SIMILAR PATTERNS OF AMINO ACIDS FOR 3W67_A_VIVA301_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a3x | PYRUVATE KINASE (Saccharomycescerevisiae) |
PF00224(PK)PF02887(PK_C) | 5 | ILE A 215ILE A 224VAL A 227LEU A 228VAL A 203 | None | 0.85A | 3w67A-1a3xA:2.3 | 3w67A-1a3xA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1avo | 11S REGULATOR11S REGULATOR (Homo sapiens;Homo sapiens) |
PF02251(PA28_alpha)PF02252(PA28_beta) | 5 | LEU A 40ILE B 174ILE B 121VAL B 124LEU B 167 | None | 1.09A | 3w67A-1avoA:undetectable | 3w67A-1avoA:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bhg | BETA-GLUCURONIDASE (Homo sapiens) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 5 | LEU A 373PHE A 343ILE A 629VAL A 348LEU A 585 | None | 1.15A | 3w67A-1bhgA:1.0 | 3w67A-1bhgA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c8o | ICE INHIBITOR (Cowpox virus) |
PF00079(Serpin) | 5 | ILE A 18ILE A 23VAL A 26LEU A 27VAL A 258 | None | 1.03A | 3w67A-1c8oA:undetectable | 3w67A-1c8oA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cyn | PEPTIDYL-PROLYLCIS-TRANS ISOMERASEB (Homo sapiens) |
PF00160(Pro_isomerase) | 5 | PHE A 30ILE A 167VAL A 165LEU A 18VAL A 146 | None | 0.96A | 3w67A-1cynA:undetectable | 3w67A-1cynA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e32 | P97 (Mus musculus) |
PF00004(AAA)PF02359(CDC48_N)PF02933(CDC48_2) | 5 | SER A 40LEU A 41ILE A 70VAL A 57VAL A 88 | None | 1.15A | 3w67A-1e32A:2.4 | 3w67A-1e32A:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gka | CRUSTACYANIN A2SUBUNIT (Homarusgammarus) |
PF00061(Lipocalin) | 5 | SER B 49PHE B 133ILE B 93VAL B 43VAL B 164 | NoneNoneAXT B1175 (-4.7A)NoneNone | 1.00A | 3w67A-1gkaB:undetectable | 3w67A-1gkaB:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1itz | TRANSKETOLASE (Zea mays) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | TRP A 186LEU A 146ILE A 429ILE A 433VAL A 383 | None | 1.06A | 3w67A-1itzA:undetectable | 3w67A-1itzA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqe | HISTAMINEN-METHYLTRANSFERASE (Homo sapiens) |
PF13489(Methyltransf_23) | 5 | ILE A 142ILE A 70VAL A 74LEU A 71VAL A 111 | SAH A 400 (-4.1A)NoneNoneNoneNone | 1.08A | 3w67A-1jqeA:undetectable | 3w67A-1jqeA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jzo | THIOL:DISULFIDEINTERCHANGE PROTEINDSBC (Escherichiacoli) |
PF10411(DsbC_N)PF13098(Thioredoxin_2) | 5 | SER A 101LEU A 104ILE A 139VAL A 92VAL A 179 | None | 0.94A | 3w67A-1jzoA:undetectable | 3w67A-1jzoA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lcy | HTRA2 SERINEPROTEASE (Homo sapiens) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | LEU A 205ILE A 31ILE A 60VAL A 54LEU A 59 | None | 1.14A | 3w67A-1lcyA:undetectable | 3w67A-1lcyA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m93 | SERINE PROTEINASEINHIBITOR 2SERINE PROTEINASEINHIBITOR 2 (Cowpox virus;Cowpox virus) |
PF00079(Serpin)PF00079(Serpin) | 5 | ILE A 18ILE A 23VAL A 26LEU A 27VAL B 258 | None | 0.94A | 3w67A-1m93A:undetectable | 3w67A-1m93A:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oed | ACETYLCHOLINERECEPTOR PROTEIN,ALPHA CHAIN (Torpedomarmorata) |
