SIMILAR PATTERNS OF AMINO ACIDS FOR 3WRI_B_CAMB502_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a3x | PYRUVATE KINASE (Saccharomycescerevisiae) |
PF00224(PK)PF02887(PK_C) | 4 | GLY A 484THR A 453ILE A 460VAL A 456 | None | 0.90A | 3wriB-1a3xA:0.0 | 3wriB-1a3xA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d3u | TATA-BINDING PROTEIN (Pyrococcuswoesei) |
PF00352(TBP) | 4 | LEU A 117GLY A 136ILE A 156VAL A 157 | None | 0.90A | 3wriB-1d3uA:0.0 | 3wriB-1d3uA:18.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ddm | NUMB PROTEIN (Drosophilamelanogaster) |
PF00640(PID) | 4 | LEU A 109GLY A 176ILE A 139VAL A 140 | None | 0.89A | 3wriB-1ddmA:undetectable | 3wriB-1ddmA:15.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dub | 2-ENOYL-COAHYDRATASE (Rattusnorvegicus) |
PF00378(ECH_1) | 4 | GLY A 172THR A 176ILE A 165VAL A 192 | CAA A 300 (-3.2A)NoneNoneNone | 0.84A | 3wriB-1dubA:0.0 | 3wriB-1dubA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h5q | NADP-DEPENDENTMANNITOLDEHYDROGENASE (Agaricusbisporus) |
PF13561(adh_short_C2) | 4 | GLY A 123THR A 127ILE A 75VAL A 76 | None | 0.89A | 3wriB-1h5qA:undetectable | 3wriB-1h5qA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oyp | RIBONUCLEASE PH (Bacillussubtilis) |
PF01138(RNase_PH)PF03725(RNase_PH_C) | 4 | LEU A 241GLY A 142ILE A 112VAL A 43 | None | 0.86A | 3wriB-1oypA:undetectable | 3wriB-1oypA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1usy | ATPPHOSPHORIBOSYLTRANSFERASE (Thermotogamaritima) |
PF01634(HisG) | 4 | LEU E 4THR E 22ILE E 198VAL E 197 | None | 0.90A | 3wriB-1usyE:undetectable | 3wriB-1usyE:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uxc | FRUCTOSE REPRESSOR (Escherichiacoli) |
PF00356(LacI) | 4 | GLY A 11THR A 34ILE A 21VAL A 20 | None | 0.86A | 3wriB-1uxcA:undetectable | 3wriB-1uxcA:9.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x3l | HYPOTHETICAL PROTEINPH0495 (Pyrococcushorikoshii) |
PF05161(MOFRL)PF13660(DUF4147) | 4 | LEU A 415GLY A 414THR A 385ILE A 394 | None | 0.82A | 3wriB-1x3lA:undetectable | 3wriB-1x3lA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zh4 | KDP OPERONTRANSCRIPTIONALREGULATORY PROTEINKDPE (Escherichiacoli) |
PF00072(Response_reg) | 4 | LEU A 55GLY A 60ILE A 49VAL A 75 | None | 0.86A | 3wriB-1zh4A:undetectable | 3wriB-1zh4A:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fiq | PUTATIVE TAGATOSE6-PHOSPHATE KINASE 1 (Escherichiacoli) |
PF08013(Tagatose_6_P_K) | 4 | GLY A 281THR A 285ILE A 27VAL A 26 | None | 0.88A | 3wriB-2fiqA:undetectable | 3wriB-2fiqA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ha9 | UPF0210 PROTEINSP0239 (Streptococcuspneumoniae) |
PF05167(DUF711) | 4 | GLY A 313THR A 246ILE A 266VAL A 267 | None | 0.90A | 3wriB-2ha9A:undetectable | 3wriB-2ha9A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hnl | GLUTATHIONES-TRANSFERASE 1 (Onchocercavolvulus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | LEU A 102THR A 180ILE A 42VAL A 41 | None | 0.88A | 3wriB-2hnlA:undetectable | 3wriB-2hnlA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hq1 | GLUCOSE/RIBITOLDEHYDROGENASE (Ruminiclostridiumthermocellum) |
