SIMILAR PATTERNS OF AMINO ACIDS FOR 3XIM_A_SORA397

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0c XYLOSE ISOMERASE

(Thermoanaerobacterium
thermosulfurigenes) 		PF01261
(AP_endonuc_2) 		7 HIS A 100
THR A 140
TRP A 187
LYS A 233
GLU A 267
HIS A 270
ASP A 338
 None
None
None
None
CO  A 492 ( 2.5A)
CO  A 492 ( 3.5A)
CO  A 491 ( 3.1A)
 1.35A 3ximA-1a0cA:
38.8		 3ximA-1a0cA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0c XYLOSE ISOMERASE

(Thermoanaerobacterium
thermosulfurigenes) 		PF01261
(AP_endonuc_2) 		6 HIS A 100
THR A 140
VAL A 185
TRP A 187
GLU A 267
ASP A 308
 None
None
None
None
CO  A 492 ( 2.5A)
CO  A 492 ( 2.4A)
 1.34A 3ximA-1a0cA:
38.8		 3ximA-1a0cA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0c XYLOSE ISOMERASE

(Thermoanaerobacterium
thermosulfurigenes) 		PF01261
(AP_endonuc_2) 		11 TRP A  48
HIS A 100
THR A 140
VAL A 185
TRP A 187
LYS A 233
GLU A 267
HIS A 270
ASP A 295
ASP A 306
ASP A 338
 None
None
None
None
None
None
CO  A 492 ( 2.5A)
CO  A 492 ( 3.5A)
CO  A 491 ( 3.1A)
CO  A 492 ( 1.9A)
CO  A 491 ( 3.1A)
 0.47A 3ximA-1a0cA:
38.8		 3ximA-1a0cA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0c XYLOSE ISOMERASE

(Thermoanaerobacterium
thermosulfurigenes) 		PF01261
(AP_endonuc_2) 		5 TRP A 187
LYS A 233
GLU A 267
HIS A 270
ASP A 308
 None
None
CO  A 492 ( 2.5A)
CO  A 492 ( 3.5A)
CO  A 492 ( 2.4A)
 1.48A 3ximA-1a0cA:
38.8		 3ximA-1a0cA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0d XYLOSE ISOMERASE

(Geobacillus
stearothermophilus) 		PF01261
(AP_endonuc_2) 		6 HIS A  98
THR A 138
TRP A 185
GLU A 265
HIS A 268
ASP A 293
 None
None
None
MN  A 492 ( 2.3A)
MN  A 492 (-4.2A)
MN  A 491 ( 3.4A)
 1.29A 3ximA-1a0dA:
38.9		 3ximA-1a0dA:
26.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0d XYLOSE ISOMERASE

(Geobacillus
stearothermophilus) 		PF01261
(AP_endonuc_2) 		5 HIS A  98
THR A 138
VAL A 183
GLU A 265
ASP A 306
 None
None
None
MN  A 492 ( 2.3A)
MN  A 492 ( 2.8A)
 1.35A 3ximA-1a0dA:
38.9		 3ximA-1a0dA:
26.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0d XYLOSE ISOMERASE

(Geobacillus
stearothermophilus) 		PF01261
(AP_endonuc_2) 		11 TRP A  47
HIS A  98
THR A 138
VAL A 183
TRP A 185
LYS A 231
GLU A 265
HIS A 268
ASP A 293
ASP A 304
ASP A 336
 None
None
None
None
None
MN  A 492 ( 4.8A)
MN  A 492 ( 2.3A)
MN  A 492 (-4.2A)
MN  A 491 ( 3.4A)
MN  A 492 ( 3.2A)
MN  A 491 ( 3.1A)
 0.54A 3ximA-1a0dA:
38.9		 3ximA-1a0dA:
26.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0e XYLOSE ISOMERASE

