SIMILAR PATTERNS OF AMINO ACIDS FOR 3WRK_D_CAMD502_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b9a | PROTEIN(PARVALBUMIN) (Cyprinus carpio) |
PF13499(EF-hand_7) | 4 | PHE A 66GLY A 34THR A 36VAL A 106 | None | 1.06A | 3wrkD-1b9aA:undetectable | 3wrkD-1b9aA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gnx | BETA-GLUCOSIDASE (Streptomycessp.) |
PF00232(Glyco_hydro_1) | 4 | PHE A 184LEU A 276THR A 284VAL A 200 | None | 0.99A | 3wrkD-1gnxA:0.0 | 3wrkD-1gnxA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jiu | DNABETA-GLUCOSYLTRANSFERASE (Escherichiavirus T4) |
PF09198(T4-Gluco-transf) | 4 | PHE A 51LEU A 62THR A 23VAL A 12 | None | 1.03A | 3wrkD-1jiuA:0.0 | 3wrkD-1jiuA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kkc | MANGANESE SUPEROXIDEDISMUTASE (Aspergillusfumigatus) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | PHE A 125LEU A 133GLY A 142VAL A 145 | None | 1.06A | 3wrkD-1kkcA:0.0 | 3wrkD-1kkcA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5j | ACONITATE HYDRATASE2 (Escherichiacoli) |
PF00330(Aconitase)PF06434(Aconitase_2_N)PF11791(Aconitase_B_N) | 4 | PHE A 433LEU A 460GLY A 418VAL A 515 | None | 0.94A | 3wrkD-1l5jA:undetectable | 3wrkD-1l5jA:18.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mc0 | 3',5'-CYCLICNUCLEOTIDEPHOSPHODIESTERASE 2A (Mus musculus) |
PF01590(GAF)PF13185(GAF_2) | 4 | PHE A 363LEU A 242THR A 249VAL A 358 | None | 0.98A | 3wrkD-1mc0A:0.0 | 3wrkD-1mc0A:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1og3 | T-CELLECTO-ADP-RIBOSYLTRANSFERASE 2 (Rattusnorvegicus) |
PF01129(ART) | 4 | LEU A 113GLY A 175THR A 172VAL A 124 | None | 0.93A | 3wrkD-1og3A:undetectable | 3wrkD-1og3A:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qd1 | FORMIMINOTRANSFERASE-CYCLODEAMINASE (Sus scrofa) |
PF02971(FTCD)PF07837(FTCD_N) | 4 | LEU A 269GLY A 271THR A 50VAL A 8 | None | 1.06A | 3wrkD-1qd1A:undetectable | 3wrkD-1qd1A:23.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qfh | PROTEIN (GELATIONFACTOR) (Dictyosteliumdiscoideum) |
PF00630(Filamin) | 4 | PHE A 850LEU A 811GLY A 813VAL A 847 | None | 0.93A | 3wrkD-1qfhA:undetectable | 3wrkD-1qfhA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s78 | PERTUZUMAB FAB HEAVYCHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | PHE D 122GLY D 118THR D 205VAL D 207 | None | 1.00A | 3wrkD-1s78D:undetectable | 3wrkD-1s78D:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tfd | TRANSFERRIN (Oryctolaguscuniculus) |
PF00405(Transferrin) | 4 | PHE A 186LEU A 66GLY A 123VAL A 159 | None | 0.90A | 3wrkD-1tfdA:undetectable | 3wrkD-1tfdA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uuf | ZINC-TYPE ALCOHOLDEHYDROGENASE-LIKEPROTEIN YAHK (Escherichiacoli) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 193GLY A 190THR A 244VAL A 267 | None | 0.97A | 3wrkD-1uufA:undetectable | 3wrkD-1uufA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uwy | CARBOXYPEPTIDASE M (Homo sapiens) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 4 | LEU A 244GLY A 238THR A 236VAL A 178 | None | 1.00A | 3wrkD-1uwyA:undetectable | 3wrkD-1uwyA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uzd | RIBULOSEBISPHOSPHATECARBOXYLASE SMALLCHAIN 1, RIBULOSEBISPHOSPHATECARBOXYLASE SMALLCHAIN 2 (Chlamydomonasreinhardtii;Spinaciaoleracea) |
