SIMILAR PATTERNS OF AMINO ACIDS FOR 3V5W_A_8PRA701_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a5i PLASMINOGEN
ACTIVATOR

(Desmodus
rotundus) 		PF00089
(Trypsin) 		3 LEU A 210
MET A 207
ASP A 204
 None
 0.90A 3v5wA-1a5iA:
undetectable		 3v5wA-1a5iA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN

(Propionibacterium
freudenreichii) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding) 		3 LEU A 175
MET A 167
ASP A 199
 None
 0.86A 3v5wA-1e1cA:
undetectable		 3v5wA-1e1cA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ea9 CYCLOMALTODEXTRINASE

(Bacillus sp.
(in: Bacteria)) 		PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16657
(Malt_amylase_C) 		3 LEU C  84
MET C  56
ASP C  66
 None
 0.73A 3v5wA-1ea9C:
undetectable		 3v5wA-1ea9C:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jkw CYCLIN H

(Homo sapiens) 		PF00134
(Cyclin_N)
PF16899
(Cyclin_C_2) 		3 LEU A 206
MET A 255
ASP A 250
 None
 0.91A 3v5wA-1jkwA:
undetectable		 3v5wA-1jkwA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqk CARBON MONOXIDE
DEHYDROGENASE

(Rhodospirillum
rubrum) 		PF03063
(Prismane) 		3 LEU A 104
MET A 106
ASP A 147
 None
 0.89A 3v5wA-1jqkA:
undetectable		 3v5wA-1jqkA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p2z HEXON PROTEIN

(Human
mastadenovirus
C) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		3 LEU A 383
MET A 806
ASP A 882
 None
 0.86A 3v5wA-1p2zA:
undetectable		 3v5wA-1p2zA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rxt GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1

(Homo sapiens) 		PF01233
(NMT)
PF02799
(NMT_C) 		3 LEU A 387
MET A 381
ASP A 325
 None
 0.84A 3v5wA-1rxtA:
undetectable		 3v5wA-1rxtA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sr4 CYTOLETHAL
DISTENDING TOXIN
PROTEIN B

([Haemophilus]
ducreyi) 		PF03372
(Exo_endo_phos) 		3 LEU B  52
MET B  63
ASP B 199
 None
None
BR  B 523 ( 4.8A)
 0.83A 3v5wA-1sr4B:
undetectable		 3v5wA-1sr4B:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxj ACTIVATOR 1 37 KDA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF00004
(AAA)
PF08542
(Rep_fac_C) 		3 LEU B 209
MET B 202
ASP B 168
 None
AGS  B 802 (-4.7A)
None
 0.89A 3v5wA-1sxjB:
undetectable		 3v5wA-1sxjB:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v61 RAC/CDC42 GUANINE
NUCLEOTIDE EXCHANGE
FACTOR (GEF) 6

(Mus musculus) 		PF00169
(PH) 		3 LEU A 124
MET A 118
ASP A 113
 None
 0.85A 3v5wA-1v61A:
9.0		 3v5wA-1v61A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN

(Escherichia
coli) 		PF04257
(Exonuc_V_gamma) 		3 LEU C 394
MET C 396
ASP C 407
 None
 0.86A 3v5wA-1w36C:
undetectable		 3v5wA-1w36C:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x75 DNA GYRASE SUBUNIT A

(Escherichia
coli) 		PF00521
(DNA_topoisoIV) 		3 LEU A 417
MET A 423
ASP A 429
 None
 0.92A 3v5wA-1x75A:
undetectable		 3v5wA-1x75A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bpa PROTEIN (SUBUNIT OF
BACTERIOPHAGE
PHIX174)

(Escherichia
virus phiX174) 		PF02305
(Phage_F) 		3 LEU 1 416
MET 1  10
ASP 1  13
 None
 0.88A 3v5wA-2bpa1:
undetectable		 3v5wA-2bpa1:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lg1 A-KINASE ANCHOR
PROTEIN 13

