SIMILAR PATTERNS OF AMINO ACIDS FOR 4A7T_A_5FWA1002_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e8t | HEMAGGLUTININ-NEURAMINIDASE (Avianavulavirus 1) |
PF00423(HN) | 3 | ASN A 298TRP A 295ASP A 261 | NoneNone CA A1001 (-3.6A) | 1.26A | 4a7tA-1e8tA:0.04a7tF-1e8tA:0.0 | 4a7tA-1e8tA:17.344a7tF-1e8tA:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ece | ENDOCELLULASE E1 (Acidothermuscellulolyticus) |
PF00150(Cellulase) | 3 | ASN A 27TRP A 319ASP A 158 | NoneBGC A 403 ( 4.2A)None | 1.24A | 4a7tA-1eceA:0.04a7tF-1eceA:0.0 | 4a7tA-1eceA:17.784a7tF-1eceA:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gq1 | CYTOCHROME CD1NITRITE REDUCTASE (Paracoccuspantotrophus) |
PF02239(Cytochrom_D1)PF13442(Cytochrome_CBB3) | 3 | ASN A 161TRP A 163ASP A 224 | None | 1.30A | 4a7tA-1gq1A:0.04a7tF-1gq1A:0.0 | 4a7tA-1gq1A:16.144a7tF-1gq1A:16.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gzj | EGI (Thermoascusaurantiacus) |
PF00150(Cellulase) | 3 | ASN A 10TRP A 273ASP A 129 | None | 1.22A | 4a7tA-1gzjA:undetectable4a7tF-1gzjA:0.0 | 4a7tA-1gzjA:20.884a7tF-1gzjA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h3e | TYROSYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00579(tRNA-synt_1b) | 3 | ASN A 128TRP A 131ASP A 45 | TYE A1434 ( 4.8A)NoneTYE A1434 ( 3.8A) | 0.80A | 4a7tA-1h3eA:0.14a7tF-1h3eA:0.2 | 4a7tA-1h3eA:16.034a7tF-1h3eA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j6x | AUTOINDUCER-2PRODUCTION PROTEINLUXS (Helicobacterpylori) |
PF02664(LuxS) | 3 | ASN A 127TRP A 124ASP A 50 | None | 1.30A | 4a7tA-1j6xA:0.04a7tF-1j6xA:0.0 | 4a7tA-1j6xA:19.764a7tF-1j6xA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jik | TYROSYL-TRNASYNTHETASE (Staphylococcusaureus) |
PF00579(tRNA-synt_1b) | 3 | ASN A 124TRP A 127ASP A 40 | 545 A 421 (-4.4A)None545 A 421 (-3.7A) | 0.87A | 4a7tA-1jikA:undetectable4a7tF-1jikA:undetectable | 4a7tA-1jikA:16.674a7tF-1jikA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k38 | BETA-LACTAMASE OXA-2 (Salmonellaenterica) |
PF00905(Transpeptidase) | 3 | ASN A 231TRP A 214ASP A 55 | None | 1.18A | 4a7tA-1k38A:0.04a7tF-1k38A:0.0 | 4a7tA-1k38A:20.704a7tF-1k38A:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lc7 | L-THREONINE-O-3-PHOSPHATE DECARBOXYLASE (Salmonellaenterica) |
PF00155(Aminotran_1_2) | 3 | ASN A 230TRP A 209ASP A 233 | None | 1.18A | 4a7tA-1lc7A:0.04a7tF-1lc7A:0.0 | 4a7tA-1lc7A:18.184a7tF-1lc7A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgd | PROTEIN(TRANSKETOLASE) (Escherichiacoli) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 3 | ASN A 9TRP A 279ASP A 35 | None | 1.19A | 4a7tA-1qgdA:undetectable4a7tF-1qgdA:undetectable | 4a7tA-1qgdA:13.314a7tF-1qgdA:13.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgi | PROTEIN(CHITOSANASE) (Bacilluscirculans) |
PF01374(Glyco_hydro_46) | 3 | ASN A 227TRP A 256ASP A 215 | None | 1.22A | 4a7tA-1qgiA:undetectable4a7tF-1qgiA:undetectable | 4a7tA-1qgiA:22.624a7tF-1qgiA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szn | ALPHA-GALACTOSIDASE (Trichodermareesei) |
PF16499(Melibiase_2) | 3 | ASN A 133TRP A 205ASP A 142 | GOL A 901 (-2.9A)NoneGOL A 901 (-3.7A) | 1.12A | 4a7tA-1sznA:undetectable4a7tF-1sznA:undetectable | 4a7tA-1sznA:18.474a7tF-1sznA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tyd | TYROSYL-TRNASYNTHETASE (Geobacillusstearothermophilus) |
