SIMILAR PATTERNS OF AMINO ACIDS FOR 3VAS_A_ADNA401_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) |
PF00089(Trypsin) | 5 | LEU A 64GLY A 197GLY A 196LEU A 106GLY A 142 | None | 1.01A | 3vasA-1a5iA:undetectable | 3vasA-1a5iA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cwv | INVASIN (Yersiniapseudotuberculosis) |
PF02369(Big_1)PF07979(Intimin_C)PF09134(Invasin_D3) | 5 | ILE A 750LEU A 721GLY A 715GLY A 766ASN A 767 | None | 0.89A | 3vasA-1cwvA:undetectable | 3vasA-1cwvA:20.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1dgm | ADENOSINE KINASE (Toxoplasmagondii) |
PF00294(PfkB) | 8 | ASN A 20ASP A 24GLY A 68GLY A 69ASN A 73LEU A 142GLY A 315ASP A 318 | ADN A 375 ( 3.8A)ADN A 375 (-2.9A)ADN A 375 ( 4.5A)ADN A 375 (-2.9A)ADN A 375 ( 4.9A)NoneACY A 370 (-3.1A)ADN A 375 ( 3.1A) | 0.64A | 3vasA-1dgmA:41.4 | 3vasA-1dgmA:31.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1dgm | ADENOSINE KINASE (Toxoplasmagondii) |
PF00294(PfkB) | 9 | ASP A 24LEU A 46GLY A 68GLY A 69ASN A 73THR A 140LEU A 142GLY A 315ASP A 318 | ADN A 375 (-2.9A)NoneADN A 375 ( 4.5A)ADN A 375 (-2.9A)ADN A 375 ( 4.9A)ADN A 375 ( 4.9A)NoneACY A 370 (-3.1A)ADN A 375 ( 3.1A) | 0.72A | 3vasA-1dgmA:41.4 | 3vasA-1dgmA:31.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h3g | CYCLOMALTODEXTRINASE (Flavobacteriumsp. 92) |
PF00128(Alpha-amylase)PF09087(Cyc-maltodext_N)PF10438(Cyc-maltodext_C) | 5 | ILE A 112GLY A 144ASN A 119LEU A 170GLY A 476 | None CA A 700 (-3.9A) CA A 700 (-2.9A)NoneNone | 1.05A | 3vasA-1h3gA:undetectable | 3vasA-1h3gA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j1w | ISOCITRATEDEHYDROGENASE (Azotobactervinelandii) |
PF03971(IDH) | 5 | ASN A 79ILE A 568GLY A 574GLY A 575GLY A 141 | None | 0.90A | 3vasA-1j1wA:undetectable | 3vasA-1j1wA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kb0 | QUINOHEMOPROTEINALCOHOLDEHYDROGENASE (Comamonastestosteroni) |
PF13360(PQQ_2)PF13442(Cytochrome_CBB3) | 5 | ILE A 192LEU A 288GLY A 262GLY A 242GLY A 182 | NoneNoneNoneNonePQQ A1800 (-3.2A) | 0.87A | 3vasA-1kb0A:undetectable | 3vasA-1kb0A:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kj9 | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE 2 (Escherichiacoli) |
PF02222(ATP-grasp) | 5 | ASP A 213ILE A 315GLY A 214VAL A 312LEU A 263 | None | 1.01A | 3vasA-1kj9A:3.6 | 3vasA-1kj9A:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pgj | 6-PHOSPHOGLUCONATEDEHYDROGENASE (Trypanosomabrucei) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | ASN A 175LEU A 348GLY A 146GLY A 145LEU A 359 | None | 1.05A | 3vasA-1pgjA:undetectable | 3vasA-1pgjA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q51 | MENB (Mycobacteriumtuberculosis) |
PF00378(ECH_1) | 5 | ILE A 143LEU A 73GLY A 161GLY A 162GLY A 196 | NoneNoneCAA A 501 (-3.3A)NoneNone | 1.06A | 3vasA-1q51A:3.7 | 3vasA-1q51A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rk2 | RIBOKINASE (Escherichiacoli) |
PF00294(PfkB) | 5 | ASP A 16GLY A 41GLY A 42ASN A 46ASP A 255 | RIB A 311 (-2.8A)RIB A 311 (-3.3A)RIB A 311 (-3.4A)RIB A 311 (-3.3A)RIB A 311 (-3.1A) | 0.34A | 3vasA-1rk2A:33.0 | 3vasA-1rk2A:25.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1txk | GLUCANS BIOSYNTHESISPROTEIN G (Escherichiacoli) |
PF04349(MdoG) | 5 | ILE A 385LEU A 250GLY A 161VAL A 159LEU A 168 | None | 1.01A | 3vasA-1txkA:undetectable | 3vasA-1txkA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tz6 | PUTATIVE SUGARKINASE (Salmonellaenterica) |
