SIMILAR PATTERNS OF AMINO ACIDS FOR 3WEO_A_ACRA1001

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1dot	DUCK OVOTRANSFERRIN (Anas platyrhynchos)	PF00405 (Transferrin)	5	ALA A  94 ILE A 138 TRP A 125 PHE A 207 HIS A 116	None	1.25A	3weoA-1dotA: undetectable	3weoA-1dotA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1gny	XYLANASE 10C (Cellvibrio japonicus)	PF03426 (CBM_15)	5	ALA A 240 ASN A  92 ASP A 205 ASP A 207 ASP A 146	None	1.19A	3weoA-1gnyA: undetectable	3weoA-1gnyA: 9.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1gvc	OVOTRANSFERRIN (Anas platyrhynchos)	PF00405 (Transferrin)	5	ALA A  97 ILE A 141 TRP A 128 PHE A 210 HIS A 119	None	1.25A	3weoA-1gvcA: undetectable	3weoA-1gvcA: 11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1qlb	FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT FUMARATE REDUCTASE IRON-SULFUR PROTEIN (Wolinella succinogenes)	PF00890 (FAD_binding_2) PF02910 (Succ_DH_flav_C) PF13085 (Fer2_3) PF13183 (Fer4_8)	5	ASP B 149 ALA A 163 ILE B 137 ASP B 185 ARG B 181	None	1.47A	3weoA-1qlbB: undetectable	3weoA-1qlbB: 13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1t0a	2C-METHYL-D-ERYTHRIT OL 2,4-CYCLODIPHOSPHATE SYNTHASE (Shewanella oneidensis)	PF02542 (YgbB)	5	ALA A 120 ASP A  40 ILE A  21 ASP A  74 ASP A 121	None	1.40A	3weoA-1t0aA: undetectable	3weoA-1t0aA: 9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1t3q	QUINOLINE 2-OXIDOREDUCTASE LARGE SUBUNIT (Pseudomonas putida)	PF01315 (Ald_Xan_dh_C) PF02738 (Ald_Xan_dh_C2)	5	ASP B 159 ALA B 157 ASN B 164 ILE B  57 ARG B 110	SO4  B3105 ( 4.8A) None None None SO4  B3105 (-2.9A)	1.44A	3weoA-1t3qB: undetectable	3weoA-1t3qB: 22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1vkz	PHOSPHORIBOSYLAMINE- -GLYCINE LIGASE (Thermotoga maritima)	PF01071 (GARS_A) PF02843 (GARS_C) PF02844 (GARS_N)	5	ASP A 280 ALA A 347 ASN A  35 ILE A 398 ARG A 362	None	1.22A	3weoA-1vkzA: undetectable	3weoA-1vkzA: 17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1xc6	BETA-GALACTOSIDASE (Penicillium sp.)	PF01301 (Glyco_hydro_35) PF10435 (BetaGal_dom2) PF13363 (BetaGal_dom3) PF13364 (BetaGal_dom4_5)	5	ALA A 622 PHE A 624 ILE A 369 ASP A  80 ASP A 623	None	1.36A	3weoA-1xc6A: 7.0	3weoA-1xc6A: 22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1xso	COPPER,ZINC SUPEROXIDE DISMUTASE (Xenopus laevis)	PF00080 (Sod_Cu)	5	ASP A  99 PHE A  62 ASP A 122 ARG A  77 HIS A  69	None None None None ZN  A 152 ( 3.1A)	1.41A	3weoA-1xsoA: 2.4	3weoA-1xsoA: 9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2anp	LEUCYL AMINOPEPTIDASE (Vibrio proteolyticus)	PF04389 (Peptidase_M28)	5	ALA A 231 ASN A 235 ASP A 117 ILE A 255 HIS A  97	None None ZN  A 501 ( 2.4A) None ZN  A 502 (-3.3A)	1.47A	3weoA-2anpA: undetectable	3weoA-2anpA: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2cun	PHOSPHOGLYCERATE KINASE (Pyrococcus horikoshii)	PF00162 (PGK)	5	ALA A 148 ASN A 146 ASP A  65 ASP A  19 HIS A 360	None None None GOL  A 501 (-2.6A) 3PG  A 503 (-4.0A)	1.43A	3weoA-2cunA: undetectable	3weoA-2cunA: 17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2cun	PHOSPHOGLYCERATE KINASE (Pyrococcus horikoshii)	PF00162 (PGK)	5	ALA A 148 ASN A 146 ILE A  29 ASP A  19 HIS A 360	None None None GOL  A 501 (-2.6A) 3PG  A 503 (-4.0A)	1.14A	3weoA-2cunA: undetectable	3weoA-2cunA: 17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2d4y	FLAGELLAR HOOK-ASSOCIATED PROTEIN 1 (Salmonella enterica)	no annotation	5	ALA A 250 ASN A 337 ASP A 154 ASP A 291 ASP A 251	None	1.21A	3weoA-2d4yA: undetectable	3weoA-2d4yA: 18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2g3n	ALPHA-GLUCOSIDASE (Sulfolobus solfataricus)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	6	ALA A  88 ASP A 212 ILE A 213 TRP A 318 ASP A 320 ARG A 400	None None None None None BOG  A2000 (-3.1A)	1.12A	3weoA-2g3nA: 37.4	3weoA-2g3nA: 26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2g3n	ALPHA-GLUCOSIDASE (Sulfolobus solfataricus)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	5	ALA A  90 ASP A 212 ILE A 213 PHE A 449 HIS A 480	None	0.66A	3weoA-2g3nA: 37.4	3weoA-2g3nA: 26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2g3n	ALPHA-GLUCOSIDASE (Sulfolobus solfataricus)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	9	ASP A  87 ASP A 212 ILE A 213 TRP A 318 ASP A 320 ARG A 400 ASP A 416 PHE A 449 HIS A 480	BOG  A2000 (-2.7A) None None None None BOG  A2000 (-3.1A) BOG  A2000 (-3.0A) None None	0.29A	3weoA-2g3nA: 37.4	3weoA-2g3nA: 26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2g3n	ALPHA-GLUCOSIDASE (Sulfolobus solfataricus)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	6	ASP A  87 ASP A 212 ILE A 249 ASP A 416 PHE A 449 HIS A 480	BOG  A2000 (-2.7A) None None BOG  A2000 (-3.0A) None None	1.44A	3weoA-2g3nA: 37.4	3weoA-2g3nA: 26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2g3n	ALPHA-GLUCOSIDASE (Sulfolobus