SIMILAR PATTERNS OF AMINO ACIDS FOR 3W67_D_VIVD301_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a6g | MYOGLOBIN (Physetercatodon) |
PF00042(Globin) | 5 | LEU A 89SER A 92PHE A 43ILE A 28ILE A 107 | HEM A 154 (-4.9A)HEM A 154 (-2.6A)HEM A 154 ( 4.0A)NoneHEM A 154 ( 3.9A) | 1.29A | 3w67D-1a6gA:undetectable | 3w67D-1a6gA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1crk | CREATINE KINASE (Gallus gallus) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 5 | VAL A 244SER A 124ILE A 111ILE A 349VAL A 352 | None | 1.31A | 3w67D-1crkA:undetectable | 3w67D-1crkA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gpe | PROTEIN (GLUCOSEOXIDASE) (Penicilliumamagasakiense) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | LEU A 237ILE A 551ILE A 29ILE A 49LEU A 580 | None | 1.32A | 3w67D-1gpeA:undetectable | 3w67D-1gpeA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h9h | TRYPSIN (Sus scrofa) |
PF00089(Trypsin) | 5 | ILE E 242ILE E 47VAL E 121LEU E 209ILE E 212 | None | 1.14A | 3w67D-1h9hE:undetectable | 3w67D-1h9hE:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) |
PF00089(Trypsin) | 5 | ILE T 242ILE T 47VAL T 121LEU T 209ILE T 212 | None | 1.17A | 3w67D-1j17T:undetectable | 3w67D-1j17T:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n3p | LECTIN PAL (Pterocarpusangolensis) |
PF00139(Lectin_legB) | 5 | VAL A 172SER A 71PHE A 215ILE A 50LEU A 33 | None | 1.19A | 3w67D-1n3pA:undetectable | 3w67D-1n3pA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ozh | ACETOLACTATESYNTHASE, CATABOLIC (Klebsiellapneumoniae) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | SER A 240ILE A 204ILE A 236LEU A 231PHE A 256 | NoneNoneNonePGE A1403 ( 4.2A)PO4 A1404 (-4.7A) | 1.16A | 3w67D-1ozhA:undetectable | 3w67D-1ozhA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ozh | ACETOLACTATESYNTHASE, CATABOLIC (Klebsiellapneumoniae) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | VAL A 278SER A 240ILE A 236LEU A 231PHE A 256 | NoneNoneNonePGE A1403 ( 4.2A)PO4 A1404 (-4.7A) | 1.26A | 3w67D-1ozhA:undetectable | 3w67D-1ozhA:17.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1r5l | PROTEIN(ALPHA-TOCOPHEROLTRANSFER PROTEIN) (Homo sapiens) |
PF00650(CRAL_TRIO)PF03765(CRAL_TRIO_N) | 9 | VAL A 132SER A 136LEU A 137SER A 140PHE A 158VAL A 182PHE A 187ILE A 194LEU A 196 | VIV A 301 ( 4.7A)VIV A 301 (-3.5A)VIV A 301 ( 4.8A)VIV A 301 (-3.1A)VIV A 301 (-3.9A)VIV A 301 (-4.5A)VIV A 301 (-3.9A)VIV A 301 ( 4.5A)None | 0.55A | 3w67D-1r5lA:37.0 | 3w67D-1r5lA:89.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1r5l | PROTEIN(ALPHA-TOCOPHEROLTRANSFER PROTEIN) (Homo sapiens) |
PF00650(CRAL_TRIO)PF03765(CRAL_TRIO_N) | 11 | VAL A 132SER A 136SER A 140PHE A 158ILE A 171ILE A 179VAL A 182LEU A 183PHE A 187ILE A 194LEU A 196 | VIV A 301 ( 4.7A)VIV A 301 (-3.5A)VIV A 301 (-3.1A)VIV A 301 (-3.9A)NoneVIV A 301 ( 4.0A)VIV A 301 (-4.5A)NoneVIV A 301 (-3.9A)VIV A 301 ( 4.5A)None | 0.51A | 3w67D-1r5lA:37.0 | 3w67D-1r5lA:89.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rrh | SEED LIPOXYGENASE-3 (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | LEU A 328VAL A 284LEU A 288ILE A 315LEU A 310 | None | 1.07A | 3w67D-1rrhA:undetectable | 3w67D-1rrhA:14.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rrh | SEED LIPOXYGENASE-3 (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | PHE A 345VAL A 284LEU A 288ILE A 315LEU A 310 | None | 1.20A | 3w67D-1rrhA:undetectable | 3w67D-1rrhA:14.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr4 | PUTATIVE CITRATELYASE ALPHACHAIN/CITRATE-ACPTRANSFERASE (Salmonellaenterica) |