PF00101(RuBisCO_small) | 4 | PHE C 115LEU C 84THR C 91VAL C 99 | None | 1.03A | 3wrkD-1uzdC:undetectable | 3wrkD-1uzdC:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yir | NICOTINATEPHOSPHORIBOSYLTRANSFERASE 2 (Pseudomonasaeruginosa) |
PF04095(NAPRTase) | 4 | PHE A 204GLY A 345THR A 349VAL A 192 | NoneSO4 A2002 (-3.4A)NoneNone | 1.00A | 3wrkD-1yirA:undetectable | 3wrkD-1yirA:25.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zlp | PETAL DEATH PROTEIN (Dianthuscaryophyllus) |
PF13714(PEP_mutase) | 4 | LEU A 135GLY A 111THR A 85VAL A 88 | None | 1.08A | 3wrkD-1zlpA:undetectable | 3wrkD-1zlpA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zx5 | MANNOSEPHOSPHATEISOMERASE, PUTATIVE (Archaeoglobusfulgidus) |
PF01238(PMI_typeI) | 4 | PHE A 8GLY A 262THR A 280VAL A 276 | None | 1.02A | 3wrkD-1zx5A:undetectable | 3wrkD-1zx5A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dno | TRINUCLEOTIDE REPEATCONTAINING 4 VARIANT (Homo sapiens) |
PF00076(RRM_1) | 4 | PHE A 91LEU A 137GLY A 79VAL A 102 | None | 1.08A | 3wrkD-2dnoA:undetectable | 3wrkD-2dnoA:13.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ftw | DIHYDROPYRIMIDINEAMIDOHYDROLASE (Dictyosteliumdiscoideum) |
PF01979(Amidohydro_1) | 4 | PHE A 373GLY A 92THR A 439VAL A 403 | None | 1.03A | 3wrkD-2ftwA:undetectable | 3wrkD-2ftwA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g6b | RAS-RELATED PROTEINRAB-26 (Homo sapiens) |
PF00071(Ras) | 4 | PHE A 218LEU A 143GLY A 75VAL A 81 | NoneNoneGNP A 302 (-3.3A)None | 1.02A | 3wrkD-2g6bA:undetectable | 3wrkD-2g6bA:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gm3 | UNKNOWN PROTEIN (Arabidopsisthaliana) |
PF00582(Usp) | 4 | PHE A 31GLY A 100THR A 43VAL A 39 | None | 1.09A | 3wrkD-2gm3A:undetectable | 3wrkD-2gm3A:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inp | PHENOL HYDROXYLASECOMPONENT PHNPHENOL HYDROXYLASECOMPONENT PHL (Pseudomonasstutzeri;Pseudomonasstutzeri) |
PF02332(Phenol_Hydrox)PF04945(YHS)PF02332(Phenol_Hydrox) | 4 | PHE A 34LEU C 131GLY C 132THR C 205 | None | 1.07A | 3wrkD-2inpA:undetectable | 3wrkD-2inpA:20.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 5 | PHE A 87LEU A 244GLY A 248THR A 252VAL A 396 | CAM A 502 (-4.6A)HEM A 501 (-4.5A)HEM A 501 (-3.9A)HEM A 501 (-3.4A)None | 0.79A | 3wrkD-2m56A:56.6 | 3wrkD-2m56A:99.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nsm | CARBOXYPEPTIDASE NCATALYTIC CHAIN (Homo sapiens) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 4 | LEU A 268GLY A 262THR A 260VAL A 201 | SO4 A1776 (-4.9A)NoneNoneNone | 1.04A | 3wrkD-2nsmA:undetectable | 3wrkD-2nsmA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nym | SERINE/THREONINE-PROTEIN PHOSPHATASE 2ACATALYTIC SUBUNITALPHA ISOFORM (Homo sapiens) |
