SIMILAR PATTERNS OF AMINO ACIDS FOR 4A97_J_ZPCJ1318_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1air PECTATE LYASE C

(Dickeya
chrysanthemi)
PF00544
(Pec_lyase_C)
4 PHE A 103
VAL A  82
ILE A  33
GLU A  60
None
1.02A 4a97I-1airA:
undetectable
4a97I-1airA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)


(Lactobacillus
sp. 30A)
PF01276
(OKR_DC_1)
PF03709
(OKR_DC_1_N)
PF03711
(OKR_DC_1_C)
4 VAL A 664
ARG A 245
ILE A 251
GLU A 671
None
1.08A 4a97I-1c4kA:
undetectable
4a97I-1c4kA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ciy CRYIA(A)

(Bacillus
thuringiensis)
PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N)
4 PHE A 574
TYR A 522
VAL A 524
ILE A 601
None
1.09A 4a97I-1ciyA:
4.1
4a97I-1ciyA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eth TRIACYLGLYCEROL
ACYL-HYDROLASE


(Sus scrofa)
PF00151
(Lipase)
PF01477
(PLAT)
4 PHE A 387
TYR A 341
VAL A 343
ILE A 419
None
0.99A 4a97I-1ethA:
0.0
4a97I-1ethA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f82 BOTULINUM NEUROTOXIN
TYPE B


(Clostridium
botulinum)
PF01742
(Peptidase_M27)
4 PHE A 154
VAL A 135
ARG A  27
ILE A 132
None
1.05A 4a97I-1f82A:
0.0
4a97I-1f82A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hnf CD2

(Homo sapiens)
PF05790
(C2-set)
PF07686
(V-set)
4 PHE A  98
TYR A  81
VAL A  83
ILE A  33
None
NA  A 629 (-4.7A)
None
None
0.86A 4a97I-1hnfA:
undetectable
4a97I-1hnfA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jc9 TECHYLECTIN-5A

(Tachypleus
tridentatus)
PF00147
(Fibrinogen_C)
4 TYR A  79
VAL A  78
ILE A  65
GLU A 256
None
1.04A 4a97I-1jc9A:
undetectable
4a97I-1jc9A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfu M-CALPAIN LARGE
SUBUNIT


(Homo sapiens)
PF00648
(Peptidase_C2)
PF01067
(Calpain_III)
PF13833
(EF-hand_8)
4 PHE L 475
VAL L 409
ILE L 499
GLU L 460
None
0.79A 4a97I-1kfuL:
0.0
4a97I-1kfuL:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lpb LIPASE

(Homo sapiens)
PF00151
(Lipase)
PF01477
(PLAT)
4 PHE B 386
TYR B 340
VAL B 342
ILE B 420
None
0.89A 4a97I-1lpbB:
0.0
4a97I-1lpbB:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nba N-CARBAMOYLSARCOSINE
AMIDOHYDROLASE


(Arthrobacter
sp.)
PF00857
(Isochorismatase)
4 VAL A  75
MET A  68
ILE A  71
GLU A 139
None
0.80A 4a97I-1nbaA:
undetectable
4a97I-1nbaA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nbq JUNCTIONAL ADHESION
MOLECULE 1


(Homo sapiens)
PF07686
(V-set)
PF13927
(Ig_3)
4 PHE A  55
TYR A  52
VAL A  31
GLU A 113
None
1.09A 4a97I-1nbqA:
undetectable
4a97I-1nbqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nf2 PHOSPHATASE

(Thermotoga
maritima)
PF08282
(Hydrolase_3)
4 TYR A  36
VAL A  38
ILE A  63
GLU A 208
None
1.02A 4a97I-1nf2A:
undetectable
4a97I-1nf2A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nt2 FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN


(Archaeoglobus
fulgidus)
PF01269
(Fibrillarin)
4 TYR A 208
VAL A 157
ILE A 130
GLU A 184
None
1.06A 4a97I-1nt2A:
undetectable
4a97I-1nt2A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfh PROTEIN (GELATION
FACTOR)


(Dictyostelium
discoideum)
PF00630
(Filamin)
4 TYR A 727
VAL A 745
MET A 741
ILE A 743
None
1.09A 4a97I-1qfhA:
2.2
4a97I-1qfhA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qjo DIHYDROLIPOAMIDE
ACETYLTRANSFERASE


