SIMILAR PATTERNS OF AMINO ACIDS FOR 3WQV_A_GCSA501_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cnv | CONCANAVALIN B (Canavaliaensiformis) |
PF00704(Glyco_hydro_18) | 5 | PHE A 35GLY A 85ASP A 129TYR A 189TRP A 265 | None | 0.53A | 3wqvA-1cnvA:19.5 | 3wqvA-1cnvA:25.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2k | CHITINASE 1 (Coccidioidesimmitis) |
PF00704(Glyco_hydro_18) | 8 | PHE A 71GLY A 130ASP A 169GLU A 171MET A 237TYR A 239TYR A 293TRP A 378 | None | 0.80A | 3wqvA-1d2kA:44.0 | 3wqvA-1d2kA:27.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2k | CHITINASE 1 (Coccidioidesimmitis) |
PF00704(Glyco_hydro_18) | 9 | PHE A 71GLY A 130GLU A 171MET A 237TYR A 239ASP A 240TYR A 293ARG A 295TRP A 378 | None | 0.54A | 3wqvA-1d2kA:44.0 | 3wqvA-1d2kA:27.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2k | CHITINASE 1 (Coccidioidesimmitis) |
PF00704(Glyco_hydro_18) | 6 | PHE A 71GLY A 130TRP A 131ASP A 169GLU A 171TYR A 293 | None | 1.02A | 3wqvA-1d2kA:44.0 | 3wqvA-1d2kA:27.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2k | CHITINASE 1 (Coccidioidesimmitis) |
PF00704(Glyco_hydro_18) | 7 | PHE A 71GLY A 130TRP A 131GLU A 171ASP A 240TYR A 293ARG A 295 | None | 0.81A | 3wqvA-1d2kA:44.0 | 3wqvA-1d2kA:27.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6z | CHITINASE B (Serratiamarcescens) |
PF00704(Glyco_hydro_18) | 11 | PHE A 51GLY A 96TRP A 97ASP A 142GLU A 144MET A 212TYR A 214ASP A 215TYR A 292ARG A 294TRP A 403 | NGO A 502 (-4.7A)NGO A 502 ( 3.8A)NAG A 503 ( 3.7A)NGO A 502 (-3.1A)NGO A 502 (-3.4A)NGO A 502 (-3.4A)NGO A 502 (-4.5A)NGO A 502 ( 3.1A)NGO A 502 (-4.8A)NAG A 503 ( 4.9A)NGO A 502 (-3.5A) | 0.51A | 3wqvA-1e6zA:41.6 | 3wqvA-1e6zA:25.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hjv | CHITINASE-3 LIKEPROTEIN 1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 8 | PHE A 58GLY A 98TRP A 99MET A 204TYR A 206ASP A 207ARG A 263TRP A 352 | NAG A -2 (-4.7A)NAG A -2 ( 4.2A)NAG A 1 (-3.6A)NAG A 1 (-3.7A)NAG A -1 (-4.6A)NAG A -1 (-3.7A)NAG A -2 (-4.2A)NAG A -1 (-3.5A) | 0.48A | 3wqvA-1hjvA:52.1 | 3wqvA-1hjvA:37.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hkk | CHITOTRIOSIDASE-1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 11 | PHE A 58GLY A 98TRP A 99ASP A 138GLU A 140MET A 210TYR A 212ASP A 213TYR A 267ARG A 269TRP A 358 | AMI A1388 (-4.8A)AMI A1388 ( 3.7A)NAA A1390 ( 4.3A)AMI A1388 (-3.1A)AMI A1388 ( 3.3A)AMI A1388 (-3.3A)AMI A1388 (-4.8A)AMI A1388 ( 2.9A)NAA A1387 (-3.6A)NAA A1389 (-3.2A)AMI A1388 (-3.5A) | 0.47A | 3wqvA-1hkkA:55.2 | 3wqvA-1hkkA:39.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1itx | GLYCOSYL HYDROLASE (Bacilluscirculans) |
PF00704(Glyco_hydro_18) | 7 | PHE A 77GLY A 163ASP A 202TYR A 279ASP A 280TYR A 338TRP A 433 | GOL A1007 (-4.8A)GOL A1007 ( 3.9A)GOL A1007 (-3.6A)GOL A1007 ( 4.8A)NoneNoneGOL A1007 (-4.8A) | 0.83A | 3wqvA-1itxA:48.8 | 3wqvA-1itxA:32.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1itx | GLYCOSYL HYDROLASE (Bacilluscirculans) |
PF00704(Glyco_hydro_18) | 10 | PHE A 77GLY A 163TRP A 164GLU A 204MET A 277TYR A 279ASP A 280TYR A 338ARG A 340TRP A 433 | GOL A1007 (-4.8A)GOL A1007 ( 3.9A)NoneGOL A1007 (-3.7A)GOL A1007 ( 3.3A)GOL A1007 ( 4.8A)NoneNoneNoneGOL A1007 (-4.8A) | 0.58A | 3wqvA-1itxA:48.8 | 3wqvA-1itxA:32.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kfw | CHITINASE B (Arthrobactersp. TAD20) |
PF00704(Glyco_hydro_18) | 7 | PHE A 55GLY A 135ASP A 190TYR A 271ASP A 272TYR A 328TRP A 412 | NoneNoneNoneGOL A 530 (-4.8A)GOL A 530 (-3.7A)NoneNone | 0.78A | 3wqvA-1kfwA:44.7 | 3wqvA-1kfwA:26.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kfw | CHITINASE B (Arthrobactersp. TAD20) |
