SIMILAR PATTERNS OF AMINO ACIDS FOR 3W67_D_VIVD301

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a6g MYOGLOBIN

(Physeter
catodon)
PF00042
(Globin)
5 LEU A  89
SER A  92
PHE A  43
ILE A  28
ILE A 107
HEM  A 154 (-4.9A)
HEM  A 154 (-2.6A)
HEM  A 154 ( 4.0A)
None
HEM  A 154 ( 3.9A)
1.29A 3w67D-1a6gA:
undetectable
3w67D-1a6gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1crk CREATINE KINASE

(Gallus gallus)
PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN)
5 VAL A 244
SER A 124
ILE A 111
ILE A 349
VAL A 352
None
1.31A 3w67D-1crkA:
undetectable
3w67D-1crkA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gpe PROTEIN (GLUCOSE
OXIDASE)


(Penicillium
amagasakiense)
PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C)
5 LEU A 237
ILE A 551
ILE A  29
ILE A  49
LEU A 580
None
1.32A 3w67D-1gpeA:
undetectable
3w67D-1gpeA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h9h TRYPSIN

(Sus scrofa)
PF00089
(Trypsin)
5 ILE E 242
ILE E  47
VAL E 121
LEU E 209
ILE E 212
None
1.14A 3w67D-1h9hE:
undetectable
3w67D-1h9hE:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j17 TRYPSIN II, ANIONIC

(Rattus
norvegicus)
PF00089
(Trypsin)
5 ILE T 242
ILE T  47
VAL T 121
LEU T 209
ILE T 212
None
1.17A 3w67D-1j17T:
undetectable
3w67D-1j17T:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n3p LECTIN PAL

(Pterocarpus
angolensis)
PF00139
(Lectin_legB)
5 VAL A 172
SER A  71
PHE A 215
ILE A  50
LEU A  33
None
1.19A 3w67D-1n3pA:
undetectable
3w67D-1n3pA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ozh ACETOLACTATE
SYNTHASE, CATABOLIC


(Klebsiella
pneumoniae)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
5 SER A 240
ILE A 204
ILE A 236
LEU A 231
PHE A 256
None
None
None
PGE  A1403 ( 4.2A)
PO4  A1404 (-4.7A)
1.16A 3w67D-1ozhA:
undetectable
3w67D-1ozhA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ozh ACETOLACTATE
SYNTHASE, CATABOLIC


(Klebsiella
pneumoniae)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
5 VAL A 278
SER A 240
ILE A 236
LEU A 231
PHE A 256
None
None
None
PGE  A1403 ( 4.2A)
PO4  A1404 (-4.7A)
1.26A 3w67D-1ozhA:
undetectable
3w67D-1ozhA:
17.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1r5l PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)


(Homo sapiens)
PF00650
(CRAL_TRIO)
PF03765
(CRAL_TRIO_N)
9 VAL A 132
SER A 136
LEU A 137
SER A 140
PHE A 158
VAL A 182
PHE A 187
ILE A 194
LEU A 196
VIV  A 301 ( 4.7A)
VIV  A 301 (-3.5A)
VIV  A 301 ( 4.8A)
VIV  A 301 (-3.1A)
VIV  A 301 (-3.9A)
VIV  A 301 (-4.5A)
VIV  A 301 (-3.9A)
VIV  A 301 ( 4.5A)
None
0.55A 3w67D-1r5lA:
37.0
3w67D-1r5lA:
89.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1r5l PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)


(Homo sapiens)
PF00650
(CRAL_TRIO)
PF03765
(CRAL_TRIO_N)
11 VAL A 132
SER A 136
SER A 140
PHE A 158
ILE A 171
ILE A 179
VAL A 182
LEU A 183
PHE A 187
ILE A 194
LEU A 196
VIV  A 301 ( 4.7A)
VIV  A 301 (-3.5A)
VIV  A 301 (-3.1A)
VIV  A 301 (-3.9A)
None
VIV  A 301 ( 4.0A)
VIV  A 301 (-4.5A)
None
VIV  A 301 (-3.9A)
VIV  A 301 ( 4.5A)
None
0.51A 3w67D-1r5lA:
37.0
3w67D-1r5lA:
89.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rrh SEED LIPOXYGENASE-3

