SIMILAR PATTERNS OF AMINO ACIDS FOR 4A3P_A_ACTA1223

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cz4 VCP-LIKE ATPASE

(Thermoplasma
acidophilum) 		PF02359
(CDC48_N)
PF02933
(CDC48_2) 		4 ASP A 133
THR A  50
LEU A 130
GLU A 131
 None
 1.46A 4a3pA-1cz4A:
undetectable		 4a3pA-1cz4A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ggq OUTER SURFACE
PROTEIN C

(Borreliella
burgdorferi) 		PF01441
(Lipoprotein_6) 		4 ASP A 144
THR A 151
GLU A 157
LYS A 168
 None
 1.09A 4a3pA-1ggqA:
undetectable		 4a3pA-1ggqA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum) 		PF13202
(EF-hand_5) 		4 ASP A 230
THR A 236
LEU A 237
GLU A 241
 None
 1.48A 4a3pA-1ij5A:
undetectable		 4a3pA-1ij5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum) 		PF13202
(EF-hand_5) 		4 THR A  63
LEU A  60
GLU A  75
LYS A  72
 None
 1.43A 4a3pA-1ij5A:
undetectable		 4a3pA-1ij5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1je6 MHC CLASS I
CHAIN-RELATED
PROTEIN

(Homo sapiens) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 ASP A  72
THR A  76
LEU A  73
GLU A  92
 None
 1.32A 4a3pA-1je6A:
0.0		 4a3pA-1je6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcw CERULOPLASMIN

(Homo sapiens) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ASP A 118
THR A1034
GLU A 112
LYS A 109
 None
 1.43A 4a3pA-1kcwA:
0.0		 4a3pA-1kcwA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qx2 VITAMIN D-DEPENDENT
CALCIUM-BINDING
PROTEIN, INTESTINAL

(Bos taurus) 		PF00036
(EF-hand_1) 		4 ASP A  47
THR A  45
LEU A  46
LYS A  25
 None
 1.50A 4a3pA-1qx2A:
undetectable		 4a3pA-1qx2A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t8h YLMD PROTEIN
SEQUENCE HOMOLOGUE

(Geobacillus
stearothermophilus) 		PF02578
(Cu-oxidase_4) 		4 ASP A 112
THR A 111
LEU A 137
GLU A 164
 None
 1.43A 4a3pA-1t8hA:
undetectable		 4a3pA-1t8hA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uas ALPHA-GALACTOSIDASE

(Oryza sativa) 		PF16499
(Melibiase_2)
PF17450
(Melibiase_2_C) 		4 ASP A 198
THR A 194
GLU A 288
LYS A 280
 None
GOL  A1603 (-3.2A)
None
None
 1.20A 4a3pA-1uasA:
0.0		 4a3pA-1uasA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vp8 HYPOTHETICAL PROTEIN
AF0103

(Archaeoglobus
fulgidus) 		PF02887
(PK_C) 		4 THR A 113
LEU A  96
GLU A 133
LYS A 129
 None
None
FMN  A 500 (-4.1A)
FMN  A 500 ( 2.8A)
 1.46A 4a3pA-1vp8A:
undetectable		 4a3pA-1vp8A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrq SARCOSINE OXIDASE
ALPHA SUBUNIT

(Corynebacterium
sp. U-96) 		PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF12831
(FAD_oxidored)
PF13510
(Fer2_4) 		4 ASP A  99
THR A  98
LEU A  22
GLU A  20
 None
 1.48A 4a3pA-1vrqA:
2.5		 4a3pA-1vrqA:
12.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1w6v UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15

(Homo sapiens) 		PF06337
(DUSP) 		4 ASP A  15
THR A  18
LEU A  19
LYS A  99
 None
 0.71A 4a3pA-1w6vA:
18.6		 4a3pA-1w6vA:
99.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wzo HPCE

(Thermus
thermophilus) 		PF01557
(FAA_hydrolase) 		4 ASP A 168
THR A 185
LEU A 169
GLU A 233
 None
 1.46A 4a3pA-1wzoA:
undetectable		 4a3pA-1wzoA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9b HYPOTHETICAL
MEMBRANE PROTEIN
TA0354_69_121

