SIMILAR PATTERNS OF AMINO ACIDS FOR 3ZQT_A_30ZA1920_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ab6 | CHEMOTAXIS PROTEINCHEY (Escherichiacoli) |
PF00072(Response_reg) | 4 | GLY A 52LEU A 6ASN A 32GLU A 34 | None | 0.97A | 3zqtA-1ab6A:undetectable | 3zqtA-1ab6A:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1as4 | ANTICHYMOTRYPSIN (Homo sapiens) |
PF00079(Serpin) | 4 | GLY A 139ASN A 116LEU A 100ASN A 104 | None | 1.02A | 3zqtA-1as4A:0.0 | 3zqtA-1as4A:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b0k | PROTEIN (ACONITASE) (Sus scrofa) |
PF00330(Aconitase)PF00694(Aconitase_C) | 5 | PRO A 243GLY A 244LEU A 315ASN A 314GLU A 312 | None | 1.44A | 3zqtA-1b0kA:0.0 | 3zqtA-1b0kA:17.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b0k | PROTEIN (ACONITASE) (Sus scrofa) |
PF00330(Aconitase)PF00694(Aconitase_C) | 4 | PRO A 325GLY A 324ASN A 323GLU A 344 | None | 0.98A | 3zqtA-1b0kA:0.0 | 3zqtA-1b0kA:17.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bwd | PROTEIN(INOSAMINE-PHOSPHATEAMIDINOTRANSFERASE) (Streptomycesgriseus) |
no annotation | 4 | PRO A 317LEU A 294ASN A 314GLU A 309 | None | 1.03A | 3zqtA-1bwdA:0.0 | 3zqtA-1bwdA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6y | METHYL-COENZYME MREDUCTASE SUBUNITALPHA (Methanosarcinabarkeri) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 4 | PRO A1292GLY A1293ASN A1494LEU A1281 | NoneNoneAGM A1285 ( 3.7A)AGM A1285 ( 3.8A) | 0.81A | 3zqtA-1e6yA:0.0 | 3zqtA-1e6yA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eav | MOLYBDOPTERINBIOSYNTHESIS CNX1PROTEIN (Arabidopsisthaliana) |
PF00994(MoCF_biosynth) | 4 | PRO A 138GLY A 139ASN A 142GLU A 146 | None | 1.01A | 3zqtA-1eavA:0.0 | 3zqtA-1eavA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1exe | TRANSCRIPTION FACTOR1 (Bacillus virusSPO1) |
PF00216(Bac_DNA_binding) | 4 | PRO A 81GLY A 82LEU A 48ASN A 49 | None | 1.00A | 3zqtA-1exeA:undetectable | 3zqtA-1exeA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g01 | ENDOGLUCANASE (Bacillus sp.KSM-635) |
PF00150(Cellulase)PF03424(CBM_17_28) | 4 | PRO A 338GLY A 336ASN A 377ASN A 372 | NoneNoneNone CD A 591 ( 4.8A) | 0.84A | 3zqtA-1g01A:undetectable | 3zqtA-1g01A:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8k | ARSENITE OXIDASE (Alcaligenesfaecalis) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 4 | PRO A 303GLY A 304ASN A 391LEU A 683 | NoneMGD A5002 (-3.6A)NoneNone | 0.87A | 3zqtA-1g8kA:0.0 | 3zqtA-1g8kA:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j3j | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Plasmodiumfalciparum) |
PF00303(Thymidylat_synt) | 4 | GLY C 393ASN C 424LEU C 397ASN C 398 | None | 1.01A | 3zqtA-1j3jC:0.0 | 3zqtA-1j3jC:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jig | DLP-2 (Bacillusanthracis) |
PF00210(Ferritin) | 4 | PRO A 69GLY A 67LEU A 65GLU A 60 | NoneNoneNone FE A 402 (-2.4A) | 0.98A | 3zqtA-1jigA:undetectable | 3zqtA-1jigA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1la2 | MYO-INOSITOL-1-PHOSPHATE SYNTHASE (Saccharomycescerevisiae) |