PF04223(CitF) | 5 | LEU A 285ILE A 404VAL A 362LEU A 402LEU A 460 | None | 1.12A | 3w67D-1xr4A:2.3 | 3w67D-1xr4A:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yb6 | (S)-ACETONE-CYANOHYDRIN LYASE (Heveabrasiliensis) |
PF00561(Abhydrolase_1) | 5 | LEU A 84VAL A 118LEU A 121ILE A 209LEU A 152 | NoneNoneNoneMNN A 300 (-4.4A)None | 1.03A | 3w67D-1yb6A:undetectable | 3w67D-1yb6A:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a5v | CARBONIC ANHYDRASE(CARBONATEDEHYDRATASE)(CARBONICDEHYDRATASE) (Mycobacteriumtuberculosis) |
PF00484(Pro_CA) | 5 | VAL A 91ILE A 175ILE A 182VAL A 101ILE A 163 | None | 1.27A | 3w67D-2a5vA:undetectable | 3w67D-2a5vA:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2an1 | PUTATIVE KINASE (Salmonellaenterica) |
PF01513(NAD_kinase) | 5 | ILE A 206ILE A 229VAL A 164LEU A 231ILE A 242 | ILE A 206 ( 0.7A)ILE A 229 ( 0.7A)VAL A 164 ( 0.6A)LEU A 231 ( 0.5A)ILE A 242 ( 0.7A) | 1.08A | 3w67D-2an1A:undetectable | 3w67D-2an1A:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bw3 | TRANSPOSASETRANSPOSASE (Muscadomestica;Musca domestica) |
PF05699(Dimer_Tnp_hAT)PF10683(DBD_Tnp_Hermes)PF10683(DBD_Tnp_Hermes) | 5 | VAL B 127ILE A 121ILE B 121VAL A 137LEU A 140 | None | 1.28A | 3w67D-2bw3B:undetectable | 3w67D-2bw3B:13.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cex | PROTEIN HI0146 (Haemophilusinfluenzae) |
PF03480(DctP) | 5 | VAL A 218LEU A 61ILE A 36ILE A 38LEU A 40 | None | 1.34A | 3w67D-2cexA:undetectable | 3w67D-2cexA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d6f | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT E (Methanothermobacterthermautotrophicus) |
PF02637(GatB_Yqey)PF02934(GatB_N)PF02938(GAD) | 5 | VAL C 200ILE C 245VAL C 239ILE C 226LEU C 8 | None | 1.21A | 3w67D-2d6fC:undetectable | 3w67D-2d6fC:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dc1 | L-ASPARTATEDEHYDROGENASE (Archaeoglobusfulgidus) |
PF01958(DUF108)PF03447(NAD_binding_3) | 5 | LEU A 218SER A 216ILE A 118ILE A 202VAL A 204 | NoneCIT A1585 (-2.6A)NoneNoneNone | 1.15A | 3w67D-2dc1A:undetectable | 3w67D-2dc1A:25.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dcl | HYPOTHETICAL UPF0166PROTEIN PH1503 (Pyrococcushorikoshii) |
PF02641(DUF190) | 5 | VAL A 30ILE A 16ILE A 14VAL A 76LEU A 12 | NoneNoneNoneAMP A 901 ( 4.5A)None | 0.87A | 3w67D-2dclA:undetectable | 3w67D-2dclA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ej9 | PUTATIVE BIOTINLIGASE (Methanocaldococcusjannaschii) |
PF02237(BPL_C)PF03099(BPL_LplA_LipB) | 5 | ILE A 125ILE A 96LEU A 90PHE A 92ILE A 74 | None | 0.97A | 3w67D-2ej9A:undetectable | 3w67D-2ej9A:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g4r | MOLYBDOPTERINBIOSYNTHESIS MOGPROTEIN (Mycobacteriumtuberculosis) |
