SIMILAR PATTERNS OF AMINO ACIDS FOR 4A97_A_ZPCA1318_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1air | PECTATE LYASE C (Dickeyachrysanthemi) |
PF00544(Pec_lyase_C) | 4 | PHE A 103VAL A 82ILE A 33GLU A 60 | None | 1.05A | 4a97E-1airA:undetectable | 4a97E-1airA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bf6 | PHOSPHOTRIESTERASEHOMOLOGY PROTEIN (Escherichiacoli) |
PF02126(PTE) | 4 | PHE A 3VAL A 78ARG A 153ILE A 122 | None | 1.02A | 4a97E-1bf6A:0.0 | 4a97E-1bf6A:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ciy | CRYIA(A) (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 4 | PHE A 574TYR A 522VAL A 524ILE A 601 | None | 1.11A | 4a97E-1ciyA:2.7 | 4a97E-1ciyA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f82 | BOTULINUM NEUROTOXINTYPE B (Clostridiumbotulinum) |
PF01742(Peptidase_M27) | 4 | PHE A 154VAL A 135ARG A 27ILE A 132 | None | 1.00A | 4a97E-1f82A:0.0 | 4a97E-1f82A:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fns | VON WILLEBRANDFACTOR (Homo sapiens) |
PF00092(VWA) | 4 | PHE A 634TYR A 637VAL A 638GLU A 626 | None | 1.12A | 4a97E-1fnsA:0.0 | 4a97E-1fnsA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g60 | ADENINE-SPECIFICMETHYLTRANSFERASEMBOIIA (Moraxella bovis) |
PF01555(N6_N4_Mtase) | 4 | PHE A 73VAL A 28ILE A 206GLU A 117 | None | 1.09A | 4a97E-1g60A:undetectable | 4a97E-1g60A:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hnf | CD2 (Homo sapiens) |
PF05790(C2-set)PF07686(V-set) | 4 | PHE A 98TYR A 81VAL A 83ILE A 33 | None NA A 629 (-4.7A)NoneNone | 0.79A | 4a97E-1hnfA:0.0 | 4a97E-1hnfA:17.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nbq | JUNCTIONAL ADHESIONMOLECULE 1 (Homo sapiens) |
PF07686(V-set)PF13927(Ig_3) | 4 | PHE A 55TYR A 52VAL A 31GLU A 113 | None | 1.07A | 4a97E-1nbqA:0.0 | 4a97E-1nbqA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nf2 | PHOSPHATASE (Thermotogamaritima) |
PF08282(Hydrolase_3) | 4 | TYR A 36VAL A 38ILE A 63GLU A 208 | None | 1.04A | 4a97E-1nf2A:0.0 | 4a97E-1nf2A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nt2 | FIBRILLARIN-LIKEPRE-RRNA PROCESSINGPROTEIN (Archaeoglobusfulgidus) |
PF01269(Fibrillarin) | 4 | TYR A 208VAL A 157ILE A 130GLU A 184 | None | 1.10A | 4a97E-1nt2A:undetectable | 4a97E-1nt2A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uww | ENDOGLUCANASE (Bacillus akibai) |
PF03424(CBM_17_28) | 4 | PHE A 93TYR A 145VAL A 147ILE A 149 | None | 1.13A | 4a97E-1uwwA:undetectable | 4a97E-1uwwA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wkk | NUCLEOSIDEDIPHOSPHATE KINASE (Thermusthermophilus) |
PF00334(NDK) | 4 | ARG A 102ILE A 114ASN A 112GLU A 51 | GDP A1001 ( 4.7A)NoneGDP A1001 (-3.9A)None | 0.99A | 4a97E-1wkkA:undetectable | 4a97E-1wkkA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xew | SMC PROTEIN (Pyrococcusfuriosus) |
PF02463(SMC_N) | 4 | PHE X 12TYR X 15VAL X 82ILE X 84 | None | 0.94A | 4a97E-1xewX:undetectable | 4a97E-1xewX:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xmx | HYPOTHETICAL PROTEINVC1899 (Vibrio cholerae) |