PF13561(adh_short_C2) | 4 | LEU A 25GLY A 224ILE A 140VAL A 183 | None | 0.86A | 3wriB-2hq1A:undetectable | 3wriB-2hq1A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i7h | NITROREDUCTASE-LIKEFAMILY PROTEIN (Bacillus cereus) |
PF00881(Nitroreductase) | 4 | LEU A 129GLY A 163THR A 89ILE A 55 | None | 0.90A | 3wriB-2i7hA:undetectable | 3wriB-2i7hA:20.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 5 | LEU A 244GLY A 248THR A 252ILE A 395VAL A 396 | HEM A 501 (-4.5A)HEM A 501 (-3.9A)HEM A 501 (-3.4A)NoneNone | 0.74A | 3wriB-2m56A:57.7 | 3wriB-2m56A:99.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m6k | FERRIENTEROBACTIN-BINDING PERIPLASMICPROTEIN (Escherichiacoli) |
PF01497(Peripla_BP_2) | 4 | GLY A 68THR A 54ILE A 65VAL A 64 | None | 0.72A | 3wriB-2m6kA:undetectable | 3wriB-2m6kA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nrr | UVRABC SYSTEMPROTEIN C (Thermotogamaritima) |
PF08459(UvrC_HhH_N) | 4 | LEU A 426GLY A 365THR A 487ILE A 368 | None | 0.86A | 3wriB-2nrrA:undetectable | 3wriB-2nrrA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nrx | UVRABC SYSTEMPROTEIN C (Thermotogamaritima) |
PF08459(UvrC_HhH_N) | 4 | LEU A 426GLY A 365THR A 487ILE A 368 | None | 0.82A | 3wriB-2nrxA:undetectable | 3wriB-2nrxA:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nvv | ACETYL-COAHYDROLASE/TRANSFERASE FAMILY PROTEIN (Porphyromonasgingivalis) |
PF02550(AcetylCoA_hydro)PF13336(AcetylCoA_hyd_C) | 4 | LEU A 330GLY A 304ILE A 291VAL A 290 | LEU A 330 ( 0.6A)GLY A 304 ( 0.0A)ILE A 291 ( 0.7A)VAL A 290 ( 0.6A) | 0.65A | 3wriB-2nvvA:undetectable | 3wriB-2nvvA:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qks | KIR3.1-PROKARYOTICKIR CHANNEL CHIMERA (Mus musculus;Paraburkholderiaxenovorans) |
PF01007(IRK) | 4 | LEU A 211GLY A 163ILE A 278VAL A 277 | None | 0.84A | 3wriB-2qksA:undetectable | 3wriB-2qksA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r09 | CYTOHESIN-3 (Mus musculus) |
PF00169(PH)PF01369(Sec7) | 4 | LEU A 88GLY A 84ILE A 116VAL A 115 | None | 0.77A | 3wriB-2r09A:undetectable | 3wriB-2r09A:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rb7 | PEPTIDASE,M20/M25/M40 FAMILY (Desulfovibrioalaskensis) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | LEU A 313GLY A 320THR A 290ILE A 170VAL A 169 | None | 1.39A | 3wriB-2rb7A:undetectable | 3wriB-2rb7A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | LEU A 226GLY A 230THR A 234VAL A 381 | HEM A1400 (-4.4A)PG4 A1399 ( 3.2A)HEM A1400 (-3.7A)None | 0.53A | 3wriB-2xkrA:45.3 | 3wriB-2xkrA:28.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y38 | LAMININ SUBUNITALPHA-5 (Mus musculus) |
PF00053(Laminin_EGF)PF00055(Laminin_N) | 4 | LEU A 201GLY A 205ILE A 219VAL A 218 | None | 0.71A | 3wriB-2y38A:undetectable | 3wriB-2y38A:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayx | MEMBRANE-BOUNDHYDROGENASE LARGESUBUNIT (Hydrogenovibriomarinus) |