PF00579(tRNA-synt_1b) | 3 | ASN E 123TRP E 126ASP E 38 | TYR E 320 ( 4.7A)NoneTYR E 320 (-3.6A) | 0.85A | 4a7tA-1tydE:undetectable4a7tF-1tydE:undetectable | 4a7tA-1tydE:17.614a7tF-1tydE:17.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vbm | TYROSYL-TRNASYNTHETASE (Escherichiacoli) |
PF00579(tRNA-synt_1b) | 3 | ASN A 126TRP A 129ASP A 41 | YSA A3001 ( 4.9A)NoneYSA A3001 (-3.9A) | 1.01A | 4a7tA-1vbmA:undetectable4a7tF-1vbmA:undetectable | 4a7tA-1vbmA:18.874a7tF-1vbmA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2csg | PUTATIVE CYTOPLASMICPROTEIN (Salmonellaenterica) |
PF07350(DUF1479) | 3 | ASN A 113TRP A 400ASP A 108 | None | 1.27A | 4a7tA-2csgA:undetectable4a7tF-2csgA:undetectable | 4a7tA-2csgA:20.214a7tF-2csgA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e8y | AMYX PROTEIN (Bacillussubtilis) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 3 | ASN A 399TRP A 202ASP A 401 | None | 0.89A | 4a7tA-2e8yA:undetectable4a7tF-2e8yA:3.7 | 4a7tA-2e8yA:15.554a7tF-2e8yA:15.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hes | YDR267CP (Saccharomycescerevisiae) |
PF00400(WD40) | 3 | ASN X 322TRP X 324ASP X 318 | None | 1.26A | 4a7tA-2hesX:undetectable4a7tF-2hesX:undetectable | 4a7tA-2hesX:17.424a7tF-2hesX:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2osy | ENDOGLYCOCERAMIDASEII (Rhodococcus sp.) |
PF00150(Cellulase) | 3 | ASN A 60TRP A 382ASP A 229 | NoneGLC A 600 ( 3.5A)None | 1.16A | 4a7tA-2osyA:undetectable4a7tF-2osyA:undetectable | 4a7tA-2osyA:14.734a7tF-2osyA:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pid | TYROSYL-TRNASYNTHETASE (Homo sapiens) |
PF00579(tRNA-synt_1b) | 3 | ASN A 173TRP A 176ASP A 81 | YSA A 384 ( 4.8A)NoneYSA A 384 (-3.9A) | 0.78A | 4a7tA-2pidA:undetectable4a7tF-2pidA:undetectable | 4a7tA-2pidA:17.614a7tF-2pidA:17.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qp4 | BILE SALTSULFOTRANSFERASE (Homo sapiens) |
PF00685(Sulfotransfer_1) | 3 | ASN A 122TRP A 284ASP A 253 | None | 1.15A | 4a7tA-2qp4A:undetectable4a7tF-2qp4A:undetectable | 4a7tA-2qp4A:20.384a7tF-2qp4A:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ts1 | TYROSYL-TRNASYNTHETASE (Geobacillusstearothermophilus) |
PF00579(tRNA-synt_1b) | 3 | ASN A 123TRP A 126ASP A 38 | None | 0.91A | 4a7tA-2ts1A:undetectable4a7tF-2ts1A:undetectable | 4a7tA-2ts1A:18.444a7tF-2ts1A:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vca | ALPHA-N-ACETYLGLUCOSAMINIDASE (Clostridiumperfringens) |
PF00754(F5_F8_type_C)PF05089(NAGLU)PF12971(NAGLU_N)PF12972(NAGLU_C) | 3 | ASN A 325TRP A 321ASP A 615 | None | 1.00A | 4a7tA-2vcaA:undetectable4a7tF-2vcaA:undetectable | 4a7tA-2vcaA:10.184a7tF-2vcaA:10.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wda | PUTATIVE SECRETEDLYASE (Streptomycesviolaceoruber) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 3 | ASN A 557TRP A 615ASP A 456 | FMT A1769 (-4.5A)PEG A1782 (-3.2A)FMT A1769 (-3.5A) | 0.99A | 4a7tA-2wdaA:undetectable4a7tF-2wdaA:1.2 | 4a7tA-2wdaA:12.354a7tF-2wdaA:12.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wkn | FORMAMIDASE (Delftiaacidovorans) |
PF03069(FmdA_AmdA) | 3 | ASN A 54TRP A 102ASP A 56 | None | 1.13A | 4a7tA-2wknA:undetectable4a7tF-2wknA:undetectable | 4a7tA-2wknA:19.124a7tF-2wknA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wn4 | ADP-RIBOSYLTRANSFERASE ENZYMATICCOMPONENT (Clostridioidesdifficile) |
PF03496(ADPrib_exo_Tox) | 3 | ASN A 234TRP A 230ASP A 237 | None | 1.13A | 4a7tA-2wn4A:undetectable4a7tF-2wn4A:undetectable | 4a7tA-2wn4A:14.294a7tF-2wn4A:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y9x | POLYPHENOL OXIDASE (Agaricusbisporus) |