PF02932(Neur_chan_memb) | 5 | SER A 248LEU A 250SER A 252VAL A 232LEU A 235 | None | 1.16A | 3w67A-1oedA:undetectable | 3w67A-1oedA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pyt | CHYMOTRYPSINOGEN C (Bos taurus) |
PF00089(Trypsin) | 5 | ILE D 938ILE D 747VAL D 820LEU D 746VAL D 812 | None | 1.04A | 3w67A-1pytD:undetectable | 3w67A-1pytD:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r4p | SHIGA-LIKE TOXINTYPE II A SUBUNIT (Escherichiacoli) |
PF00161(RIP) | 5 | SER A 134LEU A 135SER A 138VAL A 164PHE A 161 | FMT A3013 (-2.6A)NoneNoneNoneNone | 1.09A | 3w67A-1r4pA:undetectable | 3w67A-1r4pA:20.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1r5l | PROTEIN(ALPHA-TOCOPHEROLTRANSFER PROTEIN) (Homo sapiens) |
PF00650(CRAL_TRIO)PF03765(CRAL_TRIO_N) | 11 | TRP A 122SER A 136LEU A 137SER A 140PHE A 158ILE A 171ILE A 179VAL A 182LEU A 183PHE A 187VAL A 191 | NoneVIV A 301 (-3.5A)VIV A 301 ( 4.8A)VIV A 301 (-3.1A)VIV A 301 (-3.9A)NoneVIV A 301 ( 4.0A)VIV A 301 (-4.5A)NoneVIV A 301 (-3.9A)VIV A 301 (-4.7A) | 0.68A | 3w67A-1r5lA:37.7 | 3w67A-1r5lA:89.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vl4 | PMBA-RELATED PROTEIN (Thermotogamaritima) |
PF01523(PmbA_TldD) | 5 | PHE A 400ILE A 243ILE A 270LEU A 336VAL A 425 | None | 1.16A | 3w67A-1vl4A:undetectable | 3w67A-1vl4A:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1we0 | ALKYL HYDROPEROXIDEREDUCTASE C (Amphibacillusxylanus) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 5 | SER A 105ILE A 97VAL A 36PHE A 123VAL A 7 | None | 1.08A | 3w67A-1we0A:undetectable | 3w67A-1we0A:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e3d | UTP--GLUCOSE-1-PHOSPHATEURIDYLYLTRANSFERASE (Escherichiacoli) |
PF00483(NTP_transferase) | 5 | LEU A 115ILE A 42ILE A 13VAL A 133VAL A 126 | None | 1.12A | 3w67A-2e3dA:undetectable | 3w67A-2e3dA:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eja | UROPORPHYRINOGENDECARBOXYLASE (Aquifexaeolicus) |
PF01208(URO-D) | 5 | SER A 257LEU A 256ILE A 302LEU A 11VAL A 195 | None | 1.10A | 3w67A-2ejaA:undetectable | 3w67A-2ejaA:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpv | FMN-DEPENDENTNADH-AZOREDUCTASE (Enterococcusfaecalis) |
PF02525(Flavodoxin_2) | 5 | LEU A 27ILE A 180ILE A 146VAL A 99LEU A 144 | None | 1.02A | 3w67A-2hpvA:undetectable | 3w67A-2hpvA:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iy8 | PROTEIN PM0188 (Pasteurellamultocida) |
PF11477(PM0188) | 5 | ILE A 133ILE A 106LEU A 32PHE A 59VAL A 80 | None | 1.10A | 3w67A-2iy8A:undetectable | 3w67A-2iy8A:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j6e | IGM (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | SER H 62ILE H 37ILE H 48VAL H 67LEU H 82 | None | 1.09A | 3w67A-2j6eH:undetectable | 3w67A-2j6eH:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nz9 | BOTULINUM NEUROTOXINTYPE A (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07951(Toxin_R_bind_C)PF07952(Toxin_trans)PF07953(Toxin_R_bind_N) | 5 | SER A 794SER A 799ILE A 725VAL A 721LEU A 665 | None | 1.14A | 3w67A-2nz9A:undetectable | 3w67A-2nz9A:12.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o3j | UDP-GLUCOSE6-DEHYDROGENASE (Caenorhabditiselegans) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | ILE A 400VAL A 417LEU A 419PHE A 444VAL A 277 | None | 1.00A | 3w67A-2o3jA:undetectable | 3w67A-2o3jA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odp | COMPLEMENT C2 (Homo sapiens) |
