SIMILAR PATTERNS OF AMINO ACIDS FOR 3WRK_D_CAMD502_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b9a PROTEIN
(PARVALBUMIN)


(Cyprinus carpio)
PF13499
(EF-hand_7)
4 PHE A  66
GLY A  34
THR A  36
VAL A 106
None
1.06A 3wrkD-1b9aA:
undetectable
3wrkD-1b9aA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gnx BETA-GLUCOSIDASE

(Streptomyces
sp.)
PF00232
(Glyco_hydro_1)
4 PHE A 184
LEU A 276
THR A 284
VAL A 200
None
0.99A 3wrkD-1gnxA:
0.0
3wrkD-1gnxA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE


(Escherichia
virus T4)
PF09198
(T4-Gluco-transf)
4 PHE A  51
LEU A  62
THR A  23
VAL A  12
None
1.03A 3wrkD-1jiuA:
0.0
3wrkD-1jiuA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kkc MANGANESE SUPEROXIDE
DISMUTASE


(Aspergillus
fumigatus)
PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C)
4 PHE A 125
LEU A 133
GLY A 142
VAL A 145
None
1.06A 3wrkD-1kkcA:
0.0
3wrkD-1kkcA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5j ACONITATE HYDRATASE
2


(Escherichia
coli)
PF00330
(Aconitase)
PF06434
(Aconitase_2_N)
PF11791
(Aconitase_B_N)
4 PHE A 433
LEU A 460
GLY A 418
VAL A 515
None
0.94A 3wrkD-1l5jA:
undetectable
3wrkD-1l5jA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mc0 3',5'-CYCLIC
NUCLEOTIDE
PHOSPHODIESTERASE 2A


(Mus musculus)
PF01590
(GAF)
PF13185
(GAF_2)
4 PHE A 363
LEU A 242
THR A 249
VAL A 358
None
0.98A 3wrkD-1mc0A:
0.0
3wrkD-1mc0A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1og3 T-CELL
ECTO-ADP-RIBOSYLTRAN
SFERASE 2


(Rattus
norvegicus)
PF01129
(ART)
4 LEU A 113
GLY A 175
THR A 172
VAL A 124
None
0.93A 3wrkD-1og3A:
undetectable
3wrkD-1og3A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE


(Sus scrofa)
PF02971
(FTCD)
PF07837
(FTCD_N)
4 LEU A 269
GLY A 271
THR A  50
VAL A   8
None
1.06A 3wrkD-1qd1A:
undetectable
3wrkD-1qd1A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfh PROTEIN (GELATION
FACTOR)


(Dictyostelium
discoideum)
PF00630
(Filamin)
4 PHE A 850
LEU A 811
GLY A 813
VAL A 847
None
0.93A 3wrkD-1qfhA:
undetectable
3wrkD-1qfhA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s78 PERTUZUMAB FAB HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 PHE D 122
GLY D 118
THR D 205
VAL D 207
None
1.00A 3wrkD-1s78D:
undetectable
3wrkD-1s78D:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tfd TRANSFERRIN

(Oryctolagus
cuniculus)
PF00405
(Transferrin)
4 PHE A 186
LEU A  66
GLY A 123
VAL A 159
None
0.90A 3wrkD-1tfdA:
undetectable
3wrkD-1tfdA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uuf ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN YAHK


(Escherichia
coli)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 LEU A 193
GLY A 190
THR A 244
VAL A 267
None
0.97A 3wrkD-1uufA:
undetectable
3wrkD-1uufA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uwy CARBOXYPEPTIDASE M

(Homo sapiens)
PF00246
(Peptidase_M14)
PF13620
(CarboxypepD_reg)
4 LEU A 244
GLY A 238
THR A 236
VAL A 178
None
1.00A 3wrkD-1uwyA:
undetectable
3wrkD-1uwyA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uzd RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 1, RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 2