PF00264(Tyrosinase) | 3 | ASN A 298TRP A 138ASP A 367 | None | 1.06A | 4a7tA-2y9xA:undetectable4a7tF-2y9xA:undetectable | 4a7tA-2y9xA:16.454a7tF-2y9xA:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3axx | 458AA LONGHYPOTHETICALENDO-1,4-BETA-GLUCANASE (Pyrococcushorikoshii) |
PF00150(Cellulase) | 3 | ASN A 67TRP A 377ASP A 197 | None | 1.22A | 4a7tA-3axxA:undetectable4a7tF-3axxA:undetectable | 4a7tA-3axxA:15.854a7tF-3axxA:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3djd | FRUCTOSYL AMINE:OXYGENOXIDOREDUCTASE (Aspergillusfumigatus) |
PF01266(DAO) | 3 | ASN A 229TRP A 405ASP A 226 | None | 0.89A | 4a7tA-3djdA:undetectable4a7tF-3djdA:undetectable | 4a7tA-3djdA:17.214a7tF-3djdA:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3efm | FERRIC ALCALIGINSIDEROPHORE RECEPTOR (Bordetellapertussis) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | ASN A 339TRP A 115ASP A 311 | None | 1.21A | 4a7tA-3efmA:undetectable4a7tF-3efmA:undetectable | 4a7tA-3efmA:11.724a7tF-3efmA:11.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3flu | DIHYDRODIPICOLINATESYNTHASE (Neisseriameningitidis) |
PF00701(DHDPS) | 3 | ASN A 34TRP A 30ASP A 216 | GOL A 299 (-3.1A)GOL A 299 (-4.2A)None | 1.09A | 4a7tA-3fluA:undetectable4a7tF-3fluA:undetectable | 4a7tA-3fluA:20.204a7tF-3fluA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fot | 15-O-ACETYLTRANSFERASE (Fusariumsporotrichioides) |
PF07428(Tri3) | 3 | ASN A 46TRP A 98ASP A 52 | None | 1.32A | 4a7tA-3fotA:undetectable4a7tF-3fotA:undetectable | 4a7tA-3fotA:16.634a7tF-3fotA:16.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i1l | HEMAGGLUTININ-ESTERASE PROTEIN (Porcinetorovirus) |
PF02710(Hema_HEFG)PF03996(Hema_esterase) | 3 | ASN A 128TRP A 125ASP A 255 | None | 0.90A | 4a7tA-3i1lA:undetectable4a7tF-3i1lA:undetectable | 4a7tA-3i1lA:18.414a7tF-3i1lA:18.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3if6 | OXA-46 OXACILLINASE (Pseudomonasaeruginosa) |
PF00905(Transpeptidase) | 3 | ASN C 236TRP C 219ASP C 60 | None | 1.24A | 4a7tA-3if6C:undetectable4a7tF-3if6C:undetectable | 4a7tA-3if6C:19.704a7tF-3if6C:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iiw | POLYCOMB PROTEIN EED (Homo sapiens) |
PF00400(WD40) | 3 | ASN A 102TRP A 152ASP A 109 | None | 1.23A | 4a7tA-3iiwA:undetectable4a7tF-3iiwA:undetectable | 4a7tA-3iiwA:17.904a7tF-3iiwA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jcm | U4/U6 SMALL NUCLEARRIBONUCLEOPROTEINPRP4 (Saccharomycescerevisiae) |
PF00400(WD40) | 3 | ASN B 374TRP B 376ASP B 370 | None | 1.18A | 4a7tA-3jcmB:undetectable4a7tF-3jcmB:undetectable | 4a7tA-3jcmB:17.424a7tF-3jcmB:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kom | TRANSKETOLASE (Francisellatularensis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 3 | ASN A 11TRP A 281ASP A 37 | None | 1.12A | 4a7tA-3komA:undetectable4a7tF-3komA:undetectable | 4a7tA-3komA:15.464a7tF-3komA:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lew | SUSD-LIKECARBOHYDRATE BINDINGPROTEIN (Bacteroidesvulgatus) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 3 | ASN A 436TRP A 416ASP A 162 | None | 1.20A | 4a7tA-3lewA:undetectable4a7tF-3lewA:undetectable | 4a7tA-3lewA:14.324a7tF-3lewA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm3 | UNCHARACTERIZEDPROTEIN (Parabacteroidesdistasonis) |