(Homo sapiens) 		PF00169
(PH) 		3 LEU A 113
MET A  53
ASP A  48
 None
 0.78A 3v5wA-2lg1A:
9.0		 3v5wA-2lg1A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m0g SPLICING FACTOR U2AF
65 KDA SUBUNIT

(Homo sapiens) 		PF00076
(RRM_1) 		3 LEU B 380
MET B 446
ASP B 441
 None
 0.92A 3v5wA-2m0gB:
undetectable		 3v5wA-2m0gB:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2npn PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN

(Corynebacterium
diphtheriae) 		PF00590
(TP_methylase) 		3 LEU A 207
MET A 241
ASP A 186
 SAM  A4633 (-3.6A)
SAM  A4633 (-3.9A)
None
 0.73A 3v5wA-2npnA:
undetectable		 3v5wA-2npnA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2x HYPOTHETICAL PROTEIN

(Mesorhizobium
loti) 		PF13242
(Hydrolase_like) 		3 LEU A 174
MET A 166
ASP A  36
 None
 0.72A 3v5wA-2o2xA:
undetectable		 3v5wA-2o2xA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obe HEXON

(Human
mastadenovirus
E) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		3 LEU A 353
MET A 771
ASP A 847
 None
2HP  A1620 (-4.4A)
None
 0.85A 3v5wA-2obeA:
undetectable		 3v5wA-2obeA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oez UPF0289 PROTEIN
VP2528

(Vibrio
parahaemolyticus) 		PF07072
(ZapD) 		3 LEU A  62
MET A 102
ASP A  95
 None
 0.85A 3v5wA-2oezA:
3.2		 3v5wA-2oezA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okc TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF02384
(N6_Mtase)
PF12161
(HsdM_N) 		3 LEU A 123
MET A 125
ASP A 128
 None
 0.74A 3v5wA-2okcA:
undetectable		 3v5wA-2okcA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9h OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET

(Escherichia
coli) 		PF07244
(POTRA) 		3 LEU A  44
MET A  46
ASP A  52
 None
 0.89A 3v5wA-2v9hA:
undetectable		 3v5wA-2v9hA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x8r GLYCOSYL HYDROLASE

(Aspergillus
fumigatus) 		PF01183
(Glyco_hydro_25) 		3 LEU A  64
MET A  38
ASP A 201
 None
 0.79A 3v5wA-2x8rA:
undetectable		 3v5wA-2x8rA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xgo XCOGT

(Xanthomonas
campestris) 		PF13432
(TPR_16)
PF13844
(Glyco_transf_41) 		3 LEU A 499
MET A 504
ASP A 459
 None
 0.92A 3v5wA-2xgoA:
undetectable		 3v5wA-2xgoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xij METHYLMALONYL-COA
MUTASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding) 		3 LEU A 196
MET A 188
ASP A 220
 None
 0.87A 3v5wA-2xijA:
undetectable		 3v5wA-2xijA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y3a PHOSPHATIDYLINOSITOL
-4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT BETA ISOFORM

(Mus musculus) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
PF02192
(PI3K_p85B) 		3 LEU A 103
MET A  73
ASP A  88
 None
 0.87A 3v5wA-2y3aA:
undetectable		 3v5wA-2y3aA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zay RESPONSE REGULATOR
RECEIVER PROTEIN

(Desulfuromonas
acetoxidans) 		PF00072
(Response_reg) 		3 LEU A  55
MET A  12
ASP A  15
 None
 0.88A 3v5wA-2zayA:
undetectable		 3v5wA-2zayA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zba TRICHOTHECENE
3-O-ACETYLTRANSFERAS
E

(Fusarium
sporotrichioides) 		PF02458
(Transferase) 		3 LEU A 385
MET A 320
ASP A 169
 None
ZBA  A 463 (-3.8A)
None
 0.84A 3v5wA-2zbaA:
undetectable		 3v5wA-2zbaA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zux YESW PROTEIN

