SIMILAR PATTERNS OF AMINO ACIDS FOR 3W9T_G_W9TG501

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)

Filter list by:

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1vcl	HEMOLYTIC LECTIN CEL-III (Cucumaria echinata)	PF00652 (Ricin_B_lectin)	4	ASP A 256 GLY A 259 TRP A 269 ASP A 272	CA A1005 (-2.7A) CA A1005 (-4.3A) None CA A1005 ( 4.8A)	0.49A	3w9tG-1vclA: 36.9	3w9tG-1vclA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ecq	ENDO-ALPHA-N-ACETYLG ALACTOSAMINIDASE (Streptococcus pneumoniae)	PF12905 (Glyco_hydro_101) PF17451 (Glyco_hyd_101C)	4	ASP A 585 GLY A 589 TRP A 586 ASP A 468	CA A2000 ( 4.6A) None None None	1.20A	3w9tG-3ecqA: 0.0	3w9tG-3ecqA: 14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5a55	ENDO-ALPHA-N-ACETYLG ALACTOSAMINIDASE (Streptococcus pneumoniae)	PF12905 (Glyco_hydro_101) PF17451 (Glyco_hyd_101C)	4	ASP A 585 GLY A 589 TRP A 586 ASP A 468	CA A2419 ( 4.7A) None None None	1.29A	3w9tG-5a55A: 0.0	3w9tG-5a55A: 17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5xjy	ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 1 (Homo sapiens)	PF00005 (ABC_tran) PF12698 (ABC2_membrane_3)	4	ASP A 575 GLY A 577 TRP A 574 ASP A 571	None	1.19A	3w9tG-5xjyA: 0.0	3w9tG-5xjyA: 11.25

[["3W9T_G_W9TG501_1","1vcl","Cucumaria echinata","HEMOLYTIC LECTIN CEL-III","PF00652(Ricin_B_lectin)",4,"ASP A 256;GLY A 259;TRP A 269;ASP A 272"," CA A1005 (-2.7A); CA A1005 (-4.3A);None; CA A1005 ( 4.8A)","0.49A","3w9tG-1vclA:36.9","3w9tG-1vclA:100.00"],["3W9T_G_W9TG501_1","3ecq","Streptococcus pneumoniae","ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE","PF12905(Glyco_hydro_101);PF17451(Glyco_hyd_101C)",4,"ASP A 585;GLY A 589;TRP A 586;ASP A 468"," CA A2000 ( 4.6A);None;None;None","1.20A","3w9tG-3ecqA:0.0","3w9tG-3ecqA:14.47"],["3W9T_G_W9TG501_1","5a55","Streptococcus pneumoniae","ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE","PF12905(Glyco_hydro_101);PF17451(Glyco_hyd_101C)",4,"ASP A 585;GLY A 589;TRP A 586;ASP A 468"," CA A2419 ( 4.7A);None;None;None","1.29A","3w9tG-5a55A:0.0","3w9tG-5a55A:17.44"],["3W9T_G_W9TG501_1","5xjy","Homo sapiens","ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 1","PF00005(ABC_tran);PF12698(ABC2_membrane_3)",4,"ASP A 575;GLY A 577;TRP A 574;ASP A 571","None","1.19A","3w9tG-5xjyA:0.0","3w9tG-5xjyA:11.25"]]