(Glycine max)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
5 LEU A 328
VAL A 284
LEU A 288
ILE A 315
LEU A 310
None
1.07A 3w67D-1rrhA:
undetectable
3w67D-1rrhA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rrh SEED LIPOXYGENASE-3

(Glycine max)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
5 PHE A 345
VAL A 284
LEU A 288
ILE A 315
LEU A 310
None
1.20A 3w67D-1rrhA:
undetectable
3w67D-1rrhA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xr4 PUTATIVE CITRATE
LYASE ALPHA
CHAIN/CITRATE-ACP
TRANSFERASE


(Salmonella
enterica)
PF04223
(CitF)
5 LEU A 285
ILE A 404
VAL A 362
LEU A 402
LEU A 460
None
1.12A 3w67D-1xr4A:
2.3
3w67D-1xr4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yb6 (S)-ACETONE-CYANOHYD
RIN LYASE


(Hevea
brasiliensis)
PF00561
(Abhydrolase_1)
5 LEU A  84
VAL A 118
LEU A 121
ILE A 209
LEU A 152
None
None
None
MNN  A 300 (-4.4A)
None
1.03A 3w67D-1yb6A:
undetectable
3w67D-1yb6A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)


(Mycobacterium
tuberculosis)
PF00484
(Pro_CA)
5 VAL A  91
ILE A 175
ILE A 182
VAL A 101
ILE A 163
None
1.27A 3w67D-2a5vA:
undetectable
3w67D-2a5vA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2an1 PUTATIVE KINASE

(Salmonella
enterica)
PF01513
(NAD_kinase)
5 ILE A 206
ILE A 229
VAL A 164
LEU A 231
ILE A 242
ILE  A 206 ( 0.7A)
ILE  A 229 ( 0.7A)
VAL  A 164 ( 0.6A)
LEU  A 231 ( 0.5A)
ILE  A 242 ( 0.7A)
1.08A 3w67D-2an1A:
undetectable
3w67D-2an1A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bw3 TRANSPOSASE
TRANSPOSASE


(Musca
domestica;
Musca domestica)
PF05699
(Dimer_Tnp_hAT)
PF10683
(DBD_Tnp_Hermes)
PF10683
(DBD_Tnp_Hermes)
5 VAL B 127
ILE A 121
ILE B 121
VAL A 137
LEU A 140
None
1.28A 3w67D-2bw3B:
undetectable
3w67D-2bw3B:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cex PROTEIN HI0146

(Haemophilus
influenzae)
PF03480
(DctP)
5 VAL A 218
LEU A  61
ILE A  36
ILE A  38
LEU A  40
None
1.34A 3w67D-2cexA:
undetectable
3w67D-2cexA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d6f GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT E


(Methanothermobacter
thermautotrophicus)
PF02637
(GatB_Yqey)
PF02934
(GatB_N)
PF02938
(GAD)
5 VAL C 200
ILE C 245
VAL C 239
ILE C 226
LEU C   8
None
1.21A 3w67D-2d6fC:
undetectable
3w67D-2d6fC:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dc1 L-ASPARTATE
DEHYDROGENASE


(Archaeoglobus
fulgidus)
PF01958
(DUF108)
PF03447
(NAD_binding_3)
5 LEU A 218
SER A 216
ILE A 118
ILE A 202
VAL A 204
None
CIT  A1585 (-2.6A)
None
None
None
1.15A 3w67D-2dc1A:
undetectable
3w67D-2dc1A:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dcl HYPOTHETICAL UPF0166
PROTEIN PH1503


(Pyrococcus
horikoshii)
PF02641
(DUF190)
5 VAL A  30
ILE A  16
ILE A  14
VAL A  76
LEU A  12
None
None
None
AMP  A 901 ( 4.5A)
None
0.87A 3w67D-2dclA:
undetectable
3w67D-2dclA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ej9 PUTATIVE BIOTIN
LIGASE


