SIMILAR PATTERNS OF AMINO ACIDS FOR 4A97_E_ZPCE1318_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1akm ORNITHINE
TRANSCARBAMYLASE

(Escherichia
coli) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 GLU A  18
HIS A   5
VAL A 124
PHE A  14
 None
 1.22A 4a97E-1akmA:
0.0		 4a97E-1akmA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e8t HEMAGGLUTININ-NEURAM
INIDASE

(Avian
avulavirus 1) 		PF00423
(HN) 		4 PHE A 220
TYR A 185
HIS A 184
PHE A 221
 None
None
GOL  A1002 (-4.1A)
None
 1.01A 4a97E-1e8tA:
0.0		 4a97E-1e8tA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eu8 TREHALOSE/MALTOSE
BINDING PROTEIN

(Thermococcus
litoralis) 		PF01547
(SBP_bac_1) 		4 PHE A 315
TYR A  20
VAL A  11
PHE A 325
 None
 1.21A 4a97E-1eu8A:
0.0		 4a97E-1eu8A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE

(Brevibacterium
fuscum) 		PF00903
(Glyoxalase) 		4 GLU A 127
PHE A  79
TYR A  20
PHE A 129
 None
 1.10A 4a97E-1f1xA:
0.0		 4a97E-1f1xA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gbg (1,3-1,4)-BETA-D-GLU
CAN 4
GLUCANOHYDROLASE

(Bacillus
licheniformis) 		PF00722
(Glyco_hydro_16) 		4 GLU A  46
PHE A  10
TYR A 144
HIS A 145
 None
 1.11A 4a97E-1gbgA:
undetectable		 4a97E-1gbgA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofm CHONDROITINASE B

(Pedobacter
heparinus) 		PF14592
(Chondroitinas_B) 		4 GLU A 446
TYR A 197
HIS A 198
VAL A 232
 None
 1.07A 4a97E-1ofmA:
undetectable		 4a97E-1ofmA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis omega
virus) 		PF03566
(Peptidase_A21) 		4 PHE A 408
TYR A 341
VAL A 338
PHE A 325
 None
 1.18A 4a97E-1ohfA:
1.2		 4a97E-1ohfA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1paq TRANSLATION
INITIATION FACTOR
EIF-2B EPSILON
SUBUNIT

(Saccharomyces
cerevisiae) 		PF02020
(W2) 		4 TYR A 597
HIS A 598
VAL A 614
PHE A 648
 None
 1.04A 4a97E-1paqA:
undetectable		 4a97E-1paqA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfc PROTEIN (PURPLE ACID
PHOSPHATASE)

(Rattus
norvegicus) 		PF00149
(Metallophos) 		4 GLU A  69
PHE A  23
TYR A 104
VAL A  98
 None
 0.96A 4a97E-1qfcA:
0.0		 4a97E-1qfcA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qnh PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Plasmodium
falciparum) 		PF00160
(Pro_isomerase) 		4 TYR A  55
HIS A  54
VAL A 164
PHE A 119
 None
 1.20A 4a97E-1qnhA:
undetectable		 4a97E-1qnhA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v47 ATP SULFURYLASE

(Thermus
thermophilus) 		PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		4 PHE A  26
HIS A  77
VAL A 130
PHE A  32
 None
 1.22A 4a97E-1v47A:
undetectable		 4a97E-1v47A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9d DIAPHANOUS PROTEIN
HOMOLOG 1

(Mus musculus) 		PF02181
(FH2) 		4 PHE A 850
TYR A 854
VAL A 913
PHE A 906
 None
 1.15A 4a97E-1v9dA:
4.3		 4a97E-1v9dA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wst MULTIPLE SUBSTRATE
AMINOTRANSFERASE

(Thermococcus
profundus) 		PF00155
(Aminotran_1_2) 		4 GLU A 227
TYR A 100
HIS A 240
VAL A 107
 None
 1.13A 4a97E-1wstA:
undetectable		 4a97E-1wstA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wst MULTIPLE SUBSTRATE
AMINOTRANSFERASE

(Thermococcus
profundus) 		PF00155
(Aminotran_1_2) 		4 GLU A 227
TYR A 100
HIS A 240
VAL A 247
 None
 1.07A 4a97E-1wstA:
undetectable		 4a97E-1wstA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9q TRANSCRIPTIONAL
REGULATOR, HTH_3
FAMILY

