SIMILAR PATTERNS OF AMINO ACIDS FOR 3WDM_D_ADND301_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dc1 | BSOBI RESTRICTIONENDONUCLEASE (Geobacillusstearothermophilus) |
PF09194(Endonuc-BsobI) | 5 | ALA A 145LEU A 198LEU A 142LEU A 316ILE A 213 | None | 1.16A | 3wdmD-1dc1A:undetectable | 3wdmD-1dc1A:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ebb | PHOSPHATASE (Geobacillusstearothermophilus) |
PF00300(His_Phos_1) | 5 | ALA A 130LEU A 7LEU A 81ASP A 78ILE A 148 | None | 1.14A | 3wdmD-1ebbA:undetectable | 3wdmD-1ebbA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f0p | ANTIGEN 85-B (Mycobacteriumtuberculosis) |
PF00756(Esterase) | 5 | ALA A 57GLY A 268LEU A 38ASN A 54ILE A 123 | None | 1.12A | 3wdmD-1f0pA:1.9 | 3wdmD-1f0pA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f6d | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Escherichiacoli) |
PF02350(Epimerase_2) | 5 | ARG A 40LEU A 4LEU A 58ASN A 59ILE A 81 | None | 1.13A | 3wdmD-1f6dA:5.6 | 3wdmD-1f6dA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fp9 | 4-ALPHA-GLUCANOTRANSFERASE (Thermusthermophilus) |
PF02446(Glyco_hydro_77) | 5 | ALA A 29GLY A 23LEU A 49LEU A 25ASP A 73 | None | 1.03A | 3wdmD-1fp9A:undetectable | 3wdmD-1fp9A:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kl7 | THREONINE SYNTHASE (Saccharomycescerevisiae) |
PF00291(PALP)PF14821(Thr_synth_N) | 5 | GLY A 426LEU A 110LEU A 419ASP A 420ILE A 112 | None | 1.17A | 3wdmD-1kl7A:undetectable | 3wdmD-1kl7A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n7f | AMPA RECEPTORINTERACTING PROTEINGRIP (Rattusnorvegicus) |
PF00595(PDZ) | 5 | GLY A 743LEU A 748LEU A 739ASN A 723ILE A 722 | None | 1.14A | 3wdmD-1n7fA:undetectable | 3wdmD-1n7fA:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o8c | YHDH (Escherichiacoli) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 141ARG A 261GLY A 235LEU A 138ILE A 150 | None | 1.13A | 3wdmD-1o8cA:2.2 | 3wdmD-1o8cA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1odf | HYPOTHETICAL 33.3KDA PROTEIN INADE3-SER2 INTERGENICREGION (Saccharomycescerevisiae) |
no annotation | 5 | ALA A 269GLY A 266LEU A 32LEU A 265ILE A 34 | None | 1.09A | 3wdmD-1odfA:undetectable | 3wdmD-1odfA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qdl | PROTEIN(ANTHRANILATESYNTHASE(TRPE-SUBUNIT)) (Sulfolobussolfataricus) |
PF00425(Chorismate_bind)PF04715(Anth_synt_I_N) | 5 | ALA A 321LEU A 325LEU A 62ASN A 63ILE A 86 | None | 1.17A | 3wdmD-1qdlA:undetectable | 3wdmD-1qdlA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qdl | PROTEIN(ANTHRANILATESYNTHASE(TRPG-SUBUNIT)) (Sulfolobussolfataricus) |
PF00117(GATase) | 5 | GLY B 171LEU B 188LEU B 122ASP B 150ILE B 187 | None | 1.15A | 3wdmD-1qdlB:2.3 | 3wdmD-1qdlB:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qh1 | PROTEIN (NITROGENASEMOLYBDENUM IRONPROTEIN) (Klebsiellapneumoniae) |
PF00148(Oxidored_nitro)PF11844(DUF3364) | 5 | ALA B 496LEU B 465LEU B 493ASN B 488ILE B 489 | None | 1.07A | 3wdmD-1qh1B:undetectable | 3wdmD-1qh1B:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tz7 | 4-ALPHA-GLUCANOTRANSFERASE (Aquifexaeolicus) |
