D-1e4oA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ee1 NH(3)-DEPENDENT
NAD(+) SYNTHETASE

(Bacillus
subtilis) 		PF02540
(NAD_synthase) 		4 ILE A   6
ILE A 231
TYR A 234
GLU A 230
 None
 1.09A 4a99D-1ee1A:
1.9		 4a99D-1ee1A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g5b SERINE/THREONINE
PROTEIN PHOSPHATASE

(Escherichia
virus Lambda) 		PF00149
(Metallophos) 		4 ILE A 125
ILE A 176
TYR A 147
GLU A 146
 None
 1.14A 4a99D-1g5bA:
undetectable		 4a99D-1g5bA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gjj LAP2

(Homo sapiens) 		PF03020
(LEM)
PF08198
(Thymopoietin) 		4 GLN A  32
ILE A 134
TYR A 142
GLU A 143
 None
 1.23A 4a99D-1gjjA:
undetectable		 4a99D-1gjjA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1la2 MYO-INOSITOL-1-PHOSP
HATE SYNTHASE

(Saccharomyces
cerevisiae) 		PF01658
(Inos-1-P_synth)
PF07994
(NAD_binding_5) 		4 ILE A 185
ILE A 275
TYR A 187
GLU A 273
 None
 1.06A 4a99D-1la2A:
3.2		 4a99D-1la2A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n31 L-CYSTEINE/CYSTINE
LYASE C-DES

(Synechocystis
sp. PCC 6714) 		PF00266
(Aminotran_5) 		4 ILE A 118
ILE A 107
TYR A 132
GLU A 106
 None
 1.19A 4a99D-1n31A:
undetectable		 4a99D-1n31A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1obg PHOSPHORIBOSYLAMIDOI
MIDAZOLE-
SUCCINOCARBOXAMIDE
SYNTHASE

(Saccharomyces
cerevisiae) 		PF01259
(SAICAR_synt) 		4 ILE A  50
ILE A 293
TYR A 292
GLU A 294
 None
None
MG  A 310 (-4.4A)
None
 1.27A 4a99D-1obgA:
undetectable		 4a99D-1obgA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q2l PROTEASE III

(Escherichia
coli) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF16187
(Peptidase_M16_M) 		4 ILE A  47
GLN A  45
ILE A  34
GLU A 425
 None
 1.25A 4a99D-1q2lA:
1.2		 4a99D-1q2lA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sbq 5,10-METHENYLTETRAHY
DROFOLATE SYNTHETASE
HOMOLOG

(Mycoplasma
pneumoniae) 		PF01812
(5-FTHF_cyc-lig) 		4 ILE A  99
ILE A  84
TYR A 126
GLU A  83
 None
 1.23A 4a99D-1sbqA:
undetectable		 4a99D-1sbqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sbq 5,10-METHENYLTETRAHY
DROFOLATE SYNTHETASE
HOMOLOG

(Mycoplasma
pneumoniae) 		PF01812
(5-FTHF_cyc-lig) 		4 ILE A  99
ILE A  85
TYR A 126
GLU A  83
 None
 1.18A 4a99D-1sbqA:
undetectable		 4a99D-1sbqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sdo BSTYI

(Geobacillus
stearothermophilus) 		PF09195
(Endonuc-BglII) 		4 GLN A 100
ILE A 104
TYR A  81
GLU A 110
 None
 1.22A 4a99D-1sdoA:
undetectable		 4a99D-1sdoA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t5i C_TERMINAL DOMAIN OF
A PROBABLE
ATP-DEPENDENT RNA
HELICASE

(Homo sapiens) 		PF00271
(Helicase_C) 		4 ILE A 411
ILE A 399
TYR A 371
GLU A 366
 None
 1.22A 4a99D-1t5iA:
undetectable		 4a99D-1t5iA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t98 CHROMOSOME PARTITION
PROTEIN MUKF

(Escherichia
coli) 		PF03882
(KicB)
PF17192
(MukF_M) 		4 ILE A 171
GLN A 128
ILE A 131
GLU A 135
 None
 1.21A 4a99D-1t98A:
undetectable		 4a99D-1t98A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tu2 APOCYTOCHROME F

