SIMILAR PATTERNS OF AMINO ACIDS FOR 3VT7_A_VDXA500

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a9n SPLICEOSOMAL U2B''
U2A'

(Homo sapiens) 		PF00076
(RRM_1)
PF14580
(LRR_9) 		5 TYR B  31
LEU A  70
VAL A  71
ARG A  27
LEU A  37
 None
 1.30A 3vt7A-1a9nB:
undetectable		 3vt7A-1a9nB:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a9n SPLICEOSOMAL U2B''
U2A'

(Homo sapiens) 		PF00076
(RRM_1)
PF14580
(LRR_9) 		5 TYR B  31
LEU A  70
VAL A  71
SER A  50
ARG A  27
 None
 1.47A 3vt7A-1a9nB:
undetectable		 3vt7A-1a9nB:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fiu TYPE II RESTRICTION
ENZYME NGOMI

(Neisseria
gonorrhoeae) 		PF09015
(NgoMIV_restric) 		5 LEU A 205
VAL A 217
HIS A 215
LEU A 284
HIS A 181
 None
 1.47A 3vt7A-1fiuA:
0.0		 3vt7A-1fiuA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hcy ARTHROPODAN
HEMOCYANIN

(Panulirus
interruptus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		5 SER A 330
SER A 334
HIS A 384
LEU A 383
HIS A 348
 None
None
CU  A 666 (-3.4A)
None
CU  A 666 (-3.8A)
 1.46A 3vt7A-1hcyA:
0.0		 3vt7A-1hcyA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ihp PHYTASE

(Aspergillus
ficuum) 		PF00328
(His_Phos_2) 		5 LEU A 113
SER A 116
ARG A 383
SER A 382
LEU A 187
 None
 1.06A 3vt7A-1ihpA:
0.1		 3vt7A-1ihpA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kop CARBONIC ANHYDRASE

(Neisseria
gonorrhoeae) 		PF00194
(Carb_anhydrase) 		5 LEU A 122
VAL A 123
SER A 186
ARG A 171
LEU A 127
 None
 1.48A 3vt7A-1kopA:
undetectable		 3vt7A-1kopA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqs INTEGRAL MEMBRANE
PROTEIN SED5
SLY1 PROTEIN

(Saccharomyces
cerevisiae) 		PF00995
(Sec1)
PF11416
(Syntaxin-5_N) 		5 VAL A 144
SER A 145
SER B  13
VAL A 156
LEU A 132
 None
 1.41A 3vt7A-1mqsA:
0.0		 3vt7A-1mqsA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n2o PANTOTHENATE
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF02569
(Pantoate_ligase) 		5 LEU A  36
VAL A  37
SER A  65
VAL A 181
LEU A 165
 None
None
BAL  A 802 ( 4.9A)
None
None
 1.28A 3vt7A-1n2oA:
undetectable		 3vt7A-1n2oA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qpw PORCINE HEMOGLOBIN
(BETA SUBUNIT)

(Sus scrofa) 		PF00042
(Globin) 		5 TYR B 145
LEU B 141
VAL B 137
ARG B 104
VAL B  67
 None
HEM  B 750 (-4.9A)
None
None
HEM  B 750 ( 4.3A)
 1.23A 3vt7A-1qpwB:
undetectable		 3vt7A-1qpwB:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2z HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC

(Saccharomyces
cerevisiae) 		PF08123
(DOT1) 		5 TYR A 372
LEU A 376
VAL A 541
SER A 542
VAL A 383
 None
 1.41A 3vt7A-1u2zA:
undetectable		 3vt7A-1u2zA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yhu HEMOGLOBIN B2 CHAIN

(Riftia
pachyptila) 		PF00042
(Globin) 		5 LEU D  39
VAL D  35
SER D 115
ARG D 118
VAL D  58
 None
 1.43A 3vt7A-1yhuD:
undetectable		 3vt7A-1yhuD:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ar1 HYPOTHETICAL PROTEIN

(Leishmania
major) 		PF01878
(EVE) 		5 TYR A  92
VAL A 143
SER A 142
SER A  18
VAL A 109
 GOL  A 301 (-4.7A)
None
None
GOL  A 301 (-3.6A)
None
 1.35A 3vt7A-2ar1A:
undetectable		 3vt7A-2ar1A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d7i POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 10

(Homo sapiens) 		PF00535
(Glycos_transf_2)
PF00652
(Ricin_B_lectin) 		5 TYR A 276
VAL A 168
SER A 167
ARG A 171
LEU A 251
 None
 1.40A 3vt7A-2d7iA:
undetectable		 3vt7A-2d7iA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dc0 PROBABLE AMIDASE

(Thermus
thermophilus) 		PF01425
(Amidase) 		5 LEU A 288
VAL A 289
SER A 200
SER A 389
VAL A 281
 None
 1.31A 3vt7A-2dc0A:
undetectable		 3vt7A-2dc0A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8m RIBOSE 5-PHOSPHATE
ISOMERASE

(Plasmodium
falciparum) 		PF06026
(Rib_5-P_isom_A) 		5 LEU A 108
VAL A 109
SER A 112
SER A  77
LEU A  70
 None
 1.28A 3vt7A-2f8mA:
undetectable		 3vt7A-2f8mA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h21 RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E

(Pisum sativum) 		PF00856
(SET)
PF09273
(Rubis-subs-bind) 		5 VAL A 110
ARG A 134
SER A 141
VAL A 234
LEU A 219
 None
 1.03A 3vt7A-2h21A:
undetectable		 3vt7A-2h21A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h21 RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E

(Pisum sativum) 		PF00856
(SET)
PF09273
(Rubis-subs-bind) 		5 VAL A 110
SER A 113
SER A 141
VAL A 234
LEU A 219
 None
 1.13A 3vt7A-2h21A:
undetectable		 3vt7A-2h21A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hxr HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CYNR