PF12979(DUF3863)PF12980(DUF3864) | 3 | ASN A 364TRP A 367ASP A 236 | None | 1.31A | 4a7tA-3lm3A:undetectable4a7tF-3lm3A:undetectable | 4a7tA-3lm3A:16.114a7tF-3lm3A:16.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oks | 4-AMINOBUTYRATETRANSAMINASE (Mycolicibacteriumsmegmatis) |
PF00202(Aminotran_3) | 3 | ASN A 256TRP A 252ASP A 222 | None | 1.19A | 4a7tA-3oksA:undetectable4a7tF-3oksA:undetectable | 4a7tA-3oksA:16.744a7tF-3oksA:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opy | 6-PHOSPHOFRUCTO-1-KINASE BETA-SUBUNIT (Komagataellapastoris) |
PF00365(PFK) | 3 | ASN B 197TRP B 243ASP B 192 | None | 1.22A | 4a7tA-3opyB:undetectable4a7tF-3opyB:undetectable | 4a7tA-3opyB:11.944a7tF-3opyB:11.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3otn | SUSD SUPERFAMILYPROTEIN (Parabacteroidesdistasonis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 3 | ASN A 475TRP A 476ASP A 460 | None | 1.23A | 4a7tA-3otnA:undetectable4a7tF-3otnA:undetectable | 4a7tA-3otnA:15.494a7tF-3otnA:15.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r7a | PHOSPHOGLYCERATEMUTASE, PUTATIVE (Bacillusanthracis) |
PF00300(His_Phos_1) | 3 | ASN A 96TRP A 32ASP A 140 | None | 1.26A | 4a7tA-3r7aA:undetectable4a7tF-3r7aA:undetectable | 4a7tA-3r7aA:22.864a7tF-3r7aA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rsj | BONT/F (Clostridiumbotulinum) |
PF07951(Toxin_R_bind_C)PF07953(Toxin_R_bind_N) | 3 | ASN A1108TRP A1266ASP A1113 | None | 1.31A | 4a7tA-3rsjA:undetectable4a7tF-3rsjA:undetectable | 4a7tA-3rsjA:14.534a7tF-3rsjA:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3th6 | TRIOSEPHOSPHATEISOMERASE (Rhipicephalusmicroplus) |
PF00121(TIM) | 3 | ASN A 122TRP A 90ASP A 156 | None | 0.68A | 4a7tA-3th6A:undetectable4a7tF-3th6A:undetectable | 4a7tA-3th6A:22.274a7tF-3th6A:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v10 | RHUSIOPATHIAESURFACE PROTEIN B (Erysipelothrixrhusiopathiae) |
PF05737(Collagen_bind) | 3 | ASN A 215TRP A 197ASP A 247 | None | 0.74A | 4a7tA-3v10A:undetectable4a7tF-3v10A:undetectable | 4a7tA-3v10A:20.504a7tF-3v10A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vup | BETA-1,4-MANNANASE (Aplysia kurodai) |
PF00150(Cellulase) | 3 | ASN A 22TRP A 322ASP A 158 | NoneTRS A 401 (-3.8A)None | 1.29A | 4a7tA-3vupA:undetectable4a7tF-3vupA:undetectable | 4a7tA-3vupA:16.764a7tF-3vupA:16.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vzm | ENDO-1,4-BETA-XYLANASE (Bacilluscirculans) |
PF00457(Glyco_hydro_11) | 3 | ASN A 52TRP A 185ASP A 101 | None | 0.88A | 4a7tA-3vzmA:undetectable4a7tF-3vzmA:undetectable | 4a7tA-3vzmA:24.024a7tF-3vzmA:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w0k | BIFUNCTIONALENDOMANNANASE/ENDOGLUCANASE (Caldanaerobiuspolysaccharolyticus) |
PF00150(Cellulase) | 3 | ASN A 7TRP A 291ASP A 133 | NoneTRS A 401 (-3.6A)None | 1.31A | 4a7tA-3w0kA:undetectable4a7tF-3w0kA:undetectable | 4a7tA-3w0kA:18.974a7tF-3w0kA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w6m | 458AA LONGHYPOTHETICALENDO-1,4-BETA-GLUCANASE (Pyrococcushorikoshii) |
PF00150(Cellulase) | 3 | ASN A 67TRP A 377ASP A 197 | None | 1.27A | 4a7tA-3w6mA:undetectable4a7tF-3w6mA:undetectable | 4a7tA-3w6mA:18.104a7tF-3w6mA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wwp | (S)-HYDROXYNITRILELYASE (Baliospermummontanum) |
PF00561(Abhydrolase_1) | 3 | ASN A 221TRP A 217ASP A 111 | None | 1.18A | 4a7tA-3wwpA:undetectable4a7tF-3wwpA:undetectable | 4a7tA-3wwpA:23.084a7tF-3wwpA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyj | LEUCINE-RICHREPEAT-CONTAININGPROTEIN 4CNETRIN-G1 (Homo sapiens) |