PF00374(NiFeSe_Hases) | 4 | LEU A 459GLY A 464ILE A 282VAL A 281 | None | 0.87A | 3wriB-3ayxA:undetectable | 3wriB-3ayxA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3coi | MITOGEN-ACTIVATEDPROTEIN KINASE 13 (Homo sapiens) |
PF00069(Pkinase) | 4 | LEU A 171GLY A 170ILE A 85VAL A 84 | None | 0.90A | 3wriB-3coiA:undetectable | 3wriB-3coiA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3di4 | UNCHARACTERIZEDPROTEIN DUF1989 (Ruegeriapomeroyi) |
PF09347(DUF1989) | 4 | LEU A 83GLY A 232ILE A 70VAL A 258 | None | 0.90A | 3wriB-3di4A:undetectable | 3wriB-3di4A:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e0x | LIPASE-ESTERASERELATED PROTEIN (Clostridiumacetobutylicum) |
PF12146(Hydrolase_4) | 5 | LEU A 96GLY A 115THR A 199ILE A 191VAL A 192 | None | 1.33A | 3wriB-3e0xA:undetectable | 3wriB-3e0xA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3emq | ENDO-1,4-BETA-XYLANASE (Paenibacillusbarcinonensis) |
PF00331(Glyco_hydro_10) | 4 | LEU A 242GLY A 211THR A 182ILE A 227 | None | 0.82A | 3wriB-3emqA:undetectable | 3wriB-3emqA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f4f | DEOXYURIDINE5'-TRIPHOSPHATENUCLEOTIDOHYDROLASE (Saccharomycescerevisiae) |
PF00692(dUTPase) | 4 | LEU A 117GLY A 63ILE A 53VAL A 92 | NoneNoneNoneUMP A 200 (-3.6A) | 0.77A | 3wriB-3f4fA:undetectable | 3wriB-3f4fA:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fbg | PUTATIVE ARGINATELYASE (Staphylococcushaemolyticus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 157THR A 166ILE A 177VAL A 176 | None | 0.89A | 3wriB-3fbgA:undetectable | 3wriB-3fbgA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7l | ENDOGLUCANASE (Vibrioparahaemolyticus) |
PF00759(Glyco_hydro_9)PF02927(CelD_N) | 4 | GLY A 137THR A 163ILE A 170VAL A 166 | None | 0.88A | 3wriB-3h7lA:undetectable | 3wriB-3h7lA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hkv | POLY [ADP-RIBOSE]POLYMERASE 10 (Homo sapiens) |
PF00644(PARP) | 4 | LEU A 861GLY A 901ILE A 990VAL A 918 | None | 0.62A | 3wriB-3hkvA:undetectable | 3wriB-3hkvA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4k | MUCONATE LACTONIZINGENZYME (Corynebacteriumglutamicum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 360GLY A 359ILE A 48VAL A 47 | LEU A 360 ( 0.6A)GLY A 359 ( 0.0A)ILE A 48 ( 0.7A)VAL A 47 ( 0.6A) | 0.84A | 3wriB-3i4kA:undetectable | 3wriB-3i4kA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ic6 | PUTATIVE METHYLASEFAMILY PROTEIN (Neisseriagonorrhoeae) |
PF00588(SpoU_methylase) | 4 | LEU A 176GLY A 145ILE A 45VAL A 46 | None | 0.91A | 3wriB-3ic6A:undetectable | 3wriB-3ic6A:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3in6 | FMN-BINDING PROTEIN (Syntrophomonaswolfei) |
no annotation | 4 | LEU A 34GLY A 79ILE A 136VAL A 137 | NoneNoneMPD A 149 (-4.4A)None | 0.80A | 3wriB-3in6A:undetectable | 3wriB-3in6A:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kdn | RIBULOSEBISPHOSPHATECARBOXYLASE (Thermococcuskodakarensis) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | GLY A 368THR A 317ILE A 375VAL A 378 | CAP A 600 (-3.3A)NoneNoneNone | 0.89A | 3wriB-3kdnA:undetectable | 3wriB-3kdnA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lv8 | THYMIDYLATE KINASE (Vibrio cholerae) |