PF00704(Glyco_hydro_18) | 9 | PHE A 55GLY A 135TRP A 136GLU A 192TYR A 271ASP A 272TYR A 328ARG A 330TRP A 412 | NoneNoneNoneGOL A 530 (-3.9A)GOL A 530 (-4.8A)GOL A 530 (-3.7A)NoneNoneNone | 0.49A | 3wqvA-1kfwA:44.7 | 3wqvA-1kfwA:26.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ljy | MGP-40 (Capra hircus) |
PF00704(Glyco_hydro_18) | 6 | PHE A 37GLY A 77TYR A 185ASP A 186ARG A 242TRP A 331 | None | 1.15A | 3wqvA-1ljyA:51.8 | 3wqvA-1ljyA:35.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1vf8 | SECRETORY PROTEIN (Mus musculus) |
PF00704(Glyco_hydro_18) | 7 | PHE A 37GLY A 77TRP A 78ASP A 117ASP A 192TYR A 246TRP A 339 | None | 0.83A | 3wqvA-1vf8A:54.8 | 3wqvA-1vf8A:37.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1vf8 | SECRETORY PROTEIN (Mus musculus) |
PF00704(Glyco_hydro_18) | 8 | PHE A 37GLY A 77TRP A 78ASP A 117MET A 189TYR A 191ASP A 192TYR A 246 | None | 0.49A | 3wqvA-1vf8A:54.8 | 3wqvA-1vf8A:37.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1wb0 | CHITOTRIOSIDASE 1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 11 | PHE A 58GLY A 98TRP A 99ASP A 138GLU A 140MET A 210TYR A 212ASP A 213TYR A 267ARG A 269TRP A 360 | None | 0.47A | 3wqvA-1wb0A:55.1 | 3wqvA-1wb0A:34.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wno | CHITINASE (Aspergillusfumigatus) |
PF00704(Glyco_hydro_18) | 9 | PHE A 38GLY A 98ASP A 137GLU A 139MET A 205TYR A 207ASP A 208TYR A 261TRP A 346 | None | 0.76A | 3wqvA-1wnoA:43.8 | 3wqvA-1wnoA:29.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wno | CHITINASE (Aspergillusfumigatus) |
PF00704(Glyco_hydro_18) | 10 | PHE A 38GLY A 98TRP A 99GLU A 139MET A 205TYR A 207ASP A 208TYR A 261ARG A 263TRP A 346 | None | 0.54A | 3wqvA-1wnoA:43.8 | 3wqvA-1wnoA:29.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsj | PROTEIN PPL-2 (Parkiaplatycephala) |
PF00704(Glyco_hydro_18) | 6 | PHE A 32GLY A 80ASP A 125GLU A 127TYR A 182TRP A 253 | None | 0.53A | 3wqvA-2gsjA:19.7 | 3wqvA-2gsjA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uy3 | ENDOCHITINASE (Saccharomycescerevisiae) |
PF00704(Glyco_hydro_18) | 6 | PHE A 60GLY A 109ASP A 155GLU A 157TYR A 214TRP A 285 | H33 A1311 (-4.3A)H33 A1311 ( 3.8A)H33 A1311 (-3.0A)H33 A1311 (-3.7A)H33 A1311 (-4.7A)H33 A1311 (-3.5A) | 0.56A | 3wqvA-2uy3A:20.0 | 3wqvA-2uy3A:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wk2 | CHITINASE A (Serratiamarcescens) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 11 | PHE A 191GLY A 274TRP A 275ASP A 313GLU A 315MET A 388TYR A 390ASP A 391TYR A 444ARG A 446TRP A 539 | SN5 A1564 (-4.6A)NGT A1565 ( 3.9A)SN5 A1566 (-3.3A)NGT A1565 (-3.4A)SN5 A1566 ( 2.9A)NGT A1565 (-3.7A)NGT A1565 (-4.7A)NGT A1565 (-2.9A)NGT A1565 ( 4.9A)SN5 A1566 ( 3.5A)NGT A1565 ( 3.5A) | 0.49A | 3wqvA-2wk2A:42.8 | 3wqvA-2wk2A:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvn | ASPERGILLUSFUMIGATUS CHITINASEA1 (Aspergillusfumigatus) |
PF00704(Glyco_hydro_18) | 6 | PHE A 60GLY A 123ASP A 172GLU A 174TYR A 232TRP A 312 | NoneNoneKLS A1338 (-2.8A)KLS A1338 (-2.9A)KLS A1338 (-4.8A)KLS A1338 (-3.5A) | 0.55A | 3wqvA-2xvnA:20.9 | 3wqvA-2xvnA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y8v | CLASS III CHITINASE,PUTATIVE (Aspergillusfumigatus) |
PF00704(Glyco_hydro_18) | 5 | GLY A 92ASP A 130GLU A 132TYR A 196TRP A 262 | None | 0.46A | 3wqvA-2y8vA:19.1 | 3wqvA-2y8vA:21.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ybu | ACIDIC MAMMALIANCHITINASE (Homo sapiens) |