PF00053(Laminin_EGF)PF00055(Laminin_N)PF00560(LRR_1)PF07679(I-set)PF13306(LRR_5)PF13855(LRR_8) | 3 | ASN B 84TRP A 154ASP A 225 | None | 1.09A | 4a7tA-3zyjB:undetectable4a7tF-3zyjB:undetectable | 4a7tA-3zyjB:16.714a7tF-3zyjB:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ee9 | ENDOGLUCANASE (unculturedbacterium) |
PF00150(Cellulase) | 3 | ASN A 8TRP A 276ASP A 131 | NoneTRS A 401 (-3.8A)None | 1.26A | 4a7tA-4ee9A:undetectable4a7tF-4ee9A:undetectable | 4a7tA-4ee9A:18.914a7tF-4ee9A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hrt | GLOBIN-2 A CHAINHEMOGLOBIN B CHAIN (Scapharcainaequivalvis) |
PF00042(Globin) | 3 | ASN A 78TRP A 22ASP B 84 | None | 1.18A | 4a7tA-4hrtA:undetectable4a7tF-4hrtA:undetectable | 4a7tA-4hrtA:21.384a7tF-4hrtA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jkm | BETA-GLUCURONIDASE (Clostridiumperfringens) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 3 | ASN A 133TRP A 65ASP A 137 | None | 1.31A | 4a7tA-4jkmA:3.84a7tF-4jkmA:3.2 | 4a7tA-4jkmA:14.384a7tF-4jkmA:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oud | TYROSYL-TRNASYNTHETASE (Escherichiacoli) |
PF00579(tRNA-synt_1b) | 3 | ASN B 126TRP B 129ASP B 41 | ASN B 126 ( 0.6A)TRP B 129 ( 0.5A)ASP B 41 ( 0.6A) | 0.80A | 4a7tA-4oudB:undetectable4a7tF-4oudB:undetectable | 4a7tA-4oudB:18.314a7tF-4oudB:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p27 | VENOM ALLERGEN-LIKE(VAL) 4 PROTEIN (Schistosomamansoni) |
PF00188(CAP) | 3 | ASN A 111TRP A 91ASP A 144 | None | 1.27A | 4a7tA-4p27A:undetectable4a7tF-4p27A:undetectable | 4a7tA-4p27A:19.894a7tF-4p27A:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9c | NOVEL ANTIGENRECEPTOR (Ginglymostomacirratum) |
PF07654(C1-set) | 3 | ASN A 448TRP A 423ASP A 389 | None | 1.16A | 4a7tA-4q9cA:3.84a7tF-4q9cA:3.9 | 4a7tA-4q9cA:19.254a7tF-4q9cA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qdg | PUTATIVE ADHESIN (Bacteroidesthetaiotaomicron) |
PF08842(Mfa2) | 3 | ASN A 213TRP A 156ASP A 302 | None | 1.31A | 4a7tA-4qdgA:undetectable4a7tF-4qdgA:undetectable | 4a7tA-4qdgA:20.074a7tF-4qdgA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tuf | MAJOR EXTRACELLULARENDOGLUCANASE (Xanthomonascampestris) |
PF00150(Cellulase) | 3 | ASN A 48TRP A 337ASP A 178 | None | 1.21A | 4a7tA-4tufA:undetectable4a7tF-4tufA:undetectable | 4a7tA-4tufA:18.294a7tF-4tufA:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uac | CARBOHYDRATE ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN, CUT1 FAMILY(TC 3.A.1.1.-) ([Eubacterium]rectale) |
PF13416(SBP_bac_8) | 3 | ASN A 264TRP A 267ASP A 243 | NoneACR A 501 (-2.7A)None | 1.19A | 4a7tA-4uacA:undetectable4a7tF-4uacA:undetectable | 4a7tA-4uacA:18.394a7tF-4uacA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ued | EUKARYOTICTRANSLATIONINITIATION FACTOR 4E (Homo sapiens) |
PF01652(IF4E) | 3 | ASN A 41TRP A 43ASP A 147 | None | 1.27A | 4a7tA-4uedA:undetectable4a7tF-4uedA:undetectable | 4a7tA-4uedA:20.774a7tF-4uedA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uis | GAMMA-SECRETASE (Homo sapiens) |
PF05450(Nicastrin) | 3 | ASN A 290TRP A 289ASP A 548 | None | 0.91A | 4a7tA-4uisA:undetectable4a7tF-4uisA:undetectable | 4a7tA-4uisA:13.634a7tF-4uisA:13.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uzj | NOTUM (Drosophilamelanogaster) |