(Escherichia
coli)
PF00364
(Biotin_lipoyl)
4 VAL A  65
MET A  72
ILE A  71
GLU A  38
None
0.99A 4a97I-1qjoA:
undetectable
4a97I-1qjoA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpk DNA POLYMERASE III,
BETA SUBUNIT


(Thermotoga
maritima)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
4 PHE A  68
VAL A  70
MET A  78
ILE A  75
None
1.06A 4a97I-1vpkA:
undetectable
4a97I-1vpkA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wxx HYPOTHETICAL PROTEIN
TTHA1280


(Thermus
thermophilus)
PF10672
(Methyltrans_SAM)
5 PHE A 335
TYR A 304
VAL A 339
ILE A 312
ASN A 308
None
1.35A 4a97I-1wxxA:
undetectable
4a97I-1wxxA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xl3 PROTEIN TYPE A

(Yersinia pestis)
PF09059
(TyeA)
4 PHE C  60
VAL C  16
MET C   9
ILE C  12
None
1.07A 4a97I-1xl3C:
4.4
4a97I-1xl3C:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xmx HYPOTHETICAL PROTEIN
VC1899


(Vibrio cholerae)
PF09002
(DUF1887)
4 PHE A 106
TYR A 109
VAL A  87
ILE A   3
None
0.92A 4a97I-1xmxA:
undetectable
4a97I-1xmxA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yal CHYMOPAPAIN

(Carica papaya)
PF00112
(Peptidase_C1)
4 VAL A 161
MET A 191
ILE A 177
ASN A 179
None
0.91A 4a97I-1yalA:
undetectable
4a97I-1yalA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e18 NH(3)-DEPENDENT
NAD(+) SYNTHETASE


(Pyrococcus
horikoshii)
PF02540
(NAD_synthase)
4 TYR A 197
VAL A 161
ILE A 153
ASN A 131
None
None
None
ZN  A1305 ( 4.9A)
0.98A 4a97I-2e18A:
undetectable
4a97I-2e18A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eaa 7S GLOBULIN-3

(Vigna angularis)
PF00190
(Cupin_1)
4 PHE A  47
TYR A  60
VAL A  62
ILE A 134
None
0.89A 4a97I-2eaaA:
undetectable
4a97I-2eaaA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eo4 150AA LONG
HYPOTHETICAL
HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN


(Sulfurisphaera
tokodaii)
PF01230
(HIT)
4 PHE A 111
TYR A 107
VAL A  73
ILE A  69
None
1.06A 4a97I-2eo4A:
undetectable
4a97I-2eo4A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ija ARYLAMINE
N-ACETYLTRANSFERASE
1


(Homo sapiens)
PF00797
(Acetyltransf_2)
4 TYR A  94
VAL A  93
ILE A 106
GLU A 182
UNX  A 502 (-4.3A)
None
None
None
1.04A 4a97I-2ijaA:
undetectable
4a97I-2ijaA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qc7 ENDOPLASMIC
RETICULUM PROTEIN
ERP29


(Homo sapiens)
PF07749
(ERp29)
PF07912
(ERp29_N)
4 PHE A  46
VAL A  91
ILE A  93
ASN A 101
None
1.05A 4a97I-2qc7A:
2.8
4a97I-2qc7A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qn0 NEUROTOXIN

(Clostridium
botulinum)
PF01742
(Peptidase_M27)
4 TYR A 202
VAL A 379
ILE A 256
GLU A 360
None
0.90A 4a97I-2qn0A:
undetectable
4a97I-2qn0A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uut RNA-DIRECTED RNA
POLYMERASE


(Sapporo virus)
PF00680
(RdRP_1)
4 PHE A 337
TYR A  90
VAL A  87
ILE A 261
None
1.09A 4a97I-2uutA:
undetectable
4a97I-2uutA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w8s PHOSPHONATE
MONOESTER HYDROLASE


(Paraburkholderia
caryophylli)
PF00884
(Sulfatase)
PF16347
(DUF4976)
4 TYR A 340
VAL A 439
ILE A 440
GLU A 343
None
0.99A 4a97I-2w8sA:
undetectable
4a97I-2w8sA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z3k LEUCYL/PHENYLALANYL-
TRNA-PROTEIN
TRANSFERASE


(Escherichia
coli)
PF03588
(Leu_Phe_trans)
4 TYR A  87
VAL A  89
MET A 144
ILE A 132
None
None
PHE  A 302 ( 3.6A)
None
0.86A 4a97I-2z3kA:
undetectable
4a97I-2z3kA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zi8 PROBABLE
BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE BPHC


