SIMILAR PATTERNS OF AMINO ACIDS FOR 3V4T_D_ACTD502_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)

(Escherichia
coli) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 GLY A 399
THR A 164
ASN A 404
 CER  A 413 (-3.2A)
None
None
 0.73A 3v4tD-1b3nA:
0.0		 3v4tD-1b3nA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)

(Thermococcus
litoralis) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		3 GLY A 101
THR A  90
ASN A  61
 None
 0.70A 3v4tD-1bvuA:
0.0		 3v4tD-1bvuA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE

(Escherichia
coli) 		PF00156
(Pribosyltran)
PF13522
(GATase_6) 		3 GLY A  65
THR A  35
ASN A  13
 None
 0.67A 3v4tD-1ecgA:
0.0		 3v4tD-1ecgA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j2z ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE

(Helicobacter
pylori) 		PF00132
(Hexapep)
PF13720
(Acetyltransf_11) 		3 GLY A  97
THR A 105
ASN A  95
 None
 0.66A 3v4tD-1j2zA:
0.0		 3v4tD-1j2zA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jjf ENDO-1,4-BETA-XYLANA
SE Z

(Ruminiclostridium
thermocellum) 		PF00756
(Esterase) 		3 GLY A 182
THR A 184
ASN A 180
 None
 0.64A 3v4tD-1jjfA:
undetectable		 3v4tD-1jjfA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kj0 SERINE PROTEASE
INHIBITOR I

(Schistocerca
gregaria) 		PF05375
(Pacifastin_I) 		3 GLY A   7
THR A  20
ASN A  18
 None
 0.65A 3v4tD-1kj0A:
undetectable		 3v4tD-1kj0A:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA

(Bacillus
subtilis) 		PF01522
(Polysacc_deac_1) 		3 GLY A 216
THR A  67
ASN A  62
 None
 0.62A 3v4tD-1ny1A:
0.0		 3v4tD-1ny1A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgp 6-PHOSPHOGLUCONATE
DEHYDROGENASE

(Ovis aries) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		3 GLY A 263
THR A 266
ASN A 187
 None
None
6PG  A 502 (-2.9A)
 0.71A 3v4tD-1pgpA:
0.0		 3v4tD-1pgpA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pue PROTEIN
(TRANSCRIPTION
FACTOR PU.1 (TF
PU.1))

(Mus musculus) 		PF00178
(Ets) 		3 GLY E 238
THR E 240
ASN E 236
 None
 0.65A 3v4tD-1pueE:
undetectable		 3v4tD-1pueE:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qf6 THREONYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF00587
(tRNA-synt_2b)
PF02824
(TGS)
PF03129
(HGTP_anticodon)
PF07973
(tRNA_SAD) 		3 GLY A 101
THR A 221
ASN A 100
 None
 0.68A 3v4tD-1qf6A:
0.0		 3v4tD-1qf6A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qwy PEPTIDOGLYCAN
HYDROLASE

(Staphylococcus
aureus) 		PF01551
(Peptidase_M23) 		3 GLY A 242
THR A 284
ASN A 261
 None
 0.70A 3v4tD-1qwyA:
undetectable		 3v4tD-1qwyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rz6 CYTOCHROME C
PEROXIDASE

(Marinobacter
hydrocarbonoclasticus) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		3 GLY A  60
THR A 256
ASN A 252
 None
 0.71A 3v4tD-1rz6A:
undetectable		 3v4tD-1rz6A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sg1 TUMOR NECROSIS
FACTOR RECEPTOR
SUPERFAMILY MEMBER
16

(Rattus
norvegicus) 		PF00020
(TNFR_c6) 		3 GLY X  30
THR X  10
ASN X  32
 None
 0.69A 3v4tD-1sg1X:
undetectable		 3v4tD-1sg1X:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t44 CHIMERA OF GELSOLIN
DOMAIN 1 AND
C-TERMINAL DOMAIN OF
THYMOSIN BETA-4

