SIMILAR PATTERNS OF AMINO ACIDS FOR 3ZQT_A_30ZA1920

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ab6 CHEMOTAXIS PROTEIN
CHEY


(Escherichia
coli)
PF00072
(Response_reg)
4 GLY A  52
LEU A   6
ASN A  32
GLU A  34
None
0.97A 3zqtA-1ab6A:
undetectable
3zqtA-1ab6A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1as4 ANTICHYMOTRYPSIN

(Homo sapiens)
PF00079
(Serpin)
4 GLY A 139
ASN A 116
LEU A 100
ASN A 104
None
1.02A 3zqtA-1as4A:
0.0
3zqtA-1as4A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b0k PROTEIN (ACONITASE)

(Sus scrofa)
PF00330
(Aconitase)
PF00694
(Aconitase_C)
5 PRO A 243
GLY A 244
LEU A 315
ASN A 314
GLU A 312
None
1.44A 3zqtA-1b0kA:
0.0
3zqtA-1b0kA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b0k PROTEIN (ACONITASE)

(Sus scrofa)
PF00330
(Aconitase)
PF00694
(Aconitase_C)
4 PRO A 325
GLY A 324
ASN A 323
GLU A 344
None
0.98A 3zqtA-1b0kA:
0.0
3zqtA-1b0kA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)


(Streptomyces
griseus)
no annotation 4 PRO A 317
LEU A 294
ASN A 314
GLU A 309
None
1.03A 3zqtA-1bwdA:
0.0
3zqtA-1bwdA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6y METHYL-COENZYME M
REDUCTASE SUBUNIT
ALPHA


(Methanosarcina
barkeri)
PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N)
4 PRO A1292
GLY A1293
ASN A1494
LEU A1281
None
None
AGM  A1285 ( 3.7A)
AGM  A1285 ( 3.8A)
0.81A 3zqtA-1e6yA:
0.0
3zqtA-1e6yA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eav MOLYBDOPTERIN
BIOSYNTHESIS CNX1
PROTEIN


(Arabidopsis
thaliana)
PF00994
(MoCF_biosynth)
4 PRO A 138
GLY A 139
ASN A 142
GLU A 146
None
1.01A 3zqtA-1eavA:
0.0
3zqtA-1eavA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1exe TRANSCRIPTION FACTOR
1


(Bacillus virus
SPO1)
PF00216
(Bac_DNA_binding)
4 PRO A  81
GLY A  82
LEU A  48
ASN A  49
None
1.00A 3zqtA-1exeA:
undetectable
3zqtA-1exeA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g01 ENDOGLUCANASE

(Bacillus sp.
KSM-635)
PF00150
(Cellulase)
PF03424
(CBM_17_28)
4 PRO A 338
GLY A 336
ASN A 377
ASN A 372
None
None
None
CD  A 591 ( 4.8A)
0.84A 3zqtA-1g01A:
undetectable
3zqtA-1g01A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8k ARSENITE OXIDASE

(Alcaligenes
faecalis)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
4 PRO A 303
GLY A 304
ASN A 391
LEU A 683
None
MGD  A5002 (-3.6A)
None
None
0.87A 3zqtA-1g8kA:
0.0
3zqtA-1g8kA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3j BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE


(Plasmodium
falciparum)
PF00303
(Thymidylat_synt)
4 GLY C 393
ASN C 424
LEU C 397
ASN C 398
None
1.01A 3zqtA-1j3jC:
0.0
3zqtA-1j3jC:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jig DLP-2

(Bacillus
anthracis)
PF00210
(Ferritin)
4 PRO A  69
GLY A  67
LEU A  65
GLU A  60
None
None
None
FE  A 402 (-2.4A)
0.98A 3zqtA-1jigA:
undetectable
3zqtA-1jigA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1la2 MYO-INOSITOL-1-PHOSP
HATE SYNTHASE