(Thermoplasma
acidophilum) 		PF11433
(DUF3198) 		4 ASP A  44
LEU A  43
GLU A  29
LYS A  47
 None
 1.25A 4a3pA-1x9bA:
undetectable		 4a3pA-1x9bA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yjg SURFACE PROTEIN VSPA

(Borrelia
turicatae) 		PF01441
(Lipoprotein_6) 		4 ASP A  60
THR A  63
LEU A  64
LYS A 108
 None
 0.97A 4a3pA-1yjgA:
undetectable		 4a3pA-1yjgA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bb6 TRANSCOBALAMIN II

(Bos taurus) 		PF01122
(Cobalamin_bind) 		4 ASP A 389
THR A 390
LEU A 385
GLU A 408
 None
 1.46A 4a3pA-2bb6A:
5.4		 4a3pA-2bb6A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bc0 NADH OXIDASE

(Streptococcus
pyogenes) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ASP A 201
THR A 205
LEU A 204
LYS A 388
 None
 1.17A 4a3pA-2bc0A:
undetectable		 4a3pA-2bc0A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bre ATP-DEPENDENT
MOLECULAR CHAPERONE
HSP82

(Saccharomyces
cerevisiae) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 ASP A 161
THR A 159
LEU A 160
GLU A 162
 None
 1.42A 4a3pA-2breA:
undetectable		 4a3pA-2breA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d8n RECOVERIN

(Homo sapiens) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		4 ASP A  74
THR A  80
LEU A  81
GLU A  85
 None
 1.31A 4a3pA-2d8nA:
undetectable		 4a3pA-2d8nA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dmg KIAA1228 PROTEIN

(Homo sapiens) 		PF00168
(C2) 		4 ASP A  94
THR A  92
LEU A 115
LYS A 113
 None
 1.27A 4a3pA-2dmgA:
undetectable		 4a3pA-2dmgA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ga0 SURFACE PROTEIN VSPA

(Borrelia
turicatae) 		PF01441
(Lipoprotein_6) 		4 ASP A  60
THR A  63
LEU A  64
LYS A 108
 None
 1.00A 4a3pA-2ga0A:
undetectable		 4a3pA-2ga0A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ggq 401AA LONG
HYPOTHETICAL
GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E

(Sulfurisphaera
tokodaii) 		PF00132
(Hexapep)
PF00483
(NTP_transferase) 		4 THR A 113
LEU A 114
GLU A 116
LYS A 198
 None
 1.46A 4a3pA-2ggqA:
undetectable		 4a3pA-2ggqA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2het RECOVERIN

(Bos taurus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		4 ASP A  74
THR A  80
LEU A  81
GLU A  85
 None
 1.26A 4a3pA-2hetA:
undetectable		 4a3pA-2hetA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j66 BTRK

(Bacillus
circulans) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 ASP A  23
LEU A  21
GLU A   7
LYS A 395
 None
 1.42A 4a3pA-2j66A:
undetectable		 4a3pA-2j66A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m41 ATAXIN-1

(Homo sapiens) 		PF08517
(AXH) 		4 ASP B 598
LEU B 583
GLU B 587
LYS B 589
 None
 1.48A 4a3pA-2m41B:
undetectable		 4a3pA-2m41B:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p18 GLYOXALASE II

(Leishmania
infantum) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		4 ASP A 201
THR A 204
LEU A 257
LYS A 261
 None
 1.21A 4a3pA-2p18A:
undetectable		 4a3pA-2p18A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pff FATTY ACID SYNTHASE
SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF16073
(SAT) 		4 ASP B  52
THR B 119
LEU B 108
GLU B  53
 None
 1.43A 4a3pA-2pffB:
undetectable		 4a3pA-2pffB:
5.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qyt 2-DEHYDROPANTOATE
2-REDUCTASE

(Porphyromonas
gingivalis) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 ASP A  73
THR A  72
LEU A  46
GLU A  47
 None
 1.36A 4a3pA-2qytA:
undetectable		 4a3pA-2qytA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wim NEURAL CELL ADHESION
MOLECULE 2

(Homo sapiens) 		PF07679
(I-set) 		4 ASP A 197
THR A 116
LEU A 115
GLU A 195
 None
 1.50A 4a3pA-2wimA:
undetectable		 4a3pA-2wimA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wy3 MHC CLASS I
POLYPEPTIDE-RELATED
SEQUENCE B

