SIMILAR PATTERNS OF AMINO ACIDS FOR 3W9T_D_W9TD506
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aor | ALDEHYDE FERREDOXINOXIDOREDUCTASE (Pyrococcusfuriosus) |
PF01314(AFOR_C)PF02730(AFOR_N) | 4 | ASP A 179GLU A 101GLY A 99TYR A 97 | None | 1.47A | 3w9tD-1aorA:0.0 | 3w9tD-1aorA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bpl | ALPHA-1,4-GLUCAN-4-GLUCANOHYDROLASE (Bacilluslicheniformis) |
PF00128(Alpha-amylase)PF09154(DUF1939) | 4 | GLU B 271GLY B 268TYR B 262GLN B 264 | None | 1.33A | 3w9tD-1bplB:undetectable | 3w9tD-1bplB:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d5t | GUANINE NUCLEOTIDEDISSOCIATIONINHIBITOR (Bos taurus) |
PF00996(GDI) | 4 | ASP A 283GLU A 42GLY A 41TYR A 286 | None | 1.18A | 3w9tD-1d5tA:0.0 | 3w9tD-1d5tA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e43 | ALPHA-AMYLASE (Bacillusamyloliquefaciens) |
PF00128(Alpha-amylase)PF09154(DUF1939) | 4 | GLU A 271GLY A 268TYR A 262GLN A 264 | None | 1.46A | 3w9tD-1e43A:0.0 | 3w9tD-1e43A:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hc7 | PROLYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon)PF09180(ProRS-C_1) | 4 | ASP A 275GLU A 340GLY A 278GLN A 10 | None | 1.24A | 3w9tD-1hc7A:0.0 | 3w9tD-1hc7A:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i35 | PROTEIN KINASE BYR2 (Schizosaccharomycespombe) |
PF14847(Ras_bdg_2) | 4 | ASP A 20GLU A 57TYR A 21GLN A 22 | None | 1.17A | 3w9tD-1i35A:undetectable | 3w9tD-1i35A:12.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i84 | SMOOTH MUSCLE MYOSINHEAVY CHAIN (Gallus gallus) |
PF00063(Myosin_head)PF00612(IQ)PF01576(Myosin_tail_1)PF02736(Myosin_N) | 4 | GLU S 178GLY S 177TYR S 586GLN S 490 | None | 1.26A | 3w9tD-1i84S:0.0 | 3w9tD-1i84S:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i9s | MRNA CAPPING ENZYME (Mus musculus) |
PF00782(DSPc) | 4 | ASP A 168GLU A 96GLY A 95TYR A 169 | None | 0.99A | 3w9tD-1i9sA:0.0 | 3w9tD-1i9sA:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jdz | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE (Sulfolobussolfataricus) |
PF01048(PNP_UDP_1) | 4 | GLU A 55GLY A 54TYR A 52GLN A 34 | None | 1.27A | 3w9tD-1jdzA:0.0 | 3w9tD-1jdzA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ks5 | ENDOGLUCANASE A (Aspergillusniger) |
PF01670(Glyco_hydro_12) | 4 | GLU A 116GLY A 113TYR A 115GLN A 194 | None | 1.40A | 3w9tD-1ks5A:undetectable | 3w9tD-1ks5A:21.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1vcl | HEMOLYTIC LECTINCEL-III (Cucumariaechinata) |
PF00652(Ricin_B_lectin) | 5 | ASP A 121GLU A 123GLY A 124TYR A 134GLN A 137 | CA A1002 (-2.8A)None CA A1002 (-4.3A)None CA A1002 ( 4.5A) | 0.62A | 3w9tD-1vclA:32.6 | 3w9tD-1vclA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vjs | ALPHA-AMYLASE (Bacilluslicheniformis) |
PF00128(Alpha-amylase)PF09154(DUF1939) | 4 | GLU A 271GLY A 268TYR A 262GLN A 264 | None | 1.25A | 3w9tD-1vjsA:undetectable | 3w9tD-1vjsA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aw2 | B AND T LYMPHOCYTEATTENUATORTUMOR NECROSISFACTOR RECEPTORSUPERFAMILY MEMBER14 (Homo sapiens) |