(Saccharomyces
cerevisiae)
PF01658
(Inos-1-P_synth)
PF07994
(NAD_binding_5)
4 PRO A 303
GLY A 304
LEU A 264
ASN A 263
None
0.96A 3zqtA-1la2A:
undetectable
3zqtA-1la2A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mro METHYL-COENZYME M
REDUCTASE


(Methanothermobacter
marburgensis)
PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N)
4 PRO A 278
GLY A 279
ASN A 474
LEU A 267
None
None
AGM  A 271 ( 3.7A)
AGM  A 271 ( 3.8A)
0.79A 3zqtA-1mroA:
undetectable
3zqtA-1mroA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mwp AMYLOID A4 PROTEIN

(Homo sapiens)
PF02177
(APP_N)
4 PRO A  56
GLY A  58
LEU A  41
ASN A  42
None
0.92A 3zqtA-1mwpA:
undetectable
3zqtA-1mwpA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n31 L-CYSTEINE/CYSTINE
LYASE C-DES


(Synechocystis
sp. PCC 6714)
PF00266
(Aminotran_5)
4 GLY A 315
LEU A 385
ASN A 382
GLU A 378
None
0.98A 3zqtA-1n31A:
undetectable
3zqtA-1n31A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nne DNA MISMATCH REPAIR
PROTEIN MUTS


(Thermus
aquaticus)
PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III)
4 PRO A  69
GLY A  44
LEU A   5
GLU A   8
None
0.97A 3zqtA-1nneA:
undetectable
3zqtA-1nneA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT


(Candida
albicans)
PF01331
(mRNA_cap_enzyme)
PF03919
(mRNA_cap_C)
4 PRO A  13
GLY A  14
ASN A  15
ASN A 101
None
1.01A 3zqtA-1p16A:
undetectable
3zqtA-1p16A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r82 GLYCOPROTEIN-FUCOSYL
GALACTOSIDE
ALPHA-GALACTOSYLTRAN
SFERASE


(Homo sapiens)
PF03414
(Glyco_transf_6)
4 GLY A 230
LEU A 310
ASN A 307
GLU A 303
None
None
None
AOG  A 452 (-2.6A)
1.00A 3zqtA-1r82A:
undetectable
3zqtA-1r82A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s4d UROPORPHYRIN-III
C-METHYLTRANSFERASE


(Pseudomonas
denitrificans
(nomen
rejiciendum))
PF00590
(TP_methylase)
4 PRO A  24
GLY A  25
ASN A  51
ASN A 212
SAH  A1501 (-4.9A)
None
None
None
0.98A 3zqtA-1s4dA:
undetectable
3zqtA-1s4dA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1upf URACIL
PHOSPHORIBOSYLTRANSF
ERASE


(Toxoplasma
gondii)
no annotation 4 PRO D 231
GLY D 232
LEU D 196
GLU D  22
None
1.00A 3zqtA-1upfD:
undetectable
3zqtA-1upfD:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbl PECTATE LYASE 47

(Bacillus sp.
TS-47)
PF00544
(Pec_lyase_C)
4 PRO A 177
GLY A 183
ASN A 186
GLU A 174
None
1.02A 3zqtA-1vblA:
undetectable
3zqtA-1vblA:
21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ax9 ANDROGEN RECEPTOR

(Homo sapiens)
PF00104
(Hormone_recep)
5 PRO A 723
GLY A 724
ASN A 727
LEU A 830
ASN A 833
None
1.00A 3zqtA-2ax9A:
40.4
3zqtA-2ax9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ax9 ANDROGEN RECEPTOR

(Homo sapiens)
PF00104
(Hormone_recep)
5 PRO A 723
GLY A 724
LEU A 830
ASN A 833
GLU A 837
None
0.55A 3zqtA-2ax9A:
40.4
3zqtA-2ax9A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3t FATTY OXIDATION
COMPLEX ALPHA
SUBUNIT


