SIMILAR PATTERNS OF AMINO ACIDS FOR 4A6N_A_T1CA392_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dbj | IGG1-KAPPA DB3 FAB(HEAVY CHAIN) (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | GLN H 6PHE H 91ASN H 35GLY H 104ALA H 40 | NoneNoneAE2 H 229 (-2.9A)NoneNone | 1.20A | 4a6nA-1dbjH:undetectable | 4a6nA-1dbjH:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f76 | DIHYDROOROTATEDEHYDROGENASE(QUINONE) (Escherichiacoli) |
PF01180(DHO_dh) | 5 | GLY A 94ALA A 62GLY A 63GLU A 83ASN A 139 | NoneFMN A1337 (-3.7A)FMN A1337 (-3.1A)NoneFMN A1337 (-3.3A) | 1.27A | 4a6nA-1f76A:undetectable | 4a6nA-1f76A:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h0h | FORMATEDEHYDROGENASESUBUNIT ALPHA (Desulfovibriogigas) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 5 | ASN A 198GLY A 408GLY A 864GLU A 548ASN A 518 | MGD A1002 (-3.4A)MGD A1002 (-3.2A)NoneNoneNone | 1.27A | 4a6nA-1h0hA:undetectable | 4a6nA-1h0hA:17.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i2m | REGULATOR OFCHROMOSOMECONDENSATION 1 (Homo sapiens) |
PF00415(RCC1) | 5 | PHE B 91ASN B 94GLY B 113ALA B 74GLY B 75 | None | 1.26A | 4a6nA-1i2mB:undetectable | 4a6nA-1i2mB:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o50 | CBSDOMAIN-CONTAININGPREDICTED PROTEINTM0935 (Thermotogamaritima) |
PF00571(CBS) | 5 | ASN A 45GLY A 124PRO A 118GLU A 134MET A 98 | None | 1.27A | 4a6nA-1o50A:undetectable | 4a6nA-1o50A:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pvd | PYRUVATEDECARBOXYLASE (Saccharomycescerevisiae) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ARG A 224GLY A 250ALA A 287GLY A 286GLU A 308 | None | 1.24A | 4a6nA-1pvdA:0.9 | 4a6nA-1pvdA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1si8 | CATALASE (Enterococcusfaecalis) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | PHE A 111GLY A 126ALA A 60GLY A 59MET A 295 | NoneHEM A 501 (-3.8A)NoneNoneNone | 1.20A | 4a6nA-1si8A:undetectable | 4a6nA-1si8A:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ulv | GLUCODEXTRANASE (Arthrobacterglobiformis) |
PF00723(Glyco_hydro_15)PF09136(Glucodextran_B)PF09137(Glucodextran_N)PF09985(Glucodextran_C) | 5 | GLN A 629GLY A 574PRO A 312ALA A 317GLY A 314 | None | 1.27A | 4a6nA-1ulvA:undetectable | 4a6nA-1ulvA:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uuo | DIHYDROOROTATEDEHYDROGENASE (Rattus rattus) |
PF01180(DHO_dh) | 5 | GLY A 128ALA A 96GLY A 97GLU A 117ASN A 181 | NoneFMN A1398 (-3.7A)FMN A1398 (-3.0A)NoneFMN A1398 (-3.2A) | 1.24A | 4a6nA-1uuoA:undetectable | 4a6nA-1uuoA:24.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wyt | GLYCINEDEHYDROGENASE(DECARBOXYLATING)SUBUNIT 1GLYCINEDEHYDROGENASESUBUNIT 2(P-PROTEIN) (Thermusthermophilus) |
PF02347(GDC-P) | 5 | ARG A 285GLY A 270ALA B 133GLY B 132GLU B 136 | None | 1.08A | 4a6nA-1wytA:undetectable | 4a6nA-1wytA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e9q | 11S GLOBULIN SUBUNITBETA (Cucurbitamaxima) |
PF00190(Cupin_1) | 5 | GLN A 91GLY A 92ALA A 45GLY A 46GLU A 44 | None | 1.20A | 4a6nA-2e9qA:undetectable | 4a6nA-2e9qA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fhx | SPM-1 (Pseudomonasaeruginosa) |