PF00704(Glyco_hydro_18) | 10 | PHE A 58GLY A 98TRP A 99ASP A 138GLU A 140MET A 210TYR A 212ASP A 213TYR A 267TRP A 360 | CX9 A1398 (-4.5A)CX9 A1398 (-3.5A)CX9 A1399 ( 3.4A)CX9 A1398 (-3.0A)CX9 A1398 (-3.7A)CX9 A1398 (-3.3A)CX9 A1398 (-4.3A)CX9 A1398 ( 4.4A)NoneCX9 A1398 ( 3.3A) | 0.40A | 3wqvA-2ybuA:55.9 | 3wqvA-2ybuA:43.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afb | PUTATIVE CHITINASE (Pyrococcusfuriosus) |
no annotation | 5 | PHE A 448GLY A 489GLU A 526ASP A 636TRP A 664 | GOL A 2 (-4.6A)GOL A 2 ( 3.7A)GOL A 2 (-3.7A)GOL A 718 ( 3.8A)GOL A 2 (-3.8A) | 0.62A | 3wqvA-3afbA:20.4 | 3wqvA-3afbA:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afb | PUTATIVE CHITINASE (Pyrococcusfuriosus) |
no annotation | 6 | PHE A 448GLY A 489GLU A 526MET A 585ASP A 588TRP A 664 | GOL A 2 (-4.6A)GOL A 2 ( 3.7A)GOL A 2 (-3.7A)GOL A 2 ( 4.4A)NoneGOL A 2 (-3.8A) | 0.76A | 3wqvA-3afbA:20.4 | 3wqvA-3afbA:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3alf | CHITINASE, CLASS V (Nicotianatabacum) |
PF00704(Glyco_hydro_18) | 6 | GLY A 74GLU A 115MET A 181TYR A 183TYR A 234TRP A 326 | NoneEDO A 357 (-2.8A)EDO A 357 ( 3.3A)EDO A 359 ( 4.7A)NoneEDO A 357 (-4.4A) | 1.08A | 3wqvA-3alfA:45.1 | 3wqvA-3alfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3alf | CHITINASE, CLASS V (Nicotianatabacum) |
PF00704(Glyco_hydro_18) | 7 | PHE A 31GLY A 73ASP A 113TYR A 183ASP A 184TYR A 234TRP A 326 | EDO A 357 (-4.8A)EDO A 357 ( 4.2A)EDO A 357 (-4.2A)EDO A 359 ( 4.7A)EDO A 359 (-4.5A)NoneEDO A 357 (-4.4A) | 0.79A | 3wqvA-3alfA:45.1 | 3wqvA-3alfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3alf | CHITINASE, CLASS V (Nicotianatabacum) |
PF00704(Glyco_hydro_18) | 8 | PHE A 31GLY A 73GLU A 115MET A 181TYR A 183ASP A 184TYR A 234TRP A 326 | EDO A 357 (-4.8A)EDO A 357 ( 4.2A)EDO A 357 (-2.8A)EDO A 357 ( 3.3A)EDO A 359 ( 4.7A)EDO A 359 (-4.5A)NoneEDO A 357 (-4.4A) | 0.37A | 3wqvA-3alfA:45.1 | 3wqvA-3alfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqu | AT4G19810 (Arabidopsisthaliana) |
PF00704(Glyco_hydro_18) | 7 | GLY A 75GLU A 116MET A 182TYR A 184ASP A 185TYR A 235TRP A 324 | None | 1.09A | 3wqvA-3aquA:43.9 | 3wqvA-3aquA:27.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqu | AT4G19810 (Arabidopsisthaliana) |
PF00704(Glyco_hydro_18) | 9 | PHE A 32GLY A 74ASP A 114GLU A 116MET A 182TYR A 184ASP A 185TYR A 235TRP A 324 | None | 0.71A | 3wqvA-3aquA:43.9 | 3wqvA-3aquA:27.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9e | CHITINASE A (Vibrio harveyi) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 9 | PHE A 192GLY A 274ASP A 313MET A 389TYR A 391ASP A 392TYR A 461ARG A 463TRP A 570 | None | 0.73A | 3wqvA-3b9eA:39.9 | 3wqvA-3b9eA:25.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9e | CHITINASE A (Vibrio harveyi) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 9 | PHE A 192GLY A 274TRP A 275MET A 389TYR A 391ASP A 392TYR A 461ARG A 463TRP A 570 | None | 0.54A | 3wqvA-3b9eA:39.9 | 3wqvA-3b9eA:25.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cz8 | PUTATIVESPORULATION-SPECIFICGLYCOSYLASE YDHD (Bacillussubtilis) |
PF00704(Glyco_hydro_18) | 5 | PHE A 131ASP A 210GLU A 212TYR A 275ASP A 276 | GOL A 502 ( 4.7A)GOL A 502 (-3.4A)GOL A 502 (-3.4A)NoneNone | 0.97A | 3wqvA-3cz8A:26.9 | 3wqvA-3cz8A:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cz8 | PUTATIVESPORULATION-SPECIFICGLYCOSYLASE YDHD (Bacillussubtilis) |
