SIMILAR PATTERNS OF AMINO ACIDS FOR 3WIP_G_ACTG305_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aor ALDEHYDE FERREDOXIN
OXIDOREDUCTASE

(Pyrococcus
furiosus) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		3 ASP A 489
ARG A 444
LYS A 450
 PTE  A 609 (-3.5A)
PTE  A 609 (-3.1A)
PTE  A 609 (-2.6A)
 1.28A 3wipG-1aorA:
0.0		 3wipG-1aorA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d0n HORSE PLASMA
GELSOLIN

(Equus caballus) 		PF00626
(Gelsolin) 		3 ASP A  61
ARG A 161
LYS A 141
 None
 1.26A 3wipG-1d0nA:
undetectable		 3wipG-1d0nA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e5w MOESIN

(Homo sapiens) 		PF00373
(FERM_M)
PF09379
(FERM_N)
PF09380
(FERM_C) 		3 ASP A 266
ARG A 246
LYS A 258
 None
 1.27A 3wipG-1e5wA:
undetectable		 3wipG-1e5wA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ea6 PMS1 PROTEIN HOMOLOG
2

(Homo sapiens) 		PF01119
(DNA_mis_repair)
PF13589
(HATPase_c_3) 		3 ASP A  55
ARG A 211
LYS A  57
 None
 1.18A 3wipG-1ea6A:
0.0		 3wipG-1ea6A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fu1 DNA REPAIR PROTEIN
XRCC4

(Homo sapiens) 		PF06632
(XRCC4) 		3 ASP A 132
ARG A   3
LYS A 129
 CAS  A 128 ( 3.1A)
ACY  A 504 (-2.8A)
CAS  A 130 ( 1.3A)
 1.18A 3wipG-1fu1A:
0.0		 3wipG-1fu1A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g71 DNA PRIMASE

(Pyrococcus
furiosus) 		PF01896
(DNA_primase_S) 		3 ASP A 237
ARG A 229
LYS A 233
 None
 1.25A 3wipG-1g71A:
0.0		 3wipG-1g71A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gc7 RADIXIN

(Mus musculus) 		PF00373
(FERM_M)
PF09379
(FERM_N)
PF09380
(FERM_C) 		3 ASP A 266
ARG A 246
LYS A 258
 ASP  A 266 ( 0.6A)
ARG  A 246 ( 0.6A)
LYS  A 258 ( 0.0A)
 0.98A 3wipG-1gc7A:
0.0		 3wipG-1gc7A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itk CATALASE-PEROXIDASE

(Haloarcula
marismortui) 		PF00141
(peroxidase) 		3 ASP A 476
ARG A 416
LYS A 479
 None
 1.26A 3wipG-1itkA:
undetectable		 3wipG-1itkA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jof CARBOXY-CIS,CIS-MUCO
NATE CYCLASE

(Neurospora
crassa) 		PF10282
(Lactonase) 		3 ASP A 341
ARG A 338
LYS A 340
 None
 1.22A 3wipG-1jofA:
0.0		 3wipG-1jofA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kxv CAMELID VHH DOMAIN
CAB10

(Camelus
dromedarius) 		PF07686
(V-set) 		3 ASP C  88
ARG C  66
LYS C  86
 None
 1.09A 3wipG-1kxvC:
undetectable		 3wipG-1kxvC:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pho PHOSPHOPORIN

(Escherichia
coli) 		PF00267
(Porin_1) 		3 ASP A  12
ARG A  60
LYS A  46
 None
 1.00A 3wipG-1phoA:
undetectable		 3wipG-1phoA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rtk COMPLEMENT FACTOR B

(Homo sapiens) 		PF00089
(Trypsin)
PF00092
(VWA) 		3 ASP A 602
ARG A 714
LYS A 623
 None
 1.11A 3wipG-1rtkA:
undetectable		 3wipG-1rtkA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tol PROTEIN (FUSION
PROTEIN CONSISTING
OF MINOR COAT
PROTEIN, GLYCINE
RICH LINKER, TOLA,
AND A HIS TAG)

(Escherichia
coli;
Escherichia
virus M13) 		PF05357
(Phage_Coat_A)
PF06519
(TolA) 		3 ASP A  24
ARG A  29
LYS A  22
 None
 1.19A 3wipG-1tolA:
undetectable		 3wipG-1tolA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0q IMMUNOGLOBULIN HEAVY
CHAIN VARIABLE
DOMAIN