PF00089(Trypsin)PF00092(VWA) | 5 | LEU A 303ILE A 391ILE A 352LEU A 235VAL A 271 | None | 1.14A | 3w67A-2odpA:undetectable | 3w67A-2odpA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p4z | METAL-DEPENDENTHYDROLASES OF THEBETA-LACTAMASESUPERFAMILY II (Caldanaerobactersubterraneus) |
PF00753(Lactamase_B) | 5 | LEU A 252SER A 221VAL A 15LEU A 38VAL A 186 | None | 1.06A | 3w67A-2p4zA:2.9 | 3w67A-2p4zA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pd3 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Helicobacterpylori) |
PF13561(adh_short_C2) | 5 | SER A 27ILE A 191VAL A 89LEU A 141PHE A 87 | NoneNAD A1780 (-4.4A)NoneNoneNone | 1.07A | 3w67A-2pd3A:2.4 | 3w67A-2pd3A:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2py6 | METHYLTRANSFERASEFKBM (Methylobacillusflagellatus) |
PF05050(Methyltransf_21) | 5 | SER A 239ILE A 236VAL A 270LEU A 267VAL A 285 | NoneNonePEG A 415 (-4.5A)NoneNone | 0.96A | 3w67A-2py6A:0.2 | 3w67A-2py6A:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uwb | CELLULASE (Tropaeolummajus) |
PF00722(Glyco_hydro_16)PF06955(XET_C) | 5 | LEU A 210SER A 212ILE A 66VAL A 175LEU A 82 | None | 1.06A | 3w67A-2uwbA:undetectable | 3w67A-2uwbA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wnb | - (Sus scrofa) |
PF00777(Glyco_transf_29) | 5 | LEU A 201ILE A 208VAL A 193PHE A 198VAL A 220 | None | 0.90A | 3w67A-2wnbA:undetectable | 3w67A-2wnbA:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xxz | LYSINE-SPECIFICDEMETHYLASE 6B (Homo sapiens) |
PF02373(JmjC) | 5 | LEU A1341ILE A1400ILE A1478VAL A1373VAL A1482 | None | 0.95A | 3w67A-2xxzA:undetectable | 3w67A-2xxzA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xzo | REGULATOR OFNONSENSE TRANSCRIPTS1 (Homo sapiens) |
PF04851(ResIII)PF13086(AAA_11)PF13087(AAA_12) | 5 | LEU A 347ILE A 381ILE A 393VAL A 411LEU A 364 | None | 0.94A | 3w67A-2xzoA:undetectable | 3w67A-2xzoA:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zhl | GALECTIN-9 (Homo sapiens) |
PF00337(Gal-bind_lectin) | 5 | LEU A 101ILE A 134VAL A 47PHE A 45VAL A 15 | None | 1.09A | 3w67A-2zhlA:undetectable | 3w67A-2zhlA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzt | PUTATIVEUNCHARACTERIZEDPROTEIN (Thermotogamaritima) |
PF16916(ZT_dimer) | 5 | ILE A 238ILE A 220VAL A 223LEU A 224VAL A 230 | None | 0.78A | 3w67A-2zztA:undetectable | 3w67A-2zztA:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3j | PBP5 (Haemophilusinfluenzae) |
PF00768(Peptidase_S11)PF07943(PBP5_C) | 5 | LEU A 66SER A 178ILE A 191ILE A 255VAL A 257 | None | 1.10A | 3w67A-3a3jA:undetectable | 3w67A-3a3jA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aq2 | 6B PROTEIN (Agrobacteriumvitis) |
PF02027(RolB_RolC) | 5 | SER A 137LEU A 56ILE A 190LEU A 81VAL A 65 | None | 1.05A | 3w67A-3aq2A:undetectable | 3w67A-3aq2A:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqp | PROBABLE SECDFPROTEIN-EXPORTMEMBRANE PROTEIN (Thermusthermophilus) |