PF00704(Glyco_hydro_18) | 5 | PHE A 131ASP A 210GLU A 212TYR A 275TRP A 398 | GOL A 502 ( 4.7A)GOL A 502 (-3.4A)GOL A 502 (-3.4A)NoneNone | 1.10A | 3wqvA-3cz8A:26.9 | 3wqvA-3cz8A:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ebv | CHINITASE A (Streptomycescoelicolor) |
PF00704(Glyco_hydro_18) | 6 | PHE A 37GLY A 84ASP A 119GLU A 121TYR A 181TRP A 271 | None | 0.48A | 3wqvA-3ebvA:23.1 | 3wqvA-3ebvA:25.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fnd | CHITINASE (Bacteroidesthetaiotaomicron) |
PF00704(Glyco_hydro_18) | 8 | PHE A 79ASP A 155GLU A 157MET A 211TYR A 213ASP A 214TYR A 256TRP A 322 | NoneNoneNoneNoneNoneNoneGOL A 356 (-4.3A)None | 0.47A | 3wqvA-3fndA:33.5 | 3wqvA-3fndA:27.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g6l | CHITINASE (Clonostachysrosea) |
PF00704(Glyco_hydro_18) | 7 | PHE A 74GLY A 133ASP A 172MET A 240TYR A 242ASP A 243TRP A 381 | None | 0.87A | 3wqvA-3g6lA:43.8 | 3wqvA-3g6lA:27.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g6l | CHITINASE (Clonostachysrosea) |
PF00704(Glyco_hydro_18) | 10 | PHE A 74GLY A 133TRP A 134GLU A 174MET A 240TYR A 242ASP A 243TYR A 296ARG A 298TRP A 381 | None | 0.66A | 3wqvA-3g6lA:43.8 | 3wqvA-3g6lA:27.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ian | CHITINASE (Lactococcuslactis) |
PF00704(Glyco_hydro_18) | 5 | PHE A 84GLY A 126ASP A 160TYR A 229TRP A 321 | NoneEDO A 369 ( 3.7A)EDO A 361 ( 2.7A)EDO A 361 (-4.5A)EDO A 361 (-4.5A) | 0.55A | 3wqvA-3ianA:21.3 | 3wqvA-3ianA:25.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qok | PUTATIVE CHITINASEII (Klebsiellapneumoniae) |
PF00704(Glyco_hydro_18) | 8 | PHE A 58GLY A 113ASP A 151MET A 220TYR A 222ASP A 223TYR A 276TRP A 395 | None | 0.81A | 3wqvA-3qokA:41.1 | 3wqvA-3qokA:29.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qok | PUTATIVE CHITINASEII (Klebsiellapneumoniae) |
PF00704(Glyco_hydro_18) | 10 | PHE A 58GLY A 113TRP A 114GLU A 153MET A 220TYR A 222ASP A 223TYR A 276ARG A 278TRP A 395 | None | 0.46A | 3wqvA-3qokA:41.1 | 3wqvA-3qokA:29.59 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w4r | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18) | 6 | PHE A 61GLY A 106ASP A 146TYR A 217TYR A 272TRP A 372 | None | 0.78A | 3wqvA-3w4rA:69.8 | 3wqvA-3w4rA:72.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w4r | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18) | 10 | PHE A 61GLY A 106TRP A 107GLU A 148MET A 215TYR A 217ASP A 218TYR A 272ARG A 274TRP A 372 | None | 0.25A | 3wqvA-3w4rA:69.8 | 3wqvA-3w4rA:72.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w5n | PUTATIVERHAMNOSIDASE (Streptomycesavermitilis) |
PF05592(Bac_rhamnosid)PF08531(Bac_rhamnosid_N)PF17389(Bac_rhamnosid6H)PF17390(Bac_rhamnosid_C) | 5 | GLY A 639ASP A 349TYR A 393ARG A 351TRP A 347 | NoneNoneRAM A1206 (-3.8A)RAM A1206 (-3.0A)None | 1.36A | 3wqvA-3w5nA:undetectable | 3wqvA-3w5nA:17.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3wl1 | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18) | 11 | PHE A 61GLY A 106TRP A 107ASP A 146GLU A 148MET A 215TYR A 217ASP A 218TYR A 272ARG A 274TRP A 372 | NAG A 501 (-4.5A)NAG A 501 (-3.6A)NAG A 505 ( 3.4A)NAG A 501 (-3.0A)NAG A 501 (-2.7A)NAG A 501 (-3.5A)NAG A 501 (-4.6A)NAG A 501 ( 3.2A)NAG A 502 (-3.9A)NAG A 505 ( 3.6A)NAG A 501 (-3.7A) | 0.21A | 3wqvA-3wl1A:70.1 | 3wqvA-3wl1A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5q | CHI1 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 8 | PHE A 117GLY A 214GLU A 256MET A 323TYR A 325ASP A 326TYR A 379ARG A 381 | None | 0.90A | 3wqvA-4a5qA:33.8 | 3wqvA-4a5qA:25.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5q | CHI1 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 9 | PHE A 117GLY A 214TRP A 215GLU A 256MET A 323ASP A 326TYR A 379ARG A 381TRP A 486 | None | 0.90A | 3wqvA-4a5qA:33.8 | 3wqvA-4a5qA:25.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ac1 | ENDO-N-ACETYL-BETA-D-GLUCOSAMINIDASE (Trichodermareesei) |