PF01658(Inos-1-P_synth)PF07994(NAD_binding_5) | 4 | PRO A 303GLY A 304LEU A 264ASN A 263 | None | 0.96A | 3zqtA-1la2A:undetectable | 3zqtA-1la2A:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mro | METHYL-COENZYME MREDUCTASE (Methanothermobactermarburgensis) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 4 | PRO A 278GLY A 279ASN A 474LEU A 267 | NoneNoneAGM A 271 ( 3.7A)AGM A 271 ( 3.8A) | 0.79A | 3zqtA-1mroA:undetectable | 3zqtA-1mroA:15.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mwp | AMYLOID A4 PROTEIN (Homo sapiens) |
PF02177(APP_N) | 4 | PRO A 56GLY A 58LEU A 41ASN A 42 | None | 0.92A | 3zqtA-1mwpA:undetectable | 3zqtA-1mwpA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n31 | L-CYSTEINE/CYSTINELYASE C-DES (Synechocystissp. PCC 6714) |
PF00266(Aminotran_5) | 4 | GLY A 315LEU A 385ASN A 382GLU A 378 | None | 0.98A | 3zqtA-1n31A:undetectable | 3zqtA-1n31A:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nne | DNA MISMATCH REPAIRPROTEIN MUTS (Thermusaquaticus) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 4 | PRO A 69GLY A 44LEU A 5GLU A 8 | None | 0.97A | 3zqtA-1nneA:undetectable | 3zqtA-1nneA:15.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p16 | MRNA CAPPING ENZYMEALPHA SUBUNIT (Candidaalbicans) |
PF01331(mRNA_cap_enzyme)PF03919(mRNA_cap_C) | 4 | PRO A 13GLY A 14ASN A 15ASN A 101 | None | 1.01A | 3zqtA-1p16A:undetectable | 3zqtA-1p16A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r82 | GLYCOPROTEIN-FUCOSYLGALACTOSIDEALPHA-GALACTOSYLTRANSFERASE (Homo sapiens) |
PF03414(Glyco_transf_6) | 4 | GLY A 230LEU A 310ASN A 307GLU A 303 | NoneNoneNoneAOG A 452 (-2.6A) | 1.00A | 3zqtA-1r82A:undetectable | 3zqtA-1r82A:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s4d | UROPORPHYRIN-IIIC-METHYLTRANSFERASE (Pseudomonasdenitrificans(nomenrejiciendum)) |
PF00590(TP_methylase) | 4 | PRO A 24GLY A 25ASN A 51ASN A 212 | SAH A1501 (-4.9A)NoneNoneNone | 0.98A | 3zqtA-1s4dA:undetectable | 3zqtA-1s4dA:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1upf | URACILPHOSPHORIBOSYLTRANSFERASE (Toxoplasmagondii) |
no annotation | 4 | PRO D 231GLY D 232LEU D 196GLU D 22 | None | 1.00A | 3zqtA-1upfD:undetectable | 3zqtA-1upfD:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vbl | PECTATE LYASE 47 (Bacillus sp.TS-47) |
PF00544(Pec_lyase_C) | 4 | PRO A 177GLY A 183ASN A 186GLU A 174 | None | 1.02A | 3zqtA-1vblA:undetectable | 3zqtA-1vblA:21.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ax9 | ANDROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | PRO A 723GLY A 724ASN A 727LEU A 830ASN A 833 | None | 1.00A | 3zqtA-2ax9A:40.4 | 3zqtA-2ax9A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ax9 | ANDROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | PRO A 723GLY A 724LEU A 830ASN A 833GLU A 837 | None | 0.55A | 3zqtA-2ax9A:40.4 | 3zqtA-2ax9A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3t | FATTY OXIDATIONCOMPLEX ALPHASUBUNIT (Pseudomonasfragi) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 4 | PRO A 496GLY A 497ASN A 501GLU A 558 | None | 1.01A | 3zqtA-2d3tA:undetectable | 3zqtA-2d3tA:15.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2diw | PUTATIVE RNA-BINDINGPROTEIN 16 (Homo sapiens) |