(Vibrio cholerae) 		PF01381
(HTH_3) 		4 GLU A 128
TYR A 164
HIS A 115
VAL A 167
 ZN  A 202 ( 2.5A)
MED  A 201 ( 4.6A)
None
None
 1.13A 4a97E-1y9qA:
undetectable		 4a97E-1y9qA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvd SMAD UBIQUITINATION
REGULATORY FACTOR 2

(Homo sapiens) 		PF00632
(HECT) 		4 GLU A 404
TYR A 482
HIS A 479
PHE A 403
 None
 1.20A 4a97E-1zvdA:
undetectable		 4a97E-1zvdA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c47 CASEIN KINASE 1
GAMMA 2 ISOFORM

(Homo sapiens) 		PF00069
(Pkinase) 		4 GLU A 169
PHE A 130
TYR A 218
HIS A 240
 None
 1.14A 4a97E-2c47A:
2.3		 4a97E-2c47A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2esf CARBONIC ANHYDRASE 2

(Escherichia
coli) 		PF00484
(Pro_CA) 		4 GLU A 148
TYR A  99
HIS A 184
VAL A  47
 None
 1.07A 4a97E-2esfA:
undetectable		 4a97E-2esfA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g6y GREEN FLUORESCENT
PROTEIN 2

(Pontellina
plumata) 		PF01353
(GFP) 		4 PHE A  47
HIS A  98
VAL A 170
PHE A 121
 None
 1.04A 4a97E-2g6yA:
undetectable		 4a97E-2g6yA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gnp TRANSCRIPTIONAL
REGULATOR

(Streptococcus
pneumoniae) 		PF04198
(Sugar-bind) 		4 GLU A 160
PHE A 115
HIS A 129
VAL A 133
 None
 1.19A 4a97E-2gnpA:
undetectable		 4a97E-2gnpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hiv THERMOSTABLE DNA
LIGASE

(Sulfolobus
solfataricus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 GLU A 406
TYR A 259
HIS A 387
VAL A 413
 None
 1.04A 4a97E-2hivA:
undetectable		 4a97E-2hivA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hqj PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Leishmania
major) 		PF00160
(Pro_isomerase) 		4 TYR A  55
HIS A  54
VAL A 167
PHE A 122
 None
PO4  A 180 (-3.6A)
None
None
 1.20A 4a97E-2hqjA:
undetectable		 4a97E-2hqjA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jhq URACIL
DNA-GLYCOSYLASE

(Vibrio cholerae) 		PF03167
(UDG) 		4 GLU A  14
TYR A  19
VAL A  27
PHE A  20
 None
 1.16A 4a97E-2jhqA:
undetectable		 4a97E-2jhqA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qza SECRETED EFFECTOR
PROTEIN

(Salmonella
enterica) 		PF13599
(Pentapeptide_4)
PF13979
(SopA_C)
PF13981
(SopA) 		4 GLU A 396
HIS A 467
VAL A 474
PHE A 425
 None
 1.12A 4a97E-2qzaA:
2.0		 4a97E-2qzaA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vmf BETA-MANNOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2) 		4 GLU A  90
PHE A 156
TYR A 153
HIS A 151
 EDO  A1875 (-3.3A)
None
None
None
 1.08A 4a97E-2vmfA:
3.4		 4a97E-2vmfA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9

(Homo sapiens) 		PF06920
(DHR-2) 		4 TYR A 155
HIS A 229
VAL A 158
PHE A 287
 None
 0.77A 4a97E-2wmoA:
5.0		 4a97E-2wmoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xt6 2-OXOGLUTARATE
DECARBOXYLASE

(Mycolicibacterium
smegmatis) 		PF00198
(2-oxoacid_dh)
PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF16870
(OxoGdeHyase_C) 		4 GLU A 341
PHE A 339
TYR A 163
PHE A 224
 None
 1.11A 4a97E-2xt6A:
undetectable		 4a97E-2xt6A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z23 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Yersinia pestis) 		PF00496
(SBP_bac_5) 		4 GLU A 422
TYR A 420
HIS A 161
VAL A  48
 None
 1.04A 4a97E-2z23A:
undetectable		 4a97E-2z23A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zii VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 74