(Homo sapiens;
Mus musculus) 		PF00626
(Gelsolin)
PF01290
(Thymosin) 		3 GLY G  90
THR G  64
ASN G  91
 None
 0.66A 3v4tD-1t44G:
undetectable		 3v4tD-1t44G:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1td6 HYPOTHETICAL PROTEIN
MG237 HOMOLOG

(Mycoplasma
pneumoniae) 		PF11428
(DUF3196) 		3 GLY A  37
THR A  41
ASN A  36
 None
 0.73A 3v4tD-1td6A:
undetectable		 3v4tD-1td6A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tke THREONYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF02824
(TGS)
PF07973
(tRNA_SAD) 		3 GLY A 101
THR A 221
ASN A 100
 None
 0.66A 3v4tD-1tkeA:
undetectable		 3v4tD-1tkeA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqy ACTINORHODIN
POLYKETIDE PUTATIVE
BETA-KETOACYL
SYNTHASE 2

(Streptomyces
coelicolor) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 GLY B 186
THR B 102
ASN B 140
 None
 0.65A 3v4tD-1tqyB:
undetectable		 3v4tD-1tqyB:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wd3 ALPHA-L-ARABINOFURAN
OSIDASE B

(Aspergillus
kawachii) 		PF05270
(AbfB)
PF09206
(ArabFuran-catal) 		3 GLY A 395
THR A 437
ASN A 398
 None
 0.61A 3v4tD-1wd3A:
undetectable		 3v4tD-1wd3A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wqa PHOSPHO-SUGAR MUTASE

(Pyrococcus
horikoshii) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 GLY A 210
THR A  50
ASN A 183
 GLY  A 210 ( 0.0A)
THR  A  50 ( 0.8A)
ASN  A 183 ( 0.6A)
 0.62A 3v4tD-1wqaA:
undetectable		 3v4tD-1wqaA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zov MONOMERIC SARCOSINE
OXIDASE

(Bacillus sp.
NS-129) 		PF01266
(DAO) 		3 GLY A 341
THR A 318
ASN A 205
 None
 0.45A 3v4tD-1zovA:
undetectable		 3v4tD-1zovA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c5q RRAA-LIKE PROTEIN
YER010C

(Saccharomyces
cerevisiae) 		PF03737
(RraA-like) 		3 GLY A  47
THR A  48
ASN A  73
 None
 0.70A 3v4tD-2c5qA:
undetectable		 3v4tD-2c5qA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cb5 PROTEIN (BLEOMYCIN
HYDROLASE)

(Homo sapiens) 		PF03051
(Peptidase_C1_2) 		3 GLY A  31
THR A  33
ASN A  29
 None
 0.71A 3v4tD-2cb5A:
undetectable		 3v4tD-2cb5A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e0p ENDOGLUCANASE

(Ruminiclostridium
thermocellum) 		PF12891
(Glyco_hydro_44) 		3 GLY A  44
THR A 108
ASN A 185
 GOL  A 601 (-3.9A)
None
CTT  A 800 (-3.2A)
 0.72A 3v4tD-2e0pA:
0.3		 3v4tD-2e0pA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ff6 GELSOLIN

(Homo sapiens) 		PF00626
(Gelsolin) 		3 GLY G  90
THR G  64
ASN G  91
 None
 0.67A 3v4tD-2ff6G:
undetectable		 3v4tD-2ff6G:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		3 GLY A 366
THR A 369
ASN A 360
 FAD  A 611 (-3.3A)
None
None
 0.68A 3v4tD-2gmhA:
undetectable		 3v4tD-2gmhA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inr DNA TOPOISOMERASE 4
SUBUNIT A

(Staphylococcus
aureus) 		PF00521
(DNA_topoisoIV) 		3 GLY A 104
THR A 120
ASN A 106
 None
 0.69A 3v4tD-2inrA:
undetectable		 3v4tD-2inrA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iou MAJOR TROPISM
DETERMINANT P1