PF04818(CTD_bind) | 4 | PRO A 70GLY A 71LEU A 108GLU A 66 | None | 1.02A | 3zqtA-2diwA:undetectable | 3zqtA-2diwA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2glx | 1,5-ANHYDRO-D-FRUCTOSE REDUCTASE (Ensiferadhaerens) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | PRO A 167GLY A 170ASN A 73LEU A 175 | NoneNoneNDP A1500 (-3.4A)None | 1.00A | 3zqtA-2glxA:undetectable | 3zqtA-2glxA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ix8 | ELONGATION FACTOR 3A (Saccharomycescerevisiae) |
PF00005(ABC_tran) | 4 | PRO A1291GLY A1292ASN A1296LEU A1254 | None | 0.89A | 3zqtA-2ix8A:undetectable | 3zqtA-2ix8A:14.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lf2 | UNCHARACTERIZEDPROTEIN (Cytophagahutchinsonii) |
PF08327(AHSA1) | 4 | PRO A 110LEU A 105ASN A 106GLU A 108 | None | 0.74A | 3zqtA-2lf2A:undetectable | 3zqtA-2lf2A:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mbr | URIDINEDIPHOSPHO-N-ACETYLENOLPYRUVYLGLUCOSAMINEREDUCTASE (Escherichiacoli) |
PF01565(FAD_binding_4)PF02873(MurB_C) | 4 | PRO A 221GLY A 225ASN A 294ASN A 9 | FAD A 401 ( 4.9A)NoneNoneNone | 1.02A | 3zqtA-2mbrA:undetectable | 3zqtA-2mbrA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2n3s | TRANSLATIONINITIATION FACTORIF-1 (Burkholderiathailandensis) |
PF01176(eIF-1a) | 4 | GLY A 29ASN A 28LEU A 26GLU A 12 | None | 0.97A | 3zqtA-2n3sA:undetectable | 3zqtA-2n3sA:14.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nvu | MALTOSE BINDINGPROTEIN/NEDD8-ACTIVATING ENZYME E1CATALYTIC SUBUNITCHIMERA (Homo sapiens) |
PF00899(ThiF)PF08825(E2_bind)PF13416(SBP_bac_8) | 4 | PRO B2171LEU B2162ASN B2163GLU B2165 | None | 0.99A | 3zqtA-2nvuB:undetectable | 3zqtA-2nvuB:14.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nya | PERIPLASMIC NITRATEREDUCTASE (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 4 | GLY A 108ASN A 135LEU A 437ASN A 438 | None | 0.96A | 3zqtA-2nyaA:undetectable | 3zqtA-2nyaA:15.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p58 | PUTATIVE TYPE IIISECRETION PROTEINYSCG (Yersinia pestis) |
PF09477(Type_III_YscG) | 4 | GLY C 62ASN C 63LEU C 74GLU C 39 | None | 0.87A | 3zqtA-2p58C:undetectable | 3zqtA-2p58C:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pd3 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Helicobacterpylori) |
PF13561(adh_short_C2) | 4 | GLY A 228LEU A 141ASN A 184GLU A 242 | None | 0.83A | 3zqtA-2pd3A:undetectable | 3zqtA-2pd3A:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ps2 | PUTATIVE MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Aspergillusoryzae) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | PRO A 173GLY A 171LEU A 201GLU A 204 | None | 0.93A | 3zqtA-2ps2A:undetectable | 3zqtA-2ps2A:23.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q3y | ANCESTRAL CORTICIODRECEPTOR (unidentified) |
PF00104(Hormone_recep) | 4 | PRO A 51GLY A 52ASN A 161GLU A 165 | None | 0.88A | 3zqtA-2q3yA:37.4 | 3zqtA-2q3yA:58.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qdj | RETINOBLASTOMA-ASSOCIATED PROTEIN (Homo sapiens) |
PF11934(DUF3452) | 4 | GLY A 100LEU A 120ASN A 123GLU A 125 | None | 0.75A | 3zqtA-2qdjA:undetectable | 3zqtA-2qdjA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v5d | O-GLCNACASE NAGJ (Clostridiumperfringens) |
