SIMILAR PATTERNS OF AMINO ACIDS FOR 3W9T_E_W9TE506

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a4i METHYLENETETRAHYDROF
OLATE DEHYDROGENASE
/
METHENYLTETRAHYDROFO
LATE CYCLOHYDROLASE


(Homo sapiens)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
4 CYH A 147
THR A 148
GLY A 126
ASP A 125
None
NDP  A 302 (-3.6A)
None
None
1.19A 3w9tE-1a4iA:
0.0
3w9tE-1a4iA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b0a PROTEIN (FOLD
BIFUNCTIONAL
PROTEIN)


(Escherichia
coli)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
4 CYH A 141
THR A 142
GLY A 122
ASP A 121
None
1.22A 3w9tE-1b0aA:
0.0
3w9tE-1b0aA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)


(Escherichia
coli)
PF01053
(Cys_Met_Meta_PP)
4 THR A  75
ASN A  74
GLY A 234
ASP A 237
LLP  A 198 ( 4.0A)
None
None
None
1.24A 3w9tE-1cs1A:
0.0
3w9tE-1cs1A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1csj HEPATITIS C VIRUS
RNA POLYMERASE
(NS5B)


(Hepacivirus C)
PF00998
(RdRP_3)
4 CYH A 295
THR A 294
ASN A 291
GLY A 317
None
1.25A 3w9tE-1csjA:
0.0
3w9tE-1csjA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cvr GINGIPAIN R

(Porphyromonas
gingivalis)
PF01364
(Peptidase_C25)
PF03785
(Peptidase_C25_C)
4 CYH A 255
ASN A 246
GLY A 247
ASP A 248
None
1.11A 3w9tE-1cvrA:
0.0
3w9tE-1cvrA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cvr GINGIPAIN R

(Porphyromonas
gingivalis)
PF01364
(Peptidase_C25)
PF03785
(Peptidase_C25_C)
4 CYH A 255
THR A 215
GLY A 247
ASP A 248
None
1.15A 3w9tE-1cvrA:
0.0
3w9tE-1cvrA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6w SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE


(Rattus
norvegicus)
PF00106
(adh_short)
4 CYH A  58
THR A  36
ASN A  57
GLY A  55
None
1.20A 3w9tE-1e6wA:
0.0
3w9tE-1e6wA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e9m FERREDOXIN VI

(Rhodobacter
capsulatus)
PF00111
(Fer2)
4 CYH A  48
THR A  47
CYH A  86
GLY A  41
FES  A 500 (-2.1A)
None
FES  A 500 (-2.3A)
FES  A 500 (-3.6A)
1.34A 3w9tE-1e9mA:
0.0
3w9tE-1e9mA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8v MATURE CAPSID
PROTEIN BETA


(Pariacoto virus)
PF01829
(Peptidase_A6)
4 CYH A 316
CYH A  62
GLY A  74
ASP A  72
None
1.22A 3w9tE-1f8vA:
0.0
3w9tE-1f8vA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE


(Paraburkholderia
xenovorans)
PF00355
(Rieske)
4 CYH A  43
THR A  44
CYH A  63
GLY A  68
FES  A1001 (-2.2A)
None
FES  A1001 (-2.3A)
FES  A1001 (-3.9A)
1.39A 3w9tE-1fqtA:
0.0
3w9tE-1fqtA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hv6 ALGINATE LYASE

(Sphingomonas
sp.)
PF05426
(Alginate_lyase)
4 THR A 343
ASN A 316
GLY A 313
ASP A 314
None
None
MAW  A 401 (-3.4A)
MAV  A 402 ( 4.7A)
1.24A 3w9tE-1hv6A:
undetectable
3w9tE-1hv6A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ibj CYSTATHIONINE
BETA-LYASE


(Arabidopsis
thaliana)
PF01053
(Cys_Met_Meta_PP)
4 THR A 205
ASN A 203
GLY A 177
ASP A 179
None
1.09A 3w9tE-1ibjA:
undetectable
3w9tE-1ibjA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jxi PHOSPHOMETHYLPYRIMID
INE KINASE