(Methanocaldococcus
jannaschii)
PF02237
(BPL_C)
PF03099
(BPL_LplA_LipB)
5 ILE A 125
ILE A  96
LEU A  90
PHE A  92
ILE A  74
None
0.97A 3w67D-2ej9A:
undetectable
3w67D-2ej9A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN


(Mycobacterium
tuberculosis)
PF00994
(MoCF_biosynth)
5 LEU A  32
ILE A  99
ILE A 126
VAL A  65
LEU A 124
None
0.98A 3w67D-2g4rA:
undetectable
3w67D-2g4rA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2him L-ASPARAGINASE 1

(Escherichia
coli)
PF00710
(Asparaginase)
5 LEU A 132
ILE A  87
VAL A   8
PHE A  49
LEU A 108
None
1.20A 3w67D-2himA:
undetectable
3w67D-2himA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hro PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE


(Staphylococcus
carnosus)
PF00391
(PEP-utilizers)
PF02896
(PEP-utilizers_C)
PF05524
(PEP-utilisers_N)
5 LEU A 483
SER A 550
PHE A 524
ILE A 538
LEU A 272
None
1.19A 3w67D-2hroA:
2.2
3w67D-2hroA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2id5 LEUCINE RICH REPEAT
NEURONAL 6A


(Homo sapiens)
PF07679
(I-set)
PF13306
(LRR_5)
PF13855
(LRR_8)
5 VAL A  68
PHE A  76
ILE A 111
ILE A  95
LEU A 103
None
1.25A 3w67D-2id5A:
undetectable
3w67D-2id5A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kko POSSIBLE
TRANSCRIPTIONAL
REGULATORY PROTEIN
(POSSIBLY
ARSR-FAMILY)


(Mycobacterium
bovis)
PF12840
(HTH_20)
5 VAL A  15
LEU A  22
VAL A  93
LEU A  92
PHE A  90
None
1.25A 3w67D-2kkoA:
undetectable
3w67D-2kkoA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mx7 SYNERGIN GAMMA

(Homo sapiens)
no annotation 5 VAL A 364
SER A 328
ILE A 385
ILE A 306
LEU A 355
None
0.95A 3w67D-2mx7A:
undetectable
3w67D-2mx7A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nwv XISI PROTEIN-LIKE

(Trichormus
variabilis)
PF08869
(XisI)
5 LEU A  88
ILE A  65
ILE A  11
VAL A  14
LEU A  15
None
1.16A 3w67D-2nwvA:
undetectable
3w67D-2nwvA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE


(Escherichia
virus N4)
no annotation 5 VAL A 693
PHE A 738
ILE A 777
ILE A 770
LEU A 739
None
1.02A 3w67D-2po4A:
undetectable
3w67D-2po4A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyj DNA POLYMERASE

(Bacillus virus
phi29)
PF03175
(DNA_pol_B_2)
5 VAL A  54
PHE A  47
ILE A 105
ILE A 119
LEU A  44
None
1.09A 3w67D-2pyjA:
undetectable
3w67D-2pyjA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qen WALKER-TYPE ATPASE

(Pyrococcus
abyssi)
PF01637
(ATPase_2)
5 LEU A  65
PHE A 117
ILE A  85
ILE A 167
LEU A 165
None
1.17A 3w67D-2qenA:
3.5
3w67D-2qenA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qor GUANYLATE KINASE

(Plasmodium
vivax)
PF00625
(Guanylate_kin)
5 LEU A 186
ILE A  21
VAL A  24
LEU A  25
PHE A  28
None
1.12A 3w67D-2qorA:
undetectable
3w67D-2qorA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzp ACYLAMINO-ACID-RELEA
SING ENZYME


(Aeropyrum
pernix)
PF00326
(Peptidase_S9)
5 VAL A  74
LEU A  37
ILE A  78
VAL A  67
LEU A  79
None
1.20A 3w67D-2qzpA:
3.0
3w67D-2qzpA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vli ANTIBIOTIC
RESISTANCE PROTEIN


(Deinococcus
radiodurans)
no annotation 5 VAL A  34
SER A  32
ILE A  10
ILE A   8
LEU A 171
None
0.98A 3w67D-2vliA:
undetectable
3w67D-2vliA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1j CELL CYCLE
CHECKPOINT PROTEIN
RAD1