PF00704(Glyco_hydro_18) | 5 | GLY X 88ASP X 129GLU X 131TYR X 195TRP X 259 | ZN X1291 ( 4.5A)ACT X1288 (-2.9A) ZN X1291 (-2.5A)ACT X1288 (-4.7A)ACT X1288 (-4.0A) | 0.57A | 3wqvA-4ac1X:21.7 | 3wqvA-4ac1X:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4axn | CHITINASE C1 (Serratiamarcescens) |
PF00704(Glyco_hydro_18) | 5 | PHE A 66GLY A 105ASP A 139TYR A 208TRP A 300 | NoneNoneACT A1331 (-2.7A)ACT A1331 (-4.6A)ACT A1330 ( 4.1A) | 0.60A | 3wqvA-4axnA:20.6 | 3wqvA-4axnA:22.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ay1 | CHITINASE-3-LIKEPROTEIN 2 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 5 | PHE A 63GLY A 103ASP A 213TYR A 269TRP A 360 | NoneNAG A 401 (-3.5A)NAG A 401 (-2.8A)NAG A 400 (-3.7A)NAG A 401 (-3.7A) | 0.40A | 3wqvA-4ay1A:51.4 | 3wqvA-4ay1A:35.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dws | CHI2 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 6 | PHE A 200GLY A 307ASP A 347ASP A 425TYR A 482TRP A 582 | NoneNoneNoneNoneNoneGOL A 701 (-4.2A) | 1.14A | 3wqvA-4dwsA:34.1 | 3wqvA-4dwsA:24.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dws | CHI2 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 7 | PHE A 200GLY A 307ASP A 347MET A 422TYR A 424ASP A 425TYR A 482 | None | 0.84A | 3wqvA-4dwsA:34.1 | 3wqvA-4dwsA:24.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dws | CHI2 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 8 | PHE A 200GLY A 307TRP A 308GLU A 349ASP A 425TYR A 482ARG A 484TRP A 582 | NoneNoneNoneNoneNoneNoneNoneGOL A 701 (-4.2A) | 0.83A | 3wqvA-4dwsA:34.1 | 3wqvA-4dwsA:24.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dws | CHI2 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 9 | PHE A 200GLY A 307TRP A 308GLU A 349MET A 422TYR A 424ASP A 425TYR A 482ARG A 484 | None | 0.58A | 3wqvA-4dwsA:34.1 | 3wqvA-4dwsA:24.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl3 | PUTATIVEGLUCOAMYLASE (Bacteroidesuniformis) |
PF10091(Glycoamylase) | 5 | GLY A 333ASP A 334TYR A 318ASP A 345TYR A 321 | None | 1.29A | 3wqvA-4gl3A:undetectable | 3wqvA-4gl3A:25.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mb5 | CHITINASE 60 (Moritellamarina) |
PF00704(Glyco_hydro_18)PF16403(DUF5011) | 5 | PHE A 70GLY A 117ASP A 151TYR A 220TRP A 311 | NAG A 608 (-4.4A)NAG A 608 ( 3.9A)NAG A 608 (-3.4A)NAG A 609 (-4.4A)NAG A 608 (-3.5A) | 0.39A | 3wqvA-4mb5A:21.5 | 3wqvA-4mb5A:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnm | CHITINASE A (Cycas revoluta) |
PF00704(Glyco_hydro_18) | 8 | PHE A 34GLY A 76ASP A 117MET A 189TYR A 191ASP A 192ARG A 242TRP A 327 | None | 0.44A | 3wqvA-4mnmA:43.8 | 3wqvA-4mnmA:29.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) |
PF00704(Glyco_hydro_18) | 7 | PHE A 58GLY A 113ASP A 151GLU A 153TYR A 325ARG A 278TRP A 395 | NoneACT A 502 ( 4.6A)ACT A 502 (-3.0A)ACT A 502 (-3.8A)NoneGOL A 504 (-4.1A)GOL A 504 (-3.7A) | 1.48A | 3wqvA-4q22A:41.2 | 3wqvA-4q22A:29.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) |