PF02446(Glyco_hydro_77) | 5 | ALA A 26GLY A 20LEU A 46LEU A 22ASP A 72 | None | 1.14A | 3wdmD-1tz7A:undetectable | 3wdmD-1tz7A:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wv2 | THIAZOLEBIOSYNTHESIS PROTEINTHIG (Pseudomonasaeruginosa) |
PF05690(ThiG) | 5 | ALA A1096LEU A1100LEU A1105ASN A1104ILE A1076 | None | 1.16A | 3wdmD-1wv2A:undetectable | 3wdmD-1wv2A:24.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y2f | CELL DIVISIONPROTEIN ZIPA (Escherichiacoli) |
PF04354(ZipA_C) | 5 | GLY A 81LEU A 29LEU A 61ASN A 14ILE A 32 | None | 1.06A | 3wdmD-1y2fA:undetectable | 3wdmD-1y2fA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b42 | XYLANASE INHIBITOR-I (Triticumaestivum) |
PF14541(TAXi_C)PF14543(TAXi_N) | 5 | ALA A 345ARG A 244LEU A 302LEU A 227ILE A 213 | None | 1.18A | 3wdmD-2b42A:undetectable | 3wdmD-2b42A:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d6y | PUTATIVE TETR FAMILYREGULATORY PROTEIN (Streptomycescoelicolor) |
PF00440(TetR_N) | 5 | ALA A 127GLY A 131LEU A 150ASP A 76ILE A 78 | None | 1.14A | 3wdmD-2d6yA:undetectable | 3wdmD-2d6yA:26.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2et6 | (3R)-HYDROXYACYL-COADEHYDROGENASE (Candidatropicalis) |
PF00106(adh_short) | 5 | ALA A 403GLY A 429LEU A 326ASP A 377ILE A 385 | None | 1.13A | 3wdmD-2et6A:2.6 | 3wdmD-2et6A:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fym | ENOLASE (Escherichiacoli) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | ALA A 247GLY A 291LEU A 259ASP A 293LEU A 292 | None | 1.01A | 3wdmD-2fymA:undetectable | 3wdmD-2fymA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ghi | TRANSPORT PROTEIN (Plasmodiumyoelii) |
PF00005(ABC_tran) | 5 | GLY A 153LEU A 141LEU A 156ASN A 151ILE A 109 | None | 1.12A | 3wdmD-2ghiA:undetectable | 3wdmD-2ghiA:25.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsn | PHOSPHODIESTERASE-NUCLEOTIDEPYROPHOSPHATASE (Xanthomonascitri) |
PF01663(Phosphodiest) | 5 | ALA A 233ARG A 236GLY A 235LEU A 238ILE A 51 | None | 1.13A | 3wdmD-2gsnA:undetectable | 3wdmD-2gsnA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h7v | PROTEIN KINASE YPKA (Yersiniapseudotuberculosis) |
PF09632(Rac1) | 5 | ALA C 565LEU C 477ASP C 481ASN C 498ILE C 501 | None | 1.09A | 3wdmD-2h7vC:undetectable | 3wdmD-2h7vC:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hyp | HYPOTHETICAL PROTEINRV0805 (Mycobacteriumtuberculosis) |
PF00149(Metallophos) | 5 | ALA A 190ARG A 193GLY A 192LEU A 149LEU A 195 | None | 1.16A | 3wdmD-2hypA:undetectable | 3wdmD-2hypA:24.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ihy | ABC TRANSPORTER,ATP-BINDING PROTEIN (Staphylococcusaureus) |
PF00005(ABC_tran) | 5 | ALA A 50ARG A 77LEU A 5LEU A 61ILE A 3 | None | 1.17A | 3wdmD-2ihyA:undetectable | 3wdmD-2ihyA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iip | NICOTINAMIDEN-METHYLTRANSFERASE (Homo sapiens) |
PF01234(NNMT_PNMT_TEMT) | 6 | ALA A 228ARG A 181LEU A 255LEU A 183ASN A 182ILE A 195 | None | 1.33A | 3wdmD-2iipA:undetectable | 3wdmD-2iipA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j8k | NP275-NP276 (Nostocpunctiforme) |