PF00754(F5_F8_type_C)PF02838(Glyco_hydro_20b)PF07555(NAGidase) | 4 | PRO A 368GLY A 369ASN A 373GLU A 374 | None | 0.65A | 3zqtA-2v5dA:undetectable | 3zqtA-2v5dA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xax | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1SUBUNIT ALPHA (Escherichiacoli) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 4 | PRO A 673GLY A 674ASN A 675GLU A 671 | None | 0.80A | 3zqtA-2xaxA:undetectable | 3zqtA-2xaxA:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y7d | 3-KETO-5-AMINOHEXANOATE CLEAVAGE ENZYME (CandidatusCloacimonasacidaminovorans) |
PF05853(BKACE) | 4 | PRO A 176GLY A 178LEU A 112ASN A 113 | None | 0.97A | 3zqtA-2y7dA:undetectable | 3zqtA-2y7dA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yev | CYTOCHROME C OXIDASEPOLYPEPTIDE I+III (Thermusthermophilus) |
PF00115(COX1)PF00510(COX3) | 4 | GLY A 235LEU A 724ASN A 723GLU A 722 | None | 0.98A | 3zqtA-2yevA:undetectable | 3zqtA-2yevA:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yia | RNA-DIRECTED RNAPOLYMERASE (Infectiouspancreaticnecrosis virus) |
PF04197(Birna_RdRp) | 4 | PRO A 141GLY A 143LEU A 135ASN A 138 | None | 0.83A | 3zqtA-2yiaA:undetectable | 3zqtA-2yiaA:15.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yib | RNA-DIRECTED RNAPOLYMERASE (Infectiouspancreaticnecrosis virus) |
PF04197(Birna_RdRp) | 4 | PRO D 141GLY D 143LEU D 135ASN D 138 | None | 0.83A | 3zqtA-2yibD:undetectable | 3zqtA-2yibD:17.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3be8 | NEUROLIGIN-4,X-LINKED (Homo sapiens) |
PF00135(COesterase) | 4 | GLY A 68LEU A 62ASN A 64GLU A 65 | NA A 626 ( 4.8A)NoneNoneNone | 0.96A | 3zqtA-3be8A:undetectable | 3zqtA-3be8A:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ejh | COLLAGEN TYPE-I A1CHAINFIBRONECTIN (Homo sapiens) |
PF00039(fn1)no annotation | 4 | PRO E 964GLY E 965LEU A 541GLU A 537 | None | 0.88A | 3zqtA-3ejhE:undetectable | 3zqtA-3ejhE:7.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ek2 | ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE(NADH) (Burkholderiapseudomallei) |
PF13561(adh_short_C2) | 4 | GLY A 229LEU A 142ASN A 185GLU A 243 | None | 0.86A | 3zqtA-3ek2A:undetectable | 3zqtA-3ek2A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fxi | TOLL-LIKE RECEPTOR 4 (Homo sapiens) |
PF13516(LRR_6)PF13855(LRR_8) | 4 | PRO A 489LEU A 508ASN A 486GLU A 485 | None | 0.83A | 3zqtA-3fxiA:undetectable | 3zqtA-3fxiA:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3grk | ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE(NADH) (Brucellamelitensis) |
PF13561(adh_short_C2) | 4 | GLY A 232LEU A 145ASN A 188GLU A 246 | None | 0.92A | 3zqtA-3grkA:undetectable | 3zqtA-3grkA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju8 | SUCCINYLGLUTAMICSEMIALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 4 | GLY A 408ASN A 430LEU A 435ASN A 250 | None | 0.98A | 3zqtA-3ju8A:undetectable | 3zqtA-3ju8A:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ktm | AMYLOID BETA A4PROTEIN (Homo sapiens) |