solfataricus)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	5	ASP A 416 ASP A  87 ARG A 400 ASP A 320 HIS A 252	BOG  A2000 (-3.0A) BOG  A2000 (-2.7A) BOG  A2000 (-3.1A) None None	1.32A	3weoA-2g3nA: 37.4	3weoA-2g3nA: 26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2qk4	TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 (Homo sapiens)	PF01071 (GARS_A) PF02843 (GARS_C) PF02844 (GARS_N)	5	ASP A 295 ALA A 370 ASN A  36 ILE A 421 ARG A 385	None None None None GOL  A 804 (-4.2A)	1.22A	3weoA-2qk4A: undetectable	3weoA-2qk4A: 18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2x2i	ALPHA-1,4-GLUCAN LYASE ISOZYME 1 (Gracilariopsis lemaneiformis)	PF01055 (Glyco_hydro_31)	8	ASP A 239 ASN A 244 ASP A 412 ASP A 553 ARG A 649 ASP A 665 PHE A 698 HIS A 731	QPS  A1050 (-2.5A) None QPS  A1050 (-3.2A) QPS  A1050 (-3.1A) QPS  A1050 (-3.2A) QPS  A1050 (-2.7A) QPS  A1050 (-4.3A) QPS  A1050 (-4.3A)	0.70A	3weoA-2x2iA: 34.9	3weoA-2x2iA: 24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2x2i	ALPHA-1,4-GLUCAN LYASE ISOZYME 1 (Gracilariopsis lemaneiformis)	PF01055 (Glyco_hydro_31)	8	ASP A 239 ASP A 412 TRP A 551 ASP A 553 ARG A 649 ASP A 665 PHE A 698 HIS A 731	QPS  A1050 (-2.5A) QPS  A1050 (-3.2A) QPS  A1050 (-4.8A) QPS  A1050 (-3.1A) QPS  A1050 (-3.2A) QPS  A1050 (-2.7A) QPS  A1050 (-4.3A) QPS  A1050 (-4.3A)	0.57A	3weoA-2x2iA: 34.9	3weoA-2x2iA: 24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2xr1	CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 100 KD SUBUNIT (Methanosarcina mazei)	PF07521 (RMMBL) PF07650 (KH_2) PF10996 (Beta-Casp) PF16661 (Lactamase_B_6) PF17214 (KH_7)	5	ALA A 327 ASN A 326 ASP A 246 ASP A 209 HIS A 604	None None ZN  A1639 (-2.7A) None ZN  A1639 (-3.3A)	1.34A	3weoA-2xr1A: undetectable	3weoA-2xr1A: 22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2xvg	ALPHA XYLOSIDASE (Cellvibrio japonicus)	PF01055 (Glyco_hydro_31) PF16338 (DUF4968) PF17137 (DUF5110)	7	ASP A 470 TRP A 580 ASP A 582 ARG A 642 ASP A 659 PHE A 692 HIS A 740	None	0.43A	3weoA-2xvgA: 42.2	3weoA-2xvgA: 25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ybx	PHOSPHATIDYLINOSITOL -5-PHOSPHATE 4-KINASE TYPE-2 ALPHA (Homo sapiens)	PF01504 (PIP5K)	5	ASP A 211 ILE A 404 ASP A 235 ARG A 219 PHE A 397	PHD  A 359 ( 3.1A) None None PO4  A1406 (-3.7A) None	1.23A	3weoA-2ybxA: undetectable	3weoA-2ybxA: 17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2yky	BETA-TRANSAMINASE (Mesorhizobium sp. LUK)	PF00202 (Aminotran_3)	5	ASP A 169 ALA A 180 ASN A 178 ARG A 388 HIS A 375	None	1.50A	3weoA-2ykyA: 2.8	3weoA-2ykyA: 19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ys6	PHOSPHORIBOSYLGLYCIN AMIDE SYNTHETASE (Geobacillus kaustophilus)	PF01071 (GARS_A) PF02843 (GARS_C) PF02844 (GARS_N)	5	ASP A 290 ALA A 361 ASN A  34 ILE A 412 ARG A 376	None	1.23A	3weoA-2ys6A: undetectable	3weoA-2ys6A: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2yw2	PHOSPHORIBOSYLAMINE- -GLYCINE LIGASE (Aquifex aeolicus)	PF01071 (GARS_A) PF02843 (GARS_C) PF02844 (GARS_N)	5	ASP A 290 ALA A 363 ASN A  34 ILE A 414 ARG A 378	None None None None PO4  A 645 (-3.6A)	1.27A	3weoA-2yw2A: undetectable	3weoA-2yw2A: 18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3af5	PUTATIVE UNCHARACTERIZED PROTEIN PH1404 (Pyrococcus horikoshii)	PF07521 (RMMBL) PF10996 (Beta-Casp) PF16661 (Lactamase_B_6) PF17214 (KH_7)	5	ALA A 342 ASN A 341 ASP A 260 ASP A 217 HIS A 618	None ACY  A 658 (-3.4A) ZN  A 665 ( 2.9A) None ZN  A 665 ( 3.3A)	1.31A	3weoA-3af5A: undetectable	3weoA-3af5A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ce1	SUPEROXIDE DISMUTASE [CU-ZN] (Naganishia liquefaciens)	PF00080 (Sod_Cu)	5	ASP A 105 PHE A  68 ASP A 128 ARG A  83 HIS A  75	None None None None ZN  A 202 (-3.1A)	1.43A	3weoA-3ce1A: undetectable	3weoA-3ce1A: 10.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ctt	MALTASE-GLUCOAMYLASE (Homo sapiens)	PF00088 (Trefoil) PF01055 (Glyco_hydro_31) PF16863 (NtCtMGAM_N)	10	ASP A 203 ASN A 207 ASP A 327 ILE A 328 TRP A 441 ASP A 443 ARG A 526 ASP A 542 PHE A 575 HIS A 600	GOL  A3001 (-2.6A) None 3CU  A1001 (-2.7A) 3CU  A1001 ( 3.9A) 3CU  A1001 (-4.9A) 3CU  A1001 (-2.7A) 3CU  A1001 ( 3.5A) 3CU  A1001 ( 2.5A) 3CU  A1001 (-4.5A) 3CU  A1001 (-3.9A)	0.71A	3weoA-3cttA: 55.0	3weoA-3cttA: 36.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3enq	RIBOSE-5-PHOSPHATE ISOMERASE A (Vibrio vulnificus)	PF06026 (Rib_5-P_isom_A)	5	ALA A  83 ASP A 170 ILE A 168 ASP A  84 PHE A 129	None	1.50A	3weoA-3enqA: undetectable	3weoA-3enqA: 13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3fnb	ACYLAMINOACYL PEPTIDASE SMU_737 (Streptococcus mutans)	PF12146 (Hydrolase_4)	5	ASN A  63 ASP A 191 ASP A 171 ARG A  97 PHE A 114	None	1.22A	3weoA-3fnbA: undetectable	3weoA-3fnbA: 17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3gz8	MUTT/NUDIX FAMILY PROTEIN (Shewanella oneidensis)	PF00293 (NUDIX)	5	ALA A  97 ASP A  23 ASP A  96 PHE A 140 HIS A 142	None APR  A 302 (-2.9A) APR  A 302 (-3.6A) APR  A 302 (-3.6A) APR  A 302 (-4.0A)	1.45A	3weoA-3gz8A: undetectable	3weoA-3gz8A: 11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ikf	2-C-METHYL-D-ERYTHRI TOL 2,4-CYCLODIPHOSPHATE SYNTHASE (Burkholderia pseudomallei)	PF02542 (YgbB)	5	ALA A 120 ASP A  40 ILE A  21 ASP A  74 ASP A 121	None	1.39A	3weoA-3ikfA: undetectable	3weoA-3ikfA: 11.