SIMILAR PATTERNS OF AMINO ACIDS FOR 3W9T_F_W9TF512

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3j NADP(H)-DEPENDENT
KETOSE REDUCTASE


(Bemisia
argentifolii)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 CYH A  41
GLY A  42
ASP A  44
ILE A  64
ZN  A 902 (-2.4A)
None
None
None
1.00A 3w9tF-1e3jA:
0.0
3w9tF-1e3jA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ept PORCINE E-TRYPSIN

(Sus scrofa)
PF00089
(Trypsin)
4 THR B 144
ASN B 143
GLY C 193
ILE B  73
None
0.85A 3w9tF-1eptB:
undetectable
3w9tF-1eptB:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eqc EXO-(B)-(1,3)-GLUCAN
ASE


(Candida
albicans)
PF00150
(Cellulase)
4 THR A 377
ASN A 381
GLY A 382
ILE A 347
None
0.74A 3w9tF-1eqcA:
undetectable
3w9tF-1eqcA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h9h TRYPSIN

(Sus scrofa)
PF00089
(Trypsin)
4 THR E 144
ASN E 143
GLY E 193
ILE E  73
None
0.80A 3w9tF-1h9hE:
0.0
3w9tF-1h9hE:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j17 TRYPSIN II, ANIONIC

(Rattus
norvegicus)
PF00089
(Trypsin)
4 THR T 144
ASN T 143
GLY T 193
ILE T  73
None
None
SO4  T 600 (-3.8A)
None
0.80A 3w9tF-1j17T:
0.0
3w9tF-1j17T:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ksi COPPER AMINE OXIDASE

(Pisum sativum)
PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3)
4 ASN A 386
GLY A 409
ASP A 388
ILE A 381
TPQ  A 387 ( 3.1A)
TPQ  A 387 ( 4.9A)
TPQ  A 387 ( 3.9A)
None
0.87A 3w9tF-1ksiA:
0.0
3w9tF-1ksiA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5j ACONITATE HYDRATASE
2


(Escherichia
coli)
PF00330
(Aconitase)
PF06434
(Aconitase_2_N)
PF11791
(Aconitase_B_N)
4 THR A 445
CYH A 769
GLY A 768
ILE A 479
None
F3S  A 868 (-2.2A)
None
None
1.02A 3w9tF-1l5jA:
0.0
3w9tF-1l5jA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m6s L-ALLO-THREONINE
ALDOLASE


(Thermotoga
maritima)
PF01212
(Beta_elim_lyase)
4 ASN A 136
GLY A 169
ASP A 168
ILE A  84
None
None
LLP  A 199 ( 2.8A)
None
0.99A 3w9tF-1m6sA:
0.0
3w9tF-1m6sA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nxb NEUROTOXIN B

(Laticauda
semifasciata)
PF00087
(Toxin_TOLIP)
4 THR A  13
ASN A   5
GLY A  40
ILE A  37
None
SO4  A  64 (-4.1A)
None
None
0.98A 3w9tF-1nxbA:
undetectable
3w9tF-1nxbA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oqk CONSERVED PROTEIN
MTH11


(Methanothermobacter
thermautotrophicus)
PF01868
(UPF0086)
4 THR A  38
ASN A  40
GLY A  57
ILE A  27
None
0.99A 3w9tF-1oqkA:
undetectable
3w9tF-1oqkA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qil TOXIC SHOCK SYNDROME
TOXIN-1


(Staphylococcus
aureus)
PF02876
(Stap_Strp_tox_C)
4 THR A  19
ASN A  65
GLY A  87
ILE A  35
None
1.04A 3w9tF-1qilA:
undetectable
3w9tF-1qilA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qye ENDOPLASMIN

(Canis lupus)
PF00183
(HSP90)
PF02518
(HATPase_c)
4 ASN A 239
GLY A 238
ASP A 235
ILE A 222
None
0.67A 3w9tF-1qyeA:
undetectable
3w9tF-1qyeA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)


(Rhinovirus A)
PF00073
(Rhv)
4 THR 1 205
ASN 1 204
GLY 1 202
ASP 1 203
None
1.04A 3w9tF-1r1a1:
undetectable
3w9tF-1r1a1:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rdr POLIOVIRUS 3D
POLYMERASE


(Enterovirus C)
PF00680
(RdRP_1)
4 THR A 293
ASN A 297
GLY A 327
ILE A  17
None
0.98A 3w9tF-1rdrA:
undetectable
3w9tF-1rdrA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t0p INTEGRIN ALPHA-L