PF03283(PAE) | 3 | ASN A 175TRP A 119ASP A 84 | None | 1.12A | 4a7tA-4uzjA:undetectable4a7tF-4uzjA:undetectable | 4a7tA-4uzjA:15.894a7tF-4uzjA:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wu0 | SIMILAR TO YTER(BACILUS SUBTILIS) (Clostridiumacetobutylicum) |
PF07470(Glyco_hydro_88) | 3 | ASN A 79TRP A 23ASP A 32 | None | 1.18A | 4a7tA-4wu0A:undetectable4a7tF-4wu0A:undetectable | 4a7tA-4wu0A:17.654a7tF-4wu0A:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xeu | TRANSKETOLASE (Pseudomonasaeruginosa) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 3 | ASN A 9TRP A 278ASP A 35 | None | 1.14A | 4a7tA-4xeuA:undetectable4a7tF-4xeuA:undetectable | 4a7tA-4xeuA:13.444a7tF-4xeuA:13.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhc | ALPHA-L-RHAMNOSIDASE (Klebsiellaoxytoca) |
PF17389(Bac_rhamnosid6H) | 3 | ASN A 267TRP A 226ASP A 278 | NoneRAM A 900 (-3.8A)None | 1.09A | 4a7tA-4xhcA:undetectable4a7tF-4xhcA:undetectable | 4a7tA-4xhcA:16.564a7tF-4xhcA:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xru | PNKP1 (Capnocytophagagingivalis) |
PF13671(AAA_33) | 3 | ASN A 81TRP A 38ASP A 106 | None | 1.23A | 4a7tA-4xruA:undetectable4a7tF-4xruA:undetectable | 4a7tA-4xruA:19.684a7tF-4xruA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a30 | MITOCHONDRIALPROTEIN (Gallus gallus) |
PF03828(PAP_assoc) | 3 | ASN A 453TRP A 471ASP A 394 | None | 1.23A | 4a7tA-5a30A:undetectable4a7tF-5a30A:undetectable | 4a7tA-5a30A:15.564a7tF-5a30A:15.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aby | EUKARYOTICTRANSLATIONINITIATION FACTOR4E-3 (Caenorhabditiselegans) |
PF01652(IF4E) | 3 | ASN A 36TRP A 38ASP A 145 | None | 1.21A | 4a7tA-5abyA:undetectable4a7tF-5abyA:undetectable | 4a7tA-5abyA:20.304a7tF-5abyA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aw4 | NA, K-ATPASE ALPHASUBUNIT (Squalusacanthias) |
PF00122(E1-E2_ATPase)PF00689(Cation_ATPase_C)PF00690(Cation_ATPase_N)PF13246(Cation_ATPase) | 3 | ASN A 395TRP A 392ASP A 533 | None | 1.28A | 4a7tA-5aw4A:undetectable4a7tF-5aw4A:undetectable | 4a7tA-5aw4A:9.864a7tF-5aw4A:9.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ei3 | EUKARYOTICTRANSLATIONINITIATION FACTOR 4E (Homo sapiens) |
PF01652(IF4E) | 3 | ASN A 41TRP A 43ASP A 147 | None | 1.27A | 4a7tA-5ei3A:undetectable4a7tF-5ei3A:undetectable | 4a7tA-5ei3A:22.274a7tF-5ei3A:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7h | T-CELLIMMUNOGLOBULIN ANDMUCINDOMAIN-CONTAININGPROTEIN 4 (Homo sapiens) |
no annotation | 3 | ASN B 29TRP B 24ASP B 101 | NoneNone CA B 201 ( 3.1A) | 1.28A | 4a7tA-5f7hB:undetectable4a7tF-5f7hB:undetectable | 4a7tA-5f7hB:22.674a7tF-5f7hB:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fbz | ENZYME SUBTILASESUBHAL FROM BACILLUSHALMAPALUS (Bacillushalmapalus) |
PF00082(Peptidase_S8)PF04151(PPC) | 3 | ASN A 397TRP A 350ASP A 218 | None | 1.31A | 4a7tA-5fbzA:undetectable4a7tF-5fbzA:undetectable | 4a7tA-5fbzA:17.664a7tF-5fbzA:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hvn | 3-DEHYDROQUINATESYNTHASE (Francisellatularensis) |
PF01761(DHQ_synthase) | 3 | ASN A 202TRP A 198ASP A 210 | None | 1.30A | 4a7tA-5hvnA:undetectable4a7tF-5hvnA:undetectable | 4a7tA-5hvnA:16.394a7tF-5hvnA:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6s | ENDOGLUCANASE (Talaromycesverruculosus) |
PF00150(Cellulase) | 3 | ASN A 19TRP A 282ASP A 138 | None | 1.29A | 4a7tA-5i6sA:undetectable4a7tF-5i6sA:undetectable | 4a7tA-5i6sA:20.684a7tF-5i6sA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i77 | ENDO-BETA-1,4-GLUCANASE (Aspergillusniger) |