(Saccharomyces
cerevisiae) 		PF05719
(GPP34) 		4 PHE A 247
TYR A 294
VAL A 334
PHE A 296
 None
 1.14A 4a97E-2ziiA:
undetectable		 4a97E-2ziiA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5k TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 1

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 TYR A 176
HIS A 175
VAL A 213
PHE A 191
 None
 1.15A 4a97E-3a5kA:
undetectable		 4a97E-3a5kA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3adf MONOMERIC AZAMI
GREEN

(Galaxea
fascicularis) 		PF01353
(GFP) 		4 GLU A 144
TYR A 177
HIS A  88
VAL A 183
 None
 0.99A 4a97E-3adfA:
undetectable		 4a97E-3adfA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdl STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00565
(SNase)
PF00567
(TUDOR) 		4 GLU A 726
HIS A 670
VAL A 673
PHE A 737
 None
 1.05A 4a97E-3bdlA:
undetectable		 4a97E-3bdlA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3m EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4
GAMMA 2

(Homo sapiens) 		PF02020
(W2) 		4 GLU A 864
PHE A 866
HIS A 821
VAL A 769
 None
 1.08A 4a97E-3d3mA:
2.0		 4a97E-3d3mA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6e BETA-GLUCANASE

(Bacillus
licheniformis) 		PF00722
(Glyco_hydro_16) 		4 GLU A  33
PHE A  10
TYR A 131
HIS A 132
 None
 1.04A 4a97E-3d6eA:
undetectable		 4a97E-3d6eA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Bordetella
bronchiseptica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLU A  56
TYR A 309
HIS A 308
VAL A 149
 None
 1.19A 4a97E-3ddmA:
undetectable		 4a97E-3ddmA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dec BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 GLU A 335
TYR A 238
HIS A 237
VAL A 297
 None
 0.98A 4a97E-3decA:
1.6		 4a97E-3decA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eck PROTEIN
(HOMOPROTOCATECHUATE
2,3-DIOXYGENASE)

(Brevibacterium
fuscum) 		PF00903
(Glyoxalase) 		4 GLU A 127
PHE A  79
TYR A  20
PHE A 129
 None
 1.09A 4a97E-3eckA:
undetectable		 4a97E-3eckA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lqz HLA CLASS II
HISTOCOMPATIBILITY
ANTIGEN, DP ALPHA 1
CHAIN

(Homo sapiens) 		PF00993
(MHC_II_alpha)
PF07654
(C1-set) 		4 GLU A  21
HIS A 108
VAL A 165
PHE A 137
 None
 1.22A 4a97E-3lqzA:
3.6		 4a97E-3lqzA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n3u ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE IBPA

(Histophilus
somni) 		PF02661
(Fic) 		4 GLU A3751
TYR A3710
VAL A3704
PHE A3746
 None
 1.06A 4a97E-3n3uA:
undetectable		 4a97E-3n3uA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o5s BETA-GLUCANASE

(Bacillus
subtilis) 		PF00722
(Glyco_hydro_16) 		4 GLU A  74
PHE A  38
TYR A 172
HIS A 173
 None
 1.02A 4a97E-3o5sA:
undetectable		 4a97E-3o5sA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3piv INTERFERON

(Danio rerio) 		PF00143
(Interferon) 		4 GLU A  83
PHE A  85
HIS A  71
VAL A  75
 None
 1.12A 4a97E-3pivA:
2.2		 4a97E-3pivA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmi PWWP
DOMAIN-CONTAINING
PROTEIN MUM1

(Homo sapiens) 		no annotation 4 PHE A 466
TYR A 496
VAL A 521
PHE A 509
 None
 1.21A 4a97E-3pmiA:
undetectable		 4a97E-3pmiA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvt PHENYLACETIC ACID
DEGRADATION PROTEIN
PAAA

(Escherichia
coli) 		PF05138
(PaaA_PaaC) 		4 GLU A 263
PHE A 264
TYR A 110
VAL A  44
 None
3HC  A 310 (-4.8A)
None
None
 1.15A 4a97E-3pvtA:
undetectable		 4a97E-3pvtA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6t 43.2 KDA SALIVARY
PROTEIN

(Lutzomyia
longipalpis) 		PF03022
(MRJP) 		4 GLU A  57
TYR A 135
VAL A 138
PHE A  77
 None
 0.98A 4a97E-3q6tA:
undetectable		 4a97E-3q6tA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rnl SULFOTRANSFERASE