PF00805(Pentapeptide) | 5 | ALA A 105LEU A 92LEU A 102LEU A 62ASN A 63 | None | 1.16A | 3wdmD-2j8kA:undetectable | 3wdmD-2j8kA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j8k | NP275-NP276 (Nostocpunctiforme) |
PF00805(Pentapeptide) | 5 | ALA A 105LEU A 112LEU A 122ASP A 121ILE A 117 | None | 1.04A | 3wdmD-2j8kA:undetectable | 3wdmD-2j8kA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j8k | NP275-NP276 (Nostocpunctiforme) |
PF00805(Pentapeptide) | 5 | ALA A 125LEU A 112LEU A 122ASP A 121ILE A 117 | None | 1.00A | 3wdmD-2j8kA:undetectable | 3wdmD-2j8kA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j8k | NP275-NP276 (Nostocpunctiforme) |
PF00805(Pentapeptide) | 5 | ALA A 140LEU A 127LEU A 137LEU A 97ASN A 98 | NoneNoneNoneNoneMES A1176 (-2.7A) | 0.97A | 3wdmD-2j8kA:undetectable | 3wdmD-2j8kA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j8k | NP275-NP276 (Nostocpunctiforme) |
PF00805(Pentapeptide) | 5 | ALA A 145LEU A 132ASP A 121LEU A 102ILE A 117 | None | 1.10A | 3wdmD-2j8kA:undetectable | 3wdmD-2j8kA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o5v | DNA REPLICATION ANDREPAIR PROTEIN RECF (Deinococcusradiodurans) |
PF02463(SMC_N) | 5 | GLY A 343LEU A 338LEU A 42ASN A 16ILE A 31 | None | 1.06A | 3wdmD-2o5vA:undetectable | 3wdmD-2o5vA:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q27 | OXALYL-COADECARBOXYLASE (Escherichiacoli) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ALA A 204LEU A 208LEU A 333ASN A 336ILE A 240 | None | 1.12A | 3wdmD-2q27A:11.3 | 3wdmD-2q27A:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2reb | REC A (Escherichiacoli) |
PF00154(RecA) | 5 | GLY A 55LEU A 45LEU A 328LEU A 51ILE A 49 | None | 1.17A | 3wdmD-2rebA:undetectable | 3wdmD-2rebA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w9m | POLYMERASE X (Deinococcusradiodurans) |
PF14520(HHH_5)PF14716(HHH_8) | 5 | ALA A 238GLY A 204LEU A 224LEU A 180ILE A 235 | None | 1.09A | 3wdmD-2w9mA:undetectable | 3wdmD-2w9mA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x1i | 4-ALPHA-GLUCANOTRANSFERASE (Thermusbrockianus) |
PF02446(Glyco_hydro_77) | 5 | ALA A 29GLY A 23LEU A 49LEU A 25ASP A 73 | None | 1.03A | 3wdmD-2x1iA:undetectable | 3wdmD-2x1iA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xym | RNA-DIRECTED RNAPOLYMERASE (Hepacivirus C) |
PF00998(RdRP_3) | 5 | ALA A 519ARG A 523GLY A 522LEU A 439LEU A 525 | None | 1.12A | 3wdmD-2xymA:undetectable | 3wdmD-2xymA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bwx | ALPHA/BETA HYDROLASE (Novosphingobiumaromaticivorans) |
PF12697(Abhydrolase_6) | 5 | ALA A 276ARG A 279GLY A 278LEU A 47ILE A 101 | None | 1.09A | 3wdmD-3bwxA:undetectable | 3wdmD-3bwxA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bwx | ALPHA/BETA HYDROLASE (Novosphingobiumaromaticivorans) |
PF12697(Abhydrolase_6) | 5 | ALA A 276ARG A 279GLY A 278LEU A 281ILE A 101 | None | 0.92A | 3wdmD-3bwxA:undetectable | 3wdmD-3bwxA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cl6 | PUUE ALLANTOINASE (Pseudomonasfluorescens) |