(Nostoc sp. PCC
7119) 		PF01333
(Apocytochr_F_C)
PF16639
(Apocytochr_F_N) 		4 ILE B 142
ILE B 247
TYR B 147
GLU B 246
 None
 1.14A 4a99D-1tu2B:
undetectable		 4a99D-1tu2B:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdv SON OF SEVENLESS
PROTEIN HOMOLOG 1

(Homo sapiens) 		PF00169
(PH)
PF00617
(RasGEF)
PF00618
(RasGEF_N)
PF00621
(RhoGEF) 		4 ILE A 252
ILE A 212
TYR A 215
GLU A 211
 None
 1.02A 4a99D-1xdvA:
undetectable		 4a99D-1xdvA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3

(Clostridium
botulinum) 		PF03496
(ADPrib_exo_Tox) 		4 ILE B1086
GLN B1107
ILE B1076
TYR B1079
 None
 1.27A 4a99D-2bovB:
undetectable		 4a99D-2bovB:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bs9 BETA-XYLOSIDASE

(Geobacillus
stearothermophilus) 		PF01229
(Glyco_hydro_39) 		4 ILE A 302
ILE A 276
TYR A 279
GLU A 278
 None
 0.87A 4a99D-2bs9A:
undetectable		 4a99D-2bs9A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i0s AROMATIC AMINE
DEHYDROGENASE

(Alcaligenes
faecalis) 		PF06433
(Me-amine-dh_H) 		4 ILE A 194
GLN A 128
ILE A 136
GLU A 166
 None
 1.22A 4a99D-2i0sA:
undetectable		 4a99D-2i0sA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i4c BICARBONATE
TRANSPORTER

(Synechocystis
sp. PCC 6803) 		PF13379
(NMT1_2) 		4 ILE A 115
GLN A  96
ILE A  66
GLU A 271
 None
None
None
BCT  A 460 ( 2.9A)
 1.15A 4a99D-2i4cA:
undetectable		 4a99D-2i4cA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6l ALDEHYDE
DEHYDROGENASE FAMILY
7 MEMBER A1

(Homo sapiens) 		PF00171
(Aldedh) 		4 ILE A  90
ILE A 126
TYR A 123
GLU A 122
 None
 1.21A 4a99D-2j6lA:
1.6		 4a99D-2j6lA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jlm PUTATIVE
PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE

(Acinetobacter
baylyi) 		PF13420
(Acetyltransf_4) 		4 ILE A 139
GLN A 143
ILE A 148
TYR A 169
 None
 1.25A 4a99D-2jlmA:
undetectable		 4a99D-2jlmA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jyn UPF0368 PROTEIN
YPL225W

(Saccharomyces
cerevisiae) 		PF04669
(Polysacc_synt_4) 		4 ILE A  96
ILE A 131
TYR A 127
GLU A 130
 None
 1.21A 4a99D-2jynA:
undetectable		 4a99D-2jynA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jz5 UNCHARACTERIZED
PROTEIN VPA0419

(Vibrio
parahaemolyticus) 		PF04175
(DUF406) 		4 ILE A  19
ILE A  35
TYR A  34
GLU A  36
 None
 1.04A 4a99D-2jz5A:
undetectable		 4a99D-2jz5A:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kwa KINASE A INHIBITOR

(Bacillus
subtilis) 		PF02682
(CT_C_D) 		4 ILE A  93
ILE A  40
TYR A  39
GLU A  41
 None
 0.81A 4a99D-2kwaA:
undetectable		 4a99D-2kwaA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ljk PROTEIN C17ORF37

(Homo sapiens) 		PF10262
(Rdx) 		4 ILE A  92
ILE A  55
TYR A  52
GLU A  20
 None
 1.18A 4a99D-2ljkA:
undetectable		 4a99D-2ljkA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lol ACYL CARRIER PROTEIN

(Rickettsia
prowazekii) 		PF00550
(PP-binding) 		4 ILE A   7
ILE A  56
TYR A  54
GLU A  51
 None
 1.10A 4a99D-2lolA:
undetectable		 4a99D-2lolA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p9j HYPOTHETICAL PROTEIN
AQ2171

(Aquifex
aeolicus) 		PF08282
(Hydrolase_3) 		4 ILE A 103
ILE A  88
TYR A  89
GLU A  87
 None
 1.20A 4a99D-2p9jA:
undetectable		 4a99D-2p9jA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pa6 ENOLASE