(Chlamydomonas
reinhardtii;
Spinacia
oleracea)
PF00101
(RuBisCO_small)
4 PHE C 115
LEU C  84
THR C  91
VAL C  99
None
1.03A 3wrkD-1uzdC:
undetectable
3wrkD-1uzdC:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yir NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE 2


(Pseudomonas
aeruginosa)
PF04095
(NAPRTase)
4 PHE A 204
GLY A 345
THR A 349
VAL A 192
None
SO4  A2002 (-3.4A)
None
None
1.00A 3wrkD-1yirA:
undetectable
3wrkD-1yirA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zlp PETAL DEATH PROTEIN

(Dianthus
caryophyllus)
PF13714
(PEP_mutase)
4 LEU A 135
GLY A 111
THR A  85
VAL A  88
None
1.08A 3wrkD-1zlpA:
undetectable
3wrkD-1zlpA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE


(Archaeoglobus
fulgidus)
PF01238
(PMI_typeI)
4 PHE A   8
GLY A 262
THR A 280
VAL A 276
None
1.02A 3wrkD-1zx5A:
undetectable
3wrkD-1zx5A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dno TRINUCLEOTIDE REPEAT
CONTAINING 4 VARIANT


(Homo sapiens)
PF00076
(RRM_1)
4 PHE A  91
LEU A 137
GLY A  79
VAL A 102
None
1.08A 3wrkD-2dnoA:
undetectable
3wrkD-2dnoA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ftw DIHYDROPYRIMIDINE
AMIDOHYDROLASE


(Dictyostelium
discoideum)
PF01979
(Amidohydro_1)
4 PHE A 373
GLY A  92
THR A 439
VAL A 403
None
1.03A 3wrkD-2ftwA:
undetectable
3wrkD-2ftwA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g6b RAS-RELATED PROTEIN
RAB-26


(Homo sapiens)
PF00071
(Ras)
4 PHE A 218
LEU A 143
GLY A  75
VAL A  81
None
None
GNP  A 302 (-3.3A)
None
1.02A 3wrkD-2g6bA:
undetectable
3wrkD-2g6bA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gm3 UNKNOWN PROTEIN

(Arabidopsis
thaliana)
PF00582
(Usp)
4 PHE A  31
GLY A 100
THR A  43
VAL A  39
None
1.09A 3wrkD-2gm3A:
undetectable
3wrkD-2gm3A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inp PHENOL HYDROXYLASE
COMPONENT PHN
PHENOL HYDROXYLASE
COMPONENT PHL


(Pseudomonas
stutzeri;
Pseudomonas
stutzeri)
PF02332
(Phenol_Hydrox)
PF04945
(YHS)
PF02332
(Phenol_Hydrox)
4 PHE A  34
LEU C 131
GLY C 132
THR C 205
None
1.07A 3wrkD-2inpA:
undetectable
3wrkD-2inpA:
20.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE


(Pseudomonas
putida)
PF00067
(p450)
5 PHE A  87
LEU A 244
GLY A 248
THR A 252
VAL A 396
CAM  A 502 (-4.6A)
HEM  A 501 (-4.5A)
HEM  A 501 (-3.9A)
HEM  A 501 (-3.4A)
None
0.79A 3wrkD-2m56A:
56.6
3wrkD-2m56A:
99.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nsm CARBOXYPEPTIDASE N
CATALYTIC CHAIN


(Homo sapiens)
PF00246
(Peptidase_M14)
PF13620
(CarboxypepD_reg)
4 LEU A 268
GLY A 262
THR A 260
VAL A 201
SO4  A1776 (-4.9A)
None
None
None
1.04A 3wrkD-2nsmA:
undetectable
3wrkD-2nsmA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nym SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
CATALYTIC SUBUNIT
ALPHA ISOFORM