PF00753(Lactamase_B) | 5 | PHE B 61PRO B 86GLY B 123GLU B 126ASN B 89 | None | 1.31A | 4a6nA-2fhxB:undetectable | 4a6nA-2fhxB:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h1n | OLIGOENDOPEPTIDASE F (Geobacillusstearothermophilus) |
PF01432(Peptidase_M3) | 5 | GLY A 472ALA A 433GLU A 436ASN A 437MET A 440 | None | 1.28A | 4a6nA-2h1nA:undetectable | 4a6nA-2h1nA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j2m | CATALASE (Exiguobacteriumoxidotolerans) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | PHE A 113GLY A 128ALA A 62GLY A 61MET A 297 | NoneHEM A 501 (-3.7A)NoneNoneNone | 1.12A | 4a6nA-2j2mA:undetectable | 4a6nA-2j2mA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ldk | UNCHARACTERIZEDPROTEIN (Paenarthrobacteraurescens) |
PF08327(AHSA1) | 5 | GLN A 134PHE A 94GLY A 106GLY A 142GLU A 149 | None | 1.22A | 4a6nA-2ldkA:undetectable | 4a6nA-2ldkA:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nrx | UVRABC SYSTEMPROTEIN C (Thermotogamaritima) |
PF08459(UvrC_HhH_N) | 5 | PHE A 427GLY A 365ALA A 455GLY A 431GLU A 458 | NoneNoneNoneSO4 A 903 (-3.5A)None | 0.91A | 4a6nA-2nrxA:undetectable | 4a6nA-2nrxA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2tpt | THYMIDINEPHOSPHORYLASE (Escherichiacoli) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 5 | GLY A 206ALA A 247GLY A 91GLU A 258ASN A 269 | None | 1.28A | 4a6nA-2tptA:2.8 | 4a6nA-2tptA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uvd | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Bacillusanthracis) |
PF13561(adh_short_C2) | 5 | GLN A 82PHE A 80GLY A 81ALA A 25GLY A 28 | None | 1.22A | 4a6nA-2uvdA:6.6 | 4a6nA-2uvdA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdc | GLUTAMATE SYNTHASE[NADPH] SMALL CHAIN (Azospirillumbrasilense) |
PF07992(Pyr_redox_2)PF14691(Fer4_20) | 5 | PRO G 157ALA G 161GLY G 159GLU G 165ASN G 89 | FAD G 484 (-3.6A)NoneNoneNoneNone | 1.22A | 4a6nA-2vdcG:5.4 | 4a6nA-2vdcG:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wk2 | CHITINASE A (Serratiamarcescens) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 5 | PHE A 316ASN A 323GLY A 319GLY A 273MET A 388 | NoneNoneNoneNoneNGT A1565 (-3.7A) | 1.20A | 4a6nA-2wk2A:undetectable | 4a6nA-2wk2A:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wsb | GALACTITOLDEHYDROGENASE (Rhodobactersphaeroides) |
PF13561(adh_short_C2) | 5 | ARG A 29GLY A 56ALA A 47GLY A 20GLU A 44 | NoneNoneNAD A 500 ( 4.9A)NAD A 500 ( 3.8A)NAD A 500 ( 4.1A) | 1.23A | 4a6nA-2wsbA:4.7 | 4a6nA-2wsbA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xf2 | CATALASE (Penicilliumjanthinellum) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | PHE A 121GLY A 136ALA A 70GLY A 69MET A 309 | NoneHDD A 690 (-3.9A)NoneNoneNone | 1.19A | 4a6nA-2xf2A:3.7 | 4a6nA-2xf2A:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ada | SARCOSINE OXIDASEBETA SUBUNIT (Corynebacteriumsp. U-96) |
PF01266(DAO) | 5 | GLN B 294GLY B 326ALA B 224GLY B 27ASN B 349 | NoneFAD B 1 (-3.5A)NoneFAD B 1 (-3.3A)None | 1.32A | 4a6nA-3adaB:14.8 | 4a6nA-3adaB:24.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3asi | NEUREXIN-1-ALPHA (Bos taurus) |