(Homo sapiens)
PF02144
(Rad1)
5 SER C 231
LEU C 235
ILE C 179
ILE C 243
VAL C 241
None
1.10A 3w67D-3a1jC:
undetectable
3w67D-3a1jC:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a3j PBP5

(Haemophilus
influenzae)
PF00768
(Peptidase_S11)
PF07943
(PBP5_C)
5 LEU A  66
SER A 178
ILE A 191
ILE A 255
VAL A 257
None
1.08A 3w67D-3a3jA:
undetectable
3w67D-3a3jA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bsx PUMILIO HOMOLOG 1

(Homo sapiens)
PF00806
(PUF)
5 LEU A1026
VAL A1049
LEU A1050
ILE A1065
LEU A1072
None
1.09A 3w67D-3bsxA:
undetectable
3w67D-3bsxA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c3j PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE


(Escherichia
coli)
PF01380
(SIS)
5 LEU A 106
ILE A  67
LEU A 159
PHE A  44
ILE A  34
None
1.38A 3w67D-3c3jA:
1.4
3w67D-3c3jA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmv PROTEIN RECA

(Escherichia
coli)
PF00154
(RecA)
5 ILE A 192
ILE A 190
VAL A 140
LEU A 188
LEU A  47
None
1.30A 3w67D-3cmvA:
undetectable
3w67D-3cmvA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cwx PROTEIN CAGD

(Helicobacter
pylori)
PF16567
(CagD)
5 SER A 113
ILE A  53
VAL A  63
LEU A  67
ILE A  97
None
1.15A 3w67D-3cwxA:
undetectable
3w67D-3cwxA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcx S-FORMYLGLUTATHIONE
HYDROLASE


(Homo sapiens)
PF00756
(Esterase)
5 SER A  70
ILE A 265
VAL A  78
LEU A  48
LEU A 219
None
1.11A 3w67D-3fcxA:
3.1
3w67D-3fcxA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g4g CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D


(Homo sapiens)
PF00233
(PDEase_I)
5 VAL A 368
LEU A 400
VAL A 430
ILE A 414
LEU A 308
None
1.35A 3w67D-3g4gA:
undetectable
3w67D-3g4gA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7t ENVELOPE PROTEIN

(Dengue virus)
PF00869
(Flavi_glycoprot)
PF02832
(Flavi_glycop_C)
5 VAL A  31
SER A  29
ILE A 357
ILE A 367
LEU A 351
None
0.99A 3w67D-3g7tA:
undetectable
3w67D-3g7tA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjz TRANSALDOLASE B

(Prochlorococcus
marinus)
PF00923
(TAL_FSA)
5 LEU A 158
SER A 179
ILE A 119
ILE A 134
LEU A  89
None
1.32A 3w67D-3hjzA:
undetectable
3w67D-3hjzA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6u SERINE/THREONINE-PRO
TEIN KINASE CHK2


(Homo sapiens)
PF00069
(Pkinase)
PF00498
(FHA)
5 VAL A 451
SER A 422
LEU A 421
VAL A 463
LEU A 467
None
1.11A 3w67D-3i6uA:
undetectable
3w67D-3i6uA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ig4 XAA-PRO
AMINOPEPTIDASE


(Bacillus
anthracis)
PF00557
(Peptidase_M24)
PF05195
(AMP_N)
5 LEU A 229
ILE A 191
VAL A 194
LEU A 195
ILE A 408
None
0.68A 3w67D-3ig4A:
undetectable
3w67D-3ig4A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kys TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-1


(Homo sapiens)
no annotation 5 VAL A 293
SER A 295
ILE A 372
VAL A 376
LEU A 386
None
None
BME  A 700 ( 4.9A)
None
None
1.23A 3w67D-3kysA:
undetectable
3w67D-3kysA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m16 TRANSALDOLASE

(Oleispira
antarctica)
PF00923
(TAL_FSA)
5 LEU A 162
SER A 183
ILE A 123
ILE A 138
LEU A  93
None
1.21A 3w67D-3m16A:
1.4
3w67D-3m16A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mwc MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN


(Kosmotoga
olearia)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
5 VAL A 109
SER A  52
LEU A  37
ILE A  99
ILE A  71
None
1.34A 3w67D-3mwcA:
1.0
3w67D-3mwcA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntx CYTOPLASMIC
L-ASPARAGINASE I


(Yersinia pestis)
PF00710
(Asparaginase)
5 LEU A 132
ILE A  87
VAL A   8
PHE A  49
LEU A 108
None
1.26A 3w67D-3ntxA:
undetectable
3w67D-3ntxA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvc TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC


(Yersinia pestis)
PF01266
(DAO)
PF05430
(Methyltransf_30)
5 SER A  59
LEU A  92
PHE A  80
ILE A  98
LEU A 168
None
1.22A 3w67D-3pvcA:
undetectable
3w67D-3pvcA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6t 43.2 KDA SALIVARY
PROTEIN


(Lutzomyia
longipalpis)
PF03022
(MRJP)
5 ILE A 185
VAL A 196
LEU A 183
ILE A 225
LEU A 227
None
1.06A 3w67D-3q6tA:
undetectable
3w67D-3q6tA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rks HYDROXYNITRILASE

(Manihot
esculenta)
PF00561
(Abhydrolase_1)
5 LEU A  84
VAL A 118
LEU A 121
ILE A 210
LEU A 153
None
1.07A 3w67D-3rksA:
2.2
3w67D-3rksA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s7w EIGHT-HEME NITRITE
REDUCTASE


(Thioalkalivibrio
nitratireducens)
PF02335
(Cytochrom_C552)
5 VAL A 511
SER A 507
SER A 503
ILE A 449
LEU A 103
None
1.18A 3w67D-3s7wA:
undetectable
3w67D-3s7wA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqo CYSTEINYL-TRNA
SYNTHETASE


(Coxiella
burnetii)
PF01406
(tRNA-synt_1e)
PF09190
(DALR_2)
5 SER A 285
LEU A 282
ILE A 263
ILE A  39
LEU A 294
None
1.26A 3w67D-3tqoA:
undetectable
3w67D-3tqoA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v2i PEPTIDYL-TRNA
HYDROLASE


(Burkholderia
thailandensis)
PF01195
(Pept_tRNA_hydro)
5 ILE A   2
ILE A   5
VAL A  27
PHE A  24
LEU A 196
None
1.28A 3w67D-3v2iA:
undetectable
3w67D-3v2iA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vti HYDROGENASE
MATURATION FACTOR


(Caldanaerobacter
subterraneus)
PF00586
(AIRS)
PF02769
(AIRS_C)
5 VAL C 245
SER C 253
ILE C 186
ILE C 231
LEU C 224
None
1.25A 3w67D-3vtiC:
undetectable
3w67D-3vtiC:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zbq PHIKZ039

(Pseudomonas
virus phiKZ)
no annotation 5 ILE A 132
ILE A 182
VAL A 185
LEU A 186
ILE A   9
GDP  A 999 (-4.1A)
None
None
None
None
1.30A 3w67D-3zbqA:
undetectable
3w67D-3zbqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
487d PROTEIN (50S L6
RIBOSOMAL PROTEIN)


(Geobacillus
stearothermophilus)
PF00347
(Ribosomal_L6)
5 ILE J 161
VAL J 106
LEU J 104
ILE J 114
LEU J 143
None
1.07A 3w67D-487dJ:
undetectable
3w67D-487dJ:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3x EPA1P

([Candida]
glabrata)
PF10528
(GLEYA)
5 LEU A 207
PHE A 248
ILE A 219
VAL A 169
ILE A 109
None
0.90A 3w67D-4a3xA:
undetectable
3w67D-4a3xA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3x EPA1P

([Candida]
glabrata)
PF10528
(GLEYA)
5 LEU A 207
PHE A 248
VAL A 169
LEU A 221
ILE A 109
None
0.88A 3w67D-4a3xA:
undetectable
3w67D-4a3xA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4asl EPA1P