(Thermotoga
neapolitana) 		PF01261
(AP_endonuc_2) 		5 HIS A 100
THR A 140
GLU A 267
ASP A 308
ASP A 295
 None
None
CO  A 492 ( 2.5A)
CO  A 492 (-3.3A)
CO  A 491 ( 3.2A)
 1.42A 3ximA-1a0eA:
40.4		 3ximA-1a0eA:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0e XYLOSE ISOMERASE

(Thermotoga
neapolitana) 		PF01261
(AP_endonuc_2) 		7 HIS A 100
THR A 140
TRP A 187
GLU A 267
HIS A 270
ASP A 338
ASP A 306
 None
None
None
CO  A 492 ( 2.5A)
CO  A 492 ( 3.5A)
CO  A 491 ( 3.0A)
CO  A 492 (-4.3A)
 1.46A 3ximA-1a0eA:
40.4		 3ximA-1a0eA:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0e XYLOSE ISOMERASE

(Thermotoga
neapolitana) 		PF01261
(AP_endonuc_2) 		6 HIS A 100
THR A 140
VAL A 185
GLU A 267
ASP A 295
ASP A 308
 None
None
None
CO  A 492 ( 2.5A)
CO  A 491 ( 3.2A)
CO  A 492 (-3.3A)
 1.18A 3ximA-1a0eA:
40.4		 3ximA-1a0eA:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0e XYLOSE ISOMERASE

(Thermotoga
neapolitana) 		PF01261
(AP_endonuc_2) 		11 TRP A  48
HIS A 100
THR A 140
VAL A 185
TRP A 187
LYS A 233
GLU A 267
HIS A 270
ASP A 295
ASP A 306
ASP A 338
 None
None
None
None
None
CO  A 492 ( 4.4A)
CO  A 492 ( 2.5A)
CO  A 492 ( 3.5A)
CO  A 491 ( 3.2A)
CO  A 492 (-4.3A)
CO  A 491 ( 3.0A)
 0.57A 3ximA-1a0eA:
40.4		 3ximA-1a0eA:
26.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bhw XYLOSE ISOMERASE

(Actinoplanes
missouriensis) 		PF01261
(AP_endonuc_2) 		6 HIS A  54
THR A  90
VAL A 135
GLU A 217
ASP A 245
ASP A 257
 None
 1.21A 3ximA-1bhwA:
62.9		 3ximA-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bhw XYLOSE ISOMERASE

(Actinoplanes
missouriensis) 		PF01261
(AP_endonuc_2) 		5 MET A  88
THR A  90
TRP A 137
GLU A 217
ASP A 292
 None
 1.43A 3ximA-1bhwA:
62.9		 3ximA-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bhw XYLOSE ISOMERASE

(Actinoplanes
missouriensis) 		PF01261
(AP_endonuc_2) 		11 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.23A 3ximA-1bhwA:
62.9		 3ximA-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bxc XYLOSE ISOMERASE

(Thermus
caldophilus) 		PF01261
(AP_endonuc_2) 		7 HIS A  53
MET A  87
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
 None
 1.40A 3ximA-1bxcA:
52.9		 3ximA-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bxc XYLOSE ISOMERASE

(Thermus
caldophilus) 		PF01261
(AP_endonuc_2) 		6 HIS A  53
THR A  89
VAL A 134
GLU A 216
ASP A 244
ASP A 256
 None
 1.17A 3ximA-1bxcA:
52.9		 3ximA-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bxc XYLOSE ISOMERASE

(Thermus
caldophilus) 		PF01261
(AP_endonuc_2) 		12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
 None
 0.43A 3ximA-1bxcA:
52.9		 3ximA-1bxcA:
54.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1de6 L-RHAMNOSE ISOMERASE

(Escherichia
coli) 		PF06134
(RhaA) 		7 TRP A  48
HIS A 103
TRP A 193
LYS A 236
HIS A 270
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 0.75A 3ximA-1de6A:
26.9		 3ximA-1de6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmx HYDROXYQUINOL
1,2-DIOXYGENASE