PF00020(TNFR_c6)PF13927(Ig_3) | 4 | GLU B 31GLY B 30TYR A 39GLN A 37 | None | 1.30A | 3w9tD-2aw2B:undetectable | 3w9tD-2aw2B:13.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3o | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Desulfovibrioafricanus) |
PF01558(POR)PF01855(POR_N)PF02775(TPP_enzyme_C)PF10371(EKR)PF13484(Fer4_16)PF17147(PFOR_II) | 4 | GLU A 230GLY A 228TYR A 225GLN A 220 | None | 0.97A | 3w9tD-2c3oA:undetectable | 3w9tD-2c3oA:16.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cuw | PURS (Thermusthermophilus) |
PF02700(PurS) | 4 | ASP A 18GLU A 11GLY A 41GLN A 20 | None | 1.36A | 3w9tD-2cuwA:undetectable | 3w9tD-2cuwA:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d7n | FILAMIN-C (Homo sapiens) |
PF00630(Filamin) | 4 | ASP A 42GLU A 23GLY A 22GLN A 20 | None | 1.45A | 3w9tD-2d7nA:undetectable | 3w9tD-2d7nA:12.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jb1 | L-AMINO ACID OXIDASE (Rhodococcusopacus) |
PF01593(Amino_oxidase) | 4 | ASP A 358GLY A 237TYR A 357GLN A 103 | None | 1.21A | 3w9tD-2jb1A:undetectable | 3w9tD-2jb1A:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jf4 | PERIPLASMICTREHALASE (Escherichiacoli) |
PF01204(Trehalase) | 4 | ASP A 160GLU A 496TYR A 157GLN A 207 | VDM A1548 (-3.0A)NoneVDM A1548 (-3.7A)VDM A1548 (-3.3A) | 1.10A | 3w9tD-2jf4A:undetectable | 3w9tD-2jf4A:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nrk | HYPOTHETICAL PROTEINGRPB (Enterococcusfaecalis) |
PF04229(GrpB) | 4 | ASP A 64GLU A 80GLY A 79GLN A 67 | None | 1.28A | 3w9tD-2nrkA:undetectable | 3w9tD-2nrkA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oby | PUTATIVE QUINONEOXIDOREDUCTASE (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | ASP A 43GLU A 64GLY A 62GLN A 46 | None | 1.18A | 3w9tD-2obyA:undetectable | 3w9tD-2obyA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oqc | PENICILLIN V ACYLASE (Bacillussubtilis) |
PF02275(CBAH) | 4 | GLU A 28GLY A 26TYR A 278GLN A 277 | None | 1.16A | 3w9tD-2oqcA:undetectable | 3w9tD-2oqcA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pbl | PUTATIVEESTERASE/LIPASE/THIOESTERASE (Ruegeria sp.TM1040) |
PF07859(Abhydrolase_3) | 4 | GLU A 46GLY A 47TYR A 44GLN A 114 | None | 1.46A | 3w9tD-2pblA:undetectable | 3w9tD-2pblA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qx2 | SEX PHEROMONESTAPH-CAM373 (Staphylococcusaureus) |
PF07537(CamS) | 4 | GLU A 83GLY A 79TYR A 248GLN A 250 | EDO A 1 ( 4.0A)EDO A 1 (-4.2A)NoneNone | 1.20A | 3w9tD-2qx2A:undetectable | 3w9tD-2qx2A:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r55 | STAR-RELATED LIPIDTRANSFER PROTEIN 5 (Homo sapiens) |
PF01852(START) | 4 | GLU A 32GLY A 35TYR A 201GLN A 205 | None | 1.09A | 3w9tD-2r55A:undetectable | 3w9tD-2r55A:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z1a | 5'-NUCLEOTIDASE (Thermusthermophilus) |
PF00149(Metallophos)PF02872(5_nucleotid_C) | 4 | GLU A 220GLY A 217TYR A 218GLN A 273 | None | 1.35A | 3w9tD-2z1aA:undetectable | 3w9tD-2z1aA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a18 | ALDOXIME DEHYDRATASE (Rhodococcuserythropolis) |
