SIMILAR PATTERNS OF AMINO ACIDS FOR 3VWR_A_ACAA601_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d6s O-ACETYLSERINE
SULFHYDRYLASE

(Salmonella
enterica) 		PF00291
(PALP) 		5 ALA A  75
SER A  39
ASN A  71
GLY A  45
ILE A  44
 None
None
PLP  A 501 ( 3.9A)
None
None
 1.10A 3vwrA-1d6sA:
undetectable		 3vwrA-1d6sA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bxy MALTOOLIGOSYLTREHALO
SE TREHALOHYDROLASE

(Deinococcus
radiodurans) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48)
PF11941
(DUF3459) 		5 MET A 262
ALA A 260
TYR A 215
PHE A 269
GLY A 258
 None
 1.05A 3vwrA-2bxyA:
0.0		 3vwrA-2bxyA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9i RHAMNULOSE-1-PHOSPHA
TE ALDOLASE

(Escherichia
coli) 		PF00596
(Aldolase_II) 		5 MET A 140
ASP A  26
ASN A  32
GLY A 216
ILE A 228
 None
 1.40A 3vwrA-2v9iA:
0.0		 3vwrA-2v9iA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vgq SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,MITOCHONDRIA
L
ANTIVIRAL-SIGNALING
PROTEIN

(Escherichia
coli;
Homo sapiens) 		PF13416
(SBP_bac_8)
PF16739
(CARD_2) 		5 ALA A 231
ASP A 296
TYR A 210
ASN A 234
GLY A 228
 None
None
None
SO4  A1467 (-3.5A)
None
 1.30A 3vwrA-2vgqA:
undetectable		 3vwrA-2vgqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wk8 CAI-1 AUTOINDUCER
SYNTHASE

(Vibrio cholerae) 		PF00155
(Aminotran_1_2) 		5 ALA A 111
ASP A 173
SER A 135
ASN A 112
GLY A 243
 None
PLP  A 600 (-3.5A)
PLP  A 600 ( 3.8A)
PLP  A 600 ( 4.7A)
None
 1.37A 3vwrA-2wk8A:
0.0		 3vwrA-2wk8A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xz3 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ENVELOPE
GLYCOPROTEIN

(Bovine leukemia
virus;
Escherichia
coli) 		PF00429
(TLV_coat)
PF13416
(SBP_bac_8) 		5 ALA A 257
ASP A 322
TYR A 236
ASN A 260
GLY A 254
 None
 1.29A 3vwrA-2xz3A:
0.0		 3vwrA-2xz3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ze3 DFA0005

(Deinococcus
ficus) 		PF13714
(PEP_mutase) 		5 ALA A 226
PHE A 186
ASN A 208
GLY A 225
ILE A 196
 None
AKG  A 276 ( 4.8A)
None
None
None
 1.48A 3vwrA-2ze3A:
0.0		 3vwrA-2ze3A:
23.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE

(Flavobacterium
sp.) 		PF00144
(Beta-lactamase) 		7 MET A 111
LYS A 115
TRP A 186
TYR A 215
SER A 217
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-3.1A)
MES  A 504 (-4.0A)
GOL  A 505 ( 4.4A)
MES  A 504 ( 2.7A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.19A 3vwrA-2zm2A:
68.7		 3vwrA-2zm2A:
97.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a3c MALTOSE-BINDING
PERIPLASMIC PROTEIN,
LINKER,
MITOCHONDRIAL
INTERMEMBRANE SPACE
IMPORT AND ASSEMBLY
PROTEIN 40

(Escherichia
coli;
Saccharomyces
cerevisiae;
synthetic
construct) 		PF06747
(CHCH)
PF13416
(SBP_bac_8) 		5 ALA A 231
ASP A 296
TYR A 210
ASN A 234
GLY A 228
 None
 1.28A 3vwrA-3a3cA:
0.0		 3vwrA-3a3cA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce6 ADENOSYLHOMOCYSTEINA
SE

(Mycobacterium
tuberculosis) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		5 MET A 352
ALA A 351
PHE A 392
GLY A 329
ILE A 328
 None
 1.37A 3vwrA-3ce6A:
undetectable		 3vwrA-3ce6A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cih PUTATIVE
ALPHA-RHAMNOSIDASE