(Pimelobacter
simplex) 		PF00775
(Dioxygenase_C)
PF04444
(Dioxygenase_N) 		5 MET A  89
THR A 106
VAL A 107
ASP A 249
ASP A 243
 None
 1.25A 3ximA-1tmxA:
undetectable		 3ximA-1tmxA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zo4 METALLO-BETA-LACTAMA
SE FAMILY PROTEIN

(Thermus
thermophilus) 		PF00753
(Lactamase_B) 		5 THR A 137
VAL A 141
HIS A  70
ASP A 190
ASP A  74
 None
None
ZN  A 318 (-3.4A)
ZN  A 319 ( 2.4A)
ZN  A 319 (-2.8A)
 1.41A 3ximA-2zo4A:
undetectable		 3ximA-2zo4A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ktc XYLOSE ISOMERASE

(Pectobacterium
atrosepticum) 		PF01261
(AP_endonuc_2) 		8 TRP A  14
THR A  80
TRP A 126
LYS A 168
HIS A 204
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.58A 3ximA-3ktcA:
35.8		 3ximA-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p14 L-RHAMNOSE ISOMERASE

(Bacillus
halodurans) 		PF06134
(RhaA) 		7 TRP A  38
HIS A  93
TRP A 184
LYS A 227
HIS A 261
ASP A 293
ASP A 325
 None
 0.79A 3ximA-3p14A:
27.4		 3ximA-3p14A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gji L-RHAMNOSE ISOMERASE

(Pseudomonas
stutzeri) 		no annotation 6 TRP A  57
TRP A 179
LYS A 221
HIS A 257
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.47A 3ximA-4gjiA:
33.8		 3ximA-4gjiA:
23.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xia D-XYLOSE ISOMERASE

(Arthrobacter
sp. NRRL B3728) 		PF01261
(AP_endonuc_2) 		5 HIS A  53
THR A  89
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.37A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xia D-XYLOSE ISOMERASE

(Arthrobacter
sp. NRRL B3728) 		PF01261
(AP_endonuc_2) 		5 HIS A  53
THR A  89
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.37A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xia D-XYLOSE ISOMERASE

(Arthrobacter
sp. NRRL B3728) 		PF01261
(AP_endonuc_2) 		6 HIS A  53
THR A  89
VAL A 134
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.15A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xia D-XYLOSE ISOMERASE

(Arthrobacter
sp. NRRL B3728) 		PF01261
(AP_endonuc_2) 		5 THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.35A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xia D-XYLOSE ISOMERASE

(Arthrobacter
sp. NRRL B3728) 		PF01261
(AP_endonuc_2) 		11 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.19A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xia D-XYLOSE ISOMERASE

(Arthrobacter
sp. NRRL B3728) 		PF01261
(AP_endonuc_2) 		9 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
HIS A 219
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
 0.59A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xkm XYLOSE ISOMERASE

(Bacteroides
thetaiotaomicron) 		no annotation 6 HIS A 103
THR A 143
TRP A 190
GLU A 270
HIS A 273
ASP A 298
 None
None
None
MN  A 502 ( 2.5A)
MN  A 502 (-4.2A)
MN  A 501 (-3.2A)
 1.36A 3ximA-4xkmA:
39.1		 3ximA-4xkmA:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xkm XYLOSE ISOMERASE

(Bacteroides
thetaiotaomicron) 		no annotation 6 HIS A 103
THR A 143
VAL A 188
GLU A 270
ASP A 298
ASP A 311
 None
None
None
MN  A 502 ( 2.5A)
MN  A 501 (-3.2A)
MN  A 502 (-2.9A)
 1.31A 3ximA-4xkmA:
39.1		 3ximA-4xkmA:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xkm XYLOSE ISOMERASE