(Alicyclobacillus
acidocaldarius) 		PF13469
(Sulfotransfer_3) 		4 GLU A  85
TYR A  90
VAL A 174
PHE A   9
 None
 1.01A 4a97E-3rnlA:
undetectable		 4a97E-3rnlA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tgh GLIDEOSOME-ASSOCIATE
D PROTEIN 50

(Plasmodium
falciparum) 		PF00149
(Metallophos) 		4 PHE A  29
TYR A 153
HIS A 152
VAL A 102
 None
 1.05A 4a97E-3tghA:
undetectable		 4a97E-3tghA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3to3 PETROBACTIN
BIOSYNTHESIS PROTEIN
ASBB

(Bacillus
anthracis) 		PF04183
(IucA_IucC)
PF06276
(FhuF) 		4 GLU A 346
HIS A 436
VAL A 422
PHE A 457
 None
 1.04A 4a97E-3to3A:
undetectable		 4a97E-3to3A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		4 PHE A 206
HIS A 269
VAL A 255
PHE A 175
 NFA  A 213 ( 4.7A)
None
None
None
 1.01A 4a97E-3u0kA:
undetectable		 4a97E-3u0kA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0n MRUBY

(Entacmaea
quadricolor) 		PF01353
(GFP) 		4 PHE A  55
HIS A 118
VAL A 104
PHE A  24
 None
 1.14A 4a97E-3u0nA:
undetectable		 4a97E-3u0nA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ac3 BIFUNCTIONAL PROTEIN
GLMU

(Streptococcus
pneumoniae) 		PF00132
(Hexapep)
PF00483
(NTP_transferase)
PF14602
(Hexapep_2) 		4 GLU A 210
HIS A  95
VAL A  98
PHE A 205
 None
 1.20A 4a97E-4ac3A:
undetectable		 4a97E-4ac3A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4avx HEPATOCYTE GROWTH
FACTOR-REGULATED
TYROSINE KINASE
SUBSTRATE

(Homo sapiens) 		PF00790
(VHS)
PF01363
(FYVE) 		4 GLU A   9
TYR A  44
VAL A  79
PHE A   8
 None
EDO  A1234 (-4.1A)
None
None
 1.21A 4a97E-4avxA:
2.4		 4a97E-4avxA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4btm TAU-TUBULIN KINASE 1

(Homo sapiens) 		PF00069
(Pkinase) 		4 GLU A  71
PHE A 126
TYR A  73
VAL A  84
 None
 1.21A 4a97E-4btmA:
2.2		 4a97E-4btmA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dni FUSION PROTEIN OF
RNA-EDITING COMPLEX
PROTEINS MP42 AND
MP18

(Trypanosoma
brucei) 		PF00436
(SSB) 		4 GLU A 244
TYR A 131
HIS A 132
PHE A 251
 None
 1.16A 4a97E-4dniA:
undetectable		 4a97E-4dniA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e1q PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Triticum
aestivum) 		PF00160
(Pro_isomerase) 		4 TYR A  55
HIS A  54
VAL A 164
PHE A 119
 None
 1.21A 4a97E-4e1qA:
undetectable		 4a97E-4e1qA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4exw SINGLE-STRANDED
DNA-BINDING PROTEIN
DDRB

(Deinococcus
geothermalis) 		PF12747
(DdrB) 		4 GLU A  53
TYR A 103
VAL A  41
PHE A 131
 None
 1.20A 4a97E-4exwA:
undetectable		 4a97E-4exwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fiu HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 GLU A  63
HIS A 108
VAL A 113
PHE A  62
 None
 1.16A 4a97E-4fiuA:
undetectable		 4a97E-4fiuA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hy7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Triticum
aestivum) 		PF00160
(Pro_isomerase) 		4 TYR A  55
HIS A  54
VAL A 164
PHE A 119
 None
 1.20A 4a97E-4hy7A:
undetectable		 4a97E-4hy7A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i1f E3 UBIQUITIN-PROTEIN
LIGASE PARKIN

(Homo sapiens) 		PF01485
(IBR) 		4 PHE A 208
HIS A 461
VAL A 465
PHE A 210
 None
ZN  A 508 (-3.2A)
None
None
 1.08A 4a97E-4i1fA:
undetectable		 4a97E-4i1fA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i2y RGECO1