PF00150(Cellulase) | 3 | ASN A 38TRP A 300ASP A 156 | NonePEG A 403 ( 4.1A)None | 1.27A | 4a7tA-5i77A:undetectable4a7tF-5i77A:undetectable | 4a7tA-5i77A:20.004a7tF-5i77A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihx | TYROSINE--TRNALIGASE,MITOCHONDRIAL (Aspergillusnidulans) |
PF00579(tRNA-synt_1b) | 3 | ASN A 227TRP A 230ASP A 131 | TYR A 501 ( 4.6A)NoneTYR A 501 (-2.9A) | 0.87A | 4a7tA-5ihxA:undetectable4a7tF-5ihxA:undetectable | 4a7tA-5ihxA:17.944a7tF-5ihxA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ijx | TYROSINE--TRNALIGASE,MITOCHONDRIAL (Coccidioidesposadasii) |
PF00579(tRNA-synt_1b) | 3 | ASN A 214TRP A 217ASP A 118 | TYR A 501 ( 4.4A)NoneTYR A 501 (-2.9A) | 0.81A | 4a7tA-5ijxA:undetectable4a7tF-5ijxA:undetectable | 4a7tA-5ijxA:17.554a7tF-5ijxA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irr | SEPTIN-LIKE PROTEIN (Chlamydomonasreinhardtii) |
PF00735(Septin) | 3 | ASN A 204TRP A 387ASP A 225 | None | 0.47A | 4a7tA-5irrA:undetectable4a7tF-5irrA:undetectable | 4a7tA-5irrA:18.364a7tF-5irrA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j6s | ENDOPLASMICRETICULUMAMINOPEPTIDASE 2 (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 3 | ASN A 948TRP A 944ASP A 678 | None | 0.95A | 4a7tA-5j6sA:undetectable4a7tF-5j6sA:undetectable | 4a7tA-5j6sA:11.054a7tF-5j6sA:11.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jp6 | PUTATIVEPOLYSACCHARIDEDEACETYLASE (Bdellovibriobacteriovorus) |
PF01522(Polysacc_deac_1) | 3 | ASN A 37TRP A 46ASP A 89 | None | 1.11A | 4a7tA-5jp6A:undetectable4a7tF-5jp6A:undetectable | 4a7tA-5jp6A:19.024a7tF-5jp6A:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m6q | UNCHARACTERIZEDPROTEIN (Kutzneriaalbida) |
PF09017(Transglut_prok) | 3 | ASN A 53TRP A 178ASP A 226 | None | 1.23A | 4a7tA-5m6qA:undetectable4a7tF-5m6qA:undetectable | 4a7tA-5m6qA:20.184a7tF-5m6qA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n6u | BETA-MANNOSIDASE (Dictyoglomusthermophilum) |
PF00703(Glyco_hydro_2)PF02837(Glyco_hydro_2_N) | 3 | ASN A 476TRP A 428ASP A 501 | None | 1.27A | 4a7tA-5n6uA:5.64a7tF-5n6uA:5.9 | 4a7tA-5n6uA:10.674a7tF-5n6uA:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t47 | EUKARYOTICTRANSLATIONINITIATION FACTOR 4E (Drosophilamelanogaster) |
PF01652(IF4E) | 3 | ASN A 74TRP A 76ASP A 178 | None | 1.22A | 4a7tA-5t47A:undetectable4a7tF-5t47A:undetectable | 4a7tA-5t47A:22.164a7tF-5t47A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v1w | GLYCOSIDE HYDROLASE (Bacillushalodurans) |
PF03639(Glyco_hydro_81) | 3 | ASN A 440TRP A 426ASP A 45 | None | 0.92A | 4a7tA-5v1wA:undetectable4a7tF-5v1wA:undetectable | 4a7tA-5v1wA:11.824a7tF-5v1wA:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v1w | GLYCOSIDE HYDROLASE (Bacillushalodurans) |
PF03639(Glyco_hydro_81) | 3 | ASN A 540TRP A 606ASP A 466 | BGC A 801 (-3.1A)NoneBGC A 801 ( 2.7A) | 1.10A | 4a7tA-5v1wA:undetectable4a7tF-5v1wA:undetectable | 4a7tA-5v1wA:11.824a7tF-5v1wA:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wh8 | PUTATIVECARBOHYDRATE-ACTIVEENZYME (unculturedorganism) |
no annotation | 3 | ASN A 198TRP A 234ASP A 201 | None | 1.30A | 4a7tA-5wh8A:undetectable4a7tF-5wh8A:undetectable | 4a7tA-5wh8A:19.874a7tF-5wh8A:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x62 | CARNOSINEN-METHYLTRANSFERASE (Saccharomycescerevisiae) |