PF00994(MoCF_biosynth) | 5 | LEU A 32ILE A 99ILE A 126VAL A 65LEU A 124 | None | 0.98A | 3w67D-2g4rA:undetectable | 3w67D-2g4rA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2him | L-ASPARAGINASE 1 (Escherichiacoli) |
PF00710(Asparaginase) | 5 | LEU A 132ILE A 87VAL A 8PHE A 49LEU A 108 | None | 1.20A | 3w67D-2himA:undetectable | 3w67D-2himA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hro | PHOSPHOENOLPYRUVATE-PROTEINPHOSPHOTRANSFERASE (Staphylococcuscarnosus) |
PF00391(PEP-utilizers)PF02896(PEP-utilizers_C)PF05524(PEP-utilisers_N) | 5 | LEU A 483SER A 550PHE A 524ILE A 538LEU A 272 | None | 1.19A | 3w67D-2hroA:2.2 | 3w67D-2hroA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2id5 | LEUCINE RICH REPEATNEURONAL 6A (Homo sapiens) |
PF07679(I-set)PF13306(LRR_5)PF13855(LRR_8) | 5 | VAL A 68PHE A 76ILE A 111ILE A 95LEU A 103 | None | 1.25A | 3w67D-2id5A:undetectable | 3w67D-2id5A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kko | POSSIBLETRANSCRIPTIONALREGULATORY PROTEIN(POSSIBLYARSR-FAMILY) (Mycobacteriumbovis) |
PF12840(HTH_20) | 5 | VAL A 15LEU A 22VAL A 93LEU A 92PHE A 90 | None | 1.25A | 3w67D-2kkoA:undetectable | 3w67D-2kkoA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mx7 | SYNERGIN GAMMA (Homo sapiens) |
no annotation | 5 | VAL A 364SER A 328ILE A 385ILE A 306LEU A 355 | None | 0.95A | 3w67D-2mx7A:undetectable | 3w67D-2mx7A:18.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nwv | XISI PROTEIN-LIKE (Trichormusvariabilis) |
PF08869(XisI) | 5 | LEU A 88ILE A 65ILE A 11VAL A 14LEU A 15 | None | 1.16A | 3w67D-2nwvA:undetectable | 3w67D-2nwvA:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2po4 | VIRION RNAPOLYMERASE (Escherichiavirus N4) |
no annotation | 5 | VAL A 693PHE A 738ILE A 777ILE A 770LEU A 739 | None | 1.02A | 3w67D-2po4A:undetectable | 3w67D-2po4A:14.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pyj | DNA POLYMERASE (Bacillus virusphi29) |
PF03175(DNA_pol_B_2) | 5 | VAL A 54PHE A 47ILE A 105ILE A 119LEU A 44 | None | 1.09A | 3w67D-2pyjA:undetectable | 3w67D-2pyjA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qen | WALKER-TYPE ATPASE (Pyrococcusabyssi) |
PF01637(ATPase_2) | 5 | LEU A 65PHE A 117ILE A 85ILE A 167LEU A 165 | None | 1.17A | 3w67D-2qenA:3.5 | 3w67D-2qenA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qor | GUANYLATE KINASE (Plasmodiumvivax) |
PF00625(Guanylate_kin) | 5 | LEU A 186ILE A 21VAL A 24LEU A 25PHE A 28 | None | 1.12A | 3w67D-2qorA:undetectable | 3w67D-2qorA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qzp | ACYLAMINO-ACID-RELEASING ENZYME (Aeropyrumpernix) |
PF00326(Peptidase_S9) | 5 | VAL A 74LEU A 37ILE A 78VAL A 67LEU A 79 | None | 1.20A | 3w67D-2qzpA:3.0 | 3w67D-2qzpA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vli | ANTIBIOTICRESISTANCE PROTEIN (Deinococcusradiodurans) |
no annotation | 5 | VAL A 34SER A 32ILE A 10ILE A 8LEU A 171 | None | 0.98A | 3w67D-2vliA:undetectable | 3w67D-2vliA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a1j | CELL CYCLECHECKPOINT PROTEINRAD1 (Homo sapiens) |