PF00294(PfkB) | 6 | ASP A 16GLY A 30GLY A 31ASN A 35GLY A 249ASP A 252 | AIS A 402 (-2.5A)AIS A 402 ( 4.2A)AIS A 402 (-3.8A)AIS A 402 (-3.9A)AIS A 402 ( 4.5A)AIS A 402 (-3.0A) | 0.43A | 3vasA-1tz6A:31.2 | 3vasA-1tz6A:27.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ua4 | ADP-DEPENDENTGLUCOKINASE (Pyrococcusfuriosus) |
PF04587(ADP_PFK_GK) | 5 | ASP A 34GLY A 111GLY A 112GLY A 437ASP A 440 | GLC A1457 ( 2.8A)GLC A1457 ( 3.5A)GLC A1457 ( 3.7A)BGC A2457 ( 4.0A)BGC A2457 ( 2.7A) | 0.49A | 3vasA-1ua4A:24.4 | 3vasA-1ua4A:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1urj | MAJOR DNA-BINDINGPROTEIN (Humanalphaherpesvirus1) |
PF00747(Viral_DNA_bp) | 5 | ILE A 985LEU A 771GLY A 534ASN A 380GLY A 531 | None | 1.05A | 3vasA-1urjA:undetectable | 3vasA-1urjA:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v19 | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermusthermophilus) |
PF00294(PfkB) | 6 | LEU A 170GLY A 33GLY A 34ASN A 38GLY A 248ASP A 251 | None | 0.83A | 3vasA-1v19A:28.4 | 3vasA-1v19A:24.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v19 | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermusthermophilus) |
PF00294(PfkB) | 6 | LEU A 170GLY A 34ASN A 38LEU A 138GLY A 248ASP A 251 | None | 1.07A | 3vasA-1v19A:28.4 | 3vasA-1v19A:24.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v3t | LEUKOTRIENE B412-HYDROXYDEHYDROGENASE/PROSTAGLANDIN15-KETO REDUCTASE (Cavia porcellus) |
PF00107(ADH_zinc_N)PF16884(ADH_N_2) | 5 | ILE A 296LEU A 287GLY A 152GLY A 155THR A 121 | NoneNoneNAP A1350 (-3.3A)NoneNone | 1.01A | 3vasA-1v3tA:5.8 | 3vasA-1v3tA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xrs | D-LYSINE5,6-AMINOMUTASEALPHA SUBUNIT (Acetoanaerobiumsticklandii) |
PF09043(Lys-AminoMut_A) | 5 | ILE A 468LEU A 473GLY A 484GLY A 483THR A 476 | None | 0.97A | 3vasA-1xrsA:undetectable | 3vasA-1xrsA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2abq | FRUCTOSE 1-PHOSPHATEKINASE (Bacillushalodurans) |
PF00294(PfkB) | 6 | ASP A 12GLY A 36GLY A 37ASN A 41GLY A 246ASP A 249 | None | 0.38A | 3vasA-2abqA:26.1 | 3vasA-2abqA:24.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2afb | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermotogamaritima) |
PF00294(PfkB) | 6 | LEU A 171GLY A 32GLY A 33ASN A 37GLY A 277ASP A 280 | None | 0.92A | 3vasA-2afbA:27.4 | 3vasA-2afbA:24.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2afb | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermotogamaritima) |
PF00294(PfkB) | 6 | LEU A 171GLY A 33ASN A 37LEU A 139GLY A 277ASP A 280 | None | 1.04A | 3vasA-2afbA:27.4 | 3vasA-2afbA:24.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ajr | SUGAR KINASE, PFKBFAMILY (Thermotogamaritima) |
PF00294(PfkB) | 5 | ASN A 8ASP A 12GLY A 39GLY A 40GLY A 258 | NoneACT A 321 (-3.1A)ACT A 321 ( 4.3A)ACT A 321 (-3.9A)None | 0.90A | 3vasA-2ajrA:24.9 | 3vasA-2ajrA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ajr | SUGAR KINASE, PFKBFAMILY (Thermotogamaritima) |
PF00294(PfkB) | 6 | ASP A 12GLY A 39GLY A 40ASN A 44GLY A 258ASP A 261 | ACT A 321 (-3.1A)ACT A 321 ( 4.3A)ACT A 321 (-3.9A)ACT A 321 (-3.9A)NoneNone | 0.42A | 3vasA-2ajrA:24.9 | 3vasA-2ajrA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c49 | SUGAR KINASE MJ0406 (Methanocaldococcusjannaschii) |
