SIMILAR PATTERNS OF AMINO ACIDS FOR 3VKX_A_T3A301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE


(Cellvibrio
japonicus)
PF02156
(Glyco_hydro_26)
4 MET A 308
LEU A 280
PRO A 272
PRO A 256
None
1.30A 3vkxA-1gw1A:
undetectable
3vkxA-1gw1A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hn0 CHONDROITIN ABC
LYASE I


(Proteus
vulgaris)
PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt)
4 MET A 735
LEU A 642
GLN A 671
PRO A 556
None
1.33A 3vkxA-1hn0A:
0.1
3vkxA-1hn0A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2o TRANSALDOLASE B

(Escherichia
coli)
PF00923
(TAL_FSA)
4 LEU A  26
PRO A 246
PRO A  29
TYR A  27
None
1.43A 3vkxA-1i2oA:
undetectable
3vkxA-1i2oA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqp DIPEPTIDYL PEPTIDASE
I


(Rattus
norvegicus)
PF00112
(Peptidase_C1)
PF08773
(CathepsinC_exc)
4 LEU A 242
PRO A 436
GLN A 254
PRO A 256
None
1.43A 3vkxA-1jqpA:
0.1
3vkxA-1jqpA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lgf P450 MONOOXYGENASE

(Amycolatopsis
orientalis)
PF00067
(p450)
4 MET A 244
LEU A 280
PRO A  18
TYR A 279
None
0.95A 3vkxA-1lgfA:
undetectable
3vkxA-1lgfA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE


(Homo sapiens)
PF02898
(NO_synthase)
4 LEU A 273
PRO A 479
GLN A 294
PRO A 300
None
1.23A 3vkxA-1m9qA:
undetectable
3vkxA-1m9qA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q7r PREDICTED
AMIDOTRANSFERASE


(Geobacillus
stearothermophilus)
PF01174
(SNO)
4 MET A  51
LEU A  54
GLN A  34
TYR A  58
None
1.18A 3vkxA-1q7rA:
0.0
3vkxA-1q7rA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r2f PROTEIN
(RIBONUCLEOTIDE
REDUCTASE R2)


(Salmonella
enterica)
PF00268
(Ribonuc_red_sm)
4 LEU A 240
GLN A 132
PRO A 130
TYR A 236
None
1.34A 3vkxA-1r2fA:
undetectable
3vkxA-1r2fA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txd RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 12


(Homo sapiens)
PF00621
(RhoGEF)
4 MET A 934
LEU A 937
PRO A 941
TYR A 940
None
1.21A 3vkxA-1txdA:
0.0
3vkxA-1txdA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ued P450 MONOOXYGENASE

(Amycolatopsis
orientalis)
PF00067
(p450)
4 MET A 253
LEU A 289
PRO A  26
TYR A 288
HEM  A1430 (-4.6A)
None
None
None
1.02A 3vkxA-1uedA:
undetectable
3vkxA-1uedA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1n 4-ALPHA-GLUCANOTRANS
FERASE


(Solanum
tuberosum)
PF02446
(Glyco_hydro_77)
4 MET A 110
PRO A  48
GLN A  49
PRO A  40
None
1.04A 3vkxA-1x1nA:
undetectable
3vkxA-1x1nA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8q UBIQUITIN-LIKE 2
ACTIVATING ENZYME
E1B


(Homo sapiens)
PF00899
(ThiF)
PF14732
(UAE_UbL)
PF16195
(UBA2_C)
4 MET B 269
LEU B 272
PRO B 179
PRO B 279
None
1.13A 3vkxA-1y8qB:
undetectable
3vkxA-1y8qB:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2abj BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE,
CYTOSOLIC


(Homo sapiens)
PF01063
(Aminotran_4)
4 MET A 326
LEU A 263
GLN A 252
PRO A 277
None
1.46A 3vkxA-2abjA:
undetectable
3vkxA-2abjA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ciu IMPORT INNER
MEMBRANE TRANSLOCASE
SUBUNIT TIM21
MITOCHONDRIAL


(Saccharomyces
cerevisiae)
PF08294
(TIM21)
4 MET A 172
LEU A 187
GLN A 197
PRO A 198
None
1.40A 3vkxA-2ciuA:
undetectable
3vkxA-2ciuA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fge ZINC METALLOPROTEASE
(INSULINASE FAMILY)