PF02223(Thymidylate_kin) | 4 | GLY A 42THR A 44ILE A 84VAL A 83 | None | 0.91A | 3wriB-3lv8A:undetectable | 3wriB-3lv8A:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mcq | THIAMINE-MONOPHOSPHATE KINASE (Methylobacillusflagellatus) |
PF00586(AIRS)PF02769(AIRS_C) | 4 | LEU A 114GLY A 117THR A 119ILE A 126 | None | 0.85A | 3wriB-3mcqA:undetectable | 3wriB-3mcqA:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ne5 | CATION EFFLUX SYSTEMPROTEIN CUSA (Escherichiacoli) |
PF00873(ACR_tran) | 4 | LEU A 492GLY A 488ILE A 379VAL A 380 | None | 0.54A | 3wriB-3ne5A:undetectable | 3wriB-3ne5A:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzq | BIOSYNTHETICARGININEDECARBOXYLASE (Escherichiacoli) |
PF02784(Orn_Arg_deC_N) | 4 | GLY A 362THR A 366ILE A 135VAL A 134 | SO4 A 701 (-3.5A)NoneNoneNone | 0.66A | 3wriB-3nzqA:undetectable | 3wriB-3nzqA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p48 | DEOXYURIDINE5'-TRIPHOSPHATENUCLEOTIDOHYDROLASE (Saccharomycescerevisiae) |
PF00692(dUTPase) | 4 | LEU A 117GLY A 63ILE A 53VAL A 92 | None | 0.81A | 3wriB-3p48A:undetectable | 3wriB-3p48A:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rim | TRANSKETOLASE (Mycobacteriumtuberculosis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | LEU A 135GLY A 136ILE A 174VAL A 173 | TPP A1002 (-3.9A)NoneNoneNone | 0.90A | 3wriB-3rimA:undetectable | 3wriB-3rimA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sju | KETO REDUCTASE (Streptomycesgriseoruber) |
PF00106(adh_short) | 4 | LEU A 24GLY A 235ILE A 140VAL A 183 | NoneNoneNDP A 301 (-4.3A)None | 0.85A | 3wriB-3sjuA:undetectable | 3wriB-3sjuA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tlk | FERRIENTEROBACTIN-BINDING PERIPLASMICPROTEIN (Escherichiacoli) |
PF01497(Peripla_BP_2) | 4 | GLY A 71THR A 57ILE A 68VAL A 67 | None | 0.73A | 3wriB-3tlkA:undetectable | 3wriB-3tlkA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3two | MANNITOLDEHYDROGENASE (Helicobacterpylori) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 152GLY A 68ILE A 144VAL A 143 | None | 0.87A | 3wriB-3twoA:undetectable | 3wriB-3twoA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uog | ALCOHOLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 158GLY A 182ILE A 194VAL A 195 | None | 0.85A | 3wriB-3uogA:undetectable | 3wriB-3uogA:23.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v0t | PERAKINE REDUCTASE (Rauvolfiaserpentina) |
PF00248(Aldo_ket_red) | 4 | GLY A 22THR A 281ILE A 40VAL A 39 | NoneATR A 338 (-3.0A)NoneNone | 0.90A | 3wriB-3v0tA:undetectable | 3wriB-3v0tA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vc1 | GERANYL DIPHOSPHATE2-C-METHYLTRANSFERASE (Streptomycescoelicolor) |
PF08241(Methyltransf_11) | 4 | LEU A 46GLY A 110ILE A 145VAL A 149 | None | 0.75A | 3wriB-3vc1A:undetectable | 3wriB-3vc1A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vue | GRANULE-BOUND STARCHSYNTHASE 1,CHLOROPLASTIC/AMYLOPLASTIC (Oryza sativa) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 4 | LEU A 388GLY A 474THR A 499ILE A 403 | None | 0.82A | 3wriB-3vueA:undetectable | 3wriB-3vueA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w1h | L-SERYL-TRNA(SEC)SELENIUM TRANSFERASE (Aquifexaeolicus) |