PF09002(DUF1887) | 4 | PHE A 106TYR A 109VAL A 87ILE A 3 | None | 0.97A | 4a97E-1xmxA:undetectable | 4a97E-1xmxA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yf8 | BETA-GALACTOSIDE-SPECIFIC LECTIN 4 (Viscum album) |
PF00161(RIP) | 4 | PHE A 208VAL A 200ILE A 37ASN A 35 | None | 1.14A | 4a97E-1yf8A:undetectable | 4a97E-1yf8A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2az3 | NUCLEOSIDEDIPHOSPHATE KINASE (Halobacteriumsalinarum) |
PF00334(NDK) | 4 | ARG A 106ILE A 118ASN A 116GLU A 55 | CDP A1100 ( 4.8A)NoneCDP A1100 (-3.1A) MG A 201 ( 2.7A) | 1.08A | 4a97E-2az3A:undetectable | 4a97E-2az3A:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eaa | 7S GLOBULIN-3 (Vigna angularis) |
PF00190(Cupin_1) | 4 | PHE A 47TYR A 60VAL A 62ILE A 134 | None | 0.89A | 4a97E-2eaaA:undetectable | 4a97E-2eaaA:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hxv | DIAMINOHYDROXYPHOSPHORIBOSYLAMINOPYRIMIDINE DEAMINASE/5-AMINO-6-(5-PHOSPHORIBOSYLAMINO)URACILREDUCTASE (Thermotogamaritima) |
PF00383(dCMP_cyt_deam_1)PF01872(RibD_C) | 4 | PHE A 290VAL A 278ILE A 275GLU A 289 | NoneNoneNoneNDP A 400 (-2.9A) | 1.14A | 4a97E-2hxvA:undetectable | 4a97E-2hxvA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ija | ARYLAMINEN-ACETYLTRANSFERASE1 (Homo sapiens) |
PF00797(Acetyltransf_2) | 4 | TYR A 94VAL A 93ILE A 106GLU A 182 | UNX A 502 (-4.3A)NoneNoneNone | 1.07A | 4a97E-2ijaA:undetectable | 4a97E-2ijaA:24.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kq2 | RIBONUCLEASEH-RELATED PROTEIN (Desulfitobacteriumhafniense) |
PF00075(RNase_H) | 4 | PHE A 26VAL A 9ILE A 74GLU A 54 | None | 1.09A | 4a97E-2kq2A:undetectable | 4a97E-2kq2A:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lta | DE NOVO DESIGNEDPROTEIN (syntheticconstruct) |
PF01515(PTA_PTB) | 4 | TYR A 31VAL A 7ILE A 9GLU A 75 | None | 1.13A | 4a97E-2ltaA:undetectable | 4a97E-2ltaA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2okx | RHAMNOSIDASE B (Bacillus sp.GL1) |
PF05592(Bac_rhamnosid)PF08531(Bac_rhamnosid_N)PF17389(Bac_rhamnosid6H)PF17390(Bac_rhamnosid_C) | 4 | PHE A 806ILE A 626ASN A 628GLU A 809 | None | 1.09A | 4a97E-2okxA:3.8 | 4a97E-2okxA:16.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2paj | PUTATIVECYTOSINE/GUANINEDEAMINASE (unidentified) |
PF01979(Amidohydro_1) | 4 | PHE A 147VAL A 140ASN A 138GLU A 112 | None | 1.08A | 4a97E-2pajA:undetectable | 4a97E-2pajA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qc7 | ENDOPLASMICRETICULUM PROTEINERP29 (Homo sapiens) |
PF07749(ERp29)PF07912(ERp29_N) | 4 | PHE A 46VAL A 91ILE A 93ASN A 101 | None | 0.98A | 4a97E-2qc7A:2.8 | 4a97E-2qc7A:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qeu | PUTATIVECARBOXYMUCONOLACTONEDECARBOXYLASE (Paraburkholderiaxenovorans) |
PF02627(CMD) | 4 | VAL A 85ILE A 82ASN A 86GLU A 134 | NoneACT A 142 (-3.9A)ACT A 145 (-3.1A)None | 1.07A | 4a97E-2qeuA:2.8 | 4a97E-2qeuA:15.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjt | NICOTINAMIDE-NUCLEOTIDEADENYLYLTRANSFERASE (Francisellatularensis) |