PF02177(APP_N)PF12924(APP_Cu_bd) | 4 | PRO A 56GLY A 58LEU A 41ASN A 42 | None | 0.99A | 3zqtA-3ktmA:undetectable | 3zqtA-3ktmA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lkd | TYPE IRESTRICTION-MODIFICATION SYSTEMMETHYLTRANSFERASESUBUNIT (Streptococcusthermophilus) |
PF02384(N6_Mtase)PF12161(HsdM_N) | 4 | GLY A 233ASN A 267LEU A 237ASN A 238 | None | 1.01A | 3zqtA-3lkdA:undetectable | 3zqtA-3lkdA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lvu | ABC TRANSPORTER,PERIPLASMICSUBSTRATE-BINDINGPROTEIN (Ruegeriapomeroyi) |
PF00496(SBP_bac_5) | 4 | PRO A 501GLY A 502ASN A 503LEU A 538 | None | 0.84A | 3zqtA-3lvuA:undetectable | 3zqtA-3lvuA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mog | PROBABLE3-HYDROXYBUTYRYL-COADEHYDROGENASE (Escherichiacoli) |
PF00725(3HCDH)PF02737(3HCDH_N) | 4 | PRO A 386GLY A 387LEU A 444ASN A 447 | None | 0.93A | 3zqtA-3mogA:undetectable | 3zqtA-3mogA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o5a | PERIPLASMIC NITRATEREDUCTASE (Cupriavidusnecator) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 4 | GLY A 117ASN A 144LEU A 447ASN A 448 | None | 0.90A | 3zqtA-3o5aA:undetectable | 3zqtA-3o5aA:14.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ot5 | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Listeriamonocytogenes) |
PF02350(Epimerase_2) | 4 | PRO A 293GLY A 294LEU A 181GLU A 290 | NonePGE A 381 (-4.8A)PGE A 381 ( 4.6A)None | 0.97A | 3zqtA-3ot5A:0.9 | 3zqtA-3ot5A:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p8c | ABL INTERACTOR 2 (Homo sapiens) |
PF07815(Abi_HHR) | 4 | PRO F 13GLY F 15LEU F 68ASN F 71 | None | 0.86A | 3zqtA-3p8cF:undetectable | 3zqtA-3p8cF:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pam | TRANSMEMBRANEPROTEIN (Bartonellahenselae) |
PF00496(SBP_bac_5) | 4 | PRO A 505GLY A 506ASN A 507LEU A 542 | None | 0.99A | 3zqtA-3pamA:undetectable | 3zqtA-3pamA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sfz | APOPTOTIC PEPTIDASEACTIVATING FACTOR 1 (Mus musculus) |
PF00400(WD40)PF00931(NB-ARC)PF12894(ANAPC4_WD40) | 4 | PRO A 147GLY A 148LEU A 143ASN A 144 | None | 1.02A | 3zqtA-3sfzA:undetectable | 3zqtA-3sfzA:11.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u2p | RECEPTORTYROSINE-PROTEINKINASE ERBB-4 (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain) | 4 | GLY A 82ASN A 119LEU A 85GLU A 8 | None | 0.90A | 3zqtA-3u2pA:undetectable | 3zqtA-3u2pA:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u7u | RECEPTORTYROSINE-PROTEINKINASE ERBB-4 (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 4 | GLY A 82ASN A 119LEU A 85GLU A 8 | None | 0.95A | 3zqtA-3u7uA:undetectable | 3zqtA-3u7uA:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3um6 | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Plasmodiumfalciparum) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 4 | GLY A 393ASN A 424LEU A 397ASN A 398 | None | 0.99A | 3zqtA-3um6A:undetectable | 3zqtA-3um6A:17.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vss | BETA-FRUCTOFURANOSIDASE (Microbacteriumsaccharophilum) |