PF03841(SelA) | 4 | GLY A 288THR A 327ILE A 94VAL A 93 | LLP A 285 ( 3.8A)NoneNoneNone | 0.91A | 3wriB-3w1hA:undetectable | 3wriB-3w1hA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w1h | L-SERYL-TRNA(SEC)SELENIUM TRANSFERASE (Aquifexaeolicus) |
PF03841(SelA) | 4 | GLY A 289THR A 327ILE A 94VAL A 93 | None | 0.77A | 3wriB-3w1hA:undetectable | 3wriB-3w1hA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w1j | L-SERYL-TRNA(SEC)SELENIUM TRANSFERASE (Aquifexaeolicus) |
PF03841(SelA) | 4 | GLY A 289THR A 327ILE A 94VAL A 93 | None | 0.81A | 3wriB-3w1jA:undetectable | 3wriB-3w1jA:23.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3zby | P450 HEME-THIOLATEPROTEIN (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 4 | LEU A 229GLY A 233THR A 237VAL A 383 | HEM A1402 ( 4.6A)EDO A1406 ( 3.4A)HEM A1402 (-3.7A)None | 0.55A | 3wriB-3zbyA:44.3 | 3wriB-3zbyA:31.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bej | DYNAMIN 1-LIKEPROTEIN (Homo sapiens) |
PF00350(Dynamin_N)PF01031(Dynamin_M)PF02212(GED) | 4 | LEU A 269GLY A 281ILE A 214VAL A 213 | None | 0.85A | 3wriB-4bejA:undetectable | 3wriB-4bejA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bo6 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE FABG (Pseudomonasaeruginosa) |
PF13561(adh_short_C2) | 4 | LEU A 25GLY A 223ILE A 139VAL A 182 | None | 0.81A | 3wriB-4bo6A:undetectable | 3wriB-4bo6A:21.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c9m | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 5 | LEU A 252GLY A 256THR A 260ILE A 403VAL A 404 | HEM A1418 (-4.0A)HEM A1418 (-3.8A)HEM A1418 (-3.6A)NoneGOL A1419 (-3.5A) | 0.70A | 3wriB-4c9mA:51.6 | 3wriB-4c9mA:45.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d70 | SORTASE FAMILYPROTEIN (Clostridiumperfringens) |
PF04203(Sortase) | 4 | GLY A 59THR A 34ILE A 76VAL A 75 | None | 0.86A | 3wriB-4d70A:undetectable | 3wriB-4d70A:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ddi | UBIQUITIN-CONJUGATING ENZYME E2 D2,UBIQUITINTHIOESTERASE OTUB1 (Homo sapiens) |
PF00179(UQ_con)PF10275(Peptidase_C65) | 4 | LEU A1175GLY A1097ILE A1231VAL A1257 | None | 0.84A | 3wriB-4ddiA:undetectable | 3wriB-4ddiA:24.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dxy | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 4 | GLY A 254THR A 258ILE A 401VAL A 402 | PEG A 502 (-3.8A)HEM A 501 (-3.7A)NoneNone | 0.42A | 3wriB-4dxyA:54.9 | 3wriB-4dxyA:46.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dxy | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 4 | LEU A 250GLY A 254THR A 258VAL A 402 | HEM A 501 (-4.3A)PEG A 502 (-3.8A)HEM A 501 (-3.7A)None | 0.58A | 3wriB-4dxyA:54.9 | 3wriB-4dxyA:46.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eys | MCCC FAMILY PROTEIN (Streptococcuspneumoniae) |