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3lpp	SUCRASE-ISOMALTASE (Homo sapiens)	PF00088 (Trefoil) PF01055 (Glyco_hydro_31) PF16863 (NtCtMGAM_N)	9	ASP A 231 ASP A 355 ILE A 356 TRP A 470 ASP A 472 ARG A 555 ASP A 571 PHE A 604 HIS A 629	None TRS  A6001 (-2.9A) TRS  A6001 ( 4.0A) None TRS  A6001 (-3.2A) TRS  A6001 ( 4.6A) TRS  A6001 ( 3.7A) TRS  A6001 (-4.4A) TRS  A6001 (-4.2A)	0.29A	3weoA-3lppA: 49.2	3weoA-3lppA: 35.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3lpp	SUCRASE-ISOMALTASE (Homo sapiens)	PF00088 (Trefoil) PF01055 (Glyco_hydro_31) PF16863 (NtCtMGAM_N)	6	ASP A 231 ASP A 355 ILE A 392 ASP A 571 PHE A 604 HIS A 629	None TRS  A6001 (-2.9A) None TRS  A6001 ( 3.7A) TRS  A6001 (-4.4A) TRS  A6001 (-4.2A)	1.44A	3weoA-3lppA: 49.2	3weoA-3lppA: 35.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3mjf	PHOSPHORIBOSYLAMINE- -GLYCINE LIGASE (Yersinia pestis)	PF01071 (GARS_A) PF02843 (GARS_C) PF02844 (GARS_N)	5	ASP A 293 ALA A 367 ASN A  34 ILE A 419 ARG A 383	None None None None SO4  A 508 (-3.9A)	1.25A	3weoA-3mjfA: undetectable	3weoA-3mjfA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ogr	BETA-GALACTOSIDASE (Trichoderma reesei)	PF01301 (Glyco_hydro_35) PF10435 (BetaGal_dom2) PF13363 (BetaGal_dom3) PF13364 (BetaGal_dom4_5)	5	ALA A 624 PHE A 626 ILE A 368 ASP A  80 ASP A 625	None	1.30A	3weoA-3ogrA: 7.6	3weoA-3ogrA: 23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3om5	LEVANSUCRASE (Bacillus megaterium)	PF02435 (Glyco_hydro_68)	5	ASP A  90 ALA A  79 PHE A 133 ASN A 147 ASP A 448	None	1.46A	3weoA-3om5A: undetectable	3weoA-3om5A: 18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3poc	ALPHA-GLUCOSIDASE (Blautia obeum)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	5	ALA A 448 ASN A 431 ASP A 197 ILE A 234 ASP A 449	None None ACR  A 664 (-2.9A) None None	1.32A	3weoA-3pocA: 42.2	3weoA-3pocA: 26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3poc	ALPHA-GLUCOSIDASE (Blautia obeum)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	7	ASP A  73 ASP A 197 ILE A 198 ARG A 404 ASP A 420 PHE A 453 HIS A 478	None ACR  A 664 (-2.9A) ACR  A 664 (-3.5A) ACR  A 664 (-4.0A) ACR  A 664 (-2.8A) ACR  A 664 (-4.4A) ACR  A 664 (-4.2A)	0.33A	3weoA-3pocA: 42.2	3weoA-3pocA: 26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3poc	ALPHA-GLUCOSIDASE (Blautia obeum)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	5	ASP A 197 ILE A 198 TRP A 305 PHE A 453 HIS A 478	ACR  A 664 (-2.9A) ACR  A 664 (-3.5A) None ACR  A 664 (-4.4A) ACR  A 664 (-4.2A)	0.75A	3weoA-3pocA: 42.2	3weoA-3pocA: 26.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3top	MALTASE-GLUCOAMYLASE , INTESTINAL (Homo sapiens)	PF00088 (Trefoil) PF01055 (Glyco_hydro_31) PF16863 (NtCtMGAM_N)	9	ASP A1157 ASP A1279 ILE A1280 TRP A1418 ASP A1420 ARG A1510 ASP A1526 PHE A1559 HIS A1584	ACR  A   1 (-2.6A) ACR  A   1 (-3.2A) ACR  A   1 (-4.1A) None ACR  A   1 (-3.6A) ACR  A   1 (-2.9A) ACR  A   1 (-2.8A) ACR  A   1 (-4.3A) ACR  A   1 (-3.9A)	0.38A	3weoA-3topA: 45.0	3weoA-3topA: 34.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ugk	SACCHAROPINE DEHYDROGENASE [NAD+, L-LYSINE-FORMING] (Saccharomyces cerevisiae)	PF05222 (AlaDh_PNT_N)	5	ALA A 165 ASN A 299 ASP A 182 ARG A 149 HIS A 157	None	1.12A	3weoA-3ugkA: undetectable	3weoA-3ugkA: 18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3wc3	ENDO-1, 4-BETA-GLUCANASE (Eisenia fetida)	PF00759 (Glyco_hydro_9)	5	ASP A  60 ALA A 159 ASN A  63 ASP A  77 ARG A 157	None	1.49A	3weoA-3wc3A: undetectable	3weoA-3wc3A: 19.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3wel	ALPHA-GLUCOSIDASE (Beta vulgaris)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2) PF16863 (NtCtMGAM_N)	12	ASP A 232 ALA A 234 PHE A 236 ASN A 237 ASP A 357 ILE A 358 TRP A 467 ASP A 469 ARG A 552 ASP A 568 PHE A 601 HIS A 626	ACR  A1001 (-2.7A) ACR  A1001 (-3.7A) ACR  A1001 (-4.9A) ACR  A1001 (-3.0A) ACR  A1001 (-3.0A) ACR  A1001 (-3.6A) None ACR  A1001 (-3.2A) ACR  A1001 (-3.0A) ACR  A1001 (-2.7A) ACR  A1001 (-4.3A) ACR  A1001 (-4.1A)	0.06A	3weoA-3welA: 62.1	3weoA-3welA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3wel	ALPHA-GLUCOSIDASE (Beta vulgaris)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2) PF16863 (NtCtMGAM_N)	9	ASP A 232 ALA A 234 PHE A 236 ASN A 237 ASP A 357 ILE A 396 ASP A 568 PHE A 601 HIS A 626	ACR  A1001 (-2.7A) ACR  A1001 (-3.7A) ACR  A1001 (-4.9A) ACR  A1001 (-3.0A) ACR  A1001 (-3.0A) ACR  A1001 (-4.9A) ACR  