PF13816(Dehydratase_hem) | 4 | ASP A 86GLY A 340TYR A 90GLN A 49 | None | 1.05A | 3w9tD-3a18A:undetectable | 3w9tD-3a18A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e60 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN ]SYNTHASE II (Bartonellahenselae) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | ASP A 273GLU A 285GLY A 284TYR A 275 | None | 1.30A | 3w9tD-3e60A:undetectable | 3w9tD-3e60A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fbq | CONSERVED DOMAINPROTEIN (Bacillusanthracis) |
PF13786(DUF4179) | 4 | ASP A 14GLU A 22GLY A 19TYR A 21 | None | 1.39A | 3w9tD-3fbqA:undetectable | 3w9tD-3fbqA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fd0 | PUTATIVECYSTATHIONINEBETA-LYASE INVOLVEDIN ALUMINUMRESISTANCE (Listeriainnocua) |
PF06838(Met_gamma_lyase) | 4 | ASP A 314GLY A 169TYR A 203GLN A 388 | NoneEDO A 411 (-3.8A)LLP A 226 ( 3.5A)EDO A 411 (-3.5A) | 1.06A | 3w9tD-3fd0A:undetectable | 3w9tD-3fd0A:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h4h | COPPER-CONTAININGNITRITE REDUCTASE (Alcaligenesfaecalis) |
PF00394(Cu-oxidase)PF07732(Cu-oxidase_3) | 4 | GLU A 239GLY A 238TYR A 293GLN A 296 | None | 1.44A | 3w9tD-3h4hA:undetectable | 3w9tD-3h4hA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hbu | SECRETED PROTEASE C (Dickeyachrysanthemi) |
PF00353(HemolysinCabind)PF00413(Peptidase_M10)PF08548(Peptidase_M10_C) | 4 | GLU P 179GLY P 182TYR P 242GLN P 184 | None | 1.44A | 3w9tD-3hbuP:undetectable | 3w9tD-3hbuP:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ht4 | ALUMINUM RESISTANCEPROTEIN (Bacillus cereus) |
PF06838(Met_gamma_lyase) | 4 | ASP A 321GLY A 176TYR A 210GLN A 395 | None | 1.00A | 3w9tD-3ht4A:undetectable | 3w9tD-3ht4A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m50 | N.PLUMBAGINIFOLIAH+-TRANSLOCATINGATPASE MRNA (Nicotianaplumbaginifolia) |
no annotation | 4 | GLU P 928GLY P 934TYR P 954GLN P 952 | None | 1.40A | 3w9tD-3m50P:undetectable | 3w9tD-3m50P:5.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0t | SERINE/THREONINE-PROTEIN PHOSPHATASEPGAM5, MITOCHONDRIAL (Homo sapiens) |
PF00300(His_Phos_1) | 4 | ASP A 200GLU A 177TYR A 197GLN A 196 | NonePO4 A 1 (-3.4A)NoneNone | 1.03A | 3w9tD-3o0tA:undetectable | 3w9tD-3o0tA:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pdf | DIPEPTIDYL PEPTIDASE1 (Homo sapiens) |
PF00112(Peptidase_C1)PF08773(CathepsinC_exc) | 4 | ASP A 304GLU A 275GLY A 273GLN A 262 | None | 1.42A | 3w9tD-3pdfA:undetectable | 3w9tD-3pdfA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t2c | FRUCTOSE-1,6-BISPHOSPHATEALDOLASE/PHOSPHATASE (Pyrobaculumneutrophilum) |
PF01950(FBPase_3) | 4 | ASP A 44GLU A 315TYR A 313GLN A 37 | None | 1.49A | 3w9tD-3t2cA:undetectable | 3w9tD-3t2cA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tc2 | KUNITZ-TYPEPROTEINASE INHIBITORP1H5 (Solanumtuberosum) |
PF00197(Kunitz_legume) | 4 | ASP A 10GLU A 15TYR A 22GLN A 185 | None | 1.35A | 3w9tD-3tc2A:5.4 | 3w9tD-3tc2A:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tef | IRON(III) ABCTRANSPORTER,PERIPLASMICIRON-COMPOUND-BINDING PROTEIN (Vibrio cholerae) |
PF01497(Peripla_BP_2) | 4 | ASP A 233GLU A 164GLY A 161TYR A 162 | None | 1.16A | 3w9tD-3tefA:undetectable | 3w9tD-3tefA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3trb | VIRULENCE-ASSOCIATEDPROTEIN I (Coxiellaburnetii) |