PF02435(Glyco_hydro_68) | 4 | PRO A 451GLY A 452ASN A 85GLU A 84 | None | 0.94A | 3zqtA-3vssA:undetectable | 3zqtA-3vssA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbx | PUTATIVE2,5-DIKETO-D-GLUCONIC ACID REDUCTASE (Gluconobacteroxydans) |
PF00248(Aldo_ket_red) | 4 | PRO A 116ASN A 82ASN A 144GLU A 146 | None | 0.98A | 3zqtA-3wbxA:undetectable | 3zqtA-3wbxA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2l | TWO-COMPONENT SYSTEMSENSOR HISTIDINEKINASE/RESPONSE (Bacteroidesthetaiotaomicron) |
PF07494(Reg_prop)PF07495(Y_Y_Y) | 4 | GLY A 563ASN A 586LEU A 583ASN A 581 | None | 0.92A | 3zqtA-4a2lA:undetectable | 3zqtA-4a2lA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dcm | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE G (Escherichiacoli) |
PF05175(MTS) | 4 | GLY A 56ASN A 83LEU A 13GLU A 29 | None | 1.00A | 3zqtA-4dcmA:undetectable | 3zqtA-4dcmA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dhx | ENHANCER OF YELLOW 2TRANSCRIPTION FACTORHOMOLOG (Homo sapiens) |
PF10163(EnY2) | 4 | PRO B 73GLY B 75LEU B 46GLU B 70 | None | 0.97A | 3zqtA-4dhxB:undetectable | 3zqtA-4dhxB:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4elj | RETINOBLASTOMA-ASSOCIATED PROTEIN (Homo sapiens) |
PF01857(RB_B)PF01858(RB_A)PF11934(DUF3452) | 4 | GLY A 100LEU A 120ASN A 123GLU A 125 | None | 0.89A | 3zqtA-4eljA:undetectable | 3zqtA-4eljA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jb1 | UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINEREDUCTASE (Pseudomonasaeruginosa) |
PF01565(FAD_binding_4)PF02873(MurB_C) | 4 | PRO A 231GLY A 235ASN A 304ASN A 15 | FAD A 401 ( 4.7A)NoneNoneNone | 0.91A | 3zqtA-4jb1A:undetectable | 3zqtA-4jb1A:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jfn | AMYLOID BETA A4PROTEIN (Homo sapiens) |
PF02177(APP_N) | 4 | PRO A 56GLY A 58LEU A 41ASN A 42 | None | 0.94A | 3zqtA-4jfnA:undetectable | 3zqtA-4jfnA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kyq | PHOSPHOGLUCANPHOSPHATASE LSF2,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00782(DSPc) | 4 | PRO A 201GLY A 202LEU A 167ASN A 232 | None | 0.82A | 3zqtA-4kyqA:undetectable | 3zqtA-4kyqA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mr0 | PLASMIN ANDFIBRONECTIN-BINDINGPROTEIN A (Streptococcuspneumoniae) |
PF12708(Pectate_lyase_3)PF13229(Beta_helix) | 4 | GLY A 219ASN A 218LEU A 273ASN A 272 | None | 0.97A | 3zqtA-4mr0A:undetectable | 3zqtA-4mr0A:17.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mtl | PROTEIN-LYSINEMETHYLTRANSFERASEMETTL21C (Homo sapiens) |
PF10294(Methyltransf_16) | 4 | GLY A 173LEU A 176ASN A 179GLU A 169 | None | 0.99A | 3zqtA-4mtlA:undetectable | 3zqtA-4mtlA:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nqz | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] FABI (Pseudomonasaeruginosa) |
PF13561(adh_short_C2) | 4 | GLY A 232LEU A 145ASN A 188GLU A 246 | None | 0.90A | 3zqtA-4nqzA:undetectable | 3zqtA-4nqzA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4okd | ISOAMYLASE (Chlamydomonasreinhardtii) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 4 | PRO A 184GLY A 185ASN A 400LEU A 406 | None | 1.00A | 3zqtA-4okdA:undetectable | 3zqtA-4okdA:14.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ony | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 5 (Brucellamelitensis) |