(Escherichia
coli) 		PF03466
(LysR_substrate) 		5 VAL A 227
SER A 223
SER A 103
VAL A 168
LEU A 165
 None
 1.50A 3vt7A-2hxrA:
undetectable		 3vt7A-2hxrA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4

(Homo sapiens;
Mus musculus) 		PF04099
(Sybindin) 		5 LEU C  88
SER D 132
SER D 131
LEU D 170
HIS D 145
 None
 1.49A 3vt7A-2j3tC:
undetectable		 3vt7A-2j3tC:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jk0 L-ASPARAGINASE

(Pectobacterium
carotovorum) 		PF00710
(Asparaginase) 		5 TYR A 226
VAL A 255
SER A 256
ARG A 258
VAL A 273
 None
 1.16A 3vt7A-2jk0A:
undetectable		 3vt7A-2jk0A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k1g LIPOPROTEIN SPR

(Escherichia
coli) 		PF00877
(NLPC_P60) 		5 SER A  61
ARG A  86
VAL A 130
HIS A 131
HIS A 119
 None
 1.40A 3vt7A-2k1gA:
undetectable		 3vt7A-2k1gA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1t ENDOPLASMIN

(Canis lupus) 		PF00183
(HSP90) 		5 LEU A 640
SER A 643
ARG A 724
SER A 725
LEU A 627
 None
 1.11A 3vt7A-2o1tA:
undetectable		 3vt7A-2o1tA:
22.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2o4j VITAMIN D3 RECEPTOR

(Rattus
norvegicus) 		PF00104
(Hormone_recep) 		12 TYR A 143
TYR A 147
LEU A 229
VAL A 230
SER A 233
ARG A 270
SER A 271
SER A 274
VAL A 296
HIS A 301
LEU A 305
HIS A 393
 VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.9A)
VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 4.0A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
None
VD4  A 500 ( 3.9A)
 0.58A 3vt7A-2o4jA:
39.4		 3vt7A-2o4jA:
99.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pmi CYCLIN-DEPENDENT
PROTEIN KINASE PHO85

(Saccharomyces
cerevisiae) 		PF00069
(Pkinase) 		5 LEU A 180
VAL A 179
SER A 194
VAL A 169
LEU A 154
 None
 1.39A 3vt7A-2pmiA:
undetectable		 3vt7A-2pmiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qne PUTATIVE
METHYLTRANSFERASE

(Desulfitobacterium
hafniense) 		PF06253
(MTTB) 		5 TYR A 206
LEU A  54
VAL A  59
SER A 256
HIS A  17
 None
 1.43A 3vt7A-2qneA:
undetectable		 3vt7A-2qneA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qww TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY

(Listeria
monocytogenes) 		PF12802
(MarR_2) 		5 LEU A  83
VAL A  84
SER A 103
SER A 110
LEU A  64
 None
 1.15A 3vt7A-2qwwA:
undetectable		 3vt7A-2qwwA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rii SULFIREDOXIN-1

(Homo sapiens) 		PF02195
(ParBc) 		5 VAL X  81
SER X  95
ARG X  51
VAL X  41
HIS X  42
 None
 1.49A 3vt7A-2riiX:
undetectable		 3vt7A-2riiX:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z4g HISTIDINOL
PHOSPHATASE

(Thermus
thermophilus) 		PF02811
(PHP)
PF13263
(PHP_C) 		5 TYR A  45
LEU A  91
SER A  39
SER A 106
HIS A 150
 None
None
None
FE  A 502 ( 4.1A)
None
 1.28A 3vt7A-2z4gA:
undetectable		 3vt7A-2z4gA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zk7 GLUCOSE
1-DEHYDROGENASE
RELATED PROTEIN

(Thermoplasma
acidophilum) 		PF13561
(adh_short_C2) 		5 TYR A 108
VAL A 146
SER A 148
SER A 131
LEU A 245
 None
 1.35A 3vt7A-2zk7A:
undetectable		 3vt7A-2zk7A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3abg BILIRUBIN OXIDASE

(Albifimbria
verrucaria) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		5 SER A 272
SER A 231
SER A 198
HIS A 136
HIS A 134
 None
None
None
CU  A 701 (-3.2A)
CU  A 702 (-3.1A)
 1.28A 3vt7A-3abgA:
undetectable		 3vt7A-3abgA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bb7 INTERPAIN A

(Prevotella
intermedia) 		PF01640
(Peptidase_C10)
PF13734
(Inhibitor_I69) 		5 VAL A 320
SER A 319
SER A  77
SER A  79
LEU A  93
 None
 1.42A 3vt7A-3bb7A:
undetectable		 3vt7A-3bb7A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II

(Bartonella
henselae) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		5 ARG A 213
SER A 210
SER A  45
HIS A 347
LEU A 349
 None
 1.30A 3vt7A-3e60A:
undetectable		 3vt7A-3e60A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 ALPHA
CHAIN

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF14710
(Nitr_red_alph_N) 		5 LEU A 716
SER A 714
SER A 607
HIS A1184
HIS A1163
 None
MD1  A1245 (-3.9A)
None
MD1  A1245 ( 4.6A)
MD1  A1245 (-3.4A)
 1.40A 3vt7A-3egwA:
undetectable		 3vt7A-3egwA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fed GLUTAMATE
CARBOXYPEPTIDASE III

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		5 TYR A 575
LEU A 463
SER A 580
HIS A 637
LEU A 640
 None
 1.19A 3vt7A-3fedA:
undetectable		 3vt7A-3fedA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hzr TRYPTOPHANYL-TRNA
SYNTHETASE