([Candida]
glabrata)
PF10528
(GLEYA)
5 LEU A 207
PHE A 248
ILE A 219
VAL A 169
ILE A 109
None
0.93A 3w67D-4aslA:
undetectable
3w67D-4aslA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4asl EPA1P

([Candida]
glabrata)
PF10528
(GLEYA)
5 LEU A 207
PHE A 248
VAL A 169
LEU A 221
ILE A 109
None
0.93A 3w67D-4aslA:
undetectable
3w67D-4aslA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4csw CUPIN 4 FAMILY
PROTEIN


(Rhodothermus
marinus)
PF08007
(Cupin_4)
5 LEU A  44
PHE A  35
ILE A 119
VAL A  94
LEU A   3
None
1.12A 3w67D-4cswA:
undetectable
3w67D-4cswA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eaa PEROSAMINE
N-ACETYLTRANSFERASE


(Caulobacter
vibrioides)
PF00132
(Hexapep)
5 VAL A  10
LEU A  61
ILE A  23
ILE A  36
VAL A  52
None
1.36A 3w67D-4eaaA:
undetectable
3w67D-4eaaA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fs7 UNCHARACTERIZED
PROTEIN


(Bacteroides
ovatus)
PF13306
(LRR_5)
5 ILE A 128
ILE A 105
VAL A 102
ILE A  96
LEU A 116
None
1.31A 3w67D-4fs7A:
undetectable
3w67D-4fs7A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzl BACTERIOCIN

(Pseudomonas
syringae group
genomosp. 3)
PF14859
(Colicin_M)
5 VAL A 185
LEU A 207
ILE A 172
ILE A 162
VAL A 160
EDO  A 305 (-4.9A)
None
None
None
None
1.07A 3w67D-4fzlA:
undetectable
3w67D-4fzlA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gps KLLA0E02245P

(Kluyveromyces
lactis)
no annotation 5 VAL A 382
PHE A 158
ILE A 360
ILE A 253
LEU A 255
None
1.00A 3w67D-4gpsA:
undetectable
3w67D-4gpsA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h2k SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE


(Haemophilus
influenzae)
PF01546
(Peptidase_M20)
5 PHE A  64
ILE A 255
ILE A 194
LEU A 190
ILE A  62
None
1.32A 3w67D-4h2kA:
undetectable
3w67D-4h2kA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hao PROBABLE INORGANIC
POLYPHOSPHATE/ATP-NA
D KINASE


(Yersinia pestis)
PF01513
(NAD_kinase)
5 ILE A 206
ILE A 229
VAL A 164
LEU A 231
ILE A 242
None
1.10A 3w67D-4haoA:
undetectable
3w67D-4haoA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hcy THIAMINASE-I

(Naegleria
gruberi)
no annotation 5 LEU A   8
VAL A 281
LEU A 285
ILE A  32
LEU A  16
None
1.25A 3w67D-4hcyA:
undetectable
3w67D-4hcyA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1k D-ALANINE--D-ALANINE
LIGASE


(Xanthomonas
oryzae)
PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C)
5 SER A  20
LEU A  21
ILE A  43
PHE A  57
LEU A 120
None
1.06A 3w67D-4l1kA:
undetectable
3w67D-4l1kA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ll8 MYOSIN-4
SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
PF01843
(DIL)
no annotation
5 VAL E 135
LEU E 140
SER E 143
PHE A1379
ILE A1391
None
0.91A 3w67D-4ll8E:
undetectable
3w67D-4ll8E:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mow GLUCOSE
1-DEHYDROGENASE


(Burkholderia
cenocepacia)
PF13561
(adh_short_C2)
5 SER A 230
LEU A   4
ILE A 182
ILE A 137
VAL A  87
None
1.10A 3w67D-4mowA:
2.3
3w67D-4mowA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4npa PUTATIVE
UNCHARACTERIZED
PROTEIN


(Vibrio cholerae)
PF03641
(Lysine_decarbox)
PF11892
(DUF3412)
PF14793
(DUF4478)
5 VAL A 248
ILE A 286
LEU A 288
ILE A 305
LEU A 309
None
1.31A 3w67D-4npaA:
undetectable
3w67D-4npaA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rg1 C9ORF114