(Salmonella
enterica)
PF08543
(Phos_pyr_kin)
4 CYH A 213
THR A 214
GLY A  19
ASP A  23
HMH  A2001 (-3.6A)
None
HMH  A2001 ( 3.8A)
None
1.20A 3w9tE-1jxiA:
undetectable
3w9tE-1jxiA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n10 POLLEN ALLERGEN PHL
P 1


(Phleum pratense)
PF01357
(Pollen_allerg_1)
PF03330
(DPBB_1)
4 THR A1061
ASN A1060
GLY A1059
ASP A1096
None
1.35A 3w9tE-1n10A:
undetectable
3w9tE-1n10A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n5x XANTHINE
DEHYDROGENASE


(Bos taurus)
PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C)
4 ASN A1249
CYH A1247
GLY A1183
ASP A1181
None
1.30A 3w9tE-1n5xA:
undetectable
3w9tE-1n5xA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ors 33H1 FAB HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 CYH B 200
THR B 199
CYH B 145
GLY B 144
None
1.22A 3w9tE-1orsB:
undetectable
3w9tE-1orsB:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qaf PROTEIN (COPPER
AMINE OXIDASE)


(Escherichia
coli)
PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3)
PF07833
(Cu_amine_oxidN1)
4 THR A 677
ASN A 540
GLY A 538
ASP A 535
None
None
None
CA  A 802 (-3.3A)
1.24A 3w9tE-1qafA:
undetectable
3w9tE-1qafA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qho ALPHA-AMYLASE

(Geobacillus
stearothermophilus)
PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C)
4 THR A 542
ASN A 544
GLY A 519
ASP A 518
None
SO4  A1203 (-3.3A)
None
None
1.28A 3w9tE-1qhoA:
undetectable
3w9tE-1qhoA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)


(Rhinovirus A)
PF00073
(Rhv)
4 THR 1 205
ASN 1 204
GLY 1 202
ASP 1 203
None
1.04A 3w9tE-1r1a1:
undetectable
3w9tE-1r1a1:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ru3 ACETYL-COA SYNTHASE

(Carboxydothermus
hydrogenoformans)
PF03598
(CdhC)
4 THR A 216
CYH A 189
GLY A 213
ASP A 190
None
1.13A 3w9tE-1ru3A:
undetectable
3w9tE-1ru3A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1svv THREONINE ALDOLASE

(Leishmania
major)
PF01212
(Beta_elim_lyase)
4 THR A 154
ASN A 153
GLY A 184
ASP A 183
None
1.37A 3w9tE-1svvA:
undetectable
3w9tE-1svvA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9h PROBABLE GTPASE ENGC

(Bacillus
subtilis)
PF03193
(RsgA_GTPase)
PF16745
(RsgA_N)
4 THR A  67
CYH A  76
GLY A  45
ASP A  46
None
1.34A 3w9tE-1t9hA:
undetectable
3w9tE-1t9hA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ub0 PHOSPHOMETHYLPYRIMID
INE KINASE


(Thermus
thermophilus)
PF08543
(Phos_pyr_kin)
4 CYH A 210
THR A 211
GLY A  17
ASP A  21
None
1.14A 3w9tE-1ub0A:
undetectable
3w9tE-1ub0A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkn PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE


(Chlorobaculum
tepidum)
PF04371
(PAD_porph)
4 CYH A 339
THR A 341
GLY A 158
ASP A 219
None
1.35A 3w9tE-1xknA:
undetectable
3w9tE-1xknA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yd9 CORE HISTONE
MACRO-H2A.1


(Rattus
norvegicus)
PF01661
(Macro)
4 CYH A  97
THR A  40
ASN A  98
GLY A  80
None
1.36A 3w9tE-1yd9A:
undetectable
3w9tE-1yd9A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yn4 EAPH1