no annotation | 4 | PHE B 51ILE B 33ASN B 94GLU B 52 | None | 1.14A | 4a97E-2qjtB:undetectable | 4a97E-2qjtB:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qn0 | NEUROTOXIN (Clostridiumbotulinum) |
PF01742(Peptidase_M27) | 4 | TYR A 202VAL A 379ILE A 256GLU A 360 | None | 0.88A | 4a97E-2qn0A:undetectable | 4a97E-2qn0A:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uut | RNA-DIRECTED RNAPOLYMERASE (Sapporo virus) |
PF00680(RdRP_1) | 4 | PHE A 337TYR A 90VAL A 87ILE A 261 | None | 1.14A | 4a97E-2uutA:undetectable | 4a97E-2uutA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yqu | 2-OXOGLUTARATEDEHYDROGENASE E3COMPONENT (Thermusthermophilus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | TYR A 265VAL A 303ILE A 284GLU A 31 | FAD A1601 (-4.8A)NoneNoneFAD A1601 (-2.7A) | 0.87A | 4a97E-2yquA:2.4 | 4a97E-2yquA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zua | NUCLEOSIDEDIPHOSPHATE KINASE (Haloarculaquadrata) |
PF00334(NDK) | 4 | ARG A 105ILE A 117ASN A 115GLU A 54 | None | 1.10A | 4a97E-2zuaA:undetectable | 4a97E-2zuaA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahi | XYLULOSE5-PHOSPHATE/FRUCTOSE6-PHOSPHATEPHOSPHOKETOLASE (Bifidobacteriumbreve) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 4 | PHE A 504TYR A 501ASN A 549GLU A 479 | None | 1.11A | 4a97E-3ahiA:undetectable | 4a97E-3ahiA:16.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ai7 | XYLULOSE-5-PHOSPHATE/FRUCTOSE-6-PHOSPHATE PHOSPHOKETOLASE (Bifidobacteriumlongum) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 4 | PHE A 504TYR A 501ASN A 549GLU A 479 | None | 1.13A | 4a97E-3ai7A:undetectable | 4a97E-3ai7A:15.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3al0 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNITC,LINKER,GLUTAMATE--TRNA LIGASE 2 (Thermotogamaritima;syntheticconstruct) |
PF00749(tRNA-synt_1c)PF02686(Glu-tRNAGln) | 4 | PHE C 371VAL C 143ILE C 351GLU C 374 | NoneNoneGSU C1001 (-4.4A)None | 1.09A | 4a97E-3al0C:undetectable | 4a97E-3al0C:16.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3al8 | SEMAPHORIN-6A (Mus musculus) |
PF01403(Sema)PF01437(PSI) | 4 | PHE A 291TYR A 292ILE A 295ASN A 294 | None | 1.11A | 4a97E-3al8A:undetectable | 4a97E-3al8A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bm3 | PSPGI RESTRICTIONENDONUCLEASE (Pyrococcus sp.GI-H) |
PF09019(EcoRII-C) | 4 | PHE A 104VAL A 159ILE A 157GLU A 60 | None | 1.10A | 4a97E-3bm3A:4.4 | 4a97E-3bm3A:23.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3doo | SHIKIMATEDEHYDROGENASE (Staphylococcusepidermidis) |
PF01488(Shikimate_DH)PF08501(Shikimate_dh_N) | 4 | TYR A 97VAL A 84ILE A 67GLU A 76 | None | 1.04A | 4a97E-3dooA:undetectable | 4a97E-3dooA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ejg | NON-STRUCTURALPROTEIN 3 (Humancoronavirus229E) |
PF01661(Macro) | 4 | PHE A 6TYR A 15VAL A 150ILE A 120 | None | 0.98A | 4a97E-3ejgA:undetectable | 4a97E-3ejgA:16.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewr | NON-STRUCTURALPROTEIN 3 (Humancoronavirus229E) |
