SIMILAR PATTERNS OF AMINO ACIDS FOR 3VXI_A_ASCA502
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gah | HETEROTETRAMERICSARCOSINE OXIDASEGAMMA-SUBUNIT (Stenotrophomonasmaltophilia) |
PF04268(SoxG) | 4 | ALA C 179ASN C 120ARG C 178PRO C 177 | None | 1.41A | 3vxiA-2gahC:0.0 | 3vxiA-2gahC:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oz8 | MLL7089 PROTEIN (Mesorhizobiumjaponicum) |
PF13378(MR_MLE_C) | 4 | ALA A 338ARG A 341PRO A 119HIS A 303 | None | 1.19A | 3vxiA-2oz8A:0.0 | 3vxiA-2oz8A:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w47 | LIPOLYTIC ENZYME,G-D-S-L (Ruminiclostridiumthermocellum) |
PF16990(CBM_35) | 4 | ALA A 66ASN A 62ARG A 68PRO A 69 | NoneNoneUNF A1138 (-2.9A)None | 1.37A | 3vxiA-2w47A:undetectable | 3vxiA-2w47A:14.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ego | PROBABLE2-DEHYDROPANTOATE2-REDUCTASE (Bacillussubtilis) |
PF02558(ApbA)PF08546(ApbA_C) | 4 | ALA A 148ASN A 92ARG A 152PRO A 150 | None | 1.36A | 3vxiA-3egoA:0.0 | 3vxiA-3egoA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hpf | MUCONATECYCLOISOMERASE (Oceanobacillusiheyensis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASN A 21ARG A 15PRO A 326HIS A 23 | NoneGAE A 411 (-3.0A)NoneNone | 1.33A | 3vxiA-3hpfA:0.0 | 3vxiA-3hpfA:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3om9 | LACTATEDEHYDROGENASE (Toxoplasmagondii) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | ALA A 164ASN A 140PRO A 250HIS A 195 | NAD A 701 (-3.7A)OXQ A 702 ( 3.2A)NAD A 701 ( 4.4A)NAD A 701 ( 3.5A) | 1.45A | 3vxiA-3om9A:0.0 | 3vxiA-3om9A:19.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3vxi | DYP (Bjerkanderaadusta) |
PF04261(Dyp_perox) | 5 | ALA A 190ASN A 313ARG A 315PRO A 321HIS A 326 | ASC A 502 (-3.4A)ASC A 502 ( 3.0A)HEM A 501 ( 3.9A)ASC A 502 (-3.6A)ASC A 502 (-4.3A) | 0.01A | 3vxiA-3vxiA:73.0 | 3vxiA-3vxiA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fgv | CHROMOSOME REGIONMAINTENANCE 1 (CRM1)OR EXPORTIN 1 (XPO1) (Chaetomiumthermophilum) |
PF03810(IBN_N)PF08389(Xpo1)PF08767(CRM1_C) | 4 | ALA A 652ASN A 659ARG A 709PRO A 705 | None | 1.18A | 3vxiA-4fgvA:0.0 | 3vxiA-4fgvA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ldu | AUXIN RESPONSEFACTOR 5 (Arabidopsisthaliana) |
PF02362(B3)PF06507(Auxin_resp) | 4 | ALA A 180ARG A 178PRO A 176HIS A 221 | None | 1.18A | 3vxiA-4lduA:0.0 | 3vxiA-4lduA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nmw | PIMELYL-[ACYL-CARRIER PROTEIN] METHYLESTER ESTERASE (Salmonellaenterica) |
PF00561(Abhydrolase_1) | 4 | ALA A 167ASN A 25ARG A 52PRO A 169 | None | 1.30A | 3vxiA-4nmwA:undetectable | 3vxiA-4nmwA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uzy | FLAGELLAR ASSOCIATEDPROTEININTRAFLAGELLARTRANSPORT PROTEINIFT52 (Chlamydomonasreinhardtii;Chlamydomonasreinhardtii) |
PF12895(ANAPC3)PF13174(TPR_6)no annotation | 4 | ALA B 346ASN A 314PRO A 309HIS A 280 | None | 1.04A | 3vxiA-4uzyB:undetectable | 3vxiA-4uzyB:8.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ce5 | TRIACYLGLYCEROLLIPASE (Geobacillusthermocatenulatus) |
no annotation | 4 | ALA A 9ARG A 5PRO A 389HIS A 109 | None | 0.87A | 3vxiA-5ce5A:undetectable | 3vxiA-5ce5A:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d6o | HOMOSERINEO-ACETYLTRANSFERASE (Corynebacteriumglutamicum) |
PF00561(Abhydrolase_1) | 4 | ALA A 39ASN A 87PRO A 14HIS A 62 | GOL A 409 ( 3.7A)NoneGOL A 409 ( 3.9A)GOL A 409 ( 4.7A) | 1.39A | 3vxiA-5d6oA:undetectable | 3vxiA-5d6oA:23.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5do7 | ATP-BINDING CASSETTESUB-FAMILY G MEMBER5 (Homo sapiens) |
PF00005(ABC_tran)PF01061(ABC2_membrane) | 4 | ALA A 478ASN A 437ARG A 389HIS A 510 | None | 1.46A | 3vxiA-5do7A:undetectable | 3vxiA-5do7A:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gr1 | 1,4-ALPHA-GLUCANBRANCHING ENZYMEGLGB (Cyanothece sp.ATCC 51142) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C)PF02922(CBM_48) | 4 | ALA A 389ASN A 405ARG A 408HIS A 388 | NoneNoneGLC A 802 (-4.1A)None | 1.42A | 3vxiA-5gr1A:undetectable | 3vxiA-5gr1A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h9p | GALECTIN-3 (Homo sapiens) |
PF00337(Gal-bind_lectin) | 4 | ALA A 146ARG A 144PRO A 161HIS A 158 | TD2 A 301 (-3.2A)TD2 A 301 (-3.5A)NoneTD2 A 301 (-3.8A) | 1.06A | 3vxiA-5h9pA:undetectable | 3vxiA-5h9pA:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5joz | NON-REDUCING ENDALPHA-L-ARABINOFURANOSIDASE BOGH43B (Bacteroidesovatus) |
PF04616(Glyco_hydro_43) | 4 | ALA A 78ASN A 84ARG A 81PRO A 59 | None | 1.17A | 3vxiA-5jozA:undetectable | 3vxiA-5jozA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xge | UNCHARACTERIZEDPROTEIN PA0861 (Pseudomonasaeruginosa) |
no annotation | 4 | ALA A 395ASN A 463ARG A 401HIS A 406 | None | 0.88A | 3vxiA-5xgeA:1.7 | 3vxiA-5xgeA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6am0 | KLLA0F23980PKLLA0A01474P (Kluyveromyceslactis;Kluyveromyceslactis) |
no annotationno annotation | 4 | ALA C 362ARG A 39PRO A 30HIS A 43 | None | 0.93A | 3vxiA-6am0C:undetectable | 3vxiA-6am0C:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fay | ODZ3 PROTEIN (Mus musculus) |
no annotation | 4 | ASN A2168ARG A2166PRO A2188HIS A2176 | None | 1.47A | 3vxiA-6fayA:undetectable | 3vxiA-6fayA:undetectable |