PF02016(Peptidase_S66) | 4 | LEU A 246GLY A 207THR A 112ILE A 216 | None | 0.57A | 3wriB-4eysA:undetectable | 3wriB-4eysA:24.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4foz | PORIN D (Pseudomonasaeruginosa) |
PF03573(OprD) | 4 | LEU A 47GLY A 45THR A 43ILE A 412 | None | 0.88A | 3wriB-4fozA:undetectable | 3wriB-4fozA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fzw | 2,3-DEHYDROADIPYL-COA HYDRATASE (Escherichiacoli) |
PF00378(ECH_1) | 4 | GLY A 137THR A 141ILE A 130VAL A 157 | GOL A 301 ( 4.5A)NoneNoneNone | 0.86A | 3wriB-4fzwA:undetectable | 3wriB-4fzwA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hln | STARCH SYNTHASE I (Hordeum vulgare) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 4 | LEU A 407GLY A 493THR A 518ILE A 422 | None | 0.84A | 3wriB-4hlnA:undetectable | 3wriB-4hlnA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hpv | S-ADENOSYLMETHIONINESYNTHASE (Sulfolobussolfataricus) |
PF01941(AdoMet_Synthase) | 4 | GLY A 139THR A 94ILE A 111VAL A 107 | None | 0.81A | 3wriB-4hpvA:undetectable | 3wriB-4hpvA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i59 | CYCLOHEXYLAMINEOXIDASE (Microbacteriumoxydans) |
PF01593(Amino_oxidase) | 4 | LEU A 105GLY A 100ILE A 41VAL A 464 | NoneNoneFAD A 501 (-4.5A)None | 0.64A | 3wriB-4i59A:undetectable | 3wriB-4i59A:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4icq | AMINOPEPTIDASE PEPS (Streptococcuspneumoniae) |
PF02073(Peptidase_M29) | 4 | LEU A 222GLY A 265ILE A 292VAL A 293 | None | 0.92A | 3wriB-4icqA:undetectable | 3wriB-4icqA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k7g | 3-HYDROXYPROLINEDEHYDRATSE (Agrobacteriumvitis) |
PF05544(Pro_racemase) | 4 | GLY B 198THR B 202ILE B 176VAL B 175 | NoneNoneCIT B 901 (-4.2A)None | 0.89A | 3wriB-4k7gB:undetectable | 3wriB-4k7gB:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k8l | PROLINE RACEMASE (Ochrobactrumanthropi) |
PF05544(Pro_racemase) | 4 | GLY A 198THR A 202ILE A 176VAL A 175 | None | 0.84A | 3wriB-4k8lA:undetectable | 3wriB-4k8lA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kbx | UNCHARACTERIZEDPROTEIN YHFX (Escherichiacoli) |
PF01168(Ala_racemase_N) | 4 | LEU A 259GLY A 256ILE A 81VAL A 82 | NoneLLP A 61 ( 3.4A)NoneNone | 0.84A | 3wriB-4kbxA:undetectable | 3wriB-4kbxA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lji | CYTOCHROMEC-550-LIKE PROTEIN (Thermosynechococcuselongatus) |
PF14495(Cytochrom_C550) | 4 | GLY A 3THR A 37ILE A 9VAL A 8 | None | 0.92A | 3wriB-4ljiA:undetectable | 3wriB-4ljiA:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rvs | PROBABLE QUINONEREDUCTASE QOR(NADPH:QUINONEREDUCTASE)(ZETA-CRYSTALLINHOMOLOG PROTEIN) (Mycobacteriumtuberculosis) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 151THR A 160ILE A 171VAL A 170 | None | 0.76A | 3wriB-4rvsA:undetectable | 3wriB-4rvsA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s05 | DNA-BINDINGTRANSCRIPTIONALREGULATOR BASR (Klebsiellapneumoniae) |
PF00072(Response_reg)PF00486(Trans_reg_C) | 4 | LEU A 54GLY A 59ILE A 48VAL A 75 | None | 0.88A | 3wriB-4s05A:undetectable | 3wriB-4s05A:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tmk | PROTEIN (THYMIDYLATEKINASE) (Escherichiacoli) |