(Homo sapiens)
PF00149
(Metallophos)
4 PHE C 228
LEU C 198
GLY C 168
VAL C 256
None
1.06A 3wrkD-2nymC:
undetectable
3wrkD-2nymC:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oaj PROTEIN SNI1

(Saccharomyces
cerevisiae)
PF08596
(Lgl_C)
4 PHE A 844
LEU A 804
GLY A 781
THR A 738
None
0.95A 3wrkD-2oajA:
undetectable
3wrkD-2oajA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vr2 DIHYDROPYRIMIDINASE

(Homo sapiens)
PF01979
(Amidohydro_1)
4 PHE A 374
GLY A  93
THR A 440
VAL A 404
None
0.99A 3wrkD-2vr2A:
undetectable
3wrkD-2vr2A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x3e 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3


(Pseudomonas
aeruginosa)
PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III)
4 PHE A 114
LEU A 176
GLY A 122
VAL A  76
None
0.97A 3wrkD-2x3eA:
undetectable
3wrkD-2x3eA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xkr PUTATIVE CYTOCHROME
P450 142


(Mycobacterium
tuberculosis)
PF00067
(p450)
4 LEU A 226
GLY A 230
THR A 234
VAL A 277
HEM  A1400 (-4.4A)
PG4  A1399 ( 3.2A)
HEM  A1400 (-3.7A)
HEM  A1400 (-4.5A)
0.90A 3wrkD-2xkrA:
43.6
3wrkD-2xkrA:
28.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xkr PUTATIVE CYTOCHROME
P450 142


(Mycobacterium
tuberculosis)
PF00067
(p450)
4 LEU A 226
GLY A 230
THR A 234
VAL A 381
HEM  A1400 (-4.4A)
PG4  A1399 ( 3.2A)
HEM  A1400 (-3.7A)
None
0.42A 3wrkD-2xkrA:
43.6
3wrkD-2xkrA:
28.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aje PUTATIVE
UNCHARACTERIZED
PROTEIN ST1526


(Sulfurisphaera
tokodaii)
PF01300
(Sua5_yciO_yrdC)
PF03481
(SUA5)
4 PHE A 302
LEU A 245
GLY A 317
VAL A 294
None
0.90A 3wrkD-3ajeA:
undetectable
3wrkD-3ajeA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bol 5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE


(Thermotoga
maritima)
PF00809
(Pterin_bind)
PF02574
(S-methyl_trans)
4 PHE A 283
LEU A 249
GLY A 210
VAL A 231
None
0.98A 3wrkD-3bolA:
undetectable
3wrkD-3bolA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c2g SYS-1 PROTEIN

(Caenorhabditis
elegans)
no annotation 4 PHE A 294
LEU A 261
THR A 268
VAL A 280
None
1.02A 3wrkD-3c2gA:
undetectable
3wrkD-3c2gA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epm THIAMINE
BIOSYNTHESIS PROTEIN
THIC


(Caulobacter
vibrioides)
PF01964
(ThiC_Rad_SAM)
PF13667
(ThiC-associated)
4 LEU A 393
GLY A 397
THR A 400
VAL A 410
None
1.06A 3wrkD-3epmA:
undetectable
3wrkD-3epmA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gaz ALCOHOL
DEHYDROGENASE
SUPERFAMILY PROTEIN


(Novosphingobium
aromaticivorans)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 PHE A  85
GLY A  93
THR A  95
VAL A 111
None
1.01A 3wrkD-3gazA:
undetectable
3wrkD-3gazA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY


(Agrobacterium
fabrum)
PF13377
(Peripla_BP_3)
4 LEU A 120
GLY A 123
THR A  66
VAL A  68
None
1.08A 3wrkD-3gv0A:
undetectable
3wrkD-3gv0A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibj CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE


(Homo sapiens)
PF00233
(PDEase_I)
PF01590
(GAF)
PF13185
(GAF_2)
4 PHE A 370
LEU A 250
THR A 257
VAL A 365
None
0.94A 3wrkD-3ibjA:
undetectable
3wrkD-3ibjA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khy PROPIONATE KINASE

