SIMILAR PATTERNS OF AMINO ACIDS FOR 4A83_A_DXCA1161

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a8p NADPH:FERREDOXIN
OXIDOREDUCTASE

(Azotobacter
vinelandii) 		PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		5 GLY A 143
VAL A 138
SER A 124
MET A 123
LEU A 119
 None
 1.31A 4a83A-1a8pA:
0.0		 4a83A-1a8pA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eom ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F3

(Elizabethkingia
meningoseptica) 		PF00704
(Glyco_hydro_18) 		5 TYR A  14
ASN A 275
SER A  61
MET A  59
LEU A  41
 NAG  A 632 ( 4.6A)
None
None
None
None
 1.45A 4a83A-1eomA:
0.0		 4a83A-1eomA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iy9 SPERMIDINE SYNTHASE

(Bacillus
subtilis) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		5 GLY A 234
VAL A  83
TYR A 173
ASN A 166
LEU A 180
 None
 1.07A 4a83A-1iy9A:
0.8		 4a83A-1iy9A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pss PHOTOSYNTHETIC
REACTION CENTER
PHOTOSYNTHETIC
REACTION CENTER

(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		PF00124
(Photo_RC)
PF00124
(Photo_RC) 		5 PHE L 146
TYR M 210
SER L 244
MET L 248
LEU L 131
 BCL  M   4 (-3.5A)
BCL  L   2 (-3.9A)
BCL  L   2 (-3.2A)
BCL  L   2 (-3.4A)
BCL  L   2 ( 4.3A)
 1.32A 4a83A-1pssL:
undetectable		 4a83A-1pssL:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uwi BETA-GALACTOSIDASE

(Sulfolobus
solfataricus) 		PF00232
(Glyco_hydro_1) 		5 GLY A 469
VAL A 419
TYR A 462
TYR A 422
ASN A 388
 None
 1.45A 4a83A-1uwiA:
0.0		 4a83A-1uwiA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfu CALMODULIN-SENSITIVE
ADENYLATE CYCLASE

(Bacillus
anthracis) 		PF03497
(Anthrax_toxA)
PF07737
(ATLF) 		5 ASP A 406
TYR A 363
ASN A 450
SER A 447
LEU A 435
 None
 1.37A 4a83A-1xfuA:
0.0		 4a83A-1xfuA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amy PHOSPHOMANNOMUTASE 2

(Homo sapiens) 		PF03332
(PMM) 		5 GLY A  42
VAL A 231
ASP A  12
MET A  28
LEU A  32
 None
 1.41A 4a83A-2amyA:
0.1		 4a83A-2amyA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hj9 AUTOINDUCER
2-BINDING
PERIPLASMIC PROTEIN
LUXP

(Vibrio harveyi) 		PF13407
(Peripla_BP_4) 		5 GLY A 183
PHE A 340
VAL A 176
TYR A  31
SER A  49
 None
 1.49A 4a83A-2hj9A:
0.0		 4a83A-2hj9A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE

(Arabidopsis
thaliana) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		5 GLY A  61
ASN A 348
SER A 381
MET A 413
LEU A 415
 None
K  A1463 (-3.9A)
None
None
None
 1.49A 4a83A-2ix4A:
undetectable		 4a83A-2ix4A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1b AMINOTRANSFERASE,
CLASS I

(Staphylococcus
aureus) 		PF00155
(Aminotran_1_2) 		5 GLY A 204
VAL A 242
TYR A  78
ASN A 279
LEU A 285
 None
 1.44A 4a83A-2o1bA:
undetectable		 4a83A-2o1bA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w40 GLYCEROL KINASE,
PUTATIVE

(Plasmodium
falciparum) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		5 GLY A 129
TYR A 131
SER A 399
MET A 401
LEU A 305
 None
EDO  A1506 (-4.3A)
None
None
None
 1.43A 4a83A-2w40A:
undetectable		 4a83A-2w40A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323