(Discosoma sp.;
Gallus gallus;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		4 PHE A 213
HIS A 263
VAL A  92
PHE A 286
 None
 1.04A 4a97E-4i2yA:
undetectable		 4a97E-4i2yA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifr 2-AMINO-3-CARBOXYMUC
ONATE 6-SEMIALDEHYDE
DECARBOXYLASE

(Pseudomonas
fluorescens) 		PF04909
(Amidohydro_2) 		4 GLU A  66
TYR A 295
HIS A  11
VAL A 117
 None
None
ZN  A 401 (-3.4A)
None
 1.16A 4a97E-4ifrA:
undetectable		 4a97E-4ifrA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k7d E3 UBIQUITIN-PROTEIN
LIGASE PARKIN

(Rattus
norvegicus) 		PF01485
(IBR) 		4 PHE A 208
HIS A 461
VAL A 465
PHE A 210
 None
ZN  A 508 (-3.3A)
None
None
 1.09A 4a97E-4k7dA:
undetectable		 4a97E-4k7dA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kvs ALDEHYDE
DECARBONYLASE

(Prochlorococcus
marinus) 		PF11266
(Ald_deCOase) 		4 GLU A  45
TYR A 135
HIS A 136
VAL A 141
 FE  A 302 ( 2.4A)
6NA  A 301 ( 4.9A)
None
None
 0.84A 4a97E-4kvsA:
2.5		 4a97E-4kvsA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4py3 BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS

(Bartonella sp.
1-1C) 		PF02661
(Fic) 		4 GLU A  75
PHE A  74
HIS A  17
PHE A  87
 None
 1.12A 4a97E-4py3A:
undetectable		 4a97E-4py3A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4z PNGF-II

(Elizabethkingia
meningoseptica) 		PF09112
(N-glycanase_N)
PF09113
(N-glycanase_C) 		4 GLU A 298
PHE A 349
VAL A 270
PHE A 296
 None
 1.17A 4a97E-4r4zA:
undetectable		 4a97E-4r4zA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgj CALCIUM-DEPENDENT
PROTEIN KINASE 4

(Plasmodium
falciparum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 GLU A 135
TYR A  70
VAL A  64
PHE A 137
 None
 1.15A 4a97E-4rgjA:
2.1		 4a97E-4rgjA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4thi PROTEIN (THIAMINASE
I)

(Bacillus
subtilis) 		PF01547
(SBP_bac_1) 		4 GLU A  43
PHE A  44
HIS A 282
VAL A 276
 None
None
SO4  A 372 (-3.7A)
None
 1.17A 4a97E-4thiA:
undetectable		 4a97E-4thiA:
22.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi) 		PF02931
(Neur_chan_LBD) 		4 GLU A 131
PHE A 133
TYR A 175
PHE A 188
 BR7  A 401 (-4.1A)
BR7  A 401 (-4.5A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
 0.55A 4a97E-4twfA:
33.7		 4a97E-4twfA:
99.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y07 NEDD4-LIKE E3
UBIQUITIN-PROTEIN
LIGASE WWP2

(Homo sapiens) 		PF00632
(HECT) 		4 GLU A 526
TYR A 604
HIS A 601
PHE A 525
 None
 1.19A 4a97E-4y07A:
undetectable		 4a97E-4y07A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y63 HISTO-BLOOD GROUP
ABO SYSTEM
TRANSFERASE

(Homo sapiens) 		PF03414
(Glyco_transf_6) 		4 GLU A 138
PHE A 133
HIS A 145
VAL A 204
 None
 1.19A 4a97E-4y63A:
undetectable		 4a97E-4y63A:
21.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL

(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		PF02931
(Neur_chan_LBD) 		5 GLU A 131
PHE A 133
TYR A 175
HIS A 177
PHE A 188
 None
 0.63A 4a97E-4yeuA:
29.4		 4a97E-4yeuA:
71.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zyn E3 UBIQUITIN-PROTEIN
LIGASE PARKIN

(Rattus
norvegicus) 		PF00240
(ubiquitin)
PF01485
(IBR) 		4 PHE A 208
HIS A 461
VAL A 465
PHE A 210
 None
ZN  A 508 (-3.5A)
None
None
 1.14A 4a97E-4zynA:
undetectable		 4a97E-4zynA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5an9 60S RIBOSOMAL
PROTEIN L23
60S RIBOSOMAL
PROTEIN L24