A1001 (-2.7A) ACR  A1001 (-4.3A) ACR  A1001 (-4.1A)	1.38A	3weoA-3welA: 62.1	3weoA-3welA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ayg	GLUCANSUCRASE (Lactobacillus reuteri)	PF01473 (CW_binding_1) PF02324 (Glyco_hydro_70)	5	ASP A 934 ALA A1737 PHE A1753 ASP A1767 ASP A1754	None	1.09A	3weoA-4aygA: 3.6	3weoA-4aygA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4b9y	ALPHA-GLUCOSIDASE, PUTATIVE, ADG31B (Cellvibrio japonicus)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2) PF16338 (DUF4968) PF17137 (DUF5110)	5	ASP A 299 ILE A 341 ASP A 480 PHE A 513 HIS A 540	None	1.37A	3weoA-4b9yA: 37.8	3weoA-4b9yA: 25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4b9y	ALPHA-GLUCOSIDASE, PUTATIVE, ADG31B (Cellvibrio japonicus)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2) PF16338 (DUF4968) PF17137 (DUF5110)	7	ASP A 299 TRP A 410 ASP A 412 ARG A 463 ASP A 480 PHE A 513 HIS A 540	None	0.39A	3weoA-4b9yA: 37.8	3weoA-4b9yA: 25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4bn5	NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL (Homo sapiens)	PF02146 (SIR2)	5	PHE A 294 ILE A 154 ASP A 156 ARG A 158 PHE A 180	SR7  A1396 (-3.5A) CNA  A1395 (-3.8A) SR7  A1396 ( 3.6A) CNA  A1395 ( 3.6A) SR7  A1396 (-3.7A)	1.31A	3weoA-4bn5A: undetectable	3weoA-4bn5A: 15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4di5	5-EPI-ARISTOLOCHENE SYNTHASE (Nicotiana tabacum)	PF01397 (Terpene_synth) PF03936 (Terpene_synth_C)	5	ASP A 444 ALA A 447 ASN A 523 ASP A 302 ASP A 525	DPO  A 605 (-2.6A) None None None DPO  A 605 ( 4.6A)	1.40A	3weoA-4di5A: undetectable	3weoA-4di5A: 20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4iug	BETA-GALACTOSIDASE A (Aspergillus oryzae)	PF01301 (Glyco_hydro_35) PF10435 (BetaGal_dom2) PF13363 (BetaGal_dom3) PF13364 (BetaGal_dom4_5)	5	ALA A 619 PHE A 621 ILE A 368 ASP A  80 ASP A 620	None	1.35A	3weoA-4iugA: 5.7	3weoA-4iugA: 22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4nen	INTEGRIN ALPHA-X INTEGRIN BETA-2 (Homo sapiens)	PF00092 (VWA) PF00362 (Integrin_beta) PF01839 (FG-GAP) PF07965 (Integrin_B_tail) PF08441 (Integrin_alpha2) PF17205 (PSI_integrin)	5	ASP A 663 PHE A 608 ILE B 482 ASP A 706 ARG A 670	None	1.25A	3weoA-4nenA: 2.5	3weoA-4nenA: 23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4oet	PUTATIVE PEPTIDE ABC-TRANSPORT SYSTEM PERIPLASMIC PEPTIDE-BINDING PROTEIN (Campylobacter jejuni)	PF00496 (SBP_bac_5)	5	PHE A 380 ASP A  25 ASP A 240 ARG A 242 HIS A 393	None	1.50A	3weoA-4oetA: undetectable	3weoA-4oetA: 18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4qpm	MITOTIC CHECKPOINT SERINE/THREONINE-PRO TEIN KINASE BUB1 (Homo sapiens)	PF00069 (Pkinase)	5	ALA A 993 PHE A 989 ASP A 946 ASP A 921 HIS A 915	None None MG  A1503 (-1.7A) None None	1.47A	3weoA-4qpmA: undetectable	3weoA-4qpmA: 17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4rvp	SUPEROXIDE DISMUTASE (Sedum alfredii)	PF00080 (Sod_Cu)	5	ASP A 113 PHE A  76 ASP A 136 ARG A  91 HIS A  83	None None None None ZN  A 201 (-3.1A)	1.46A	3weoA-4rvpA: undetectable	3weoA-4rvpA: 10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4rxu	PERIPLASMIC SUGAR-BINDING PROTEIN (Chloroflexus aurantiacus)	PF13407 (Peripla_BP_4)	5	ASP A 138 PHE A  72 ASP A 298 ARG A  64 ASP A  68	BGC  A 402 (-3.0A) None BGC  A 402 (-2.7A) BGC  A 402 (-3.9A) None	1.46A	3weoA-4rxuA: undetectable	3weoA-4rxuA: 17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4u10	POLY-BETA-1,6-N-ACET YL-D-GLUCOSAMINE N-DEACETYLASE (Aggregatibacter actinomycetemcomitans)	PF01522 (Polysacc_deac_1)	5	ALA A 255 PHE A 237 ILE A 264 TRP A  75 HIS A 252	None	1.39A	3weoA-4u10A: 3.7	3weoA-4u10A: 14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4wqe	THIOSULFATE DEHYDROGENASE (Allochromatium vinosum)	PF13442 (Cytochrome_CBB3)	5	ALA A 174 ASP A  34 ARG A 177 ASP A 173 HIS A  51	None None None None HEC  A1002 (-4.9A)	1.46A	3weoA-4wqeA: undetectable	3weoA-4wqeA: 15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4x81	MYCINAMICIN III 3''-O-METHYLTRANSFER ASE (Micromonospora griseorubida)	PF05711 (TylF)	5	ASP A 244 ASP A 191 ILE A 220 ASP A 216 ARG A  61	None MVI  A 305 ( 2.7A) MVI  A 305 ( 4.3A) MG  A 304 ( 2.9A) MVI  A 305 ( 4.3A)	1.47A	3weoA-4x81A: undetectable	3weoA-4x81A: 15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4xeq	TRAP DICARBOXYLATE TRANSPORTER, DCTP SUBUNIT (Desulfovibrio vulgaris)	PF03480 (DctP)	5	ASP A 133 ALA A 128 PHE A 122 ILE A 100 ARG A 279	None	1.20A	3weoA-4xeqA: undetectable	3weoA-4xeqA: 16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ypv	EST8 (Parvibaculum)	PF07859 (Abhydrolase_3)	5	ALA A 290 ASP A 158 ILE A 186 ASP A  42 HIS A  97	None	1.44A	3weoA-4ypvA: undetectable	3weoA-4ypvA: 14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4z11	AURONE SYNTHASE (Coreopsis grandiflora)	PF00264 (Tyrosinase) PF12142 (PPO1_DWL) PF12143 (PPO1_KFDV)	5	ASP A 429 PHE A 