(Lactobacillus
plantarum) 		PF13472
(Lipase_GDSL_2) 		5 GLY A  96
PHE A 148
TYR A  69
ASN A  35
LEU A 202
 None
 1.44A 4a83A-3dc7A:
undetectable		 4a83A-3dc7A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfh MANDELATE RACEMASE

(Vibrionales
bacterium
SWAT-3) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 VAL A 141
ASP A 139
SER A 193
MET A 190
LEU A 156
 None
 1.48A 4a83A-3dfhA:
undetectable		 4a83A-3dfhA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3llk SULFHYDRYL OXIDASE 1

(Homo sapiens) 		PF04777
(Evr1_Alr) 		5 GLY A 395
PHE A 498
VAL A 409
ASP A 303
TYR A 300
 None
None
FAD  A 550 ( 4.8A)
None
None
 1.35A 4a83A-3llkA:
undetectable		 4a83A-3llkA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7h PUTIDACIN L1

(Pseudomonas
putida) 		PF01453
(B_lectin) 		5 GLY A 205
PHE A 201
ASN A 132
SER A 237
LEU A 230
 None
 1.12A 4a83A-3m7hA:
undetectable		 4a83A-3m7hA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nqh GLYCOSYL HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF04616
(Glyco_hydro_43) 		5 GLY A 368
PHE A 366
SER A 399
MET A 386
LEU A 426
 None
 1.47A 4a83A-3nqhA:
undetectable		 4a83A-3nqhA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s8i PROTEIN DDI1 HOMOLOG
1

(Homo sapiens) 		PF09668
(Asp_protease) 		5 GLY A 252
VAL A 302
SER A 269
MET A 328
LEU A 255
 None
 1.25A 4a83A-3s8iA:
undetectable		 4a83A-3s8iA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3saj GLUTAMATE RECEPTOR 1

(Rattus
norvegicus) 		PF01094
(ANF_receptor) 		5 GLY A  69
PHE A  90
ASN A  45
MET A  78
LEU A  79
 None
None
NAG  A 600 (-1.9A)
None
None
 1.47A 4a83A-3sajA:
undetectable		 4a83A-3sajA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t58 SULFHYDRYL OXIDASE 1

(Mus musculus) 		PF00085
(Thioredoxin)
PF04777
(Evr1_Alr) 		5 GLY A 398
PHE A 501
VAL A 412
ASP A 306
TYR A 303
 None
None
FAD  A 601 ( 4.8A)
None
None
 1.24A 4a83A-3t58A:
undetectable		 4a83A-3t58A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ti8 NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		5 GLY A 363
PHE A 374
SER A 441
MET A 426
LEU A 424
 None
 1.36A 4a83A-3ti8A:
undetectable		 4a83A-3ti8A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)

(Bacillus cereus) 		PF01497
(Peripla_BP_2) 		5 GLY A 264
PHE A 176
ASP A 257
TYR A  53
LEU A 272
 None
 1.18A 4a83A-3tnyA:
undetectable		 4a83A-3tnyA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ttg PUTATIVE
AMINOMETHYLTRANSFERA
SE

(Leptospirillum
rubarum) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		5 GLY A  16
VAL A 150
ASP A 168
TYR A 200
LEU A 183
 None
 1.39A 4a83A-3ttgA:
undetectable		 4a83A-3ttgA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x0y DSZC

(Rhodococcus
erythropolis) 		PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2) 		5 GLY A  91
VAL A  23
ASN A 124
SER A  59
LEU A  98
 None
 1.37A 4a83A-3x0yA:
undetectable		 4a83A-3x0yA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zh4 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Streptococcus
pneumoniae) 		PF00275
(EPSP_synthase) 		5 PHE A 130
TYR A  96
ASN A  89
MET A 144
LEU A 146
 None
 1.23A 4a83A-3zh4A:
undetectable		 4a83A-3zh4A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1