PF00149(Metallophos) | 4 | PHE C 228LEU C 198GLY C 168VAL C 256 | None | 1.06A | 3wrkD-2nymC:undetectable | 3wrkD-2nymC:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oaj | PROTEIN SNI1 (Saccharomycescerevisiae) |
PF08596(Lgl_C) | 4 | PHE A 844LEU A 804GLY A 781THR A 738 | None | 0.95A | 3wrkD-2oajA:undetectable | 3wrkD-2oajA:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vr2 | DIHYDROPYRIMIDINASE (Homo sapiens) |
PF01979(Amidohydro_1) | 4 | PHE A 374GLY A 93THR A 440VAL A 404 | None | 0.99A | 3wrkD-2vr2A:undetectable | 3wrkD-2vr2A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x3e | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Pseudomonasaeruginosa) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | PHE A 114LEU A 176GLY A 122VAL A 76 | None | 0.97A | 3wrkD-2x3eA:undetectable | 3wrkD-2x3eA:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | LEU A 226GLY A 230THR A 234VAL A 277 | HEM A1400 (-4.4A)PG4 A1399 ( 3.2A)HEM A1400 (-3.7A)HEM A1400 (-4.5A) | 0.90A | 3wrkD-2xkrA:43.6 | 3wrkD-2xkrA:28.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | LEU A 226GLY A 230THR A 234VAL A 381 | HEM A1400 (-4.4A)PG4 A1399 ( 3.2A)HEM A1400 (-3.7A)None | 0.42A | 3wrkD-2xkrA:43.6 | 3wrkD-2xkrA:28.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aje | PUTATIVEUNCHARACTERIZEDPROTEIN ST1526 (Sulfurisphaeratokodaii) |
PF01300(Sua5_yciO_yrdC)PF03481(SUA5) | 4 | PHE A 302LEU A 245GLY A 317VAL A 294 | None | 0.90A | 3wrkD-3ajeA:undetectable | 3wrkD-3ajeA:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bol | 5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINEMETHYLTRANSFERASE (Thermotogamaritima) |
PF00809(Pterin_bind)PF02574(S-methyl_trans) | 4 | PHE A 283LEU A 249GLY A 210VAL A 231 | None | 0.98A | 3wrkD-3bolA:undetectable | 3wrkD-3bolA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c2g | SYS-1 PROTEIN (Caenorhabditiselegans) |
no annotation | 4 | PHE A 294LEU A 261THR A 268VAL A 280 | None | 1.02A | 3wrkD-3c2gA:undetectable | 3wrkD-3c2gA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3epm | THIAMINEBIOSYNTHESIS PROTEINTHIC (Caulobactervibrioides) |
PF01964(ThiC_Rad_SAM)PF13667(ThiC-associated) | 4 | LEU A 393GLY A 397THR A 400VAL A 410 | None | 1.06A | 3wrkD-3epmA:undetectable | 3wrkD-3epmA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gaz | ALCOHOLDEHYDROGENASESUPERFAMILY PROTEIN (Novosphingobiumaromaticivorans) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | PHE A 85GLY A 93THR A 95VAL A 111 | None | 1.01A | 3wrkD-3gazA:undetectable | 3wrkD-3gazA:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gv0 | TRANSCRIPTIONALREGULATOR, LACIFAMILY (Agrobacteriumfabrum) |
PF13377(Peripla_BP_3) | 4 | LEU A 120GLY A 123THR A 66VAL A 68 | None | 1.08A | 3wrkD-3gv0A:undetectable | 3wrkD-3gv0A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ibj | CGMP-DEPENDENT3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I)PF01590(GAF)PF13185(GAF_2) | 4 | PHE A 370LEU A 250THR A 257VAL A 365 | None | 0.94A | 3wrkD-3ibjA:undetectable | 3wrkD-3ibjA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3khy | PROPIONATE KINASE (Francisellatularensis) |