(Homo sapiens) 		PF00129
(MHC_I) 		4 ASP A  72
THR A  76
LEU A  73
GLU A  92
 None
 1.30A 4a3pA-2wy3A:
undetectable		 4a3pA-2wy3A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x4g NUCLEOSIDE-DIPHOSPHA
TE-SUGAR EPIMERASE

(Pseudomonas
aeruginosa) 		PF01370
(Epimerase) 		4 ASP A 306
THR A 241
LEU A 239
GLU A 140
 None
 1.28A 4a3pA-2x4gA:
undetectable		 4a3pA-2x4gA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xl4 LMO0438 PROTEIN

(Listeria
monocytogenes) 		no annotation 4 ASP A 202
THR A 184
LEU A 200
GLU A  75
 None
 1.43A 4a3pA-2xl4A:
undetectable		 4a3pA-2xl4A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xy2 NEURAL CELL ADHESION
MOLECULE 2

(Homo sapiens) 		PF07679
(I-set) 		4 ASP A 197
THR A 116
LEU A 115
GLU A 195
 None
 1.44A 4a3pA-2xy2A:
2.3		 4a3pA-2xy2A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cb5 FACT COMPLEX SUBUNIT
SPT16

(Schizosaccharomyces
pombe) 		PF00557
(Peptidase_M24)
PF14826
(FACT-Spt16_Nlob) 		4 ASP A  27
THR A  30
LEU A  31
LYS A 171
 None
 1.44A 4a3pA-3cb5A:
undetectable		 4a3pA-3cb5A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ez4 3-METHYL-2-OXOBUTANO
ATE
HYDROXYMETHYLTRANSFE
RASE

(Burkholderia
pseudomallei) 		PF02548
(Pantoate_transf) 		4 ASP A  61
THR A  59
LEU A  60
LYS A 100
 None
 1.49A 4a3pA-3ez4A:
undetectable		 4a3pA-3ez4A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gq9 PRENECK APPENDAGE
PROTEIN

(Bacillus virus
phi29) 		PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3) 		4 ASP A 312
THR A 283
GLU A 333
LYS A 335
 NA  A 692 (-3.3A)
None
None
NA  A 692 ( 4.0A)
 1.14A 4a3pA-3gq9A:
undetectable		 4a3pA-3gq9A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hea ARYLESTERASE

(Pseudomonas
fluorescens) 		PF00561
(Abhydrolase_1) 		4 ASP A 264
LEU A 215
GLU A 242
LYS A 244
 None
 1.06A 4a3pA-3heaA:
undetectable		 4a3pA-3heaA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksu 3-OXOACYL-ACYL
CARRIER PROTEIN
REDUCTASE

(Oenococcus oeni) 		PF13561
(adh_short_C2) 		4 THR A  48
LEU A  52
GLU A  55
LYS A  27
 None
 1.35A 4a3pA-3ksuA:
undetectable		 4a3pA-3ksuA:
22.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3lmn UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15

(Homo sapiens) 		PF06337
(DUSP) 		5 ASP A  15
THR A  18
LEU A  19
GLU A  95
LYS A  99
 None
 0.42A 4a3pA-3lmnA:
20.0		 4a3pA-3lmnA:
94.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3msy MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(marine
actinobacterium
PHSC20C1) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ASP A 278
THR A 282
LEU A 279
GLU A 270
 None
 1.08A 4a3pA-3msyA:
undetectable		 4a3pA-3msyA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6r PROPIONYL-COA
CARBOXYLASE, BETA
SUBUNIT

(Roseobacter
denitrificans) 		PF01039
(Carboxyl_trans) 		4 THR B 304
LEU B 305
GLU B 318
LYS B 322
 None
 1.03A 4a3pA-3n6rB:
undetectable		 4a3pA-3n6rB:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3od1 ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT

(Bacillus
halodurans) 		PF13393
(tRNA-synt_His) 		4 ASP A 133
THR A 311
LEU A 130
GLU A 141
 None
 1.39A 4a3pA-3od1A:
undetectable		 4a3pA-3od1A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppc 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE

(Candida
albicans) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		4 THR A 144
LEU A 142
GLU A 202
LYS A 206
 None
 1.31A 4a3pA-3ppcA:
undetectable		 4a3pA-3ppcA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qhy BETA-LACTAMASE