(Bacteroides
thetaiotaomicron) 		PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		5 MET A 322
TYR A 300
PHE A 330
GLY A 318
ILE A 629
 None
 1.43A 3vwrA-3cihA:
undetectable		 3vwrA-3cihA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d54 PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE 1

(Thermotoga
maritima) 		PF13507
(GATase_5) 		5 MET D 184
ALA D 171
SER D 166
ASN D 164
GLY D 172
 CYG  D  86 ( 3.4A)
None
None
None
None
 1.35A 3vwrA-3d54D:
undetectable		 3vwrA-3d54D:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ehs FUSION PROTEIN OF
CRFR1 EXTRACELLULAR
DOMAIN AND MBP

(Escherichia
coli;
Homo sapiens) 		PF02793
(HRM)
PF13416
(SBP_bac_8) 		5 ALA A-118
ASP A -53
TYR A-139
ASN A-115
GLY A-121
 None
 1.29A 3vwrA-3ehsA:
undetectable		 3vwrA-3ehsA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f5f MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HEPARAN SULFATE
2-O-SULFOTRANSFERASE
1

(Escherichia
coli;
Gallus gallus) 		PF03567
(Sulfotransfer_2)
PF13416
(SBP_bac_8) 		5 ALA A 231
ASP A 296
TYR A 210
ASN A 234
GLY A 228
 None
 1.30A 3vwrA-3f5fA:
undetectable		 3vwrA-3f5fA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4z MALTOSE-BINDING
PERIPLASMIC PROTEIN
FUSED WITH ALLERGEN
DERP7

(Dermatophagoides
pteronyssinus;
Escherichia
coli) 		PF13416
(SBP_bac_8)
PF16984
(Grp7_allergen) 		5 ALA A 231
ASP A 296
TYR A 210
ASN A 234
GLY A 228
 None
NA  A1216 ( 3.8A)
None
None
None
 1.29A 3vwrA-3h4zA:
undetectable		 3vwrA-3h4zA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA

(Homo sapiens) 		PF02793
(HRM)
PF13416
(SBP_bac_8) 		5 ALA A-139
ASP A -74
TYR A-160
ASN A-136
GLY A-142
 None
 1.30A 3vwrA-3n93A:
undetectable		 3vwrA-3n93A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n94 FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PITUITARY
ADENYLATE CYCLASE 1
RECEPTOR-SHORT

(Escherichia
coli;
Homo sapiens) 		PF02793
(HRM)
PF13416
(SBP_bac_8) 		5 ALA A-117
ASP A -52
TYR A-138
ASN A-114
GLY A-120
 None
 1.32A 3vwrA-3n94A:
undetectable		 3vwrA-3n94A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pef 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
NAD-BINDING

(Geobacter
metallireducens) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		5 MET A 211
ALA A 212
ASN A 213
GLY A 209
ILE A 206
 None
GOL  A 290 (-3.7A)
None
None
GOL  A 290 ( 4.7A)
 1.20A 3vwrA-3pefA:
undetectable		 3vwrA-3pefA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rr2 CYSTEINE SYNTHASE

(Mycobacterium
marinum) 		PF00291
(PALP) 		5 ALA A  78
SER A  42
ASN A  74
GLY A  48
ILE A  47
 None
 1.20A 3vwrA-3rr2A:
undetectable		 3vwrA-3rr2A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1j SERINE PROTEASE NS3

(Dengue virus) 		PF00949
(Peptidase_S7) 		5 ALA B 166
SER B 163
PHE B 116
GLY B 148
ILE B 139
 None
 1.50A 3vwrA-3u1jB:
undetectable		 3vwrA-3u1jB:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v39 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE

(Bdellovibrio
bacteriovorus) 		PF02113
(Peptidase_S13) 		5 ALA A  69
PHE A 286
ASN A 303
GLY A 359
ILE A  71
 TAU  A 501 (-3.4A)
None
None
TAU  A 501 (-3.5A)
None
 1.44A 3vwrA-3v39A:
12.5		 3vwrA-3v39A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zei O-ACETYLSERINE
SULFHYDRYLASE

(Mycobacterium
tuberculosis) 		PF00291
(PALP) 		5 ALA A  78
SER A  42
ASN A  74
GLY A  48
ILE A  47
 None
None
PLP  A1301 (-3.8A)
None
None
 1.15A 3vwrA-3zeiA:
undetectable		 3vwrA-3zeiA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1