PF00871(Acetate_kinase) | 4 | LEU A 201GLY A 321THR A 370VAL A 181 | None | 0.93A | 3wrkD-3khyA:undetectable | 3wrkD-3khyA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mc2 | INHIBITOR OFCARBONIC ANHYDRASE (Mus musculus) |
PF00405(Transferrin) | 4 | PHE A 186LEU A 66GLY A 123VAL A 154 | None | 0.78A | 3wrkD-3mc2A:undetectable | 3wrkD-3mc2A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mn8 | LP15968P (Drosophilamelanogaster) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 4 | LEU A 285GLY A 279THR A 277VAL A 222 | GEM A 601 (-4.0A)GEM A 601 (-3.3A)NoneNone | 1.04A | 3wrkD-3mn8A:undetectable | 3wrkD-3mn8A:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ng9 | CAPSID PROTEIN (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | PHE A 292LEU A 687GLY A 306VAL A 612 | None | 1.04A | 3wrkD-3ng9A:undetectable | 3wrkD-3ng9A:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0k | ALDO/KETO REDUCTASE (Brucellaabortus) |
PF00248(Aldo_ket_red) | 4 | PHE A 90LEU A 178GLY A 156VAL A 152 | None | 0.90A | 3wrkD-3o0kA:undetectable | 3wrkD-3o0kA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ra2 | CAPSID PROTEIN (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | PHE A 294LEU A 689GLY A 308VAL A 614 | None | 1.06A | 3wrkD-3ra2A:undetectable | 3wrkD-3ra2A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s6p | CAPSID PROTEIN (Helicoverpaarmigera stuntvirus) |
PF03566(Peptidase_A21) | 4 | PHE A 514LEU A 459GLY A 266THR A 439 | None | 1.04A | 3wrkD-3s6pA:undetectable | 3wrkD-3s6pA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3shm | CAPSID PROTEIN VP1 (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | PHE A 292LEU A 687GLY A 306VAL A 612 | None | 1.08A | 3wrkD-3shmA:undetectable | 3wrkD-3shmA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3slc | ACETATE KINASE (Salmonellaenterica) |
PF00871(Acetate_kinase) | 4 | LEU A 211GLY A 332THR A 385VAL A 189 | None | 1.06A | 3wrkD-3slcA:undetectable | 3wrkD-3slcA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ta6 | TRIOSEPHOSPHATEISOMERASE (Mycobacteriumtuberculosis) |
PF00121(TIM) | 4 | PHE A 248LEU A 6GLY A 235VAL A 219 | None | 1.00A | 3wrkD-3ta6A:undetectable | 3wrkD-3ta6A:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3upg | OUTER MEMBRANEPROTEIN C (Salmonellaenterica) |
PF00267(Porin_1) | 4 | LEU A 107GLY A 112THR A 114VAL A 287 | None | 1.00A | 3wrkD-3upgA:undetectable | 3wrkD-3upgA:19.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3zby | P450 HEME-THIOLATEPROTEIN (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 4 | LEU A 229GLY A 233THR A 237VAL A 280 | HEM A1402 ( 4.6A)EDO A1406 ( 3.4A)HEM A1402 (-3.7A)HEM A1402 (-4.4A) | 0.89A | 3wrkD-3zbyA:43.2 | 3wrkD-3zbyA:31.