(Lupinus luteus) 		PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N) 		5 GLY A 290
PHE A 537
VAL A 511
TYR A 316
LEU A 519
 NAG  A 808 ( 4.5A)
NAG  A 808 (-4.7A)
None
FE  A 800 ( 4.3A)
None
 1.29A 4a83A-3zk4A:
undetectable		 4a83A-3zk4A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1

(Lupinus luteus) 		PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N) 		5 GLY A 516
PHE A 537
VAL A 511
TYR A 316
LEU A 519
 None
NAG  A 808 (-4.7A)
None
FE  A 800 ( 4.3A)
None
 1.48A 4a83A-3zk4A:
undetectable		 4a83A-3zk4A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4at3 BDNF/NT-3 GROWTH
FACTORS RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		5 GLY A 621
PHE A 619
VAL A 568
SER A 714
LEU A 608
 None
 1.09A 4a83A-4at3A:
undetectable		 4a83A-4at3A:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c94 FRA A 3 ALLERGEN

(Fragaria x
ananassa) 		PF00407
(Bet_v_1) 		5 LYS A  55
VAL A  68
TYR A  82
TYR A  84
LEU A 143
 None
 0.92A 4a83A-4c94A:
24.6		 4a83A-4c94A:
58.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ggp TRANS-2-ENOYL-COA
REDUCTASE

(Treponema
denticola) 		PF07055
(Eno-Rase_FAD_bd)
PF12241
(Enoyl_reductase)
PF12242
(Eno-Rase_NADH_b) 		5 PHE A 137
TYR A 109
ASN A  96
SER A  78
LEU A  50
 None
 1.44A 4a83A-4ggpA:
undetectable		 4a83A-4ggpA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p2l SULFHYDRYL OXIDASE 1

(Rattus
norvegicus) 		PF00085
(Thioredoxin)
PF04777
(Evr1_Alr) 		5 GLY A 398
PHE A 501
VAL A 412
ASP A 306
TYR A 303
 None
None
FAD  A 601 ( 4.7A)
None
None
 1.18A 4a83A-4p2lA:
undetectable		 4a83A-4p2lA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p6v NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT D
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E

(Vibrio
cholerae;
Vibrio cholerae) 		PF02508
(Rnf-Nqr)
PF02508
(Rnf-Nqr) 		5 GLY E 184
PHE D 188
VAL D  25
ASN E 119
LEU D  32
 None
 1.26A 4a83A-4p6vE:
undetectable		 4a83A-4p6vE:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rer 5'-AMP-ACTIVATED
PROTEIN KINASE
SUBUNIT GAMMA-1

(Homo sapiens) 		PF00571
(CBS) 		5 GLY G 218
VAL G 260
TYR G 241
ASN G 248
LEU G  95
 None
 1.49A 4a83A-4rerG:
undetectable		 4a83A-4rerG:
19.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4z3l MAJOR POLLEN
ALLERGEN BET V 1-A

(Betula pendula) 		PF00407
(Bet_v_1) 		8 PHE A  30
VAL A  67
TYR A  81
TYR A  83
ASN A 100
ASN A 118
SER A 136
LEU A 143
 None
 0.48A 4a83A-4z3lA:
27.9		 4a83A-4z3lA:
97.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4z3l MAJOR POLLEN
ALLERGEN BET V 1-A

(Betula pendula) 		PF00407
(Bet_v_1) 		8 PHE A  30
VAL A  67
TYR A  83
ASN A 100
ASN A 118
SER A 136
MET A 139
LEU A 143
 None
 0.59A 4a83A-4z3lA:
27.9		 4a83A-4z3lA:
97.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4z3l MAJOR POLLEN
ALLERGEN BET V 1-A

(Betula pendula) 		PF00407
(Bet_v_1) 		5 PHE A  30
VAL A  85
SER A 136
MET A 139
LEU A 143
 None
 1.04A 4a83A-4z3lA:
27.9		 4a83A-4z3lA:
97.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zkt BONTOXILYSIN A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		5 ASP A 759
ASN A 698
ASN A 694
SER A 766
LEU A 633
 None
 1.49A 4a83A-4zktA:
undetectable		 4a83A-4zktA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5by3 BTGH115A