(Arabidopsis
thaliana)
PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc)
4 LEU A 727
PRO A 592
GLN A 717
TYR A 723
None
1.24A 3vkxA-2fgeA:
undetectable
3vkxA-2fgeA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gwc GLUTAMATE CYSTEINE
LIGASE


(Brassica juncea)
PF04107
(GCS2)
4 MET A 384
LEU A 380
GLN A 319
TYR A 320
None
1.48A 3vkxA-2gwcA:
undetectable
3vkxA-2gwcA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h5r MSTRAWBERRY

(Discosoma sp.)
PF01353
(GFP)
4 LEU A  83
GLN A 188
PRO A 190
TYR A  82
None
1.35A 3vkxA-2h5rA:
undetectable
3vkxA-2h5rA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hky RIBONUCLEASE 7

(Homo sapiens)
PF00074
(RnaseA)
4 MET A  80
LEU A  78
GLN A  71
TYR A 102
None
1.26A 3vkxA-2hkyA:
undetectable
3vkxA-2hkyA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE


(Enterovirus C)
PF00548
(Peptidase_C3)
PF00680
(RdRP_1)
4 MET 1 324
LEU 1 327
PRO 1 302
TYR 1 331
None
1.44A 3vkxA-2ijd1:
undetectable
3vkxA-2ijd1:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ime 2-HYDROXYCHROMENE-2-
CARBOXYLATE
ISOMERASE


(Pseudomonas
putida)
PF01323
(DSBA)
4 LEU A  10
PRO A  12
PRO A  81
TYR A  84
2C2  A 305 ( 4.2A)
GSH  A 301 ( 4.5A)
None
TOH  A 304 (-4.0A)
1.47A 3vkxA-2imeA:
undetectable
3vkxA-2imeA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ox4 PUTATIVE MANDELATE
RACEMASE


(Zymomonas
mobilis)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 LEU A 353
PRO A  15
GLN A  16
TYR A 350
None
1.21A 3vkxA-2ox4A:
undetectable
3vkxA-2ox4A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pt6 SPERMIDINE SYNTHASE

(Plasmodium
falciparum)
PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N)
4 LEU A 134
PRO A 110
PRO A 117
TYR A 137
None
1.42A 3vkxA-2pt6A:
undetectable
3vkxA-2pt6A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9h H(+)/CL(-) EXCHANGE
TRANSPORTER CLCA


(Escherichia
coli)
PF00654
(Voltage_CLC)
4 MET A 143
LEU A 145
GLN A 153
PRO A 150
None
1.45A 3vkxA-2r9hA:
undetectable
3vkxA-2r9hA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vxo GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]


(Homo sapiens)
PF00117
(GATase)
PF00958
(GMP_synt_C)
PF02540
(NAD_synthase)
4 LEU A 443
PRO A 612
GLN A 610
PRO A 439
None
None
XMP  A1694 (-3.0A)
XMP  A1694 (-4.1A)
0.83A 3vkxA-2vxoA:
undetectable
3vkxA-2vxoA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfb E1 ENVELOPE
GLYCOPROTEIN


(Chikungunya
virus)
PF01589
(Alpha_E1_glycop)
4 PRO A  58
GLN A 102
PRO A  86
TYR A  93
None
1.19A 3vkxA-2xfbA:
undetectable
3vkxA-2xfbA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzl ATP-DEPENDENT
HELICASE NAM7


(Saccharomyces
cerevisiae)
PF09416
(UPF1_Zn_bind)
PF13086
(AAA_11)
PF13087
(AAA_12)
4 MET A 361
PRO A 460
GLN A 576
PRO A 604
None
1.36A 3vkxA-2xzlA:
undetectable
3vkxA-2xzlA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yy5 TRYPTOPHANYL-TRNA
SYNTHETASE


(Mycoplasma
pneumoniae)
PF00579
(tRNA-synt_1b)
4 MET A  90
LEU A 143
PRO A 146
TYR A 144
None
1.44A 3vkxA-2yy5A:
undetectable
3vkxA-2yy5A:
22.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2


(Arabidopsis
thaliana)
PF00705
(PCNA_N)
PF02747
(PCNA_C)
4 MET A  40
LEU A  47
PRO A 234
TYR A 250
None
0.51A 3vkxA-2zvwA:
36.4
3vkxA-2zvwA:
61.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdu PUTATIVE LIPOPROTEIN