PF02210(Laminin_G_2) | 5 | GLN A1064PHE A1068GLY A1067GLY A1059ASN A1083 | None | 1.22A | 4a6nA-3asiA:undetectable | 4a6nA-3asiA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egw | RESPIRATORY NITRATEREDUCTASE 1 ALPHACHAINRESPIRATORY NITRATEREDUCTASE 1 BETACHAIN (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF13247(Fer4_11)PF14710(Nitr_red_alph_N)PF14711(Nitr_red_bet_C) | 5 | GLN A1152PHE B 176GLY B 49GLU B 57ASN B 160 | None | 1.28A | 4a6nA-3egwA:2.5 | 4a6nA-3egwA:15.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fk5 | 3-OXOACYL-SYNTHASEIII (Xanthomonasoryzae) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | PHE A 126ASN A 121GLY A 129ALA A 187GLY A 150 | None | 1.27A | 4a6nA-3fk5A:undetectable | 4a6nA-3fk5A:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3grh | ACYL-COA THIOESTERHYDROLASE YBGC (Escherichiacoli) |
PF01095(Pectinesterase) | 5 | ARG A 14PHE A 340GLY A 311ALA A 335GLY A 388 | None | 1.08A | 4a6nA-3grhA:undetectable | 4a6nA-3grhA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihv | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 5 | GLY A 489PRO A 390ALA A 322GLY A 307ASN A 323 | CL A 1 (-3.7A)NoneNoneNoneNone | 1.24A | 4a6nA-3ihvA:undetectable | 4a6nA-3ihvA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j31 | A223 PENTON BASE (Sulfolobusturretedicosahedralvirus 1) |
no annotation | 5 | GLY Q 53PRO Q 157ALA Q 201GLY Q 202ASN Q 159 | None | 1.30A | 4a6nA-3j31Q:undetectable | 4a6nA-3j31Q:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9u | V-TYPE PROTON ATPASECATALYTIC SUBUNIT A (Saccharomycescerevisiae) |
no annotation | 5 | PRO C 84ALA C 26GLY C 82GLU C 38ASN C 39 | None | 1.25A | 4a6nA-3j9uC:undetectable | 4a6nA-3j9uC:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3koy | D-ORNITHINEAMINOMUTASE ECOMPONENT (Acetoanaerobiumsticklandii) |
PF02310(B12-binding)PF09043(Lys-AminoMut_A)PF16554(OAM_dimer) | 5 | GLY A 166ALA A 216GLY A 180ASN A 261MET A 257 | None | 1.34A | 4a6nA-3koyA:undetectable | 4a6nA-3koyA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpp | SUCRASE-ISOMALTASE (Homo sapiens) |
PF00088(Trefoil)PF01055(Glyco_hydro_31)PF16863(NtCtMGAM_N) | 5 | GLN A 245GLY A 243ALA A 599GLY A 598ASN A 572 | None | 1.13A | 4a6nA-3lppA:undetectable | 4a6nA-3lppA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m1h | LYSINE SPECIFICCYSTEINE PROTEASE (Porphyromonasgingivalis) |
PF07675(Cleaved_Adhesin) | 5 | PHE A1584ASN A1490GLY A1585ALA A1536ASN A1537 | None CA A2001 (-2.9A)NoneNoneNone | 1.34A | 4a6nA-3m1hA:undetectable | 4a6nA-3m1hA:18.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p9u | TETX2 PROTEIN (Bacteroidesthetaiotaomicron) |
PF01494(FAD_binding_3) | 7 | GLN A 192ARG A 213ASN A 226ALA A 320GLY A 321ASN A 371MET A 375 | FAD A 401 (-3.4A)SO4 A 1 (-4.5A)SO4 A 1 (-4.5A)NoneNoneNoneNone | 0.82A | 4a6nA-3p9uA:58.3 | 4a6nA-3p9uA:94.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p9u | TETX2 PROTEIN (Bacteroidesthetaiotaomicron) |
PF01494(FAD_binding_3) | 8 | GLN A 192ARG A 213ASN A 226GLY A 236PRO A 318ALA A 320GLY A 321MET A 375 | FAD A 401 (-3.4A)SO4 A 1 (-4.5A)SO4 A 1 (-4.5A)NoneFAD A 401 (-4.4A)NoneNoneNone | 0.60A | 4a6nA-3p9uA:58.3 | 4a6nA-3p9uA:94.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pea | ENOYL-COAHYDRATASE/ISOMERASEFAMILY PROTEIN (Bacillusanthracis) |
PF00378(ECH_1) | 5 | PHE A 235GLY A 232ALA A 245GLY A 243GLU A 249 | None | 1.29A | 4a6nA-3peaA:undetectable | 4a6nA-3peaA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3poy | NEUREXIN-1-ALPHA (Bos taurus) |