(Entamoeba
histolytica) 		PF00579
(tRNA-synt_1b) 		5 TYR A 156
TYR A 211
SER A 205
VAL A 250
HIS A 253
 None
 1.42A 3vt7A-3hzrA:
undetectable		 3vt7A-3hzrA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermus
thermophilus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		5 LEU F 209
VAL F 215
SER F 214
ARG F 217
VAL F 191
 None
 1.49A 3vt7A-3kfuF:
undetectable		 3vt7A-3kfuF:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3na6 SUCCINYLGLUTAMATE
DESUCCINYLASE/ASPART
OACYLASE

(Ruegeria sp.
TM1040) 		PF04952
(AstE_AspA) 		5 TYR A 194
LEU A 205
VAL A 204
VAL A 231
HIS A 234
 None
 1.41A 3vt7A-3na6A:
undetectable		 3vt7A-3na6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwr A RUBISCO-LIKE
PROTEIN

(Paraburkholderia
fungorum) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		5 ARG A 153
SER A 373
VAL A 318
HIS A 317
HIS A 282
 None
None
None
KCX  A 195 ( 4.7A)
KCX  A 195 ( 4.6A)
 1.49A 3vt7A-3nwrA:
undetectable		 3vt7A-3nwrA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vex O-CARBAMOYLTRANSFERA
SE TOBZ

(Streptoalloteichus
tenebrarius) 		PF02543
(Carbam_trans_N)
PF16861
(Carbam_trans_C) 		5 LEU A 464
VAL A 463
SER A 460
ARG A 457
VAL A 490
 None
None
None
None
EDO  A 605 ( 4.9A)
 1.43A 3vt7A-3vexA:
undetectable		 3vt7A-3vexA:
17.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3wgp VITAMIN D3 RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		11 TYR A 143
LEU A 233
VAL A 234
SER A 237
ARG A 274
SER A 275
SER A 278
VAL A 300
HIS A 305
LEU A 309
HIS A 397
 ED9  A 501 (-3.7A)
ED9  A 501 ( 4.3A)
None
ED9  A 501 (-2.7A)
ED9  A 501 (-2.9A)
ED9  A 501 (-3.9A)
ED9  A 501 (-2.7A)
ED9  A 501 (-4.5A)
ED9  A 501 (-3.9A)
ED9  A 501 (-4.9A)
ED9  A 501 (-3.9A)
 0.21A 3vt7A-3wgpA:
36.6		 3vt7A-3wgpA:
90.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3wgp VITAMIN D3 RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		11 TYR A 143
TYR A 147
VAL A 234
SER A 237
ARG A 274
SER A 275
SER A 278
VAL A 300
HIS A 305
LEU A 309
HIS A 397
 ED9  A 501 (-3.7A)
None
None
ED9  A 501 (-2.7A)
ED9  A 501 (-2.9A)
ED9  A 501 (-3.9A)
ED9  A 501 (-2.7A)
ED9  A 501 (-4.5A)
ED9  A 501 (-3.9A)
ED9  A 501 (-4.9A)
ED9  A 501 (-3.9A)
 0.60A 3vt7A-3wgpA:
36.6		 3vt7A-3wgpA:
90.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3t DNA MISMATCH REPAIR
PROTEIN HSM3

(Saccharomyces
cerevisiae) 		no annotation 5 LEU A 380
VAL A 411
SER A 414
VAL A 349
LEU A 357
 None
 1.42A 3vt7A-4a3tA:
undetectable		 3vt7A-4a3tA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bn2 KINESIN-LIKE PROTEIN
KIF15

(Homo sapiens) 		PF00225
(Kinesin) 		5 LEU A 173
ARG A 311
VAL A 225
HIS A 223
LEU A 252
 None
 1.44A 3vt7A-4bn2A:
undetectable		 3vt7A-4bn2A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dn9 ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE

(Chloroflexus
aurantiacus) 		PF03992
(ABM) 		5 LEU A  65
VAL A  68
SER A  67
HIS A  59
LEU A   4
 None
 1.47A 3vt7A-4dn9A:
undetectable		 3vt7A-4dn9A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4je3 CENTRAL KINETOCHORE
SUBUNIT IML3

(Saccharomyces
cerevisiae) 		no annotation 5 LEU A  29
VAL A  31
ARG A  59
SER A  71
LEU A 103
 None
 1.12A 3vt7A-4je3A:
undetectable		 3vt7A-4je3A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4je3 CENTRAL KINETOCHORE
SUBUNIT IML3

(Saccharomyces
cerevisiae) 		no annotation 5 LEU A  29
VAL A  31
ARG A  59
SER A  71
VAL A  98
 None
 1.47A 3vt7A-4je3A:
undetectable		 3vt7A-4je3A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r40 PROTEIN TOLB

(Yersinia pestis) 		PF04052
(TolB_N)
PF07676
(PD40) 		5 ARG A 237
SER A 208
VAL A 195
HIS A 196
LEU A 202
 None
 1.42A 3vt7A-4r40A:
undetectable		 3vt7A-4r40A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uuc ANKYRIN REPEAT AND
SOCS BOX PROTEIN 11

(Homo sapiens) 		PF12796
(Ank_2)
PF13637
(Ank_4) 		5 LEU A 150
VAL A 149
SER A 143
SER A 141
LEU A  78
 None
 1.17A 3vt7A-4uucA:
undetectable		 3vt7A-4uucA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0b DOUBLE CLP-N MOTIF
PROTEIN

(Arabidopsis
thaliana) 		PF02861
(Clp_N) 		5 VAL A 221
SER A 224
SER A 124
VAL A 135
LEU A 115
 None
 1.35A 3vt7A-4y0bA:
undetectable		 3vt7A-4y0bA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y13 TRANSCRIPTIONAL
REGULATOR OF FTSQAZ
GENE CLUSTER