(Bacillus
anthracis) 		PF13354
(Beta-lactamase2) 		4 ASP A 163
THR A 180
GLU A 149
LYS A 146
 None
 1.12A 4a3pA-3qhyA:
undetectable		 4a3pA-3qhyA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rhd LACTALDEHYDE
DEHYDROGENASE

(Methanocaldococcus
jannaschii) 		PF00171
(Aldedh) 		4 ASP A 403
THR A 401
LEU A 251
GLU A 381
 None
 1.40A 4a3pA-3rhdA:
0.4		 4a3pA-3rhdA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rn2 INTERFERON-INDUCIBLE
PROTEIN AIM2

(Homo sapiens) 		PF02760
(HIN) 		4 ASP A 283
THR A 274
LEU A 281
GLU A 292
 None
 1.13A 4a3pA-3rn2A:
undetectable		 4a3pA-3rn2A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rv1 K. POLYSPORUS DCR1

(Vanderwaltozyma
polyspora) 		PF00636
(Ribonuclease_3) 		4 ASP A 241
THR A 237
LEU A 240
GLU A 244
 None
 1.47A 4a3pA-3rv1A:
undetectable		 4a3pA-3rv1A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s84 APOLIPOPROTEIN A-IV

(Homo sapiens) 		PF01442
(Apolipoprotein) 		4 ASP A 206
THR A 202
GLU A 250
LYS A 209
 None
 1.03A 4a3pA-3s84A:
undetectable		 4a3pA-3s84A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suc PRENECK APPENDAGE
PROTEIN

(Bacillus virus
phi29) 		PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3) 		4 ASP A 312
THR A 283
GLU A 333
LYS A 335
 MG  A 857 (-3.4A)
MG  A 857 ( 4.9A)
None
CA  A   1 ( 4.6A)
 1.16A 4a3pA-3sucA:
undetectable		 4a3pA-3sucA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tch PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 ASP A 349
THR A 348
GLU A 448
LYS A 183
 None
 1.34A 4a3pA-3tchA:
undetectable		 4a3pA-3tchA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3th6 TRIOSEPHOSPHATE
ISOMERASE

(Rhipicephalus
microplus) 		PF00121
(TIM) 		4 ASP A 179
THR A 177
GLU A 219
LYS A 223
 None
 1.42A 4a3pA-3th6A:
undetectable		 4a3pA-3th6A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vmn DEXTRANASE

(Streptococcus
mutans) 		PF13199
(Glyco_hydro_66) 		4 ASP A 512
THR A 518
LEU A 566
GLU A 495
 None
 1.12A 4a3pA-3vmnA:
undetectable		 4a3pA-3vmnA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		4 THR A 430
LEU A 431
GLU A 439
LYS A 440
 None
 0.99A 4a3pA-3vuvA:
undetectable		 4a3pA-3vuvA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x17 ENDOGLUCANASE

(uncultured
bacterium) 		no annotation 4 ASP B 404
THR B 407
LEU B 408
GLU B 217
 None
 1.27A 4a3pA-3x17B:
undetectable		 4a3pA-3x17B:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0k CULLIN-4A

(Homo sapiens) 		PF00888
(Cullin)
PF10557
(Cullin_Nedd8) 		4 ASP A 434
THR A 432
LEU A 433
LYS A 478
 None
 1.24A 4a3pA-4a0kA:
undetectable		 4a3pA-4a0kA:
14.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4a3p UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15

(Homo sapiens) 		PF06337
(DUSP)
PF14836
(Ubiquitin_3) 		5 ASP A  15
THR A  18
LEU A  19
GLU A  95
LYS A  99
 ACT  A1223 (-3.2A)
ACT  A1223 ( 3.9A)
ACT  A1223 (-4.5A)
ACT  A1223 (-2.8A)
ACT  A1223 (-2.8A)
 0.00A 4a3pA-4a3pA:
32.4		 4a3pA-4a3pA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4arc LEUCINE--TRNA LIGASE

(Escherichia
coli) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2) 		4 ASP A 704
THR A 708
GLU A 731
LYS A 735
 None
None
A  B  22 ( 3.1A)
None
 1.42A 4a3pA-4arcA:
4.2		 4a3pA-4arcA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b6x AVIRULENCE PROTEIN