PF01661(Macro) | 4 | PHE A 7TYR A 16VAL A 151ILE A 121 | NoneNoneAPR A 169 ( 4.6A)None | 0.94A | 4a97E-3ewrA:undetectable | 4a97E-3ewrA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g14 | NITROREDUCTASEFAMILY PROTEIN (Clostridiumnovyi) |
PF00881(Nitroreductase) | 4 | TYR A 45VAL A 84ILE A 48GLU A 89 | None | 1.08A | 4a97E-3g14A:undetectable | 4a97E-3g14A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gpg | NON-STRUCTURALPROTEIN 3 (Chikungunyavirus) |
PF01661(Macro) | 4 | VAL A 19ILE A 11ASN A 14GLU A 43 | None | 1.03A | 4a97E-3gpgA:undetectable | 4a97E-3gpgA:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihp | UBIQUITINCARBOXYL-TERMINALHYDROLASE 5 (Homo sapiens) |
PF00443(UCH)PF00627(UBA)PF02148(zf-UBP) | 4 | PHE A 461TYR A 568VAL A 570ILE A 827 | None | 1.11A | 4a97E-3ihpA:undetectable | 4a97E-3ihpA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k2n | SIGMA-54-DEPENDENTTRANSCRIPTIONALREGULATOR (Chlorobaculumtepidum) |
PF13185(GAF_2) | 4 | PHE A 59VAL A 135ILE A 117GLU A 60 | None | 1.12A | 4a97E-3k2nA:3.4 | 4a97E-3k2nA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kq0 | ALPHA-1-ACIDGLYCOPROTEIN 1 (Homo sapiens) |
PF00061(Lipocalin) | 4 | PHE A 32TYR A 37VAL A 41ILE A 44 | None | 1.08A | 4a97E-3kq0A:undetectable | 4a97E-3kq0A:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kre | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (Ehrlichiachaffeensis) |
PF01259(SAICAR_synt) | 4 | TYR A 229VAL A 232ILE A 171GLU A 196 | None | 1.13A | 4a97E-3kreA:undetectable | 4a97E-3kreA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ltg | PROTEIN SPITZ (Drosophilamelanogaster) |
PF00008(EGF) | 4 | PHE D 23VAL D 25ILE D 27GLU D 36 | None | 0.91A | 4a97E-3ltgD:undetectable | 4a97E-3ltgD:10.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nva | CTP SYNTHASE (Sulfolobussolfataricus) |
PF00117(GATase)PF06418(CTP_synth_N) | 4 | TYR A 5VAL A 7ILE A 143GLU A 165 | None | 1.10A | 4a97E-3nvaA:undetectable | 4a97E-3nvaA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pco | PHENYLALANYL-TRNASYNTHETASE, BETACHAIN (Escherichiacoli) |
PF01588(tRNA_bind)PF03147(FDX-ACB)PF03483(B3_4)PF03484(B5) | 4 | VAL B 250ILE B 246ASN B 254GLU B 334 | None | 1.09A | 4a97E-3pcoB:undetectable | 4a97E-3pcoB:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pg7 | NEUROFIBROMIN (Homo sapiens) |
PF13716(CRAL_TRIO_2) | 4 | PHE A1719VAL A1736ILE A1805GLU A1794 | None | 1.08A | 4a97E-3pg7A:undetectable | 4a97E-3pg7A:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pm0 | CYTOCHROME P450 1B1 (Homo sapiens) |
PF00067(p450) | 4 | TYR A 214VAL A 199ARG A 213ASN A 203 | None | 1.05A | 4a97E-3pm0A:undetectable | 4a97E-3pm0A:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ruc | WBGU (Plesiomonasshigelloides) |