(Escherichia
coli) 		PF00196
(GerE)
PF03472
(Autoind_bind) 		5 TYR A  27
TYR A  42
LEU A 133
VAL A 158
SER A 161
 None
 1.44A 3vt7A-4y13A:
undetectable		 3vt7A-4y13A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhc STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomyces
pombe) 		no annotation 5 LEU A 686
SER A 680
SER A 658
LEU A 674
HIS A 676
 None
 1.40A 3vt7A-4yhcA:
undetectable		 3vt7A-4yhcA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yjf D-AMINO-ACID OXIDASE

(Sus scrofa) 		PF01266
(DAO) 		5 TYR B  74
TYR B 144
VAL B 157
LEU B  30
HIS B  24
 None
None
None
None
SO4  B 402 (-4.4A)
 1.48A 3vt7A-4yjfB:
undetectable		 3vt7A-4yjfB:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eow 6-HYDROXYNICOTINATE
3-MONOOXYGENASE

(Pseudomonas
putida) 		PF01494
(FAD_binding_3) 		5 LEU A 291
VAL A 290
ARG A 286
VAL A  10
LEU A 142
 None
None
None
FAD  A 401 (-4.7A)
None
 1.45A 3vt7A-5eowA:
undetectable		 3vt7A-5eowA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE

(Raoultella
terrigena) 		PF05159
(Capsule_synth) 		5 TYR A 172
TYR A 340
VAL A 302
SER A 320
LEU A 247
 None
 1.39A 3vt7A-5fa1A:
undetectable		 3vt7A-5fa1A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb4 NUP192,NUCLEOPORIN
NUP192

(Chaetomium
thermophilum) 		PF11894
(Nup192) 		5 LEU B1070
SER B1065
VAL B1114
LEU B1052
HIS B1040
 None
 1.41A 3vt7A-5hb4B:
undetectable		 3vt7A-5hb4B:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iz5 CYTOSOLIC
PHOSPHOLIPASE A2
DELTA

(Homo sapiens) 		no annotation 5 LEU B 338
SER B 363
SER B 358
HIS B 729
LEU B 683
 None
 1.31A 3vt7A-5iz5B:
undetectable		 3vt7A-5iz5B:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jx3 URACIL-DNA
GLYCOSYLASE

(Vaccinia virus) 		no annotation 5 LEU A 170
VAL A 152
HIS A 151
LEU A  57
HIS A 147
 None
 1.19A 3vt7A-5jx3A:
undetectable		 3vt7A-5jx3A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mdx PHOTOSYSTEM II CP43
REACTION CENTER
PROTEIN

(Arabidopsis
thaliana) 		PF00421
(PSII) 		5 TYR C 297
LEU C  95
VAL C 185
VAL C 176
LEU C 202
 CLA  C 503 ( 4.7A)
CLA  C 503 (-4.1A)
None
None
None
 1.23A 3vt7A-5mdxC:
undetectable		 3vt7A-5mdxC:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii) 		PF12765
(Cohesin_HEAT)
PF12830
(Nipped-B_C) 		5 TYR A1248
LEU A1241
VAL A1238
SER A1253
LEU A1198
 None
 1.37A 3vt7A-5me3A:
undetectable		 3vt7A-5me3A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5obu CHAPERONE PROTEIN
DNAK

(Mycoplasma
genitalium) 		no annotation 5 LEU A 332
VAL A 333
SER A 335
VAL A 185
LEU A 187
 None
 1.30A 3vt7A-5obuA:
undetectable		 3vt7A-5obuA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5obw CHAPERONE PROTEIN
DNAK

(Mycoplasma
genitalium) 		no annotation 5 LEU A 332
VAL A 333
SER A 335
VAL A 185
LEU A 187
 None
 1.27A 3vt7A-5obwA:
undetectable		 3vt7A-5obwA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yh1 -

(-) 		no annotation 5 TYR A 538
LEU A 496
VAL A 489
HIS A 488
HIS A 483
 None
 1.31A 3vt7A-5yh1A:
undetectable		 3vt7A-5yh1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ykn PROBABLE
LYSINE-SPECIFIC
DEMETHYLASE JMJ14

(Arabidopsis
thaliana) 		no annotation 5 LEU A 315
SER A 436
VAL A 310
HIS A 309
LEU A 362
 None
None
None
NI  A 800 (-3.5A)
None
 1.35A 3vt7A-5yknA:
undetectable		 3vt7A-5yknA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717

(Pseudoalteromonas
arctica) 		no annotation 5 SER A 378
ARG A 374
VAL A 431
HIS A 430
LEU A 165
 None
 1.45A 3vt7A-5yl7A:
undetectable		 3vt7A-5yl7A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bms PALMITOYLTRANSFERASE

(Danio rerio) 		no annotation 5 VAL A 257
SER A 272
SER A 153
SER A  68
HIS A 218
 None
 1.49A 3vt7A-6bmsA:
undetectable		 3vt7A-6bmsA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6etz BETA-GALACTOSIDASE

(Arthrobacter
sp. 32cB) 		no annotation 5 VAL A 343
ARG A 216
SER A 171
HIS A 101
LEU A  92
 None
 1.48A 3vt7A-6etzA:
undetectable		 3vt7A-6etzA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fob VITAMIN D3 RECEPTOR
A

(Danio rerio) 		no annotation 5 LEU A 261
VAL A 262
SER A 303
LEU A 338
HIS A 333
 DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.8A)
None
DZW  A 501 (-3.9A)
 1.31A 3vt7A-6fobA:
36.5		 3vt7A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fob VITAMIN D3 RECEPTOR
A

(Danio rerio) 		no annotation 7 TYR A 175
LEU A 261
VAL A 262
SER A 265
ARG A 302
SER A 303
LEU A 338
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.8A)
None
 1.18A 3vt7A-6fobA:
36.5		 3vt7A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fob VITAMIN D3 RECEPTOR
A