PF01522(Polysacc_deac_1) | 5 | ALA A 271ARG A 274LEU A 258LEU A 236ILE A 256 | None | 1.18A | 3wdmD-3cl6A:undetectable | 3wdmD-3cl6A:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1j | GLYCOGEN SYNTHASE (Escherichiacoli) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 5 | ALA A 54LEU A 13LEU A 81ASP A 83ILE A 47 | None | 1.14A | 3wdmD-3d1jA:4.3 | 3wdmD-3d1jA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3du1 | ALL3740 PROTEIN (Nostoc sp. PCC7120) |
PF00805(Pentapeptide) | 5 | ALA X 160LEU X 147LEU X 157LEU X 112ASN X 113 | None | 1.07A | 3wdmD-3du1X:undetectable | 3wdmD-3du1X:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eya | PYRUVATEDEHYDROGENASE[CYTOCHROME] (Escherichiacoli) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | LEU A 13LEU A 36LEU A 29ASN A 30ILE A 21 | None | 1.16A | 3wdmD-3eyaA:10.4 | 3wdmD-3eyaA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gcf | TERMINAL OXYGENASECOMPONENT OFCARBAZOLE1,9A-DIOXYGENASE (Nocardioidesaromaticivorans) |
PF00355(Rieske)PF11723(Aromatic_hydrox) | 5 | ALA A 64LEU A 60LEU A 105ASP A 106ILE A 71 | None | 1.08A | 3wdmD-3gcfA:undetectable | 3wdmD-3gcfA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h4p | PROTEASOME SUBUNITBETA (Methanocaldococcusjannaschii) |
PF00227(Proteasome)PF10584(Proteasome_A_N) | 5 | ALA a 60ARG a 63LEU a 93LEU a 65ILE a 92 | None | 0.91A | 3wdmD-3h4pa:undetectable | 3wdmD-3h4pa:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hut | PUTATIVEBRANCHED-CHAIN AMINOACID ABC TRANSPORTER (Rhodospirillumrubrum) |
PF13458(Peripla_BP_6) | 5 | ALA A 321GLY A 323LEU A 113LEU A 326ILE A 84 | None | 0.96A | 3wdmD-3hutA:undetectable | 3wdmD-3hutA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hut | PUTATIVEBRANCHED-CHAIN AMINOACID ABC TRANSPORTER (Rhodospirillumrubrum) |
PF13458(Peripla_BP_6) | 5 | ALA A 328ARG A 331GLY A 330LEU A 43LEU A 341 | None | 1.09A | 3wdmD-3hutA:undetectable | 3wdmD-3hutA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3khf | MICROTUBULE-ASSOCIATEDSERINE/THREONINE-PROTEIN KINASE 3 (Homo sapiens) |
PF00595(PDZ) | 5 | GLY A1027LEU A1032LEU A1023ASN A1007ILE A1006 | None | 1.15A | 3wdmD-3khfA:undetectable | 3wdmD-3khfA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l0g | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE (Ehrlichiachaffeensis) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | ALA A 86GLY A 84LEU A 52ASN A 35ILE A 38 | None | 1.04A | 3wdmD-3l0gA:undetectable | 3wdmD-3l0gA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mq3 | PYRUVATEDEHYDROGENASEPHOSPHATASE 1 (Bos taurus) |
PF00481(PP2C) | 5 | ALA A 203GLY A 70LEU A 165LEU A 88ILE A 92 | None | 0.98A | 3wdmD-3mq3A:undetectable | 3wdmD-3mq3A:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nqn | UNCHARACTERIZEDPROTEIN (Deinococcusradiodurans) |
PF12723(DUF3809) | 5 | ALA A 134ARG A 137GLY A 136LEU A 114LEU A 139 | None | 1.15A | 3wdmD-3nqnA:undetectable | 3wdmD-3nqnA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pao | ADENOSINE DEAMINASE (Pseudomonasaeruginosa) |
PF00962(A_deaminase) | 5 | ALA A 224GLY A 221LEU A 210LEU A 234ILE A 239 | None | 1.12A | 3wdmD-3paoA:undetectable | 3wdmD-3paoA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qdl | OXYGEN-INSENSITIVENADPH NITROREDUCTASE (Helicobacterpylori) |
