SIMILAR PATTERNS OF AMINO ACIDS FOR 3ZQ8_A_DVAA6

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0j DNA REPLICATION
PROTEIN

(Adeno-associated
dependoparvovirus
A) 		PF01057
(Parvo_NS1) 		4 ALA A 344
VAL A 418
TRP A 319
TRP A 377
 None
 1.32A 3zq8A-1u0jA:
undetectable
3zq8B-1u0jA:
undetectable		 3zq8A-1u0jA:
4.88
3zq8B-1u0jA:
4.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w98 G1/S-SPECIFIC CYCLIN
E1

(Homo sapiens) 		PF00134
(Cyclin_N)
PF02984
(Cyclin_C) 		4 ALA B 288
VAL B 313
TRP B 315
TRP B 306
 None
 1.31A 3zq8A-1w98B:
undetectable
3zq8B-1w98B:
undetectable		 3zq8A-1w98B:
4.85
3zq8B-1w98B:
4.85