PF00008(EGF)PF02210(Laminin_G_2) | 5 | GLN A1124PHE A1128GLY A1127GLY A1119ASN A1143 | None | 1.20A | 4a6nA-3poyA:undetectable | 4a6nA-3poyA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pvo | C-REACTIVE PROTEIN (Homo sapiens) |
PF00354(Pentaxin) | 5 | GLN A 139PHE A 142GLY A 143ALA A 129GLY A 128 | None | 0.96A | 4a6nA-3pvoA:undetectable | 4a6nA-3pvoA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3q | ALKALINE PHOSPHATASE (Sphingomonassp. BSAR-1) |
PF01663(Phosphodiest) | 5 | PHE A 260GLY A 259PRO A 192GLY A 190ASN A 211 | None | 1.19A | 4a6nA-3q3qA:undetectable | 4a6nA-3q3qA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qdf | 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATEISOMERASE (Mycobacteriummarinum) |
PF01557(FAA_hydrolase)PF10370(DUF2437) | 5 | PHE A 116ASN A 257GLY A 118ALA A 195GLY A 194 | None | 1.01A | 4a6nA-3qdfA:undetectable | 4a6nA-3qdfA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t4j | HISTIDINE KINASE 4 (Arabidopsisthaliana) |
PF03924(CHASE) | 5 | PHE A 153ASN A 158GLY A 379ALA A 322GLY A 321 | NoneNoneNoneZIP A 400 (-3.5A)None | 1.15A | 4a6nA-3t4jA:undetectable | 4a6nA-3t4jA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uiw | GLUTAREDOXIN 2 (Danio rerio) |
PF00462(Glutaredoxin) | 5 | GLN A 89PHE A 85GLY A 88ALA A 73GLY A 77 | None | 1.34A | 4a6nA-3uiwA:undetectable | 4a6nA-3uiwA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w5f | BETA-GALACTOSIDASE (Solanumlycopersicum) |
PF01301(Glyco_hydro_35) | 5 | GLY A 303PRO A 519ALA A 496GLY A 497ASN A 556 | NoneNoneEPE A 805 ( 4.4A)NoneEPE A 805 (-3.4A) | 1.21A | 4a6nA-3w5fA:undetectable | 4a6nA-3w5fA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wvo | CRISPR-ASSOCIATEDPROTEIN, CSE1 FAMILY (Thermobifidafusca) |
PF09481(CRISPR_Cse1) | 5 | GLN A 316ARG A 357ASN A 224ALA A 335GLY A 339 | None | 1.27A | 4a6nA-3wvoA:undetectable | 4a6nA-3wvoA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aef | NEOPULLULANASE(ALPHA-AMYLASE II) (Pyrococcusfuriosus) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16561(AMPK1_CBM) | 5 | PHE A 122ASN A 587GLY A 123ALA A 490GLY A 488 | None | 1.25A | 4a6nA-4aefA:undetectable | 4a6nA-4aefA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ayz | HEME-BINDING PROTEIN2 (Homo sapiens) |
PF04832(SOUL) | 5 | ASN A 70GLY A 65ALA A 177GLY A 178GLU A 191 | None | 1.14A | 4a6nA-4ayzA:undetectable | 4a6nA-4ayzA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7v | TRANSKETOLASE (Lactobacillussalivarius) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | ASN A 256GLY A 264PRO A 32ALA A 35GLY A 34 | None | 1.31A | 4a6nA-4c7vA:undetectable | 4a6nA-4c7vA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cab | CATALASE (Deinococcusradiodurans) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | PHE A 143GLY A 158ALA A 87GLY A 86MET A 327 | NoneHEM A 537 (-4.0A)NoneNoneNone | 1.25A | 4a6nA-4cabA:undetectable | 4a6nA-4cabA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ccl | 50S RIBOSOMALPROTEIN L16 ARGININEHYDROXYLASE (Escherichiacoli) |
PF08007(Cupin_4) | 5 | PHE A 28ASN A 30GLY A 176PRO A 34ALA A 95 | None | 1.33A | 4a6nA-4cclA:undetectable | 4a6nA-4cclA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cx9 | CYTOCHROME C, CLASSII (Shewanellafrigidimarina) |