(Pseudomonas
fragi)
PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N)
4 PRO A 496
GLY A 497
ASN A 501
GLU A 558
None
1.01A 3zqtA-2d3tA:
undetectable
3zqtA-2d3tA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2diw PUTATIVE RNA-BINDING
PROTEIN 16


(Homo sapiens)
PF04818
(CTD_bind)
4 PRO A  70
GLY A  71
LEU A 108
GLU A  66
None
1.02A 3zqtA-2diwA:
undetectable
3zqtA-2diwA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE


(Ensifer
adhaerens)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
4 PRO A 167
GLY A 170
ASN A  73
LEU A 175
None
None
NDP  A1500 (-3.4A)
None
1.00A 3zqtA-2glxA:
undetectable
3zqtA-2glxA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix8 ELONGATION FACTOR 3A

(Saccharomyces
cerevisiae)
PF00005
(ABC_tran)
4 PRO A1291
GLY A1292
ASN A1296
LEU A1254
None
0.89A 3zqtA-2ix8A:
undetectable
3zqtA-2ix8A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lf2 UNCHARACTERIZED
PROTEIN


(Cytophaga
hutchinsonii)
PF08327
(AHSA1)
4 PRO A 110
LEU A 105
ASN A 106
GLU A 108
None
0.74A 3zqtA-2lf2A:
undetectable
3zqtA-2lf2A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbr URIDINE
DIPHOSPHO-N-ACETYLEN
OLPYRUVYLGLUCOSAMINE
REDUCTASE


(Escherichia
coli)
PF01565
(FAD_binding_4)
PF02873
(MurB_C)
4 PRO A 221
GLY A 225
ASN A 294
ASN A   9
FAD  A 401 ( 4.9A)
None
None
None
1.02A 3zqtA-2mbrA:
undetectable
3zqtA-2mbrA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n3s TRANSLATION
INITIATION FACTOR
IF-1


(Burkholderia
thailandensis)
PF01176
(eIF-1a)
4 GLY A  29
ASN A  28
LEU A  26
GLU A  12
None
0.97A 3zqtA-2n3sA:
undetectable
3zqtA-2n3sA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA


(Homo sapiens)
PF00899
(ThiF)
PF08825
(E2_bind)
PF13416
(SBP_bac_8)
4 PRO B2171
LEU B2162
ASN B2163
GLU B2165
None
0.99A 3zqtA-2nvuB:
undetectable
3zqtA-2nvuB:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nya PERIPLASMIC NITRATE
REDUCTASE


(Escherichia
coli)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
4 GLY A 108
ASN A 135
LEU A 437
ASN A 438
None
0.96A 3zqtA-2nyaA:
undetectable
3zqtA-2nyaA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p58 PUTATIVE TYPE III
SECRETION PROTEIN
YSCG


(Yersinia pestis)
PF09477
(Type_III_YscG)
4 GLY C  62
ASN C  63
LEU C  74
GLU C  39
None
0.87A 3zqtA-2p58C:
undetectable
3zqtA-2p58C:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pd3 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]


(Helicobacter
pylori)
PF13561
(adh_short_C2)
4 GLY A 228
LEU A 141
ASN A 184
GLU A 242
None
0.83A 3zqtA-2pd3A:
undetectable
3zqtA-2pd3A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ps2 PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME


(Aspergillus
oryzae)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 PRO A 173
GLY A 171
LEU A 201
GLU A 204
None
0.93A 3zqtA-2ps2A:
undetectable
3zqtA-2ps2A:
23.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2q3y ANCESTRAL CORTICIOD
RECEPTOR


(unidentified)
PF00104
(Hormone_recep)
4 PRO A  51
GLY A  52
ASN A 161
GLU A 165
None
0.88A 3zqtA-2q3yA:
37.4
3zqtA-2q3yA:
58.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qdj RETINOBLASTOMA-ASSOC
IATED PROTEIN