PF00881(Nitroreductase) | 5 | ALA A 80LEU A 33LEU A 188LEU A 156ILE A 36 | None | 1.14A | 3wdmD-3qdlA:undetectable | 3wdmD-3qdlA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rr5 | DNA LIGASE (Thermococcussp. 1519) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 5 | GLY A 309LEU A 353LEU A 349ASN A 348ILE A 352 | None | 1.08A | 3wdmD-3rr5A:undetectable | 3wdmD-3rr5A:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v9a | ESTERASE/LIPASE (unculturedbacterium) |
PF07859(Abhydrolase_3) | 5 | GLY A 148LEU A 230LEU A 247ASP A 243ILE A 232 | None | 0.91A | 3wdmD-3v9aA:undetectable | 3wdmD-3v9aA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vx4 | PUTATIVE ABCTRANSPORTER,ATP-BINDING PROTEINCOMA (Streptococcusmutans) |
PF00005(ABC_tran) | 5 | ALA A 599ARG A 602LEU A 592LEU A 524ILE A 587 | None | 1.12A | 3wdmD-3vx4A:undetectable | 3wdmD-3vx4A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wnv | GLYOXYLATE REDUCTASE (Paecilomycessp.'thermophila') |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | ALA A 252ARG A 255LEU A 230LEU A 257ILE A 239 | None | 0.88A | 3wdmD-3wnvA:3.0 | 3wdmD-3wnvA:24.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zdf | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Thermosynechococcuselongatus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | ALA A 99GLY A 10ASN A 15ASN A 43ILE A 34 | NAD A1001 (-4.9A)NAD A1001 (-3.1A)NoneNoneNone | 1.14A | 3wdmD-3zdfA:3.2 | 3wdmD-3zdfA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aee | ALPHA AMYLASE,CATALYTIC REGION (Staphylothermusmarinus) |
PF00128(Alpha-amylase) | 5 | ALA A 494ARG A 512LEU A 556LEU A 491ASN A 515 | None | 1.07A | 3wdmD-4aeeA:undetectable | 3wdmD-4aeeA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ayx | ATP-BINDING CASSETTESUB-FAMILY B MEMBER10 (Homo sapiens) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 5 | ALA A 461ARG A 464GLY A 463LEU A 160LEU A 282 | None | 1.14A | 3wdmD-4ayxA:undetectable | 3wdmD-4ayxA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e2o | ALPHA-AMYLASE (Geobacillusthermoleovorans) |
PF00128(Alpha-amylase) | 5 | LEU A 138LEU A 70ASP A 69ASN A 47ILE A 93 | None | 1.14A | 3wdmD-4e2oA:undetectable | 3wdmD-4e2oA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ep0 | MAJOR TAIL PROTEIN (Streptococcusvirus C1) |
PF16838(Caud_tail_N) | 5 | GLY A 294ASP A 300LEU A 295ASN A 296ILE A 308 | None | 1.16A | 3wdmD-4ep0A:undetectable | 3wdmD-4ep0A:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0s | 5-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE DEAMINASE (Chromobacteriumviolaceum) |
PF01979(Amidohydro_1) | 5 | ALA A 301ARG A 353GLY A 351LEU A 355ASN A 128 | NoneNOS A 502 (-4.4A)NoneNoneNone | 1.15A | 3wdmD-4f0sA:undetectable | 3wdmD-4f0sA:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fgm | AMINOPEPTIDASE NFAMILY PROTEIN (Idiomarinaloihiensis) |
PF05299(Peptidase_M61)PF13180(PDZ_2) | 5 | ALA A 489LEU A 561LEU A 514LEU A 498ILE A 548 | None | 1.16A | 3wdmD-4fgmA:undetectable | 3wdmD-4fgmA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fvl | COLLAGENASE 3 (Homo sapiens) |