(Pseudomonas
syringae) 		no annotation 4 ASP A 201
LEU A 205
GLU A 161
LYS A 165
 None
 0.86A 4a3pA-4b6xA:
undetectable		 4a3pA-4b6xA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4btf MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN

(Mus musculus) 		PF07714
(Pkinase_Tyr) 		4 ASP A 289
THR A 291
LEU A 290
GLU A 287
 None
 0.86A 4a3pA-4btfA:
undetectable		 4a3pA-4btfA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e1j GLYCEROL KINASE

(Sinorhizobium
meliloti) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ASP A 222
THR A 226
LEU A 225
LYS A 149
 None
 1.29A 4a3pA-4e1jA:
undetectable		 4a3pA-4e1jA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f21 CARBOXYLESTERASE/PHO
SPHOLIPASE FAMILY
PROTEIN

(Francisella
tularensis) 		PF02230
(Abhydrolase_2) 		4 ASP A 211
LEU A 163
GLU A 193
LYS A 195
 None
 1.07A 4a3pA-4f21A:
undetectable		 4a3pA-4f21A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gmj CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1

(Homo sapiens) 		PF16415
(CNOT1_CAF1_bind) 		4 THR A1178
LEU A1316
GLU A1223
LYS A1227
 None
 1.19A 4a3pA-4gmjA:
undetectable		 4a3pA-4gmjA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3g BETA-GLUCOSIDASE

(Streptomyces
venezuelae) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 ASP A  63
THR A  61
LEU A  62
LYS A 316
 None
 1.33A 4a3pA-4i3gA:
0.8		 4a3pA-4i3gA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ita SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE

(Synechococcus
sp. PCC 7002) 		PF00171
(Aldedh) 		4 ASP A 244
LEU A 243
GLU A 277
LYS A 281
 None
 0.93A 4a3pA-4itaA:
0.3		 4a3pA-4itaA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jrf PUTATIVE CELL
ADHESION PROTEIN

(Bacteroides
ovatus) 		PF15495
(Fimbrillin_C) 		4 ASP A 152
THR A 150
LEU A 151
LYS A 159
 None
 1.47A 4a3pA-4jrfA:
undetectable		 4a3pA-4jrfA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kf8 NUP188

(Thermothelomyces
thermophila) 		no annotation 4 THR A1549
LEU A1605
GLU A1601
LYS A1661
 None
 1.43A 4a3pA-4kf8A:
undetectable		 4a3pA-4kf8A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m73 METHYLTRANSFERASE
MPPJ

(Streptomyces
hygroscopicus) 		PF13649
(Methyltransf_25) 		4 ASP A 309
THR A 304
LEU A 305
LYS A 322
 HF2  A 404 ( 3.3A)
None
None
HF2  A 404 ( 3.0A)
 1.47A 4a3pA-4m73A:
undetectable		 4a3pA-4m73A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4phq HEMOLYSIN E,
CHROMOSOMAL

(Escherichia
coli) 		PF06109
(HlyE) 		4 ASP A  64
THR A  67
LEU A  68
LYS A 147
 None
 0.88A 4a3pA-4phqA:
undetectable		 4a3pA-4phqA:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q04 URE3-BP SEQUENCE
SPECIFIC DNA BINDING
PROTEIN

(Entamoeba
histolytica) 		PF13499
(EF-hand_7) 		4 ASP A 127
THR A 133
LEU A 134
GLU A 138
 NA  A 301 (-3.2A)
None
None
NA  A 301 ( 4.9A)
 1.33A 4a3pA-4q04A:
undetectable		 4a3pA-4q04A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qi4 CELLOBIOSE
DEHYDROGENASE

(Crassicarpon
hotsonii) 		PF00732
(GMC_oxred_N)
PF00734
(CBM_1)
PF05199
(GMC_oxred_C) 		4 ASP A 281
THR A 283
LEU A 282
GLU A 414
 None
 1.20A 4a3pA-4qi4A:
undetectable		 4a3pA-4qi4A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore) 		4 ASP A 805
THR A 808
LEU A 809
GLU A 767
 None
 1.00A 4a3pA-4r04A:
undetectable		 4a3pA-4r04A:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Vibrio cholerae) 		PF00275
(EPSP_synthase) 		4 ASP A  86
THR A  90
LEU A  87
GLU A  56
 None
 1.28A 4a3pA-4r7uA:
undetectable		 4a3pA-4r7uA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9n LMO0547 PROTEIN