PF02355(SecD_SecF)PF07549(Sec_GG) | 5 | SER A 638SER A 642ILE A 598VAL A 585PHE A 589 | None | 1.10A | 3w67A-3aqpA:undetectable | 3w67A-3aqpA:16.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1g | GAG POLYPROTEIN (Rous sarcomavirus) |
no annotation | 5 | SER A 163ILE A 172ILE A 219VAL A 222LEU A 223 | None | 1.13A | 3w67A-3g1gA:undetectable | 3w67A-3g1gA:17.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdn | R-OXYNITRILE LYASEISOENZYME 1 (Prunus dulcis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | LEU A 228ILE A 220VAL A 271LEU A 266VAL A 469 | None | 1.15A | 3w67A-3gdnA:undetectable | 3w67A-3gdnA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gr5 | ESCC (Escherichiacoli) |
no annotation | 5 | SER A 163LEU A 166ILE A 118LEU A 122VAL A 131 | None | 1.07A | 3w67A-3gr5A:undetectable | 3w67A-3gr5A:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kal | HOMOGLUTATHIONESYNTHETASE (Glycine max) |
PF03199(GSH_synthase)PF03917(GSH_synth_ATP) | 5 | LEU A 47SER A 50ILE A 34ILE A 435VAL A 437 | None | 1.16A | 3w67A-3kalA:undetectable | 3w67A-3kalA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3msg | INTRA-CELLULARXYLANASE IXT6 (Geobacillusstearothermophilus) |
PF00331(Glyco_hydro_10) | 5 | SER A 147ILE A 153LEU A 107PHE A 101VAL A 93 | None | 0.98A | 3w67A-3msgA:2.2 | 3w67A-3msgA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nrv | PUTATIVETRANSCRIPTIONALREGULATOR (MARR/EMRRFAMILY) (Acinetobactersp. ADP1) |
PF12802(MarR_2) | 5 | LEU A 61ILE A 35ILE A 43VAL A 45LEU A 46 | None | 1.14A | 3w67A-3nrvA:undetectable | 3w67A-3nrvA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3owa | ACYL-COADEHYDROGENASE (Bacillusanthracis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | SER A 187ILE A 236VAL A 216LEU A 237VAL A 195 | None | 1.14A | 3w67A-3owaA:undetectable | 3w67A-3owaA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pfe | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Legionellapneumophila) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | TRP A 56LEU A 189VAL A 460LEU A 464VAL A 91 | None | 1.16A | 3w67A-3pfeA:0.3 | 3w67A-3pfeA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3psq | HYPOTHETICALEXPORTED PROTEIN (Streptococcuspyogenes) |
PF04203(Sortase) | 5 | SER A 95SER A 105ILE A 63VAL A 67LEU A 60 | None | 1.07A | 3w67A-3psqA:undetectable | 3w67A-3psqA:23.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qq8 | TRANSITIONALENDOPLASMICRETICULUM ATPASE (Homo sapiens) |
PF02359(CDC48_N)PF02933(CDC48_2) | 5 | SER A 40LEU A 41ILE A 70VAL A 57VAL A 88 | None | 1.06A | 3w67A-3qq8A:undetectable | 3w67A-3qq8A:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s6p | CAPSID PROTEIN (Helicoverpaarmigera stuntvirus) |
PF03566(Peptidase_A21) | 5 | PHE A 160ILE A 187VAL A 183LEU A 186VAL A 170 | None | 1.09A | 3w67A-3s6pA:undetectable | 3w67A-3s6pA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sds | ORNITHINECARBAMOYLTRANSFERASE, MITOCHONDRIAL (Coccidioidesimmitis) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | LEU A 36ILE A 335LEU A 338PHE A 341VAL A 122 | None | 1.09A | 3w67A-3sdsA:undetectable | 3w67A-3sdsA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t66 | NICKEL ABCTRANSPORTER(NICKEL-BINDINGPROTEIN) (Bacillushalodurans) |