(Homo sapiens)
PF00092
(VWA)
4 THR A 243
ASN A 207
GLY A 210
ILE A 236
None
0.90A 3w9tF-1t0pA:
undetectable
3w9tF-1t0pA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1urx BETA-AGARASE A

(Zobellia
galactanivorans)
PF00722
(Glyco_hydro_16)
4 THR A  79
ASN A 107
GLY A 108
ILE A 250
None
1.01A 3w9tF-1urxA:
undetectable
3w9tF-1urxA:
19.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1vcl HEMOLYTIC LECTIN
CEL-III


(Cucumaria
echinata)
PF00652
(Ricin_B_lectin)
4 THR A   5
GLY A  50
ASP A  51
ILE A  84
None
None
PCA  A   1 ( 4.6A)
PCA  A   1 ( 4.9A)
0.44A 3w9tF-1vclA:
36.7
3w9tF-1vclA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w9w BH0236 PROTEIN

(Bacillus
halodurans)
PF03422
(CBM_6)
4 THR A  96
ASN A  95
GLY A  73
ILE A  43
None
BGC  A 605 ( 3.4A)
None
None
1.04A 3w9tF-1w9wA:
undetectable
3w9tF-1w9wA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aaf ARGININE DEIMINASE

(Pseudomonas
aeruginosa)
PF02274
(Amidinotransf)
4 THR A 281
ASN A 360
GLY A 358
ASP A 357
None
CYR  A 406 ( 3.0A)
None
None
0.83A 3w9tF-2aafA:
undetectable
3w9tF-2aafA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1


(Homo sapiens)
PF03178
(CPSF_A)
PF10433
(MMS1_N)
4 THR A 657
ASN A 670
GLY A 393
ILE A 707
None
0.97A 3w9tF-2b5mA:
undetectable
3w9tF-2b5mA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2y METHYLENETETRAHYDROF
OLATE
DEHYDROGENASE-METHEN
YLTETRAHYDROFOLATE
CYCLOHYDROLASE


(Mycobacterium
tuberculosis)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
4 THR A 141
GLY A 121
ASP A 120
ILE A  95
None
1.03A 3w9tF-2c2yA:
undetectable
3w9tF-2c2yA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2y METHYLENETETRAHYDROF
OLATE
DEHYDROGENASE-METHEN
YLTETRAHYDROFOLATE
CYCLOHYDROLASE


(Mycobacterium
tuberculosis)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
4 THR A 169
GLY A 121
ASP A 120
ILE A  95
None
0.91A 3w9tF-2c2yA:
undetectable
3w9tF-2c2yA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cev PROTEIN (ARGINASE)

([Bacillus]
caldovelox)
PF00491
(Arginase)
4 THR A 129
ASN A 128
GLY A 140
ILE A 103
None
1.03A 3w9tF-2cevA:
undetectable
3w9tF-2cevA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cnd NADH-DEPENDENT
NITRATE REDUCTASE


(Zea mays)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6)
4 THR A 149
CYH A 143
GLY A 144
ILE A 181
FAD  A 271 (-2.7A)
None
None
None
1.01A 3w9tF-2cndA:
undetectable
3w9tF-2cndA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7z ACETYLENE HYDRATASE
AHY


(Pelobacter
acetylenicus)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
4 THR A 269
GLY A 219
ASP A 221
ILE A 170
None
MGD  A 802 (-3.5A)
MGD  A 802 (-2.7A)
MGD  A 802 (-4.7A)
0.86A 3w9tF-2e7zA:
undetectable
3w9tF-2e7zA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2erq VASCULAR
APOPTOSIS-INDUCING
PROTEIN 1


(Crotalus atrox)
PF00200
(Disintegrin)
PF01421
(Reprolysin)
PF08516
(ADAM_CR)
4 THR A 312
ASN A 311
GLY A 308
ILE A 391
None
0.91A 3w9tF-2erqA:
undetectable
3w9tF-2erqA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix8 ELONGATION FACTOR 3A

(Saccharomyces
cerevisiae)
PF00005
(ABC_tran)
4 THR A1133
ASN A1134
CYH A1095
ILE A1116
None
0.91A 3w9tF-2ix8A:
undetectable
3w9tF-2ix8A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kks UNCHARACTERIZED
PROTEIN