(Mycobacterium
tuberculosis)
PF00903
(Glyoxalase)
4 PHE A 136
VAL A 218
MET A 257
ILE A 265
None
0.96A 4a97I-2zi8A:
undetectable
4a97I-2zi8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahi XYLULOSE
5-PHOSPHATE/FRUCTOSE
6-PHOSPHATE
PHOSPHOKETOLASE


(Bifidobacterium
breve)
PF03894
(XFP)
PF09363
(XFP_C)
PF09364
(XFP_N)
4 PHE A 504
TYR A 501
ASN A 549
GLU A 479
None
1.08A 4a97I-3ahiA:
undetectable
4a97I-3ahiA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ai7 XYLULOSE-5-PHOSPHATE
/FRUCTOSE-6-PHOSPHAT
E PHOSPHOKETOLASE


(Bifidobacterium
longum)
PF03894
(XFP)
PF09363
(XFP_C)
PF09364
(XFP_N)
4 PHE A 504
TYR A 501
ASN A 549
GLU A 479
None
1.10A 4a97I-3ai7A:
undetectable
4a97I-3ai7A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al8 SEMAPHORIN-6A

(Mus musculus)
PF01403
(Sema)
PF01437
(PSI)
4 PHE A 291
TYR A 292
ILE A 295
ASN A 294
None
1.10A 4a97I-3al8A:
undetectable
4a97I-3al8A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bm3 PSPGI RESTRICTION
ENDONUCLEASE


(Pyrococcus sp.
GI-H)
PF09019
(EcoRII-C)
4 PHE A 104
VAL A 159
ILE A 157
GLU A  60
None
0.89A 4a97I-3bm3A:
4.4
4a97I-3bm3A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfy MUCONATE
CYCLOISOMERASE


(Thermotoga
maritima)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 PHE A 201
VAL A 173
ARG A 143
ILE A 176
None
1.07A 4a97I-3dfyA:
undetectable
4a97I-3dfyA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dg8 BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE


(Plasmodium
falciparum)
PF00186
(DHFR_1)
4 VAL A 140
MET A 104
ILE A 126
ASN A 124
None
RJ6  A 609 ( 4.0A)
None
None
0.95A 4a97I-3dg8A:
undetectable
4a97I-3dg8A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3do9 UPF0302 PROTEIN
BA_1542/GBAA1542/BAS
1430


(Bacillus
anthracis)
PF08858
(IDEAL)
PF08864
(UPF0302)
4 TYR A  98
ARG A  56
ILE A  89
GLU A 117
None
1.06A 4a97I-3do9A:
undetectable
4a97I-3do9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwl ACTIN-RELATED
PROTEIN 2/3 COMPLEX
SUBUNIT 4


(Schizosaccharomyces
pombe)
PF05856
(ARPC4)
4 PHE F 138
VAL F 142
MET F 149
ILE F 146
None
1.09A 4a97I-3dwlF:
undetectable
4a97I-3dwlF:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ehf SENSOR KINASE (YOCF
PROTEIN)


(Bacillus
subtilis)
PF07730
(HisKA_3)
4 PHE A 264
VAL A 305
MET A 363
ILE A 316
None
1.06A 4a97I-3ehfA:
4.5
4a97I-3ehfA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ejg NON-STRUCTURAL
PROTEIN 3


(Human
coronavirus
229E)
PF01661
(Macro)
4 PHE A   6
TYR A  15
VAL A 150
ILE A 120
None
0.99A 4a97I-3ejgA:
undetectable
4a97I-3ejgA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eo6 PROTEIN OF UNKNOWN
FUNCTION (DUF1255)


(Acidithiobacillus
ferrooxidans)
PF06865
(DUF1255)
4 VAL A  59
MET A  83
ILE A  57
GLU A  97
None
1.00A 4a97I-3eo6A:
undetectable
4a97I-3eo6A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ewr NON-STRUCTURAL
PROTEIN 3


(Human
coronavirus
229E)
PF01661
(Macro)
4 PHE A   7
TYR A  16
VAL A 151
ILE A 121
None
None
APR  A 169 ( 4.6A)
None
0.94A 4a97I-3ewrA:
undetectable
4a97I-3ewrA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eya PYRUVATE
DEHYDROGENASE
[CYTOCHROME]