(Bacillus
subtilis) 		no annotation 3 LEU A 365
MET A 383
ASP A 386
 None
None
CA  A 637 (-2.9A)
 0.89A 3v5wA-2zuxA:
undetectable		 3v5wA-2zuxA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Bacillus
anthracis) 		PF02350
(Epimerase_2) 		3 LEU A 283
MET A 221
ASP A 324
 None
 0.92A 3v5wA-3beoA:
undetectable		 3v5wA-3beoA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bh2 ACETOACETATE
DECARBOXYLASE

(Clostridium
acetobutylicum) 		PF06314
(ADC) 		3 LEU A  71
MET A  65
ASP A 230
 None
 0.86A 3v5wA-3bh2A:
undetectable		 3v5wA-3bh2A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c1x HEPATOCYTE GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 LEU A1157
MET A1160
ASP A1164
 CKK  A1500 (-4.7A)
None
CKK  A1500 (-3.7A)
 0.61A 3v5wA-3c1xA:
20.1		 3v5wA-3c1xA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cqb PROBABLE PROTEASE
HTPX HOMOLOG

(Vibrio
parahaemolyticus) 		PF01435
(Peptidase_M48) 		3 LEU A  72
MET A  75
ASP A  78
 CL  A 105 ( 4.3A)
None
None
 0.89A 3v5wA-3cqbA:
undetectable		 3v5wA-3cqbA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3exh PYRUVATE
DEHYDROGENASE E1
COMPONENT SUBUNIT
BETA, MITOCHONDRIAL

(Homo sapiens) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		3 LEU B 308
MET B 302
ASP B 299
 None
 0.79A 3v5wA-3exhB:
undetectable		 3v5wA-3exhB:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5g MYOSIN HEAVY CHAIN
ISOFORM A

(Doryteuthis
pealeii) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF02736
(Myosin_N) 		3 LEU A 612
MET A 622
ASP A 435
 None
 0.84A 3v5wA-3i5gA:
3.1		 3v5wA-3i5gA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihy PHOSPHATIDYLINOSITOL
3-KINASE CATALYTIC
SUBUNIT TYPE 3

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka) 		3 LEU A 577
MET A 583
ASP A 550
 None
 0.87A 3v5wA-3ihyA:
3.7		 3v5wA-3ihyA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1

(Homo sapiens) 		PF01233
(NMT)
PF02799
(NMT_C) 		3 LEU A 441
MET A 435
ASP A 396
 None
 0.89A 3v5wA-3iu1A:
undetectable		 3v5wA-3iu1A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ixl ARYLMALONATE
DECARBOXYLASE

(Bordetella
bronchiseptica) 		no annotation 3 LEU A  99
MET A  93
ASP A  57
 None
 0.67A 3v5wA-3ixlA:
undetectable		 3v5wA-3ixlA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1d 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME

(Mycobacterium
tuberculosis) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		3 LEU A 728
MET A 647
ASP A 635
 None
 0.88A 3v5wA-3k1dA:
undetectable		 3v5wA-3k1dA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyj CHEY6 PROTEIN

(Rhodobacter
sphaeroides) 		PF00072
(Response_reg) 		3 LEU B  52
MET B   6
ASP B   9
 None
 0.85A 3v5wA-3kyjB:
undetectable		 3v5wA-3kyjB:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m3g EPL1 PROTEIN

(Trichoderma
virens) 		PF07249
(Cerato-platanin) 		3 LEU A  84
MET A 110
ASP A  24
 None
 0.86A 3v5wA-3m3gA:
undetectable		 3v5wA-3m3gA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ml0 PENICILLIN G
ACYLASE, ALPHA
SUBUNIT

(Alcaligenes
faecalis) 		PF01804
(Penicil_amidase) 		3 LEU A  38
MET A  41
ASP A 134
 None
 0.75A 3v5wA-3ml0A:
undetectable		 3v5wA-3ml0A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ndo DEOXYRIBOSE-PHOSPHAT
E ALDOLASE

(Mycolicibacterium
smegmatis) 		PF01791
(DeoC) 		3 LEU A 187
MET A 179
ASP A 146
 None
None
GOL  A 229 (-2.8A)
 0.85A 3v5wA-3ndoA:
undetectable		 3v5wA-3ndoA:
14.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3nyo G PROTEIN-COUPLED
RECEPTOR KINASE 6