PF02144(Rad1) | 5 | SER C 231LEU C 235ILE C 179ILE C 243VAL C 241 | None | 1.10A | 3w67D-3a1jC:undetectable | 3w67D-3a1jC:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3j | PBP5 (Haemophilusinfluenzae) |
PF00768(Peptidase_S11)PF07943(PBP5_C) | 5 | LEU A 66SER A 178ILE A 191ILE A 255VAL A 257 | None | 1.08A | 3w67D-3a3jA:undetectable | 3w67D-3a3jA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bsx | PUMILIO HOMOLOG 1 (Homo sapiens) |
PF00806(PUF) | 5 | LEU A1026VAL A1049LEU A1050ILE A1065LEU A1072 | None | 1.09A | 3w67D-3bsxA:undetectable | 3w67D-3bsxA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c3j | PUTATIVETAGATOSE-6-PHOSPHATEKETOSE/ALDOSEISOMERASE (Escherichiacoli) |
PF01380(SIS) | 5 | LEU A 106ILE A 67LEU A 159PHE A 44ILE A 34 | None | 1.38A | 3w67D-3c3jA:1.4 | 3w67D-3c3jA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmv | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | ILE A 192ILE A 190VAL A 140LEU A 188LEU A 47 | None | 1.30A | 3w67D-3cmvA:undetectable | 3w67D-3cmvA:11.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cwx | PROTEIN CAGD (Helicobacterpylori) |
PF16567(CagD) | 5 | SER A 113ILE A 53VAL A 63LEU A 67ILE A 97 | None | 1.15A | 3w67D-3cwxA:undetectable | 3w67D-3cwxA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fcx | S-FORMYLGLUTATHIONEHYDROLASE (Homo sapiens) |
PF00756(Esterase) | 5 | SER A 70ILE A 265VAL A 78LEU A 48LEU A 219 | None | 1.11A | 3w67D-3fcxA:3.1 | 3w67D-3fcxA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g4g | CAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 4D (Homo sapiens) |
PF00233(PDEase_I) | 5 | VAL A 368LEU A 400VAL A 430ILE A 414LEU A 308 | None | 1.35A | 3w67D-3g4gA:undetectable | 3w67D-3g4gA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g7t | ENVELOPE PROTEIN (Dengue virus) |
PF00869(Flavi_glycoprot)PF02832(Flavi_glycop_C) | 5 | VAL A 31SER A 29ILE A 357ILE A 367LEU A 351 | None | 0.99A | 3w67D-3g7tA:undetectable | 3w67D-3g7tA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjz | TRANSALDOLASE B (Prochlorococcusmarinus) |
PF00923(TAL_FSA) | 5 | LEU A 158SER A 179ILE A 119ILE A 134LEU A 89 | None | 1.32A | 3w67D-3hjzA:undetectable | 3w67D-3hjzA:24.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6u | SERINE/THREONINE-PROTEIN KINASE CHK2 (Homo sapiens) |
PF00069(Pkinase)PF00498(FHA) | 5 | VAL A 451SER A 422LEU A 421VAL A 463LEU A 467 | None | 1.11A | 3w67D-3i6uA:undetectable | 3w67D-3i6uA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ig4 | XAA-PROAMINOPEPTIDASE (Bacillusanthracis) |
PF00557(Peptidase_M24)PF05195(AMP_N) | 5 | LEU A 229ILE A 191VAL A 194LEU A 195ILE A 408 | None | 0.68A | 3w67D-3ig4A:undetectable | 3w67D-3ig4A:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kys | TRANSCRIPTIONALENHANCER FACTORTEF-1 (Homo sapiens) |
no annotation | 5 | VAL A 293SER A 295ILE A 372VAL A 376LEU A 386 | NoneNoneBME A 700 ( 4.9A)NoneNone | 1.23A | 3w67D-3kysA:undetectable | 3w67D-3kysA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m16 | TRANSALDOLASE (Oleispiraantarctica) |