(Pectobacterium
atrosepticum)
PF06004
(DUF903)
4 MET A  50
LEU A   7
GLN A  41
TYR A  32
None
1.34A 3vkxA-3bduA:
undetectable
3vkxA-3bduA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ciy TOLL-LIKE RECEPTOR 3

(Mus musculus)
PF00560
(LRR_1)
PF13855
(LRR_8)
4 MET A 642
LEU A 640
GLN A 635
PRO A 633
None
1.37A 3vkxA-3ciyA:
undetectable
3vkxA-3ciyA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eoe PYRUVATE KINASE

(Toxoplasma
gondii)
PF00224
(PK)
PF02887
(PK_C)
4 MET A 193
PRO A 149
GLN A 150
TYR A 145
None
1.48A 3vkxA-3eoeA:
undetectable
3vkxA-3eoeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqn GLUCAN
1,3-BETA-GLUCOSIDASE


(Phanerochaete
chrysosporium)
PF12708
(Pectate_lyase_3)
4 MET A 595
LEU A 554
GLN A 470
PRO A 469
None
1.38A 3vkxA-3eqnA:
undetectable
3vkxA-3eqnA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqn GLUCAN
1,3-BETA-GLUCOSIDASE


(Phanerochaete
chrysosporium)
PF12708
(Pectate_lyase_3)
4 MET A 595
LEU A 554
PRO A 471
GLN A 470
None
1.41A 3vkxA-3eqnA:
undetectable
3vkxA-3eqnA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ian CHITINASE

(Lactococcus
lactis)
PF00704
(Glyco_hydro_18)
4 LEU A 260
PRO A 202
GLN A 231
TYR A 228
None
1.48A 3vkxA-3ianA:
undetectable
3vkxA-3ianA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kz1 RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 11


(Homo sapiens)
PF00621
(RhoGEF)
4 MET A 879
LEU A 882
PRO A 886
TYR A 885
None
1.21A 3vkxA-3kz1A:
undetectable
3vkxA-3kz1A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l6i UNCHARACTERIZED
LIPOPROTEIN YCEB


(Escherichia
coli)
PF07273
(DUF1439)
4 MET A 124
LEU A 127
PRO A  41
TYR A 130
None
0.96A 3vkxA-3l6iA:
undetectable
3vkxA-3l6iA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzo LIN2634 PROTEIN

(Listeria
innocua)
PF12917
(HD_2)
4 LEU A 119
PRO A 114
GLN A 113
TYR A 116
None
1.46A 3vkxA-3mzoA:
undetectable
3vkxA-3mzoA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA


(Escherichia
coli)
no annotation 4 LEU B 240
GLN B 132
PRO B 130
TYR B 236
None
1.37A 3vkxA-3n3bB:
undetectable
3vkxA-3n3bB:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ncf PROLACTIN RECEPTOR

(Homo sapiens)
PF09067
(EpoR_lig-bind)
4 LEU B 172
PRO B 121
GLN B 115
PRO B 203
None
1.44A 3vkxA-3ncfB:
undetectable
3vkxA-3ncfB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nhi D7 PROTEIN

(Anopheles
stephensi)
PF01395
(PBP_GOBP)
4 LEU A 127
PRO A  76
GLN A  97
TYR A  96
None
1.05A 3vkxA-3nhiA:
undetectable
3vkxA-3nhiA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1


(Homo sapiens)
PF00621
(RhoGEF)
4 MET A 562
LEU A 565
PRO A 569
TYR A 568
None
1.26A 3vkxA-3odoA:
undetectable
3vkxA-3odoA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odw RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1


(Homo sapiens)
PF00621
(RhoGEF)
4 MET A 562
LEU A 565
PRO A 569
TYR A 568
None
1.18A 3vkxA-3odwA:
undetectable
3vkxA-3odwA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odx RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1


(Homo sapiens)
PF00621
(RhoGEF)
4 MET A 562
LEU A 565
PRO A 569
TYR A 568
None
1.17A 3vkxA-3odxA:
undetectable
3vkxA-3odxA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pdf DIPEPTIDYL PEPTIDASE
1


(Homo sapiens)
PF00112
(Peptidase_C1)
PF08773
(CathepsinC_exc)
4 LEU A 243
PRO A 437
GLN A 255
PRO A 257
None
1.40A 3vkxA-3pdfA:
undetectable
3vkxA-3pdfA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poc ALPHA-GLUCOSIDASE