PF00496(SBP_bac_5) | 4 | PRO A 495GLY A 496ASN A 497LEU A 532 | CL A 601 ( 4.5A)NoneNoneNone | 0.94A | 3zqtA-4onyA:undetectable | 3zqtA-4onyA:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q4a | UNCHARACTERIZED ABCTRANSPORTERATP-BINDING PROTEINTM_0288 (Thermotogamaritima) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 4 | GLY B 213ASN B 216ASN B 208GLU B 207 | None | 1.02A | 3zqtA-4q4aB:undetectable | 3zqtA-4q4aB:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r86 | RND FAMILYAMINOGLYCOSIDE/MULTIDRUG EFFLUX PUMP (Salmonellaenterica) |
PF00873(ACR_tran) | 4 | GLY A 137ASN A 136ASN A 264GLU A 265 | None | 1.01A | 3zqtA-4r86A:undetectable | 3zqtA-4r86A:22.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4udb | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 4 | PRO A 788GLY A 789ASN A 898GLU A 902 | None | 0.56A | 3zqtA-4udbA:33.9 | 3zqtA-4udbA:49.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wpx | CELL DIVISIONCONTROL PROTEIN31-LIKE PROTEIN (Chaetomiumthermophilum) |
PF00036(EF-hand_1)PF13499(EF-hand_7) | 4 | GLY A 101LEU A 20ASN A 18GLU A 15 | None | 1.01A | 3zqtA-4wpxA:undetectable | 3zqtA-4wpxA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xfk | PUTATIVE BRANCHEDCHAIN AMINO ACID ABCTRANSPORTER,PERIPLASMIC AMINOACID-BINDING PROTEIN (Brucella ovis) |
PF13458(Peripla_BP_6) | 4 | PRO A 321GLY A 322ASN A 326LEU A 298 | None | 0.90A | 3zqtA-4xfkA:undetectable | 3zqtA-4xfkA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y63 | HISTO-BLOOD GROUPABO SYSTEMTRANSFERASE (Homo sapiens) |
PF03414(Glyco_transf_6) | 4 | GLY A 230LEU A 310ASN A 307GLU A 303 | NoneNoneNoneBHE A 401 (-2.6A) | 0.99A | 3zqtA-4y63A:undetectable | 3zqtA-4y63A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z5y | COENZYME PQQSYNTHESIS PROTEIN B (Pseudomonasputida) |
PF12706(Lactamase_B_2) | 4 | PRO A 198GLY A 199LEU A 161ASN A 180 | None | 1.02A | 3zqtA-4z5yA:undetectable | 3zqtA-4z5yA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxl | O-GLCNACASE NAGJ (Clostridiumperfringens) |
PF02838(Glyco_hydro_20b)PF07555(NAGidase) | 4 | PRO A 368GLY A 369ASN A 373GLU A 374 | None | 0.77A | 3zqtA-4zxlA:undetectable | 3zqtA-4zxlA:18.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ex6 | CYTOCHROME P450 (Streptomycestoyocaensis) |
no annotation | 4 | PRO C 105GLY C 106LEU C 209GLU C 216 | None | 1.01A | 3zqtA-5ex6C:undetectable | 3zqtA-5ex6C:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5icq | METHYLOCYSTIS PARVUSOBBP MBNE (Methylocystisparvus) |
PF00496(SBP_bac_5) | 4 | PRO A 505GLY A 506ASN A 507LEU A 542 | None | 0.91A | 3zqtA-5icqA:undetectable | 3zqtA-5icqA:15.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jp0 | BETA-GLUCOSIDASEBOGH3B (Bacteroidesovatus) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | PRO A 490GLY A 441LEU A 551GLU A 509 | None | 0.90A | 3zqtA-5jp0A:undetectable | 3zqtA-5jp0A:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jsy | PERIPLASMIC [NIFESE]HYDROGENASE, SMALLSUBUNIT (Desulfovibriovulgaris) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | PRO A 110GLY A 109LEU A 144ASN A 147 | None | 0.98A | 3zqtA-5jsyA:undetectable | 3zqtA-5jsyA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k3j | ACYL-COENZYME AOXIDASE (Caenorhabditiselegans) |