(Homo sapiens)
PF02598
(Methyltrn_RNA_3)
5 LEU A 361
ILE A 112
VAL A  77
ILE A  83
LEU A  84
None
1.17A 3w67D-4rg1A:
undetectable
3w67D-4rg1A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5z CHITINASE 60

(Moritella
marina)
PF00704
(Glyco_hydro_18)
5 ILE A  81
VAL A 173
LEU A 170
ILE A 150
LEU A 152
None
1.00A 3w67D-4w5zA:
2.1
3w67D-4w5zA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yqz PUTATIVE
OXIDOREDUCTASE


(Thermus
thermophilus)
PF13561
(adh_short_C2)
5 SER A 215
LEU A   3
ILE A 168
ILE A 123
VAL A  71
None
1.11A 3w67D-4yqzA:
2.4
3w67D-4yqzA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b2o CRISPR-ASSOCIATED
ENDONUCLEASE CAS9


(Francisella
tularensis)
no annotation 5 VAL A 350
LEU A 438
PHE A 336
ILE A 319
ILE A 357
None
1.12A 3w67D-5b2oA:
undetectable
3w67D-5b2oA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dem ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE


(Pseudomonas
aeruginosa)
PF00132
(Hexapep)
PF13720
(Acetyltransf_11)
5 VAL A  28
SER A  26
ILE A  52
ILE A  58
PHE A  61
None
1.18A 3w67D-5demA:
undetectable
3w67D-5demA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eyy CENTROLOBIUM
TOMENTOSUM LECTIN


(Centrolobium
tomentosum)
PF00139
(Lectin_legB)
5 VAL A 173
SER A  72
PHE A 216
ILE A  51
LEU A  34
None
1.12A 3w67D-5eyyA:
undetectable
3w67D-5eyyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ixq RECEPTOR-LIKE
PROTEIN KINASE 5


(Arabidopsis
thaliana)
PF08263
(LRRNT_2)
PF13855
(LRR_8)
5 LEU A 121
PHE A 162
ILE A 155
ILE A 130
PHE A  81
None
1.11A 3w67D-5ixqA:
undetectable
3w67D-5ixqA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j62 PUTATIVE REDUCTASE

(Clostridioides
difficile)
PF00881
(Nitroreductase)
5 VAL A  56
LEU A 179
ILE A 118
ILE A  98
VAL A 187
None
0.88A 3w67D-5j62A:
undetectable
3w67D-5j62A:
21.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mue ALPHA-TOCOPHEROL
TRANSFER PROTEIN


(Homo sapiens)
PF00650
(CRAL_TRIO)
PF03765
(CRAL_TRIO_N)
10 VAL A 132
SER A 136
LEU A 137
SER A 140
PHE A 158
ILE A 171
VAL A 182
PHE A 187
ILE A 194
LEU A 196
VIV  A 302 (-4.4A)
VIV  A 302 (-3.5A)
VIV  A 302 ( 4.8A)
VIV  A 302 (-3.2A)
VIV  A 302 (-3.9A)
VIV  A 302 ( 4.8A)
VIV  A 302 (-4.4A)
VIV  A 302 (-4.0A)
VIV  A 302 ( 4.6A)
None
0.45A 3w67D-5mueA:
33.4
3w67D-5mueA:
92.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mue ALPHA-TOCOPHEROL
TRANSFER PROTEIN


(Homo sapiens)
PF00650
(CRAL_TRIO)
PF03765
(CRAL_TRIO_N)
11 VAL A 132
SER A 136
SER A 140
PHE A 158
ILE A 171
ILE A 179
VAL A 182
LEU A 183
PHE A 187
ILE A 194
LEU A 196
VIV  A 302 (-4.4A)
VIV  A 302 (-3.5A)
VIV  A 302 (-3.2A)
VIV  A 302 (-3.9A)
VIV  A 302 ( 4.8A)
VIV  A 302 (-4.0A)
VIV  A 302 (-4.4A)
None
VIV  A 302 (-4.0A)
VIV  A 302 ( 4.6A)
None
0.49A 3w67D-5mueA:
33.4
3w67D-5mueA:
92.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nck N-ACETYLMANNOSAMINE
KINASE