PF00294(PfkB) | 5 | ASP A 17GLY A 42GLY A 43ASN A 47ASP A 247 | ADN A1301 (-2.8A)ADN A1301 (-3.4A)ADN A1301 (-3.3A)ADN A1301 (-3.4A)ADN A1301 (-2.9A) | 0.32A | 3vasA-2c49A:28.9 | 3vasA-2c49A:25.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c49 | SUGAR KINASE MJ0406 (Methanocaldococcusjannaschii) |
PF00294(PfkB) | 5 | ASP A 17GLY A 42GLY A 43ASN A 47GLY A 244 | ADN A1301 (-2.8A)ADN A1301 (-3.4A)ADN A1301 (-3.3A)ADN A1301 (-3.4A)None | 0.50A | 3vasA-2c49A:28.9 | 3vasA-2c49A:25.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2i6b | ADENOSINE KINASE (Homo sapiens) |
PF00294(PfkB) | 7 | ASN A 14ASP A 18GLY A 63GLY A 64ASN A 68LEU A 138ASP A 300 | 89I A 500 (-4.0A)NoneNone89I A 500 (-3.5A)None89I A 500 (-4.4A)None | 0.53A | 3vasA-2i6bA:41.7 | 3vasA-2i6bA:36.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2i6b | ADENOSINE KINASE (Homo sapiens) |
PF00294(PfkB) | 6 | ASN A 14GLY A 64ASN A 68LEU A 138GLY A 297ASP A 300 | 89I A 500 (-4.0A)89I A 500 (-3.5A)None89I A 500 (-4.4A)NoneNone | 0.68A | 3vasA-2i6bA:41.7 | 3vasA-2i6bA:36.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2i6b | ADENOSINE KINASE (Homo sapiens) |
PF00294(PfkB) | 7 | ASP A 18LEU A 40GLY A 63GLY A 64ASN A 68LEU A 138ASP A 300 | None89I A 500 ( 4.8A)None89I A 500 (-3.5A)None89I A 500 (-4.4A)None | 0.62A | 3vasA-2i6bA:41.7 | 3vasA-2i6bA:36.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2i6b | ADENOSINE KINASE (Homo sapiens) |
PF00294(PfkB) | 6 | LEU A 40GLY A 64ASN A 68LEU A 138GLY A 297ASP A 300 | 89I A 500 ( 4.8A)89I A 500 (-3.5A)None89I A 500 (-4.4A)NoneNone | 1.03A | 3vasA-2i6bA:41.7 | 3vasA-2i6bA:36.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i6d | RNAMETHYLTRANSFERASE,TRMH FAMILY (Porphyromonasgingivalis) |
PF00588(SpoU_methylase) | 5 | LEU A 166GLY A 134GLY A 107THR A 162LEU A 104 | None | 1.00A | 3vasA-2i6dA:2.7 | 3vasA-2i6dA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jg5 | FRUCTOSE 1-PHOSPHATEKINASE (Staphylococcusaureus) |
PF00294(PfkB) | 5 | GLY A 36GLY A 37ASN A 41GLY A 246ASP A 249 | None | 0.49A | 3vasA-2jg5A:25.4 | 3vasA-2jg5A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nyp | BETA-LACTAMASE II (Bacillus cereus) |
PF00753(Lactamase_B) | 5 | ILE A 193LEU A 226GLY A 209THR A 222LEU A 178 | NoneNone ZN A 302 ( 4.8A)NoneNone | 0.94A | 3vasA-2nypA:undetectable | 3vasA-2nypA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qcv | PUTATIVE5-DEHYDRO-2-DEOXYGLUCONOKINASE (Bacillushalodurans) |
PF00294(PfkB) | 6 | ASP A 22GLY A 43GLY A 44ASN A 48GLY A 269ASP A 272 | NoneNoneNoneNoneNonePGE A 332 (-3.6A) | 0.40A | 3vasA-2qcvA:32.2 | 3vasA-2qcvA:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y93 | CIS-2,3-DIHYDROBIPHENYL-2,3-DIOLDEHYDROGENASE (Comamonastestosteroni) |
PF00106(adh_short) | 5 | GLY A 185ASN A 143THR A 189LEU A 225GLY A 150 | None | 1.03A | 3vasA-2y93A:6.2 | 3vasA-2y93A:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z84 | UFM1-SPECIFICPROTEASE 1 (Mus musculus) |
PF07910(Peptidase_C78) | 5 | ASP A 152LEU A 127GLY A 149GLY A 148LEU A 121 | None | 0.94A | 3vasA-2z84A:undetectable | 3vasA-2z84A:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zec | TRYPTASE BETA 2 (Homo sapiens) |
PF00089(Trypsin) | 5 | LEU A 71GLY A 211GLY A 210LEU A 110GLY A 146 | None | 1.06A | 3vasA-2zecA:undetectable | 3vasA-2zecA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1r | RIBOKINASE, PUTATIVE (Burkholderiathailandensis) |