(Lama glama) 		PF07686
(V-set) 		3 ASP A  85
ARG A  66
LYS A  83
 None
 0.99A 3wipG-1u0qA:
undetectable		 3wipG-1u0qA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1upr PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY A MEMBER 4

(Homo sapiens) 		PF00169
(PH) 		3 ASP A1065
ARG A1075
LYS A1063
 4IP  A2154 (-3.7A)
4IP  A2154 (-3.6A)
4IP  A2154 (-2.5A)
 1.24A 3wipG-1uprA:
undetectable		 3wipG-1uprA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbk HYPOTHETICAL PROTEIN
PH1313

(Pyrococcus
horikoshii) 		PF02568
(ThiI)
PF02926
(THUMP) 		3 ASP A 253
ARG A 246
LYS A 249
 None
 1.01A 3wipG-1vbkA:
undetectable		 3wipG-1vbkA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xjv PROTECTION OF
TELOMERES 1

(Homo sapiens) 		PF02765
(POT1)
PF16686
(POT1PC) 		3 ASP A  77
ARG A 240
LYS A  74
 None
 1.21A 3wipG-1xjvA:
undetectable		 3wipG-1xjvA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e1d TRANSALDOLASE

(Mus musculus) 		PF00923
(TAL_FSA) 		3 ASP A 318
ARG A 192
LYS A 314
 None
SO3  A3016 (-4.0A)
None
 1.17A 3wipG-2e1dA:
undetectable		 3wipG-2e1dA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2een HYPOTHETICAL PROTEIN
PH1819

(Pyrococcus
horikoshii) 		PF01928
(CYTH) 		3 ASP A 125
ARG A  52
LYS A 109
 None
 1.24A 3wipG-2eenA:
undetectable		 3wipG-2eenA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gw8 PII SIGNAL
TRANSDUCTION PROTEIN

(Neisseria
meningitidis) 		PF00543
(P-II) 		3 ASP A  67
ARG A 107
LYS A   0
 None
 1.03A 3wipG-2gw8A:
undetectable		 3wipG-2gw8A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hdw HYPOTHETICAL PROTEIN
PA2218

(Pseudomonas
aeruginosa) 		PF02129
(Peptidase_S15) 		3 ASP A  84
ARG A 276
LYS A 109
 None
 1.12A 3wipG-2hdwA:
undetectable		 3wipG-2hdwA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hma PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE

(Streptococcus
pneumoniae) 		PF03054
(tRNA_Me_trans) 		3 ASP A 114
ARG A  82
LYS A 110
 None
 1.17A 3wipG-2hmaA:
undetectable		 3wipG-2hmaA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o6q VARIABLE LYMPHOCYTE
RECEPTOR A

(Eptatretus
burgeri) 		PF13855
(LRR_8) 		3 ASP A 211
ARG A 185
LYS A 209
 None
 1.04A 3wipG-2o6qA:
undetectable		 3wipG-2o6qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oaa R.MVAI

(Kocuria varians) 		PF15515
(MvaI_BcnI) 		3 ASP A  37
ARG A  25
LYS A  33
 None
 1.13A 3wipG-2oaaA:
undetectable		 3wipG-2oaaA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pce PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Roseovarius
nubinhibens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASP A  41
ARG A  82
LYS A   1
 None
 1.09A 3wipG-2pceA:
undetectable		 3wipG-2pceA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qlu ACTIVIN RECEPTOR
TYPE IIB

(Homo sapiens) 		PF00069
(Pkinase) 		3 ASP A 321
ARG A 363
LYS A 323
 None
SO4  A   2 (-2.9A)
SO4  A   2 (-3.0A)
 1.16A 3wipG-2qluA:
undetectable		 3wipG-2qluA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rad SUCCINOGLYCAN
BIOSYNTHESIS PROTEIN

(Bacillus cereus) 		PF05139
(Erythro_esteras) 		3 ASP A 230
ARG A 198
LYS A 202
 None
 1.02A 3wipG-2radA:
undetectable		 3wipG-2radA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2tmk THYMIDYLATE KINASE