(Listeria
monocytogenes) 		PF04198
(Sugar-bind) 		4 ASP A 304
THR A  61
LEU A  64
GLU A 308
 None
 1.26A 4a3pA-4r9nA:
undetectable		 4a3pA-4r9nA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u4p STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
2

(Homo sapiens) 		PF06470
(SMC_hinge) 		4 ASP A 488
LEU A 492
GLU A 687
LYS A 691
 None
 0.63A 4a3pA-4u4pA:
undetectable		 4a3pA-4u4pA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uv2 CURLI PRODUCTION
TRANSPORT COMPONENT
CSGG

(Escherichia
coli) 		PF03783
(CsgG) 		4 ASP A  74
THR A  25
LEU A  24
GLU A 221
 None
 0.87A 4a3pA-4uv2A:
undetectable		 4a3pA-4uv2A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w64 TYPE VI SECRETION
SYSTEM EFFECTOR,
HCP1 FAMILY

(Acinetobacter
baumannii) 		PF05638
(T6SS_HCP) 		4 ASP A  67
LEU A  66
GLU A 126
LYS A  64
 None
 0.94A 4a3pA-4w64A:
undetectable		 4a3pA-4w64A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xjx HSDR

(Escherichia
coli) 		PF04313
(HSDR_N)
PF04851
(ResIII)
PF12008
(EcoR124_C) 		4 ASP A 881
THR A 696
LEU A 882
GLU A 879
 None
 1.41A 4a3pA-4xjxA:
undetectable		 4a3pA-4xjxA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y90 TRIOSEPHOSPHATE
ISOMERASE

(Deinococcus
radiodurans) 		PF00121
(TIM) 		4 ASP A 178
THR A 176
GLU A 217
LYS A 221
 None
 1.22A 4a3pA-4y90A:
undetectable		 4a3pA-4y90A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yfm BETA-LACTAMASE

(Mycobacteroides
abscessus) 		PF13354
(Beta-lactamase2) 		4 ASP A 164
THR A 179
GLU A 150
LYS A 147
 None
 1.12A 4a3pA-4yfmA:
undetectable		 4a3pA-4yfmA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywl CELL DIVISION
CONTROL PROTEIN 21

(Pyrococcus
furiosus) 		PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 ASP A 189
THR A 193
LEU A 194
GLU A 198
 None
 1.37A 4a3pA-4ywlA:
undetectable		 4a3pA-4ywlA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zze SUGAR BINDING
PROTEIN OF ABC
TRANSPORTER SYSTEM

(Bifidobacterium
animalis) 		PF01547
(SBP_bac_1) 		4 THR A 228
LEU A 229
GLU A 251
LYS A 255
 None
 1.02A 4a3pA-4zzeA:
undetectable		 4a3pA-4zzeA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a5t EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT A

(Oryctolagus
cuniculus) 		PF01399
(PCI) 		4 THR A 320
LEU A 324
GLU A 423
LYS A 278
 None
 1.31A 4a3pA-5a5tA:
undetectable		 4a3pA-5a5tA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8q PUTATIVE RETAINING
B-GLYCOSIDASE

(Saccharophagus
degradans) 		PF00150
(Cellulase) 		4 ASP A 132
LEU A 133
GLU A  91
LYS A  87
 None
 1.43A 4a3pA-5a8qA:
undetectable		 4a3pA-5a8qA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ch8 MONO- AND
DIACYLGLYCEROL
LIPASE

(Penicillium
cyclopium) 		PF01764
(Lipase_3)
PF03893
(Lipase3_N) 		4 ASP A   8
THR A   4
LEU A   7
GLU A  11
 ZN  A 302 (-4.6A)
None
None
None
 1.22A 4a3pA-5ch8A:
undetectable		 4a3pA-5ch8A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d7l MAV36 TCR ALPHA
CHAIN

(Homo sapiens) 		PF07686
(V-set)
PF09291
(DUF1968) 		4 ASP D  83
THR D  81
GLU D  39
LYS D  37
 None
 1.28A 4a3pA-5d7lD:
undetectable		 4a3pA-5d7lD:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gt2 PROBABLE
DEFERROCHELATASE/PER
OXIDASE YFEX