PF00294(PfkB) | 6 | ASP A 12GLY A 47GLY A 48ASN A 52GLY A 250ASP A 253 | AMP A 501 (-2.9A)AMP A 501 ( 3.7A)AMP A 501 (-3.3A)AMP A 501 (-3.3A)AMP A 501 (-3.4A)AMP A 501 (-2.8A) | 0.58A | 3vasA-3b1rA:27.4 | 3vasA-3b1rA:24.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b3l | KETOHEXOKINASE (Homo sapiens) |
PF00294(PfkB) | 5 | GLY A 40GLY A 41ASN A 45GLY A 255ASP A 258 | None | 0.56A | 3vasA-3b3lA:27.1 | 3vasA-3b3lA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cji | POLYPROTEIN (Senecavirus A) |
PF00073(Rhv)no annotation | 5 | GLY A 197GLY A 196THR C 237LEU C 141GLY C 223 | None | 0.96A | 3vasA-3cjiA:undetectable | 3vasA-3cjiA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewm | UNCHARACTERIZEDSUGAR KINASE PH1459 (Pyrococcushorikoshii) |
PF00294(PfkB) | 5 | ASP A 13GLY A 33GLY A 34ASN A 38ASP A 247 | None | 0.37A | 3vasA-3ewmA:31.1 | 3vasA-3ewmA:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewm | UNCHARACTERIZEDSUGAR KINASE PH1459 (Pyrococcushorikoshii) |
PF00294(PfkB) | 5 | ASP A 13GLY A 33GLY A 34ASN A 38VAL A 90 | None | 0.45A | 3vasA-3ewmA:31.1 | 3vasA-3ewmA:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewm | UNCHARACTERIZEDSUGAR KINASE PH1459 (Pyrococcushorikoshii) |
PF00294(PfkB) | 6 | GLY A 33GLY A 34ASN A 38LEU A 103GLY A 244ASP A 247 | None | 0.90A | 3vasA-3ewmA:31.1 | 3vasA-3ewmA:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewm | UNCHARACTERIZEDSUGAR KINASE PH1459 (Pyrococcushorikoshii) |
PF00294(PfkB) | 5 | LEU A 167GLY A 33GLY A 34ASN A 38VAL A 90 | None | 0.97A | 3vasA-3ewmA:31.1 | 3vasA-3ewmA:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3go7 | RIBOKINASE RBSK (Mycobacteriumtuberculosis) |
PF00294(PfkB) | 6 | ASP A 25GLY A 50GLY A 51ASN A 55GLY A 239ASP A 242 | RIB A 305 (-2.8A)RIB A 305 ( 3.7A)RIB A 305 (-3.1A)RIB A 305 (-3.2A)RIB A 305 ( 4.5A)RIB A 305 (-2.9A) | 0.39A | 3vasA-3go7A:27.5 | 3vasA-3go7A:24.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gre | SERINE/THREONINE-PROTEIN KINASE VPS15 (Saccharomycescerevisiae) |
no annotation | 5 | ASN A1347ILE A1317GLY A1295GLY A1272ASP A1273 | None | 0.97A | 3vasA-3greA:undetectable | 3vasA-3greA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hj6 | FRUCTOKINASE (Halothermothrixorenii) |
PF00294(PfkB) | 5 | ASP A 33GLY A 54GLY A 55ASN A 59ASP A 275 | None | 0.42A | 3vasA-3hj6A:29.1 | 3vasA-3hj6A:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hj6 | FRUCTOKINASE (Halothermothrixorenii) |
PF00294(PfkB) | 5 | LEU A 188GLY A 54GLY A 55ASN A 59ASP A 275 | None | 0.77A | 3vasA-3hj6A:29.1 | 3vasA-3hj6A:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3a | ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASE (Leptospirainterrogans) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 5 | ILE A 106GLY A 138GLY A 119LEU A 130GLY A 97 | NoneS2N A 260 (-3.8A)S2N A 260 ( 3.8A)NoneNone | 1.01A | 3vasA-3i3aA:undetectable | 3vasA-3i3aA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3y | CARBOHYDRATE KINASE (Klebsiellapneumoniae) |
PF00294(PfkB) | 5 | ASP A 12GLY A 37GLY A 38ASN A 42THR A 107 | None | 0.71A | 3vasA-3i3yA:25.9 | 3vasA-3i3yA:26.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3y | CARBOHYDRATE KINASE (Klebsiellapneumoniae) |