(Saccharomyces
cerevisiae) 		PF02223
(Thymidylate_kin) 		3 ASP A 148
ARG A  15
LYS A 146
 None
 1.20A 3wipG-2tmkA:
undetectable		 3wipG-2tmkA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA

(Desulfovibrio
vulgaris) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		3 ASP A 233
ARG A 172
LYS A 215
 None
SO3  B 504 (-2.7A)
SRM  B 503 ( 2.4A)
 1.17A 3wipG-2v4jA:
undetectable		 3wipG-2v4jA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5p CATION-INDEPENDENT
MANNOSE-6-PHOSPHATE
RECEPTOR

(Homo sapiens) 		PF00040
(fn2)
PF00878
(CIMR) 		3 ASP A1594
ARG A1580
LYS A1593
 None
 1.03A 3wipG-2v5pA:
undetectable		 3wipG-2v5pA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x2i ALPHA-1,4-GLUCAN
LYASE ISOZYME 1

(Gracilariopsis
lemaneiformis) 		PF01055
(Glyco_hydro_31) 		3 ASP A 489
ARG A 528
LYS A 487
 None
 1.17A 3wipG-2x2iA:
undetectable		 3wipG-2x2iA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfb E1 ENVELOPE
GLYCOPROTEIN

(Chikungunya
virus) 		PF01589
(Alpha_E1_glycop) 		3 ASP A 188
ARG A 123
LYS A 176
 None
 0.87A 3wipG-2xfbA:
2.7		 3wipG-2xfbA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsj SULFITE REDUCTASE
ALPHA SUBUNIT

(Desulfomicrobium
norvegicum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		3 ASP A 233
ARG A 172
LYS A 215
 None
SO3  B 504 (-3.0A)
SRM  B 503 ( 2.6A)
 1.13A 3wipG-2xsjA:
undetectable		 3wipG-2xsjA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y2c 1,6-ANHYDRO-N-ACETYL
MURAMYL-L-ALANINE
AMIDASE AMPD

(Citrobacter
freundii) 		PF01510
(Amidase_2) 		3 ASP A 164
ARG A 161
LYS A 162
 None
 1.04A 3wipG-2y2cA:
undetectable		 3wipG-2y2cA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yoc PULLULANASE

(Klebsiella
oxytoca) 		PF02922
(CBM_48)
PF03714
(PUD)
PF11852
(DUF3372) 		3 ASP A 199
ARG A  24
LYS A 203
 None
 1.20A 3wipG-2yocA:
undetectable		 3wipG-2yocA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzm D-ALANINE--D-ALANINE
LIGASE

(Thermus
thermophilus) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		3 ASP A 183
ARG A 137
LYS A 185
 None
 1.21A 3wipG-2yzmA:
undetectable		 3wipG-2yzmA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cob KINESIN HEAVY
CHAIN-LIKE PROTEIN

(Solanum
tuberosum) 		PF00225
(Kinesin) 		3 ASP A1004
ARG A 999
LYS A1003
 None
 0.76A 3wipG-3cobA:
undetectable		 3wipG-3cobA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d2z N-ACETYLMURAMOYL-L-A
LANINE AMIDASE AMID

(Escherichia
coli) 		PF01510
(Amidase_2) 		3 ASP A 161
ARG A 158
LYS A 159
 ZN  A 262 ( 2.2A)
None
ZN  A 262 ( 4.9A)
 1.03A 3wipG-3d2zA:
undetectable		 3wipG-3d2zA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3da7 BARNASE CIRCULAR
PERMUTANT

(Bacillus
amyloliquefaciens) 		PF00545
(Ribonuclease) 		3 ASP A 100
ARG A  18
LYS A  73
 None
 1.04A 3wipG-3da7A:
undetectable		 3wipG-3da7A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwl ACTIN-RELATED
PROTEIN 2/3 COMPLEX
SUBUNIT 2

(Schizosaccharomyces
pombe) 		PF04045
(P34-Arc) 		3 ASP D 290
ARG D 283
LYS D 286
 None
 1.16A 3wipG-3dwlD:
undetectable		 3wipG-3dwlD:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzm HYPOTHETICAL
CONSERVED PROTEIN