PF00923(TAL_FSA) | 5 | LEU A 162SER A 183ILE A 123ILE A 138LEU A 93 | None | 1.21A | 3w67D-3m16A:1.4 | 3w67D-3m16A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mwc | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Kosmotogaolearia) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | VAL A 109SER A 52LEU A 37ILE A 99ILE A 71 | None | 1.34A | 3w67D-3mwcA:1.0 | 3w67D-3mwcA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ntx | CYTOPLASMICL-ASPARAGINASE I (Yersinia pestis) |
PF00710(Asparaginase) | 5 | LEU A 132ILE A 87VAL A 8PHE A 49LEU A 108 | None | 1.26A | 3w67D-3ntxA:undetectable | 3w67D-3ntxA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pvc | TRNA5-METHYLAMINOMETHYL-2-THIOURIDINEBIOSYNTHESISBIFUNCTIONAL PROTEINMNMC (Yersinia pestis) |
PF01266(DAO)PF05430(Methyltransf_30) | 5 | SER A 59LEU A 92PHE A 80ILE A 98LEU A 168 | None | 1.22A | 3w67D-3pvcA:undetectable | 3w67D-3pvcA:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q6t | 43.2 KDA SALIVARYPROTEIN (Lutzomyialongipalpis) |
PF03022(MRJP) | 5 | ILE A 185VAL A 196LEU A 183ILE A 225LEU A 227 | None | 1.06A | 3w67D-3q6tA:undetectable | 3w67D-3q6tA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rks | HYDROXYNITRILASE (Manihotesculenta) |
PF00561(Abhydrolase_1) | 5 | LEU A 84VAL A 118LEU A 121ILE A 210LEU A 153 | None | 1.07A | 3w67D-3rksA:2.2 | 3w67D-3rksA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s7w | EIGHT-HEME NITRITEREDUCTASE (Thioalkalivibrionitratireducens) |
PF02335(Cytochrom_C552) | 5 | VAL A 511SER A 507SER A 503ILE A 449LEU A 103 | None | 1.18A | 3w67D-3s7wA:undetectable | 3w67D-3s7wA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqo | CYSTEINYL-TRNASYNTHETASE (Coxiellaburnetii) |
PF01406(tRNA-synt_1e)PF09190(DALR_2) | 5 | SER A 285LEU A 282ILE A 263ILE A 39LEU A 294 | None | 1.26A | 3w67D-3tqoA:undetectable | 3w67D-3tqoA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v2i | PEPTIDYL-TRNAHYDROLASE (Burkholderiathailandensis) |
PF01195(Pept_tRNA_hydro) | 5 | ILE A 2ILE A 5VAL A 27PHE A 24LEU A 196 | None | 1.28A | 3w67D-3v2iA:undetectable | 3w67D-3v2iA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vti | HYDROGENASEMATURATION FACTOR (Caldanaerobactersubterraneus) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | VAL C 245SER C 253ILE C 186ILE C 231LEU C 224 | None | 1.25A | 3w67D-3vtiC:undetectable | 3w67D-3vtiC:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zbq | PHIKZ039 (Pseudomonasvirus phiKZ) |
no annotation | 5 | ILE A 132ILE A 182VAL A 185LEU A 186ILE A 9 | GDP A 999 (-4.1A)NoneNoneNoneNone | 1.30A | 3w67D-3zbqA:undetectable | 3w67D-3zbqA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 487d | PROTEIN (50S L6RIBOSOMAL PROTEIN) (Geobacillusstearothermophilus) |
PF00347(Ribosomal_L6) | 5 | ILE J 161VAL J 106LEU J 104ILE J 114LEU J 143 | None | 1.07A | 3w67D-487dJ:undetectable | 3w67D-487dJ:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a3x | EPA1P ([Candida]glabrata) |
PF10528(GLEYA) | 5 | LEU A 207PHE A 248ILE A 219VAL A 169ILE A 109 | None | 0.90A | 3w67D-4a3xA:undetectable | 3w67D-4a3xA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a3x | EPA1P ([Candida]glabrata) |
PF10528(GLEYA) | 5 | LEU A 207PHE A 248VAL A 169LEU A 221ILE A 109 | None | 0.88A | 3w67D-4a3xA:undetectable | 3w67D-4a3xA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4asl | EPA1P ([Candida]glabrata) |