PF01370(Epimerase) | 4 | TYR A 336VAL A 337ILE A 285GLU A 59 | None | 1.11A | 4a97E-3rucA:undetectable | 4a97E-3rucA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v9e | LACCASE (Botrytis aclada) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | PHE A 393TYR A 397VAL A 399GLU A 390 | None | 1.01A | 4a97E-3v9eA:undetectable | 4a97E-3v9eA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vtz | GLUCOSE1-DEHYDROGENASE (Thermoplasmavolcanium) |
PF13561(adh_short_C2) | 4 | TYR A 109VAL A 105ILE A 101ASN A 106 | None | 0.87A | 4a97E-3vtzA:undetectable | 4a97E-3vtzA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vvt | NUCLEOSIDEDIPHOSPHATE KINASE (-) |
PF00334(NDK) | 4 | ARG A 102ILE A 114ASN A 112GLU A 51 | None | 1.12A | 4a97E-3vvtA:undetectable | 4a97E-3vvtA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vys | HYDROGENASEEXPRESSION/FORMATIONPROTEIN HYPD (Thermococcuskodakarensis) |
PF01924(HypD) | 4 | VAL B 58ILE B 32ASN B 57GLU B 19 | None | 0.93A | 4a97E-3vysB:undetectable | 4a97E-3vysB:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wiq | KOJIBIOSEPHOSPHORYLASE (Caldicellulosiruptorsaccharolyticus) |
PF03632(Glyco_hydro_65m)PF03633(Glyco_hydro_65C)PF03636(Glyco_hydro_65N) | 4 | PHE A 655VAL A 307ILE A 311ASN A 310 | None | 0.94A | 4a97E-3wiqA:3.0 | 4a97E-3wiqA:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wq1 | ENDOGLUCANASE A (Pyrococcusfuriosus) |
PF01670(Glyco_hydro_12) | 4 | TYR A 281ARG A 187ILE A 191GLU A 279 | None | 1.09A | 4a97E-3wq1A:undetectable | 4a97E-3wq1A:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wr7 | SPERMIDINEN1-ACETYLTRANSFERASE (Escherichiacoli) |
PF13302(Acetyltransf_3) | 4 | TYR A 30VAL A 122ILE A 130ASN A 126 | COA A 202 (-3.4A)COA A 202 ( 4.8A)NoneCOA A 202 ( 4.7A) | 1.09A | 4a97E-3wr7A:undetectable | 4a97E-3wr7A:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ae0 | DIPHTHERIA TOXIN (Corynebacteriumdiphtheriae) |
PF01324(Diphtheria_R)PF02763(Diphtheria_C)PF02764(Diphtheria_T) | 4 | PHE A 17VAL A 135ILE A 150ASN A 151 | None | 0.90A | 4a97E-4ae0A:2.9 | 4a97E-4ae0A:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bih | UNCHARACTERIZEDLIPOPROTEINSAOUHSC_00053 (Staphylococcusaureus) |
PF04507(DUF576) | 4 | TYR A 125VAL A 127ILE A 134GLU A 122 | None | 1.06A | 4a97E-4bihA:undetectable | 4a97E-4bihA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bvt | CYANURIC ACIDAMIDOHYDROLASE (Pseudomonas sp.ADP) |
PF09663(Amido_AtzD_TrzD) | 4 | VAL A 292ARG A 8ILE A 289ASN A 291 | None | 1.12A | 4a97E-4bvtA:undetectable | 4a97E-4bvtA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bwf | UBIQUITIN-CONJUGATING ENZYME E2-21 KDA (Saccharomycescerevisiae) |
PF00179(UQ_con) | 4 | ARG A 177ILE A 102ASN A 101GLU A 62 | None | 1.03A | 4a97E-4bwfA:undetectable | 4a97E-4bwfA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c8q | DNA TOPOISOMERASE2-ASSOCIATED PROTEINPAT1 (Saccharomycescerevisiae) |
PF09770(PAT1) | 4 | PHE H 681VAL H 727ILE H 724GLU H 701 | NoneNoneNone CO H1080 (-3.8A) | 1.06A | 4a97E-4c8qH:undetectable | 4a97E-4c8qH:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4crn | ERF1 INRIBOSOME-BOUNDERF1-ERF3-GDPNPCOMPLEX (Saccharomycescerevisiae) |