(Thermus
thermophilus) 		no annotation 3 ASP A 153
ARG A 200
LYS A 198
 None
 0.95A 3wipG-3dzmA:
undetectable		 3wipG-3dzmA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eez PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Ruegeria
pomeroyi) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASP A  41
ARG A  82
LYS A   1
 None
 1.13A 3wipG-3eezA:
undetectable		 3wipG-3eezA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ftj MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB

(Aggregatibacter
actinomycetemcomitans) 		PF12704
(MacB_PCD) 		3 ASP A 344
ARG A 477
LYS A 341
 None
 1.06A 3wipG-3ftjA:
undetectable		 3wipG-3ftjA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2z MANNITOL-1-PHOSPHATE
5-DEHYDROGENASE

(Shigella
flexneri) 		PF01232
(Mannitol_dh)
PF08125
(Mannitol_dh_C) 		3 ASP A  22
ARG A 159
LYS A  18
 None
NA  A 391 (-3.1A)
NA  A 391 (-3.1A)
 1.25A 3wipG-3h2zA:
undetectable		 3wipG-3h2zA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i2n WD REPEAT-CONTAINING
PROTEIN 92

(Homo sapiens) 		PF00400
(WD40) 		3 ASP A  23
ARG A 266
LYS A  25
 None
 1.15A 3wipG-3i2nA:
undetectable		 3wipG-3i2nA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k44 PURINE-RICH BINDING
PROTEIN-ALPHA,
ISOFORM B

(Drosophila
melanogaster) 		PF04845
(PurA) 		3 ASP A 118
ARG A 147
LYS A 120
 EDO  A3318 (-3.1A)
None
EDO  A3318 (-4.2A)
 1.26A 3wipG-3k44A:
undetectable		 3wipG-3k44A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kpb UNCHARACTERIZED
PROTEIN MJ0100

(Methanocaldococcus
jannaschii) 		PF00571
(CBS) 		3 ASP A 426
ARG A 491
LYS A 430
 None
 0.98A 3wipG-3kpbA:
undetectable		 3wipG-3kpbA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lrk ALPHA-GALACTOSIDASE
1

(Saccharomyces
cerevisiae) 		PF16499
(Melibiase_2) 		3 ASP A 274
ARG A 400
LYS A 277
 None
 1.15A 3wipG-3lrkA:
undetectable		 3wipG-3lrkA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8o IMMUNOGLOBULIN A1
HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 ASP H  91
ARG H  69
LYS H  89
 None
 1.07A 3wipG-3m8oH:
2.6		 3wipG-3m8oH:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA

(Archaeoglobus
fulgidus) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		3 ASP A 231
ARG A 170
LYS A 213
 None
SO3  A 590 (-3.0A)
SO3  A 590 ( 2.6A)
 1.15A 3wipG-3mm5A:
undetectable		 3wipG-3mm5A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n0z ADENYLATE CYCLASE 2

(Yersinia pestis) 		PF01928
(CYTH) 		3 ASP A 126
ARG A  63
LYS A 111
 None
3AT  A 181 (-3.0A)
3AT  A 181 (-2.9A)
 1.27A 3wipG-3n0zA:
undetectable		 3wipG-3n0zA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00365
(PFK) 		3 ASP B 679
ARG B 618
LYS B 588
 None
 1.11A 3wipG-3o8oB:
undetectable		 3wipG-3o8oB:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 ASP B  91
ARG B  69
LYS B  89
 None
 0.99A 3wipG-3qo0B:
undetectable		 3wipG-3qo0B:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3thn EXONUCLEASE,
PUTATIVE

(Thermotoga
maritima) 		PF00149
(Metallophos) 		3 ASP A  39
ARG A  31
LYS A  35
 None
 0.97A 3wipG-3thnA:
undetectable		 3wipG-3thnA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqq METHIONYL-TRNA
FORMYLTRANSFERASE

(Coxiella
burnetii) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		3 ASP A  82
ARG A  27
LYS A   4
 None
 1.22A 3wipG-3tqqA:
undetectable		 3wipG-3tqqA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uo7 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE

(Homo sapiens) 		PF03167
(UDG) 		3 ASP A 202
ARG A 275
LYS A 201
 None
 0.97A 3wipG-3uo7A:
undetectable		 3wipG-3uo7A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wv4 NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Streptomyces
halstedii) 		PF00501
(AMP-binding) 		3 ASP A 230
ARG A 331
LYS A 330
 None
 1.15A 3wipG-3wv4A:
undetectable		 3wipG-3wv4A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvn NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Streptomyces
halstedii) 		PF00501
(AMP-binding) 		3 ASP A 230
ARG A 331
LYS A 330
 ASP  A 601 (-2.6A)
ASP  A 601 (-3.5A)
ASP  A 601 (-2.9A)
 1.25A 3wipG-3wvnA:
undetectable		 3wipG-3wvnA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a8j ELONGATOR COMPLEX
PROTEIN 4

(Saccharomyces
cerevisiae) 		PF05625
(PAXNEB) 		3 ASP A 242
ARG A 408
LYS A 409
 None
 1.25A 3wipG-4a8jA:
undetectable		 3wipG-4a8jA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ay2 PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58

(Homo sapiens) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF11648
(RIG-I_C-RD) 		3 ASP A 565
ARG A 559
LYS A 561
 None
 1.04A 3wipG-4ay2A:
undetectable		 3wipG-4ay2A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bj4 AMPDH2

(Pseudomonas
aeruginosa) 		PF01471
(PG_binding_1)
PF01510
(Amidase_2) 		3 ASP A 163
ARG A 160
LYS A 161
 None
 0.98A 3wipG-4bj4A:
undetectable		 3wipG-4bj4A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxj AMPDH3

(Pseudomonas
aeruginosa) 		PF01510
(Amidase_2) 		3 ASP A 156
ARG A 153
LYS A 154
 None
 0.92A 3wipG-4bxjA:
undetectable		 3wipG-4bxjA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ce5 AT-OMEGATA

(Aspergillus
terreus) 		PF01063
(Aminotran_4) 		3 ASP A 224
ARG A 266
LYS A 223
 None
 1.15A 3wipG-4ce5A:
undetectable		 3wipG-4ce5A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e0i MITOCHONDRIAL
FAD-LINKED
SULFHYDRYL OXIDASE
ERV1

(Saccharomyces
cerevisiae) 		PF04777
(Evr1_Alr) 		3 ASP A 185
ARG A 151
LYS A 184
 None
 1.21A 3wipG-4e0iA:
undetectable		 3wipG-4e0iA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9i HYDROGENASE
MATURATION PROTEIN
HYPF

(Thermococcus
kodakarensis) 		PF00708
(Acylphosphatase)
PF00814
(Peptidase_M22)
PF01300
(Sua5_yciO_yrdC)
PF07503
(zf-HYPF) 		3 ASP A 340
ARG A 365
LYS A 339
 None
 1.13A 3wipG-4g9iA:
undetectable		 3wipG-4g9iA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN

(Agrobacterium
fabrum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASP A  39
ARG A  72
LYS A   1
 None
 1.15A 3wipG-4hpnA:
undetectable		 3wipG-4hpnA:
19.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hqp ALPHA7 NICOTINIC
RECEPTOR CHIMERA

(Lymnaea
stagnalis;
Homo sapiens) 		PF02931
(Neur_chan_LBD) 		3 ASP A 131
ARG A 169
LYS A 202
 None
 1.01A 3wipG-4hqpA:
27.2		 3wipG-4hqpA:
57.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i1t RNA-DIRECTED RNA
POLYMERASE L

(Cali
mammarenavirus) 		PF17296
(ArenaCapSnatch) 		3 ASP A 118
ARG A 105
LYS A 114
 None
 1.26A 3wipG-4i1tA:
undetectable		 3wipG-4i1tA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lg9 F-BOX-LIKE/WD
REPEAT-CONTAINING
PROTEIN TBL1XR1

(Homo sapiens) 		PF00400
(WD40) 		3 ASP A 182
ARG A 513
LYS A 497
 UNX  A 616 ( 3.3A)
None
None
 1.07A 3wipG-4lg9A:
undetectable		 3wipG-4lg9A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lmx CRYPTOPHYTE
PHYCOERYTHRIN
(ALPHA-2 CHAIN)
CRYPTOPHYTE
PHYCOERYTHRIN (BETA
CHAIN)

(Hemiselmis
andersenii;
Hemiselmis
andersenii) 		PF02972
(Phycoerythr_ab)
PF00502
(Phycobilisome) 		3 ASP A   5
ARG B 108
LYS A   3
 LYZ  A   4 (-4.6A)
None
None
 0.98A 3wipG-4lmxA:
undetectable		 3wipG-4lmxA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyp EXO-BETA-1,4-MANNOSI
DASE