(Bordetella
virus BPP1) 		no annotation 3 GLY A 155
THR A 294
ASN A 291
 None
 0.66A 3v4tD-2iouA:
undetectable		 3v4tD-2iouA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iwz 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE

(Homo sapiens) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 GLY A 446
THR A 210
ASN A 451
 6NA  A1460 (-3.3A)
None
None
 0.73A 3v4tD-2iwzA:
undetectable		 3v4tD-2iwzA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jpo PHEROMONE-BINDING
PROTEIN

(Antheraea
polyphemus) 		PF01395
(PBP_GOBP) 		3 GLY A  49
THR A 111
ASN A  53
 None
 0.67A 3v4tD-2jpoA:
undetectable		 3v4tD-2jpoA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m0g SPLICING FACTOR 1
SPLICING FACTOR U2AF
65 KDA SUBUNIT

(Homo sapiens;
Homo sapiens) 		PF16275
(SF1-HH)
PF00076
(RRM_1) 		3 GLY A  71
THR A  26
ASN B 456
 None
 0.67A 3v4tD-2m0gA:
undetectable		 3v4tD-2m0gA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mdk VESICLE-ASSOCIATED
MEMBRANE
PROTEIN-ASSOCIATED
PROTEIN B/C

(Homo sapiens) 		PF00635
(Motile_Sperm) 		3 GLY A  59
THR A  36
ASN A  39
 None
 0.66A 3v4tD-2mdkA:
undetectable		 3v4tD-2mdkA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4q 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING 1

(Saccharomyces
cerevisiae) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		3 GLY A 262
THR A 265
ASN A 186
 None
None
FLC  A 502 (-2.6A)
 0.68A 3v4tD-2p4qA:
1.3		 3v4tD-2p4qA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qm1 GLUCOKINASE

(Enterococcus
faecalis) 		PF00480
(ROK) 		3 GLY A 255
THR A 257
ASN A 253
 None
 0.70A 3v4tD-2qm1A:
undetectable		 3v4tD-2qm1A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqu BETA-FRUCTOFURANOSID
ASE

(Arabidopsis
thaliana) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		3 GLY A 214
THR A 211
ASN A 216
 None
 0.72A 3v4tD-2qquA:
undetectable		 3v4tD-2qquA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v26 MYOSIN VI

(Sus scrofa) 		PF00063
(Myosin_head) 		3 GLY A 277
THR A 279
ASN A 275
 None
 0.65A 3v4tD-2v26A:
undetectable		 3v4tD-2v26A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vul GH11 XYLANASE

(Escherichia
coli) 		PF00457
(Glyco_hydro_11) 		3 GLY A  97
THR A  71
ASN A  74
 None
 0.68A 3v4tD-2vulA:
undetectable		 3v4tD-2vulA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vwb PUTATIVE
O-SIALOGLYCOPROTEIN
ENDOPEPTIDASE

(Methanocaldococcus
jannaschii) 		PF00814
(Peptidase_M22)
PF01163
(RIO1) 		3 GLY A  14
THR A  29
ASN A 285
 None
 0.69A 3v4tD-2vwbA:
undetectable		 3v4tD-2vwbA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5f ENDO-1,4-BETA-XYLANA
SE Y

(Ruminiclostridium
thermocellum) 		PF00331
(Glyco_hydro_10)
PF02018
(CBM_4_9) 		3 GLY A  64
THR A  68
ASN A  65
 None
CD  A1559 (-3.5A)
None
 0.62A 3v4tD-2w5fA:
1.1		 3v4tD-2w5fA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z2m PENICILLIN-BINDING
PROTEIN 2X

(Streptococcus
pneumoniae) 		PF00905
(Transpeptidase) 		3 GLY B 399
THR B 401
ASN B 397
 None
None
CDS  B 901 ( 3.0A)
 0.70A 3v4tD-2z2mB:
undetectable		 3v4tD-2z2mB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zy2 L-ASPARTATE
4-CARBOXYLYASE