(Methanocaldococcus
jannaschii) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 ILE A  99
ILE A  11
TYR A  88
GLU A  10
 None
 0.98A 4a99D-2pa6A:
undetectable		 4a99D-2pa6A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uuu ALKYLDIHYDROXYACETON
EPHOSPHATE SYNTHASE

(Dictyostelium
discoideum) 		PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C) 		4 ILE A 130
ILE A 525
TYR A 524
GLU A 526
 None
 1.14A 4a99D-2uuuA:
2.1		 4a99D-2uuuA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xal INOSITOL-PENTAKISPHO
SPHATE 2-KINASE

(Arabidopsis
thaliana) 		PF06090
(Ins_P5_2-kin) 		4 ILE A 315
ILE A 356
TYR A 360
GLU A 359
 None
 1.08A 4a99D-2xalA:
undetectable		 4a99D-2xalA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xde GAG POLYPROTEIN

(Human
immunodeficiency
virus 1) 		PF00607
(Gag_p24) 		4 ILE A  73
ILE A 129
TYR A 130
GLU A 128
 1B0  A1148 ( 4.1A)
None
None
None
 1.12A 4a99D-2xdeA:
undetectable		 4a99D-2xdeA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yhe SEC-ALKYL SULFATASE

(Pseudomonas sp.
DSM 6611) 		PF00753
(Lactamase_B)
PF14863
(Alkyl_sulf_dimr)
PF14864
(Alkyl_sulf_C) 		4 ILE A 352
GLN A 126
ILE A 137
GLU A 139
 None
 0.78A 4a99D-2yheA:
undetectable		 4a99D-2yheA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ypd PROBABLE JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION PROT
EIN 2C

(Homo sapiens) 		PF02373
(JmjC) 		4 ILE A2458
GLN A2452
ILE A2451
GLU A2370
 None
 1.09A 4a99D-2ypdA:
undetectable		 4a99D-2ypdA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z61 PROBABLE ASPARTATE
AMINOTRANSFERASE 2

(Methanocaldococcus
jannaschii) 		PF00155
(Aminotran_1_2) 		4 ILE A  68
GLN A 260
ILE A 258
TYR A 261
 None
 1.13A 4a99D-2z61A:
undetectable		 4a99D-2z61A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zc0 ALANINE GLYOXYLATE
TRANSAMINASE

(Thermococcus
litoralis) 		PF00155
(Aminotran_1_2) 		4 ILE A  77
GLN A 284
ILE A 282
TYR A 285
 None
 1.03A 4a99D-2zc0A:
undetectable		 4a99D-2zc0A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3auf GLYCINAMIDE
RIBONUCLEOTIDE
TRANSFORMYLASE 1

(Symbiobacterium
toebii) 		PF00551
(Formyl_trans_N) 		4 ILE A 149
GLN A 152
ILE A 177
GLU A 180
 None
 1.02A 4a99D-3aufA:
4.3		 4a99D-3aufA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3brx ANNEXIN

(Gossypium
hirsutum) 		PF00191
(Annexin) 		4 ILE A 259
ILE A 284
TYR A 288
GLU A 287
 None
None
None
PO4  A 322 ( 4.8A)
 1.26A 4a99D-3brxA:
undetectable		 4a99D-3brxA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d36 SPORULATION KINASE B

(Geobacillus
stearothermophilus) 		PF00512
(HisKA)
PF02518
(HATPase_c) 		4 ILE A 398
ILE A 389
TYR A 386
GLU A 390
 None
 1.15A 4a99D-3d36A:
undetectable		 4a99D-3d36A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fca CYSTEINE SYNTHASE

(Thermus
thermophilus) 		PF00291
(PALP) 		4 ILE A 290
GLN A 210
ILE A 209
TYR A 238
 None
 1.08A 4a99D-3fcaA:
2.1		 4a99D-3fcaA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3foa TAIL SHEATH PROTEIN
GP18

(Escherichia
virus T4) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N) 		4 ILE A 143
ILE A  99
TYR A 101
GLU A 100
 None
 1.24A 4a99D-3foaA:
2.7		 4a99D-3foaA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5l PUTATIVE
BRANCHED-CHAIN AMINO
ACID ABC TRANSPORTER