PF02223(Thymidylate_kin) | 4 | GLY A 42THR A 44ILE A 86VAL A 85 | None | 0.88A | 3wriB-4tmkA:undetectable | 3wriB-4tmkA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4woj | ASPARTATESEMIALDEHYDEDEHYDROGENASE (Francisellatularensis) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | LEU A 148GLY A 146ILE A 323VAL A 298 | None | 0.89A | 3wriB-4wojA:undetectable | 3wriB-4wojA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wr3 | ALANINE RACEMASE,BIOSYNTHETIC (Escherichiacoli) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | LEU A 241GLY A 268ILE A 297VAL A 298 | None | 0.88A | 3wriB-4wr3A:undetectable | 3wriB-4wr3A:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xbo | TRNA(CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ (Escherichiacoli) |
PF00588(SpoU_methylase) | 4 | LEU A 120GLY A 114ILE A 152VAL A 149 | SAH A 301 ( 4.8A)SAH A 301 (-2.9A)NoneNone | 0.86A | 3wriB-4xboA:undetectable | 3wriB-4xboA:24.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xei | ACTIN-RELATEDPROTEIN 2/3 COMPLEXSUBUNIT 3 (Bos taurus) |
PF04062(P21-Arc) | 4 | LEU E 133THR E 140ILE E 41VAL E 42 | None | 0.86A | 3wriB-4xeiE:2.4 | 3wriB-4xeiE:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgi | GLUTAMATEDEHYDROGENASE (Burkholderiathailandensis) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | LEU A 389GLY A 362ILE A 243VAL A 240 | NoneNoneNoneNAD A 500 (-4.0A) | 0.90A | 3wriB-4xgiA:undetectable | 3wriB-4xgiA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y23 | GAMMA GLUTAMYLTRANSPEPTIDASE,GAMMA-GLUTAMYLTRANSPEPTIDASE (Bacilluslicheniformis) |
PF01019(G_glu_transpept) | 4 | LEU A 60GLY A 64THR A 159ILE A 71 | None | 0.91A | 3wriB-4y23A:2.0 | 3wriB-4y23A:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a22 | VESICULAR STOMATITISVIRUS L POLYMERASE (Vesicularstomatitisvirus) |
PF00946(Mononeg_RNA_pol)PF14314(Methyltrans_Mon)PF14318(Mononeg_mRNAcap) | 4 | LEU A2073GLY A2078ILE A1938VAL A1964 | None | 0.87A | 3wriB-5a22A:undetectable | 3wriB-5a22A:11.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fi5 | TETRAHYDROALSTONINESYNTHASE (Catharanthusroseus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 154GLY A 80ILE A 146VAL A 145 | None | 0.88A | 3wriB-5fi5A:undetectable | 3wriB-5fi5A:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fl7 | ATP SYNTHASE SUBUNITBETAATP SYNTHASE SUBUNITGAMMA CHAIN,MITOCHONDRIAL (Yarrowialipolytica;Yarrowialipolytica) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N)PF00231(ATP-synt) | 4 | LEU G 292GLY D 304ILE D 47VAL D 50 | None | 0.81A | 3wriB-5fl7G:undetectable | 3wriB-5fl7G:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fyj | GP41 ENV ECTODOMAINGP120 ENV ECTODOMAIN (Humanimmunodeficiencyvirus 1;Humanimmunodeficiencyvirus 1) |
PF00517(GP41)PF00516(GP120) | 4 | LEU G 86GLY B 524THR B 536VAL B 539 | None | 0.85A | 3wriB-5fyjG:undetectable | 3wriB-5fyjG:19.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5kyo | CYP101J2 (Sphingobiumyanoikuyae) |