(Pseudomonas sp.
ATCC 19121) 		PF00155
(Aminotran_1_2) 		3 GLY A 131
THR A 387
ASN A 133
 None
 0.69A 3v4tD-2zy2A:
undetectable		 3v4tD-2zy2A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3auo DNA POLYMERASE BETA
FAMILY (X FAMILY)

(Thermus
thermophilus) 		PF14520
(HHH_5)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb) 		3 GLY A 350
THR A 346
ASN A 352
 None
 0.63A 3v4tD-3auoA:
undetectable		 3v4tD-3auoA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c37 PEPTIDASE, M48
FAMILY

(Geobacter
sulfurreducens) 		PF01435
(Peptidase_M48) 		3 GLY A 182
THR A  98
ASN A 179
 None
 0.53A 3v4tD-3c37A:
undetectable		 3v4tD-3c37A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvg PUTATIVE METAL
BINDING PROTEIN

(Coccidioides
immitis) 		PF12849
(PBP_like_2) 		3 GLY A  96
THR A  84
ASN A  44
 None
 0.69A 3v4tD-3cvgA:
undetectable		 3v4tD-3cvgA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fk2 GLUCOCORTICOID
RECEPTOR DNA-BINDING
FACTOR 1

(Homo sapiens) 		PF00620
(RhoGAP) 		3 GLY A1287
THR A1316
ASN A1288
 None
 0.54A 3v4tD-3fk2A:
undetectable		 3v4tD-3fk2A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fnk CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B

(Acetivibrio
cellulolyticus) 		PF00963
(Cohesin) 		3 GLY A 146
THR A 151
ASN A 145
 None
 0.71A 3v4tD-3fnkA:
undetectable		 3v4tD-3fnkA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i7j BETA-LACTAMASE
MB2281C

(Mycobacterium
bovis) 		PF00144
(Beta-lactamase) 		3 GLY A 103
THR A 105
ASN A 101
 None
 0.71A 3v4tD-3i7jA:
undetectable		 3v4tD-3i7jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ik2 ENDOGLUCANASE A

(Clostridium
acetobutylicum) 		PF12891
(Glyco_hydro_44) 		3 GLY A  38
THR A 102
ASN A 179
 None
 0.72A 3v4tD-3ik2A:
0.2		 3v4tD-3ik2A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k92 NAD-SPECIFIC
GLUTAMATE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		3 GLY A 113
THR A 102
ASN A  73
 None
 0.51A 3v4tD-3k92A:
undetectable		 3v4tD-3k92A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kmv ALPHA-L-ARABINOFURAN
OSIDASE B

(Ruminiclostridium
thermocellum) 		PF05270
(AbfB) 		3 GLY A  49
THR A  93
ASN A  52
 None
 0.64A 3v4tD-3kmvA:
undetectable		 3v4tD-3kmvA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l9y SUPEROXIDE DISMUTASE
[CU-ZN]

(Bombyx mori) 		PF00080
(Sod_Cu) 		3 GLY A  50
THR A 116
ASN A  52
 None
 0.71A 3v4tD-3l9yA:
undetectable		 3v4tD-3l9yA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m0o MONOMERIC SARCOSINE
OXIDASE

(Bacillus sp.
B-0618) 		PF01266
(DAO) 		3 GLY A 341
THR A 318
ASN A 205
 None
 0.40A 3v4tD-3m0oA:
undetectable		 3v4tD-3m0oA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3naf CALCIUM-ACTIVATED
POTASSIUM CHANNEL
SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1

(Homo sapiens) 		PF03493
(BK_channel_a) 		3 GLY A 531
THR A1035
ASN A 509
 None
 0.68A 3v4tD-3nafA:
2.7		 3v4tD-3nafA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o5c CYTOCHROME C551
PEROXIDASE

(Shewanella
oneidensis) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		3 GLY A  69
THR A 260
ASN A 256
 None
 0.69A 3v4tD-3o5cA:
undetectable		 3v4tD-3o5cA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pgb PUTATIVE
UNCHARACTERIZED
PROTEIN