PF00294(PfkB) | 5 | GLY A 37GLY A 38ASN A 42GLY A 229ASP A 232 | None | 0.59A | 3vasA-3i3yA:25.9 | 3vasA-3i3yA:26.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3icq | EXPORTIN-T (Schizosaccharomycespombe) |
PF08389(Xpo1) | 5 | ILE T 920LEU T 886GLY T 872GLY T 871THR T 883 | None | 0.93A | 3vasA-3icqT:undetectable | 3vasA-3icqT:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3in1 | UNCHARACTERIZEDSUGAR KINASE YDJH (Escherichiacoli) |
PF00294(PfkB) | 6 | ILE A 172GLY A 41GLY A 42ASN A 46GLY A 257ASP A 260 | NoneNoneNoneNone NA A 411 ( 4.9A)None | 0.87A | 3vasA-3in1A:30.6 | 3vasA-3in1A:26.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kzh | PROBABLE SUGARKINASE (Clostridiumperfringens) |
PF00294(PfkB) | 5 | GLY A 42GLY A 43ASN A 47GLY A 254ASP A 257 | None | 0.34A | 3vasA-3kzhA:27.3 | 3vasA-3kzhA:23.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ll1 | GRIFFITHSIN (Griffithsia sp.Q66D336) |
PF01419(Jacalin) | 5 | ILE A 63LEU A 114GLY A 87GLY A 86LEU A 111 | None | 0.82A | 3vasA-3ll1A:undetectable | 3vasA-3ll1A:16.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3loo | ANOPHELES GAMBIAEADENOSINE KINASE (Anophelesgambiae) |
PF00294(PfkB) | 9 | ASN A 14ASP A 18LEU A 40GLY A 63GLY A 64ASN A 68LEU A 137GLY A 297ASP A 300 | B4P A 349 ( 4.0A)B4P A 349 (-2.8A)NoneB4P A 349 ( 3.8A)B4P A 349 (-3.5A)B4P A 349 (-3.6A)NoneB4P A 349 (-2.9A)B4P A 349 (-3.4A) | 0.32A | 3vasA-3looA:47.5 | 3vasA-3looA:38.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lsc | TRIAZINE HYDROLASE (Paenarthrobacteraurescens) |
PF01979(Amidohydro_1) | 5 | LEU A 441GLY A 122GLY A 121VAL A 431LEU A 116 | None | 0.99A | 3vasA-3lscA:undetectable | 3vasA-3lscA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwf | PUTATIVETRANSCRIPTIONALREGULATOR (Listeriainnocua) |
PF02082(Rrf2) | 5 | ILE A 79LEU A 83GLY A 53THR A 82GLY A 69 | None | 1.03A | 3vasA-3lwfA:undetectable | 3vasA-3lwfA:19.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3otx | ADENOSINE KINASE,PUTATIVE (Trypanosomabrucei) |
PF00294(PfkB) | 8 | ASN A 13ASP A 17LEU A 39GLY A 62GLY A 63ASN A 67LEU A 138ASP A 299 | AP5 A 346 (-4.1A)AP5 A 346 (-2.8A)NoneAP5 A 346 (-3.6A)AP5 A 346 (-3.5A)AP5 A 346 (-3.4A)NoneAP5 A 346 ( 3.2A) | 0.35A | 3vasA-3otxA:45.4 | 3vasA-3otxA:30.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pl2 | SUGAR KINASE,RIBOKINASE FAMILY (Corynebacteriumglutamicum) |
PF00294(PfkB) | 6 | ASP A 19GLY A 40GLY A 41ASN A 45GLY A 261ASP A 264 | None | 0.42A | 3vasA-3pl2A:31.4 | 3vasA-3pl2A:24.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pqu | TRANSFERRIN BINDINGPROTEIN B (Actinobacillussuis) |
PF01298(TbpB_B_D)PF17483(TbpB_C)PF17484(TbpB_A) | 5 | ASN A 541ILE A 349GLY A 553GLY A 554THR A 347 | None | 0.84A | 3vasA-3pquA:undetectable | 3vasA-3pquA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q1y | LIN2199 PROTEIN (Listeriainnocua) |
PF00294(PfkB) | 5 | ASN A 8ASP A 12GLY A 37GLY A 38GLY A 248 | None | 0.93A | 3vasA-3q1yA:25.5 | 3vasA-3q1yA:23.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q1y | LIN2199 PROTEIN (Listeriainnocua) |
PF00294(PfkB) | 5 | ASP A 12GLY A 37GLY A 38GLY A 248ASP A 251 | None | 0.60A | 3vasA-3q1yA:25.5 | 3vasA-3q1yA:23.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qfk | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF00149(Metallophos)PF02872(5_nucleotid_C) | 5 | ASP A 56ILE A 151GLY A 55LEU A 103GLY A 192 | MN A 513 ( 2.7A)NoneNoneNoneNone | 1.03A | 3vasA-3qfkA:undetectable | 3vasA-3qfkA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ry7 | RIBOKINASE (Staphylococcusaureus) |