PF03463(eRF1_1)PF03464(eRF1_2)PF03465(eRF1_3) | 4 | TYR X 277VAL X 5ILE X 387ASN X 8 | None | 1.11A | 4a97E-4crnX:undetectable | 4a97E-4crnX:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fyc | THIOL:DISULFIDEINTERCHANGE PROTEIN(DSBC) (Helicobacterpylori) |
PF13098(Thioredoxin_2) | 4 | PHE A 67TYR A 116VAL A 83ILE A 158 | None | 1.02A | 4a97E-4fycA:undetectable | 4a97E-4fycA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i8v | CYTOCHROME P450 1A1 (Homo sapiens) |
PF00067(p450) | 4 | TYR A 207VAL A 192ARG A 206ASN A 196 | None | 1.05A | 4a97E-4i8vA:undetectable | 4a97E-4i8vA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jso | OLIGOPEPTIDE ABCTRANSPORTER,PERIPLASMICOLIGOPEPTIDE-BINDINGPROTEIN (Thermotogamaritima) |
PF00496(SBP_bac_5) | 4 | PHE A 265VAL A 263ILE A 311GLU A 461 | None | 1.07A | 4a97E-4jsoA:undetectable | 4a97E-4jsoA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p27 | VENOM ALLERGEN-LIKE(VAL) 4 PROTEIN (Schistosomamansoni) |
PF00188(CAP) | 4 | PHE A 14VAL A 18ILE A 27GLU A 85 | None | 1.05A | 4a97E-4p27A:undetectable | 4a97E-4p27A:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvc | NADPH-DEPENDENTMETHYLGLYOXALREDUCTASE GRE2 (Saccharomycescerevisiae) |
PF01073(3Beta_HSD) | 4 | VAL A 101ILE A 98ASN A 102GLU A 182 | None | 1.05A | 4a97E-4pvcA:undetectable | 4a97E-4pvcA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q8k | ALGINASE (Pseudoalteromonassp. SM0524) |
PF08787(Alginate_lyase2) | 4 | PHE A 239TYR A 395VAL A 393ILE A 175 | None | 1.03A | 4a97E-4q8kA:undetectable | 4a97E-4q8kA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q8l | ALGINASE (Pseudoalteromonassp. SM0524) |
PF08787(Alginate_lyase2) | 4 | PHE A 72TYR A 228VAL A 226ILE A 8 | None | 1.02A | 4a97E-4q8lA:undetectable | 4a97E-4q8lA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qni | UNCHARACTERIZEDPROTEIN (Bacteroidesthetaiotaomicron) |
PF14274(DUF4361)PF16343(DUF4973) | 4 | TYR A 328VAL A 330ILE A 200ASN A 202 | NoneNoneEDO A 403 ( 4.1A)EDO A 403 ( 4.9A) | 1.03A | 4a97E-4qniA:undetectable | 4a97E-4qniA:20.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4twf | CYS-LOOPLIGAND-GATED IONCHANNEL (Dickeyachrysanthemi) |
PF02931(Neur_chan_LBD) | 5 | PHE A 19TYR A 38VAL A 40ARG A 91ILE A 101 | None | 0.48A | 4a97E-4twfA:33.7 | 4a97E-4twfA:99.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4twf | CYS-LOOPLIGAND-GATED IONCHANNEL (Dickeyachrysanthemi) |
PF02931(Neur_chan_LBD) | 4 | PHE A 19VAL A 40ARG A 91ASN A 103 | None | 0.91A | 4a97E-4twfA:33.7 | 4a97E-4twfA:99.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4twf | CYS-LOOPLIGAND-GATED IONCHANNEL (Dickeyachrysanthemi) |
PF02931(Neur_chan_LBD) | 4 | TYR A 38VAL A 40ARG A 91GLU A 150 | None | 0.72A | 4a97E-4twfA:33.7 | 4a97E-4twfA:99.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4upi | SULFATASE FAMILYPROTEIN (Ruegeriapomeroyi) |