(Staphylococcus
aureus)
PF03642
(MAP)
4 THR A 132
ASN A 109
GLY A 111
ASP A 110
None
None
None
ZN  A 238 (-2.6A)
1.21A 3w9tE-1yn4A:
undetectable
3w9tE-1yn4A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aaf ARGININE DEIMINASE

(Pseudomonas
aeruginosa)
PF02274
(Amidinotransf)
4 THR A 281
ASN A 360
GLY A 358
ASP A 357
None
CYR  A 406 ( 3.0A)
None
None
0.83A 3w9tE-2aafA:
undetectable
3w9tE-2aafA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2y METHYLENETETRAHYDROF
OLATE
DEHYDROGENASE-METHEN
YLTETRAHYDROFOLATE
CYCLOHYDROLASE


(Mycobacterium
tuberculosis)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
4 CYH A 140
THR A 141
GLY A 121
ASP A 120
None
1.18A 3w9tE-2c2yA:
undetectable
3w9tE-2c2yA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cjs UNC-13 HOMOLOG A

(Rattus
norvegicus)
PF00168
(C2)
4 THR A  22
ASN A  66
GLY A  68
ASP A  72
None
None
None
GOL  A1158 ( 4.1A)
1.19A 3w9tE-2cjsA:
undetectable
3w9tE-2cjsA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cjt UNC-13 HOMOLOG A

(Rattus
norvegicus)
PF00168
(C2)
4 THR A  22
ASN A  66
GLY A  68
ASP A  72
None
FMT  A1138 (-3.8A)
FMT  A1137 ( 3.1A)
EDO  A1134 (-2.9A)
1.18A 3w9tE-2cjtA:
undetectable
3w9tE-2cjtA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ck0 HEAVY CHAIN)
PROTEIN
(IMMUNOGLOBULIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 CYH H 199
THR H 198
CYH H 144
GLY H 143
None
1.30A 3w9tE-2ck0H:
undetectable
3w9tE-2ck0H:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eae ALPHA-FUCOSIDASE

(Bifidobacterium
bifidum)
PF14498
(Glyco_hyd_65N_2)
4 THR A 212
ASN A 211
GLY A 139
ASP A 140
None
1.34A 3w9tE-2eaeA:
undetectable
3w9tE-2eaeA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gu2 ASPA PROTEIN

(Rattus
norvegicus)
PF04952
(AstE_AspA)
4 CYH A  60
THR A  61
ASN A  22
GLY A 184
None
SO4  A 703 (-3.8A)
None
None
1.28A 3w9tE-2gu2A:
undetectable
3w9tE-2gu2A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i5b PHOSPHOMETHYLPYRIMID
INE KINASE


(Bacillus
subtilis)
PF08543
(Phos_pyr_kin)
4 CYH A 216
THR A 217
GLY A  19
ASP A  23
None
1.21A 3w9tE-2i5bA:
undetectable
3w9tE-2i5bA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inc TOLUENE, O-XYLENE
MONOOXYGENASE
OXYGENASE SUBUNIT


(Pseudomonas
stutzeri)
PF02332
(Phenol_Hydrox)
PF04945
(YHS)
4 CYH A 400
CYH A 397
GLY A 429
ASP A 433
None
1.38A 3w9tE-2incA:
undetectable
3w9tE-2incA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jxn UNCHARACTERIZED
PROTEIN YMR074C


(Saccharomyces
cerevisiae)
PF01984
(dsDNA_bind)
4 THR A  23
ASN A  24
GLY A  25
ASP A  26
None
1.22A 3w9tE-2jxnA:
undetectable
3w9tE-2jxnA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kks UNCHARACTERIZED
PROTEIN


(Desulfitobacterium
hafniense)
PF14464
(Prok-JAB)
4 ASN A  79
CYH A  25
GLY A  26
ASP A  58
None
0.99A 3w9tE-2kksA:
undetectable
3w9tE-2kksA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mta METHYLAMINE
DEHYDROGENASE (LIGHT
SUBUNIT)