(Aspergillus
nidulans) 		PF01179
(Cu_amine_oxid)
PF09248
(DUF1965) 		3 GLY A 715
THR A 644
ASN A 713
 None
 0.71A 3v4tD-3pgbA:
undetectable		 3v4tD-3pgbA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pkj NAD-DEPENDENT
DEACETYLASE
SIRTUIN-6

(Homo sapiens) 		PF02146
(SIR2) 		3 GLY A 132
THR A 182
ASN A 133
 None
 0.64A 3v4tD-3pkjA:
undetectable		 3v4tD-3pkjA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qsl PUTATIVE EXPORTED
PROTEIN

(Bordetella
bronchiseptica) 		PF13379
(NMT1_2) 		3 GLY A 305
THR A 308
ASN A 226
 None
 0.53A 3v4tD-3qslA:
undetectable		 3v4tD-3qslA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rfr PMOA

(Methylocystis
sp. M) 		no annotation 3 GLY J 115
THR J 117
ASN J 112
 None
 0.71A 3v4tD-3rfrJ:
undetectable		 3v4tD-3rfrJ:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ro2 G-PROTEIN-SIGNALING
MODULATOR 2

(Mus musculus) 		PF13176
(TPR_7)
PF13424
(TPR_12) 		3 GLY A 102
THR A 104
ASN A 100
 None
None
GOL  A   2 (-3.6A)
 0.72A 3v4tD-3ro2A:
0.2		 3v4tD-3ro2A:
22.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3swd UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Escherichia
coli) 		PF00275
(EPSP_synthase) 		3 GLY A   8
THR A  10
ASN A 412
 None
 0.17A 3v4tD-3swdA:
69.2		 3v4tD-3swdA:
93.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u6n HIGH-CONDUCTANCE
CA2+-ACTIVATED K+
CHANNEL PROTEIN

(Danio rerio) 		PF02254
(TrkA_N)
PF03493
(BK_channel_a) 		3 GLY A 531
THR A1039
ASN A 509
 None
 0.56A 3v4tD-3u6nA:
2.0		 3v4tD-3u6nA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zg6 NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-6

(Homo sapiens) 		PF02146
(SIR2) 		3 GLY A 132
THR A 182
ASN A 133
 None
 0.69A 3v4tD-3zg6A:
undetectable		 3v4tD-3zg6A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zrp SERINE-PYRUVATE
AMINOTRANSFERASE
(AGXT)

(Sulfolobus
solfataricus) 		PF00266
(Aminotran_5) 		3 GLY A 111
THR A 140
ASN A  85
 None
 0.69A 3v4tD-3zrpA:
undetectable		 3v4tD-3zrpA:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zuy TRANSPORTER

(Neisseria
meningitidis) 		PF01758
(SBF) 		3 GLY A 123
THR A 256
ASN A 124
 None
 0.71A 3v4tD-3zuyA:
undetectable		 3v4tD-3zuyA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria;
Sus scrofa) 		PF00063
(Myosin_head)
PF01353
(GFP) 		3 GLY A 277
THR A 279
ASN A 275
 None
 0.66A 3v4tD-4anjA:
undetectable		 3v4tD-4anjA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d70 SORTASE FAMILY
PROTEIN

(Clostridium
perfringens) 		PF04203
(Sortase) 		3 GLY A 102
THR A 165
ASN A 160
 None
 0.70A 3v4tD-4d70A:
undetectable		 3v4tD-4d70A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3h TOPOISOMERASE IV
SUBUNIT B, DNA
TOPOISOMERASE 4
SUBUNIT A CHIMERA

(Streptococcus
pneumoniae) 		PF00204
(DNA_gyraseB)
PF00521
(DNA_topoisoIV)
PF00986
(DNA_gyraseB_C)
PF01751
(Toprim)
PF02518
(HATPase_c) 		3 GLY A1103
THR A1119
ASN A1105
 None
 0.65A 3v4tD-4i3hA:
undetectable		 3v4tD-4i3hA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m47 DNA POLYMERASE BETA