(Blautia obeum)
PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
4 LEU A 429
GLN A 545
PRO A 556
TYR A 558
None
1.26A 3vkxA-3pocA:
undetectable
3vkxA-3pocA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rys ADENOSINE DEAMINASE
1


(Paenarthrobacter
aurescens)
PF00962
(A_deaminase)
4 LEU A  65
PRO A  28
GLN A  27
TYR A 284
None
1.32A 3vkxA-3rysA:
undetectable
3vkxA-3rysA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vss BETA-FRUCTOFURANOSID
ASE


(Microbacterium
saccharophilum)
PF02435
(Glyco_hydro_68)
4 LEU A 364
PRO A 420
GLN A 419
TYR A 418
None
1.39A 3vkxA-3vssA:
undetectable
3vkxA-3vssA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wg1 GALACTOSIDE-BINDING
LECTIN


(Agrocybe
aegerita)
PF00337
(Gal-bind_lectin)
4 LEU A  53
PRO A  79
GLN A  78
TYR A  59
None
1.37A 3vkxA-3wg1A:
undetectable
3vkxA-3wg1A:
22.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4cs5 PROLIFERATING CELL
NUCLEAR ANTIGEN


(Litopenaeus
vannamei)
PF00705
(PCNA_N)
PF02747
(PCNA_C)
4 MET A  40
LEU A  47
PRO A 129
PRO A 234
None
0.68A 3vkxA-4cs5A:
36.9
3vkxA-4cs5A:
73.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eh1 FLAVOHEMOPROTEIN

(Vibrio cholerae)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6)
4 LEU A 137
GLN A  36
PRO A  37
TYR A 111
None
1.37A 3vkxA-4eh1A:
undetectable
3vkxA-4eh1A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f7z RAP GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 4


(Mus musculus)
PF00027
(cNMP_binding)
PF00610
(DEP)
PF00617
(RasGEF)
PF00618
(RasGEF_N)
4 MET A 933
PRO A 524
GLN A 527
PRO A 487
None
1.23A 3vkxA-4f7zA:
undetectable
3vkxA-4f7zA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fln PROTEASE DO-LIKE 2,
CHLOROPLASTIC


(Arabidopsis
thaliana)
PF13180
(PDZ_2)
PF13365
(Trypsin_2)
4 LEU A 455
PRO A 450
GLN A 483
PRO A 430
None
1.14A 3vkxA-4flnA:
undetectable
3vkxA-4flnA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fnm E3 ALPHA-ESTERASE-7
CARBOXYLESTERASE


(Lucilia cuprina)
PF00135
(COesterase)
4 MET A 547
LEU A 539
GLN A 506
PRO A 513
None
1.12A 3vkxA-4fnmA:
undetectable
3vkxA-4fnmA:
18.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hk1 PROLIFERATING CELL
NUCLEAR ANTIGEN


(Drosophila
melanogaster)
PF00705
(PCNA_N)
PF02747
(PCNA_C)
4 MET A  40
LEU A  47
PRO A 234
TYR A 250
None
0.46A 3vkxA-4hk1A:
35.0
3vkxA-4hk1A:
70.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jz5 GP26

(Listeria phage
P40)
PF01183
(Glyco_hydro_25)
4 MET A  53
LEU A  48
GLN A  11
TYR A  16
None
1.47A 3vkxA-4jz5A:
undetectable
3vkxA-4jz5A:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lu0 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE


(Pseudomonas
aeruginosa)
PF00793
(DAHP_synth_1)
4 LEU A 264
PRO A 246
GLN A  42
TYR A  47
None
1.27A 3vkxA-4lu0A:
undetectable
3vkxA-4lu0A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mh0 RAP GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 4


(Mus musculus)
PF00027
(cNMP_binding)
PF00617
(RasGEF)
PF00618
(RasGEF_N)
4 MET E 933
PRO E 524
GLN E 527
PRO E 487
None
1.13A 3vkxA-4mh0E:
undetectable
3vkxA-4mh0E:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mks ENOLASE 2

(Lactobacillus
gasseri)
PF00113
(Enolase_C)
PF03952
(Enolase_N)
4 MET A 407
LEU A 175
PRO A 169
TYR A 419
None
1.36A 3vkxA-4mksA:
undetectable
3vkxA-4mksA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nle ADENYLOSUCCINATE
LYASE