PF00496(SBP_bac_5) | 5 | PHE A 133ILE A 115VAL A 92LEU A 96VAL A 142 | None | 1.15A | 3w67A-3t66A:undetectable | 3w67A-3t66A:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tkn | NUCLEOPORIN NUP82 (Saccharomycescerevisiae) |
no annotation | 5 | ILE A 287ILE A 325VAL A 354LEU A 324VAL A 375 | None | 1.09A | 3w67A-3tknA:undetectable | 3w67A-3tknA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u2p | RECEPTORTYROSINE-PROTEINKINASE ERBB-4 (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain) | 5 | LEU A 111ILE A 40VAL A 62LEU A 38VAL A 34 | None | 1.06A | 3w67A-3u2pA:undetectable | 3w67A-3u2pA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u7u | RECEPTORTYROSINE-PROTEINKINASE ERBB-4 (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 5 | LEU A 111ILE A 40VAL A 62LEU A 38VAL A 34 | None | 1.06A | 3w67A-3u7uA:undetectable | 3w67A-3u7uA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u7u | RECEPTORTYROSINE-PROTEINKINASE ERBB-4 (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 5 | LEU A 111ILE A 43ILE A 40VAL A 62LEU A 38 | None | 1.10A | 3w67A-3u7uA:undetectable | 3w67A-3u7uA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vom | PUTATIVEPHOSPHOSERINEAMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF00266(Aminotran_5) | 5 | LEU A 71ILE A 221ILE A 78LEU A 79VAL A 58 | None | 1.13A | 3w67A-3vomA:undetectable | 3w67A-3vomA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3we7 | PUTATIVEUNCHARACTERIZEDPROTEIN PH0499 (Pyrococcushorikoshii) |
PF02585(PIG-L) | 5 | SER A 165SER A 169ILE A 41VAL A 140LEU A 39 | None | 1.08A | 3w67A-3we7A:undetectable | 3w67A-3we7A:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wks | O-PHOSPHO-L-SERYL-TRNA:CYS-TRNA SYNTHASE (Methanocaldococcusjannaschii) |
PF05889(SepSecS) | 5 | ILE A 197ILE A 176VAL A 119LEU A 175VAL A 108 | None | 1.08A | 3w67A-3wksA:undetectable | 3w67A-3wksA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wv6 | GALECTIN-9 (Homo sapiens) |
PF00337(Gal-bind_lectin) | 5 | LEU A 101ILE A 134VAL A 47PHE A 45VAL A 15 | None | 1.09A | 3w67A-3wv6A:undetectable | 3w67A-3wv6A:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zk4 | DIPHOSPHONUCLEOTIDEPHOSPHATASE 1 (Lupinus luteus) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 5 | ILE A 269ILE A 431VAL A 470LEU A 430VAL A 422 | None | 1.14A | 3w67A-3zk4A:3.2 | 3w67A-3zk4A:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2l | TWO-COMPONENT SYSTEMSENSOR HISTIDINEKINASE/RESPONSE (Bacteroidesthetaiotaomicron) |
PF07494(Reg_prop)PF07495(Y_Y_Y) | 5 | SER A 355LEU A 354ILE A 422ILE A 408VAL A 359 | None | 1.13A | 3w67A-4a2lA:undetectable | 3w67A-4a2lA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a3x | EPA1P ([Candida]glabrata) |
PF10528(GLEYA) | 5 | LEU A 207PHE A 248ILE A 219VAL A 169LEU A 221 | None | 0.96A | 3w67A-4a3xA:undetectable | 3w67A-4a3xA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4asl | EPA1P ([Candida]glabrata) |