PF01381(HTH_3) | 4 | GLU A 13GLY A 12TYR A 77GLN A 74 | None | 1.19A | 3w9tD-3trbA:undetectable | 3w9tD-3trbA:12.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ua4 | PROTEIN ARGININEN-METHYLTRANSFERASE5 (Caenorhabditiselegans) |
PF05185(PRMT5)PF17285(PRMT5_TIM)PF17286(PRMT5_C) | 4 | GLU A 728GLY A 564TYR A 580GLN A 578 | None | 1.46A | 3w9tD-3ua4A:undetectable | 3w9tD-3ua4A:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wn6 | ALPHA-AMYLASE (Oryza sativa) |
PF00128(Alpha-amylase)PF07821(Alpha-amyl_C2) | 4 | GLU A 39GLY A 42TYR A 44GLN A 94 | None | 1.00A | 3w9tD-3wn6A:undetectable | 3w9tD-3wn6A:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a1s | PARTNER OFINSCUTEABLE (Drosophilamelanogaster) |
PF13176(TPR_7)PF13424(TPR_12) | 4 | GLU A 337GLY A 336TYR A 302GLN A 299 | None | 1.47A | 3w9tD-4a1sA:undetectable | 3w9tD-4a1sA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ad8 | DNA REPAIR PROTEINRECN (Deinococcusradiodurans) |
PF02463(SMC_N) | 4 | GLU A 339GLY A 341TYR A 330GLN A 209 | None | 1.49A | 3w9tD-4ad8A:undetectable | 3w9tD-4ad8A:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4amc | GLUCANSUCRASE (Lactobacillusreuteri) |
PF01473(CW_binding_1)PF02324(Glyco_hydro_70) | 4 | ASP A1477GLU A1482GLY A1479TYR A1556 | None | 1.19A | 3w9tD-4amcA:undetectable | 3w9tD-4amcA:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ays | AMYLOSUCRASE (Deinococcusradiodurans) |
PF00128(Alpha-amylase) | 4 | GLU A 112GLY A 113TYR A 110GLN A 528 | None | 1.37A | 3w9tD-4aysA:undetectable | 3w9tD-4aysA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fuw | PROTEIN SLM4 (Saccharomycescerevisiae) |
PF16818(SLM4) | 4 | ASP A 117GLU A 155GLY A 153TYR A 150 | None | 1.27A | 3w9tD-4fuwA:undetectable | 3w9tD-4fuwA:15.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qfu | GLYCOSIDE HYDROLASEFAMILY 5 (Bacteroidesvulgatus) |
PF12904(Collagen_bind_2)PF13204(DUF4038) | 4 | ASP A 280GLU A 282GLY A 239TYR A 308 | NoneMRD A 501 (-2.7A)NoneNone | 1.42A | 3w9tD-4qfuA:undetectable | 3w9tD-4qfuA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xox | 3-OXOACYL-ACPSYNTHASE (Vibrio cholerae) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | ASP A 263GLU A 273GLY A 272TYR A 265 | None | 1.23A | 3w9tD-4xoxA:undetectable | 3w9tD-4xoxA:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yte | H(2)-FORMINGMETHYLENETETRAHYDROMETHANOPTERINDEHYDROGENASE-RELATED PROTEIN MJ0715 (Methanocaldococcusjannaschii) |
no annotation | 4 | GLU A 38GLY A 34TYR A 30GLN A 11 | None | 1.38A | 3w9tD-4yteA:undetectable | 3w9tD-4yteA:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zn2 | PSLG (Pseudomonasaeruginosa) |
PF00150(Cellulase) | 4 | GLU A 295GLY A 293TYR A 300GLN A 289 | None | 1.00A | 3w9tD-4zn2A:undetectable | 3w9tD-4zn2A:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c2v | HYDRAZINE SYNTHASEALPHA SUBUNIT (CandidatusKueneniastuttgartiensis) |
no annotation | 4 | GLU A 381GLY A 361TYR A 364GLN A 339 | None | 0.89A | 3w9tD-5c2vA:undetectable | 3w9tD-5c2vA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cgl | ADENOSINEMONOPHOSPHATE-PROTEIN TRANSFERASE NMFIC (Neisseriameningitidis) |