(Escherichia
coli;
Homo sapiens) 		PF00619
(CARD)
PF13416
(SBP_bac_8) 		5 ALA A 232
ASP A 297
TYR A 211
ASN A 235
GLY A 229
 None
 1.30A 3vwrA-4ifpA:
undetectable		 3vwrA-4ifpA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k90 EXTRACELLULAR
METALLOPROTEINASE
MEP

(Aspergillus
fumigatus) 		PF02128
(Peptidase_M36) 		5 ALA A 396
ASP A 386
ASN A 394
GLY A 404
ILE A 381
 None
 1.36A 3vwrA-4k90A:
undetectable		 3vwrA-4k90A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kv3 CHIMERA FUSION
PROTEIN OF ESX-1
SECRETION SYSTEM
PROTEIN ECCD1 AND
MALTOSE-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli;
Mycobacterium
tuberculosis) 		PF08817
(YukD)
PF13416
(SBP_bac_8) 		5 ALA A 232
ASP A 297
TYR A 211
ASN A 235
GLY A 229
 None
 1.30A 3vwrA-4kv3A:
undetectable		 3vwrA-4kv3A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4li3 CYSTEINE SYNTHASE

(Haemophilus
influenzae) 		PF00291
(PALP) 		5 ALA X  76
SER X  40
ASN X  72
GLY X  46
ILE X  45
 LLP  X  42 ( 3.2A)
LLP  X  42 ( 3.0A)
LLP  X  42 ( 3.8A)
LLP  X  42 ( 3.7A)
LLP  X  42 ( 4.0A)
 1.05A 3vwrA-4li3X:
undetectable		 3vwrA-4li3X:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lma CYSTEINE SYNTHASE

(Microcystis
aeruginosa) 		PF00291
(PALP) 		5 ALA A  81
SER A  44
ASN A  77
GLY A  50
ILE A  49
 None
PLP  A 403 ( 4.7A)
PLP  A 403 (-3.9A)
None
None
 1.08A 3vwrA-4lmaA:
undetectable		 3vwrA-4lmaA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lmb CYSTEINE SYNTHASE

(Microcystis
aeruginosa) 		PF00291
(PALP) 		5 ALA A  81
SER A  44
ASN A  77
GLY A  50
ILE A  49
 None
None
PLP  A 403 ( 3.7A)
None
None
 1.12A 3vwrA-4lmbA:
undetectable		 3vwrA-4lmbA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pe2 MALTOSE ABC
TRANSPORTER
PERIPLASMIC
PROTEIN,PREPILIN-TYP
E N-TERMINAL
CLEAVAGE/METHYLATION
DOMAIN PROTEIN

(Clostridioides
difficile;
Escherichia
coli) 		PF13416
(SBP_bac_8) 		5 ALA A 231
ASP A 296
TYR A 210
ASN A 234
GLY A 228
 None
 1.36A 3vwrA-4pe2A:
undetectable		 3vwrA-4pe2A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqk MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
TRUNCATED
REPLICATION PROTEIN
REPA

(Escherichia
coli;
Staphylococcus
aureus) 		PF13416
(SBP_bac_8) 		5 ALA A 232
ASP A 297
TYR A 211
ASN A 235
GLY A 229
 None
 1.32A 3vwrA-4pqkA:
undetectable		 3vwrA-4pqkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qfh GLUCOSE-6-PHOSPHATE
ISOMERASE

(Trypanosoma
cruzi) 		PF00342
(PGI) 		5 MET A 489
ASP A 103
TYR A 381
GLY A 524
ILE A  72
 None
 1.34A 3vwrA-4qfhA:
undetectable		 3vwrA-4qfhA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qsz MALTOSE-BINDING
PERIPLASMIC PROTEIN,
JMJC
DOMAIN-CONTAINING
PROTEIN 7 CHIMERA

(Escherichia
coli;
Mus musculus) 		PF13416
(SBP_bac_8)
PF13621
(Cupin_8) 		5 ALA A-140
ASP A -75
TYR A-161
ASN A-137
GLY A-143
 None
 1.30A 3vwrA-4qszA:
undetectable		 3vwrA-4qszA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wvi MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SIGNAL
PEPTIDASE IB