425 ILE A 198 ARG A 496 ASP A 192	None	1.20A	3weoA-4z11A: undetectable	3weoA-4z11A: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4zg8	ENDOGLUCANASE (Perinereis brevicirris)	PF00759 (Glyco_hydro_9)	5	ASP A  47 ALA A 144 ASN A  50 ASP A  64 ARG A 142	None	1.50A	3weoA-4zg8A: undetectable	3weoA-4zg8A: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5cdc	VP1, STRUCTURAL POLYPROTEIN (Israeli acute paralysis virus)	PF08762 (CRPV_capsid)	5	ASP A  76 ALA A 183 ILE A 156 ASP A  71 PHE A 188	None	1.44A	3weoA-5cdcA: undetectable	3weoA-5cdcA: 13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5djw	ALPHA-GLUCOSIDASE II (Bacteroides thetaiotaomicron)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2) PF17137 (DUF5110)	5	ASP A 211 ASP A 321 ARG A 385 ASP A 401 PHE A 434	None	1.45A	3weoA-5djwA: 38.5	3weoA-5djwA: 28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5djw	ALPHA-GLUCOSIDASE II (Bacteroides thetaiotaomicron)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2) PF17137 (DUF5110)	5	ASP A 211 TRP A 319 ASP A 321 ASP A 401 PHE A 434	None	1.46A	3weoA-5djwA: 38.5	3weoA-5djwA: 28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5dkx	ALPHA GLUCOSIDASE-LIKE PROTEIN (Chaetomium thermophilum)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2) PF17137 (DUF5110)	9	ASP A 303 ASP A 443 ILE A 444 TRP A 554 ASP A 556 ARG A 617 ASP A 633 PHE A 666 HIS A 691	None TRS  A1001 (-2.9A) TRS  A1001 ( 4.1A) TRS  A1001 (-4.9A) TRS  A1001 (-3.2A) TRS  A1001 (-4.0A) TRS  A1001 (-2.8A) TRS  A1001 (-4.5A) TRS  A1001 (-4.0A)	0.31A	3weoA-5dkxA: 38.8	3weoA-5dkxA: 27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5dkx	ALPHA GLUCOSIDASE-LIKE PROTEIN (Chaetomium thermophilum)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2) PF17137 (DUF5110)	7	ASP A 303 ASP A 443 ILE A 480 ARG A 617 ASP A 633 PHE A 666 HIS A 691	None TRS  A1001 (-2.9A) None TRS  A1001 (-4.0A) TRS  A1001 (-2.8A) TRS  A1001 (-4.5A) TRS  A1001 (-4.0A)	1.36A	3weoA-5dkxA: 38.8	3weoA-5dkxA: 27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5dkx	ALPHA GLUCOSIDASE-LIKE PROTEIN (Chaetomium thermophilum)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2) PF17137 (DUF5110)	5	ASP A 303 TRP A 415 ASP A 633 PHE A 667 HIS A 693	None None TRS  A1001 (-2.8A) None None	1.42A	3weoA-5dkxA: 38.8	3weoA-5dkxA: 27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5f7c	ALPHA-GLUCOSIDASE (Bacteroides thetaiotaomicron)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	5	ASN A 233 ASP A 348 ASP A 523 PHE A 556 HIS A 588	None	1.47A	3weoA-5f7cA: 29.8	3weoA-5f7cA: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5f7c	ALPHA-GLUCOSIDASE (Bacteroides thetaiotaomicron)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	6	ASP A 228 ASN A 234 ASP A 348 ASP A 460 ARG A 507 PHE A 556	None	0.99A	3weoA-5f7cA: 29.8	3weoA-5f7cA: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5f7c	ALPHA-GLUCOSIDASE (Bacteroides thetaiotaomicron)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	7	ASP A 228 ASP A 348 ASP A 460 ARG A 507 ASP A 523 PHE A 556 HIS A 588	None	0.46A	3weoA-5f7cA: 29.8	3weoA-5f7cA: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5f7s	GLYCOSIDE HYDROLASE FAMILY 31 (Trueperella pyogenes)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	5	ASP A 467 ARG A 516 ASP A 532 PHE A 565 HIS A 591	CA  A 805 (-2.9A) CA  A 805 ( 4.6A) CA  A 805 ( 4.6A) None None	0.52A	3weoA-5f7sA: 36.4	3weoA-5f7sA: 21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5hjr	NEUTRAL ALPHA-GLUCOSIDASE AB (Mus musculus)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	9	ASP A 305 ASP A 451 ILE A 452 TRP A 562 ASP A 564 ARG A 624 ASP A 640 PHE A 673 HIS A 698	None 5GF  A1021 (-2.0A) 5GF  A1021 (-3.6A) 5GF  A1021 (-4.6A) 5GF  A1021 (-2.1A) 5GF  A1021 (-3.4A) 5GF  A1021 (-2.6A) 5GF  A1021 (-3.6A) 5GF  A1021 (-4.0A)	0.26A	3weoA-5hjrA: 50.2	3weoA-5hjrA: 29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5hjr	NEUTRAL ALPHA-GLUCOSIDASE AB (Mus musculus)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	7	ASP A 305 ASP A 451 ILE A 488 ARG A 624 ASP A 640 PHE A 673 HIS A 698	None 5GF  A1021 (-2.0A) None 5GF  A1021 (-3.4A) 5GF  A1021 (-2.6A) 5GF  A1021 (-3.6A) 5GF  A1021 (-4.0A)	1.30A	3weoA-5hjrA: 50.2	3weoA-5hjrA: 29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ip9	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (Saccharomyces cerevisiae)	PF00562 (RNA_pol_Rpb2_6) PF04560 (RNA_pol_Rpb2_7) PF04561 (RNA_pol_Rpb2_2) PF04563 (RNA_pol_Rpb2_1) PF04565 (RNA_pol_Rpb2_3) PF04566 (RNA_pol_Rpb2_4) PF04567 (RNA_pol_Rpb2_5)	5	ALA B 793 ASN B 794 ILE B 204 ARG B 788 ASP B 790	None	1.46A	3weoA-5ip9B: undetectable	3weoA-5ip9B: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5jd3	LAE5 (uncultured bacterium)	PF13472 (Lipase_GDSL_2)	5	ALA A 150 ASP A 172 ASP A 178 ARG A 144 ASP A 153	SO4  A 303 (-3.2A) None None None None	