(Dictyostelium
discoideum) 		PF00238
(Ribosomal_L14)
PF01246
(Ribosomal_L24e) 		4 GLU G  37
PHE G  40
TYR E  94
VAL E 136
 G  N3388 ( 3.8A)
None
None
None
 1.16A 4a97E-5an9G:
undetectable		 4a97E-5an9G:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bmo PUTATIVE
UNCHARACTERIZED
PROTEIN LNMX

(Streptomyces
atroolivaceus) 		PF02585
(PIG-L) 		4 GLU A 161
PHE A 155
HIS A  88
VAL A  48
 None
 1.12A 4a97E-5bmoA:
undetectable		 4a97E-5bmoA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c5b DCC-INTERACTING
PROTEIN 13-BETA

(Homo sapiens) 		PF00169
(PH)
PF16746
(BAR_3) 		4 TYR B  88
HIS B  87
VAL B  82
PHE B 225
 None
 1.19A 4a97E-5c5bB:
5.3		 4a97E-5c5bB:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c7m E3 UBIQUITIN-PROTEIN
LIGASE ITCHY HOMOLOG

(Homo sapiens) 		PF00632
(HECT) 		4 GLU A 559
TYR A 637
HIS A 634
PHE A 558
 None
 1.19A 4a97E-5c7mA:
undetectable		 4a97E-5c7mA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c7m E3 UBIQUITIN-PROTEIN
LIGASE ITCHY HOMOLOG

(Homo sapiens) 		PF00632
(HECT) 		4 GLU A 559
TYR A 637
HIS A 634
PHE A 562
 None
 1.02A 4a97E-5c7mA:
undetectable		 4a97E-5c7mA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		4 GLU A 229
PHE A 222
TYR A 262
VAL A 240
 None
 0.88A 4a97E-5dqfA:
3.2		 4a97E-5dqfA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dux GALECTIN-4

(Homo sapiens) 		no annotation 4 TYR B 112
HIS B 111
VAL B 115
PHE B  50
 None
 1.11A 4a97E-5duxB:
undetectable		 4a97E-5duxB:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fav CHOLINE
TRIMETHYLAMINE-LYASE

(Desulfovibrio
alaskensis) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		4 GLU A 828
TYR A 428
VAL A 425
PHE A 825
 None
 0.95A 4a97E-5favA:
undetectable		 4a97E-5favA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		4 GLU A 230
PHE A 223
TYR A 263
VAL A 241
 None
 0.85A 4a97E-5ghkA:
2.8		 4a97E-5ghkA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hpk E3 UBIQUITIN-PROTEIN
LIGASE NEDD4-LIKE

(Homo sapiens) 		PF00632
(HECT) 		4 GLU A 609
TYR A 689
HIS A 686
PHE A 608
 None
 1.20A 4a97E-5hpkA:
undetectable		 4a97E-5hpkA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE

(Burkholderia
vietnamiensis) 		PF00483
(NTP_transferase) 		4 GLU A 161
PHE A 202
TYR A 249
VAL A 149
 None
 1.16A 4a97E-5i1fA:
undetectable		 4a97E-5i1fA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8k HHH1 FAB HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		5 GLU H   2
TYR H  32
HIS H  33
VAL H  76
PHE H  27
 None
 1.34A 4a97E-5i8kH:
undetectable		 4a97E-5i8kH:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m99 ALPHA-AMYLASE

(Thermotoga
petrophila) 		PF00128
(Alpha-amylase) 		4 GLU B 302
PHE B 310
TYR B 336
PHE B 309
 None
 1.19A 4a97E-5m99B:
undetectable		 4a97E-5m99B:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00565
(SNase)
PF00567
(TUDOR) 		4 GLU A 751
HIS A 695
VAL A 698
PHE A 762
 None
 1.01A 4a97E-5m9oA:
undetectable		 4a97E-5m9oA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nz7 CELLODEXTRIN
PHOSPHORYLASE

(Ruminiclostridium
thermocellum) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		4 GLU A 922
PHE A 459
TYR A 847
VAL A 853
 None
 1.09A 4a97E-5nz7A:
2.7		 4a97E-5nz7A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojj UBIQUITIN-CONJUGATIN
G ENZYME E2 T