(Paracoccus
denitrificans)
PF02975
(Me-amine-dh_L)
4 THR L  44
ASN L  45
GLY L  41
ASP L  37
None
1.24A 3w9tE-2mtaL:
undetectable
3w9tE-2mtaL:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8w AGR_C_1641P

(Agrobacterium
fabrum)
PF00701
(DHDPS)
4 CYH A 228
THR A 229
GLY A 224
ASP A 225
None
1.32A 3w9tE-2r8wA:
undetectable
3w9tE-2r8wA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yn3 PUTATIVE INNER
MEMBRANE PROTEIN


(Salmonella
enterica)
PF12245
(Big_3_2)
4 THR A5233
ASN A5205
GLY A5206
ASP A5203
None
1.37A 3w9tE-2yn3A:
undetectable
3w9tE-2yn3A:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zpa UNCHARACTERIZED
PROTEIN YPFI


(Escherichia
coli)
PF05127
(Helicase_RecD)
PF08351
(DUF1726)
PF13718
(GNAT_acetyltr_2)
PF17176
(tRNA_bind_3)
4 THR A 593
CYH A 597
GLY A 596
ASP A 551
None
1.18A 3w9tE-2zpaA:
undetectable
3w9tE-2zpaA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c75 METHYLAMINE
DEHYDROGENASE LIGHT
CHAIN


(Paracoccus
versutus)
PF02975
(Me-amine-dh_L)
4 THR L  44
ASN L  45
GLY L  41
ASP L  37
None
1.23A 3w9tE-3c75L:
undetectable
3w9tE-3c75L:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d46 PUTATIVE GALACTONATE
DEHYDRATASE


(Salmonella
enterica)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 THR A  87
ASN A 135
GLY A 304
ASP A 302
None
1.02A 3w9tE-3d46A:
undetectable
3w9tE-3d46A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dqy TOLUENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT


(Pseudomonas
putida)
PF00355
(Rieske)
4 CYH A  42
THR A  43
CYH A  61
GLY A  66
FES  A 107 (-2.3A)
None
FES  A 107 (-2.2A)
FES  A 107 (-3.7A)
1.38A 3w9tE-3dqyA:
undetectable
3w9tE-3dqyA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dr2 EXPORTED
GLUCONOLACTONASE


(Xanthomonas
campestris)
PF08450
(SGL)
4 THR A 147
ASN A 134
CYH A 102
GLY A  90
None
CA  A 707 (-3.0A)
None
None
1.26A 3w9tE-3dr2A:
undetectable
3w9tE-3dr2A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ed8 YELLOW FLUORESCENCE
PROTEIN


(Aequorea
victoria)
PF01353
(GFP)
4 THR A 128
ASN A  23
GLY A  24
ASP A  21
None
1.22A 3w9tE-3ed8A:
undetectable
3w9tE-3ed8A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ekg MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME


(Azotobacter
vinelandii)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 THR A  78
ASN A 125
GLY A 295
ASP A 293
None
1.09A 3w9tE-3ekgA:
undetectable
3w9tE-3ekgA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ewn THIJ/PFPI FAMILY
PROTEIN


(Pseudomonas
syringae group
genomosp. 3)
PF01965
(DJ-1_PfpI)
4 THR A 124
CYH A 154
GLY A 122
ASP A  68
GOL  A3968 (-4.6A)
GOL  A3968 (-3.6A)
None
GOL  A3968 ( 4.7A)
1.33A 3w9tE-3ewnA:
undetectable
3w9tE-3ewnA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fou QUINOL-CYTOCHROME C
REDUCTASE, RIESKE
IRON-SULFUR SUBUNIT


(Thermus
thermophilus)
PF00355
(Rieske)
4 CYH A 132
THR A 133
CYH A 151
GLY A 156
FES  A 204 (-2.3A)
None
FES  A 204 (-2.4A)
FES  A 204 (-3.9A)
1.37A 3w9tE-3fouA:
1.7
3w9tE-3fouA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gsz RNA-DIRECTED RNA
POLYMERASE