(Escherichia
coli;
Staphylococcus
aureus) 		PF00717
(Peptidase_S24)
PF13416
(SBP_bac_8) 		5 ALA A 237
ASP A 302
TYR A 216
ASN A 240
GLY A 234
 None
 1.30A 3vwrA-4wviA:
undetectable		 3vwrA-4wviA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cer BD0816

(Bdellovibrio
bacteriovorus) 		PF02113
(Peptidase_S13) 		5 ALA A  57
PHE A 274
ASN A 291
GLY A 347
ILE A  59
 None
 1.42A 3vwrA-5cerA:
12.7		 3vwrA-5cerA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cxo EPOXIDE HYDROLASE

(Streptomyces
albus) 		PF12680
(SnoaL_2) 		5 MET A  87
ALA A  61
ASP A  38
SER A  57
ASN A  58
 P6G  A 202 (-3.1A)
None
P6G  A 202 (-3.8A)
P6G  A 202 (-3.2A)
P6G  A 202 (-3.2A)
 1.13A 3vwrA-5cxoA:
undetectable		 3vwrA-5cxoA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dfm MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TELOMERASE-A
SSOCIATED PROTEIN 19

(Escherichia
coli;
Tetrahymena
thermophila) 		PF13416
(SBP_bac_8) 		5 ALA A 231
ASP A 296
TYR A 210
ASN A 234
GLY A 228
 None
 1.29A 3vwrA-5dfmA:
undetectable		 3vwrA-5dfmA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsg MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HANTAVIRUS
NUCLEOPROTEIN

(Hantaan
orthohantavirus) 		PF00846
(Hanta_nucleocap)
PF13416
(SBP_bac_8) 		5 ALA A-141
ASP A -76
TYR A-162
ASN A-138
GLY A-144
 None
 1.26A 3vwrA-5fsgA:
undetectable		 3vwrA-5fsgA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7n NLRP12-PYD WITH MBP
TAG

(Homo sapiens) 		PF02758
(PYRIN)
PF13416
(SBP_bac_8) 		5 ALA A 232
ASP A 297
TYR A 211
ASN A 235
GLY A 229
 None
 1.29A 3vwrA-5h7nA:
undetectable		 3vwrA-5h7nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens) 		PF11386
(VERL)
PF13416
(SBP_bac_8) 		5 ALA A3898
ASP A3963
TYR A3877
ASN A3901
GLY A3895
 None
 1.28A 3vwrA-5ii5A:
undetectable		 3vwrA-5ii5A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jj4 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SINGLE-STRAN
DED DNA CYTOSINE
DEAMINASE

(Escherichia
coli;
Homo sapiens) 		no annotation 5 ALA C 231
ASP C 296
TYR C 210
ASN C 234
GLY C 228
 None
 1.32A 3vwrA-5jj4C:
undetectable		 3vwrA-5jj4C:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jy7 MALTOKINASE

(Mycolicibacterium
smegmatis) 		PF01636
(APH) 		5 MET I 192
ASP I 321
SER I 132
ASN I 133
GLY I 191
 None
 1.32A 3vwrA-5jy7I:
undetectable		 3vwrA-5jy7I:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93

(Porphyromonas
gingivalis) 		no annotation 5 MET A 554
ALA A 553
ASN A 490
GLY A 565
ILE A 551
 None
None
ZN  A 805 ( 4.8A)
None
None
 1.40A 3vwrA-5m11A:
undetectable		 3vwrA-5m11A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xa2 CYSTEINE SYNTHASE

(Planctopirus
limnophila) 		PF00291
(PALP) 		5 ALA A  78
SER A  42
ASN A  74
GLY A  48
ILE A  47
 LLP  A  44 ( 3.2A)
LLP  A  44 ( 3.1A)
LLP  A  44 ( 3.8A)
LLP  A  44 ( 3.7A)
LLP  A  44 ( 4.1A)
 1.14A 3vwrA-5xa2A:
undetectable		 3vwrA-5xa2A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN

(Escherichia
coli) 		no annotation 5 ALA A 232
ASP A 297
TYR A 211
ASN A 235
GLY A 229
 None
 1.34A 3vwrA-5z0rA:
undetectable		 3vwrA-5z0rA:
11.28