PF00294(PfkB) | 5 | ASP A 14GLY A 40GLY A 41ASN A 45ASP A 254 | GOL A 401 (-3.1A)GOL A 401 ( 3.7A)GOL A 401 (-3.8A)GOL A 401 (-3.9A)None | 0.57A | 3vasA-3ry7A:27.6 | 3vasA-3ry7A:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tjr | SHORT CHAINDEHYDROGENASE (Mycobacteriumavium) |
PF00106(adh_short) | 5 | ASN A 181ILE A 142LEU A 130GLY A 3LEU A 134 | None | 0.82A | 3vasA-3tjrA:6.4 | 3vasA-3tjrA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tv2 | FUMARATE HYDRATASE,CLASS II (Burkholderiapseudomallei) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 5 | ILE A 191GLY A 369GLY A 368THR A 286GLY A 277 | None | 1.00A | 3vasA-3tv2A:undetectable | 3vasA-3tv2A:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ubo | ADENOSINE KINASE (Sinorhizobiummeliloti) |
PF00294(PfkB) | 10 | ASN A 11ASP A 15LEU A 37GLY A 58GLY A 59ASN A 63THR A 129LEU A 131GLY A 275ASP A 278 | ADN A 353 (-3.7A)ADN A 353 (-2.8A)NoneADN A 353 (-3.3A)ADN A 353 (-3.2A)ADN A 353 (-3.4A)ADN A 353 (-3.3A)NoneADN A 353 (-3.7A)ADN A 353 (-3.3A) | 0.54A | 3vasA-3uboA:40.0 | 3vasA-3uboA:25.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ubo | ADENOSINE KINASE (Sinorhizobiummeliloti) |
PF00294(PfkB) | 6 | ASP A 15LEU A 131ASN A 63THR A 129GLY A 275ASP A 278 | ADN A 353 (-2.8A)NoneADN A 353 (-3.4A)ADN A 353 (-3.3A)ADN A 353 (-3.7A)ADN A 353 (-3.3A) | 1.39A | 3vasA-3uboA:40.0 | 3vasA-3uboA:25.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4y | SERINE/THREONINE-PROTEIN PHOSPHATASEPP1-ALPHA CATALYTICSUBUNIT (Homo sapiens) |
PF00149(Metallophos)PF16891(STPPase_N) | 5 | ASP A 64LEU A 263ASN A 124THR A 265GLY A 123 | MN A 402 (-3.0A)None MN A 401 (-2.7A)NoneNone | 1.06A | 3vasA-3v4yA:undetectable | 3vasA-3v4yA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b8s | ADP-DEPENDENTGLUCOKINASE (Thermococcuslitoralis) |
PF04587(ADP_PFK_GK) | 5 | ASP A 42GLY A 119GLY A 120GLY A 448ASP A 451 | GLC A 468 (-2.7A)GLC A 468 (-3.5A)GLC A 468 (-3.6A)GLC A 468 ( 4.0A)GLC A 468 (-2.9A) | 0.41A | 3vasA-4b8sA:21.2 | 3vasA-4b8sA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e3a | SUGAR KINASE PROTEIN (Rhizobium etli) |
PF00294(PfkB) | 10 | ASN A 9ASP A 13LEU A 35GLY A 56GLY A 57ASN A 61THR A 127LEU A 129GLY A 273ASP A 276 | ADN A 500 (-3.8A)ADN A 500 (-2.7A)NoneADN A 500 (-3.5A)ADN A 500 (-3.7A)ADN A 500 (-3.5A)ADN A 500 (-3.0A)NoneADN A 500 (-3.9A)ADN A 500 (-2.8A) | 0.43A | 3vasA-4e3aA:40.3 | 3vasA-4e3aA:28.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e3a | SUGAR KINASE PROTEIN (Rhizobium etli) |
PF00294(PfkB) | 6 | ASP A 13LEU A 129ASN A 61THR A 127GLY A 273ASP A 276 | ADN A 500 (-2.7A)NoneADN A 500 (-3.5A)ADN A 500 (-3.0A)ADN A 500 (-3.9A)ADN A 500 (-2.8A) | 1.32A | 3vasA-4e3aA:40.3 | 3vasA-4e3aA:28.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gm6 | PFKB FAMILYCARBOHYDRATE KINASE (Listeria grayi) |