(Hepacivirus C)
PF00998
(RdRP_3)
4 CYH A 295
THR A 294
ASN A 291
GLY A 317
None
1.28A 3w9tE-3gszA:
undetectable
3w9tE-3gszA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h8t HMUY

(Porphyromonas
gingivalis)
PF14064
(HmuY)
4 THR A 116
CYH A  86
GLY A  87
ASP A 118
None
0.62A 3w9tE-3h8tA:
undetectable
3w9tE-3h8tA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE


(Pisum sativum)
PF00171
(Aldedh)
4 THR A 289
ASN A 290
CYH A 100
GLY A 101
None
1.28A 3w9tE-3iwjA:
undetectable
3w9tE-3iwjA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jcl SPIKE GLYCOPROTEIN

(Murine
coronavirus)
PF01601
(Corona_S2)
PF09408
(Spike_rec_bind)
PF16451
(Spike_NTD)
4 THR A 784
ASN A 783
GLY A 781
ASP A 782
None
1.14A 3w9tE-3jclA:
undetectable
3w9tE-3jclA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l07 BIFUNCTIONAL PROTEIN
FOLD


(Francisella
tularensis)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
4 CYH A 140
THR A 141
GLY A 120
ASP A 119
None
None
None
EDO  A 507 (-3.9A)
1.25A 3w9tE-3l07A:
undetectable
3w9tE-3l07A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxf FERREDOXIN

(Novosphingobium
aromaticivorans)
PF00111
(Fer2)
4 CYH A  49
THR A  48
CYH A  86
GLY A  42
FES  A 500 (-2.3A)
None
FES  A 500 (-2.3A)
FES  A 500 (-3.6A)
1.39A 3w9tE-3lxfA:
undetectable
3w9tE-3lxfA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE


(Pseudomonas
aeruginosa)
PF01979
(Amidohydro_1)
4 THR A 294
ASN A 297
GLY A 299
ASP A 300
None
1.32A 3w9tE-3mduA:
undetectable
3w9tE-3mduA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntt CAPSID PROTEIN

(Adeno-associated
dependoparvovirus
B)
PF00740
(Parvo_coat)
4 THR A 349
CYH A 352
GLY A 351
ASP A 274
None
1.25A 3w9tE-3nttA:
undetectable
3w9tE-3nttA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N


(Cellvibrio
japonicus)
PF04616
(Glyco_hydro_43)
4 THR A 214
ASN A 185
GLY A 184
ASP A 168
AHR  A 337 (-4.7A)
AHR  A 338 ( 3.2A)
None
None
1.17A 3w9tE-3qefA:
undetectable
3w9tE-3qefA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qgh RNA-DIRECTED RNA
POLYMERASE


(Hepacivirus C)
PF00998
(RdRP_3)
4 CYH A 295
THR A 294
ASN A 291
GLY A 317
None
1.33A 3w9tE-3qghA:
undetectable
3w9tE-3qghA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s7v MAJOR CAPSID PROTEIN
VP1


(Human
polyomavirus 3)
PF00718
(Polyoma_coat)
4 THR A  62
ASN A  60
GLY A  59
ASP A  99
None
1.25A 3w9tE-3s7vA:
undetectable
3w9tE-3s7vA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E


(Bos taurus)
PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2)
4 ASN C1249
CYH C1247
GLY C1183
ASP C1181
None
1.31A 3w9tE-3sr6C:
undetectable
3w9tE-3sr6C:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsr RIBONUCLEASE
INHIBITOR


(Mus musculus)
PF13516
(LRR_6)
4 THR E 264
ASN E 236
GLY E 235
ASP E 262
None
None
None
EDO  E 458 (-3.0A)
1.38A 3w9tE-3tsrE:
undetectable
3w9tE-3tsrE:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3won DIPEPTIDYL
AMINOPEPTIDASE BII


(Pseudoxanthomonas
mexicana)
PF10459
(Peptidase_S46)
4 THR A 331
ASN A 334
GLY A 337
ASP A 336
None
1.34A 3w9tE-3wonA:
undetectable
3w9tE-3wonA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zqj UVRABC SYSTEM
PROTEIN A