(Desulfitobacterium
hafniense)
PF14464
(Prok-JAB)
4 ASN A  79
CYH A  25
GLY A  26
ASP A  58
None
0.98A 3w9tF-2kksA:
undetectable
3w9tF-2kksA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1v ENDOPLASMIN

(Canis lupus)
PF00183
(HSP90)
PF02518
(HATPase_c)
4 ASN A 239
GLY A 238
ASP A 235
ILE A 222
None
0.70A 3w9tF-2o1vA:
undetectable
3w9tF-2o1vA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1w ENDOPLASMIN

(Canis lupus)
PF00183
(HSP90)
PF02518
(HATPase_c)
4 ASN A 239
GLY A 238
ASP A 235
ILE A 222
None
0.63A 3w9tF-2o1wA:
undetectable
3w9tF-2o1wA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w9x PUTATIVE ACETYL
XYLAN ESTERASE


(Cellvibrio
japonicus)
PF00657
(Lipase_GDSL)
4 THR A 246
ASN A 247
GLY A 201
ILE A 242
None
GOL  A1362 ( 4.6A)
None
None
0.81A 3w9tF-2w9xA:
undetectable
3w9tF-2w9xA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzj 167AA LONG
HYPOTHETICAL DUTPASE


(Sulfurisphaera
tokodaii)
PF00692
(dUTPase)
4 THR A 102
ASN A 106
GLY A 107
ILE A 127
None
0.79A 3w9tF-2yzjA:
undetectable
3w9tF-2yzjA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agf GLUTAMINASE 1

(Bacillus
subtilis)
PF04960
(Glutaminase)
4 ASN A 254
GLY A 103
ASP A 104
ILE A 110
None
0.91A 3w9tF-3agfA:
undetectable
3w9tF-3agfA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aib GLUCOSYLTRANSFERASE-
SI


(Streptococcus
mutans)
PF02324
(Glyco_hydro_70)
4 THR A1051
ASN A1052
GLY A 385
ILE A 987
None
0.90A 3w9tF-3aibA:
undetectable
3w9tF-3aibA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce6 ADENOSYLHOMOCYSTEINA
SE


(Mycobacterium
tuberculosis)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
4 THR A 257
ASN A 409
GLY A 264
ILE A 333
None
NAD  A 550 (-3.0A)
None
None
0.85A 3w9tF-3ce6A:
undetectable
3w9tF-3ce6A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d46 PUTATIVE GALACTONATE
DEHYDRATASE


(Salmonella
enterica)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 THR A  87
ASN A 135
GLY A 304
ASP A 302
None
1.02A 3w9tF-3d46A:
undetectable
3w9tF-3d46A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e9z PURINE-NUCLEOSIDE
PHOSPHORYLASE


(Schistosoma
mansoni)
PF01048
(PNP_UDP_1)
4 THR A 223
ASN A 117
GLY A  34
ILE A  31
None
None
SO4  A 291 (-3.0A)
None
1.02A 3w9tF-3e9zA:
undetectable
3w9tF-3e9zA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eh2 PROTEIN TRANSPORT
PROTEIN SEC24C


(Homo sapiens)
PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS)
4 ASN A 473
CYH A 504
GLY A 477
ILE A 434
None
0.98A 3w9tF-3eh2A:
undetectable
3w9tF-3eh2A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gq9 PRENECK APPENDAGE
PROTEIN


(Bacillus virus
phi29)
PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3)
4 THR A 432
ASN A 458
GLY A 486
ILE A 474
None
0.95A 3w9tF-3gq9A:
undetectable
3w9tF-3gq9A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h3l PUTATIVE SUGAR
HYDROLASE


(Parabacteroides
distasonis)
PF06439
(DUF1080)
4 THR A  60
ASN A  62
GLY A  63
ILE A 265
None
1.03A 3w9tF-3h3lA:
undetectable
3w9tF-3h3lA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN


(Pseudomonas
protegens)
PF13407
(Peripla_BP_4)
4 THR A  63
ASN A  61
GLY A  60
ILE A  87
None
1.04A 3w9tF-3h75A:
undetectable
3w9tF-3h75A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h8t HMUY

(Porphyromonas
gingivalis)
PF14064
(HmuY)
4 THR A 116
CYH A  86
GLY A  87
ASP A 118
None
0.62A 3w9tF-3h8tA:
undetectable
3w9tF-3h8tA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jr7 UNCHARACTERIZED EGV
FAMILY PROTEIN
COG1307