(Francisella
tularensis)
PF00871
(Acetate_kinase)
4 LEU A 201
GLY A 321
THR A 370
VAL A 181
None
0.93A 3wrkD-3khyA:
undetectable
3wrkD-3khyA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mc2 INHIBITOR OF
CARBONIC ANHYDRASE


(Mus musculus)
PF00405
(Transferrin)
4 PHE A 186
LEU A  66
GLY A 123
VAL A 154
None
0.78A 3wrkD-3mc2A:
undetectable
3wrkD-3mc2A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mn8 LP15968P

(Drosophila
melanogaster)
PF00246
(Peptidase_M14)
PF13620
(CarboxypepD_reg)
4 LEU A 285
GLY A 279
THR A 277
VAL A 222
GEM  A 601 (-4.0A)
GEM  A 601 (-3.3A)
None
None
1.04A 3wrkD-3mn8A:
undetectable
3wrkD-3mn8A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ng9 CAPSID PROTEIN

(Adeno-associated
dependoparvovirus
A)
PF00740
(Parvo_coat)
4 PHE A 292
LEU A 687
GLY A 306
VAL A 612
None
1.04A 3wrkD-3ng9A:
undetectable
3wrkD-3ng9A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o0k ALDO/KETO REDUCTASE

(Brucella
abortus)
PF00248
(Aldo_ket_red)
4 PHE A  90
LEU A 178
GLY A 156
VAL A 152
None
0.90A 3wrkD-3o0kA:
undetectable
3wrkD-3o0kA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ra2 CAPSID PROTEIN

(Adeno-associated
dependoparvovirus
A)
PF00740
(Parvo_coat)
4 PHE A 294
LEU A 689
GLY A 308
VAL A 614
None
1.06A 3wrkD-3ra2A:
undetectable
3wrkD-3ra2A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6p CAPSID PROTEIN

(Helicoverpa
armigera stunt
virus)
PF03566
(Peptidase_A21)
4 PHE A 514
LEU A 459
GLY A 266
THR A 439
None
1.04A 3wrkD-3s6pA:
undetectable
3wrkD-3s6pA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3shm CAPSID PROTEIN VP1

(Adeno-associated
dependoparvovirus
A)
PF00740
(Parvo_coat)
4 PHE A 292
LEU A 687
GLY A 306
VAL A 612
None
1.08A 3wrkD-3shmA:
undetectable
3wrkD-3shmA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3slc ACETATE KINASE

(Salmonella
enterica)
PF00871
(Acetate_kinase)
4 LEU A 211
GLY A 332
THR A 385
VAL A 189
None
1.06A 3wrkD-3slcA:
undetectable
3wrkD-3slcA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ta6 TRIOSEPHOSPHATE
ISOMERASE


(Mycobacterium
tuberculosis)
PF00121
(TIM)
4 PHE A 248
LEU A   6
GLY A 235
VAL A 219
None
1.00A 3wrkD-3ta6A:
undetectable
3wrkD-3ta6A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3upg OUTER MEMBRANE
PROTEIN C


(Salmonella
enterica)
PF00267
(Porin_1)
4 LEU A 107
GLY A 112
THR A 114
VAL A 287
None
1.00A 3wrkD-3upgA:
undetectable
3wrkD-3upgA:
19.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3zby P450 HEME-THIOLATE
PROTEIN


(Mycolicibacterium
smegmatis)
PF00067
(p450)
4 LEU A 229
GLY A 233
THR A 237
VAL A 280
HEM  A1402 ( 4.6A)
EDO  A1406 ( 3.4A)
HEM  A1402 (-3.7A)
HEM  A1402 (-4.4A)
0.89A 3wrkD-3zbyA:
43.2
3wrkD-3zbyA:
31.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3zby P450 HEME-THIOLATE
PROTEIN