(Bacteroides
thetaiotaomicron) 		PF15979
(Glyco_hydro_115) 		5 GLY A 253
VAL A 187
ASN A 228
ASN A 196
MET A 175
 None
 1.31A 4a83A-5by3A:
undetectable		 4a83A-5by3A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cyl FIMBRIAL SUBUNIT
CUPB6

(Pseudomonas
aeruginosa) 		PF00419
(Fimbrial) 		5 GLY A 196
VAL A 145
TYR A 185
ASN A 152
ASN A  62
 None
 1.40A 4a83A-5cylA:
undetectable		 4a83A-5cylA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ejj UFM1-SPECIFIC
PROTEASE

(Caenorhabditis
elegans) 		PF07910
(Peptidase_C78) 		5 VAL A  57
ASP A  18
ASN A  25
ASN A 338
LEU A 108
 None
 1.36A 4a83A-5ejjA:
undetectable		 4a83A-5ejjA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN

(Trichomonas
vaginalis) 		PF00266
(Aminotran_5) 		5 GLY A 344
PHE A 308
VAL A 281
ASN A 304
ASN A 156
 None
 1.39A 4a83A-5f8vA:
undetectable		 4a83A-5f8vA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsl 778AA LONG
HYPOTHETICAL
BETA-GALACTOSIDASE

(Pyrococcus
horikoshii) 		PF02449
(Glyco_hydro_42) 		5 GLY A 444
PHE A 443
TYR A 449
ASN A 467
LEU A 479
 None
 1.28A 4a83A-5gslA:
undetectable		 4a83A-5gslA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsz KINESIN-LIKE PROTEIN
KIF19

(Mus musculus) 		PF00225
(Kinesin) 		5 GLY A 341
PHE A  67
LYS A  63
SER A 324
LEU A  16
 None
 1.49A 4a83A-5gszA:
undetectable		 4a83A-5gszA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ic7 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		no annotation 5 PHE A 330
VAL A 357
SER A 317
MET A 298
LEU A 290
 None
 1.29A 4a83A-5ic7A:
undetectable		 4a83A-5ic7A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jmd HEPARINASE III
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF07940
(Hepar_II_III)
PF16889
(Hepar_II_III_N) 		5 VAL A 535
ASP A 533
TYR A 547
ASN A 608
SER A 542
 None
 1.27A 4a83A-5jmdA:
2.5		 4a83A-5jmdA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w21 KLOTHO

(Homo sapiens) 		no annotation 5 GLY A 505
PHE A 506
TYR A 497
TYR A 455
ASN A 415
 None
 1.28A 4a83A-5w21A:
undetectable		 4a83A-5w21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w21 KLOTHO

(Homo sapiens) 		no annotation 5 GLY A 505
VAL A 452
TYR A 497
TYR A 455
ASN A 415
 None
 1.09A 4a83A-5w21A:
undetectable		 4a83A-5w21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w21 KLOTHO

(Homo sapiens) 		no annotation 5 GLY A 952
PHE A 953
TYR A 944
TYR A 912
ASN A 873
 None
 1.39A 4a83A-5w21A:
undetectable		 4a83A-5w21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wan PYRIMIDINE
MONOOXYGENASE RUTA

(Escherichia
coli) 		PF00296
(Bac_luciferase) 		5 GLY A 338
PHE A 332
LYS A 256
TYR A 309
LEU A 330
 None
 1.38A 4a83A-5wanA:
undetectable		 4a83A-5wanA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aun PLA2G6, IPLA2BETA

(Cricetulus
griseus) 		no annotation 5 GLY A 468
ASP A 598
ASN A 593
SER A 503
LEU A 510
 None
 1.45A 4a83A-6aunA:
undetectable		 4a83A-6aunA:
undetectable