(Escherichia
coli)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 TYR A 200
MET A 306
ILE A 289
GLU A 324
None
1.02A 4a97I-3eyaA:
undetectable
4a97I-3eyaA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fbu ACETYLTRANSFERASE,
GNAT FAMILY


(Bacillus
anthracis)
PF13302
(Acetyltransf_3)
4 PHE A  90
VAL A  61
MET A   1
ILE A  10
COA  A 169 (-4.6A)
None
None
None
1.05A 4a97I-3fbuA:
undetectable
4a97I-3fbuA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ffh HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE


(Listeria
innocua)
PF00155
(Aminotran_1_2)
4 TYR A 233
VAL A  90
ILE A  94
GLU A 195
None
SO4  A 361 (-3.5A)
None
None
1.08A 4a97I-3ffhA:
undetectable
4a97I-3ffhA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ib5 SEX PHEROMONE
PRECURSOR


(Lactobacillus
salivarius)
PF07537
(CamS)
4 TYR A 146
VAL A 147
MET A 227
ILE A 172
None
0.81A 4a97I-3ib5A:
undetectable
4a97I-3ib5A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihp UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 5


(Homo sapiens)
PF00443
(UCH)
PF00627
(UBA)
PF02148
(zf-UBP)
4 PHE A 461
TYR A 568
VAL A 570
ILE A 827
None
1.09A 4a97I-3ihpA:
undetectable
4a97I-3ihpA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j82 C-TYPE LECTIN DOMAIN
FAMILY 9 MEMBER A


(Mus musculus)
PF00059
(Lectin_C)
4 TYR A 236
VAL A 198
MET A 181
ILE A 175
None
1.02A 4a97I-3j82A:
undetectable
4a97I-3j82A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2n SIGMA-54-DEPENDENT
TRANSCRIPTIONAL
REGULATOR


(Chlorobaculum
tepidum)
PF13185
(GAF_2)
4 PHE A  59
VAL A 135
ILE A 117
GLU A  60
None
1.08A 4a97I-3k2nA:
3.4
4a97I-3k2nA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1


(Homo sapiens)
PF00061
(Lipocalin)
4 PHE A  32
TYR A  37
VAL A  41
ILE A  44
None
1.00A 4a97I-3kq0A:
undetectable
4a97I-3kq0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ltf PROTEIN SPITZ

(Drosophila
melanogaster)
no annotation 4 PHE D  23
VAL D  25
ILE D  27
GLU D  36
None
0.92A 4a97I-3ltfD:
undetectable
4a97I-3ltfD:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ml6 CHIMERIC COMPLEX
BETWEEN PROTEIN
DISHEVLLED2 HOMOLOG
DVL-2 AND CLATHRIN
ADAPTOR AP-2 COMPLEX
SUBUNIT MU


(Mus musculus;
Rattus
norvegicus)
PF00610
(DEP)
PF00928
(Adap_comp_sub)
4 PHE A 469
TYR A 463
VAL A 466
MET A 430
None
1.05A 4a97I-3ml6A:
2.0
4a97I-3ml6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3muq UNCHARACTERIZED
CONSERVED PROTEIN


(Vibrio
parahaemolyticus)
PF12849
(PBP_like_2)
4 PHE A  91
TYR A  96
VAL A 225
ILE A 233
None
1.10A 4a97I-3muqA:
undetectable
4a97I-3muqA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3noy 4-HYDROXY-3-METHYLBU
T-2-EN-1-YL
DIPHOSPHATE SYNTHASE


(Aquifex
aeolicus)
PF04551
(GcpE)
4 PHE A 163
VAL A 127
MET A  93
ILE A 100
None
0.91A 4a97I-3noyA:
undetectable
4a97I-3noyA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3noy 4-HYDROXY-3-METHYLBU
T-2-EN-1-YL
DIPHOSPHATE SYNTHASE


(Aquifex
aeolicus)
PF04551
(GcpE)
4 VAL A 127
MET A  93
ILE A 100
GLU A 164
None
1.10A 4a97I-3noyA:
undetectable
4a97I-3noyA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN


(Escherichia
coli)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5)
4 VAL B 250
ILE B 246
ASN B 254
GLU B 334
None
1.01A 4a97I-3pcoB:
undetectable
4a97I-3pcoB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3um6 BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE


(Plasmodium
falciparum)
PF00186
(DHFR_1)
PF00303
(Thymidylat_synt)
4 VAL A 140
MET A 104
ILE A 126
ASN A 124
None
1CY  A 609 ( 4.5A)
None
None
0.81A 4a97I-3um6A:
undetectable
4a97I-3um6A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v9e LACCASE

(Botrytis aclada)
PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3)
4 PHE A 393
TYR A 397
VAL A 399
GLU A 390
None
1.01A 4a97I-3v9eA:
undetectable
4a97I-3v9eA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vtz GLUCOSE
1-DEHYDROGENASE


(Thermoplasma
volcanium)
PF13561
(adh_short_C2)
4 TYR A 109
VAL A 105
ILE A 101
ASN A 106
None
0.91A 4a97I-3vtzA:
undetectable
4a97I-3vtzA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vys HYDROGENASE
EXPRESSION/FORMATION
PROTEIN HYPD


(Thermococcus
kodakarensis)
PF01924
(HypD)
4 VAL B  58
ILE B  32
ASN B  57
GLU B  19
None
0.97A 4a97I-3vysB:
undetectable
4a97I-3vysB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wcy INTERFERON
ALPHA/BETA RECEPTOR
1


(Mus musculus)
PF01108
(Tissue_fac)
PF09294
(Interfer-bind)
4 TYR A 370
VAL A 372
MET A 352
ILE A 339
None
0.96A 4a97I-3wcyA:
2.0
4a97I-3wcyA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiq KOJIBIOSE
PHOSPHORYLASE


(Caldicellulosiruptor
saccharolyticus)
PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N)
4 PHE A 655
VAL A 307
ILE A 311
ASN A 310
None
0.92A 4a97I-3wiqA:
3.0
4a97I-3wiqA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bwf UBIQUITIN-CONJUGATIN
G ENZYME E2-21 KDA


(Saccharomyces
cerevisiae)
PF00179
(UQ_con)
4 ARG A 177
ILE A 102
ASN A 101
GLU A  62
None
0.93A 4a97I-4bwfA:
undetectable
4a97I-4bwfA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783


(Staphylococcus
aureus)
PF04507
(DUF576)
4 VAL A  95
ILE A  75
ASN A  77
GLU A 126
None
0.74A 4a97I-4eg9A:
undetectable
4a97I-4eg9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fyc THIOL:DISULFIDE
INTERCHANGE PROTEIN
(DSBC)


(Helicobacter
pylori)
PF13098
(Thioredoxin_2)
4 PHE A  67
TYR A 116
VAL A  83
ILE A 158
None
0.97A 4a97I-4fycA:
undetectable
4a97I-4fycA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpf POTASSIUM CHANNEL
SUBFAMILY U MEMBER 1


(Homo sapiens)
PF03493
(BK_channel_a)
4 TYR A 917
ILE A 472
ASN A 471
GLU A 558
None
1.09A 4a97I-4hpfA:
undetectable
4a97I-4hpfA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jz7 CARBAMATE KINASE

(Giardia
intestinalis)
PF00696
(AA_kinase)
4 VAL A  49
MET A 233
ILE A   9
GLU A 106
None
1.06A 4a97I-4jz7A:
undetectable
4a97I-4jz7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p27 VENOM ALLERGEN-LIKE
(VAL) 4 PROTEIN


(Schistosoma
mansoni)
PF00188
(CAP)
4 PHE A  14
VAL A  18
ILE A  27
GLU A  85
None
1.00A 4a97I-4p27A:
undetectable
4a97I-4p27A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p68 DIHYDROFOLATE
REDUCTASE


(Escherichia
coli)
PF00186
(DHFR_1)
4 VAL A  72
MET A  42
ILE A  61
ASN A  59
None
None
None
XCN  A  54 ( 3.0A)
0.83A 4a97I-4p68A:
undetectable
4a97I-4p68A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q8k ALGINASE

(Pseudoalteromonas
sp. SM0524)
PF08787
(Alginate_lyase2)
4 PHE A 239
TYR A 395
VAL A 393
ILE A 175
None
1.00A 4a97I-4q8kA:
undetectable
4a97I-4q8kA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q8l ALGINASE

(Pseudoalteromonas
sp. SM0524)
PF08787
(Alginate_lyase2)
4 PHE A  72
TYR A 228
VAL A 226
ILE A   8
None
0.98A 4a97I-4q8lA:
undetectable
4a97I-4q8lA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qni UNCHARACTERIZED
PROTEIN