(Ruegeria
pomeroyi) 		PF13458
(Peripla_BP_6) 		4 ILE A 107
GLN A 104
ILE A 100
GLU A 122
 None
 1.01A 4a99D-3h5lA:
2.4		 4a99D-3h5lA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjb GLUCOSE-6-PHOSPHATE
ISOMERASE

(Vibrio cholerae) 		PF00342
(PGI) 		4 ILE A 336
ILE A 494
TYR A 490
GLU A 491
 None
 1.23A 4a99D-3hjbA:
undetectable		 4a99D-3hjbA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ive NUCLEOTIDASE

(Escherichia
coli) 		PF00149
(Metallophos)
PF02872
(5_nucleotid_C) 		4 ILE A 453
ILE A 461
TYR A 459
GLU A 402
 None
 1.13A 4a99D-3iveA:
undetectable		 4a99D-3iveA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j2n TAIL SHEATH PROTEIN
GP18

(Escherichia
virus T4) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N)
PF17482
(Phage_sheath_1C) 		4 ILE U 143
ILE U  99
TYR U 101
GLU U 100
 None
 1.24A 4a99D-3j2nU:
undetectable		 4a99D-3j2nU:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)

(Helicobacter
pylori) 		PF00483
(NTP_transferase) 		4 ILE A  30
ILE A 134
TYR A  38
GLU A  42
 None
 1.13A 4a99D-3jujA:
undetectable		 4a99D-3jujA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9y 1,25-DIHYDROXYVITAMI
N D(3)
24-HYDROXYLASE,
MITOCHONDRIAL

(Rattus
norvegicus) 		PF00067
(p450) 		4 ILE A 179
GLN A 471
ILE A 172
GLU A 171
 None
 1.26A 4a99D-3k9yA:
undetectable		 4a99D-3k9yA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kny HYPOTHETICAL PROTEIN
BT_3535

(Bacteroides
thetaiotaomicron) 		no annotation 4 ILE A  95
ILE A  71
TYR A  69
GLU A  70
 None
 1.18A 4a99D-3knyA:
undetectable		 4a99D-3knyA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT

(Acetoanaerobium
sticklandii) 		PF02310
(B12-binding)
PF09043
(Lys-AminoMut_A)
PF16554
(OAM_dimer) 		4 ILE A 726
ILE A 633
TYR A 636
GLU A 634
 None
 1.25A 4a99D-3koyA:
undetectable		 4a99D-3koyA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kx2 PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE PRP43

(Saccharomyces
cerevisiae) 		no annotation 4 ILE B  19
GLN B  22
ILE B  26
GLU B 633
 None
 1.01A 4a99D-3kx2B:
undetectable		 4a99D-3kx2B:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mf9 ENDO-1,4-BETA-XYLANA
SE

(Thermopolyspora
flexuosa) 		PF00457
(Glyco_hydro_11) 		4 ILE A 152
GLN A 172
ILE A 173
GLU A 177
 None
 0.99A 4a99D-3mf9A:
undetectable		 4a99D-3mf9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		4 ILE A 874
ILE A 940
TYR A 737
GLU A 736
 None
 1.24A 4a99D-3opyA:
4.2		 4a99D-3opyA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oqn CATABOLITE CONTROL
PROTEIN A

(Bacillus
subtilis) 		PF00356
(LacI)
PF13377
(Peripla_BP_3) 		4 ILE A 181
ILE A 166
TYR A 201
GLU A 163
 None
 1.26A 4a99D-3oqnA:
4.3		 4a99D-3oqnA:
21.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		5 ILE A 333
GLN A 356
ILE A 359
TYR A 360
GLU A 363
 None
 0.37A 4a99D-3p9uA:
58.1		 4a99D-3p9uA:
94.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qki GLUCOSE-6-PHOSPHATE
ISOMERASE

(Plasmodium
falciparum) 		PF00342
(PGI) 		4 ILE A 360
ILE A 519
TYR A 515
GLU A 516
 None
 1.19A 4a99D-3qkiA:
undetectable		 4a99D-3qkiA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Mycobacteroides
abscessus) 		PF01259
(SAICAR_synt) 		4 ILE A  46
ILE A 278
TYR A 277
GLU A 279
 ILE  A  46 ( 0.7A)
ILE  A 278 ( 0.7A)
TYR  A 277 ( 1.3A)
GLU  A 279 ( 0.6A)
 1.23A 4a99D-3r9rA:
undetectable		 4a99D-3r9rA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3trp CALSEQUESTRIN-1