PF10528(GLEYA) | 5 | LEU A 207PHE A 248ILE A 219VAL A 169ILE A 109 | None | 0.93A | 3w67D-4aslA:undetectable | 3w67D-4aslA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4asl | EPA1P ([Candida]glabrata) |
PF10528(GLEYA) | 5 | LEU A 207PHE A 248VAL A 169LEU A 221ILE A 109 | None | 0.93A | 3w67D-4aslA:undetectable | 3w67D-4aslA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4csw | CUPIN 4 FAMILYPROTEIN (Rhodothermusmarinus) |
PF08007(Cupin_4) | 5 | LEU A 44PHE A 35ILE A 119VAL A 94LEU A 3 | None | 1.12A | 3w67D-4cswA:undetectable | 3w67D-4cswA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eaa | PEROSAMINEN-ACETYLTRANSFERASE (Caulobactervibrioides) |
PF00132(Hexapep) | 5 | VAL A 10LEU A 61ILE A 23ILE A 36VAL A 52 | None | 1.36A | 3w67D-4eaaA:undetectable | 3w67D-4eaaA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | ILE A 128ILE A 105VAL A 102ILE A 96LEU A 116 | None | 1.31A | 3w67D-4fs7A:undetectable | 3w67D-4fs7A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fzl | BACTERIOCIN (Pseudomonassyringae groupgenomosp. 3) |
PF14859(Colicin_M) | 5 | VAL A 185LEU A 207ILE A 172ILE A 162VAL A 160 | EDO A 305 (-4.9A)NoneNoneNoneNone | 1.07A | 3w67D-4fzlA:undetectable | 3w67D-4fzlA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gps | KLLA0E02245P (Kluyveromyceslactis) |
no annotation | 5 | VAL A 382PHE A 158ILE A 360ILE A 253LEU A 255 | None | 1.00A | 3w67D-4gpsA:undetectable | 3w67D-4gpsA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h2k | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Haemophilusinfluenzae) |
PF01546(Peptidase_M20) | 5 | PHE A 64ILE A 255ILE A 194LEU A 190ILE A 62 | None | 1.32A | 3w67D-4h2kA:undetectable | 3w67D-4h2kA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hao | PROBABLE INORGANICPOLYPHOSPHATE/ATP-NAD KINASE (Yersinia pestis) |
PF01513(NAD_kinase) | 5 | ILE A 206ILE A 229VAL A 164LEU A 231ILE A 242 | None | 1.10A | 3w67D-4haoA:undetectable | 3w67D-4haoA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hcy | THIAMINASE-I (Naegleriagruberi) |
no annotation | 5 | LEU A 8VAL A 281LEU A 285ILE A 32LEU A 16 | None | 1.25A | 3w67D-4hcyA:undetectable | 3w67D-4hcyA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1k | D-ALANINE--D-ALANINELIGASE (Xanthomonasoryzae) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 5 | SER A 20LEU A 21ILE A 43PHE A 57LEU A 120 | None | 1.06A | 3w67D-4l1kA:undetectable | 3w67D-4l1kA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ll8 | MYOSIN-4SWI5-DEPENDENT HOEXPRESSION PROTEIN 3 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF01843(DIL)no annotation | 5 | VAL E 135LEU E 140SER E 143PHE A1379ILE A1391 | None | 0.91A | 3w67D-4ll8E:undetectable | 3w67D-4ll8E:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mow | GLUCOSE1-DEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 5 | SER A 230LEU A 4ILE A 182ILE A 137VAL A 87 | None | 1.10A | 3w67D-4mowA:2.3 | 3w67D-4mowA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4npa | PUTATIVEUNCHARACTERIZEDPROTEIN (Vibrio cholerae) |