(Mycolicibacterium
smegmatis)
PF00067
(p450)
4 LEU A 229
GLY A 233
THR A 237
VAL A 383
HEM  A1402 ( 4.6A)
EDO  A1406 ( 3.4A)
HEM  A1402 (-3.7A)
None
0.41A 3wrkD-3zbyA:
43.2
3wrkD-3zbyA:
31.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b0n POLYKETIDE SYNTHASE
III


(Ectocarpus
siliculosus)
PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C)
4 PHE A 165
LEU A 284
GLY A 193
VAL A 160
MLA  A1415 (-4.3A)
ACD  A1416 (-4.3A)
ACD  A1416 ( 4.3A)
None
1.03A 3wrkD-4b0nA:
undetectable
3wrkD-4b0nA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b90 DIHYDROPYRIMIDINASE-
RELATED PROTEIN 5


(Homo sapiens)
PF01979
(Amidohydro_1)
4 PHE A 373
GLY A  92
THR A 439
VAL A 403
None
1.05A 3wrkD-4b90A:
undetectable
3wrkD-4b90A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b92 DIHYDROPYRIMIDINASE-
RELATED PROTEIN 5


(Homo sapiens)
PF01979
(Amidohydro_1)
4 PHE A 373
GLY A  92
THR A 439
VAL A 403
None
1.01A 3wrkD-4b92A:
undetectable
3wrkD-4b92A:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c9m CYTOCHROME P450

(Novosphingobium
aromaticivorans)
PF00067
(p450)
4 LEU A 252
GLY A 256
THR A 260
VAL A 404
HEM  A1418 (-4.0A)
HEM  A1418 (-3.8A)
HEM  A1418 (-3.6A)
GOL  A1419 (-3.5A)
0.62A 3wrkD-4c9mA:
50.7
3wrkD-4c9mA:
45.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans)
PF00067
(p450)
5 PHE A  87
LEU A 250
GLY A 254
THR A 258
VAL A 301
None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
PEG  A 502 ( 4.5A)
1.47A 3wrkD-4dxyA:
54.0
3wrkD-4dxyA:
46.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans)
PF00067
(p450)
5 PHE A  87
LEU A 250
GLY A 254
THR A 258
VAL A 402
None
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
HEM  A 501 (-3.7A)
None
0.54A 3wrkD-4dxyA:
54.0
3wrkD-4dxyA:
46.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fwm PROPIONATE KINASE

(Salmonella
enterica)
PF00871
(Acetate_kinase)
4 LEU A 204
GLY A 325
THR A 379
VAL A 182
None
ATP  A 405 ( 4.5A)
None
None
0.99A 3wrkD-4fwmA:
undetectable
3wrkD-4fwmA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzi PROSTAGLANDIN F
SYNTHASE


(Trypanosoma
cruzi)
PF00248
(Aldo_ket_red)
4 PHE A 277
GLY A  85
THR A  89
VAL A  79
None
1.00A 3wrkD-4fziA:
undetectable
3wrkD-4fziA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g78 HISTIDINE
PHOSPHOTRANSFER
PROTEIN


(Medicago
truncatula)
PF01627
(Hpt)
4 PHE A 132
LEU A  21
GLY A  87
VAL A  43
None
1.07A 3wrkD-4g78A:
undetectable
3wrkD-4g78A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gz7 DIHYDROPYRIMIDINASE

(Tetraodon
nigroviridis)
PF01979
(Amidohydro_1)
4 PHE A 370
GLY A  89
THR A 436
VAL A 400
None
1.01A 3wrkD-4gz7A:
undetectable
3wrkD-4gz7A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hhr ALPHA-DIOXYGENASE

(Arabidopsis
thaliana)
PF03098
(An_peroxidase)
4 PHE A 549
LEU A  59
GLY A 335
VAL A 324
None
1.00A 3wrkD-4hhrA:
undetectable
3wrkD-4hhrA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyq PHOSPHOLIPASE A1

