SIMILAR PATTERNS OF AMINO ACIDS FOR 3WFA_A_EDTA802

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgi PROTEIN
(CHITOSANASE)

(Bacillus
circulans) 		PF01374
(Glyco_hydro_46) 		4 ASN A 132
TYR A  47
LYS A  45
ARG A 137
 None
 1.48A 3wfaA-1qgiA:
0.0
3wfaB-1qgiA:
0.0		 3wfaA-1qgiA:
18.23
3wfaB-1qgiA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v4g GLUTAMATE--CYSTEINE
LIGASE

(Escherichia
coli) 		PF04262
(Glu_cys_ligase) 		4 ASN A 289
TYR A 274
TYR A 131
ARG A 138
 None
 1.47A 3wfaA-1v4gA:
0.0
3wfaB-1v4gA:
0.0		 3wfaA-1v4gA:
21.27
3wfaB-1v4gA:
21.27