PF00704(Glyco_hydro_18) | 11 | PHE A 58GLY A 113TRP A 114ASP A 151GLU A 153MET A 220TYR A 222ASP A 223TYR A 276ARG A 278TRP A 395 | NoneACT A 502 ( 4.6A)NoneACT A 502 (-3.0A)ACT A 502 (-3.8A)ACT A 502 ( 3.1A)GOL A 504 ( 4.6A)GOL A 504 (-2.7A)GOL A 504 ( 4.7A)GOL A 504 (-4.1A)GOL A 504 (-3.7A) | 0.40A | 3wqvA-4q22A:41.2 | 3wqvA-4q22A:29.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6t | GLYCOSYL HYDROLASE,FAMILY 18 (Pseudomonasprotegens) |
PF00704(Glyco_hydro_18) | 5 | ASP A 147GLU A 149MET A 211TYR A 213ARG A 272 | None | 1.19A | 3wqvA-4q6tA:33.4 | 3wqvA-4q6tA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6t | GLYCOSYL HYDROLASE,FAMILY 18 (Pseudomonasprotegens) |
PF00704(Glyco_hydro_18) | 7 | ASP A 147GLU A 149MET A 211TYR A 213ASP A 214TYR A 263TRP A 349 | None | 0.43A | 3wqvA-4q6tA:33.4 | 3wqvA-4q6tA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3j | CORTICAL-LYTICENZYME (Bacillus cereus) |
PF00704(Glyco_hydro_18)PF01476(LysM) | 7 | PHE A 138ASP A 217GLU A 219MET A 281TYR A 283TYR A 324TRP A 407 | None | 0.97A | 3wqvA-4s3jA:32.2 | 3wqvA-4s3jA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3j | CORTICAL-LYTICENZYME (Bacillus cereus) |
PF00704(Glyco_hydro_18)PF01476(LysM) | 7 | PHE A 138ASP A 217MET A 281TYR A 283ASP A 284TYR A 324TRP A 407 | None | 0.89A | 3wqvA-4s3jA:32.2 | 3wqvA-4s3jA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4toq | CLASS III CHITINASE (Punica granatum) |
PF00704(Glyco_hydro_18) | 5 | PHE A 32GLY A 80ASP A 125GLU A 127TYR A 183 | None | 0.42A | 3wqvA-4toqA:19.4 | 3wqvA-4toqA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4txg | CHITINASE (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18)PF06483(ChiC) | 11 | PHE A 190GLY A 254TRP A 255ASP A 312GLU A 314MET A 395TYR A 397ASP A 398TYR A 464ARG A 466TRP A 603 | NoneNoneNoneNone CS A 803 (-2.9A) CS A 803 (-3.5A) CS A 812 (-4.4A) CS A 812 (-4.0A) CS A 812 (-4.5A)None CS A 812 ( 4.2A) | 0.46A | 3wqvA-4txgA:34.7 | 3wqvA-4txgA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uri | CHITINASE-RELATEDAGGLUTININ (Robiniapseudoacacia) |
PF00704(Glyco_hydro_18) | 7 | GLY A 73GLU A 116MET A 183TYR A 185ASP A 186TYR A 236TRP A 317 | MPD A 401 (-3.9A)MPD A 401 (-2.7A)MPD A 401 (-3.0A)MPD A 401 (-4.8A)NoneNoneMPD A 401 (-3.8A) | 0.96A | 3wqvA-4uriA:42.5 | 3wqvA-4uriA:27.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uri | CHITINASE-RELATEDAGGLUTININ (Robiniapseudoacacia) |
PF00704(Glyco_hydro_18) | 5 | PHE A 30GLY A 72ASP A 114TYR A 185TRP A 317 | NoneMPD A 401 ( 4.6A)MPD A 401 (-4.3A)MPD A 401 (-4.8A)MPD A 401 (-3.8A) | 0.95A | 3wqvA-4uriA:42.5 | 3wqvA-4uriA:27.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uri | CHITINASE-RELATEDAGGLUTININ (Robiniapseudoacacia) |
PF00704(Glyco_hydro_18) | 8 | PHE A 30GLY A 72GLU A 116MET A 183TYR A 185ASP A 186TYR A 236TRP A 317 | NoneMPD A 401 ( 4.6A)MPD A 401 (-2.7A)MPD A 401 (-3.0A)MPD A 401 (-4.8A)NoneNoneMPD A 401 (-3.8A) | 0.45A | 3wqvA-4uriA:42.5 | 3wqvA-4uriA:27.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w5u | CHITINASE (Streptomycesthermoviolaceus) |
no annotation | 11 | PHE B 78GLY B 141TRP B 142ASP B 181GLU B 183MET B 248TYR B 250ASP B 251TYR B 305ARG B 307TRP B 388 | NoneNoneMLI B 501 ( 3.8A)NoneNoneNoneNoneMLI B 501 ( 4.7A)NoneNoneNone | 0.74A | 3wqvA-4w5uB:43.8 | 3wqvA-4w5uB:29.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w5z | CHITINASE 60 (Moritellamarina) |
PF00704(Glyco_hydro_18) | 5 | PHE A 70GLY A 117ASP A 151TYR A 220TRP A 311 | NoneNoneACT A 404 (-2.7A)ACT A 404 (-4.6A)MPD A 402 ( 3.4A) | 0.64A | 3wqvA-4w5zA:21.5 | 3wqvA-4w5zA:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wiw | GLYCOSIDE HYDROLASEFAMILY 18 (Desulfitobacteriumhafniense) |