(Homo sapiens)
PF11934
(DUF3452)
4 GLY A 100
LEU A 120
ASN A 123
GLU A 125
None
0.75A 3zqtA-2qdjA:
undetectable
3zqtA-2qdjA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5d O-GLCNACASE NAGJ

(Clostridium
perfringens)
PF00754
(F5_F8_type_C)
PF02838
(Glyco_hydro_20b)
PF07555
(NAGidase)
4 PRO A 368
GLY A 369
ASN A 373
GLU A 374
None
0.65A 3zqtA-2v5dA:
undetectable
3zqtA-2v5dA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xax RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
SUBUNIT ALPHA


(Escherichia
coli)
PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone)
4 PRO A 673
GLY A 674
ASN A 675
GLU A 671
None
0.80A 3zqtA-2xaxA:
undetectable
3zqtA-2xaxA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y7d 3-KETO-5-AMINOHEXANO
ATE CLEAVAGE ENZYME


(Candidatus
Cloacimonas
acidaminovorans)
PF05853
(BKACE)
4 PRO A 176
GLY A 178
LEU A 112
ASN A 113
None
0.97A 3zqtA-2y7dA:
undetectable
3zqtA-2y7dA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yev CYTOCHROME C OXIDASE
POLYPEPTIDE I+III


(Thermus
thermophilus)
PF00115
(COX1)
PF00510
(COX3)
4 GLY A 235
LEU A 724
ASN A 723
GLU A 722
None
0.98A 3zqtA-2yevA:
undetectable
3zqtA-2yevA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yia RNA-DIRECTED RNA
POLYMERASE


(Infectious
pancreatic
necrosis virus)
PF04197
(Birna_RdRp)
4 PRO A 141
GLY A 143
LEU A 135
ASN A 138
None
0.83A 3zqtA-2yiaA:
undetectable
3zqtA-2yiaA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yib RNA-DIRECTED RNA
POLYMERASE


(Infectious
pancreatic
necrosis virus)
PF04197
(Birna_RdRp)
4 PRO D 141
GLY D 143
LEU D 135
ASN D 138
None
0.83A 3zqtA-2yibD:
undetectable
3zqtA-2yibD:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3be8 NEUROLIGIN-4,
X-LINKED


(Homo sapiens)
PF00135
(COesterase)
4 GLY A  68
LEU A  62
ASN A  64
GLU A  65
NA  A 626 ( 4.8A)
None
None
None
0.96A 3zqtA-3be8A:
undetectable
3zqtA-3be8A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ejh COLLAGEN TYPE-I A1
CHAIN
FIBRONECTIN


(Homo sapiens)
PF00039
(fn1)
no annotation
4 PRO E 964
GLY E 965
LEU A 541
GLU A 537
None
0.88A 3zqtA-3ejhE:
undetectable
3zqtA-3ejhE:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ek2 ENOYL-(ACYL-CARRIER-
PROTEIN) REDUCTASE
(NADH)


(Burkholderia
pseudomallei)
PF13561
(adh_short_C2)
4 GLY A 229
LEU A 142
ASN A 185
GLU A 243
None
0.86A 3zqtA-3ek2A:
undetectable
3zqtA-3ek2A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxi TOLL-LIKE RECEPTOR 4

(Homo sapiens)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 PRO A 489
LEU A 508
ASN A 486
GLU A 485
None
0.83A 3zqtA-3fxiA:
undetectable
3zqtA-3fxiA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3grk ENOYL-(ACYL-CARRIER-
PROTEIN) REDUCTASE
(NADH)


(Brucella
melitensis)
PF13561
(adh_short_C2)
4 GLY A 232
LEU A 145
ASN A 188
GLU A 246
None
0.92A 3zqtA-3grkA:
undetectable
3zqtA-3grkA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ju8 SUCCINYLGLUTAMIC
SEMIALDEHYDE
DEHYDROGENASE