PF01756(ACOX)PF02770(Acyl-CoA_dh_M)PF14749(Acyl-CoA_ox_N) | 4 | PRO A 213GLY A 212ASN A 210ASN A 160 | None | 1.02A | 3zqtA-5k3jA:undetectable | 3zqtA-5k3jA:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kbp | GLYCOSYL HYDROLASE,FAMILY 38 (Enterococcusfaecalis) |
PF01074(Glyco_hydro_38)PF07748(Glyco_hydro_38C)PF09261(Alpha-mann_mid) | 4 | GLY A 827LEU A 847ASN A 846GLU A 888 | None | 0.99A | 3zqtA-5kbpA:undetectable | 3zqtA-5kbpA:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mpq | TRANSGLYCOSYLASE (Neisseriameningitidis) |
PF01464(SLT)PF14718(SLT_L) | 4 | GLY A 526LEU A 516ASN A 519GLU A 520 | None | 0.99A | 3zqtA-5mpqA:undetectable | 3zqtA-5mpqA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mwp | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
no annotation | 5 | PRO A 788GLY A 789ASN A 792ASN A 898GLU A 902 | None | 1.07A | 3zqtA-5mwpA:37.2 | 3zqtA-5mwpA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n28 | METHYL-COENZYME MREDUCTASE SUBUNITALPHA (Methanotorrisformicicus) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 4 | PRO A 281GLY A 282ASN A 476LEU A 270 | NoneNoneAGM A 274 ( 3.6A)AGM A 274 ( 3.8A) | 0.84A | 3zqtA-5n28A:undetectable | 3zqtA-5n28A:16.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nz7 | CELLODEXTRINPHOSPHORYLASE (Ruminiclostridiumthermocellum) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 4 | GLY A 23ASN A 19LEU A 28ASN A 27 | None | 0.90A | 3zqtA-5nz7A:undetectable | 3zqtA-5nz7A:13.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ols | RHAMNOGALACTURONANLYASE (Bacteroidesthetaiotaomicron) |
no annotation | 4 | GLY A 133LEU A 136ASN A 135GLU A 95 | None | 1.01A | 3zqtA-5olsA:undetectable | 3zqtA-5olsA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ot4 | INTERAPTIN (Legionellapneumophila) |
no annotation | 4 | GLY A 293ASN A 296ASN A 284GLU A 287 | None | 0.96A | 3zqtA-5ot4A:undetectable | 3zqtA-5ot4A:14.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u0l | N-SUCCINYLGLUTAMATE5-SEMIALDEHYDEDEHYDROGENASE (Marinobacterhydrocarbonoclasticus) |
PF00171(Aldedh) | 4 | GLY A 410ASN A 432LEU A 437ASN A 253 | None | 1.01A | 3zqtA-5u0lA:undetectable | 3zqtA-5u0lA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b0n | ENVELOPEGLYCOPROTEIN GP140 (Humanimmunodeficiencyvirus 1) |
no annotation | 4 | PRO G 43GLY G 41LEU G 544ASN G 543 | None | 0.99A | 3zqtA-6b0nG:undetectable | 3zqtA-6b0nG:13.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c43 | GAMMA-AMINOBUTYRALDEHYDE DEHYDROGENASE (Salmonellaenterica) |
no annotation | 4 | PRO A 194GLY A 195ASN A 198ASN A 50 | None | 1.01A | 3zqtA-6c43A:undetectable | 3zqtA-6c43A:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f9n | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTORSUBUNIT 1PRE-MRNA 3' ENDPROCESSING PROTEINWDR33 (Homo sapiens) |
no annotation | 4 | PRO A 228GLY A 229ASN B 405ASN B 104 | None | 0.91A | 3zqtA-6f9nA:undetectable | 3zqtA-6f9nA:14.00 |