PF01322(Cytochrom_C_2) | 5 | PHE A 23ASN A 47GLY A 24ALA A 110ASN A 113 | HEC A1129 ( 4.0A)NoneNoneNoneNone | 1.22A | 4a6nA-4cx9A:undetectable | 4a6nA-4cx9A:15.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eg2 | CYTIDINE DEAMINASE (Vibrio cholerae) |
PF00383(dCMP_cyt_deam_1)PF08211(dCMP_cyt_deam_2) | 5 | ARG A 4GLY A 252ALA A 103GLY A 74GLU A 104 | NoneNoneURI A 302 (-3.8A)NoneURI A 302 (-3.0A) | 1.17A | 4a6nA-4eg2A:undetectable | 4a6nA-4eg2A:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4flx | DNA POLYMERASE 1 (Pyrococcusabyssi) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | GLN A 665PHE A 152GLY A 696ALA A 215GLY A 211 | GLN A 665 ( 0.6A)PHE A 152 ( 1.3A)GLY A 696 ( 0.0A)ALA A 215 ( 0.0A)GLY A 211 ( 0.0A) | 1.24A | 4a6nA-4flxA:undetectable | 4a6nA-4flxA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fvv | NEUROTOXIN (Clostridiumbotulinum) |
PF07951(Toxin_R_bind_C)PF07953(Toxin_R_bind_N) | 5 | ARG A1132ASN A1135GLY A 999ALA A1282GLU A1107 | None | 1.27A | 4a6nA-4fvvA:undetectable | 4a6nA-4fvvA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i62 | AMINO ACID ABCTRANSPORTER,PERIPLASMIC AMINOACID-BINDINGPROTEIN, PUTATIVE (Streptococcuspneumoniae) |
PF00497(SBP_bac_3) | 5 | PHE A 48GLY A 107PRO A 199ALA A 201GLY A 203 | ARG A 301 (-3.4A)ARG A 301 (-4.7A)NoneNoneNone | 1.25A | 4a6nA-4i62A:undetectable | 4a6nA-4i62A:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jc8 | HOPS COMPONENT VPS33 (Chaetomiumthermophilum) |
PF00995(Sec1) | 5 | PHE A 157ASN A 154PRO A 245GLY A 643MET A 465 | None | 1.20A | 4a6nA-4jc8A:undetectable | 4a6nA-4jc8A:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcl | CYCLOMALTODEXTRINGLUCANOTRANSFERASE (Paenibacillusmacerans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 5 | GLY A 99PRO A 143ALA A 198GLY A 155ASN A 193 | NoneEDO A 720 ( 4.9A)NoneNoneNone | 1.30A | 4a6nA-4jclA:undetectable | 4a6nA-4jclA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k1c | VACUOLAR CALCIUM IONTRANSPORTER (Saccharomycescerevisiae) |
PF01699(Na_Ca_ex) | 5 | GLN A 152GLY A 145ALA A 322GLY A 320ASN A 133 | None | 1.11A | 4a6nA-4k1cA:undetectable | 4a6nA-4k1cA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k2n | ENOYL-COAHYDRATASE/CARNITHINERACEMASE (Magnetospirillummagneticum) |
PF00378(ECH_1) | 5 | ASN A 25GLY A 112ALA A 36GLY A 34GLU A 40 | None | 1.35A | 4a6nA-4k2nA:undetectable | 4a6nA-4k2nA:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k2n | ENOYL-COAHYDRATASE/CARNITHINERACEMASE (Magnetospirillummagneticum) |
PF00378(ECH_1) | 5 | ASN A 25GLY A 113ALA A 36GLY A 34GLU A 40 | None | 1.33A | 4a6nA-4k2nA:undetectable | 4a6nA-4k2nA:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lk5 | ENOYL-COA HYDRATASE (Mycobacteriumavium) |
PF00378(ECH_1) | 5 | ASN A 35GLY A 73ALA A 46GLY A 44GLU A 50 | None | 1.31A | 4a6nA-4lk5A:undetectable | 4a6nA-4lk5A:25.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o9x | TCDB2, TCCC3 (Photorhabdusluminescens) |