1.47A	3weoA-5jd3A: 2.3	3weoA-5jd3A: 13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5jou	ALPHA-XYLOSIDASE BOGH31A (Bacteroides ovatus)	PF01055 (Glyco_hydro_31) PF16338 (DUF4968) PF17137 (DUF5110)	6	ASN A 319 ASP A 441 TRP A 551 ASP A 553 ARG A 613 HIS A 709	None EDO  A1008 (-2.8A) None EDO  A1008 (-2.7A) EDO  A1008 (-4.6A) EDO  A1008 (-4.0A)	1.08A	3weoA-5jouA: 36.7	3weoA-5jouA: 25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5jou	ALPHA-XYLOSIDASE BOGH31A (Bacteroides ovatus)	PF01055 (Glyco_hydro_31) PF16338 (DUF4968) PF17137 (DUF5110)	7	ASP A 441 TRP A 551 ASP A 553 ARG A 613 ASP A 630 PHE A 663 HIS A 709	EDO  A1008 (-2.8A) None EDO  A1008 (-2.7A) EDO  A1008 (-4.6A) EDO  A1008 (-3.0A) EDO  A1008 (-4.3A) EDO  A1008 (-4.0A)	0.39A	3weoA-5jouA: 36.7	3weoA-5jouA: 25.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5nn8	LYSOSOMAL ALPHA-GLUCOSIDASE (Homo sapiens)	no annotation	6	ASP A 282 ALA A 284 ASP A 404 ILE A 441 ASP A 616 PHE A 649	ACR  A1015 (-2.6A) ACR  A1015 ( 4.6A) ACR  A1015 (-3.0A) ACR  A1015 (-4.3A) ACR  A1015 (-2.7A) ACR  A1015 (-4.3A)	1.41A	3weoA-5nn8A: 53.3	3weoA-5nn8A: 37.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5nn8	LYSOSOMAL ALPHA-GLUCOSIDASE (Homo sapiens)	no annotation	9	ASP A 282 ALA A 284 ASP A 404 TRP A 516 ASP A 518 ARG A 600 ASP A 616 PHE A 649 HIS A 674	ACR  A1015 (-2.6A) ACR  A1015 ( 4.6A) ACR  A1015 (-3.0A) None ACR  A1015 (-3.1A) ACR  A1015 (-3.1A) ACR  A1015 (-2.7A) ACR  A1015 (-4.3A) ACR  A1015 (-4.0A)	0.28A	3weoA-5nn8A: 53.3	3weoA-5nn8A: 37.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ogl	UNDECAPRENYL-DIPHOSP HOOLIGOSACCHARIDE--P ROTEIN GLYCOTRANSFERASE (Campylobacter lari)	no annotation	5	ASP A 481 ALA A  59 PHE A  60 ARG A 471 HIS A  72	None 9UB  A 803 ( 3.8A) 9UB  A 803 ( 4.4A) None None	0.95A	3weoA-5oglA: undetectable	3weoA-5oglA: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5uf2	RIBOSE-5-PHOSPHATE ISOMERASE A (Neisseria gonorrhoeae)	PF06026 (Rib_5-P_isom_A)	5	ALA A  84 ASP A 171 ILE A 169 ASP A  85 PHE A 130	None None None EDO  A 306 (-3.5A) None	1.49A	3weoA-5uf2A: undetectable	3weoA-5uf2A: 13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5vev	PHOSPHORIBOSYLAMINE- -GLYCINE LIGASE (Neisseria gonorrhoeae)	PF01071 (GARS_A) PF02843 (GARS_C) PF02844 (GARS_N)	5	ASP A 291 ALA A 364 ASN A  34 ILE A 416 ARG A 380	None None None None SO4  A 511 (-3.8A)	1.29A	3weoA-5vevA: undetectable	3weoA-5vevA: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5x7s	GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE (Paenibacillus sp. 598K)	PF01055 (Glyco_hydro_31) PF16338 (DUF4968) PF16990 (CBM_35) PF17137 (DUF5110)	6	TRP A 427 ASP A 429 ARG A 474 ASP A 491 PHE A 533 HIS A 565	None	0.49A	3weoA-5x7sA: 32.1	3weoA-5x7sA: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1b1y	PROTEIN (BETA-AMYLASE) (Hordeum vulgare)	PF01373 (Glyco_hydro_14)	4	ILE A 294 TRP A 196 ILE A 201 TRP A 299	None	1.12A	3weoA-1b1yA: 2.9	3weoA-1b1yA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1dpp	DIPEPTIDE BINDING PROTEIN (Escherichia coli)	PF00496 (SBP_bac_5)	4	ILE A 474 ILE A 381 MET A 402 TRP A 372	None	0.80A	3weoA-1dppA: undetectable	3weoA-1dppA: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1fft	UBIQUINOL OXIDASE (Escherichia coli)	PF00115 (COX1)	4	ILE A 109 TRP A 282 ILE A 239 MET A 116	None	1.41A	3weoA-1fftA: undetectable	3weoA-1fftA: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1uyp	BETA-FRUCTOSIDASE (Thermotoga maritima)	PF00251 (Glyco_hydro_32N) PF08244 (Glyco_hydro_32C)	4	ILE A 404 TRP A  14 TRP A 256 TRP A 273	None	1.43A	3weoA-1uypA: undetectable	3weoA-1uypA: 18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1vft	ALANINE RACEMASE (Streptomyces lavendulae)	PF00842 (Ala_racemase_C) PF01168 (Ala_racemase_N)	4	ILE A 206 ILE A  81 TRP A  60 TRP A  84	None None None DCS  A 401 ( 3.9A)	1.44A	3weoA-1vftA: 2.9	3weoA-1vftA: 18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1zkd	DUF185 (Rhodopseudomonas palustris)	PF02636 (Methyltransf_28)	4	ILE A  87 ILE A 134 MET A  95 TRP A 139	None	0.78A	3weoA-1zkdA: undetectable	3weoA-1zkdA: 17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1zmb	ACETYLXYLAN ESTERASE RELATED ENZYME (Clostridium acetobutylicum)	PF03629 (SASA)	4	ILE A 114 ILE A  72 TRP A  38 TRP A  64	None	1.42A	3weoA-1zmbA: undetectable	3weoA-1zmbA: 15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2aey	FRUCTAN 1-EXOHYDROLASE IIA (Cichorium intybus)	PF00251 (Glyco_hydro_32N) PF08244 (Glyco_hydro_32C)	4	ILE A 452 TRP A  19 TRP A 292 TRP A 307	None	1.27A	3weoA-2aeyA: undetectable	3weoA-2aeyA: 20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2amg	1,4-ALPHA-D-GLUCAN MALTOTETRAHYDROLASE (Pseudomonas stutzeri)	PF00128 (Alpha-amylase) PF09081 (DUF1921)	4	ILE A 315 TRP A  55 ILE A  54 TRP A 333	None	1.50A	3weoA-2amgA: undetectable	3weoA-2amgA: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2g3n	