(Fusobacterium
nucleatum)
PF00480
(ROK)
5 LEU A  17
ILE A  13
ILE A  48
ILE A 102
LEU A  90
None
1.25A 3w67D-5nckA:
undetectable
3w67D-5nckA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nxk SERINE-RICH SECRETED
CELL WALL ANCHORED
(LPXTG-MOTIF )
PROTEIN


(Lactobacillus
reuteri)
no annotation 5 LEU A 536
VAL A 502
LEU A 472
ILE A 430
LEU A 424
None
1.36A 3w67D-5nxkA:
undetectable
3w67D-5nxkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN


(Chaetomium
thermophilum)
PF04427
(Brix)
5 LEU A 167
PHE A 230
ILE A 207
ILE A 154
LEU A 191
None
1.34A 3w67D-5o9eA:
undetectable
3w67D-5o9eA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2


(Homo sapiens)
no annotation 5 LEU B 247
ILE B  50
VAL B  37
ILE B 201
LEU B 204
None
1.34A 3w67D-5ofbB:
undetectable
3w67D-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ted LMO0488 PROTEIN

(Listeria
monocytogenes)
no annotation 5 VAL B 255
LEU B 177
ILE B 258
ILE B 206
LEU B 202
None
None
None
None
SKM  B 401 (-3.6A)
1.00A 3w67D-5tedB:
undetectable
3w67D-5tedB:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7w APYRASE

(Trifolium
repens)
PF01150
(GDA1_CD39)
5 VAL A 368
ILE A 379
ILE A 157
VAL A 164
PHE A 209
None
1.31A 3w67D-5u7wA:
undetectable
3w67D-5u7wA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7z DNA POLYMERASE III
SUBUNIT BETA


(Rickettsia
conorii)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
5 ILE A 217
ILE A 130
LEU A 184
ILE A 162
LEU A 221
None
1.29A 3w67D-5w7zA:
undetectable
3w67D-5w7zA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmr SERINE
HYDROXYMETHYLTRANSFE
RASE


(Plasmodium
vivax)
no annotation 5 VAL A  96
SER A 244
LEU A  99
ILE A  73
LEU A  46
None
1.15A 3w67D-5xmrA:
undetectable
3w67D-5xmrA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyn PLATINUM SENSITIVITY
PROTEIN 3
SUPPRESSOR OF HU
SENSITIVITY INVOLVED
IN RECOMBINATION
PROTEIN 1


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
no annotation
no annotation
5 VAL C  51
LEU A 130
PHE A 126
ILE A 133
LEU A 164
None
1.32A 3w67D-5xynC:
undetectable
3w67D-5xynC:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC


(Bacillus
anthracis)
PF01497
(Peripla_BP_2)
5 VAL A  61
PHE A 141
VAL A  55
LEU A 117
ILE A  39
None
1.04A 3w67D-6allA:
undetectable
3w67D-6allA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN


(Campylobacter
jejuni)
no annotation 5 VAL A 132
ILE A  86
LEU A 156
ILE A 183
LEU A 180
None
0.98A 3w67D-6b2wA:
1.2
3w67D-6b2wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c3p ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8


(Homo sapiens)
no annotation 5 PHE E1392
ILE E1344
ILE E1501
PHE E1495
LEU E1417
None
1.26A 3w67D-6c3pE:
undetectable
3w67D-6c3pE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6co7 PREDICTED PROTEIN

(Nematostella
vectensis)
no annotation 5 VAL A 308
ILE A 315
ILE A 392
VAL A 394
ILE A 354
None
1.07A 3w67D-6co7A:
undetectable
3w67D-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fai ESSENTIAL NUCLEAR
PROTEIN 1


(Saccharomyces
cerevisiae)
no annotation 5 LEU i 359
VAL i 326
LEU i 325
PHE i 323
LEU i 299
None
None
None
None
U  21269 ( 4.5A)
1.29A 3w67D-6faii:
undetectable
3w67D-6faii:
undetectable