([Ruminococcus]
gnavus)
PF02645
(DegV)
4 THR A 185
ASN A 189
GLY A 190
ILE A 217
None
0.78A 3w9tF-3jr7A:
undetectable
3w9tF-3jr7A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khs PURINE NUCLEOSIDE
PHOSPHORYLASE


(Singapore
grouper
iridovirus)
PF01048
(PNP_UDP_1)
4 THR A 218
ASN A 112
GLY A  29
ILE A  26
None
PO4  A 290 (-4.9A)
PO4  A 290 (-3.5A)
None
0.99A 3w9tF-3khsA:
undetectable
3w9tF-3khsA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyh MRNA-CAPPING ENZYME
SUBUNIT BETA


(Saccharomyces
cerevisiae)
PF02940
(mRNA_triPase)
4 THR A 522
ASN A 525
GLY A 527
ILE A 470
None
1.04A 3w9tF-3kyhA:
undetectable
3w9tF-3kyhA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyh MRNA-CAPPING ENZYME
SUBUNIT BETA


(Saccharomyces
cerevisiae)
PF02940
(mRNA_triPase)
4 THR A 522
ASN A 526
GLY A 527
ILE A 428
None
0.89A 3w9tF-3kyhA:
undetectable
3w9tF-3kyhA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lml LIN1278 PROTEIN

(Listeria
innocua)
PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N)
PF17482
(Phage_sheath_1C)
4 THR A 365
ASN A 362
GLY A 360
ILE A 410
None
1.00A 3w9tF-3lmlA:
undetectable
3w9tF-3lmlA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nv9 MALIC ENZYME

(Entamoeba
histolytica)
PF00390
(malic)
PF03949
(Malic_M)
4 THR A 198
ASN A 359
GLY A 362
ILE A 405
None
GOL  A 497 (-3.3A)
None
None
0.91A 3w9tF-3nv9A:
undetectable
3w9tF-3nv9A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozi L6TR

(Linum
usitatissimum)
PF01582
(TIR)
4 ASN A 182
GLY A 180
ASP A 183
ILE A 188
None
0.95A 3w9tF-3oziA:
undetectable
3w9tF-3oziA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qjg EPIDERMIN
BIOSYNTHESIS PROTEIN
EPID


(Staphylococcus
aureus)
PF02441
(Flavoprotein)
4 THR A  38
ASN A  39
GLY A  11
ILE A  79
None
FMN  A 501 (-3.8A)
FMN  A 501 (-3.6A)
None
0.84A 3w9tF-3qjgA:
undetectable
3w9tF-3qjgA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suc PRENECK APPENDAGE
PROTEIN


(Bacillus virus
phi29)
PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3)
4 THR A 432
ASN A 458
GLY A 486
ILE A 474
None
0.97A 3w9tF-3sucA:
undetectable
3w9tF-3sucA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tov GLYCOSYL TRANSFERASE
FAMILY 9


(Veillonella
parvula)
PF01075
(Glyco_transf_9)
4 THR A  11
ASN A  92
GLY A 113
ILE A 110
None
1.01A 3w9tF-3tovA:
undetectable
3w9tF-3tovA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tpf ORNITHINE
CARBAMOYLTRANSFERASE


(Campylobacter
jejuni)
PF00185
(OTCace)
PF02729
(OTCace_N)
4 ASN A 287
GLY A 130
ASP A 131
ILE A 218
None
0.71A 3w9tF-3tpfA:
undetectable
3w9tF-3tpfA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u37 ACETYL-XYLAN
ESTERASE EST2A


(Butyrivibrio
proteoclasticus)
PF13472
(Lipase_GDSL_2)
4 THR A 342
ASN A 345
GLY A 353
ILE A 143
None
0.99A 3w9tF-3u37A:
undetectable
3w9tF-3u37A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3via PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY B MEMBER 2


(Homo sapiens)
PF00169
(PH)
4 THR A 111
ASN A 112
GLY A  32
ILE A  81
None
1.03A 3w9tF-3viaA:
1.1
3w9tF-3viaA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wcq FERREDOXIN

(Cyanidioschyzon
merolae)
PF00111
(Fer2)
4 THR A  83
CYH A  86
GLY A  55
ILE A  75
None
0.78A 3w9tF-3wcqA:
undetectable
3w9tF-3wcqA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3u NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE


(Zymomonas
mobilis)
PF00724
(Oxidored_FMN)
4 ASN A 175
GLY A 176
ASP A 180
ILE A 183
NCA  A1359 ( 3.3A)
None
None
None
0.94A 3w9tF-4a3uA:
undetectable
3w9tF-4a3uA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amc GLUCANSUCRASE

(Lactobacillus
reuteri)
PF01473
(CW_binding_1)
PF02324
(Glyco_hydro_70)
4 THR A1604
ASN A1605
GLY A 942
ILE A1541
None
1.04A 3w9tF-4amcA:
undetectable
3w9tF-4amcA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amf PHOX

(Pseudomonas
fluorescens)
PF05787
(DUF839)
4 THR A 493
ASN A 509
GLY A 527
ILE A  16
None
0.81A 3w9tF-4amfA:
undetectable
3w9tF-4amfA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ayg GLUCANSUCRASE

(Lactobacillus
reuteri)
PF01473
(CW_binding_1)
PF02324
(Glyco_hydro_70)
4 THR A1599
ASN A1600
GLY A 943
ILE A1536
None
0.94A 3w9tF-4aygA:
undetectable
3w9tF-4aygA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b4c CHROMODOMAIN-HELICAS
E-DNA-BINDING
PROTEIN 1


(Homo sapiens)
no annotation 4 ASN A1174
CYH A1176
GLY A1175
ILE A1135
None
1.04A 3w9tF-4b4cA:
undetectable
3w9tF-4b4cA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4efi 3-OXOACYL-(ACYL-CARR
IER PROTEIN)
SYNTHASE


(Paraburkholderia
xenovorans)
PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III)
4 CYH A 307
GLY A 158
ASP A 159
ILE A 161
None
0.99A 3w9tF-4efiA:
undetectable
3w9tF-4efiA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ew9 PECTATE LYASE

(Caldicellulosiruptor
bescii)
PF03211
(Pectate_lyase)
4 THR A   0
ASN A   1
GLY A  22
ASP A  21
None
MPD  A 207 (-4.7A)
None
None
0.82A 3w9tF-4ew9A:
undetectable
3w9tF-4ew9A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h0p ACETATE KINASE

(Cryptococcus
neoformans)
PF00871
(Acetate_kinase)
4 THR A  37
ASN A  38
GLY A  67
ILE A  78
None
1.03A 3w9tF-4h0pA:
undetectable
3w9tF-4h0pA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lna PURINE NUCLEOSIDE
PHOSPHORYLASE


(Spirosoma
linguale)
PF01048
(PNP_UDP_1)
4 THR A 212
ASN A 110
GLY A  27
ILE A  24
None
None
PO4  A 500 (-3.3A)
None
1.04A 3w9tF-4lnaA:
undetectable
3w9tF-4lnaA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0q LEU/ILE/VAL-BINDING
PROTEIN HOMOLOG 3


(Brucella
melitensis)
PF13458
(Peripla_BP_6)
4 THR A  34
GLY A  75
ASP A  73
ILE A  30
None
0.94A 3w9tF-4n0qA:
undetectable
3w9tF-4n0qA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nf8 GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1


(Rattus
norvegicus)
PF10613
(Lig_chan-Glu_bd)
4 THR A  94
ASN A 107
GLY A 111
ILE A 121
None
0.88A 3w9tF-4nf8A:
undetectable
3w9tF-4nf8A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nv0 7-METHYLGUANOSINE
PHOSPHATE-SPECIFIC
5'-NUCLEOTIDASE


(Drosophila
melanogaster)
PF05822
(UMPH-1)
4 THR A 167
ASN A 191
GLY A 164
ILE A 303
None
0.95A 3w9tF-4nv0A:
undetectable
3w9tF-4nv0A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ohj TOXIC SHOCK SYNDROME
TOXIN-1


(Staphylococcus
aureus)
PF02876
(Stap_Strp_tox_C)
4 THR A  59
ASN A 105
GLY A 127
ILE A  75
None
1.03A 3w9tF-4ohjA:
undetectable
3w9tF-4ohjA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0d TRYPSIN-RESISTANT
SURFACE T6 PROTEIN


(Streptococcus
pyogenes)
PF16569
(GramPos_pilinBB)
4 THR A 320
ASN A  95
GLY A  96
ILE A  57
None
0.96A 3w9tF-4p0dA:
undetectable
3w9tF-4p0dA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q3i OSSERK2 D128N