(Mycolicibacterium
smegmatis)
PF00206
(Lyase_1)
PF10397
(ADSL_C)
4 MET A 262
LEU A 267
GLN A 360
PRO A 356
None
1.37A 3vkxA-4nleA:
undetectable
3vkxA-4nleA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oqr CYP105AS1

(Amycolatopsis
orientalis)
PF00067
(p450)
4 MET A 248
LEU A 279
PRO A  26
TYR A 278
None
1.04A 3vkxA-4oqrA:
undetectable
3vkxA-4oqrA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oqs CYP105AS1

(Amycolatopsis
orientalis)
PF00067
(p450)
4 MET A 248
LEU A 279
PRO A  26
TYR A 278
HEM  A 501 ( 4.5A)
None
None
None
1.01A 3vkxA-4oqsA:
undetectable
3vkxA-4oqsA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pvi GH62 HYDROLASE

(Mycothermus
thermophilus)
PF03664
(Glyco_hydro_62)
4 LEU A 121
PRO A 118
GLN A 313
TYR A 123
None
1.36A 3vkxA-4pviA:
undetectable
3vkxA-4pviA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rvc ABC TRANSPORTER
ATP-BINDING PROTEIN


(Geobacillus
kaustophilus)
PF00005
(ABC_tran)
4 LEU A 151
PRO A 154
GLN A  77
TYR A 104
None
1.41A 3vkxA-4rvcA:
undetectable
3vkxA-4rvcA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tll RECEPTOR SUBUNIT
GLUN2B


(Xenopus laevis)
PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd)
4 MET B 381
LEU B 379
GLN B 148
TYR B 374
None
1.42A 3vkxA-4tllB:
undetectable
3vkxA-4tllB:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uoe SPERMIDINE SYNTHASE

(Plasmodium
falciparum)
PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N)
4 LEU A 134
PRO A 110
PRO A 117
TYR A 137
None
1.45A 3vkxA-4uoeA:
undetectable
3vkxA-4uoeA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN


(Bacillus
anthracis)
PF01522
(Polysacc_deac_1)
4 MET A 174
LEU A 177
PRO A 145
TYR A 182
None
None
None
ACT  A1363 ( 4.4A)
1.25A 3vkxA-4v33A:
undetectable
3vkxA-4v33A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5z CHITINASE 60

(Moritella
marina)
PF00704
(Glyco_hydro_18)
4 LEU A 195
PRO A 203
GLN A 163
TYR A 201
None
1.16A 3vkxA-4w5zA:
undetectable
3vkxA-4w5zA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x81 MYCINAMICIN III
3''-O-METHYLTRANSFER
ASE


(Micromonospora
griseorubida)
PF05711
(TylF)
4 MET A 197
LEU A 200
PRO A 205
TYR A 204
None
1.28A 3vkxA-4x81A:
undetectable
3vkxA-4x81A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x90 GROUP XV
PHOSPHOLIPASE A2


(Homo sapiens)
PF02450
(LCAT)
4 MET A 147
LEU A 144
PRO A  11
TYR A 140
None
1.42A 3vkxA-4x90A:
undetectable
3vkxA-4x90A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xlg STRUCTURE-SPECIFIC
ENDONUCLEASE SUBUNIT
SLX1
STRUCTURE-SPECIFIC
ENDONUCLEASE SUBUNIT
SLX4


([Candida]
glabrata)
PF01541
(GIY-YIG)
PF09494
(Slx4)
4 MET A 126
PRO B 683
GLN A   5
PRO A   8
None
1.29A 3vkxA-4xlgA:
undetectable
3vkxA-4xlgA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xox 3-OXOACYL-ACP
SYNTHASE


(Vibrio cholerae)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
4 MET A 235
LEU A  79
PRO A 147
GLN A  64
None
1.14A 3vkxA-4xoxA:
undetectable
3vkxA-4xoxA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xwh ALPHA-N-ACETYLGLUCOS
AMINIDASE


(Homo sapiens)
PF05089
(NAGLU)
PF12971
(NAGLU_N)
PF12972
(NAGLU_C)
4 MET A 233
LEU A 230
PRO A 243
GLN A 171
None
1.35A 3vkxA-4xwhA:
undetectable
3vkxA-4xwhA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ye5 PEPTIDOGLYCAN
SYNTHETASE
PENICILLIN-BINDING
PROTEIN 3