(Danio rerio) 		no annotation 11 TYR A 175
LEU A 261
VAL A 262
SER A 265
ARG A 302
SER A 303
SER A 306
VAL A 328
HIS A 333
LEU A 337
HIS A 423
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
None
DZW  A 501 (-4.0A)
 0.26A 3vt7A-6fobA:
36.5		 3vt7A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fob VITAMIN D3 RECEPTOR
A

(Danio rerio) 		no annotation 11 TYR A 175
TYR A 179
VAL A 262
SER A 265
ARG A 302
SER A 303
SER A 306
VAL A 328
HIS A 333
LEU A 337
HIS A 423
 None
DZW  A 501 ( 4.8A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
None
DZW  A 501 (-4.0A)
 0.62A 3vt7A-6fobA:
36.5		 3vt7A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ecx AMINOTRANSFERASE

(Thermotoga
maritima) 		PF00266
(Aminotran_5) 		4 LEU A 224
ILE A  92
TYR A 196
TYR A 108
 None
 0.90A 3vt7A-1ecxA:
0.0		 3vt7A-1ecxA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k0k PROFILIN

(Saccharomyces
cerevisiae) 		PF00235
(Profilin) 		4 LEU A  35
ILE A  77
TYR A 100
TYR A  21
 None
 1.44A 3vt7A-1k0kA:
undetectable		 3vt7A-1k0kA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r5p CIRCADIAN
OSCILLATION
REGULATOR

(Nostoc sp. PCC
7120) 		PF07689
(KaiB) 		4 LEU A  93
ILE A  77
TYR A  40
TYR A  13
 None
 1.40A 3vt7A-1r5pA:
undetectable		 3vt7A-1r5pA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tz7 4-ALPHA-GLUCANOTRANS
FERASE

(Aquifex
aeolicus) 		PF02446
(Glyco_hydro_77) 		4 LEU A 335
ILE A 389
TYR A 362
TYR A 380
 None
 1.27A 3vt7A-1tz7A:
0.0		 3vt7A-1tz7A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u71 DIHYDROFOLATE
REDUCTASE

(Homo sapiens) 		PF00186
(DHFR_1) 		4 LEU A 166
ILE A   7
TYR A 162
TYR A 177
 None
MXA  A 187 (-4.5A)
None
None
 1.36A 3vt7A-1u71A:
undetectable		 3vt7A-1u71A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uf3 HYPOTHETICAL PROTEIN
TT1561

(Thermus
thermophilus) 		PF14582
(Metallophos_3) 		4 LEU A  21
ILE A   8
TYR A 212
TYR A  68
 None
 1.14A 3vt7A-1uf3A:
undetectable		 3vt7A-1uf3A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrg PROPIONYL-COA
CARBOXYLASE, BETA
SUBUNIT

(Thermotoga
maritima) 		PF01039
(Carboxyl_trans) 		4 LEU A 334
ILE A 398
TYR A 403
TYR A 387
 None
 1.22A 3vt7A-1vrgA:
0.0		 3vt7A-1vrgA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wch PROTEIN TYROSINE
PHOSPHATASE,
NON-RECEPTOR TYPE 13

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 LEU A2208
ILE A2421
TYR A2466
TYR A2457
 None
 1.48A 3vt7A-1wchA:
undetectable		 3vt7A-1wchA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wwy THIOREDOXIN-LIKE
PROTEIN 1

(Homo sapiens) 		PF06201
(PITH) 		4 LEU A  12
ILE A 116
TYR A 148
TYR A  64
 None
 1.27A 3vt7A-1wwyA:
undetectable		 3vt7A-1wwyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xww LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE

(Homo sapiens) 		PF01451
(LMWPc) 		4 LEU A  29
ILE A 127
TYR A 119
TYR A 142
 GOL  A 202 (-3.8A)
None
None
None
 1.43A 3vt7A-1xwwA:
undetectable		 3vt7A-1xwwA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z26 ARGONAUTE

(Pyrococcus
furiosus) 		PF02171
(Piwi)
PF12212
(PAZ_siRNAbind) 		4 LEU A 177
ILE A 182
TYR A 190
TYR A 122
 None
 1.34A 3vt7A-1z26A:
undetectable		 3vt7A-1z26A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2axo HYPOTHETICAL PROTEIN
ATU2684

(Agrobacterium
fabrum) 		PF06764
(DUF1223) 		4 LEU A 120
ILE A  68
TYR A  78
TYR A 135
 None
 1.45A 3vt7A-2axoA:
undetectable		 3vt7A-2axoA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bhm TYPE IV SECRETION
SYSTEM PROTEIN VIRB8

(Brucella suis) 		PF04335
(VirB8) 		4 LEU A 132
ILE A 165
TYR A 229
TYR A 105
 None
 1.09A 3vt7A-2bhmA:
0.4		 3vt7A-2bhmA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ct8 METHIONYL-TRNA
SYNTHETASE

(Aquifex
aeolicus) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g) 		4 LEU A 255
ILE A 402
TYR A  37
TYR A  26
 None
 1.39A 3vt7A-2ct8A:
undetectable		 3vt7A-2ct8A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e1m L-GLUTAMATE OXIDASE

(Streptomyces
sp. X-119-6) 		PF01593
(Amino_oxidase) 		4 LEU A 133
ILE A 320
TYR A 167
TYR A 326
 None
 1.42A 3vt7A-2e1mA:
undetectable		 3vt7A-2e1mA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eae ALPHA-FUCOSIDASE

(Bifidobacterium
bifidum) 		PF14498
(Glyco_hyd_65N_2) 		4 LEU A  51
ILE A 765
TYR A 753
TYR A 380
 None
 1.43A 3vt7A-2eaeA:
undetectable		 3vt7A-2eaeA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6i ATP-DEPENDENT CLP
PROTEASE, PUTATIVE