(Rhizomucor
miehei) 		no annotation 3 ASP A 329
ARG A 306
LYS A 328
 None
 1.21A 3wipG-4lypA:
undetectable		 3wipG-4lypA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE

(Staphylococcus
aureus) 		PF02423
(OCD_Mu_crystall) 		3 ASP A  59
ARG A  90
LYS A  83
 None
 1.17A 3wipG-4mp3A:
undetectable		 3wipG-4mp3A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n3n EUKARYOTIC
TRANSLATION
INITIATION FACTOR
5B-LIKE PROTEIN,
EIF5B(517-C)

(Chaetomium
thermophilum) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2) 		3 ASP A 892
ARG A 865
LYS A 891
 None
 1.02A 3wipG-4n3nA:
undetectable		 3wipG-4n3nA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oav PROTEIN (RNASE L)

(Homo sapiens) 		PF00069
(Pkinase)
PF06479
(Ribonuc_2-5A)
PF12796
(Ank_2)
PF13857
(Ank_5) 		3 ASP B 485
ARG B 400
LYS B 506
 MG  B 803 (-4.7A)
ACP  B 801 (-3.1A)
ACP  B 801 ( 4.8A)
 0.95A 3wipG-4oavB:
undetectable		 3wipG-4oavB:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oe5 DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00171
(Aldedh) 		3 ASP A 508
ARG A 338
LYS A 509
 None
 0.95A 3wipG-4oe5A:
undetectable		 3wipG-4oe5A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqk MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
TRUNCATED
REPLICATION PROTEIN
REPA

(Escherichia
coli;
Staphylococcus
aureus) 		PF13416
(SBP_bac_8) 		3 ASP A 441
ARG A 434
LYS A 437
 None
 1.02A 3wipG-4pqkA:
undetectable		 3wipG-4pqkA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE

(Staphylococcus
aureus) 		PF00388
(PI-PLC-X) 		3 ASP A 115
ARG A 166
LYS A 113
 None
INS  A 402 (-2.6A)
INS  A 402 (-3.9A)
 1.15A 3wipG-4rv3A:
undetectable		 3wipG-4rv3A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tpv PLATELET INHIBITOR

(Ancylostoma
caninum) 		PF00188
(CAP) 		3 ASP A 117
ARG A 159
LYS A  40
 None
 0.76A 3wipG-4tpvA:
undetectable		 3wipG-4tpvA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twl DIOSCORIN 5

(Dioscorea
japonica) 		PF00194
(Carb_anhydrase) 		3 ASP A 145
ARG A 205
LYS A 148
 None
 1.23A 3wipG-4twlA:
undetectable		 3wipG-4twlA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9v N-ALPHA-ACETYLTRANSF
ERASE 40

(Homo sapiens) 		PF00583
(Acetyltransf_1) 		3 ASP B 132
ARG B 217
LYS B 170
 None
 1.27A 3wipG-4u9vB:
undetectable		 3wipG-4u9vB:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y7d ALPHA/BETA HYDROLASE
FOLD PROTEIN

(Nakamurella
multipartita) 		PF00561
(Abhydrolase_1) 		3 ASP A 193
ARG A 288
LYS A 196
 None
 1.15A 3wipG-4y7dA:
undetectable		 3wipG-4y7dA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yji ARYL ACYLAMIDASE

(bacterium
CSBL00001) 		PF01425
(Amidase) 		3 ASP A 245
ARG A 212
LYS A 210
 None
 1.21A 3wipG-4yjiA:
undetectable		 3wipG-4yjiA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z43 FLAVIN-DEPENDENT
TRYPTOPHAN
HALOGENASE PRNA

(Pseudomonas
fluorescens) 		PF04820
(Trp_halogenase) 		3 ASP A 169
ARG A 182
LYS A 172
 None
 1.23A 3wipG-4z43A:
undetectable		 3wipG-4z43A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zgs PUTATIVE D-LACTATE
DEHYDROGENASE

(Chlamydomonas
reinhardtii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 ASP A  71
ARG A  89
LYS A  70
 None
 1.12A 3wipG-4zgsA:
undetectable		 3wipG-4zgsA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zqi D-ALANINE--D-ALANINE
LIGASE