(Streptomyces
albidoflavus)
PF13472
(Lipase_GDSL_2)
4 LEU A 171
GLY A  81
THR A  58
VAL A 124
None
1.04A 3wrkD-4hyqA:
undetectable
3wrkD-4hyqA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ijn ACETATE KINASE

(Mycolicibacterium
smegmatis)
PF00871
(Acetate_kinase)
4 PHE A 132
LEU A 180
GLY A 201
VAL A 205
None
None
EDO  A 403 (-3.6A)
None
0.89A 3wrkD-4ijnA:
undetectable
3wrkD-4ijnA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq9 RIBOSE ABC
TRANSPORTER,
SUBSTRATE BINDING
PROTEIN


(Conexibacter
woesei)
PF13407
(Peripla_BP_4)
4 LEU A 244
GLY A 245
THR A 222
VAL A 177
None
1.04A 3wrkD-4kq9A:
undetectable
3wrkD-4kq9A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1m E3 UBIQUITIN-PROTEIN
LIGASE HERC2


(Homo sapiens)
PF00415
(RCC1)
4 PHE A 463
LEU A 482
GLY A 447
VAL A 453
None
1.08A 3wrkD-4l1mA:
undetectable
3wrkD-4l1mA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mfi SN-GLYCEROL-3-PHOSPH
ATE ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN USPB


(Mycobacterium
tuberculosis)
PF13416
(SBP_bac_8)
4 PHE A 339
LEU A  99
GLY A 308
VAL A 348
None
0.88A 3wrkD-4mfiA:
0.8
3wrkD-4mfiA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nte DEPH

(Chromobacterium
violaceum)
PF07992
(Pyr_redox_2)
4 PHE A 111
GLY A 238
THR A 260
VAL A 263
None
1.09A 3wrkD-4nteA:
undetectable
3wrkD-4nteA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nvt TRIOSEPHOSPHATE
ISOMERASE


(Brucella
melitensis)
PF00121
(TIM)
4 PHE A 244
LEU A   8
GLY A 231
VAL A 215
None
0.84A 3wrkD-4nvtA:
undetectable
3wrkD-4nvtA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q05 ESTERASE E25

(uncultured
bacterium)
PF07859
(Abhydrolase_3)
4 LEU A 210
GLY A 183
THR A 116
VAL A 164
None
0.98A 3wrkD-4q05A:
undetectable
3wrkD-4q05A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rjk ACETOLACTATE
SYNTHASE


(Bacillus
subtilis)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 PHE A 168
LEU A 126
GLY A  86
VAL A  83
None
1.08A 3wrkD-4rjkA:
undetectable
3wrkD-4rjkA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqt D-HYDANTOINASE

(Brucella suis)
PF01979
(Amidohydro_1)
4 PHE A 365
GLY A  87
THR A 431
VAL A 395
None
1.08A 3wrkD-4tqtA:
undetectable
3wrkD-4tqtA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tx8 PROBABLE CHITINASE A

(Chromobacterium
violaceum)
PF00704
(Glyco_hydro_18)
4 PHE A 386
LEU A 347
GLY A 370
VAL A  86
None
1.08A 3wrkD-4tx8A:
undetectable
3wrkD-4tx8A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ue0 FIBER

(Bovine
atadenovirus D)
no annotation 4 PHE A 467
LEU A 451
GLY A 437
VAL A 426
None
1.07A 3wrkD-4ue0A:
undetectable
3wrkD-4ue0A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y9a TRIOSEPHOSPHATE
ISOMERASE


(Streptomyces
coelicolor)
PF00121
(TIM)
4 PHE A 252
LEU A  10
GLY A 239
VAL A 223
None
1.01A 3wrkD-4y9aA:
undetectable
3wrkD-4y9aA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yet SUPEROXIDE DISMUTASE