PF00045(Hemopexin)PF00413(Peptidase_M10) | 5 | ALA A 465LEU A 290ASP A 432ASN A 445ILE A 293 | NoneNoneGOL A 512 ( 3.2A)NoneNone | 1.12A | 3wdmD-4fvlA:undetectable | 3wdmD-4fvlA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g2r | ACCD6,CARBOXYLTRANSFERASEBETA-SUBUNIT OFACYL-COA CARBOXYLASE (Mycobacteriumtuberculosis) |
PF01039(Carboxyl_trans) | 5 | ALA A 223GLY A 226LEU A 276ASP A 253ILE A 251 | None | 1.08A | 3wdmD-4g2rA:undetectable | 3wdmD-4g2rA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ho4 | GLUCOSE-1-PHOSPHATETHYMIDYLYLTRANSFERASE (Aneurinibacillusthermoaerophilus) |
PF00483(NTP_transferase) | 5 | GLY A 172LEU A 41ASP A 108LEU A 106ILE A 5 | G1P A 301 ( 4.2A)NoneTHM A 302 (-3.5A)THM A 302 (-4.2A)None | 1.17A | 3wdmD-4ho4A:undetectable | 3wdmD-4ho4A:24.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ib4 | CHIMERA PROTEIN OFHUMAN5-HYDROXYTRYPTAMINERECEPTOR 2B AND E.COLI SOLUBLECYTOCHROME B562 (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 5 | ALA A 390ARG A 393GLY A 392LEU A 378ASN A 398 | None | 0.97A | 3wdmD-4ib4A:undetectable | 3wdmD-4ib4A:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0e | PROBABLE3-HYDROXYACYL-COADEHYDROGENASEF54C8.1 (Caenorhabditiselegans) |
PF00725(3HCDH)PF02737(3HCDH_N) | 5 | ALA A 50GLY A 20LEU A 39ASP A 41ILE A 16 | None | 1.17A | 3wdmD-4j0eA:4.2 | 3wdmD-4j0eA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kry | ACETYL ESTERASE (Escherichiacoli) |
PF07859(Abhydrolase_3) | 5 | GLY A 210LEU A 10LEU A 291ASP A 262LEU A 209 | None | 0.98A | 3wdmD-4kryA:undetectable | 3wdmD-4kryA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kyz | DESIGNED PROTEINOR327 (syntheticconstruct) |
no annotation | 5 | GLY A 160LEU A 36LEU A 74ASN A 77ILE A 40 | None | 1.11A | 3wdmD-4kyzA:undetectable | 3wdmD-4kyzA:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1g | PEPTIDOGLYCANN-ACETYLGLUCOSAMINEDEACETYLASE (Bacillus cereus) |
PF01522(Polysacc_deac_1) | 5 | ALA A 238LEU A 77LEU A 213ASN A 210ILE A 222 | None | 1.05A | 3wdmD-4l1gA:undetectable | 3wdmD-4l1gA:24.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4mb2 | PHOSPHOPANTOTHENATESYNTHETASE (Thermococcusonnurineus) |
PF02006(PPS_PS) | 10 | ALA A 36ARG A 39GLY A 40LEU A 83LEU A 161ASP A 181LEU A 182ASN A 183ASN A 199ILE A 200 | ATP A 301 (-3.3A)ATP A 301 (-3.2A)ATP A 301 (-3.4A)NoneATP A 301 (-3.9A)ATP A 301 (-2.7A)ATP A 301 (-3.8A)NoneATP A 301 (-3.0A)ATP A 301 (-4.3A) | 0.59A | 3wdmD-4mb2A:39.7 | 3wdmD-4mb2A:90.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1o | RIBONUCLEASE L (Sus scrofa) |
PF00069(Pkinase)PF06479(Ribonuc_2-5A)PF12796(Ank_2)PF13857(Ank_5) | 5 | ARG A 516LEU A 473LEU A 483LEU A 518ILE A 470 | None | 1.13A | 3wdmD-4o1oA:undetectable | 3wdmD-4o1oA:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6r | ALDEHYDEDEHYDROGENASE (Burkholderiacenocepacia) |
PF00171(Aldedh) | 5 | ALA A 40LEU A 5LEU A 44ASP A 47ILE A 7 | None | 1.15A | 3wdmD-4o6rA:undetectable | 3wdmD-4o6rA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o8v | ALGINATEBIOSYNTHESIS PROTEINALGJ (Pseudomonasputida) |
PF16822(ALGX) | 5 | ALA A 110ARG A 113GLY A 114LEU A 355ILE A 363 | None | 0.94A | 3wdmD-4o8vA:undetectable | 3wdmD-4o8vA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q2h | PROLINE RACEMASEPROTEIN (Agrobacteriumtumefaciens) |