PF03534(SpvB)PF12255(TcdB_toxin_midC)PF12256(TcdB_toxin_midN) | 5 | GLY A 705ALA A 97GLY A 98ASN A 94MET A 70 | None | 0.96A | 4a6nA-4o9xA:undetectable | 4a6nA-4o9xA:11.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qor | CATALASE (Bacilluspumilus) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | PHE A 114GLY A 129ALA A 63GLY A 62MET A 298 | NoneHEM A 501 ( 3.8A)NoneNoneNone | 1.31A | 4a6nA-4qorA:undetectable | 4a6nA-4qorA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4um8 | INTEGRIN ALPHA-VINTEGRIN BETA-6 (Homo sapiens) |
PF00362(Integrin_beta)PF01839(FG-GAP)PF08441(Integrin_alpha2)PF17205(PSI_integrin) | 5 | PHE B 259GLY B 260PRO A 244ALA A 246GLY A 251 | None | 1.30A | 4a6nA-4um8B:undetectable | 4a6nA-4um8B:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ye5 | PEPTIDOGLYCANSYNTHETASEPENICILLIN-BINDINGPROTEIN 3 (Bifidobacteriumadolescentis) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 5 | GLN A 226ASN A 169GLY A 172ALA A 122GLY A 121 | None | 1.06A | 4a6nA-4ye5A:undetectable | 4a6nA-4ye5A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yyc | PUTATIVETRIMETHYLAMINEMETHYLTRANSFERASE (Sinorhizobiummeliloti) |
PF06253(MTTB) | 5 | GLN A 267PHE A 228ASN A 235GLU A 124ASN A 122 | None | 1.34A | 4a6nA-4yycA:undetectable | 4a6nA-4yycA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z37 | PUTATIVE MIXEDPOLYKETIDESYNTHASE/NON-RIBOSOMAL PEPTIDESYNTHETASE (Brevibacillusbrevis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | GLN A2877GLY A2872ALA A2860GLY A2899GLU A2825 | None | 1.34A | 4a6nA-4z37A:undetectable | 4a6nA-4z37A:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3j | NMDA GLUTAMATERECEPTOR SUBUNIT (Xenopus laevis) |
PF01094(ANF_receptor) | 5 | PHE A 137GLY A 365PRO A 117ALA A 111GLY A 112 | None | 1.35A | 4a6nA-5b3jA:3.6 | 4a6nA-5b3jA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cer | BD0816 (Bdellovibriobacteriovorus) |
PF02113(Peptidase_S13) | 5 | PHE A 334ASN A 333GLY A 336ALA A 386GLY A 384 | None | 1.28A | 4a6nA-5cerA:undetectable | 4a6nA-5cerA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csu | 4-ALPHA-GLUCANOTRANSFERASE DPE1,CHLOROPLASTIC/AMYLOPLASTIC (Arabidopsisthaliana) |
PF02446(Glyco_hydro_77) | 5 | ARG A 359GLY A 292PRO A 135ALA A 137GLY A 138 | NoneNoneNoneGLC A 605 ( 4.1A)None | 1.09A | 4a6nA-5csuA:1.0 | 4a6nA-5csuA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dgq | PUTATIVEENDOGLUCANASE-RELATED PROTEIN (Photobacteriumprofundum) |
PF00759(Glyco_hydro_9) | 5 | GLN A 346PHE A 405ASN A 404ALA A 372GLY A 373 | None | 1.20A | 4a6nA-5dgqA:undetectable | 4a6nA-5dgqA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7s | GLYCOSIDE HYDROLASEFAMILY 31 (Trueperellapyogenes) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 5 | GLY A 279ALA A 550GLY A 551GLU A 180MET A 213 | None | 1.16A | 4a6nA-5f7sA:undetectable | 4a6nA-5f7sA:18.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5frt | DIMERIC (2FE-2S)PROTEIN (Azotobactervinelandii) |
PF00111(Fer2) | 5 | PHE A 115GLY A 117GLY A 29GLU A 33ASN A 34 | None | 1.33A | 4a6nA-5frtA:undetectable | 4a6nA-5frtA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ft6 | CYSTEINE DESULFURASECSDA (Escherichiacoli) |
PF00266(Aminotran_5) | 5 | GLN A 168PHE A 218GLY A 197ALA A 73GLU A 70 | None | 1.18A | 4a6nA-5ft6A:undetectable | 4a6nA-5ft6A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gpr | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 5 | PHE A 309ASN A 316GLY A 312GLY A 266MET A 381 | PHE A 309 ( 1.3A)ASN A 316 ( 0.6A)GLY A 312 ( 0.0A)GLY A 266 ( 0.0A)MET A 381 ( 0.0A) | 1.13A | 4a6nA-5gprA:undetectable | 4a6nA-5gprA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gqq | HEME-BINDING PROTEIN2 (Homo sapiens) |