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3zby | P450 HEME-THIOLATEPROTEIN (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 4 | LEU A 229GLY A 233THR A 237VAL A 383 | HEM A1402 ( 4.6A)EDO A1406 ( 3.4A)HEM A1402 (-3.7A)None | 0.41A | 3wrkD-3zbyA:43.2 | 3wrkD-3zbyA:31.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b0n | POLYKETIDE SYNTHASEIII (Ectocarpussiliculosus) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | PHE A 165LEU A 284GLY A 193VAL A 160 | MLA A1415 (-4.3A)ACD A1416 (-4.3A)ACD A1416 ( 4.3A)None | 1.03A | 3wrkD-4b0nA:undetectable | 3wrkD-4b0nA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b90 | DIHYDROPYRIMIDINASE-RELATED PROTEIN 5 (Homo sapiens) |
PF01979(Amidohydro_1) | 4 | PHE A 373GLY A 92THR A 439VAL A 403 | None | 1.05A | 3wrkD-4b90A:undetectable | 3wrkD-4b90A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b92 | DIHYDROPYRIMIDINASE-RELATED PROTEIN 5 (Homo sapiens) |
PF01979(Amidohydro_1) | 4 | PHE A 373GLY A 92THR A 439VAL A 403 | None | 1.01A | 3wrkD-4b92A:undetectable | 3wrkD-4b92A:22.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c9m | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 4 | LEU A 252GLY A 256THR A 260VAL A 404 | HEM A1418 (-4.0A)HEM A1418 (-3.8A)HEM A1418 (-3.6A)GOL A1419 (-3.5A) | 0.62A | 3wrkD-4c9mA:50.7 | 3wrkD-4c9mA:45.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dxy | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 5 | PHE A 87LEU A 250GLY A 254THR A 258VAL A 301 | NoneHEM A 501 (-4.3A)PEG A 502 (-3.8A)HEM A 501 (-3.7A)PEG A 502 ( 4.5A) | 1.47A | 3wrkD-4dxyA:54.0 | 3wrkD-4dxyA:46.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dxy | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 5 | PHE A 87LEU A 250GLY A 254THR A 258VAL A 402 | NoneHEM A 501 (-4.3A)PEG A 502 (-3.8A)HEM A 501 (-3.7A)None | 0.54A | 3wrkD-4dxyA:54.0 | 3wrkD-4dxyA:46.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fwm | PROPIONATE KINASE (Salmonellaenterica) |
PF00871(Acetate_kinase) | 4 | LEU A 204GLY A 325THR A 379VAL A 182 | NoneATP A 405 ( 4.5A)NoneNone | 0.99A | 3wrkD-4fwmA:undetectable | 3wrkD-4fwmA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fzi | PROSTAGLANDIN FSYNTHASE (Trypanosomacruzi) |
PF00248(Aldo_ket_red) | 4 | PHE A 277GLY A 85THR A 89VAL A 79 | None | 1.00A | 3wrkD-4fziA:undetectable | 3wrkD-4fziA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g78 | HISTIDINEPHOSPHOTRANSFERPROTEIN (Medicagotruncatula) |
PF01627(Hpt) | 4 | PHE A 132LEU A 21GLY A 87VAL A 43 | None | 1.07A | 3wrkD-4g78A:undetectable | 3wrkD-4g78A:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gz7 | DIHYDROPYRIMIDINASE (Tetraodonnigroviridis) |
PF01979(Amidohydro_1) | 4 | PHE A 370GLY A 89THR A 436VAL A 400 | None | 1.01A | 3wrkD-4gz7A:undetectable | 3wrkD-4gz7A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hhr | ALPHA-DIOXYGENASE (Arabidopsisthaliana) |
PF03098(An_peroxidase) | 4 | PHE A 549LEU A 59GLY A 335VAL A 324 | None | 1.00A | 3wrkD-4hhrA:undetectable | 3wrkD-4hhrA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hyq | PHOSPHOLIPASE A1 (Streptomycesalbidoflavus) |