PF00704(Glyco_hydro_18) | 7 | ASP A 458GLU A 460MET A 530TYR A 532ASP A 533TYR A 574TRP A 666 | CA A 704 ( 4.4A) CA A 704 (-2.8A) CA A 704 ( 4.4A)NoneNoneNoneNone | 0.43A | 3wqvA-4wiwA:32.6 | 3wqvA-4wiwA:25.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5df0 | AC-CHIA (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 5 | PHE A 181GLY A 264ASP A 303TYR A 381TRP A 528 | 58Y A 605 (-4.5A)58Y A 605 ( 4.2A)None58Y A 605 (-4.9A)58Y A 605 (-3.7A) | 0.97A | 3wqvA-5df0A:42.2 | 3wqvA-5df0A:25.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5df0 | AC-CHIA (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 10 | PHE A 181GLY A 264TRP A 265GLU A 305MET A 379TYR A 381ASP A 382TYR A 435ARG A 437TRP A 528 | 58Y A 605 (-4.5A)58Y A 605 ( 4.2A)NAG A 603 ( 3.9A)58Y A 605 (-3.1A)58Y A 605 (-3.3A)58Y A 605 (-4.9A)58Y A 605 ( 3.0A)None58Y A 605 ( 3.3A)58Y A 605 (-3.7A) | 0.52A | 3wqvA-5df0A:42.2 | 3wqvA-5df0A:25.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gpr | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 7 | PHE A 184GLY A 267ASP A 306TYR A 383ASP A 384TYR A 437TRP A 532 | PHE A 184 ( 1.3A)GLY A 267 ( 0.0A)ASP A 306 ( 0.5A)TYR A 383 ( 1.3A)ASP A 384 ( 0.5A)TYR A 437 ( 1.3A)TRP A 532 ( 0.5A) | 0.80A | 3wqvA-5gprA:43.0 | 3wqvA-5gprA:24.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gpr | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 10 | PHE A 184GLY A 267TRP A 268GLU A 308MET A 381TYR A 383ASP A 384TYR A 437ARG A 439TRP A 532 | PHE A 184 ( 1.3A)GLY A 267 ( 0.0A)TRP A 268 ( 0.5A)GLU A 308 ( 0.6A)MET A 381 ( 0.0A)TYR A 383 ( 1.3A)ASP A 384 ( 0.5A)TYR A 437 ( 1.3A)ARG A 439 ( 0.6A)TRP A 532 ( 0.5A) | 0.44A | 3wqvA-5gprA:43.0 | 3wqvA-5gprA:24.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 8 | PHE B 590GLY B 651ASP B 689MET B 764TYR B 766ASP B 767TYR B 816TRP B 905 | None | 0.74A | 3wqvA-5gztB:43.8 | 3wqvA-5gztB:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 10 | PHE B 590GLY B 651TRP B 652GLU B 691MET B 764TYR B 766ASP B 767TYR B 816ARG B 818TRP B 905 | None | 0.52A | 3wqvA-5gztB:43.8 | 3wqvA-5gztB:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 7 | PHE B1077GLY B1137ASP B1175TYR B1252ASP B1253TYR B1304TRP B1396 | None | 0.84A | 3wqvA-5gztB:43.8 | 3wqvA-5gztB:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 9 | PHE B1077GLY B1137GLU B1177MET B1250TYR B1252ASP B1253TYR B1304ARG B1306TRP B1396 | None | 0.75A | 3wqvA-5gztB:43.8 | 3wqvA-5gztB:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 9 | PHE B1077GLY B1137TRP B1138GLU B1177MET B1250TYR B1252ASP B1253TYR B1304TRP B1396 | None | 0.76A | 3wqvA-5gztB:43.8 | 3wqvA-5gztB:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 8 | PHE A 590GLY A 651ASP A 689MET A 764TYR A 766ASP A 767TYR A 816TRP A 905 | None | 0.74A | 3wqvA-5gzuA:44.1 | 3wqvA-5gzuA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 10 | PHE A 590GLY A 651TRP A 652GLU A 691MET A 764TYR A 766ASP A 767TYR A 816ARG A 818TRP A 905 | None | 0.54A | 3wqvA-5gzuA:44.1 | 3wqvA-5gzuA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 7 | PHE A1077GLY A1137ASP A1175TYR A1252ASP A1253TYR A1304TRP A1396 | None | 0.82A | 3wqvA-5gzuA:44.1 | 3wqvA-5gzuA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 10 | PHE A1077GLY A1137TRP A1138GLU A1177MET A1250TYR A1252ASP A1253TYR A1304ARG A1306TRP A1396 | None | 0.89A | 3wqvA-5gzuA:44.1 | 3wqvA-5gzuA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jh8 | PROBABLE CHITINASE (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18) | 6 | ASP A 109GLU A 111MET A 174TYR A 176ASP A 177TYR A 217 | HIS A 505 (-2.3A)HIS A 505 (-2.8A)HIS A 505 (-3.8A)6KY A 504 (-4.0A)6KY A 504 (-2.6A)6KY A 504 (-3.1A) | 0.40A | 3wqvA-5jh8A:33.3 | 3wqvA-5jh8A:24.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvb | CHITINASE (Ostriniafurnacalis) |