(Oryctolagus
cuniculus) 		PF01216
(Calsequestrin) 		4 ILE A 104
ILE A 174
TYR A 173
GLU A 145
 None
None
None
NA  A 365 ( 4.6A)
 1.03A 4a99D-3trpA:
0.7		 4a99D-3trpA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9w LEUKOTRIENE A-4
HYDROLASE

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C) 		4 ILE A1476
GLN A1473
ILE A1469
GLU A1501
 None
None
None
IMD  A2009 (-2.7A)
 0.98A 4a99D-3u9wA:
undetectable		 4a99D-3u9wA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4

(Rattus
norvegicus) 		PF00058
(Ldl_recept_b)
PF14670
(FXa_inhibition) 		4 ILE B 605
ILE B 579
TYR B 569
GLU B 580
 None
 1.18A 4a99D-3v65B:
undetectable		 4a99D-3v65B:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ak1 BT_4661

(Bacteroides
thetaiotaomicron) 		PF16319
(DUF4958) 		4 ILE A 190
ILE A 221
TYR A 195
GLU A 220
 None
 1.24A 4a99D-4ak1A:
undetectable		 4a99D-4ak1A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvq GLUTAMATE-PYRUVATE
AMINOTRANSFERASE
ALAA

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 ILE A 203
ILE A 265
TYR A 264
GLU A 266
 None
 1.19A 4a99D-4cvqA:
undetectable		 4a99D-4cvqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2

(Neurospora
crassa) 		PF00929
(RNase_T)
PF13423
(UCH_1) 		4 ILE A 718
ILE A 747
TYR A 778
GLU A 746
 None
 1.08A 4a99D-4czwA:
undetectable		 4a99D-4czwA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN

(Rhizobium etli) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 ILE A 351
ILE A 133
TYR A 130
GLU A 327
 None
 1.17A 4a99D-4fb5A:
3.5		 4a99D-4fb5A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4flb REGULATION OF
NUCLEAR PRE-MRNA
DOMAIN-CONTAINING
PROTEIN 2

(Homo sapiens) 		PF04818
(CTD_bind) 		4 ILE A  85
ILE A 138
TYR A 133
GLU A 136
 None
 1.07A 4a99D-4flbA:
undetectable		 4a99D-4flbA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hbr PUTATIVE PERIPLASMIC
PROTEIN

(Bacteroides
eggerthii) 		PF11396
(PepSY_like) 		4 ILE A 147
GLN A 132
ILE A 133
GLU A  97
 None
 1.13A 4a99D-4hbrA:
undetectable		 4a99D-4hbrA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nn7 THYMIC STROMAL
LYMPHOPOIETIN

(Mus musculus) 		PF15216
(TSLP) 		4 ILE A  54
GLN A 127
ILE A 128
TYR A  70
 None
 1.18A 4a99D-4nn7A:
undetectable		 4a99D-4nn7A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4noo VGRG PROTEIN

(Vibrio cholerae) 		no annotation 4 ILE A 950
GLN A 914
ILE A 915
GLU A 926
 None
 1.16A 4a99D-4nooA:
undetectable		 4a99D-4nooA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4npa PUTATIVE
UNCHARACTERIZED
PROTEIN

(Vibrio cholerae) 		PF03641
(Lysine_decarbox)
PF11892
(DUF3412)
PF14793
(DUF4478) 		4 ILE A 357
ILE A 270
TYR A 269
GLU A 266
 None
 1.20A 4a99D-4npaA:
undetectable		 4a99D-4npaA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP

(Salmonella
enterica) 		PF12468
(TTSSLRR)
PF14496
(NEL) 		4 GLN A 219
ILE A 197
TYR A 196
GLU A 152
 None
 1.20A 4a99D-4pufA:
undetectable		 4a99D-4pufA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore) 		4 ILE A 239
ILE A 270
TYR A 254
GLU A 257
 None
 1.21A 4a99D-4r04A:
undetectable		 4a99D-4r04A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rma EZRIN