(Oryza sativa)
PF08263
(LRRNT_2)
PF11921
(DUF3439)
4 THR A 167
ASN A 168
GLY A 143
ILE A 138
None
1.02A 3w9tF-4q3iA:
undetectable
3w9tF-4q3iA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qww ACETYLCHOLINESTERASE

(Bungarus
fasciatus)
PF00135
(COesterase)
4 THR A 483
ASN A 481
GLY A 480
ILE A 223
None
0.79A 3w9tF-4qwwA:
undetectable
3w9tF-4qwwA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uc0 PURINE NUCLEOSIDE
PHOSPHORYLASE


(Agrobacterium
vitis)
PF01048
(PNP_UDP_1)
4 THR A 205
ASN A 107
GLY A  24
ILE A  21
None
1.04A 3w9tF-4uc0A:
undetectable
3w9tF-4uc0A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uir OLEATE HYDRATASE

(Elizabethkingia
meningoseptica)
PF06100
(MCRA)
4 THR A 271
GLY A 102
ASP A 101
ILE A 284
None
0.83A 3w9tF-4uirA:
undetectable
3w9tF-4uirA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)


(Chaetomium)
PF13472
(Lipase_GDSL_2)
4 THR A 237
ASN A 238
GLY A 188
ILE A 233
None
PEU  A 402 (-2.8A)
None
None
0.86A 3w9tF-4xvhA:
undetectable
3w9tF-4xvhA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ye4 HT593.1 GP120
LIGHT CHAIN OF HJ16


(Homo sapiens;
Human
immunodeficiency
virus)
PF00516
(GP120)
PF07654
(C1-set)
PF07686
(V-set)
4 THR L 101
ASN G 462
GLY G 466
ILE G 469
None
0.99A 3w9tF-4ye4L:
undetectable
3w9tF-4ye4L:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yji ARYL ACYLAMIDASE

(bacterium
CSBL00001)
PF01425
(Amidase)
4 THR A 150
ASN A  46
GLY A  44
ILE A 175
None
0.92A 3w9tF-4yjiA:
undetectable
3w9tF-4yjiA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5axh DEXTRANASE

(Thermoanaerobacter
pseudethanolicus)
PF13199
(Glyco_hydro_66)
4 THR A 353
ASN A 352
GLY A 312
ILE A 349
None
GLC  A 704 ( 3.8A)
GLC  A 704 ( 3.9A)
None
0.94A 3w9tF-5axhA:
undetectable
3w9tF-5axhA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b5z PTLCIB4 H88A MUTANT

(Phaeodactylum
tricornutum)
no annotation 4 THR A  39
ASN A  38
GLY A  92
ILE A 219
None
0.82A 3w9tF-5b5zA:
undetectable
3w9tF-5b5zA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bza BETA-N-ACETYLHEXOSAM
INIDASE


(Thermotoga
neapolitana)
PF00933
(Glyco_hydro_3)
4 ASN A 277
CYH A  11
GLY A  12
ILE A  24
None
0.98A 3w9tF-5bzaA:
undetectable
3w9tF-5bzaA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e6s INTEGRIN ALPHA-L

(Homo sapiens)
PF00092
(VWA)
PF01839
(FG-GAP)
PF08441
(Integrin_alpha2)
4 THR A 243
ASN A 207
GLY A 210
ILE A 236
None
0.88A 3w9tF-5e6sA:
undetectable
3w9tF-5e6sA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ebb ACID
SPHINGOMYELINASE-LIK
E PHOSPHODIESTERASE
3A


(Homo sapiens)
PF00149
(Metallophos)
4 ASN A 151
GLY A 150
ASP A 153
ILE A 129
MLI  A 706 ( 2.6A)
None
None
None
1.04A 3w9tF-5ebbA:
undetectable
3w9tF-5ebbA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g4l OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN


(Clostridium sp.)
PF13561
(adh_short_C2)
4 THR A 153
GLY A 103
ASP A 125
ILE A 121
None
NDP  A1265 (-3.3A)
NDP  A1265 ( 4.8A)
None
1.01A 3w9tF-5g4lA:
undetectable
3w9tF-5g4lA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h4s L-RHAMNOSE-BINDING
LECTIN


(Toxopneustes
pileolus)
PF02140
(Gal_Lectin)
4 THR A 273
ASN A 232
GLY A 231
ILE A 228
None
0.86A 3w9tF-5h4sA:
undetectable
3w9tF-5h4sA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2