(Mycobacterium
tuberculosis)
PF00005
(ABC_tran)
4 CYH A 415
THR A 418
CYH A 285
GLY A 287
ZN  A1956 (-2.4A)
None
ZN  A1956 (-2.4A)
None
1.23A 3w9tE-3zqjA:
undetectable
3w9tE-3zqjA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4az3 LYSOSOMAL PROTECTIVE
PROTEIN 20 KDA CHAIN
LYSOSOMAL PROTECTIVE
PROTEIN 32 KDA CHAIN


(Homo sapiens)
PF00450
(Peptidase_S10)
4 CYH B 375
ASN A 178
GLY A 179
ASP B 380
CD  B1454 (-1.9A)
None
None
None
1.12A 3w9tE-4az3B:
undetectable
3w9tE-4az3B:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c5n PHOSPHOMETHYLPYRIMID
INE KINASE


(Staphylococcus
aureus)
PF08543
(Phos_pyr_kin)
4 CYH A 214
THR A 215
GLY A  19
ASP A  23
PXL  A 300 ( 2.9A)
None
PXL  A 300 (-3.6A)
None
1.20A 3w9tE-4c5nA:
undetectable
3w9tE-4c5nA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cdo THIOREDOXIN-LIKE
PROTEIN 4A,
POLYGLUTAMINE-BINDIN
G PROTEIN


(Homo sapiens)
PF02966
(DIM1)
4 CYH A  79
THR A  80
CYH A  38
ASP A  35
None
1.17A 3w9tE-4cdoA:
undetectable
3w9tE-4cdoA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ew9 PECTATE LYASE

(Caldicellulosiruptor
bescii)
PF03211
(Pectate_lyase)
4 THR A   0
ASN A   1
GLY A  22
ASP A  21
None
MPD  A 207 (-4.7A)
None
None
0.81A 3w9tE-4ew9A:
undetectable
3w9tE-4ew9A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hst GLUTARYL-7-AMINOCEPH
ALOSPORANIC ACID
ACYLASE BETA CHAIN


(Pseudomonas)
PF01804
(Penicil_amidase)
4 THR B  69
ASN B   3
GLY B  20
ASP B  21
None
1.35A 3w9tE-4hstB:
undetectable
3w9tE-4hstB:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4inf METAL-DEPENDENT
HYDROLASE


(Novosphingobium
aromaticivorans)
PF04909
(Amidohydro_2)
4 THR A 287
ASN A 288
GLY A 290
ASP A 314
None
None
None
CA  A 401 (-2.6A)
1.05A 3w9tE-4infA:
undetectable
3w9tE-4infA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jjp PHOSPHOMETHYLPYRIMID
INE KINASE


(Clostridioides
difficile)
PF08543
(Phos_pyr_kin)
4 CYH A 213
THR A 214
GLY A  21
ASP A  25
None
1.24A 3w9tE-4jjpA:
undetectable
3w9tE-4jjpA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ltu FERREDOXIN

(Rhodopseudomonas
palustris)
PF00111
(Fer2)
4 CYH A  48
THR A  47
CYH A  86
GLY A  41
FES  A 201 (-2.2A)
None
FES  A 201 (-2.1A)
FES  A 201 (-4.0A)
1.39A 3w9tE-4ltuA:
undetectable
3w9tE-4ltuA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m00 SERINE-RICH ADHESIN
FOR PLATELETS


(Staphylococcus
aureus)
PF05345
(He_PIG)
4 THR A 479
ASN A 480
GLY A 331
ASP A 330
None
None
None
SUC  A 804 (-3.3A)
1.17A 3w9tE-4m00A:
undetectable
3w9tE-4m00A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m01 SERINE-RICH ADHESIN
FOR PLATELETS


(Staphylococcus
aureus)
no annotation 4 THR A 479
ASN A 480
GLY A 331
ASP A 330
None
None
None
GOL  A 602 (-3.3A)
1.16A 3w9tE-4m01A:
undetectable
3w9tE-4m01A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m0d N-ACETYLMURAMIC ACID
6-PHOSPHATE ETHERASE