(Bacteroides
thetaiotaomicron) 		no annotation 11 TRP A  51
HIS A 103
THR A 143
VAL A 188
TRP A 190
LYS A 236
GLU A 270
HIS A 273
ASP A 298
ASP A 309
ASP A 341
 None
None
None
None
None
None
MN  A 502 ( 2.5A)
MN  A 502 (-4.2A)
MN  A 501 (-3.2A)
MN  A 502 (-3.3A)
MN  A 501 (-3.1A)
 0.58A 3ximA-4xkmA:
39.1		 3ximA-4xkmA:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iry DESMOCOLLIN-1

(Homo sapiens) 		PF00028
(Cadherin) 		5 VAL A 398
GLU A 402
HIS A 439
ASP A 465
ASP A 348
 None
CA  A 609 ( 2.1A)
None
CA  A 610 ( 3.8A)
CA  A 609 ( 3.1A)
 1.49A 3ximA-5iryA:
undetectable		 3ximA-5iryA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nhb XYLOSE ISOMERASE

(Piromyces sp.
E2) 		no annotation 6 HIS A 102
THR A 142
TRP A 189
GLU A 269
HIS A 272
ASP A 297
 None
None
None
FE2  A 502 ( 2.3A)
FE2  A 502 (-3.6A)
FE2  A 501 (-3.0A)
 1.29A 3ximA-5nhbA:
40.4		 3ximA-5nhbA:
27.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nhb XYLOSE ISOMERASE

(Piromyces sp.
E2) 		no annotation 6 HIS A 102
THR A 142
VAL A 187
GLU A 269
ASP A 297
ASP A 310
 None
None
None
FE2  A 502 ( 2.3A)
FE2  A 501 (-3.0A)
FE2  A 502 ( 3.9A)
 1.26A 3ximA-5nhbA:
40.4		 3ximA-5nhbA:
27.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nhb XYLOSE ISOMERASE

(Piromyces sp.
E2) 		no annotation 11 TRP A  50
HIS A 102
THR A 142
VAL A 187
TRP A 189
LYS A 235
GLU A 269
HIS A 272
ASP A 297
ASP A 308
ASP A 340
 None
None
None
None
None
FE2  A 502 ( 4.1A)
FE2  A 502 ( 2.3A)
FE2  A 502 (-3.6A)
FE2  A 501 (-3.0A)
FE2  A 502 (-3.2A)
FE2  A 501 ( 3.2A)
 0.57A 3ximA-5nhbA:
40.4		 3ximA-5nhbA:
27.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5y4j XYLOSE ISOMERASE

(Streptomyces
rubiginosus) 		PF01261
(AP_endonuc_2) 		7 HIS A  54
MET A  88
THR A  90
TRP A 137
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 (-3.8A)
None
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.31A 3ximA-5y4jA:
57.2		 3ximA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5y4j XYLOSE ISOMERASE

(Streptomyces
rubiginosus) 		PF01261
(AP_endonuc_2) 		6 HIS A  54
THR A  90
TRP A 137
HIS A 220
ASP A 287
ASP A 255
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
XYL  A 402 ( 4.9A)
 1.33A 3ximA-5y4jA:
57.2		 3ximA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5y4j XYLOSE ISOMERASE

(Streptomyces
rubiginosus) 		PF01261
(AP_endonuc_2) 		6 HIS A  54
THR A  90
VAL A 135
GLU A 217
ASP A 245
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
MG  A 401 ( 2.8A)
MG  A 401 ( 3.0A)
None
 1.13A 3ximA-5y4jA:
57.2		 3ximA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5y4j XYLOSE ISOMERASE

(Streptomyces
rubiginosus) 		PF01261
(AP_endonuc_2) 		7 HIS A  54
THR A  90
VAL A 135
TRP A 137
LYS A 183
HIS A 220
ASP A 255
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 (-2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 4.9A)
 0.70A 3ximA-5y4jA:
57.2		 3ximA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5y4j XYLOSE ISOMERASE

(Streptomyces
rubiginosus) 		PF01261
(AP_endonuc_2) 		11 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.21A 3ximA-5y4jA:
57.2		 3ximA-5y4jA:
66.58