PF00294(PfkB) | 6 | LEU A 172GLY A 33GLY A 34ASN A 38GLY A 267ASP A 270 | NoneGOL A 401 ( 4.1A)GOL A 401 (-3.7A)GOL A 401 (-4.4A)GOL A 401 ( 4.5A)GOL A 401 (-3.0A) | 0.79A | 3vasA-4gm6A:29.2 | 3vasA-4gm6A:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4htg | PORPHOBILINOGENDEAMINASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF01379(Porphobil_deam)PF03900(Porphobil_deamC) | 5 | ILE A 15LEU A 34GLY A 214THR A 30LEU A 231 | None | 0.96A | 3vasA-4htgA:undetectable | 3vasA-4htgA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4il1 | CALMODULIN,CALCINEURIN SUBUNITB TYPE 1,SERINE/THREONINE-PROTEIN PHOSPHATASE 2BCATALYTIC SUBUNITALPHA ISOFORM (Rattusnorvegicus) |
PF00149(Metallophos)PF13499(EF-hand_7) | 5 | ASP A 423LEU A 635ASN A 483THR A 637GLY A 482 | None | 1.02A | 3vasA-4il1A:undetectable | 3vasA-4il1A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4il5 | CYSTEINE SYNTHASE (Entamoebahistolytica) |
PF00291(PALP) | 5 | ASN A 88ILE A 106GLY A 62THR A 85GLY A 97 | LLP A 58 (-3.9A)NoneLLP A 58 ( 3.8A)ILE A 401 (-4.2A)None | 1.00A | 3vasA-4il5A:3.2 | 3vasA-4il5A:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ora | SERINE/THREONINE-PROTEIN PHOSPHATASE 2BCATALYTIC SUBUNITBETA ISOFORM (Homo sapiens) |
PF00149(Metallophos) | 5 | ASP A 99LEU A 311ASN A 159THR A 313GLY A 158 | FE A 602 ( 4.1A)None ZN A 601 (-3.2A)NoneNone | 1.04A | 3vasA-4oraA:undetectable | 3vasA-4oraA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4orb | SERINE/THREONINE-PROTEIN PHOSPHATASE 2BCATALYTIC SUBUNITALPHA ISOFORM (Mus musculus) |
PF00149(Metallophos) | 5 | ASP A 90LEU A 302ASN A 150THR A 304GLY A 149 | FE A 602 ( 3.4A)None ZN A 601 (-2.7A)NoneNone | 1.01A | 3vasA-4orbA:undetectable | 3vasA-4orbA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvv | ADENOSINE KINASE (Mycobacteriumtuberculosis) |
PF00294(PfkB) | 6 | ASP A 12GLY A 47GLY A 48ASN A 52GLY A 254ASP A 257 | HO4 A 401 (-2.4A)HO4 A 401 (-3.5A)HO4 A 401 (-3.5A)HO4 A 401 (-3.8A)HO4 A 401 ( 4.3A)HO4 A 401 (-3.3A) | 0.61A | 3vasA-4pvvA:28.0 | 3vasA-4pvvA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjm | RIBOKINASE:CARBOHYDRATE KINASE, PFKB (Brucellaabortus) |
PF00294(PfkB) | 6 | ASP A 11GLY A 29GLY A 30ASN A 34GLY A 246ASP A 249 | NoneNoneNoneNoneANP A 401 (-3.3A)ANP A 401 ( 4.3A) | 0.57A | 3vasA-4wjmA:30.0 | 3vasA-4wjmA:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjm | RIBOKINASE:CARBOHYDRATE KINASE, PFKB (Brucellaabortus) |
PF00294(PfkB) | 5 | LEU A 162GLY A 29GLY A 30ASN A 34ASP A 249 | NoneNoneNoneNoneANP A 401 ( 4.3A) | 0.89A | 3vasA-4wjmA:30.0 | 3vasA-4wjmA:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x8f | RIBOKINASE (Vibrio cholerae) |
PF00294(PfkB) | 5 | ASP A 13GLY A 38GLY A 39ASN A 43ASP A 252 | None | 0.57A | 3vasA-4x8fA:29.9 | 3vasA-4x8fA:24.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zb3 | NUDIX HYDROLASE 7 (Arabidopsisthaliana) |
PF00293(NUDIX) | 5 | ILE A 55LEU A 38GLY A 20GLY A 52LEU A 42 | None | 0.88A | 3vasA-4zb3A:undetectable | 3vasA-4zb3A:24.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zda | ISOCITRATEDEHYDROGENASE (NADP)ICD2 (Mycolicibacteriumsmegmatis) |
PF03971(IDH) | 5 | ASN A 81ILE A 571GLY A 577GLY A 578GLY A 143 | None | 1.01A | 3vasA-4zdaA:undetectable | 3vasA-4zdaA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b7i | CRISPR-ASSOCIATEDNUCLEASE/HELICASECAS3 SUBTYPEI-F/YPEST (Pseudomonasaeruginosa) |
no annotation | 5 | LEU A 353GLY A 265LEU A 349GLY A 181ASP A 182 | None | 0.91A | 3vasA-5b7iA:undetectable | 3vasA-5b7iA:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c41 | RIBOKINASE (Homo sapiens) |