(Haemophilus
influenzae)
PF01380
(SIS)
4 THR A 123
ASN A 122
GLY A 118
ASP A 121
None
1.29A 3w9tE-4m0dA:
undetectable
3w9tE-4m0dA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzl UNCHARACTERIZED
PROTEIN


(Staphylococcus
aureus)
PF03642
(MAP)
4 THR B 132
ASN B 109
GLY B 111
ASP B 110
None
1.23A 3w9tE-4nzlB:
undetectable
3w9tE-4nzlB:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4per RIBONUCLEASE
INHIBITOR


(Gallus gallus)
PF13516
(LRR_6)
4 THR A 378
ASN A 350
GLY A 349
ASP A 376
None
1.34A 3w9tE-4perA:
undetectable
3w9tE-4perA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkc AROMATIC AMINO ACID
AMINOTRANSFERASE


(Psychrobacter
sp. B6)
PF00155
(Aminotran_1_2)
4 CYH A 181
ASN A 345
GLY A 218
ASP A 224
None
NO3  A 407 (-3.1A)
None
None
1.38A 3w9tE-4rkcA:
undetectable
3w9tE-4rkcA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ruw ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE


(Beutenbergia
cavernae)
PF03372
(Exo_endo_phos)
4 THR A 238
ASN A 365
GLY A 346
ASP A 345
None
1.31A 3w9tE-4ruwA:
undetectable
3w9tE-4ruwA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tnu ASPARTOACYLASE

(Homo sapiens)
PF04952
(AstE_AspA)
4 CYH A  61
THR A  62
ASN A  23
GLY A 185
None
1.26A 3w9tE-4tnuA:
undetectable
3w9tE-4tnuA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqt D-HYDANTOINASE

(Brucella suis)
PF01979
(Amidohydro_1)
4 THR A 334
ASN A 332
GLY A 331
ASP A 204
None
1.29A 3w9tE-4tqtA:
undetectable
3w9tE-4tqtA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4txd CSC2

(Thermofilum
pendens)
no annotation 4 THR A 131
CYH A 155
GLY A 150
ASP A 149
None
ZN  A 401 (-2.3A)
ZN  A 401 ( 4.9A)
ZN  A 401 (-2.5A)
1.34A 3w9tE-4txdA:
undetectable
3w9tE-4txdA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7t DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A


(Homo sapiens)
PF00145
(DNA_methylase)
4 CYH A 554
ASN A 551
CYH A 549
GLY A 550
ZN  A1003 (-2.2A)
None
ZN  A1003 (-2.5A)
None
1.38A 3w9tE-4u7tA:
undetectable
3w9tE-4u7tA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uwa RYANODINE RECEPTOR 1

(Oryctolagus
cuniculus)
PF00622
(SPRY)
PF01365
(RYDR_ITPR)
PF02026
(RyR)
PF02815
(MIR)
PF08709
(Ins145_P3_rec)
4 CYH A 253
THR A 254
GLY A 250
ASP A 228
None
1.33A 3w9tE-4uwaA:
undetectable
3w9tE-4uwaA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E


(Rattus
norvegicus)
PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C)
4 ASN A1249
CYH A1247
GLY A1183
ASP A1181
None
1.32A 3w9tE-4yswA:
undetectable
3w9tE-4yswA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zf4 GREEN FLUORESCENT
PROTEIN


(Aequorea
victoria)
PF01353
(GFP)
4 THR A  78
ASN A 216
GLY A 217
ASP A 214
None
1.23A 3w9tE-4zf4A:
undetectable
3w9tE-4zf4A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqz REV PROTEIN

(Borreliella
burgdorferi)
PF03978
(Borrelia_REV)
4 THR A 133
ASN A 136
GLY A 137
ASP A 107
None
1.31A 3w9tE-5eqzA:
undetectable
3w9tE-5eqzA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewo STRUCTURAL PROTEIN