(Saccharomyces
cerevisiae)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
4 ASN B 538
CYH B 523
GLY B 750
ILE B 756
None
1.03A 3w9tF-5ip9B:
undetectable
3w9tF-5ip9B:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k10 ISOCITRATE
DEHYDROGENASE [NADP]
CYTOPLASMIC


(Homo sapiens)
PF00180
(Iso_dh)
4 THR A  98
ASN A 101
GLY A 104
ILE A  64
None
1.02A 3w9tF-5k10A:
undetectable
3w9tF-5k10A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kdi PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY A MEMBER 8


(Homo sapiens)
no annotation 4 THR A 420
ASN A 424
GLY A 425
ILE A 429
None
1.04A 3w9tF-5kdiA:
undetectable
3w9tF-5kdiA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ko5 PURINE NUCLEOSIDE
PHOSPHORYLASE


(Schistosoma
mansoni)
PF01048
(PNP_UDP_1)
4 THR A 223
ASN A 117
GLY A  34
ILE A  31
None
None
EDO  A 302 (-3.4A)
None
0.98A 3w9tF-5ko5A:
undetectable
3w9tF-5ko5A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lwg VP3
VP4


(Israeli acute
paralysis virus)
PF11492
(Dicistro_VP4)
no annotation
4 THR D  50
GLY C  41
ASP C  42
ILE D  42
None
0.86A 3w9tF-5lwgD:
undetectable
3w9tF-5lwgD:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vm9 PROTEIN ARGONAUTE-3

(Homo sapiens)
no annotation 4 THR A 600
GLY A 671
ASP A 670
ILE A 800
None
0.98A 3w9tF-5vm9A:
undetectable
3w9tF-5vm9A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wea PROTEIN ARGONAUTE-2

(Homo sapiens)
no annotation 4 THR A 599
GLY A 670
ASP A 669
ILE A 799
None
0.74A 3w9tF-5weaA:
undetectable
3w9tF-5weaA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x04 DODECANOYL-[ACYL-CAR
RIER-PROTEIN]
HYDROLASE,
CHLOROPLASTIC


(Umbellularia
californica)
no annotation 4 THR A 231
ASN A 195
GLY A 196
ILE A 240
None
0.90A 3w9tF-5x04A:
undetectable
3w9tF-5x04A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y1a -

(-)
no annotation 4 THR A 193
GLY A 197
ASP A 198
ILE A 210
None
0.97A 3w9tF-5y1aA:
undetectable
3w9tF-5y1aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ydj ACETYLCHOLINESTERASE

(Anopheles
gambiae)
no annotation 4 THR A 390
ASN A 563
GLY A 387
ILE A 478
None
None
SEB  A 360 ( 4.0A)
None
0.90A 3w9tF-5ydjA:
undetectable
3w9tF-5ydjA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aom ENDOPLASMIN

(Canis lupus)
no annotation 4 ASN A 239
GLY A 238
ASP A 235
ILE A 222
None
0.70A 3w9tF-6aomA:
undetectable
3w9tF-6aomA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6arx ACETYLCHOLINESTERASE

(Anopheles
gambiae)
no annotation 4 THR A 390
ASN A 563
GLY A 387
ILE A 478
None
0.96A 3w9tF-6arxA:
undetectable
3w9tF-6arxA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC2


(Saccharomyces
cerevisiae)
no annotation 4 THR B 439
ASN B 441
GLY B 453
ILE B 194
None
1.04A 3w9tF-6f42B:
undetectable
3w9tF-6f42B:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fg8 SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 1


(Arabidopsis
thaliana)
no annotation 4 THR A 162
ASN A 163
GLY A 138
ILE A 133
NAG  A 308 (-3.8A)
NAG  A 310 ( 1.8A)
None
None
1.00A 3w9tF-6fg8A:
undetectable
3w9tF-6fg8A:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g1o -

(-)
no annotation 4 THR A 340
ASN A 344
GLY A 345
ILE A 212
None
0.90A 3w9tF-6g1oA:
undetectable
3w9tF-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g42 MINOR CAPSID PROTEIN

(Cafeteriavirus-dependent
mavirus)
no annotation 4 THR A 143
ASN A 145
GLY A 149
ILE A  73
None
0.92A 3w9tF-6g42A:
undetectable
3w9tF-6g42A:
12.43