(Bifidobacterium
adolescentis)
PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
4 MET A 190
LEU A 194
GLN A  79
TYR A 184
None
1.33A 3vkxA-4ye5A:
undetectable
3vkxA-4ye5A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z3y BENZOYL-COA
REDUCTASE, PUTATIVE


(Geobacter
metallireducens)
PF01314
(AFOR_C)
PF02730
(AFOR_N)
4 LEU A 351
PRO A 357
GLN A 358
TYR A 174
None
1.35A 3vkxA-4z3yA:
undetectable
3vkxA-4z3yA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z3y BENZOYL-COA
REDUCTASE, PUTATIVE


(Geobacter
metallireducens)
PF01314
(AFOR_C)
PF02730
(AFOR_N)
4 LEU A 447
GLN A 594
PRO A 595
TYR A 446
None
1.36A 3vkxA-4z3yA:
undetectable
3vkxA-4z3yA:
17.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ztd PROLIFERATING CELL
NUCLEAR ANTIGEN


(Homo sapiens)
PF00705
(PCNA_N)
PF02747
(PCNA_C)
6 MET A  40
LEU A  47
PRO A 129
GLN A 131
PRO A 234
TYR A 250
None
0.86A 3vkxA-4ztdA:
36.5
3vkxA-4ztdA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a22 VESICULAR STOMATITIS
VIRUS L POLYMERASE


(Vesicular
stomatitis
virus)
PF00946
(Mononeg_RNA_pol)
PF14314
(Methyltrans_Mon)
PF14318
(Mononeg_mRNAcap)
4 MET A1109
LEU A1110
GLN A1277
TYR A1295
None
1.47A 3vkxA-5a22A:
undetectable
3vkxA-5a22A:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a5t EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT A


(Oryctolagus
cuniculus)
PF01399
(PCI)
4 MET A 306
LEU A 271
GLN A 226
TYR A 275
None
1.40A 3vkxA-5a5tA:
undetectable
3vkxA-5a5tA:
10.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5a6d DNA POLYMERASE
SLIDING CLAMP


(Thermococcus
gammatolerans)
PF00705
(PCNA_N)
PF02747
(PCNA_C)
4 MET A  41
LEU A  48
PRO A 126
PRO A 226
None
0.92A 3vkxA-5a6dA:
31.0
3vkxA-5a6dA:
30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b16 MICROPROCESSOR
COMPLEX SUBUNIT
DGCR8
RIBONUCLEASE
3,DROSHA,RIBONUCLEAS
E
3,DROSHA,RIBONUCLEAS
E 3


(Homo sapiens)
PF00035
(dsrm)
PF00636
(Ribonuclease_3)
PF14622
(Ribonucleas_3_3)
no annotation
4 MET B 739
LEU B 742
PRO A 989
PRO A1082
None
1.17A 3vkxA-5b16B:
undetectable
3vkxA-5b16B:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b6t GLYCOSYL HYDROLASE
FAMILY 62 PROTEIN


(Coprinopsis
cinerea)
PF03664
(Glyco_hydro_62)
4 LEU A 175
PRO A 172
GLN A 356
TYR A 177
None
1.42A 3vkxA-5b6tA:
undetectable
3vkxA-5b6tA:
21.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5b7o PROLIFERATING CELL
NUCLEAR ANTIGEN


(Leishmania
donovani)
PF00705
(PCNA_N)
PF02747
(PCNA_C)
4 MET A  40
LEU A  47
PRO A 267
TYR A 283
None
0.65A 3vkxA-5b7oA:
34.6
3vkxA-5b7oA:
40.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c1i TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI


(Thermus
thermophilus)
PF08704
(GCD14)
4 MET A  85
LEU A 246
PRO A 196
GLN A 200
None
1.18A 3vkxA-5c1iA:
undetectable
3vkxA-5c1iA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdh MAJOR ACID
PHOSPHATASE


(Legionella
pneumophila)
PF00328
(His_Phos_2)
4 LEU A 161
GLN A 244
PRO A 243
TYR A 165
None
1.34A 3vkxA-5cdhA:
undetectable
3vkxA-5cdhA:
23.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5cfk PROLIFERATING CELL
NUCLEAR
ANTIGEN,PROLIFERATIN
G CELL NUCLEAR
ANTIGEN