(Pseudomonas
aeruginosa)
PF00171
(Aldedh)
4 GLY A 408
ASN A 430
LEU A 435
ASN A 250
None
0.98A 3zqtA-3ju8A:
undetectable
3zqtA-3ju8A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ktm AMYLOID BETA A4
PROTEIN


(Homo sapiens)
PF02177
(APP_N)
PF12924
(APP_Cu_bd)
4 PRO A  56
GLY A  58
LEU A  41
ASN A  42
None
0.99A 3zqtA-3ktmA:
undetectable
3zqtA-3ktmA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lkd TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT


(Streptococcus
thermophilus)
PF02384
(N6_Mtase)
PF12161
(HsdM_N)
4 GLY A 233
ASN A 267
LEU A 237
ASN A 238
None
1.01A 3zqtA-3lkdA:
undetectable
3zqtA-3lkdA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lvu ABC TRANSPORTER,
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN


(Ruegeria
pomeroyi)
PF00496
(SBP_bac_5)
4 PRO A 501
GLY A 502
ASN A 503
LEU A 538
None
0.84A 3zqtA-3lvuA:
undetectable
3zqtA-3lvuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE


(Escherichia
coli)
PF00725
(3HCDH)
PF02737
(3HCDH_N)
4 PRO A 386
GLY A 387
LEU A 444
ASN A 447
None
0.93A 3zqtA-3mogA:
undetectable
3zqtA-3mogA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o5a PERIPLASMIC NITRATE
REDUCTASE


(Cupriavidus
necator)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
4 GLY A 117
ASN A 144
LEU A 447
ASN A 448
None
0.90A 3zqtA-3o5aA:
undetectable
3zqtA-3o5aA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE


(Listeria
monocytogenes)
PF02350
(Epimerase_2)
4 PRO A 293
GLY A 294
LEU A 181
GLU A 290
None
PGE  A 381 (-4.8A)
PGE  A 381 ( 4.6A)
None
0.97A 3zqtA-3ot5A:
0.9
3zqtA-3ot5A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8c ABL INTERACTOR 2

(Homo sapiens)
PF07815
(Abi_HHR)
4 PRO F  13
GLY F  15
LEU F  68
ASN F  71
None
0.86A 3zqtA-3p8cF:
undetectable
3zqtA-3p8cF:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pam TRANSMEMBRANE
PROTEIN


(Bartonella
henselae)
PF00496
(SBP_bac_5)
4 PRO A 505
GLY A 506
ASN A 507
LEU A 542
None
0.99A 3zqtA-3pamA:
undetectable
3zqtA-3pamA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfz APOPTOTIC PEPTIDASE
ACTIVATING FACTOR 1


(Mus musculus)
PF00400
(WD40)
PF00931
(NB-ARC)
PF12894
(ANAPC4_WD40)
4 PRO A 147
GLY A 148
LEU A 143
ASN A 144
None
1.02A 3zqtA-3sfzA:
undetectable
3zqtA-3sfzA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4


(Homo sapiens)
PF00757
(Furin-like)
PF01030
(Recep_L_domain)
4 GLY A  82
ASN A 119
LEU A  85
GLU A   8
None
0.90A 3zqtA-3u2pA:
undetectable
3zqtA-3u2pA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u7u RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4


(Homo sapiens)
PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV)
4 GLY A  82
ASN A 119
LEU A  85
GLU A   8
None
0.95A 3zqtA-3u7uA:
undetectable
3zqtA-3u7uA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3um6 BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE


(Plasmodium
falciparum)
PF00186
(DHFR_1)
PF00303
(Thymidylat_synt)
4 GLY A 393
ASN A 424
LEU A 397
ASN A 398
None
0.99A 3zqtA-3um6A:
undetectable
3zqtA-3um6A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vss BETA-FRUCTOFURANOSID
ASE


(Microbacterium
saccharophilum)
PF02435
(Glyco_hydro_68)
4 PRO A 451
GLY A 452
ASN A  85
GLU A  84
None
0.94A 3zqtA-3vssA:
undetectable
3zqtA-3vssA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE


(Gluconobacter
oxydans)
PF00248
(Aldo_ket_red)
4 PRO A 116
ASN A  82
ASN A 144
GLU A 146
None
0.98A 3zqtA-3wbxA:
undetectable
3zqtA-3wbxA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2l TWO-COMPONENT SYSTEM
SENSOR HISTIDINE
KINASE/RESPONSE


(Bacteroides
thetaiotaomicron)
PF07494
(Reg_prop)
PF07495
(Y_Y_Y)
4 GLY A 563
ASN A 586
LEU A 583
ASN A 581
None
0.92A 3zqtA-4a2lA:
undetectable
3zqtA-4a2lA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dcm RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G


(Escherichia
coli)
PF05175
(MTS)
4 GLY A  56
ASN A  83
LEU A  13
GLU A  29
None
1.00A 3zqtA-4dcmA:
undetectable
3zqtA-4dcmA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dhx ENHANCER OF YELLOW 2
TRANSCRIPTION FACTOR
HOMOLOG


(Homo sapiens)
PF10163
(EnY2)
4 PRO B  73
GLY B  75
LEU B  46
GLU B  70
None
0.97A 3zqtA-4dhxB:
undetectable
3zqtA-4dhxB:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4elj RETINOBLASTOMA-ASSOC
IATED PROTEIN


(Homo sapiens)
PF01857
(RB_B)
PF01858
(RB_A)
PF11934
(DUF3452)
4 GLY A 100
LEU A 120
ASN A 123
GLU A 125
None
0.89A 3zqtA-4eljA:
undetectable
3zqtA-4eljA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jb1 UDP-N-ACETYLENOLPYRU
VOYLGLUCOSAMINE
REDUCTASE


(Pseudomonas
aeruginosa)
PF01565
(FAD_binding_4)
PF02873
(MurB_C)
4 PRO A 231
GLY A 235
ASN A 304
ASN A  15
FAD  A 401 ( 4.7A)
None
None
None
0.91A 3zqtA-4jb1A:
undetectable
3zqtA-4jb1A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jfn AMYLOID BETA A4
PROTEIN


(Homo sapiens)
PF02177
(APP_N)
4 PRO A  56
GLY A  58
LEU A  41
ASN A  42
None
0.94A 3zqtA-4jfnA:
undetectable
3zqtA-4jfnA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kyq PHOSPHOGLUCAN
PHOSPHATASE LSF2,
CHLOROPLASTIC


(Arabidopsis
thaliana)
PF00782
(DSPc)
4 PRO A 201
GLY A 202
LEU A 167
ASN A 232
None
0.82A 3zqtA-4kyqA:
undetectable
3zqtA-4kyqA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mr0 PLASMIN AND
FIBRONECTIN-BINDING
PROTEIN A


(Streptococcus
pneumoniae)
PF12708
(Pectate_lyase_3)
PF13229
(Beta_helix)
4 GLY A 219
ASN A 218
LEU A 273
ASN A 272
None
0.97A 3zqtA-4mr0A:
undetectable
3zqtA-4mr0A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mtl PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21C


(Homo sapiens)
PF10294
(Methyltransf_16)
4 GLY A 173
LEU A 176
ASN A 179
GLU A 169
None
0.99A 3zqtA-4mtlA:
undetectable
3zqtA-4mtlA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nqz ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH] FABI


(Pseudomonas
aeruginosa)
PF13561
(adh_short_C2)
4 GLY A 232
LEU A 145
ASN A 188
GLU A 246
None
0.90A 3zqtA-4nqzA:
undetectable
3zqtA-4nqzA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4okd ISOAMYLASE

(Chlamydomonas
reinhardtii)
PF00128
(Alpha-amylase)
PF02922
(CBM_48)
4 PRO A 184
GLY A 185
ASN A 400
LEU A 406
None
1.00A 3zqtA-4okdA:
undetectable
3zqtA-4okdA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ony EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 5