(Bacteroides
thetaiotaomicron)
PF14274
(DUF4361)
PF16343
(DUF4973)
4 TYR A 328
VAL A 330
ILE A 200
ASN A 202
None
None
EDO  A 403 ( 4.1A)
EDO  A 403 ( 4.9A)
1.05A 4a97I-4qniA:
undetectable
4a97I-4qniA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rep GAMMA-CAROTENE
DESATURASE


(Nonlabens
dokdonensis)
PF01593
(Amino_oxidase)
4 VAL A 257
MET A 286
ILE A 250
GLU A 486
None
1.05A 4a97I-4repA:
undetectable
4a97I-4repA:
20.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL


(Dickeya
chrysanthemi)
PF02931
(Neur_chan_LBD)
6 PHE A  19
TYR A  38
VAL A  40
ARG A  91
MET A  93
ILE A 101
None
0.57A 4a97I-4twfA:
33.9
4a97I-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL


(Dickeya
chrysanthemi)
PF02931
(Neur_chan_LBD)
5 PHE A  19
VAL A  40
ARG A  91
MET A  93
ASN A 103
None
0.99A 4a97I-4twfA:
33.9
4a97I-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL


(Dickeya
chrysanthemi)
PF02931
(Neur_chan_LBD)
4 TYR A  38
ARG A  91
MET A  93
GLU A 150
None
0.78A 4a97I-4twfA:
33.9
4a97I-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL


(Dickeya
chrysanthemi;
Gloeobacter
violaceus)
PF02931
(Neur_chan_LBD)
7 PHE A  19
TYR A  38
VAL A  40
ARG A  91
MET A  93
ILE A 101
ASN A 103
None
0.60A 4a97I-4yeuA:
29.5
4a97I-4yeuA:
71.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aee ALPHA-GLUCOSIDASE
YIHQ


(Escherichia
coli)
PF01055
(Glyco_hydro_31)
4 PHE A 530
VAL A 564
ARG A 560
ILE A 678
None
0.92A 4a97I-5aeeA:
undetectable
4a97I-5aeeA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bsz N-METHYLTRANSFERASE

(Streptoalloteichus
sp. ATCC 53650)
PF13649
(Methyltransf_25)
4 VAL A 182
ARG A 184
ILE A 179
GLU A 124
None
EDO  A 302 ( 4.4A)
None
None
1.02A 4a97I-5bszA:
undetectable
4a97I-5bszA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czz CRISPR-ASSOCIATED
ENDONUCLEASE CAS9


(Staphylococcus
aureus)
PF13395
(HNH_4)
PF16592
(Cas9_REC)
4 ARG A 980
ILE A 982
ASN A 995
GLU A1006
None
0.97A 4a97I-5czzA:
undetectable
4a97I-5czzA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dxv RETHREADED DHFR

(synthetic
construct)
PF00186
(DHFR_1)
4 VAL A  89
MET A  59
ILE A  78
ASN A  76
None
0.77A 4a97I-5dxvA:
undetectable
4a97I-5dxvA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9o CELLULASE, GLYCOSYL
HYDROLASE FAMILY 5,
TPS LINKER, DOMAIN X


(Spirochaeta
thermophila)
no annotation 4 TYR A 526
ILE A 517
ASN A 503
GLU A 461
None
1.01A 4a97I-5e9oA:
undetectable
4a97I-5e9oA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flz SPINDLE POLE BODY
COMPONENT SPC98


(Saccharomyces
cerevisiae)
PF04130
(Spc97_Spc98)
4 TYR B 187
VAL B 188
ILE B 224
GLU B 182
None
0.95A 4a97I-5flzB:
2.8
4a97I-5flzB:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR


(Escherichia
coli;
Haliotis
rufescens)
PF11386
(VERL)
PF13416
(SBP_bac_8)
4 PHE A4106
VAL A4123
MET A4077
ILE A4070
None
0.86A 4a97I-5ii5A:
3.0
4a97I-5ii5A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iuj SENSOR HISTIDINE
KINASE DESK


(Bacillus
subtilis)
PF07730
(HisKA_3)
4 PHE A 264
VAL A 305
MET A 363
ILE A 316
None
1.06A 4a97I-5iujA:
3.1
4a97I-5iujA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jb3 30S RIBOSOMAL
PROTEIN S3