(Plasmodium
falciparum) 		PF00574
(CLP_protease) 		4 LEU A 189
ILE A 226
TYR A 198
TYR A 217
 None
 1.09A 3vt7A-2f6iA:
undetectable		 3vt7A-2f6iA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE

(Sulfurisphaera
tokodaii) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 LEU A 352
ILE A 281
TYR A 333
TYR A 294
 None
 1.36A 3vt7A-2f7lA:
undetectable		 3vt7A-2f7lA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fk7 METHOXY MYCOLIC ACID
SYNTHASE 4

(Mycobacterium
tuberculosis) 		PF02353
(CMAS) 		4 LEU A  54
ILE A 145
TYR A  59
TYR A 241
 None
 1.29A 3vt7A-2fk7A:
undetectable		 3vt7A-2fk7A:
22.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2o4j VITAMIN D3 RECEPTOR

(Rattus
norvegicus) 		PF00104
(Hormone_recep) 		4 LEU A 223
ILE A 267
TYR A 291
TYR A 397
 None
VD4  A 500 ( 4.7A)
None
None
 0.12A 3vt7A-2o4jA:
39.4		 3vt7A-2o4jA:
99.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4u ACID PHOSPHATASE 1

(Mus musculus) 		PF01451
(LMWPc) 		4 LEU A  30
ILE A 128
TYR A 120
TYR A 143
 None
 1.34A 3vt7A-2p4uA:
undetectable		 3vt7A-2p4uA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbe AMINOGLYCOSIDE
6-ADENYLYLTRANSFERAS
E

(Bacillus
subtilis) 		PF04439
(Adenyl_transf) 		4 LEU A 182
ILE A 279
TYR A 236
TYR A 247
 None
 1.47A 3vt7A-2pbeA:
undetectable		 3vt7A-2pbeA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qve TYROSINE AMINOMUTASE

(Streptomyces
globisporus) 		PF00221
(Lyase_aromatic) 		4 LEU A 276
ILE A 479
TYR A 494
TYR A 393
 None
 1.40A 3vt7A-2qveA:
1.4		 3vt7A-2qveA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB

(Streptococcus
pneumoniae) 		no annotation 4 LEU A  91
ILE A 134
TYR A 104
TYR A  83
 None
 1.50A 3vt7A-2wjfA:
undetectable		 3vt7A-2wjfA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wwd 1,4-BETA-N-ACETYLMUR
AMIDASE

(Streptococcus
pneumoniae) 		PF01183
(Glyco_hydro_25)
PF01473
(CW_binding_1) 		4 LEU A 300
ILE A 271
TYR A 405
TYR A 324
 None
None
NAG  A 469 (-4.8A)
None
 1.33A 3vt7A-2wwdA:
undetectable		 3vt7A-2wwdA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ylf PROTEIN SPIRE
HOMOLOG 1

(Homo sapiens) 		PF16474
(KIND) 		4 LEU A 156
ILE A  53
TYR A 134
TYR A 217
 None
 1.43A 3vt7A-2ylfA:
undetectable		 3vt7A-2ylfA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hbz PUTATIVE GLYCOSIDE
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF13201
(PCMD) 		4 LEU A 320
ILE A 203
TYR A 265
TYR A 357
 None
 1.27A 3vt7A-3hbzA:
undetectable		 3vt7A-3hbzA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwg ACETYLTRANSFERASE,
GNAT FAMILY

(Colwellia
psychrerythraea) 		PF00583
(Acetyltransf_1) 		4 LEU A  16
ILE A  83
TYR A 106
TYR A  46
 None
 1.45A 3vt7A-3iwgA:
undetectable		 3vt7A-3iwgA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6r PROPIONYL-COA
CARBOXYLASE, BETA
SUBUNIT

(Roseobacter
denitrificans) 		PF01039
(Carboxyl_trans) 		4 LEU B 366
ILE B 430
TYR B 435
TYR B 419
 None
 1.46A 3vt7A-3n6rB:
undetectable		 3vt7A-3n6rB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nj2 DUF269-CONTAINING
PROTEIN

(Cyanothece sp.
ATCC 51142) 		PF03270
(DUF269) 		4 LEU A  87
ILE A  62
TYR A  92
TYR A  53
 None
 1.50A 3vt7A-3nj2A:
undetectable		 3vt7A-3nj2A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3on7 OXIDOREDUCTASE,
IRON/ASCORBATE
FAMILY

(Shewanella
oneidensis) 		PF03171
(2OG-FeII_Oxy)
PF14226
(DIOX_N) 		4 LEU A 150
ILE A 245
TYR A 108
TYR A  88
 None
 1.14A 3vt7A-3on7A:
undetectable		 3vt7A-3on7A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3prc PHOTOSYNTHETIC
REACTION CENTER

(Blastochloris
viridis) 		PF00124
(Photo_RC) 		4 LEU L   3
ILE L 107
TYR L  29
TYR L   9
 None
 1.39A 3vt7A-3prcL:
undetectable		 3vt7A-3prcL:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r7g PROTEIN SPIRE
HOMOLOG 1

(Homo sapiens) 		PF16474
(KIND) 		4 LEU A 156
ILE A  53
TYR A 134
TYR A 217
 None
 1.49A 3vt7A-3r7gA:
undetectable		 3vt7A-3r7gA:
21.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3wgp VITAMIN D3 RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 LEU A 227
ILE A 271
TYR A 295
TYR A 401
 None
ED9  A 501 (-4.5A)
None
None
 0.39A 3vt7A-3wgpA:
36.6		 3vt7A-3wgpA:
90.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3win HA3