PF07942(N2227) | 3 | ASN A 302TRP A 300ASP A 278 | None | 1.31A | 4a7tA-5x62A:undetectable4a7tF-5x62A:undetectable | 4a7tA-5x62A:18.284a7tF-5x62A:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xtb | NADH DEHYDROGENASE[UBIQUINONE]IRON-SULFUR PROTEIN4, MITOCHONDRIALNADH-UBIQUINONEOXIDOREDUCTASE 75KDA SUBUNIT,MITOCHONDRIAL (Homo sapiens) |
PF00384(Molybdopterin)PF04800(ETC_C1_NDUFA4)PF09326(NADH_dhqG_C)PF10588(NADH-G_4Fe-4S_3)PF13510(Fer2_4) | 3 | ASN L 167TRP L 166ASP M 426 | None | 0.88A | 4a7tA-5xtbL:undetectable4a7tF-5xtbL:undetectable | 4a7tA-5xtbL:21.384a7tF-5xtbL:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yf0 | - (-) |
no annotation | 3 | ASN A 340TRP A 338ASP A 316 | None | 1.27A | 4a7tA-5yf0A:undetectable4a7tF-5yf0A:undetectable | 4a7tA-5yf0A:undetectable4a7tF-5yf0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yq0 | COFJ (Escherichiacoli) |
no annotation | 3 | ASN A 240TRP A 244ASP A 72 | None | 0.94A | 4a7tA-5yq0A:undetectable4a7tF-5yq0A:1.4 | 4a7tA-5yq0A:17.294a7tF-5yq0A:17.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b2y | SOLUTE-BINDINGPERIPLASMIC PROTEINOF IRON/SIDEROPHOREABC TRANSPORTER (Yersinia pestis) |
no annotation | 3 | ASN A 294TRP A 292ASP A 49 | None | 1.11A | 4a7tA-6b2yA:undetectable4a7tF-6b2yA:undetectable | 4a7tA-6b2yA:18.734a7tF-6b2yA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ba5 | INACTIVETYROSINE-PROTEINKINASE TRANSMEMBRANERECEPTOR ROR1VARIABLE DOMAINHEAVY CHAIN,ANTIBODY R11VARIABLE DOMAIN OFLIGHT CHAIN,ANTIBODY R11 (Homo sapiens) |
no annotation | 3 | ASN A 95TRP B 57ASP M 378 | None | 1.27A | 4a7tA-6ba5A:undetectable4a7tF-6ba5A:undetectable | 4a7tA-6ba5A:22.314a7tF-6ba5A:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bo6 | - (-) |
no annotation | 3 | ASN A 133TRP A 65ASP A 137 | None | 1.27A | 4a7tA-6bo6A:undetectable4a7tF-6bo6A:undetectable | 4a7tA-6bo6A:undetectable4a7tF-6bo6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cwo | RIBONUCLEOTIDEREDUCTASE (Flavobacteriumjohnsoniae) |
no annotation | 3 | ASN A 186TRP A 190ASP A 40 | None | 1.30A | 4a7tA-6cwoA:undetectable4a7tF-6cwoA:undetectable | 4a7tA-6cwoA:15.694a7tF-6cwoA:15.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cwp | RIBONUCLEOTIDEREDUCTASE (Flavobacteriumjohnsoniae) |
no annotation | 3 | ASN A 186TRP A 190ASP A 40 | None | 1.26A | 4a7tA-6cwpA:undetectable4a7tF-6cwpA:undetectable | 4a7tA-6cwpA:24.754a7tF-6cwpA:24.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f0k | FE-S-CLUSTER-CONTAINING HYDROGENASEPOLYSULPHIDEREDUCTASE NRFD (Rhodothermusmarinus) |
no annotation | 3 | ASN B 905TRP C 82ASP C 406 | None | 0.85A | 4a7tA-6f0kB:undetectable4a7tF-6f0kB:undetectable | 4a7tA-6f0kB:20.654a7tF-6f0kB:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fml | LES2RUVB-LIKE HELICASE (Chaetomiumthermophilum) |
no annotation | 3 | ASN H 452TRP H 450ASP D 190 | None | 1.22A | 4a7tA-6fmlH:undetectable4a7tF-6fmlH:undetectable | 4a7tA-6fmlH:17.094a7tF-6fmlH:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gh2 | LAMINARIBIOSEPHOSPHORYLASE (Paenibacillussp. YM1) |
no annotation | 3 | ASN A 408TRP A 373ASP A 405 | None | 0.98A | 4a7tA-6gh2A:1.34a7tF-6gh2A:undetectable | 4a7tA-6gh2A:24.164a7tF-6gh2A:24.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6grw | - (-) |
no annotation | 3 | ASN A 140TRP A 184ASP A 203 | None | 0.94A | 4a7tA-6grwA:undetectable4a7tF-6grwA:undetectable | 4a7tA-6grwA:undetectable4a7tF-6grwA:undetectable |