no annotation | 6 | PHE A 129GLY A 175ASP A 215TYR A 285TYR A 340TRP A 433 | NAG A 505 (-4.5A)NAG A 504 (-3.7A)NAG A 504 (-3.8A)NAG A 504 (-4.5A)NAG A 505 (-4.1A)NAG A 504 (-3.6A) | 0.84A | 3wqvA-5wvbA:54.5 | 3wqvA-5wvbA:10.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvb | CHITINASE (Ostriniafurnacalis) |
no annotation | 9 | PHE A 129GLY A 175TRP A 176MET A 283TYR A 285ASP A 286TYR A 340ARG A 342TRP A 433 | NAG A 505 (-4.5A)NAG A 504 (-3.7A)NAG A 503 (-3.3A)NAG A 503 (-4.0A)NAG A 504 (-4.5A)NAG A 504 (-3.5A)NAG A 505 (-4.1A)NAG A 503 (-3.7A)NAG A 504 (-3.6A) | 0.44A | 3wqvA-5wvbA:54.5 | 3wqvA-5wvbA:10.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvg | CHITINASE (Ostriniafurnacalis) |
no annotation | 5 | PHE A 565GLY A 605ASP A 645TYR A 715TRP A 864 | NAG A1003 ( 4.8A)NAG A1003 (-3.5A)NAG A1003 (-3.9A)NAG A1003 (-4.5A)NAG A1003 (-3.4A) | 0.98A | 3wqvA-5wvgA:54.3 | 3wqvA-5wvgA:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvg | CHITINASE (Ostriniafurnacalis) |
no annotation | 9 | PHE A 565GLY A 605TRP A 606MET A 713TYR A 715ASP A 716TYR A 770ARG A 772TRP A 864 | NAG A1003 ( 4.8A)NAG A1003 (-3.5A)NAG A1004 (-3.4A)NAG A1003 (-3.6A)NAG A1003 (-4.5A)NAG A1003 (-3.1A)NAG A1002 (-4.2A)NAG A1004 (-3.1A)NAG A1003 (-3.4A) | 0.30A | 3wqvA-5wvgA:54.3 | 3wqvA-5wvgA:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xep | CHITINASE-3-LIKEPROTEIN 1 (Mus musculus) |
no annotation | 6 | PHE A 58GLY A 99MET A 205TYR A 207ASP A 208TRP A 353 | None | 0.73A | 3wqvA-5xepA:52.4 | 3wqvA-5xepA:10.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xep | CHITINASE-3-LIKEPROTEIN 1 (Mus musculus) |
no annotation | 6 | PHE A 58GLY A 99TRP A 100MET A 205ASP A 208TRP A 353 | None | 0.83A | 3wqvA-5xepA:52.4 | 3wqvA-5xepA:10.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwq | FUNGAL CHITINASEFROM RHIZOMUCORMIEHEI (NATIVEPROTEIN) (Rhizomucormiehei) |
no annotation | 5 | GLU A 182MET A 254TYR A 256ASP A 257ARG A 312 | None | 0.97A | 3wqvA-5xwqA:40.4 | 3wqvA-5xwqA:11.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwq | FUNGAL CHITINASEFROM RHIZOMUCORMIEHEI (NATIVEPROTEIN) (Rhizomucormiehei) |
no annotation | 10 | PHE A 104GLY A 141TRP A 142ASP A 180GLU A 182MET A 254TYR A 256ASP A 257TYR A 310TRP A 425 | None | 0.44A | 3wqvA-5xwqA:40.4 | 3wqvA-5xwqA:11.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y29 | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 10 | PHE A1648GLY A1690TRP A1691ASP A1731GLU A1733MET A1801TYR A1803ASP A1804TYR A1856TRP A1961 | None | 0.31A | 3wqvA-5y29A:55.2 | 3wqvA-5y29A:12.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y2a | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 10 | PHE A2094GLY A2137TRP A2138ASP A2178GLU A2180MET A2248TYR A2250ASP A2251TYR A2303TRP A2398 | None | 0.54A | 3wqvA-5y2aA:55.3 | 3wqvA-5y2aA:14.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zl9 | CHITINASE AB (Serratiamarcescens) |
no annotation | 11 | PHE A 191GLY A 274TRP A 275ASP A 313GLU A 315MET A 390TYR A 392ASP A 393TYR A 446ARG A 448TRP A 541 | GOL A 706 (-4.9A)GOL A 706 ( 4.1A)NoneGOL A 706 (-3.5A)GOL A 706 (-3.3A)GOL A 706 (-3.3A)GOL A 706 (-4.8A)GOL A 703 (-3.0A)GOL A 703 (-3.5A)GOL A 703 (-4.0A)GOL A 706 ( 3.8A) | 0.53A | 3wqvA-5zl9A:42.6 | 3wqvA-5zl9A:14.08 |