(Homo sapiens) 		PF00373
(FERM_M)
PF09379
(FERM_N)
PF09380
(FERM_C) 		4 ILE A 110
ILE A 194
TYR A 191
GLU A 190
 None
 1.20A 4a99D-4rmaA:
undetectable		 4a99D-4rmaA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tvv TYROSINE PHOSPHATASE
II SUPERFAMILY
PROTEIN

(Legionella
pneumophila) 		PF14566
(PTPlike_phytase) 		4 ILE A  58
GLN A 263
ILE A 260
GLU A 257
 None
 1.08A 4a99D-4tvvA:
undetectable		 4a99D-4tvvA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzy FLAGELLAR ASSOCIATED
PROTEIN

(Chlamydomonas
reinhardtii) 		PF12895
(ANAPC3)
PF13174
(TPR_6) 		4 ILE A 470
ILE A 500
TYR A 499
GLU A 509
 None
 1.12A 4a99D-4uzyA:
undetectable		 4a99D-4uzyA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xt1 FRACTALKINE

(Homo sapiens) 		PF00048
(IL8) 		4 GLN B  29
ILE B  40
TYR B  27
GLU B  42
 None
 1.20A 4a99D-4xt1B:
undetectable		 4a99D-4xt1B:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y13 TRANSCRIPTIONAL
REGULATOR OF FTSQAZ
GENE CLUSTER

(Escherichia
coli) 		PF00196
(GerE)
PF03472
(Autoind_bind) 		4 ILE A 172
ILE A  30
TYR A  27
GLU A  31
 None
 0.97A 4a99D-4y13A:
undetectable		 4a99D-4y13A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yep LAMININ SUBUNIT
ALPHA-2

(Homo sapiens) 		PF00052
(Laminin_B) 		4 ILE A1286
ILE A1339
TYR A1338
GLU A1242
 EDO  A1405 (-3.9A)
None
EDO  A1405 (-4.6A)
None
 1.25A 4a99D-4yepA:
undetectable		 4a99D-4yepA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zke SUPERKILLER PROTEIN
7

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU) 		4 ILE A 257
GLN A 558
ILE A 557
TYR A 556
 ILE  A 257 ( 0.4A)
GLN  A 558 ( 0.6A)
ILE  A 557 ( 0.4A)
TYR  A 556 ( 1.3A)
 1.25A 4a99D-4zkeA:
undetectable		 4a99D-4zkeA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zmh UNCHARACTERIZED
PROTEIN

(Saccharophagus
degradans) 		PF15979
(Glyco_hydro_115) 		4 ILE A 358
GLN A 374
ILE A 325
GLU A 323
 None
 0.90A 4a99D-4zmhA:
3.8		 4a99D-4zmhA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a49 MATERNAL EFFECT
PROTEIN OSKAR

(Drosophila
melanogaster) 		PF12872
(OST-HTH) 		4 ILE A 156
ILE A 177
TYR A 181
GLU A 180
 None
 1.16A 4a99D-5a49A:
undetectable		 4a99D-5a49A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ail POLY [ADP-RIBOSE]
POLYMERASE 9

(Homo sapiens) 		PF01661
(Macro) 		4 ILE A 286
ILE A 440
TYR A 441
GLU A 439
 None
 1.13A 4a99D-5ailA:
undetectable		 4a99D-5ailA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cd7 MATERNAL EFFECT
PROTEIN OSKAR

(Drosophila
melanogaster) 		PF12872
(OST-HTH) 		4 ILE A 156
ILE A 177
TYR A 181
GLU A 180
 None
None
None
GOL  A 302 (-3.5A)
 1.02A 4a99D-5cd7A:
undetectable		 4a99D-5cd7A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cd8 MATERNAL EFFECT
PROTEIN OSKAR

(Drosophila
melanogaster) 		PF12872
(OST-HTH) 		4 ILE A 156
ILE A 177
TYR A 181
GLU A 180
 None
 1.16A 4a99D-5cd8A:
undetectable		 4a99D-5cd8A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5coa IRIDOID SYNTHASE

(Catharanthus
roseus) 		no annotation 4 GLN A  82
ILE A  81
TYR A  80
GLU A  79
 None
 1.03A 4a99D-5coaA:
5.9		 4a99D-5coaA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9w MRNA CAP GUANINE-N7
METHYLTRANSFERASE