PF04832(SOUL) | 5 | ASN A 70GLY A 65ALA A 177GLY A 178GLU A 191 | None | 1.17A | 4a6nA-5gqqA:undetectable | 4a6nA-5gqqA:17.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7j | ELONGATION FACTOR 2 (Pyrococcushorikoshii) |
no annotation | 5 | GLY A 438PRO A 628ALA A 698GLY A 699GLU A 670 | None | 1.20A | 4a6nA-5h7jA:undetectable | 4a6nA-5h7jA:11.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ito | NOPALINE-BINDINGPERIPLASMIC PROTEIN (Agrobacteriumfabrum) |
PF00497(SBP_bac_3) | 5 | PHE A 162GLY A 163GLY A 227GLU A 149MET A 178 | None | 1.24A | 4a6nA-5itoA:undetectable | 4a6nA-5itoA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringae groupgenomosp. 3) |
no annotation | 5 | GLN A 349ASN A 297GLY A 404ALA A 268GLY A 244 | NoneNoneNoneNoneNAD A 700 (-2.9A) | 1.26A | 4a6nA-5iuwA:undetectable | 4a6nA-5iuwA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5je8 | 3-HYDROXYISOBUTYRATEDEHYDROGENASE (Bacillus cereus) |
PF03446(NAD_binding_2)PF14833(NAD_binding_11) | 5 | PHE A 135ASN A 157GLY A 152ALA A 118GLY A 138 | None | 1.35A | 4a6nA-5je8A:4.2 | 4a6nA-5je8A:24.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k1z | AMINODEOXYFUTALOSINENUCLEOSIDASE (Helicobacterpylori) |
PF01048(PNP_UDP_1) | 5 | PHE A 208ASN A 199GLY A 205ALA A 216MET A 10 | 4CT A 301 (-3.5A)NoneNoneNone4CT A 301 ( 2.9A) | 1.34A | 4a6nA-5k1zA:undetectable | 4a6nA-5k1zA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kf7 | BIFUNCTIONAL PROTEINPUTA (Sinorhizobiummeliloti) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 5 | GLN A1191ASN A1201PRO A 804ALA A1170GLY A 802 | None | 1.31A | 4a6nA-5kf7A:undetectable | 4a6nA-5kf7A:14.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lw7 | ABC TRANSPORTERATP-BINDING PROTEIN (Pyrococcusabyssi) |
PF00005(ABC_tran)PF00037(Fer4)PF04068(RLI) | 5 | GLN B 410ARG B 210GLY B 217GLY B 536GLU B 534 | None | 0.92A | 4a6nA-5lw7B:undetectable | 4a6nA-5lw7B:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqs | BETA-L-ARABINOBIOSIDASE (Bacteroidesthetaiotaomicron) |
PF13088(BNR_2) | 5 | ASN A 169GLY A 155ALA A 94ASN A 76MET A 399 | None | 1.30A | 4a6nA-5mqsA:undetectable | 4a6nA-5mqsA:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mvd | DIHYDROOROTATEDEHYDROGENASE(QUINONE),MITOCHONDRIAL (Homo sapiens) |
PF01180(DHO_dh) | 5 | GLY A 128ALA A 96GLY A 97GLU A 117ASN A 181 | NoneFMN A 401 (-3.4A)FMN A 401 (-3.3A)NoneFMN A 401 (-3.1A) | 1.25A | 4a6nA-5mvdA:undetectable | 4a6nA-5mvdA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mzs | FERRIC ENTEROBACTINRECEPTOR (Pseudomonasaeruginosa) |
no annotation | 5 | ARG A 104GLY A 694ALA A 480GLY A 481GLU A 386 | None | 1.31A | 4a6nA-5mzsA:undetectable | 4a6nA-5mzsA:11.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ng6 | CRISPR-ASSOCIATEDENDONUCLEASE CPF1 (Francisellatularensis) |
no annotation | 5 | ASN A1093GLY A1090ALA A1079GLY A1080GLU A1006 | None | 1.03A | 4a6nA-5ng6A:undetectable | 4a6nA-5ng6A:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nvm | EUKARYOTICTRANSLATIONINITIATION FACTOR 4ETYPE 2 (Homo sapiens) |