PF05544(Pro_racemase) | 5 | ALA A 89LEU A 70LEU A 41LEU A 50ILE A 29 | None | 1.17A | 3wdmD-4q2hA:undetectable | 3wdmD-4q2hA:24.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qgr | DEGT/DNRJ/ERYC1/STRSAMINOTRANSFERASE (Brucellaabortus) |
PF01041(DegT_DnrJ_EryC1) | 5 | ALA A 178GLY A 183LEU A 43ASP A 137ILE A 167 | None | 1.07A | 3wdmD-4qgrA:2.1 | 3wdmD-4qgrA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6l | BACTERIOPHYTOCHROME(LIGHT-REGULATEDSIGNAL TRANSDUCTIONHISTIDINE KINASE),PHYB1 (Rhodopseudomonaspalustris) |
PF00360(PHY)PF01590(GAF)PF08446(PAS_2) | 5 | ALA A 328ARG A 331LEU A 357LEU A 333ASN A 335 | None | 1.10A | 3wdmD-4r6lA:undetectable | 3wdmD-4r6lA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tzh | LIC12234 (Leptospirainterrogans) |
PF13855(LRR_8) | 5 | GLY A 177LEU A 149LEU A 185LEU A 203ILE A 172 | None | 1.16A | 3wdmD-4tzhA:undetectable | 3wdmD-4tzhA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u9c | LACTOFERRIN-BINDINGPROTEIN B (Neisseriameningitidis) |
PF01298(TbpB_B_D)PF17484(TbpB_A) | 5 | ARG A 327GLY A 326LEU A 245LEU A 312ILE A 273 | None | 1.01A | 3wdmD-4u9cA:undetectable | 3wdmD-4u9cA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w7g | DYNEIN LIGHTINTERMEDIATE CHAIN (Chaetomiumthermophilum) |
PF05783(DLIC) | 5 | GLY A 288LEU A 282LEU A 139ASN A 137ILE A 283 | None | 1.09A | 3wdmD-4w7gA:undetectable | 3wdmD-4w7gA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z1a | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE (Helicobacterpylori) |
PF00793(DAHP_synth_1) | 5 | ALA A 30GLY A 16LEU A 73LEU A 26ILE A 20 | None | 1.09A | 3wdmD-4z1aA:undetectable | 3wdmD-4z1aA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z61 | PHYTOSULFOKINERECEPTOR 1 (Daucus carota) |
PF00560(LRR_1)PF13855(LRR_8) | 5 | ALA A 214GLY A 212LEU A 237LEU A 211ILE A 198 | None | 1.18A | 3wdmD-4z61A:undetectable | 3wdmD-4z61A:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z61 | PHYTOSULFOKINERECEPTOR 1 (Daucus carota) |
PF00560(LRR_1)PF13855(LRR_8) | 5 | ALA A 236LEU A 226LEU A 213ASN A 239ILE A 198 | None | 1.04A | 3wdmD-4z61A:undetectable | 3wdmD-4z61A:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zke | SUPERKILLER PROTEIN7 (Saccharomycescerevisiae) |
PF00009(GTP_EFTU) | 5 | GLY A 285LEU A 588ASP A 356LEU A 284ILE A 339 | GLY A 285 ( 0.0A)LEU A 588 ( 0.6A)ASP A 356 ( 0.6A)LEU A 284 ( 0.6A)ILE A 339 ( 0.4A) | 1.07A | 3wdmD-4zkeA:undetectable | 3wdmD-4zkeA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hfi | UNCHARACTERIZEDPROTEIN, CYTOSOLICDISULFIDE REDUCTASEDSBM (Pseudomonasaeruginosa) |
PF01323(DSBA) | 5 | ALA A 93LEU A 133ASP A 11LEU A 13ILE A 116 | ALA A 93 ( 0.0A)LEU A 133 ( 0.6A)ASP A 11 ( 0.5A)LEU A 13 ( 0.6A)ILE A 116 ( 0.7A) | 1.17A | 3wdmD-5hfiA:undetectable | 3wdmD-5hfiA:23.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) |
PF00067(p450) | 5 | ALA A 143LEU A 126LEU A 138ASP A 137ILE A 129 | None | 1.15A | 3wdmD-5it1A:undetectable | 3wdmD-5it1A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ixm | LPS-ASSEMBLYLIPOPROTEIN LPTE (Yersinia pestis) |