PF00884(Sulfatase) | 4 | TYR A 332ARG A 16ILE A 291GLU A 261 | None | 0.90A | 4a97E-4upiA:undetectable | 4a97E-4upiA:21.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 6 | PHE A 19TYR A 38VAL A 40ARG A 91ILE A 101ASN A 103 | None | 0.57A | 4a97E-4yeuA:29.4 | 4a97E-4yeuA:71.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z81 | EGF FAMILYDOMAIN-CONTAININGPROTEIN (Toxoplasmagondii) |
PF02430(AMA-1)PF07974(EGF_2) | 4 | PHE A 367TYR A 368VAL A 370ILE A 154 | None | 1.14A | 4a97E-4z81A:undetectable | 4a97E-4z81A:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aee | ALPHA-GLUCOSIDASEYIHQ (Escherichiacoli) |
PF01055(Glyco_hydro_31) | 4 | PHE A 530VAL A 564ARG A 560ILE A 678 | None | 1.10A | 4a97E-5aeeA:undetectable | 4a97E-5aeeA:17.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b18 | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | TYR A 59VAL A 75ILE A 64GLU A 35 | None | 1.13A | 4a97E-5b18A:undetectable | 4a97E-5b18A:14.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5czz | CRISPR-ASSOCIATEDENDONUCLEASE CAS9 (Staphylococcusaureus) |
PF13395(HNH_4)PF16592(Cas9_REC) | 4 | ARG A 980ILE A 982ASN A 995GLU A1006 | None | 1.01A | 4a97E-5czzA:undetectable | 4a97E-5czzA:13.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9o | CELLULASE, GLYCOSYLHYDROLASE FAMILY 5,TPS LINKER, DOMAIN X (Spirochaetathermophila) |
no annotation | 4 | TYR A 526ILE A 517ASN A 503GLU A 461 | None | 0.89A | 4a97E-5e9oA:undetectable | 4a97E-5e9oA:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5flz | SPINDLE POLE BODYCOMPONENT SPC98 (Saccharomycescerevisiae) |
PF04130(Spc97_Spc98) | 4 | TYR B 187VAL B 188ILE B 224GLU B 182 | None | 0.99A | 4a97E-5flzB:2.8 | 4a97E-5flzB:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihr | PROBABLEBETA-GALACTOSIDASE A (Aspergillusniger) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 4 | PHE A 896VAL A 927ILE A 951ASN A 928 | None | 1.13A | 4a97E-5ihrA:undetectable | 4a97E-5ihrA:15.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lmg | DNA TOPOISOMERASE2-ASSOCIATED PROTEINPAT1 (Saccharomycescerevisiae) |
PF09770(PAT1) | 4 | PHE A 681VAL A 727ILE A 724GLU A 701 | NoneNoneNoneEDO A 804 (-2.9A) | 1.11A | 4a97E-5lmgA:3.1 | 4a97E-5lmgA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lw7 | ABC TRANSPORTERATP-BINDING PROTEIN (Pyrococcusabyssi) |
PF00005(ABC_tran)PF00037(Fer4)PF04068(RLI) | 4 | PHE B 322TYR B 288VAL B 286ILE B 284 | None | 1.12A | 4a97E-5lw7B:undetectable | 4a97E-5lw7B:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n0l | GTP-SENSINGTRANSCRIPTIONALPLEIOTROPICREPRESSOR CODY (Clostridioidesdifficile) |
no annotation | 4 | PHE A 74TYR A 78VAL A 82ILE A 85 | ILE A 201 ( 4.7A)NoneNoneNone | 1.00A | 4a97E-5n0lA:undetectable | 4a97E-5n0lA:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nck | N-ACETYLMANNOSAMINEKINASE (Fusobacteriumnucleatum) |
PF00480(ROK) | 4 | PHE A 194VAL A 237ILE A 132GLU A 197 | None | 1.09A | 4a97E-5nckA:undetectable | 4a97E-5nckA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nil | MACROLIDE EXPORTATP-BINDING/PERMEASEPROTEIN MACB (Escherichiacoli) |