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		3 LEU A 263
MET A 266
ASP A 270
 AMP  A 577 ( 4.7A)
None
AMP  A 577 (-3.6A)
 0.56A 3v5wA-3nyoA:
12.4		 3v5wA-3nyoA:
34.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3onl T-SNARE VTI1

(Saccharomyces
cerevisiae) 		PF05008
(V-SNARE) 		3 LEU C   4
MET C  55
ASP C  50
 None
 0.63A 3v5wA-3onlC:
undetectable		 3v5wA-3onlC:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pdt MYOSIN HEAVY CHAIN
KINASE A

(Dictyostelium
discoideum) 		PF02816
(Alpha_kinase) 		3 LEU A 689
MET A 668
ASP A 663
 None
 0.89A 3v5wA-3pdtA:
4.7		 3v5wA-3pdtA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6w LACCASE

(Steccherinum
ochraceum) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 LEU A 156
MET A 160
ASP A 456
 None
 0.86A 3v5wA-3t6wA:
undetectable		 3v5wA-3t6wA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]

(Coxiella
burnetii) 		PF00117
(GATase)
PF00958
(GMP_synt_C)
PF02540
(NAD_synthase) 		3 LEU A 178
MET A 141
ASP A 138
 None
 0.87A 3v5wA-3tqiA:
undetectable		 3v5wA-3tqiA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v39 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE

(Bdellovibrio
bacteriovorus) 		PF02113
(Peptidase_S13) 		3 LEU A  78
MET A 310
ASP A 283
 None
 0.73A 3v5wA-3v39A:
undetectable		 3v5wA-3v39A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v39 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE

(Bdellovibrio
bacteriovorus) 		PF02113
(Peptidase_S13) 		3 LEU A 244
MET A 332
ASP A 327
 None
 0.92A 3v5wA-3v39A:
undetectable		 3v5wA-3v39A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wel ALPHA-GLUCOSIDASE

(Beta vulgaris) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16863
(NtCtMGAM_N) 		3 LEU A 897
MET A 843
ASP A 893
 None
 0.81A 3v5wA-3welA:
undetectable		 3v5wA-3welA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zbf PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ROS

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 LEU A2026
MET A2029
ASP A2033
 VGH  A3000 ( 4.2A)
None
VGH  A3000 (-4.5A)
 0.60A 3v5wA-3zbfA:
7.5		 3v5wA-3zbfA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhe NONSENSE-MEDIATED
MRNA DECAY PROTEIN

(Caenorhabditis
elegans) 		no annotation 3 LEU A  85
MET A 119
ASP A 114
 None
 0.75A 3v5wA-3zheA:
undetectable		 3v5wA-3zheA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zid TUBULIN/FTSZ, GTPASE

(Methanothrix
thermoacetophila) 		PF00091
(Tubulin) 		3 LEU A 320
MET A 225
ASP A 220
 None
 0.53A 3v5wA-3zidA:
undetectable		 3v5wA-3zidA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aie GLUCAN
1,6-ALPHA-GLUCOSIDAS
E

(Lactobacillus
acidophilus) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 LEU A  83
MET A  77
ASP A  71
 None
 0.66A 3v5wA-4aieA:
undetectable		 3v5wA-4aieA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b8a GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF16415
(CNOT1_CAF1_bind) 		3 LEU A 774
MET A 771
ASP A 881
 None
 0.84A 3v5wA-4b8aA:
undetectable		 3v5wA-4b8aA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b99 MITOGEN-ACTIVATED
PROTEIN KINASE 7

(Homo sapiens) 		PF00069
(Pkinase) 		3 LEU A 137
MET A 140
ASP A 143
 R4L  A1394 (-3.9A)
None
R4L  A1394 ( 4.2A)
 0.57A 3v5wA-4b99A:
25.7		 3v5wA-4b99A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c2x GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 2