(Babesia bovis)
PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C)
4 PHE A 107
LEU A 115
GLY A 124
VAL A 127
None
1.02A 3wrkD-4yetA:
undetectable
3wrkD-4yetA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ypg INTERFERON ALPHA-2

(Homo sapiens)
PF00143
(Interferon)
4 PHE C  38
GLY C  44
THR C  52
VAL C  55
None
1.03A 3wrkD-4ypgC:
undetectable
3wrkD-4ypgC:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5axh DEXTRANASE

(Thermoanaerobacter
pseudethanolicus)
PF13199
(Glyco_hydro_66)
4 PHE A 433
LEU A 442
GLY A 153
VAL A 404
None
0.97A 3wrkD-5axhA:
undetectable
3wrkD-5axhA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5by3 BTGH115A

(Bacteroides
thetaiotaomicron)
PF15979
(Glyco_hydro_115)
4 LEU A  78
GLY A  71
THR A 116
VAL A  40
None
1.00A 3wrkD-5by3A:
undetectable
3wrkD-5by3A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d39 SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION 6


(Homo sapiens)
PF00017
(SH2)
PF01017
(STAT_alpha)
PF02864
(STAT_bind)
4 PHE A 518
GLY A 468
THR A 465
VAL A 463
None
1.04A 3wrkD-5d39A:
undetectable
3wrkD-5d39A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fl7 ATP SYNTHASE SUBUNIT
ALPHA


(Yarrowia
lipolytica)
PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N)
4 PHE A 294
LEU A 347
GLY A 280
VAL A 258
None
0.94A 3wrkD-5fl7A:
undetectable
3wrkD-5fl7A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fyj GP41 ENV ECTODOMAIN
GP120 ENV ECTODOMAIN


(Human
immunodeficiency
virus 1;
Human
immunodeficiency
virus 1)
PF00517
(GP41)
PF00516
(GP120)
4 LEU G  86
GLY B 524
THR B 536
VAL B 539
None
0.75A 3wrkD-5fyjG:
undetectable
3wrkD-5fyjG:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j60 THIOREDOXIN
REDUCTASE


(Gloeobacter
violaceus)
PF07992
(Pyr_redox_2)
4 PHE A 247
GLY A 275
THR A 268
VAL A 252
FAD  A 401 ( 4.3A)
None
None
None
0.71A 3wrkD-5j60A:
undetectable
3wrkD-5j60A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j72 PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE
AMIDASE,AUTOLYSIN
CWP6


(Clostridioides
difficile)
PF01520
(Amidase_3)
PF04122
(CW_binding_2)
4 LEU A 329
GLY A 324
THR A 358
VAL A 362
None
1.05A 3wrkD-5j72A:
undetectable
3wrkD-5j72A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5knn ALANINE--TRNA
LIGASE, CYTOPLASMIC


(Homo sapiens)
PF01411
(tRNA-synt_2c)
4 PHE A 126
LEU A 101
GLY A 243
VAL A 250
None
None
A5A  A 500 (-3.4A)
None
1.08A 3wrkD-5knnA:
undetectable
3wrkD-5knnA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mu5 UNCHARACTERIZED
PROTEIN


(Magnetospirillum
magneticum)
no annotation 4 PHE A 629
LEU A 579
GLY A 596
VAL A  94
None
1.00A 3wrkD-5mu5A:
undetectable
3wrkD-5mu5A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nzg UDP-GLUCOSE
PYROPHOSPHORYLASE


(Leishmania
major)
no annotation 4 PHE A 242
LEU A 330
GLY A 192
VAL A 217
None
0.90A 3wrkD-5nzgA:
undetectable
3wrkD-5nzgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tir SUPEROXIDE DISMUTASE