(Brucella
melitensis)
PF00496
(SBP_bac_5)
4 PRO A 495
GLY A 496
ASN A 497
LEU A 532
CL  A 601 ( 4.5A)
None
None
None
0.94A 3zqtA-4onyA:
undetectable
3zqtA-4onyA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4a UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288


(Thermotoga
maritima)
PF00005
(ABC_tran)
PF00664
(ABC_membrane)
4 GLY B 213
ASN B 216
ASN B 208
GLU B 207
None
1.02A 3zqtA-4q4aB:
undetectable
3zqtA-4q4aB:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r86 RND FAMILY
AMINOGLYCOSIDE/MULTI
DRUG EFFLUX PUMP


(Salmonella
enterica)
PF00873
(ACR_tran)
4 GLY A 137
ASN A 136
ASN A 264
GLU A 265
None
1.01A 3zqtA-4r86A:
undetectable
3zqtA-4r86A:
22.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4udb MINERALOCORTICOID
RECEPTOR


(Homo sapiens)
PF00104
(Hormone_recep)
4 PRO A 788
GLY A 789
ASN A 898
GLU A 902
None
0.56A 3zqtA-4udbA:
33.9
3zqtA-4udbA:
49.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wpx CELL DIVISION
CONTROL PROTEIN
31-LIKE PROTEIN


(Chaetomium
thermophilum)
PF00036
(EF-hand_1)
PF13499
(EF-hand_7)
4 GLY A 101
LEU A  20
ASN A  18
GLU A  15
None
1.01A 3zqtA-4wpxA:
undetectable
3zqtA-4wpxA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xfk PUTATIVE BRANCHED
CHAIN AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN


(Brucella ovis)
PF13458
(Peripla_BP_6)
4 PRO A 321
GLY A 322
ASN A 326
LEU A 298
None
0.90A 3zqtA-4xfkA:
undetectable
3zqtA-4xfkA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y63 HISTO-BLOOD GROUP
ABO SYSTEM
TRANSFERASE


(Homo sapiens)
PF03414
(Glyco_transf_6)
4 GLY A 230
LEU A 310
ASN A 307
GLU A 303
None
None
None
BHE  A 401 (-2.6A)
0.99A 3zqtA-4y63A:
undetectable
3zqtA-4y63A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z5y COENZYME PQQ
SYNTHESIS PROTEIN B


(Pseudomonas
putida)
PF12706
(Lactamase_B_2)
4 PRO A 198
GLY A 199
LEU A 161
ASN A 180
None
1.02A 3zqtA-4z5yA:
undetectable
3zqtA-4z5yA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxl O-GLCNACASE NAGJ

(Clostridium
perfringens)
PF02838
(Glyco_hydro_20b)
PF07555
(NAGidase)
4 PRO A 368
GLY A 369
ASN A 373
GLU A 374
None
0.77A 3zqtA-4zxlA:
undetectable
3zqtA-4zxlA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ex6 CYTOCHROME P450

(Streptomyces
toyocaensis)
no annotation 4 PRO C 105
GLY C 106
LEU C 209
GLU C 216
None
1.01A 3zqtA-5ex6C:
undetectable
3zqtA-5ex6C:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5icq METHYLOCYSTIS PARVUS
OBBP MBNE


(Methylocystis
parvus)
PF00496
(SBP_bac_5)
4 PRO A 505
GLY A 506
ASN A 507
LEU A 542
None
0.91A 3zqtA-5icqA:
undetectable
3zqtA-5icqA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jp0 BETA-GLUCOSIDASE
BOGH3B


(Bacteroides
ovatus)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like)
4 PRO A 490
GLY A 441
LEU A 551
GLU A 509
None
0.90A 3zqtA-5jp0A:
undetectable
3zqtA-5jp0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jsy PERIPLASMIC [NIFESE]
HYDROGENASE, SMALL
SUBUNIT