(Escherichia
coli) 		PF04261
(Dyp_perox) 		4 ASP A 221
THR A 218
LEU A 217
GLU A 205
 HEM  A 401 ( 3.9A)
None
HEM  A 401 ( 4.6A)
None
 1.23A 4a3pA-5gt2A:
undetectable		 4a3pA-5gt2A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ko1 MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 ASP A 300
THR A 302
LEU A 301
GLU A 298
 None
 1.05A 4a3pA-5ko1A:
undetectable		 4a3pA-5ko1A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5loq PUTATIVE
HEME-DEPENDENT
PEROXIDASE LMO2113

(Listeria
monocytogenes) 		PF06778
(Chlor_dismutase) 		4 ASP A  16
THR A  74
LEU A  14
GLU A  86
 None
 1.38A 4a3pA-5loqA:
undetectable		 4a3pA-5loqA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4l CERULOPLASMIN

(Rattus
norvegicus) 		no annotation 4 ASP A 118
THR A1028
GLU A 112
LYS A 109
 CA  A1106 (-4.3A)
None
CA  A1106 (-4.7A)
CA  A1106 (-4.4A)
 1.36A 4a3pA-5n4lA:
undetectable		 4a3pA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1

(Pseudomonas
syringae) 		no annotation 4 ASP A 238
THR A 216
LEU A 215
LYS A  58
 None
 1.37A 4a3pA-5t09A:
undetectable		 4a3pA-5t09A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vbc PROBABLE
HISTONE-LYSINE
N-METHYLTRANSFERASE
ATXR5

(Ricinus
communis) 		PF00856
(SET) 		4 ASP A 194
THR A 196
LEU A 195
GLU A 268
 None
 1.47A 4a3pA-5vbcA:
undetectable		 4a3pA-5vbcA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byi BETA-MANNOSIDASE

(Xanthomonas
citri) 		no annotation 4 ASP A 783
THR A 786
LEU A 788
GLU A 701
 None
 0.87A 4a3pA-6byiA:
undetectable		 4a3pA-6byiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cb8 GASDERMIN-A3

(Mus musculus) 		no annotation 4 ASP A  20
THR A  22
LEU A  21
GLU A 156
 None
 1.42A 4a3pA-6cb8A:
undetectable		 4a3pA-6cb8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ck9 GP41 ECTODOMAIN OF
ENVELOPE
GLYCOPROTEIN GP160
35O22 SCFV HEAVY
CHAIN PORTION

(Human
immunodeficiency
virus 1;
Homo sapiens) 		no annotation
no annotation 		4 ASP B 624
THR D 100
LEU D  97
GLU B 620
 None
NAG  G 882 (-4.0A)
None
None
 1.12A 4a3pA-6ck9B:
undetectable		 4a3pA-6ck9B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cri -

(-) 		no annotation 4 ASP G 298
THR G 295
LEU G 294
LYS G 334
 None
 1.36A 4a3pA-6criG:
undetectable		 4a3pA-6criG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f4c ALPHA-GALACTOSIDASE

(Nicotiana
benthamiana) 		no annotation 4 ASP B 249
THR B 245
GLU B 339
LYS B 331
 None
 1.26A 4a3pA-6f4cB:
undetectable		 4a3pA-6f4cB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fah CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARC

(Acetobacterium
woodii) 		no annotation 4 ASP C 286
THR C 289
GLU C 328
LYS C 332
 SO4  C 404 (-3.0A)
None
None
None
 1.21A 4a3pA-6fahC:
undetectable		 4a3pA-6fahC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g43 PUTATIVE MAJOR
CAPSID PROTEIN

(Cafeteriavirus-dependent
mavirus) 		no annotation 4 ASP A 256
THR A 258
GLU A  78
LYS A  80
 None
 1.35A 4a3pA-6g43A:
undetectable		 4a3pA-6g43A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g45 PUTATIVE MAJOR
CAPSID PROTEIN

(Cafeteriavirus-dependent
mavirus) 		no annotation 4 ASP A 256
THR A 258
GLU A  78
LYS A  80
 None
 1.36A 4a3pA-6g45A:
undetectable		 4a3pA-6g45A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE

(Homo sapiens) 		no annotation 4 THR A 235
LEU A 234
GLU A 363
LYS A 285
 None
 1.24A 4a3pA-6gqdA:
undetectable		 4a3pA-6gqdA:
undetectable