(Trichoderma
reesei)
no annotation 4 PHE A 115
LEU A 123
GLY A 132
VAL A 135
None
1.03A 3wrkD-5tirA:
1.3
3wrkD-5tirA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1d ANTIGEN PEPTIDE
TRANSPORTER 1
ANTIGEN PEPTIDE
TRANSPORTER 2


(Homo sapiens;
Homo sapiens)
PF00005
(ABC_tran)
PF00664
(ABC_membrane)
PF00005
(ABC_tran)
PF00664
(ABC_membrane)
4 PHE B 189
LEU A 427
GLY A 431
THR A 435
None
1.07A 3wrkD-5u1dB:
1.7
3wrkD-5u1dB:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u84 ACID CERAMIDASE

(Balaenoptera
acutorostrata)
no annotation 4 PHE A 381
GLY A 203
THR A 186
VAL A  47
None
1.03A 3wrkD-5u84A:
undetectable
3wrkD-5u84A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u9p GLUCONATE
5-DEHYDROGENASE


(Burkholderia
cenocepacia)
PF13561
(adh_short_C2)
4 PHE A 194
GLY A 252
THR A 254
VAL A 149
None
1.01A 3wrkD-5u9pA:
undetectable
3wrkD-5u9pA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdu ENVELOPE
GLYCOPROTEIN GP160
ENVELOPE
GLYCOPROTEIN GP160


(Human
immunodeficiency
virus 1;
Human
immunodeficiency
virus 1)
no annotation
no annotation
4 LEU G  86
GLY A 524
THR A 536
VAL A 539
None
1.07A 3wrkD-5wduG:
undetectable
3wrkD-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwq FUNGAL CHITINASE
FROM RHIZOMUCOR
MIEHEI (NATIVE
PROTEIN)


(Rhizomucor
miehei)
no annotation 4 LEU A 305
GLY A 286
THR A 284
VAL A 258
None
1.04A 3wrkD-5xwqA:
undetectable
3wrkD-5xwqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE


(Trichomonas
vaginalis)
no annotation 4 PHE A  23
GLY A  73
THR A  59
VAL A 166
None
1.05A 3wrkD-5ybaA:
undetectable
3wrkD-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zh6 -

(-)
no annotation 4 PHE A  64
GLY A  32
THR A  34
VAL A 104
None
1.06A 3wrkD-5zh6A:
undetectable
3wrkD-5zh6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ax8 METHIONINE-TRNA
LIGASE


(Mycobacterium
tuberculosis)
no annotation 4 LEU A 475
GLY A 479
THR A 498
VAL A 374
None
1.08A 3wrkD-6ax8A:
undetectable
3wrkD-6ax8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b74 COAGULATION FACTOR
XII


(Homo sapiens)
no annotation 4 LEU B  20
GLY B  19
THR B 188
VAL B 160
None
0.91A 3wrkD-6b74B:
undetectable
3wrkD-6b74B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bme TRUNCATED HEMOGLOBIN
4


(Chlamydomonas
reinhardtii)
no annotation 4 PHE A 121
LEU A  34
GLY A  86
VAL A 141
None
1.01A 3wrkD-6bmeA:
undetectable
3wrkD-6bmeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MBH13 NADH
DEHYDROGENASE
SUBUNIT


(Pyrococcus
furiosus)
no annotation 4 LEU M 137
GLY M 133
THR M 218
VAL M 118
None
1.09A 3wrkD-6cfwM:
1.2
3wrkD-6cfwM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6emk SERINE/THREONINE-PRO
TEIN KINASE TOR2


(Saccharomyces
cerevisiae)
no annotation 4 PHE A2141
LEU A2273
GLY A2270
VAL A2292
None
0.99A 3wrkD-6emkA:
undetectable
3wrkD-6emkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g1i -

(-)
no annotation 4 PHE A 186
LEU A 291
GLY A 290
VAL A 183
None
0.99A 3wrkD-6g1iA:
undetectable
3wrkD-6g1iA:
undetectable