PF13472(Lipase_GDSL_2) | 4 | LEU A 171GLY A 81THR A 58VAL A 124 | None | 1.04A | 3wrkD-4hyqA:undetectable | 3wrkD-4hyqA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ijn | ACETATE KINASE (Mycolicibacteriumsmegmatis) |
PF00871(Acetate_kinase) | 4 | PHE A 132LEU A 180GLY A 201VAL A 205 | NoneNoneEDO A 403 (-3.6A)None | 0.89A | 3wrkD-4ijnA:undetectable | 3wrkD-4ijnA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kq9 | RIBOSE ABCTRANSPORTER,SUBSTRATE BINDINGPROTEIN (Conexibacterwoesei) |
PF13407(Peripla_BP_4) | 4 | LEU A 244GLY A 245THR A 222VAL A 177 | None | 1.04A | 3wrkD-4kq9A:undetectable | 3wrkD-4kq9A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1m | E3 UBIQUITIN-PROTEINLIGASE HERC2 (Homo sapiens) |
PF00415(RCC1) | 4 | PHE A 463LEU A 482GLY A 447VAL A 453 | None | 1.08A | 3wrkD-4l1mA:undetectable | 3wrkD-4l1mA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mfi | SN-GLYCEROL-3-PHOSPHATE ABC TRANSPORTERSUBSTRATE-BINDINGPROTEIN USPB (Mycobacteriumtuberculosis) |
PF13416(SBP_bac_8) | 4 | PHE A 339LEU A 99GLY A 308VAL A 348 | None | 0.88A | 3wrkD-4mfiA:0.8 | 3wrkD-4mfiA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nte | DEPH (Chromobacteriumviolaceum) |
PF07992(Pyr_redox_2) | 4 | PHE A 111GLY A 238THR A 260VAL A 263 | None | 1.09A | 3wrkD-4nteA:undetectable | 3wrkD-4nteA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nvt | TRIOSEPHOSPHATEISOMERASE (Brucellamelitensis) |
PF00121(TIM) | 4 | PHE A 244LEU A 8GLY A 231VAL A 215 | None | 0.84A | 3wrkD-4nvtA:undetectable | 3wrkD-4nvtA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q05 | ESTERASE E25 (unculturedbacterium) |
PF07859(Abhydrolase_3) | 4 | LEU A 210GLY A 183THR A 116VAL A 164 | None | 0.98A | 3wrkD-4q05A:undetectable | 3wrkD-4q05A:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rjk | ACETOLACTATESYNTHASE (Bacillussubtilis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | PHE A 168LEU A 126GLY A 86VAL A 83 | None | 1.08A | 3wrkD-4rjkA:undetectable | 3wrkD-4rjkA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tqt | D-HYDANTOINASE (Brucella suis) |
PF01979(Amidohydro_1) | 4 | PHE A 365GLY A 87THR A 431VAL A 395 | None | 1.08A | 3wrkD-4tqtA:undetectable | 3wrkD-4tqtA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tx8 | PROBABLE CHITINASE A (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18) | 4 | PHE A 386LEU A 347GLY A 370VAL A 86 | None | 1.08A | 3wrkD-4tx8A:undetectable | 3wrkD-4tx8A:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ue0 | FIBER (Bovineatadenovirus D) |
no annotation | 4 | PHE A 467LEU A 451GLY A 437VAL A 426 | None | 1.07A | 3wrkD-4ue0A:undetectable | 3wrkD-4ue0A:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y9a | TRIOSEPHOSPHATEISOMERASE (Streptomycescoelicolor) |
PF00121(TIM) | 4 | PHE A 252LEU A 10GLY A 239VAL A 223 | None | 1.01A | 3wrkD-4y9aA:undetectable | 3wrkD-4y9aA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yet | SUPEROXIDE DISMUTASE (Babesia bovis) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | PHE A 107LEU A 115GLY A 124VAL A 127 | None | 1.02A | 3wrkD-4yetA:undetectable | 3wrkD-4yetA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ypg | INTERFERON ALPHA-2 (Homo sapiens) |