PF10528(GLEYA) | 5 | LEU A 207PHE A 248ILE A 219VAL A 169LEU A 221 | None | 1.00A | 3w67A-4aslA:undetectable | 3w67A-4aslA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cca | SYNTAXIN-BINDINGPROTEIN 2 (Homo sapiens) |
PF00995(Sec1) | 5 | LEU A 364ILE A 389VAL A 392LEU A 393VAL A 431 | None | 1.04A | 3w67A-4ccaA:undetectable | 3w67A-4ccaA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fie | SERINE/THREONINE-PROTEIN KINASE PAK 4 (Homo sapiens) |
PF00069(Pkinase)PF00786(PBD) | 5 | LEU A 535ILE A 527ILE A 503VAL A 505VAL A 407 | None | 1.02A | 3w67A-4fieA:undetectable | 3w67A-4fieA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h3s | GLUTAMINE-TRNALIGASE (Saccharomycescerevisiae) |
PF00749(tRNA-synt_1c)PF03950(tRNA-synt_1c_C)PF04557(tRNA_synt_1c_R2) | 5 | PHE A 315ILE A 534ILE A 538VAL A 543PHE A 223 | None | 1.13A | 3w67A-4h3sA:undetectable | 3w67A-4h3sA:16.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hpf | POTASSIUM CHANNELSUBFAMILY U MEMBER 1 (Homo sapiens) |
PF03493(BK_channel_a) | 5 | TRP A 464ILE A 446ILE A 473LEU A 478VAL A 927 | None | 1.11A | 3w67A-4hpfA:undetectable | 3w67A-4hpfA:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ic6 | PROTEASE DO-LIKE 8,CHLOROPLASTIC (Arabidopsisthaliana) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | ILE A 262ILE A 304VAL A 232LEU A 303VAL A 158 | None | 1.16A | 3w67A-4ic6A:undetectable | 3w67A-4ic6A:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4inz | SOLUBLE EPOXIDEHYDROLASE (Bacillusmegaterium) |
PF00561(Abhydrolase_1) | 5 | LEU A 117ILE A 72ILE A 102VAL A 95LEU A 27 | None | 0.98A | 3w67A-4inzA:undetectable | 3w67A-4inzA:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jbh | ALCOHOLDEHYDROGENASE (ZINC) (Pyrobaculumaerophilum) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | SER A 203LEU A 205SER A 207VAL A 324PHE A 301 | None | 1.02A | 3w67A-4jbhA:undetectable | 3w67A-4jbhA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kh9 | HYPOTHETICAL PROTEIN (Legionellapneumophila) |
PF16024(DUF4785) | 5 | SER A 311ILE A 370VAL A 378LEU A 369VAL A 305 | None | 1.08A | 3w67A-4kh9A:undetectable | 3w67A-4kh9A:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4leo | RECEPTORTYROSINE-PROTEINKINASE ERBB-3 (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 5 | LEU C 117ILE C 46VAL C 68LEU C 44VAL C 40 | None | 0.99A | 3w67A-4leoC:undetectable | 3w67A-4leoC:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7c | TELOMERICREPEAT-BINDINGFACTOR 2 (Homo sapiens) |
PF08558(TRF) | 5 | PHE A 217ILE A 177ILE A 133VAL A 135LEU A 136 | None | 1.09A | 3w67A-4m7cA:0.9 | 3w67A-4m7cA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mks | ENOLASE 2 (Lactobacillusgasseri) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 112SER A 115ILE A 336ILE A 338LEU A 380 | None | 1.07A | 3w67A-4mksA:undetectable | 3w67A-4mksA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mow | GLUCOSE1-DEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 5 | SER A 230LEU A 4ILE A 182ILE A 137VAL A 87 | None | 1.16A | 3w67A-4mowA:2.4 | 3w67A-4mowA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nem | INTERLEUKIN-2 (Homo sapiens) |