(Homo sapiens) 		PF00179
(UQ_con) 		4 GLU A 131
TYR A  75
HIS A 150
PHE A 139
 None
 1.07A 4a97E-5ojjA:
undetectable		 4a97E-5ojjA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t1p ABC TRANSPORTER,
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN

(Campylobacter
jejuni) 		PF13343
(SBP_bac_6) 		4 GLU A 276
PHE A 277
TYR A 112
HIS A 299
 None
 1.20A 4a97E-5t1pA:
undetectable		 4a97E-5t1pA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5td7 ZGC:55652

(Danio rerio) 		PF00850
(Hist_deacetyl) 		4 GLU A  28
TYR A  16
HIS A 103
VAL A  74
 None
 1.22A 4a97E-5td7A:
undetectable		 4a97E-5td7A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4r VRC 315 53-1A09 FAB
HEAVY CHAIN

(Homo sapiens) 		no annotation 4 TYR A  32
HIS A  33
VAL A  78
PHE A  27
 None
 0.91A 4a97E-5u4rA:
undetectable		 4a97E-5u4rA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v9p LYSINE-SPECIFIC
DEMETHYLASE 5A

(Homo sapiens) 		PF00628
(PHD)
PF01388
(ARID)
PF02373
(JmjC)
PF02375
(JmjN)
PF02928
(zf-C5HC2)
PF08429
(PLU-1) 		4 GLU A 614
PHE A 666
HIS A 702
VAL A 653
 None
None
ZN  A 902 (-3.8A)
None
 1.11A 4a97E-5v9pA:
3.3		 4a97E-5v9pA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster) 		PF00023
(Ank)
PF00520
(Ion_trans)
PF12796
(Ank_2)
PF13637
(Ank_4) 		4 GLU A1120
PHE A1116
HIS A1054
VAL A1092
 None
 1.18A 4a97E-5vkqA:
3.4		 4a97E-5vkqA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5voc ENVELOPE
GLYCOPROTEIN H

(Human
betaherpesvirus
5) 		PF02489
(Herpes_glycop_H)
PF17488
(Herpes_glycoH_C) 		4 GLU A 339
PHE A 342
VAL A 128
PHE A 297
 None
 1.17A 4a97E-5vocA:
3.6		 4a97E-5vocA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wa2 SURFACE ANTIGEN

(Toxoplasma
gondii) 		no annotation 4 GLU A  79
TYR A 191
HIS A 189
PHE A 193
 None
 1.10A 4a97E-5wa2A:
undetectable		 4a97E-5wa2A:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wq3 CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE

(Corynebacterium
glutamicum) 		PF03641
(Lysine_decarbox) 		4 GLU A  56
PHE A  61
VAL A 104
PHE A 149
 1PE  A 301 ( 4.5A)
None
None
1PE  A 301 ( 4.8A)
 1.21A 4a97E-5wq3A:
undetectable		 4a97E-5wq3A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmc E3 UBIQUITIN-PROTEIN
LIGASE ITCHY

(Mus musculus) 		PF00397
(WW)
PF00632
(HECT) 		4 GLU A 520
TYR A 598
HIS A 595
PHE A 519
 None
 1.11A 4a97E-5xmcA:
2.4		 4a97E-5xmcA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmc E3 UBIQUITIN-PROTEIN
LIGASE ITCHY

(Mus musculus) 		PF00397
(WW)
PF00632
(HECT) 		4 GLU A 520
TYR A 598
HIS A 595
PHE A 523
 None
 1.04A 4a97E-5xmcA:
2.4		 4a97E-5xmcA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xya -

(-) 		no annotation 4 TYR A 610
HIS A 609
VAL A 565
PHE A 301
 None
 1.17A 4a97E-5xyaA:
undetectable		 4a97E-5xyaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cp2 -

(-) 		no annotation 4 GLU B 128
TYR B  75
VAL B 112
PHE B 136
 None
 1.17A 4a97E-6cp2B:
undetectable		 4a97E-6cp2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkh ATP SYNTHASE SUBUNIT
BETA, CHLOROPLASTIC

(Spinacia
oleracea) 		no annotation 4 GLU D 150
PHE D 149
TYR D 448
VAL D 437
 None
 1.13A 4a97E-6fkhD:
2.4		 4a97E-6fkhD:
18.40