(Yersinia pestis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		3 ASP A  44
ARG A  16
LYS A  43
 None
 1.19A 3wipG-4zqiA:
undetectable		 3wipG-4zqiA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF11974
(MG1) 		3 ASP A 411
ARG A 857
LYS A 415
 None
 1.11A 3wipG-5a42A:
undetectable		 3wipG-5a42A:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fir 5'-3'
EXORIBONUCLEASE 2
HOMOLOG

(Caenorhabditis
elegans) 		PF03159
(XRN_N) 		3 ASP A 785
ARG A 214
LYS A 215
 None
 1.10A 3wipG-5firA:
undetectable		 3wipG-5firA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5z ABC TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN

(Streptococcus
pneumoniae) 		PF01547
(SBP_bac_1) 		3 ASP A 181
ARG A 494
LYS A 239
 None
 1.23A 3wipG-5g5zA:
undetectable		 3wipG-5g5zA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gpp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD

(Escherichia
coli;
Danio rerio) 		PF02758
(PYRIN)
PF13416
(SBP_bac_8) 		3 ASP A 419
ARG A 355
LYS A 418
 None
 1.28A 3wipG-5gppA:
undetectable		 3wipG-5gppA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hy5 TRYPTOPHAN
6-HALOGENASE

(Streptomyces
toxytricini) 		PF04820
(Trp_halogenase) 		3 ASP A 307
ARG A 335
LYS A 306
 None
 1.01A 3wipG-5hy5A:
undetectable		 3wipG-5hy5A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5umx GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE

(Streptomyces
sp. CB03234) 		no annotation 3 ASP A  21
ARG A  41
LYS A  20
 None
 1.02A 3wipG-5umxA:
undetectable		 3wipG-5umxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uy3 ANTIBODY PGT144 FAB
HEAVY CHAIN

(Homo sapiens) 		no annotation 3 ASP H  33
ARG H  99
LYS H  97
 None
 1.13A 3wipG-5uy3H:
undetectable		 3wipG-5uy3H:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vu2 E1 ENVELOPE
GLYCOPROTEIN

(Chikungunya
virus) 		no annotation 3 ASP M 188
ARG M 123
LYS M 176
 None
 1.06A 3wipG-5vu2M:
3.1		 3wipG-5vu2M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x8r PROTEIN PLASTID PY

(Spinacia
oleracea) 		no annotation 3 ASP y 122
ARG y 130
LYS y 128
 None
 1.00A 3wipG-5x8ry:
undetectable		 3wipG-5x8ry:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ybv KN MOTIF AND ANKYRIN
REPEAT
DOMAIN-CONTAINING
PROTEIN 2
KINESIN-LIKE PROTEIN
KIF21A

(Homo sapiens;
Homo sapiens) 		no annotation
no annotation 		3 ASP A 771
ARG C1155
LYS C1152
 None
 1.02A 3wipG-5ybvA:
undetectable		 3wipG-5ybvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yo8 TETRAPRENYL-BETA-CUR
CUMENE SYNTHASE

(Bacillus
alcalophilus) 		no annotation 3 ASP A  85
ARG A  51
LYS A  52
 None
 1.09A 3wipG-5yo8A:
undetectable		 3wipG-5yo8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG

(Homo sapiens) 		no annotation 3 ASP H  85
ARG H  66
LYS H  83
 None
 0.91A 3wipG-6bckH:
undetectable		 3wipG-6bckH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cn1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Pseudomonas
putida) 		no annotation 3 ASP A 281
ARG A  17
LYS A 255
 None
 1.20A 3wipG-6cn1A:
undetectable		 3wipG-6cn1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dd3 CYTOSOLIC PURINE
5'-NUCLEOTIDASE

(Homo sapiens) 		no annotation 3 ASP A 429
ARG A 422
LYS A 425
 None
 1.10A 3wipG-6dd3A:
undetectable		 3wipG-6dd3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fd2 PUTATIVE APRAMYCIN
BIOSYNTHETIC
OXIDOREDUCTASE 4

(Streptoalloteichus
tenebrarius) 		no annotation 3 ASP B  58
ARG B   5
LYS B   5
 None
 1.04A 3wipG-6fd2B:
undetectable		 3wipG-6fd2B:
undetectable