PF02661(Fic) | 4 | ASP A 15GLU A 186GLY A 187TYR A 188 | NonePEG A 201 (-3.9A)NoneNone | 1.50A | 3w9tD-5cglA:undetectable | 3w9tD-5cglA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 4 | GLU A 494GLY A 495TYR A 496GLN A 416 | None | 1.41A | 3w9tD-5dqfA:undetectable | 3w9tD-5dqfA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dtr | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-79SPECIFIC (Homo sapiens) |
PF08123(DOT1) | 4 | ASP A 142GLU A 138GLY A 137GLN A 172 | None | 1.40A | 3w9tD-5dtrA:undetectable | 3w9tD-5dtrA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gm3 | ENDOGLUCANASE-1 (Aspergillusaculeatus) |
PF01670(Glyco_hydro_12) | 4 | GLU A 118GLY A 115TYR A 117GLN A 192 | None | 1.44A | 3w9tD-5gm3A:undetectable | 3w9tD-5gm3A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw7 | GLUCOSIDASE YGJK (Escherichiacoli) |
PF01204(Trehalase) | 4 | GLU A 697GLY A 700TYR A 699GLN A 642 | None | 1.42A | 3w9tD-5gw7A:undetectable | 3w9tD-5gw7A:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h83 | HETEROYOHIMBINESYNTHASE HYS (Catharanthusroseus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | ASP A 54GLU A 74GLY A 72TYR A 53 | None ZN A 901 (-2.9A)NoneNone | 1.29A | 3w9tD-5h83A:undetectable | 3w9tD-5h83A:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hp6 | EXTRACELLULARARABINANASE (Geobacillusstearothermophilus) |
PF04616(Glyco_hydro_43)PF13385(Laminin_G_3)PF16369(GH43_C) | 4 | GLU A 832GLY A 833TYR A 831GLN A 839 | None | 1.48A | 3w9tD-5hp6A:undetectable | 3w9tD-5hp6A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5htp | PROBABLE SUGARKINASE (Synechococcuselongatus) |
PF02782(FGGY_C) | 4 | GLU A 236GLY A 235TYR A 357GLN A 361 | None | 1.35A | 3w9tD-5htpA:undetectable | 3w9tD-5htpA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i3o | BMP-2-INDUCIBLEPROTEIN KINASE (Homo sapiens) |
PF00069(Pkinase) | 4 | ASP A 161GLY A 192TYR A 194GLN A 157 | None | 1.20A | 3w9tD-5i3oA:undetectable | 3w9tD-5i3oA:18.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v5s | OUTER MEMBRANEPROTEIN TOLC (Escherichiacoli) |
PF02321(OEP) | 4 | ASP A 101GLU A 16TYR A 98GLN A 94 | None | 1.30A | 3w9tD-5v5sA:undetectable | 3w9tD-5v5sA:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y29 | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 4 | ASP A1886GLU A1889GLY A1888GLN A1808 | None | 1.37A | 3w9tD-5y29A:undetectable | 3w9tD-5y29A:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yy3 | - (-) |
no annotation | 4 | ASP A 171GLU A 533GLY A 532TYR A 170 | None | 1.40A | 3w9tD-5yy3A:undetectable | 3w9tD-5yy3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cv9 | SHORT TRANSIENTRECEPTOR POTENTIALCHANNEL 6 (Mus musculus) |
no annotation | 4 | ASP A 203GLU A 210GLY A 212TYR A 206 | None | 1.06A | 3w9tD-6cv9A:undetectable | 3w9tD-6cv9A:10.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f42 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC1 (Saccharomycescerevisiae) |
no annotation | 4 | GLU A1084GLY A1086TYR A 900GLN A 899 | None | 1.02A | 3w9tD-6f42A:undetectable | 3w9tD-6f42A:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fai | ESSENTIAL NUCLEARPROTEIN 1PROTEIN LTV1 (Saccharomycescerevisiae) |
no annotation | 4 | GLU j 369GLY j 367TYR j 371GLN i 276 | None | 1.50A | 3w9tD-6faij:undetectable | 3w9tD-6faij:10.19 |