PF00067(p450) | 4 | GLY A 250THR A 254ILE A 397VAL A 398 | HEM A 501 (-3.8A)HEM A 501 (-3.5A)NoneNone | 0.42A | 3wriB-5kyoA:52.0 | 3wriB-5kyoA:40.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lx6 | POLY [ADP-RIBOSE]POLYMERASE 10 (Homo sapiens) |
PF00644(PARP) | 4 | LEU A 861GLY A 901ILE A 990VAL A 918 | None | 0.54A | 3wriB-5lx6A:undetectable | 3wriB-5lx6A:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t3b | GLYCOSIDE HYDROLASE (Bacteroidesplebeius) |
no annotation | 4 | LEU A 404GLY A 412ILE A 336VAL A 335 | None | 0.84A | 3wriB-5t3bA:undetectable | 3wriB-5t3bA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9c | DTDP-4-DEHYDRORHAMNOSE REDUCTASE (Yersiniaenterocolitica) |
PF04321(RmlD_sub_bind) | 4 | GLY A 10THR A 19ILE A 30VAL A 29 | None | 0.84A | 3wriB-5u9cA:undetectable | 3wriB-5u9cA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ugf | PURINE NUCLEOSIDEPHOSPHORYLASE (Homo sapiens) |
PF01048(PNP_UDP_1) | 4 | LEU A 35GLY A 264ILE A 241VAL A 126 | None | 0.84A | 3wriB-5ugfA:undetectable | 3wriB-5ugfA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyw | PYRUVATE CARBOXYLASE (Lactococcuslactis) |
PF00289(Biotin_carb_N)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | LEU A 911GLY A 909ILE A 926VAL A 927 | None | 0.85A | 3wriB-5vywA:undetectable | 3wriB-5vywA:17.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x8t | PROTEIN L3 (Spinaciaoleracea) |
PF00297(Ribosomal_L3) | 4 | GLY D 140THR D 124ILE D 163VAL D 162 | None | 0.85A | 3wriB-5x8tD:undetectable | 3wriB-5x8tD:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xlu | GAMMA GLUTAMYLTRANSPEPTIDASE (Bacilluslicheniformis) |
no annotation | 4 | LEU A 60GLY A 64THR A 159ILE A 71 | LEU A 60 ( 0.6A)GLY A 64 ( 0.0A)THR A 159 ( 0.8A)ILE A 71 ( 0.7A) | 0.92A | 3wriB-5xluA:undetectable | 3wriB-5xluA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xww | AMPHB (Streptomycesnodosus) |
no annotation | 4 | LEU A 323GLY A 366ILE A 150VAL A 149 | None | 0.71A | 3wriB-5xwwA:undetectable | 3wriB-5xwwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z06 | BDI_3064 PROTEIN (Parabacteroidesdistasonis) |
no annotation | 4 | LEU A 415GLY A 418ILE A 350VAL A 351 | None | 0.89A | 3wriB-5z06A:undetectable | 3wriB-5z06A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6at7 | PHENYLALANINEAMMONIA-LYASE (Sorghum bicolor) |
no annotation | 4 | LEU A 255GLY A 252THR A 188ILE A 463 | NoneNoneMDO A 190 ( 4.4A)None | 0.91A | 3wriB-6at7A:undetectable | 3wriB-6at7A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b74 | COAGULATION FACTORXII (Homo sapiens) |
no annotation | 4 | LEU B 20GLY B 19THR B 188VAL B 160 | None | 0.86A | 3wriB-6b74B:undetectable | 3wriB-6b74B:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bbp | CYTOHESIN-3,ADP-RIBOSYLATION FACTOR 6 (Homo sapiens;Mus musculus) |
no annotation | 4 | LEU A 88GLY A 84ILE A 116VAL A 115 | None | 0.77A | 3wriB-6bbpA:1.9 | 3wriB-6bbpA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6e9p | - (-) |
no annotation | 4 | LEU A 12GLY A 131ILE A 96VAL A 93 | None | 0.91A | 3wriB-6e9pA:undetectable | 3wriB-6e9pA:undetectable |