(Pyrococcus
abyssi)
PF00189
(Ribosomal_S3_C)
PF07650
(KH_2)
4 TYR Z 166
VAL Z 180
ILE Z 130
GLU Z  22
G  21010 ( 4.4A)
None
None
None
1.05A 4a97I-5jb3Z:
undetectable
4a97I-5jb3Z:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l0l UNCHARACTERIZED
PROTEIN


(Legionella
pneumophila)
no annotation 4 TYR A 130
VAL A 132
MET A 224
ILE A 144
None
0.77A 4a97I-5l0lA:
undetectable
4a97I-5l0lA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lmg DNA TOPOISOMERASE
2-ASSOCIATED PROTEIN
PAT1


(Saccharomyces
cerevisiae)
PF09770
(PAT1)
4 PHE A 681
VAL A 727
ILE A 724
GLU A 701
None
None
None
EDO  A 804 (-2.9A)
1.08A 4a97I-5lmgA:
2.9
4a97I-5lmgA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mc5 XAA-PRO DIPEPTIDASE

(Homo sapiens)
no annotation 4 PHE A  96
TYR A  83
VAL A  85
ILE A  45
None
0.64A 4a97I-5mc5A:
undetectable
4a97I-5mc5A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpd 26S PROTEASOME
REGULATORY SUBUNIT
RPN6


(Saccharomyces
cerevisiae)
PF01399
(PCI)
4 VAL Q 302
MET Q 271
ILE Q 270
GLU Q 322
None
0.86A 4a97I-5mpdQ:
2.3
4a97I-5mpdQ:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n0l GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY


(Clostridioides
difficile)
no annotation 4 PHE A  74
TYR A  78
VAL A  82
ILE A  85
ILE  A 201 ( 4.7A)
None
None
None
1.04A 4a97I-5n0lA:
undetectable
4a97I-5n0lA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5te1 ATP-CITRATE SYNTHASE

(Homo sapiens)
PF00549
(Ligase_CoA)
PF02629
(CoA_binding)
PF16114
(Citrate_bind)
4 PHE A 493
VAL A 568
ILE A 591
GLU A 683
None
1.04A 4a97I-5te1A:
undetectable
4a97I-5te1A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tet ATP-CITRATE SYNTHASE

(Homo sapiens)
PF00549
(Ligase_CoA)
PF02629
(CoA_binding)
4 PHE B 493
VAL B 568
ILE B 591
GLU B 683
None
1.05A 4a97I-5tetB:
undetectable
4a97I-5tetB:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tph DE NOVO NTF2
HOMODIMER


(synthetic
construct)
PF12680
(SnoaL_2)
4 PHE A  42
VAL A  37
MET A  89
ILE A 107
None
0.94A 4a97I-5tphA:
undetectable
4a97I-5tphA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5trv DENOVO NTF2

(synthetic
construct)
PF12680
(SnoaL_2)
4 PHE A  41
VAL A  36
MET A  88
ILE A 106
PEG  A 201 (-4.3A)
None
None
None
1.01A 4a97I-5trvA:
undetectable
4a97I-5trvA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uwb TOLUENE TOLERANCE
PROTEIN


(Pseudomonas
putida)
no annotation 4 TYR B 144
VAL B 164
ILE B 167
ASN B 165
PEF  B 302 (-4.0A)
PEF  B 302 ( 4.6A)
None
PEF  B 302 ( 4.1A)
1.03A 4a97I-5uwbB:
undetectable
4a97I-5uwbB:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yfb DIPEPTIDYL PEPTIDASE
3


(Armillaria
tabescens)
no annotation 4 TYR A 313
VAL A 314
ILE A 164
GLU A 324
None
0.95A 4a97I-5yfbA:
undetectable
4a97I-5yfbA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d46 BETA SLIDING CLAMP

(Rickettsia
typhi)
no annotation 4 PHE A 353
TYR A 352
VAL A 362
ILE A 376
None
1.01A 4a97I-6d46A:
undetectable
4a97I-6d46A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6


(Polytomella sp.
Pringsheim
198.80)
no annotation 4 PHE N 129
TYR N 126
VAL N 125
ILE N 120
None
1.08A 4a97I-6f36N:
undetectable
4a97I-6f36N:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fhs ARP5

(Chaetomium
thermophilum)
no annotation 4 VAL J  68
MET J 158
ILE J  61
ASN J  63
None
0.82A 4a97I-6fhsJ:
undetectable
4a97I-6fhsJ:
15.07