(Desulfovibrio
vulgaris)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
4 PRO A 110
GLY A 109
LEU A 144
ASN A 147
None
0.98A 3zqtA-5jsyA:
undetectable
3zqtA-5jsyA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k3j ACYL-COENZYME A
OXIDASE


(Caenorhabditis
elegans)
PF01756
(ACOX)
PF02770
(Acyl-CoA_dh_M)
PF14749
(Acyl-CoA_ox_N)
4 PRO A 213
GLY A 212
ASN A 210
ASN A 160
None
1.02A 3zqtA-5k3jA:
undetectable
3zqtA-5k3jA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbp GLYCOSYL HYDROLASE,
FAMILY 38


(Enterococcus
faecalis)
PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid)
4 GLY A 827
LEU A 847
ASN A 846
GLU A 888
None
0.99A 3zqtA-5kbpA:
undetectable
3zqtA-5kbpA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpq TRANSGLYCOSYLASE

(Neisseria
meningitidis)
PF01464
(SLT)
PF14718
(SLT_L)
4 GLY A 526
LEU A 516
ASN A 519
GLU A 520
None
0.99A 3zqtA-5mpqA:
undetectable
3zqtA-5mpqA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mwp MINERALOCORTICOID
RECEPTOR


(Homo sapiens)
no annotation 5 PRO A 788
GLY A 789
ASN A 792
ASN A 898
GLU A 902
None
1.07A 3zqtA-5mwpA:
37.2
3zqtA-5mwpA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n28 METHYL-COENZYME M
REDUCTASE SUBUNIT
ALPHA


(Methanotorris
formicicus)
PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N)
4 PRO A 281
GLY A 282
ASN A 476
LEU A 270
None
None
AGM  A 274 ( 3.6A)
AGM  A 274 ( 3.8A)
0.84A 3zqtA-5n28A:
undetectable
3zqtA-5n28A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nz7 CELLODEXTRIN
PHOSPHORYLASE


(Ruminiclostridium
thermocellum)
PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36)
4 GLY A  23
ASN A  19
LEU A  28
ASN A  27
None
0.90A 3zqtA-5nz7A:
undetectable
3zqtA-5nz7A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ols RHAMNOGALACTURONAN
LYASE


(Bacteroides
thetaiotaomicron)
no annotation 4 GLY A 133
LEU A 136
ASN A 135
GLU A  95
None
1.01A 3zqtA-5olsA:
undetectable
3zqtA-5olsA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot4 INTERAPTIN

(Legionella
pneumophila)
no annotation 4 GLY A 293
ASN A 296
ASN A 284
GLU A 287
None
0.96A 3zqtA-5ot4A:
undetectable
3zqtA-5ot4A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u0l N-SUCCINYLGLUTAMATE
5-SEMIALDEHYDE
DEHYDROGENASE


(Marinobacter
hydrocarbonoclasticus)
PF00171
(Aldedh)
4 GLY A 410
ASN A 432
LEU A 437
ASN A 253
None
1.01A 3zqtA-5u0lA:
undetectable
3zqtA-5u0lA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b0n ENVELOPE
GLYCOPROTEIN GP140


(Human
immunodeficiency
virus 1)
no annotation 4 PRO G  43
GLY G  41
LEU G 544
ASN G 543
None
0.99A 3zqtA-6b0nG:
undetectable
3zqtA-6b0nG:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c43 GAMMA-AMINOBUTYRALDE
HYDE DEHYDROGENASE


(Salmonella
enterica)
no annotation 4 PRO A 194
GLY A 195
ASN A 198
ASN A  50
None
1.01A 3zqtA-6c43A:
undetectable
3zqtA-6c43A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33


(Homo sapiens)
no annotation 4 PRO A 228
GLY A 229
ASN B 405
ASN B 104
None
0.91A 3zqtA-6f9nA:
undetectable
3zqtA-6f9nA:
14.00