PF00715(IL2) | 5 | SER A 125PHE A 117ILE A 28ILE A 24VAL A 93 | None | 1.14A | 3w67A-4nemA:undetectable | 3w67A-4nemA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q4a | UNCHARACTERIZED ABCTRANSPORTERATP-BINDING PROTEINTM_0288 (Thermotogamaritima) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 5 | SER B 426LEU B 427SER B 430ILE B 417VAL B 414 | None | 1.01A | 3w67A-4q4aB:undetectable | 3w67A-4q4aB:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r86 | RND FAMILYAMINOGLYCOSIDE/MULTIDRUG EFFLUX PUMP (Salmonellaenterica) |
PF00873(ACR_tran) | 5 | LEU A 154ILE A 180ILE A 173VAL A 169LEU A 217 | None | 1.15A | 3w67A-4r86A:undetectable | 3w67A-4r86A:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4txw | HYALURONOGLUCOSAMINIDASE (Clostridiumperfringens) |
PF00754(F5_F8_type_C) | 5 | ILE A 82ILE A 67VAL A 131LEU A 69VAL A 47 | None | 1.15A | 3w67A-4txwA:undetectable | 3w67A-4txwA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u4l | BETA-LACTAMASE NDM-1 (Klebsiellapneumoniae) |
PF00753(Lactamase_B) | 5 | LEU A 180ILE A 109ILE A 79VAL A 89VAL A 247 | None | 0.99A | 3w67A-4u4lA:2.4 | 3w67A-4u4lA:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4us4 | TRANSPORTER (Bacillushalodurans) |
PF00209(SNF) | 5 | LEU A 291SER A 36PHE A 313ILE A 299PHE A 275 | None | 0.99A | 3w67A-4us4A:undetectable | 3w67A-4us4A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgc | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 5 (Drosophilamelanogaster) |
PF13191(AAA_16)PF14630(ORC5_C) | 5 | LEU E 84ILE E 26ILE E 156VAL E 125LEU E 157 | None | 1.06A | 3w67A-4xgcE:2.0 | 3w67A-4xgcE:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z8s | RRNA N-GLYCOSIDASE (Momordicacharantia) |
PF00161(RIP) | 5 | LEU A 54ILE A 114ILE A 155VAL A 158LEU A 159 | None | 0.94A | 3w67A-4z8sA:undetectable | 3w67A-4z8sA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csl | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF01039(Carboxyl_trans)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2)PF08326(ACC_central) | 5 | SER A1191LEU A1194SER A1193ILE A1245VAL A1180 | None | 0.95A | 3w67A-5cslA:2.7 | 3w67A-5cslA:8.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eb5 | HNL ISOENZYME 5 (Prunus dulcis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | LEU A 229ILE A 220VAL A 272LEU A 267VAL A 470 | None | 1.10A | 3w67A-5eb5A:1.0 | 3w67A-5eb5A:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey9 | LONG-CHAIN-FATTY-ACID--AMP LIGASE FADD32 (Mycobacteriummarinum) |
PF00501(AMP-binding) | 5 | LEU A 486ILE A 402ILE A 416LEU A 370VAL A 386 | None | 1.03A | 3w67A-5ey9A:undetectable | 3w67A-5ey9A:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f5o | NUCLEOPROTEIN (Marburgmarburgvirus) |
PF05505(Ebola_NP) | 5 | LEU A 140SER A 217ILE A 42ILE A 182VAL A 158 | None | 1.07A | 3w67A-5f5oA:0.8 | 3w67A-5f5oA:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxd | TUMOR NECROSISFACTOR ALPHA-INDUCEDPROTEIN 8 (Mus musculus) |