ALPHA-GLUCOSIDASE (Sulfolobus solfataricus)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	4	ILE A 249 TRP A 284 MET A 321 TRP A 413	None None BOG  A2000 ( 4.0A) None	0.42A	3weoA-2g3nA: 37.4	3weoA-2g3nA: 26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2nsm	CARBOXYPEPTIDASE N CATALYTIC CHAIN (Homo sapiens)	PF00246 (Peptidase_M14) PF13620 (CarboxypepD_reg)	4	ILE A 285 TRP A 183 ILE A 181 MET A 272	None	1.15A	3weoA-2nsmA: undetectable	3weoA-2nsmA: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2p2m	ACETYL-COENZYME A SYNTHETASE (Salmonella enterica)	PF00501 (AMP-binding) PF13193 (AMP-binding_C) PF16177 (ACAS_N)	4	ILE A  67 TRP A  48 ILE A  45 TRP A  39	None	1.17A	3weoA-2p2mA: undetectable	3weoA-2p2mA: 21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2uvj	ABC TYPE PERIPLASMIC SUGAR-BINDING PROTEIN (Yersinia enterocolitica)	PF13416 (SBP_bac_8)	4	ILE A 138 ILE A  78 MET A  87 TRP A  93	None	1.44A	3weoA-2uvjA: undetectable	3weoA-2uvjA: 18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2xy3	SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS (Bacillus subtilis)	PF00692 (dUTPase)	4	ILE A 108 ILE A 113 TRP A  23 TRP A  90	None	1.33A	3weoA-2xy3A: 2.0	3weoA-2xy3A: 8.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ctt	MALTASE-GLUCOAMYLASE (Homo sapiens)	PF00088 (Trefoil) PF01055 (Glyco_hydro_31) PF16863 (NtCtMGAM_N)	4	ILE A 364 TRP A 406 MET A 444 TRP A 539	3CU  A1001 (-4.5A) None 3CU  A1001 ( 3.9A) 3CU  A1001 (-4.6A)	0.47A	3weoA-3cttA: 55.0	3weoA-3cttA: 36.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3gnr	OS03G0212800 PROTEIN (Oryza sativa)	PF00232 (Glyco_hydro_1)	4	ILE A 174 ILE A  45 TRP A 146 TRP A 452	ILE  A 174 ( 0.6A) ILE  A  45 ( 0.7A) TRP  A 146 ( 0.5A) TRP  A 452 (-0.5A)	1.43A	3weoA-3gnrA: 6.0	3weoA-3gnrA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3h7k	AGMATINE DEIMINASE (Arabidopsis thaliana)	PF04371 (PAD_porph)	4	ILE A 209 TRP A 241 ILE A 278 MET A 228	None	1.37A	3weoA-3h7kA: undetectable	3weoA-3h7kA: 17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3hkz	DNA-DIRECTED RNA POLYMERASE SUBUNIT B (Sulfolobus solfataricus)	PF00562 (RNA_pol_Rpb2_6) PF04560 (RNA_pol_Rpb2_7) PF04561 (RNA_pol_Rpb2_2) PF04563 (RNA_pol_Rpb2_1) PF04565 (RNA_pol_Rpb2_3) PF04566 (RNA_pol_Rpb2_4) PF04567 (RNA_pol_Rpb2_5)	4	ILE B 655 TRP B  11 ILE B   7 TRP B 643	None	0.91A	3weoA-3hkzB: undetectable	3weoA-3hkzB: 22.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3lpp	SUCRASE-ISOMALTASE (Homo sapiens)	PF00088 (Trefoil) PF01055 (Glyco_hydro_31) PF16863 (NtCtMGAM_N)	5	TRP A 327 ILE A 392 TRP A 435 MET A 473 TRP A 568	TRS  A6001 ( 3.8A) None TRS  A6001 ( 4.6A) TRS  A6001 ( 3.7A) None	0.31A	3weoA-3lppA: 49.2	3weoA-3lppA: 35.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3mzs	CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME (Bos taurus)	PF00067 (p450)	4	ILE A 196 ILE A  85 TRP A 232 MET A 202	None	1.50A	3weoA-3mzsA: undetectable	3weoA-3mzsA: 19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3n9o	PUTATIVE UNCHARACTERIZED PROTEIN (Caenorhabditis elegans)	PF02373 (JmjC)	4	ILE A 688 TRP A 650 ILE A 649 MET A 624	None	1.49A	3weoA-3n9oA: undetectable	3weoA-3n9oA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3na0	CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME, MITOCHONDRIAL (Homo sapiens)	PF00067 (p450)	4	ILE A 234 ILE A 123 TRP A 270 MET A 240	None	1.43A	3weoA-3na0A: undetectable	3weoA-3na0A: 19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3njx	RHAMNOGALACTURONASE B (Aspergillus aculeatus)	PF09284 (RhgB_N) PF14683 (CBM-like) PF14686 (fn3_3)	4	ILE A 238 ILE A  51 MET A  93 TRP A 204	None	1.36A	3weoA-3njxA: undetectable	3weoA-3njxA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3poc	ALPHA-GLUCOSIDASE (Blautia obeum)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	5	TRP A 169 ILE A 234 TRP A 271 MET A 308 TRP A 417	ACR  A 664 (-3.7A) None ACR  A 664 (-4.6A) ACR  A 664 ( 3.8A) ACR  A 664 (-4.6A)	0.45A	3weoA-3pocA: 42.3	3weoA-3pocA: 26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3sil	SIALIDASE (Salmonella enterica)	PF13859 (BNR_3)	4	ILE A  86 ILE A 164 TRP A 218 TRP A 140	None	1.24A	3weoA-3silA: undetectable	3weoA-3silA: 18.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3top	MALTASE-GLUCOAMYLASE , INTESTINAL (Homo sapiens)	PF00088 (Trefoil) PF01055 (Glyco_hydro_31) PF16863 (NtCtMGAM_N)	4	ILE A1315 TRP A1355 MET A1421 TRP A1523	None ACR  A   1 (-4.4A) ACR  A   1 (-3.5A) ACR  A   1 (-4.5A)	0.36A	3weoA-3topA: 45.0	3weoA-3topA: 34.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3uug	MULTIPLE SUGAR-BINDING PERIPLASMIC RECEPTOR CHVE (Agrobacterium fabrum)	PF13407 (Peripla_BP_4)	4	ILE A  88 ILE A  19 TRP A  18 MET A  10	None None BDP  A 331 ( 4.9A) None	1.25A	3weoA-3uugA: undetectable	3weoA-3uugA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	PF09485 (CRISPR_Cse2)	4	ILE A 128 ILE A 157 MET A 145 TRP A 180	None	1.08A	3weoA-3wa8A: undetectable	3weoA-3wa8A: 12.