PF00143(Interferon) | 4 | PHE C 38GLY C 44THR C 52VAL C 55 | None | 1.03A | 3wrkD-4ypgC:undetectable | 3wrkD-4ypgC:16.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5axh | DEXTRANASE (Thermoanaerobacterpseudethanolicus) |
PF13199(Glyco_hydro_66) | 4 | PHE A 433LEU A 442GLY A 153VAL A 404 | None | 0.97A | 3wrkD-5axhA:undetectable | 3wrkD-5axhA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5by3 | BTGH115A (Bacteroidesthetaiotaomicron) |
PF15979(Glyco_hydro_115) | 4 | LEU A 78GLY A 71THR A 116VAL A 40 | None | 1.00A | 3wrkD-5by3A:undetectable | 3wrkD-5by3A:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d39 | SIGNAL TRANSDUCERAND ACTIVATOR OFTRANSCRIPTION 6 (Homo sapiens) |
PF00017(SH2)PF01017(STAT_alpha)PF02864(STAT_bind) | 4 | PHE A 518GLY A 468THR A 465VAL A 463 | None | 1.04A | 3wrkD-5d39A:undetectable | 3wrkD-5d39A:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fl7 | ATP SYNTHASE SUBUNITALPHA (Yarrowialipolytica) |
PF00006(ATP-synt_ab)PF00306(ATP-synt_ab_C)PF02874(ATP-synt_ab_N) | 4 | PHE A 294LEU A 347GLY A 280VAL A 258 | None | 0.94A | 3wrkD-5fl7A:undetectable | 3wrkD-5fl7A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fyj | GP41 ENV ECTODOMAINGP120 ENV ECTODOMAIN (Humanimmunodeficiencyvirus 1;Humanimmunodeficiencyvirus 1) |
PF00517(GP41)PF00516(GP120) | 4 | LEU G 86GLY B 524THR B 536VAL B 539 | None | 0.75A | 3wrkD-5fyjG:undetectable | 3wrkD-5fyjG:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j60 | THIOREDOXINREDUCTASE (Gloeobacterviolaceus) |
PF07992(Pyr_redox_2) | 4 | PHE A 247GLY A 275THR A 268VAL A 252 | FAD A 401 ( 4.3A)NoneNoneNone | 0.71A | 3wrkD-5j60A:undetectable | 3wrkD-5j60A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j72 | PUTATIVEN-ACETYLMURAMOYL-L-ALANINEAMIDASE,AUTOLYSINCWP6 (Clostridioidesdifficile) |
PF01520(Amidase_3)PF04122(CW_binding_2) | 4 | LEU A 329GLY A 324THR A 358VAL A 362 | None | 1.05A | 3wrkD-5j72A:undetectable | 3wrkD-5j72A:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5knn | ALANINE--TRNALIGASE, CYTOPLASMIC (Homo sapiens) |
PF01411(tRNA-synt_2c) | 4 | PHE A 126LEU A 101GLY A 243VAL A 250 | NoneNoneA5A A 500 (-3.4A)None | 1.08A | 3wrkD-5knnA:undetectable | 3wrkD-5knnA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mu5 | UNCHARACTERIZEDPROTEIN (Magnetospirillummagneticum) |
no annotation | 4 | PHE A 629LEU A 579GLY A 596VAL A 94 | None | 1.00A | 3wrkD-5mu5A:undetectable | 3wrkD-5mu5A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nzg | UDP-GLUCOSEPYROPHOSPHORYLASE (Leishmaniamajor) |
no annotation | 4 | PHE A 242LEU A 330GLY A 192VAL A 217 | None | 0.90A | 3wrkD-5nzgA:undetectable | 3wrkD-5nzgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tir | SUPEROXIDE DISMUTASE (Trichodermareesei) |