PF00294(PfkB) | 6 | ASP A 27GLY A 52GLY A 53ASN A 57GLY A 266ASP A 269 | NoneNoneNoneNoneACP A 401 ( 4.1A) NA A 403 ( 4.7A) | 0.47A | 3vasA-5c41A:32.9 | 3vasA-5c41A:24.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5de0 | DEFERROCHELATASE (Vibrio cholerae) |
PF04261(Dyp_perox) | 5 | ILE A 228VAL A 217LEU A 260GLY A 145ASP A 144 | HEM A 401 ( 4.7A)HEM A 401 (-4.3A)HEM A 401 ( 4.5A)HEM A 401 (-3.2A)HEM A 401 ( 4.7A) | 0.96A | 3vasA-5de0A:undetectable | 3vasA-5de0A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey7 | FRUCTOKINASE (Vibrio cholerae) |
PF00294(PfkB) | 7 | ASP A 30GLY A 44GLY A 45ASN A 49VAL A 101GLY A 263ASP A 266 | None | 0.56A | 3vasA-5ey7A:31.3 | 3vasA-5ey7A:23.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fyn | PUUMALA VIRUS GNGLYCOPROTEIN (Puumalaorthohantavirus) |
PF01567(Hanta_G1) | 5 | ILE A 347LEU A 338GLY A 323THR A 365GLY A 351 | None | 0.81A | 3vasA-5fynA:undetectable | 3vasA-5fynA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5it9 | RIBOSOMAL PROTEINRACK1 (Kluyveromyceslactis) |
PF01092(Ribosomal_S6e) | 5 | ASN g 18ILE g 44GLY g 19THR g 42GLY g 311 | G 21406 ( 4.1A)NoneNoneNoneNone | 0.86A | 3vasA-5it9g:undetectable | 3vasA-5it9g:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k6w | PROTEIN SIDEKICK-1 (Mus musculus) |
PF07679(I-set)PF13927(Ig_3) | 5 | ILE A 284GLY A 367GLY A 366ASN A 364GLY A 314 | None | 1.03A | 3vasA-5k6wA:undetectable | 3vasA-5k6wA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o0j | ADP-DEPENDENTGLUCOKINASE (Pyrococcushorikoshii) |
no annotation | 5 | ASP A 37GLY A 114GLY A 115GLY A 440ASP A 443 | GLC A 503 (-2.7A)GLC A 503 (-3.5A)GLC A 503 (-3.7A)GLC A 503 ( 4.1A)GLC A 503 (-2.6A) | 0.49A | 3vasA-5o0jA:23.9 | 3vasA-5o0jA:11.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5od2 | BIFUNCTIONALADP-SPECIFICGLUCOKINASE/PHOSPHOFRUCTOKINASE (Methanocaldococcusjannaschii) |
no annotation | 5 | ASP A 28GLY A 106GLY A 107GLY A 439ASP A 442 | GLC A 501 (-2.7A)GLC A 501 (-3.2A)GLC A 501 (-3.7A)PO4 A 504 (-3.1A)GLC A 501 ( 2.6A) | 0.50A | 3vasA-5od2A:20.8 | 3vasA-5od2A:14.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xpg | UNCHARACTERIZEDPROTEIN (Thermusthermophilus) |
no annotation | 5 | LEU A 527GLY A 476THR A 526LEU A 473GLY A 488 | None | 1.03A | 3vasA-5xpgA:undetectable | 3vasA-5xpgA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xra | CANNABINOID RECEPTOR1,FLAVODOXIN,CANNABINOID RECEPTOR 1 (Desulfovibriovulgaris;Homo sapiens) |
PF00001(7tm_1)PF00258(Flavodoxin_1) | 5 | ILE A1022LEU A1054GLY A1030VAL A1033LEU A1052 | None | 0.96A | 3vasA-5xraA:5.3 | 3vasA-5xraA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ybw | ASPARTATE RACEMASE (Scapharcabroughtonii) |
no annotation | 5 | LEU A 209GLY A 169THR A 202LEU A 176GLY A 193 | NoneNoneNoneNoneLLP A 63 ( 3.5A) | 1.04A | 3vasA-5ybwA:undetectable | 3vasA-5ybwA:13.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cw5 | RIBOKINASE (Cryptococcusneoformans) |
no annotation | 6 | ASP A 16GLY A 41GLY A 42ASN A 46GLY A 270ASP A 273 | GOL A 400 (-2.8A)GOL A 400 (-3.5A)GOL A 400 (-3.3A)GOL A 400 (-3.3A)NoneNone | 0.50A | 3vasA-6cw5A:30.7 | 3vasA-6cw5A:12.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fks | - (-) |
no annotation | 5 | ILE A 230VAL A 219LEU A 262GLY A 144ASP A 143 | HEM A 301 ( 4.2A)HEM A 301 (-3.7A)HEM A 301 ( 4.2A)GOL A 303 (-2.9A)GOL A 303 ( 2.3A) | 1.06A | 3vasA-6fksA:undetectable | 3vasA-6fksA:undetectable |