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3wel	ALPHA-GLUCOSIDASE (Beta vulgaris)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2) PF16863 (NtCtMGAM_N)	6	ILE A 233 TRP A 329 ILE A 396 TRP A 432 MET A 470 TRP A 565	GLC  A1002 (-3.9A) ACR  A1001 (-4.1A) ACR  A1001 (-4.9A) ACR  A1001 ( 4.6A) ACR  A1001 (-3.3A) ACR  A1001 (-4.8A)	0.11A	3weoA-3welA: 62.1	3weoA-3welA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4er8	TNPAREP FOR PROTEIN (Escherichia coli)	no annotation	4	ILE A  93 TRP A  64 TRP A  53 MET A  60	None	1.39A	3weoA-4er8A: undetectable	3weoA-4er8A: 11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4f53	SUSD HOMOLOG (Bacteroides ovatus)	PF12741 (SusD-like)	4	ILE A 386 ILE A 283 MET A 291 TRP A 455	None	1.32A	3weoA-4f53A: undetectable	3weoA-4f53A: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4f7a	PUTATIVE UNCHARACTERIZED PROTEIN (Bacteroides vulgatus)	PF12741 (SusD-like)	4	ILE A 267 TRP A 458 ILE A 455 TRP A 397	None	1.13A	3weoA-4f7aA: undetectable	3weoA-4f7aA: 20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ry1	PERIPLASMIC SOLUTE BINDING PROTEIN (Pectobacterium atrosepticum)	PF13416 (SBP_bac_8)	4	ILE A  61 TRP A  37 ILE A 141 MET A 337	None	1.26A	3weoA-4ry1A: undetectable	3weoA-4ry1A: 18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5aif	LIMONENE-1,2-EPOXIDE HYDROLASE (unidentified)	PF07858 (LEH)	4	TRP A  32 ILE A 106 TRP A  14 MET A  22	None	1.11A	3weoA-5aifA: undetectable	3weoA-5aifA: 9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5dkx	ALPHA GLUCOSIDASE-LIKE PROTEIN (Chaetomium thermophilum)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2) PF17137 (DUF5110)	5	TRP A 415 ILE A 480 TRP A 517 MET A 557 TRP A 630	None None TRS  A1001 ( 4.9A) TRS  A1001 (-3.5A) None	0.41A	3weoA-5dkxA: 38.7	3weoA-5dkxA: 27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5evy	SALICYLATE HYDROXYLASE (Pseudomonas putida)	PF01494 (FAD_binding_3)	4	ILE X 220 TRP X  82 ILE X  81 TRP X  85	None	1.39A	3weoA-5evyX: undetectable	3weoA-5evyX: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5hjr	NEUTRAL ALPHA-GLUCOSIDASE AB (Mus musculus)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	5	TRP A 423 ILE A 488 TRP A 525 MET A 565 TRP A 637	5GF  A1021 (-3.1A) None 5GF  A1021 (-3.7A) 5GF  A1021 (-2.6A) 5GF  A1021 ( 4.6A)	0.43A	3weoA-5hjrA: 50.1	3weoA-5hjrA: 29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5jbo	BETA-GLUCOSIDASE (Trichoderma harzianum)	PF00232 (Glyco_hydro_1)	4	ILE A 168 ILE A  36 TRP A 139 TRP A 442	None	1.47A	3weoA-5jboA: 7.2	3weoA-5jboA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5k34	ANKYRIN-REPEAT PROTEIN B (Legionella pneumophila)	no annotation	4	ILE A 102 ILE A  78 TRP A  60 MET A  64	None	1.32A	3weoA-5k34A: undetectable	3weoA-5k34A: 8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5k35	ANKYRIN-REPEAT PROTEIN B (Legionella pneumophila)	PF12937 (F-box-like)	4	ILE A 102 ILE A  78 TRP A  60 MET A  64	None	1.43A	3weoA-5k35A: undetectable	3weoA-5k35A: 12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	PF00128 (Alpha-amylase)	4	ILE B  35 ILE B 203 TRP B 202 MET B 117	None	1.40A	3weoA-5m99B: 13.5	3weoA-5m99B: 20.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5nn8	LYSOSOMAL ALPHA-GLUCOSIDASE (Homo sapiens)	no annotation	5	TRP A 376 ILE A 441 TRP A 481 MET A 519 TRP A 613	ACR  A1015 ( 4.6A) ACR  A1015 (-4.3A) ACR  A1015 ( 4.6A) ACR  A1015 (-3.3A) ACR  A1015 (-4.8A)	0.72A	3weoA-5nn8A: 53.3	3weoA-5nn8A: 37.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5no5	ABYA5 (Verrucosispora)	no annotation	4	ILE A 236 ILE A 161 TRP A 158 MET A 147	None	1.44A	3weoA-5no5A: undetectable	3weoA-5no5A: 7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5tub	SHARK TBC1D15 GTPASE-ACTIVATING PROTEIN (Squalimorphii)	PF00566 (RabGAP-TBC)	4	TRP A 573 ILE A 362 TRP A 376 TRP A 385	None	1.44A	3weoA-5tubA: undetectable	3weoA-5tubA: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5uld	TRANSPORTER, NADC FAMILY (Vibrio cholerae)	PF00939 (Na_sulph_symp)	4	ILE A 149 TRP A 217 ILE A  96 TRP A 275	None	1.49A	3weoA-5uldA: undetectable	3weoA-5uldA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ww1	PULULLANASE (Paenibacillus barengoltzii)	no annotation	4	ILE A 300 TRP A 165 ILE A 282 TRP A 361	None	1.36A	3weoA-5ww1A: 12.6	3weoA-5ww1A: 7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5xl2	HEMAGGLUTININ (Influenza A virus)	PF00509 (Hemagglutinin)	4	ILE A 372 TRP A 341 ILE A 321 MET A 318	None	1.43A	3weoA-5xl2A: undetectable	3weoA-5xl2A: 20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5xp0	PROBABLE CSGAB OPERON TRANSCRIPTIONAL REGULATORY PROTEIN (Salmonella enterica)	no annotation	4	ILE A  55 ILE A  68 TRP A  71 MET A  58	None	1.19A	3weoA-5xp0A: 2.0	3weoA-5xp0A: 6.35