no annotation | 4 | PHE A 115LEU A 123GLY A 132VAL A 135 | None | 1.03A | 3wrkD-5tirA:1.3 | 3wrkD-5tirA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u1d | ANTIGEN PEPTIDETRANSPORTER 1ANTIGEN PEPTIDETRANSPORTER 2 (Homo sapiens;Homo sapiens) |
PF00005(ABC_tran)PF00664(ABC_membrane)PF00005(ABC_tran)PF00664(ABC_membrane) | 4 | PHE B 189LEU A 427GLY A 431THR A 435 | None | 1.07A | 3wrkD-5u1dB:1.7 | 3wrkD-5u1dB:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u84 | ACID CERAMIDASE (Balaenopteraacutorostrata) |
no annotation | 4 | PHE A 381GLY A 203THR A 186VAL A 47 | None | 1.03A | 3wrkD-5u84A:undetectable | 3wrkD-5u84A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9p | GLUCONATE5-DEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 4 | PHE A 194GLY A 252THR A 254VAL A 149 | None | 1.01A | 3wrkD-5u9pA:undetectable | 3wrkD-5u9pA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wdu | ENVELOPEGLYCOPROTEIN GP160ENVELOPEGLYCOPROTEIN GP160 (Humanimmunodeficiencyvirus 1;Humanimmunodeficiencyvirus 1) |
no annotationno annotation | 4 | LEU G 86GLY A 524THR A 536VAL A 539 | None | 1.07A | 3wrkD-5wduG:undetectable | 3wrkD-5wduG:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwq | FUNGAL CHITINASEFROM RHIZOMUCORMIEHEI (NATIVEPROTEIN) (Rhizomucormiehei) |
no annotation | 4 | LEU A 305GLY A 286THR A 284VAL A 258 | None | 1.04A | 3wrkD-5xwqA:undetectable | 3wrkD-5xwqA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yba | PEPTIDYL-PROLYLCIS-TRANS ISOMERASE (Trichomonasvaginalis) |
no annotation | 4 | PHE A 23GLY A 73THR A 59VAL A 166 | None | 1.05A | 3wrkD-5ybaA:undetectable | 3wrkD-5ybaA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zh6 | - (-) |
no annotation | 4 | PHE A 64GLY A 32THR A 34VAL A 104 | None | 1.06A | 3wrkD-5zh6A:undetectable | 3wrkD-5zh6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ax8 | METHIONINE-TRNALIGASE (Mycobacteriumtuberculosis) |
no annotation | 4 | LEU A 475GLY A 479THR A 498VAL A 374 | None | 1.08A | 3wrkD-6ax8A:undetectable | 3wrkD-6ax8A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b74 | COAGULATION FACTORXII (Homo sapiens) |
no annotation | 4 | LEU B 20GLY B 19THR B 188VAL B 160 | None | 0.91A | 3wrkD-6b74B:undetectable | 3wrkD-6b74B:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bme | TRUNCATED HEMOGLOBIN4 (Chlamydomonasreinhardtii) |
no annotation | 4 | PHE A 121LEU A 34GLY A 86VAL A 141 | None | 1.01A | 3wrkD-6bmeA:undetectable | 3wrkD-6bmeA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MBH13 NADHDEHYDROGENASESUBUNIT (Pyrococcusfuriosus) |
no annotation | 4 | LEU M 137GLY M 133THR M 218VAL M 118 | None | 1.09A | 3wrkD-6cfwM:1.2 | 3wrkD-6cfwM:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6emk | SERINE/THREONINE-PROTEIN KINASE TOR2 (Saccharomycescerevisiae) |
no annotation | 4 | PHE A2141LEU A2273GLY A2270VAL A2292 | None | 0.99A | 3wrkD-6emkA:undetectable | 3wrkD-6emkA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g1i | - (-) |
no annotation | 4 | PHE A 186LEU A 291GLY A 290VAL A 183 | None | 0.99A | 3wrkD-6g1iA:undetectable | 3wrkD-6g1iA:undetectable |