PF01652(IF4E) | 5 | GLN A 84ASN A 59GLY A 86ALA A 169GLY A 168 | None | 1.03A | 4a6nA-5nvmA:2.2 | 4a6nA-5nvmA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u7s | FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE (Acinetobacterbaumannii) |
PF01116(F_bP_aldolase) | 5 | ARG A 205PHE A 203GLY A 257ALA A 213GLY A 209 | None | 1.26A | 4a6nA-5u7sA:undetectable | 4a6nA-5u7sA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wpw | 11S GLOBULIN ISOFORM1 (Cocos nucifera) |
no annotation | 5 | GLN A 109GLY A 110ALA A 63GLY A 64GLU A 62 | None | 1.15A | 4a6nA-5wpwA:undetectable | 4a6nA-5wpwA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wxu | 11S GLOBULIN (Wrightiatinctoria) |
no annotation | 5 | GLN A 108GLY A 109ALA A 62GLY A 63GLU A 61 | None | 1.16A | 4a6nA-5wxuA:undetectable | 4a6nA-5wxuA:10.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgv | PYRE3 (Streptomycesrugosporus) |
no annotation | 5 | GLN A 56ARG A 322ASN A 297GLY A 440GLY A 289 | None | 1.33A | 4a6nA-5xgvA:26.8 | 4a6nA-5xgvA:14.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xm3 | GLUCOSEDEHYDROGENASE (Methylophagaaminisulfidivorans) |
no annotation | 5 | ASN A 264GLY A 233ALA A 207GLY A 210ASN A 292 | NoneNonePQQ A 701 (-3.0A)None MG A 702 ( 3.0A) | 1.30A | 4a6nA-5xm3A:undetectable | 4a6nA-5xm3A:13.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xns | CHROMOSOME PARTITIONPROTEIN SMC (Pyrococcusfuriosus) |
PF02463(SMC_N) | 5 | GLN A1123PHE A 86ASN A 87ALA A 83GLU A 81 | None | 1.11A | 4a6nA-5xnsA:undetectable | 4a6nA-5xnsA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3r | DNA-DEPENDENTPROTEIN KINASECATALYTIC SUBUNIT (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08163(NUC194) | 5 | GLN C3564ARG C3696GLY C3565ALA C3574MET C3796 | None | 1.23A | 4a6nA-5y3rC:undetectable | 4a6nA-5y3rC:7.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ys9 | ACYL-COENZYME AOXIDASE 3 (Yarrowialipolytica) |
no annotation | 5 | ASN A 261GLY A 248ALA A 196GLU A 175ASN A 193 | FAD A 801 (-3.7A)NoneNoneNoneNone | 1.18A | 4a6nA-5ys9A:undetectable | 4a6nA-5ys9A:13.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zl9 | CHITINASE AB (Serratiamarcescens) |
no annotation | 5 | PHE A 316ASN A 323GLY A 319GLY A 273MET A 390 | NoneNoneNoneNoneGOL A 706 (-3.3A) | 1.12A | 4a6nA-5zl9A:undetectable | 4a6nA-5zl9A:12.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MEMBRANE-BOUNDHYDROGENASE SUBUNITALPHAMEMBRANE-BOUNDHYDROGENASE SUBUNITBETA (Pyrococcusfuriosus) |
no annotation | 5 | ARG L 54GLY L 47PRO K 146GLY K 153GLU K 151 | None | 1.25A | 4a6nA-6cfwL:undetectable | 4a6nA-6cfwL:10.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f85 | CYTOCHROME P450CYP260A1 (Sorangiumcellulosum) |
no annotation | 5 | PHE A 38ASN A 7GLY A 39ALA A 383GLY A 377 | None | 1.31A | 4a6nA-6f85A:undetectable | 4a6nA-6f85A:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fay | ODZ3 PROTEIN (Mus musculus) |
no annotation | 5 | ARG A1797PHE A1779ASN A1777ALA A1740ASN A1744 | None | 1.26A | 4a6nA-6fayA:undetectable | 4a6nA-6fayA:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fd5 | - (-) |
no annotation | 5 | PHE A 71GLY A 68ALA A 41GLY A 44GLU A 5 | None | 1.33A | 4a6nA-6fd5A:undetectable | 4a6nA-6fd5A:undetectable |