(Homo sapiens) 		PF01233
(NMT)
PF02799
(NMT_C) 		3 LEU A 441
MET A 435
ASP A 396
 None
 0.86A 3v5wA-4c2xA:
undetectable		 3v5wA-4c2xA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cag POLYSACCHARIDE LYASE
FAMILY 11 PROTEIN

(Bacillus
licheniformis) 		PF01839
(FG-GAP) 		3 LEU A 335
MET A 353
ASP A 356
 None
None
CA  A 606 (-2.5A)
 0.78A 3v5wA-4cagA:
undetectable		 3v5wA-4cagA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dsh UDP-GALACTOPYRANOSE
MUTASE

(Trypanosoma
cruzi) 		PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8) 		3 LEU A 269
MET A 271
ASP A 240
 None
FDA  A 502 ( 4.9A)
None
 0.80A 3v5wA-4dshA:
undetectable		 3v5wA-4dshA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4s TUMOR NECROSIS
FACTOR LIGAND
SUPERFAMILY MEMBER
18

(Ochotona
princeps) 		no annotation 3 LEU A  27
MET A  30
ASP A  32
 None
 0.82A 3v5wA-4e4sA:
undetectable		 3v5wA-4e4sA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4epa PESTICIN RECEPTOR

(Yersinia pestis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 LEU A 538
MET A 484
ASP A  78
 None
 0.77A 3v5wA-4epaA:
undetectable		 3v5wA-4epaA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4es9 EPF

(Streptococcus
pyogenes) 		no annotation 3 LEU A 225
MET A 223
ASP A 186
 None
 0.73A 3v5wA-4es9A:
undetectable		 3v5wA-4es9A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fod ALK TYROSINE KINASE
RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 LEU A1196
MET A1199
ASP A1203
 0UV  A1501 (-3.7A)
None
0UV  A1501 ( 4.6A)
 0.40A 3v5wA-4fodA:
8.1		 3v5wA-4fodA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hl4 TBC1 DOMAIN FAMILY
MEMBER 20

(Homo sapiens) 		PF00566
(RabGAP-TBC) 		3 LEU A 266
MET A 207
ASP A 197
 None
 0.90A 3v5wA-4hl4A:
undetectable		 3v5wA-4hl4A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN

(Bacteroides
fragilis) 		PF00092
(VWA) 		3 LEU A 144
MET A  93
ASP A 129
 None
 0.80A 3v5wA-4jduA:
undetectable		 3v5wA-4jduA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k29 ENOYL-COA
HYDRATASE/ISOMERASE

(Xanthobacter
autotrophicus) 		PF00378
(ECH_1) 		3 LEU A 119
MET A  93
ASP A  88
 None
 0.83A 3v5wA-4k29A:
undetectable		 3v5wA-4k29A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lut ALANINE RACEMASE

(Clostridioides
difficile) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		3 LEU A 359
MET A 361
ASP A 289
 None
 0.90A 3v5wA-4lutA:
undetectable		 3v5wA-4lutA:
19.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4mk0 BETA-ADRENERGIC
RECEPTOR KINASE 1

(Homo sapiens) 		PF00069
(Pkinase)
PF00169
(PH)
PF00615
(RGS) 		3 LEU A 271
MET A 274
ASP A 278
 29X  A 702 ( 4.7A)
None
29X  A 702 ( 4.8A)
 0.23A 3v5wA-4mk0A:
56.2		 3v5wA-4mk0A:
97.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mrq PHOSPHOMANNOMUTASE/P
HOSPHOGLUCOMUTASE

(Pseudomonas
aeruginosa) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 LEU A 156
MET A  84
ASP A 244
 None
None
ZN  A 501 ( 2.5A)
 0.90A 3v5wA-4mrqA:
undetectable		 3v5wA-4mrqA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n3s EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5B

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2) 		3 LEU A 664
MET A 734
ASP A 728
 None
 0.67A 3v5wA-4n3sA:
undetectable		 3v5wA-4n3sA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pe3 TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT

(Rhodobacter
sphaeroides) 		PF03480
(DctP) 		3 LEU A 162
MET A 153
ASP A 121
 ACT  A 404 (-4.9A)
None
None
 0.88A 3v5wA-4pe3A:
undetectable		 3v5wA-4pe3A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pk1 CHIMERA PROTEIN OF
OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTORS BAMA AND
BAMB

(Escherichia
coli) 		PF07244
(POTRA)
PF13360
(PQQ_2) 		3 LEU A1323
MET A1032
ASP A 250
 None
 0.90A 3v5wA-4pk1A:
2.9		 3v5wA-4pk1A:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4tnb G PROTEIN-COUPLED
RECEPTOR KINASE 5

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		3 LEU A 263
MET A 266
ASP A 270
 SGV  A 601 (-4.5A)
None
SGV  A 601 (-4.2A)
 0.23A 3v5wA-4tnbA:
13.4		 3v5wA-4tnbA:
33.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN

(Salmonella
enterica) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl)
PF11974
(MG1) 		3 LEU A1357
MET A1336
ASP A1379
 None
 0.68A 3v5wA-4u48A:
undetectable		 3v5wA-4u48A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uoz BETA-GALACTOSIDASE

(Bifidobacterium
animalis) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		3 LEU A  45
MET A 378
ASP A 391
 None
 0.80A 3v5wA-4uozA:
undetectable		 3v5wA-4uozA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzs BETA-GALACTOSIDASE

(Bifidobacterium
bifidum) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		3 LEU A  42
MET A 374
ASP A 387
 None
 0.86A 3v5wA-4uzsA:
undetectable		 3v5wA-4uzsA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xky DIHYDRODIPICOLINATE
SYNTHASE

(Bacteroides
thetaiotaomicron) 		PF00701
(DHDPS) 		3 LEU A 135
MET A 188
ASP A 185
 None
 0.86A 3v5wA-4xkyA:
undetectable		 3v5wA-4xkyA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhg GH5

(Bacteroidetes
bacterium AC2a) 		PF00150
(Cellulase) 		3 LEU A 128
MET A  73
ASP A  33
 None
 0.90A 3v5wA-4yhgA:
undetectable		 3v5wA-4yhgA:
18.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4yhj G PROTEIN-COUPLED
RECEPTOR KINASE 4

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		3 LEU A 264
MET A 267
ASP A 271
 AN2  A 601 ( 4.8A)
None
None
 0.34A 3v5wA-4yhjA:
15.6		 3v5wA-4yhjA:
33.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zze SUGAR BINDING
PROTEIN OF ABC
TRANSPORTER SYSTEM

(Bifidobacterium
animalis) 		PF01547
(SBP_bac_1) 		3 LEU A 348
MET A 342
ASP A 104
 None
 0.92A 3v5wA-4zzeA:
undetectable		 3v5wA-4zzeA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dbk TRANSCRIPTIONAL
REGULATOR/TPR DOMAIN
PROTEIN

(Bacillus
thuringiensis) 		PF13424
(TPR_12) 		3 LEU A 106
MET A 102
ASP A  71
 None
 0.75A 3v5wA-5dbkA:
2.2		 3v5wA-5dbkA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e1t TNF
RECEPTOR-ASSOCIATED
FACTOR 1

(Homo sapiens) 		no annotation 3 LEU A 270
MET A 348
ASP A 351
 None
 0.92A 3v5wA-5e1tA:
undetectable		 3v5wA-5e1tA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h05 AMYP

(marine
metagenome) 		PF00128
(Alpha-amylase) 		3 LEU A 110
MET A 104
ASP A  98
 None
 0.85A 3v5wA-5h05A:
undetectable		 3v5wA-5h05A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdh TOLL-LIKE RECEPTOR 8

(Homo sapiens) 		PF13855
(LRR_8) 		3 LEU A 767
MET A 787
ASP A 782
 None
 0.75A 3v5wA-5hdhA:
undetectable		 3v5wA-5hdhA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hlb PENICILLIN-BINDING
PROTEIN 1B