PF00005(ABC_tran)PF02687(FtsX)PF12704(MacB_PCD) | 4 | PHE J 480VAL J 476ILE J 312ASN J 310 | None | 1.10A | 4a97E-5nilJ:2.0 | 4a97E-5nilJ:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5te1 | ATP-CITRATE SYNTHASE (Homo sapiens) |
PF00549(Ligase_CoA)PF02629(CoA_binding)PF16114(Citrate_bind) | 4 | PHE A 493VAL A 568ILE A 591GLU A 683 | None | 1.01A | 4a97E-5te1A:undetectable | 4a97E-5te1A:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tet | ATP-CITRATE SYNTHASE (Homo sapiens) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 4 | PHE B 493VAL B 568ILE B 591GLU B 683 | None | 1.00A | 4a97E-5tetB:undetectable | 4a97E-5tetB:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tv2 | ELONGATION FACTOR G (Vibriovulnificus) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2) | 4 | TYR A 10ARG A 335ASN A 12GLU A 8 | None | 1.01A | 4a97E-5tv2A:undetectable | 4a97E-5tv2A:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u7x | NOD FACTOR BINDINGLECTIN-NUCLEOTIDEPHOSPHOHYDROLASE (Vignaunguiculata) |
PF01150(GDA1_CD39) | 4 | TYR F 209VAL F 164ILE F 157GLU F 185 | None | 1.12A | 4a97E-5u7xF:undetectable | 4a97E-5u7xF:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5udy | ECTONUCLEOTIDEPYROPHOSPHATASE/PHOSPHODIESTERASE FAMILYMEMBER 7 (Homo sapiens) |
PF01663(Phosphodiest) | 4 | TYR A 194VAL A 36ILE A 243GLU A 171 | NoneNoneNoneFUC A 508 ( 4.3A) | 0.99A | 4a97E-5udyA:undetectable | 4a97E-5udyA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uwb | TOLUENE TOLERANCEPROTEIN (Pseudomonasputida) |
no annotation | 4 | TYR B 144VAL B 164ILE B 167ASN B 165 | PEF B 302 (-4.0A)PEF B 302 ( 4.6A)NonePEF B 302 ( 4.1A) | 0.97A | 4a97E-5uwbB:undetectable | 4a97E-5uwbB:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xns | CHROMOSOME PARTITIONPROTEIN SMC (Pyrococcusfuriosus) |
PF02463(SMC_N) | 4 | PHE A 12TYR A 15VAL A 82ILE A 84 | None | 0.99A | 4a97E-5xnsA:5.5 | 4a97E-5xnsA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yfb | DIPEPTIDYL PEPTIDASE3 (Armillariatabescens) |
no annotation | 4 | TYR A 313VAL A 314ILE A 164GLU A 324 | None | 1.02A | 4a97E-5yfbA:undetectable | 4a97E-5yfbA:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d46 | BETA SLIDING CLAMP (Rickettsiatyphi) |
no annotation | 4 | PHE A 353TYR A 352VAL A 362ILE A 376 | None | 0.99A | 4a97E-6d46A:undetectable | 4a97E-6d46A:17.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dfz | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Acroporamillepora) |
no annotation | 4 | VAL A 162ILE A 163ASN A 166GLU A 266 | None | 1.00A | 4a97E-6dfzA:undetectable | 4a97E-6dfzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f1v | CYTOPLASMIC DYNEIN 1HEAVY CHAIN 1 (Homo sapiens) |
no annotation | 4 | TYR f 527VAL f 523ILE f 520ASN f 524 | None | 1.06A | 4a97E-6f1vf:5.5 | 4a97E-6f1vf:12.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f36 | MITOCHONDRIAL ATPSYNTHASE SUBUNITASA6 (Polytomella sp.Pringsheim198.80) |
no annotation | 4 | PHE N 129TYR N 126VAL N 125ILE N 120 | None | 1.11A | 4a97E-6f36N:undetectable | 4a97E-6f36N:14.71 |