(Mamastrovirus 1)
PF12226
(Astro_capsid_p)
4 THR A 529
ASN A 531
GLY A 598
ASP A 597
None
1.20A 3w9tE-5ewoA:
undetectable
3w9tE-5ewoA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6v TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 11


(Homo sapiens)
PF00017
(SH2)
PF00102
(Y_phosphatase)
4 THR A  59
ASN A  58
GLY A  39
ASP A  40
None
1.09A 3w9tE-5i6vA:
undetectable
3w9tE-5i6vA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j5p DNA TOPOISOMERASE 4
SUBUNIT B


(Streptococcus
pneumoniae)
PF00204
(DNA_gyraseB)
PF02518
(HATPase_c)
4 THR A 115
ASN A 276
GLY A 117
ASP A  54
None
1.35A 3w9tE-5j5pA:
undetectable
3w9tE-5j5pA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwb TYPE II
NADH:UBIQUINONE
OXIDOREDUCTASE


(Plasmodium
falciparum)
PF07992
(Pyr_redox_2)
4 THR A 435
ASN A 438
GLY A 353
ASP A 354
FAD  A 601 (-3.6A)
None
FAD  A 601 ( 3.3A)
FAD  A 601 (-2.9A)
1.24A 3w9tE-5jwbA:
undetectable
3w9tE-5jwbA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnc VACUOLAR TRANSPORTER
CHAPERONE 4,CORE
HISTONE MACRO-H2A.1


(Homo sapiens;
Saccharomyces
cerevisiae)
PF01661
(Macro)
PF03105
(SPX)
4 CYH A 274
THR A 217
ASN A 275
GLY A 257
None
1.36A 3w9tE-5lncA:
undetectable
3w9tE-5lncA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mse GREEN FLUORESCENT
PROTEIN


(Aequorea
victoria)
no annotation 4 THR A 128
ASN A  23
GLY A  24
ASP A  21
None
1.18A 3w9tE-5mseA:
undetectable
3w9tE-5mseA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5njf METALLOPROTEASE TLDD

(Escherichia
coli)
PF01523
(PmbA_TldD)
4 THR A 347
ASN A 349
GLY A 350
ASP A 335
None
1.16A 3w9tE-5njfA:
undetectable
3w9tE-5njfA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x94 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 11


(Homo sapiens)
PF00017
(SH2)
4 THR A  59
ASN A  58
GLY A  39
ASP A  40
None
1.07A 3w9tE-5x94A:
undetectable
3w9tE-5x94A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y89 PUTATIVE HEMIN
TRANSPORT SYSTEM,
SUBSTRATE-BINDING
PROTEIN


(Burkholderia
cenocepacia)
no annotation 4 CYH A  73
THR A  74
GLY A  46
ASP A  70
None
None
HEM  A 401 ( 4.1A)
None
1.32A 3w9tE-5y89A:
undetectable
3w9tE-5y89A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b0n ENVELOPE
GLYCOPROTEIN GP140


(Human
immunodeficiency
virus 1)
no annotation 4 CYH G 604
THR G 605
CYH G 598
GLY G 597
None
1.14A 3w9tE-6b0nG:
undetectable
3w9tE-6b0nG:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3o SPIKE GLYCOPROTEIN

(Murine
coronavirus)
PF01601
(Corona_S2)
4 THR A 784
ASN A 783
GLY A 781
ASP A 782
None
1.39A 3w9tE-6b3oA:
undetectable
3w9tE-6b3oA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b7t GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN


(Aequorea
victoria)
no annotation 4 THR A 158
ASN A  53
GLY A  54
ASP A  51
None
1.20A 3w9tE-6b7tA:
undetectable
3w9tE-6b7tA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6de8 BIFUNCTIONAL PROTEIN
FOLD


(Campylobacter
jejuni)
no annotation 4 CYH A 139
THR A 140
GLY A 119
ASP A 118
None
1.24A 3w9tE-6de8A:
undetectable
3w9tE-6de8A:
9.95