(Escherichia
coli) 		PF00905
(Transpeptidase)
PF00912
(Transgly)
PF14814
(UB2H) 		3 LEU A 272
MET A 293
ASP A  88
 None
 0.88A 3v5wA-5hlbA:
undetectable		 3v5wA-5hlbA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hor HEPATOCYTE GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 LEU A1157
MET A1160
ASP A1164
 63K  A1401 (-4.2A)
None
63K  A1401 (-4.0A)
 0.50A 3v5wA-5horA:
7.2		 3v5wA-5horA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jnb POLY(A) RNA
POLYMERASE GLD-2

(Caenorhabditis
elegans) 		PF03828
(PAP_assoc) 		3 LEU A 781
MET A 546
ASP A 911
 None
 0.52A 3v5wA-5jnbA:
undetectable		 3v5wA-5jnbA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE

([Clostridium]
bolteae) 		PF00953
(Glycos_transf_4)
PF10555
(MraY_sig1) 		3 LEU A 137
MET A 248
ASP A 200
 None
 0.80A 3v5wA-5jnqA:
undetectable		 3v5wA-5jnqA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jta NEUTRAL TREHALASE

(Saccharomyces
cerevisiae) 		no annotation 3 LEU A 598
MET A 590
ASP A 549
 None
 0.81A 3v5wA-5jtaA:
undetectable		 3v5wA-5jtaA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m1b 3-OCTAPRENYL-4-HYDRO
XYBENZOATE
CARBOXY-LYASE

(Escherichia
coli) 		PF01977
(UbiD) 		3 LEU A 365
MET A 451
ASP A 454
 None
 0.80A 3v5wA-5m1bA:
undetectable		 3v5wA-5m1bA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nec TONB-DEPENDENT
SIDEROPHORE RECEPTOR

(Pseudomonas
aeruginosa) 		no annotation 3 LEU A 603
MET A 631
ASP A  99
 None
 0.63A 3v5wA-5necA:
undetectable		 3v5wA-5necA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE

(Rhizobium sp.
NT-26) 		no annotation 3 LEU A 538
MET A 509
ASP A 531
 None
 0.83A 3v5wA-5nqdA:
undetectable		 3v5wA-5nqdA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot4 INTERAPTIN

(Legionella
pneumophila) 		no annotation 3 LEU A 725
MET A 719
ASP A 712
 None
 0.90A 3v5wA-5ot4A:
2.1		 3v5wA-5ot4A:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5td2 TYROSINE-PROTEIN
KINASE MER

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 LEU A 671
MET A 674
ASP A 678
 7AE  A1000 (-3.7A)
None
7AE  A1000 ( 4.8A)
 0.63A 3v5wA-5td2A:
10.0		 3v5wA-5td2A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ti8 AMINOTRANSFERASE

(Pseudomonas sp.
M1) 		PF00202
(Aminotran_3) 		3 LEU A 130
MET A 132
ASP A 284
 None
 0.64A 3v5wA-5ti8A:
undetectable		 3v5wA-5ti8A:
21.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5uuu BETA-ADRENERGIC
RECEPTOR KINASE 1

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		3 LEU A 271
MET A 274
ASP A 278
 QRW  A 601 ( 4.9A)
MES  A 604 (-3.9A)
None
 0.19A 3v5wA-5uuuA:
54.6		 3v5wA-5uuuA:
95.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y9p -

(-) 		no annotation 3 LEU A 119
MET A 199
ASP A  78
 None
 0.55A 3v5wA-5y9pA:
undetectable		 3v5wA-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zvt CORE PROTEIN VP6

(Aquareovirus C) 		no annotation 3 LEU U 132
MET U 135
ASP U 141
 None
 0.86A 3v5wA-5zvtU:
undetectable		 3v5wA-5zvtU:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dll P-HYDROXYBENZOATE
HYDROXYLASE

(Pseudomonas
putida) 		no annotation 3 LEU A 139
MET A   1
ASP A  27
 None
 0.90A 3v5wA-6dllA:
undetectable		 3v5wA-6dllA:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 3 LEU A2511
MET A2513
ASP A2166
 None
 0.78A 3v5wA-6fb3A:
2.6		 3v5wA-6fb3A:
11.11