(Leishmania
donovani)
PF00705
(PCNA_N)
PF02747
(PCNA_C)
4 MET A  40
LEU A  47
PRO A 234
TYR A 250
None
0.57A 3vkxA-5cfkA:
34.0
3vkxA-5cfkA:
43.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eny POLYKETIDE SYNTHASE
PKSL


(Bacillus
subtilis)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc)
4 MET A 489
LEU A 444
PRO A 579
TYR A 455
None
1.30A 3vkxA-5enyA:
undetectable
3vkxA-5enyA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eul AYC08

(Vicugna pacos)
PF07686
(V-set)
4 LEU V   4
PRO V 105
GLN V  98
TYR V  97
None
1.35A 3vkxA-5eulV:
undetectable
3vkxA-5eulV:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f1z NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 MET A1011
LEU A1014
GLN A 946
TYR A1019
None
1.26A 3vkxA-5f1zA:
undetectable
3vkxA-5f1zA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggy IRON(III) ABC
TRANSPORTER,
PERIPLASMIC
IRON-COMPOUND-BINDIN
G PROTEIN


(Vibrio cholerae)
PF01497
(Peripla_BP_2)
4 LEU A  80
PRO A  93
GLN A  73
PRO A  74
None
1.48A 3vkxA-5ggyA:
undetectable
3vkxA-5ggyA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2v IMPORTIN SUBUNIT
BETA-3


(Saccharomyces
cerevisiae)
PF13513
(HEAT_EZ)
4 LEU A 359
GLN A 308
PRO A 367
TYR A 363
None
1.27A 3vkxA-5h2vA:
undetectable
3vkxA-5h2vA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB


(Mus musculus)
PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
4 MET A 748
GLN A 687
PRO A 778
TYR A 691
None
1.32A 3vkxA-5hjrA:
undetectable
3vkxA-5hjrA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE


(Porphyromonas
endodontalis)
PF10459
(Peptidase_S46)
4 MET A  28
LEU A 574
PRO A 275
TYR A 274
None
1.41A 3vkxA-5jxkA:
undetectable
3vkxA-5jxkA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbp GLYCOSYL HYDROLASE,
FAMILY 38


(Enterococcus
faecalis)
PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid)
4 MET A 227
LEU A 225
GLN A 268
TYR A 263
None
1.34A 3vkxA-5kbpA:
undetectable
3vkxA-5kbpA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kku POLYKETIDE SYNTHASE
TYPE I


(Bacillus
amyloliquefaciens)
PF14765
(PS-DH)
4 LEU A  50
PRO A  82
GLN A   7
TYR A  49
None
1.36A 3vkxA-5kkuA:
undetectable
3vkxA-5kkuA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldd RAB SMALL MONOMERIC
GTPASE-LIKE PROTEIN


(Chaetomium
thermophilum)
PF00071
(Ras)
4 MET C  59
LEU C   9
GLN C 178
PRO C 119
None
1.31A 3vkxA-5lddC:
undetectable
3vkxA-5lddC:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oes GLUTATHIONE
SYNTHETASE


(Solanum
tuberosum)
no annotation 4 MET A 458
LEU A 435
GLN A  76
TYR A 140
None
1.32A 3vkxA-5oesA:
undetectable
3vkxA-5oesA:
16.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5tup PROLIFERATING CELL
NUCLEAR ANTIGEN


(Aspergillus
fumigatus)
PF00705
(PCNA_N)
PF02747
(PCNA_C)
4 MET A  40
LEU A  47
PRO A 234
TYR A 249
None
0.64A 3vkxA-5tupA:
36.6
3vkxA-5tupA:
53.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vu2 E1 ENVELOPE
GLYCOPROTEIN


(Chikungunya
virus)
no annotation 4 PRO M  58
GLN M 102
PRO M  86
TYR M  93
None
1.19A 3vkxA-5vu2M:
undetectable
3vkxA-5vu2M:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y1i CYTOCHROME P450

(Streptomyces
graminofaciens)
PF00067
(p450)
4 MET A 256
LEU A 294
PRO A  31
TYR A 293
HEM  A 501 (-4.8A)
None
None
None
0.99A 3vkxA-5y1iA:
undetectable
3vkxA-5y1iA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b4o GLUTATHIONE
REDUCTASE


(Enterococcus
faecalis)
no annotation 4 MET A 414
PRO A 346
GLN A 386
PRO A 376
None
1.33A 3vkxA-6b4oA:
undetectable
3vkxA-6b4oA:
19.91