(Clostridium
botulinum) 		PF03505
(Clenterotox) 		4 LEU E 587
ILE E 624
TYR E 604
TYR E 558
 None
 1.16A 3vt7A-3winE:
undetectable		 3vt7A-3winE:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)

(Bacteroides
ovatus) 		PF00150
(Cellulase)
PF13004
(BACON) 		4 LEU A 480
ILE A 380
TYR A 476
TYR A 431
 None
GLC  A1519 ( 3.9A)
XYS  A1524 (-3.9A)
None
 1.35A 3vt7A-3zmrA:
undetectable		 3vt7A-3zmrA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1

(Rattus
norvegicus) 		PF01150
(GDA1_CD39) 		4 LEU A  53
ILE A 116
TYR A  65
TYR A 159
 None
 1.32A 3vt7A-3zx2A:
undetectable		 3vt7A-3zx2A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aco CENTROMERE
DNA-BINDING PROTEIN
COMPLEX CBF3 SUBUNIT
A

(Saccharomyces
cerevisiae) 		PF16787
(NDC10_II) 		4 LEU A 432
ILE A 484
TYR A 295
TYR A 498
 None
 1.36A 3vt7A-4acoA:
undetectable		 3vt7A-4acoA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akz TYPE IV SECRETION
SYSTEM PROTEIN VIRB8

(Brucella suis) 		PF04335
(VirB8) 		4 LEU A 132
ILE A 165
TYR A 229
TYR A 105
 None
 1.10A 3vt7A-4akzA:
undetectable		 3vt7A-4akzA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g5a UNCHARACTERIZED
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF11589
(DUF3244) 		4 LEU A  45
ILE A  83
TYR A 107
TYR A  92
 None
 1.07A 3vt7A-4g5aA:
undetectable		 3vt7A-4g5aA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hhx TOXIN COREGULATED
PILUS BIOSYNTHESIS
PROTEIN E

(Vibrio cholerae) 		PF00482
(T2SSF) 		4 LEU A  66
ILE A  33
TYR A  27
TYR A  13
 None
 1.20A 3vt7A-4hhxA:
undetectable		 3vt7A-4hhxA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iiw LMO1499 PROTEIN

(Listeria
monocytogenes) 		PF02618
(YceG) 		4 LEU A 230
ILE A 129
TYR A 271
TYR A 184
 None
 1.45A 3vt7A-4iiwA:
undetectable		 3vt7A-4iiwA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jc8 HOPS COMPONENT VPS33

(Chaetomium
thermophilum) 		PF00995
(Sec1) 		4 LEU A 255
ILE A 617
TYR A 309
TYR A 518
 None
 1.18A 3vt7A-4jc8A:
undetectable		 3vt7A-4jc8A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kso CIRCADIAN CLOCK
PROTEIN KAIB

(Synechococcus
elongatus) 		no annotation 4 LEU C  92
ILE C  76
TYR C  39
TYR C  12
 None
 1.17A 3vt7A-4ksoC:
undetectable		 3vt7A-4ksoC:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kz1 VIRB8 PROTEIN

(Bartonella
grahamii) 		PF04335
(VirB8) 		4 LEU A  66
ILE A 107
TYR A 165
TYR A  43
 None
 1.12A 3vt7A-4kz1A:
undetectable		 3vt7A-4kz1A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lh7 DNA LIGASE

(Enterococcus
faecalis) 		PF01653
(DNA_ligase_aden) 		4 LEU A  89
ILE A 285
TYR A 314
TYR A 227
 1X8  A 401 (-4.0A)
None
None
1X8  A 401 (-3.6A)
 1.41A 3vt7A-4lh7A:
1.3		 3vt7A-4lh7A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lso TYPE IV SECRETION
SYSTEM PROTEIN VIRB8

(Bartonella
quintana) 		PF04335
(VirB8) 		4 LEU A 131
ILE A 165
TYR A 226
TYR A 104
 None
 1.11A 3vt7A-4lsoA:
undetectable		 3vt7A-4lsoA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nw4 LIPOPROTEIN S-LAYER
PROTEIN

(Enterococcus
faecalis) 		PF16103
(DUF4822) 		4 LEU A 138
ILE A 126
TYR A 254
TYR A  90
 GOL  A 409 (-4.8A)
None
None
None
 1.30A 3vt7A-4nw4A:
undetectable		 3vt7A-4nw4A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7b CHOLINE KINASE

(Streptococcus
pneumoniae) 		PF01633
(Choline_kinase) 		4 LEU A 280
ILE A 250
TYR A 243
TYR A 273
 None
 1.36A 3vt7A-4r7bA:
undetectable		 3vt7A-4r7bA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ufc GH95

(Bacteroides
ovatus) 		PF14498
(Glyco_hyd_65N_2) 		4 LEU A  37
ILE A 669
TYR A 657
TYR A 338
 None
 1.43A 3vt7A-4ufcA:
undetectable		 3vt7A-4ufcA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd3 L-AMINO ACID LIGASE

(Bacillus
subtilis) 		PF13535
(ATP-grasp_4) 		4 LEU A  66
ILE A  77
TYR A  50
TYR A  94
 None
 1.36A 3vt7A-4wd3A:
undetectable		 3vt7A-4wd3A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmm NUCLEOPORIN NUP145

(Saccharomyces
cerevisiae) 		PF12110
(Nup96) 		4 LEU B 326
ILE B 292
TYR B 298
TYR B 359
 None
 1.40A 3vt7A-4xmmB:
undetectable		 3vt7A-4xmmB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y4r BIFUNCTIONAL
LYSINE-SPECIFIC
DEMETHYLASE AND
HISTIDYL-HYDROXYLASE
NO66