PF04390(LptE) | 5 | GLY B 59LEU B 135LEU B 28ASP B 23ILE B 32 | None | 1.13A | 3wdmD-5ixmB:undetectable | 3wdmD-5ixmB:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9w | ACETOPHENONECARBOXYLASE ALPHASUBUNIT (Aromatoleumaromaticum) |
PF01968(Hydantoinase_A)PF05378(Hydant_A_N) | 5 | ARG b 191GLY b 179LEU b 145LEU b 178ILE b 158 | None | 1.13A | 3wdmD-5l9wb:undetectable | 3wdmD-5l9wb:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mg5 | HYDROXYMETHYLGLUTARYL-COA SYNTHASE (Pseudomonasprotegens) |
no annotation | 6 | ALA A 175GLY A 7LEU A 122LEU A 313ASP A 178ILE A 311 | None | 1.25A | 3wdmD-5mg5A:undetectable | 3wdmD-5mg5A:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mjr | PROTEIN THF1 (Thermosynechococcuselongatus) |
PF11264(ThylakoidFormat) | 5 | ALA A 53GLY A 55LEU A 80LEU A 134ILE A 37 | None | 1.16A | 3wdmD-5mjrA:undetectable | 3wdmD-5mjrA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n1x | B-CELL LYMPHOMA 6PROTEIN (Homo sapiens) |
PF00651(BTB) | 5 | ALA D 109GLY D 82LEU D 97ASN D 101ILE D 102 | None | 1.12A | 3wdmD-5n1xD:undetectable | 3wdmD-5n1xD:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o6y | PEPTIDOGLYCANN-ACETYLGLUCOSAMINEDEACETYLASE (Bacillus cereus) |
no annotation | 5 | ALA B 238LEU B 77LEU B 213ASN B 210ILE B 222 | None | 1.10A | 3wdmD-5o6yB:undetectable | 3wdmD-5o6yB:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ve8 | KAP123 (Kluyveromyceslactis) |
no annotation | 5 | ALA A 848LEU A 800LEU A 780LEU A 853ILE A 788 | None | 1.04A | 3wdmD-5ve8A:undetectable | 3wdmD-5ve8A:13.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y6t | ENDO-1,4-BETA-MANNANASE (Eisenia fetida) |
no annotation | 5 | ALA A 170GLY A 172LEU A 376LEU A 20ILE A 374 | None | 1.01A | 3wdmD-5y6tA:undetectable | 3wdmD-5y6tA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z06 | BDI_3064 PROTEIN (Parabacteroidesdistasonis) |
no annotation | 5 | ALA A 116ARG A 138LEU A 137ASN A 136ILE A 189 | None | 1.07A | 3wdmD-5z06A:undetectable | 3wdmD-5z06A:11.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b5e | GLUCOSE-1-PHOSPHATETHYMIDYLYLTRANSFERASE (Mycobacteriumtuberculosis) |
no annotation | 5 | GLY A 171LEU A 41ASP A 108LEU A 106ILE A 5 | DAU A 301 ( 4.3A)None MG A 302 ( 2.5A)DAU A 301 (-3.9A)None | 1.12A | 3wdmD-6b5eA:undetectable | 3wdmD-6b5eA:11.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c0d | AMIDASE,HYDANTOINASE/CARBAMOYLASE FAMILY (Paraburkholderiaphymatum) |
no annotation | 5 | ALA A 162LEU A 134LEU A 35LEU A 168ILE A 124 | None | 1.05A | 3wdmD-6c0dA:undetectable | 3wdmD-6c0dA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d6u | GAMMA-AMINOBUTYRICACID RECEPTORSUBUNITALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTORSUBUNIT ALPHA-1 (Homo sapiens) |
no annotation | 5 | ALA B 91LEU B 75LEU B 119ASN B 87ILE B 121 | None | 1.06A | 3wdmD-6d6uB:undetectable | 3wdmD-6d6uB:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f85 | CYTOCHROME P450CYP260A1 (Sorangiumcellulosum) |
no annotation | 5 | ALA A 177ARG A 176GLY A 179LEU A 224ILE A 185 | None | 1.18A | 3wdmD-6f85A:undetectable | 3wdmD-6f85A:13.16 |