(Homo sapiens) 		PF03291
(Pox_MCEL) 		4 ILE A 466
ILE A 340
TYR A 341
GLU A 363
 None
 1.17A 4a99D-5e9wA:
undetectable		 4a99D-5e9wA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jo7 VETISPIRADIENE
SYNTHASE 1

(Hyoscyamus
muticus) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 ILE A 523
ILE A 453
TYR A 527
GLU A 457
 None
 1.07A 4a99D-5jo7A:
undetectable		 4a99D-5jo7A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE

(Porphyromonas
endodontalis) 		PF10459
(Peptidase_S46) 		4 ILE A 128
GLN A  29
ILE A  31
TYR A  51
 None
 1.23A 4a99D-5jxkA:
undetectable		 4a99D-5jxkA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jzx UDP-N-ACETYLENOLPYRU
VOYLGLUCOSAMINE
REDUCTASE

(Mycobacterium
tuberculosis) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		4 ILE A  93
GLN A 116
ILE A 114
GLU A 122
 None
 1.22A 4a99D-5jzxA:
undetectable		 4a99D-5jzxA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lae PEROXISOMAL
N(1)-ACETYL-SPERMINE
/SPERMIDINE
OXIDASE,PEROXISOMAL
N(1)-ACETYL-SPERMINE
/SPERMIDINE OXIDASE

(Mus musculus) 		PF01593
(Amino_oxidase) 		4 ILE A 183
ILE A 130
TYR A 127
GLU A 131
 None
 1.10A 4a99D-5laeA:
13.2		 4a99D-5laeA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mp0 M7GPPPN-MRNA
HYDROLASE

(Homo sapiens) 		PF00293
(NUDIX) 		4 GLN D 116
ILE D 194
TYR D 118
GLU D 193
 None
 1.25A 4a99D-5mp0D:
undetectable		 4a99D-5mp0D:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ns8 -

(-) 		no annotation 4 ILE A  78
ILE A  84
TYR A 144
GLU A 143
 None
 1.20A 4a99D-5ns8A:
undetectable		 4a99D-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nxy OSMOTICALLY
ACTIVATED
L-CARNITINE/CHOLINE
ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN OPUCC

(Bacillus
subtilis) 		no annotation 4 ILE A   8
GLN A  23
ILE A 233
GLU A 229
 None
 1.17A 4a99D-5nxyA:
undetectable		 4a99D-5nxyA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9g CHROMO
DOMAIN-CONTAINING
PROTEIN 1

(Saccharomyces
cerevisiae) 		no annotation 4 ILE W 549
ILE W 583
TYR W 582
GLU W 581
 None
 0.82A 4a99D-5o9gW:
undetectable		 4a99D-5o9gW:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb ORIGIN RECOGNITION
COMPLEX SUBUNIT 4

(Saccharomyces
cerevisiae) 		PF14629
(ORC4_C) 		4 ILE D  91
GLN D  88
ILE D  85
GLU D 115
 None
 1.21A 4a99D-5udbD:
undetectable		 4a99D-5udbD:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xav INTRACELLULAR
POLYHYDROXYALKANOATE
SYNTHASE

(Chromobacterium
sp. USM2) 		PF07167
(PhaC_N) 		4 ILE A 279
GLN A 199
ILE A 198
GLU A 196
 None
 0.79A 4a99D-5xavA:
undetectable		 4a99D-5xavA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bff AMINOGLYCOSIDE
ACETYLTRANSFERASE

(Escherichia
coli) 		no annotation 4 GLN A  73
ILE A  74
TYR A  75
GLU A  56
 None
 1.22A 4a99D-6bffA:
undetectable		 4a99D-6bffA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE

(Elizabethkingia
anophelis) 		no annotation 4 ILE A 334
ILE A 492
TYR A 488
GLU A 489
 None
 1.18A 4a99D-6bzcA:
undetectable		 4a99D-6bzcA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6e2q -

(-) 		no annotation 4 ILE A 104
ILE A  67
TYR A  62
GLU A  66
 None
 1.22A 4a99D-6e2qA:
undetectable		 4a99D-6e2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ehn CARBOHYDRATE
ESTERASE MZ0003

(unidentified
prokaryotic
organism) 		no annotation 4 ILE A 129
GLN A  81
ILE A  99
TYR A 100
 None
 1.15A 4a99D-6ehnA:
undetectable		 4a99D-6ehnA:
12.50