(Homo sapiens) 		PF08007
(Cupin_4) 		4 LEU A 299
ILE A 344
TYR A 565
TYR A 328
 None
None
None
ACT  A 702 (-3.4A)
 1.46A 3vt7A-4y4rA:
undetectable		 3vt7A-4y4rA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y4v CONSERVED
HYPOTHETICAL
SECRETED PROTEIN

(Helicobacter
pylori) 		PF03734
(YkuD) 		4 LEU A  80
ILE A 278
TYR A 120
TYR A  83
 None
 1.43A 3vt7A-4y4vA:
undetectable		 3vt7A-4y4vA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z45 ODORANT-BINDING
PROTEIN NRIBOBP3

(Nasonovia
ribisnigri) 		PF01395
(PBP_GOBP) 		4 LEU A  51
ILE A  10
TYR A 105
TYR A  70
 None
 1.12A 3vt7A-4z45A:
undetectable		 3vt7A-4z45A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5en6 SMU-1

(Caenorhabditis
elegans) 		no annotation 4 LEU A  85
ILE A 145
TYR A 133
TYR A  78
 None
 1.39A 3vt7A-5en6A:
undetectable		 3vt7A-5en6A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fpr DNA LIGASE

(Staphylococcus
aureus) 		PF01653
(DNA_ligase_aden) 		4 LEU A  82
ILE A 277
TYR A 306
TYR A 219
 None
 1.31A 3vt7A-5fprA:
1.3		 3vt7A-5fprA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fqe BETA-N-ACETYLGALACTO
SAMINIDASE

(Clostridium
perfringens) 		PF13320
(DUF4091) 		4 LEU A 206
ILE A 222
TYR A 213
TYR A 184
 None
 1.38A 3vt7A-5fqeA:
undetectable		 3vt7A-5fqeA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inf CARBOXYL TRANSFERASE

(Streptomyces
ambofaciens) 		PF01039
(Carboxyl_trans) 		4 LEU A 349
ILE A 413
TYR A 418
TYR A 402
 None
 1.32A 3vt7A-5infA:
undetectable		 3vt7A-5infA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jo7 VETISPIRADIENE
SYNTHASE 1

(Hyoscyamus
muticus) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 LEU A 297
ILE A 379
TYR A 353
TYR A 411
 None
 1.23A 3vt7A-5jo7A:
undetectable		 3vt7A-5jo7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbf CAMP-DEPENDENT
PROTEIN KINASE
REGULATORY SUBUNIT,
PUTATIVE

(Plasmodium
falciparum) 		PF00027
(cNMP_binding) 		4 LEU A 263
ILE A 217
TYR A 222
TYR A 319
 None
CMP  A 501 ( 4.9A)
None
CMP  A 501 (-3.6A)
 1.37A 3vt7A-5kbfA:
undetectable		 3vt7A-5kbfA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nnp N-TERMINAL
ACETYLTRANSFERASE-LI
KE PROTEIN

(Chaetomium
thermophilum) 		PF12569
(NARP1)
PF13432
(TPR_16) 		4 LEU A 138
ILE A 536
TYR A 130
TYR A 171
 None
 1.00A 3vt7A-5nnpA:
undetectable		 3vt7A-5nnpA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oa3 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 2D

(Homo sapiens) 		no annotation 4 LEU 0 476
ILE 0 491
TYR 0 564
TYR 0 472
 None
 1.42A 3vt7A-5oa30:
undetectable		 3vt7A-5oa30:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uv2 (+)-LIMONENE
SYNTHASE

(Citrus sinensis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 LEU A 196
ILE A 483
TYR A 193
TYR A 538
 None
 1.04A 3vt7A-5uv2A:
undetectable		 3vt7A-5uv2A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wru PROBABLE INORGANIC
PYROPHOSPHATASE

(Plasmodium
falciparum) 		no annotation 4 LEU A 212
ILE A 148
TYR A 168
TYR A  66
 None
 1.40A 3vt7A-5wruA:
undetectable		 3vt7A-5wruA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ydj ACETYLCHOLINESTERASE

(Anopheles
gambiae) 		no annotation 4 LEU A 690
ILE A 446
TYR A 522
TYR A 535
 None
 1.44A 3vt7A-5ydjA:
undetectable		 3vt7A-5ydjA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c1d UNCONVENTIONAL
MYOSIN-IB

(Rattus
norvegicus) 		no annotation 4 LEU P 189
ILE P 414
TYR P 169
TYR P 406
 None
 1.41A 3vt7A-6c1dP:
undetectable		 3vt7A-6c1dP:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1

(Homo sapiens) 		no annotation 4 LEU B 143
ILE B 223
TYR B 344
TYR B 191
 None
 1.49A 3vt7A-6d6uB:
undetectable		 3vt7A-6d6uB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eua ANGIOPOIETIN-RELATED
PROTEIN 3

(Homo sapiens) 		no annotation 4 LEU A 450
ILE A 262
TYR A 329
TYR A 273
 None
 1.26A 3vt7A-6euaA:
undetectable		 3vt7A-6euaA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fj4 ENDO-1,4-BETA-XYLANA
SE Y

(Ruminiclostridium
thermocellum) 		no annotation 4 LEU A 893
ILE A 859
TYR A 973
TYR A 846
 None
 1.33A 3vt7A-6fj4A:
undetectable		 3vt7A-6fj4A:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fob VITAMIN D3 RECEPTOR
A

(Danio rerio) 		no annotation 4 LEU A 255
ILE A 299
TYR A 323
TYR A 427
 None
DZW  A 501 (-4.7A)
DZW  A 501 (-3.6A)
DZW  A 501 (-4.9A)
 0.42A 3vt7A-6fobA:
36.5		 3vt7A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gsa -

(-) 		no annotation 4 LEU E 432
ILE E 484
TYR E 295
TYR E 498
 None
 1.36A 3vt7A-6gsaE:
undetectable		 3vt7A-6gsaE:
undetectable