PF05527(DUF758) | 5 | LEU A 128ILE A 198ILE A 189LEU A 185VAL A 57 | NoneNone6OU A 201 ( 4.9A)NoneNone | 0.99A | 3w67A-5jxdA:undetectable | 3w67A-5jxdA:23.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ldr | BETA-D-GALACTOSIDASE (Paracoccus sp.32d) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 5 | LEU B 554ILE B 468ILE B 557PHE B 567VAL B 565 | None | 1.14A | 3w67A-5ldrB:1.7 | 3w67A-5ldrB:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5liy | ALDO-KETO REDUCTASEFAMILY 1 MEMBER B10 (Homo sapiens) |
PF00248(Aldo_ket_red) | 5 | SER X 8LEU X 7ILE X 167VAL X 107VAL X 149 | None | 1.08A | 3w67A-5liyX:1.6 | 3w67A-5liyX:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ljy | ENVELOPMENTPOLYPROTEIN (Hantaanorthohantavirus) |
PF01561(Hanta_G2) | 5 | ILE A 304ILE A 306VAL A 308LEU A 25VAL A 19 | None | 0.93A | 3w67A-5ljyA:undetectable | 3w67A-5ljyA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mkg | DIGUANYLATEPHOSPHODIESTERASE (Pseudomonasaeruginosa) |
PF00563(EAL) | 5 | LEU B 136ILE B 203VAL B 177PHE B 147VAL B 128 | None | 1.12A | 3w67A-5mkgB:2.9 | 3w67A-5mkgB:23.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mue | ALPHA-TOCOPHEROLTRANSFER PROTEIN (Homo sapiens) |
PF00650(CRAL_TRIO)PF03765(CRAL_TRIO_N) | 11 | TRP A 122SER A 136LEU A 137SER A 140PHE A 158ILE A 171ILE A 179VAL A 182LEU A 183PHE A 187VAL A 191 | NoneVIV A 302 (-3.5A)VIV A 302 ( 4.8A)VIV A 302 (-3.2A)VIV A 302 (-3.9A)VIV A 302 ( 4.8A)VIV A 302 (-4.0A)VIV A 302 (-4.4A)NoneVIV A 302 (-4.0A)VIV A 302 ( 4.9A) | 0.61A | 3w67A-5mueA:34.0 | 3w67A-5mueA:92.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o3m | PROTOCATECHUATEDECARBOXYLASE (Klebsiellapneumoniae) |
PF01977(UbiD) | 5 | LEU A 365ILE A 430ILE A 460LEU A 400VAL A 370 | None | 0.93A | 3w67A-5o3mA:undetectable | 3w67A-5o3mA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5olt | - (-) |
no annotation | 5 | LEU A 285PHE A 224VAL A 239LEU A 237PHE A 389 | None | 1.05A | 3w67A-5oltA:undetectable | 3w67A-5oltA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ttx | HYDROGENASE 2MATURATION PEPTIDASE (Thaumarchaeotaarchaeon SCGCAB-539-E09) |
PF01750(HycI) | 5 | LEU A 55PHE A 109VAL A 120LEU A 81PHE A 63 | None | 1.14A | 3w67A-5ttxA:undetectable | 3w67A-5ttxA:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xao | UNCHARACTERIZEDPROTEIN (Parastagonosporanodorum) |
PF01266(DAO) | 5 | LEU A 378ILE A 45VAL A 167LEU A 171VAL A 28 | None | 1.11A | 3w67A-5xaoA:undetectable | 3w67A-5xaoA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsq | NUCLEOPROTEIN (Marburgmarburgvirus) |
PF05505(Ebola_NP) | 5 | LEU A 124SER A 201ILE A 26ILE A 166VAL A 142 | None | 1.05A | 3w67A-5xsqA:undetectable | 3w67A-5xsqA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z5d | BETA-XYLOSIDASE (Geobacillusthermoleovorans) |
no annotation | 5 | ILE A 134ILE A 87VAL A 99LEU A 86VAL A 37 | None | 1.07A | 3w67A-5z5dA:undetectable | 3w67A-5z5dA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6czm | - (-) |
no annotation | 5 | LEU A 333SER A 336ILE A 356VAL A 276VAL A 292 | None | 1.14A | 3w67A-6czmA:undetectable | 3w67A-6czmA:undetectable |