PF03641(Lysine_decarbox)PF11892(DUF3412)PF14793(DUF4478) | 5 | VAL A 248ILE A 286LEU A 288ILE A 305LEU A 309 | None | 1.31A | 3w67D-4npaA:undetectable | 3w67D-4npaA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rg1 | C9ORF114 (Homo sapiens) |
PF02598(Methyltrn_RNA_3) | 5 | LEU A 361ILE A 112VAL A 77ILE A 83LEU A 84 | None | 1.17A | 3w67D-4rg1A:undetectable | 3w67D-4rg1A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w5z | CHITINASE 60 (Moritellamarina) |
PF00704(Glyco_hydro_18) | 5 | ILE A 81VAL A 173LEU A 170ILE A 150LEU A 152 | None | 1.00A | 3w67D-4w5zA:2.1 | 3w67D-4w5zA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yqz | PUTATIVEOXIDOREDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 5 | SER A 215LEU A 3ILE A 168ILE A 123VAL A 71 | None | 1.11A | 3w67D-4yqzA:2.4 | 3w67D-4yqzA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b2o | CRISPR-ASSOCIATEDENDONUCLEASE CAS9 (Francisellatularensis) |
no annotation | 5 | VAL A 350LEU A 438PHE A 336ILE A 319ILE A 357 | None | 1.12A | 3w67D-5b2oA:undetectable | 3w67D-5b2oA:10.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dem | ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 5 | VAL A 28SER A 26ILE A 52ILE A 58PHE A 61 | None | 1.18A | 3w67D-5demA:undetectable | 3w67D-5demA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eyy | CENTROLOBIUMTOMENTOSUM LECTIN (Centrolobiumtomentosum) |
PF00139(Lectin_legB) | 5 | VAL A 173SER A 72PHE A 216ILE A 51LEU A 34 | None | 1.12A | 3w67D-5eyyA:undetectable | 3w67D-5eyyA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ixq | RECEPTOR-LIKEPROTEIN KINASE 5 (Arabidopsisthaliana) |
PF08263(LRRNT_2)PF13855(LRR_8) | 5 | LEU A 121PHE A 162ILE A 155ILE A 130PHE A 81 | None | 1.11A | 3w67D-5ixqA:undetectable | 3w67D-5ixqA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j62 | PUTATIVE REDUCTASE (Clostridioidesdifficile) |
PF00881(Nitroreductase) | 5 | VAL A 56LEU A 179ILE A 118ILE A 98VAL A 187 | None | 0.88A | 3w67D-5j62A:undetectable | 3w67D-5j62A:21.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mue | ALPHA-TOCOPHEROLTRANSFER PROTEIN (Homo sapiens) |
PF00650(CRAL_TRIO)PF03765(CRAL_TRIO_N) | 10 | VAL A 132SER A 136LEU A 137SER A 140PHE A 158ILE A 171VAL A 182PHE A 187ILE A 194LEU A 196 | VIV A 302 (-4.4A)VIV A 302 (-3.5A)VIV A 302 ( 4.8A)VIV A 302 (-3.2A)VIV A 302 (-3.9A)VIV A 302 ( 4.8A)VIV A 302 (-4.4A)VIV A 302 (-4.0A)VIV A 302 ( 4.6A)None | 0.45A | 3w67D-5mueA:33.4 | 3w67D-5mueA:92.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mue | ALPHA-TOCOPHEROLTRANSFER PROTEIN (Homo sapiens) |
PF00650(CRAL_TRIO)PF03765(CRAL_TRIO_N) | 11 | VAL A 132SER A 136SER A 140PHE A 158ILE A 171ILE A 179VAL A 182LEU A 183PHE A 187ILE A 194LEU A 196 | VIV A 302 (-4.4A)VIV A 302 (-3.5A)VIV A 302 (-3.2A)VIV A 302 (-3.9A)VIV A 302 ( 4.8A)VIV A 302 (-4.0A)VIV A 302 (-4.4A)NoneVIV A 302 (-4.0A)VIV A 302 ( 4.6A)None | 0.49A | 3w67D-5mueA:33.4 | 3w67D-5mueA:92.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nck | N-ACETYLMANNOSAMINEKINASE (Fusobacteriumnucleatum) |
PF00480(ROK) | 5 | LEU A 17ILE A 13ILE A 48ILE A 102LEU A 90 | None | 1.25A | 3w67D-5nckA:undetectable | 3w67D-5nckA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nxk | SERINE-RICH SECRETEDCELL WALL ANCHORED(LPXTG-MOTIF )PROTEIN (Lactobacillusreuteri) |
no annotation | 5 | LEU A 536VAL A 502LEU A 472ILE A 430LEU A 424 | None | 1.36A | 3w67D-5nxkA:undetectable | 3w67D-5nxkA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o9e | PUTATIVE U3 SMALLNUCLEOLARRIBONUCLEOPROTEIN (Chaetomiumthermophilum) |
PF04427(Brix) | 5 | LEU A 167PHE A 230ILE A 207ILE A 154LEU A 191 | None | 1.34A | 3w67D-5o9eA:undetectable | 3w67D-5o9eA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ofb | MORC FAMILY CW-TYPEZINC FINGER PROTEIN2 (Homo sapiens) |
no annotation | 5 | LEU B 247ILE B 50VAL B 37ILE B 201LEU B 204 | None | 1.34A | 3w67D-5ofbB:undetectable | 3w67D-5ofbB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ted | LMO0488 PROTEIN (Listeriamonocytogenes) |
no annotation | 5 | VAL B 255LEU B 177ILE B 258ILE B 206LEU B 202 | NoneNoneNoneNoneSKM B 401 (-3.6A) | 1.00A | 3w67D-5tedB:undetectable | 3w67D-5tedB:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u7w | APYRASE (Trifoliumrepens) |
PF01150(GDA1_CD39) | 5 | VAL A 368ILE A 379ILE A 157VAL A 164PHE A 209 | None | 1.31A | 3w67D-5u7wA:undetectable | 3w67D-5u7wA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7z | DNA POLYMERASE IIISUBUNIT BETA (Rickettsiaconorii) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | ILE A 217ILE A 130LEU A 184ILE A 162LEU A 221 | None | 1.29A | 3w67D-5w7zA:undetectable | 3w67D-5w7zA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xmr | SERINEHYDROXYMETHYLTRANSFERASE (Plasmodiumvivax) |
no annotation | 5 | VAL A 96SER A 244LEU A 99ILE A 73LEU A 46 | None | 1.15A | 3w67D-5xmrA:undetectable | 3w67D-5xmrA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyn | PLATINUM SENSITIVITYPROTEIN 3SUPPRESSOR OF HUSENSITIVITY INVOLVEDIN RECOMBINATIONPROTEIN 1 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
no annotationno annotation | 5 | VAL C 51LEU A 130PHE A 126ILE A 133LEU A 164 | None | 1.32A | 3w67D-5xynC:undetectable | 3w67D-5xynC:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6all | FE(3+)-CITRATE-BINDING PROTEIN YFMC (Bacillusanthracis) |
PF01497(Peripla_BP_2) | 5 | VAL A 61PHE A 141VAL A 55LEU A 117ILE A 39 | None | 1.04A | 3w67D-6allA:undetectable | 3w67D-6allA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b2w | PUTATIVEPEPTIDYL-ARGININEDEIMINASE FAMILYPROTEIN (Campylobacterjejuni) |
no annotation | 5 | VAL A 132ILE A 86LEU A 156ILE A 183LEU A 180 | None | 0.98A | 3w67D-6b2wA:1.2 | 3w67D-6b2wA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c3p | ATP-BINDING CASSETTESUB-FAMILY C MEMBER8 (Homo sapiens) |
no annotation | 5 | PHE E1392ILE E1344ILE E1501PHE E1495LEU E1417 | None | 1.26A | 3w67D-6c3pE:undetectable | 3w67D-6c3pE:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6co7 | PREDICTED PROTEIN (Nematostellavectensis) |
no annotation | 5 | VAL A 308ILE A 315ILE A 392VAL A 394ILE A 354 | None | 1.07A | 3w67D-6co7A:undetectable | 3w67D-6co7A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fai | ESSENTIAL NUCLEARPROTEIN 1 (Saccharomycescerevisiae) |
no annotation | 5 | LEU i 359VAL i 326LEU i 325PHE i 323LEU i 299 | NoneNoneNoneNone U 21269 ( 4.5A) | 1.29A | 3w67D-6faii:undetectable | 3w67D-6faii:undetectable |