(Homo sapiens) 		PF10391
(DNA_pol_lambd_f)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		3 GLY A  14
THR A  16
ASN A  12
 None
 0.67A 3v4tD-4m47A:
undetectable		 3v4tD-4m47A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pkh GELSOLIN,TROPOMODULI
N-1 CHIMERA

(Homo sapiens) 		PF00626
(Gelsolin)
PF03250
(Tropomodulin) 		3 GLY B 117
THR B  91
ASN B 118
 None
 0.67A 3v4tD-4pkhB:
undetectable		 3v4tD-4pkhB:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pki GELSOLIN,TROPOMODULI
N-1 CHIMERA

(Homo sapiens) 		PF00626
(Gelsolin) 		3 GLY G 117
THR G  91
ASN G 118
 None
 0.70A 3v4tD-4pkiG:
1.3		 3v4tD-4pkiG:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r37 PUTATIVE
ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE

(Bacteroides
fragilis) 		PF00132
(Hexapep)
PF13720
(Acetyltransf_11) 		3 GLY A  95
THR A 102
ASN A  93
 None
None
ACT  A1004 ( 4.8A)
 0.63A 3v4tD-4r37A:
undetectable		 3v4tD-4r37A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tsh SURFACE PROTEIN
ADHESIN

(Streptococcus
mutans) 		PF16364
(Antigen_C) 		3 GLY B1116
THR B1142
ASN B1114
 None
 0.63A 3v4tD-4tshB:
undetectable		 3v4tD-4tshB:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xev FUSION PROTEIN OF
PROTEIN-TYROSINE
KINASE 2-BETA FAT
DOMAIN AND LEUPAXIN
LD1 MOTIF

(Homo sapiens) 		PF03623
(Focal_AT) 		3 GLY A 914
THR A 916
ASN A 912
 None
 0.67A 3v4tD-4xevA:
undetectable		 3v4tD-4xevA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zfm PUTATIVE
6-PHOSPHO-BETA-GALAC
TOBIOSIDASE

(Geobacillus
stearothermophilus) 		PF00232
(Glyco_hydro_1) 		3 GLY A  51
THR A  48
ASN A  53
 None
 0.69A 3v4tD-4zfmA:
undetectable		 3v4tD-4zfmA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zkt BONTOXILYSIN A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		3 GLY A1210
THR A1223
ASN A1208
 None
 0.53A 3v4tD-4zktA:
undetectable		 3v4tD-4zktA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a01 O-GLYCOSYLTRANSFERAS
E

(Drosophila
melanogaster) 		PF13374
(TPR_10)
PF13414
(TPR_11)
PF13844
(Glyco_transf_41) 		3 GLY A 431
THR A 433
ASN A 429
 None
 0.66A 3v4tD-5a01A:
2.2		 3v4tD-5a01A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6c G-PROTEIN-SIGNALING
MODULATOR 2, AFADIN

(Homo sapiens) 		PF13176
(TPR_7)
PF13181
(TPR_8)
PF13424
(TPR_12) 		3 GLY A 102
THR A 104
ASN A 100
 None
 0.70A 3v4tD-5a6cA:
undetectable		 3v4tD-5a6cA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7d PINS

(Drosophila
melanogaster) 		PF13176
(TPR_7)
PF13424
(TPR_12) 		3 GLY B 225
THR B 227
ASN B 223
 None
 0.70A 3v4tD-5a7dB:
undetectable		 3v4tD-5a7dB:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aul PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT ALPHA

(Homo sapiens) 		PF00017
(SH2) 		3 GLY A 678
THR A 677
ASN A 686
 None
GOL  A 801 (-3.2A)
GOL  A 801 (-4.3A)
 0.69A 3v4tD-5aulA:
undetectable		 3v4tD-5aulA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dn2 NEUROPILIN-2

(Homo sapiens) 		PF00754
(F5_F8_type_C) 		3 GLY A 426
THR A 340
ASN A 278
 None
 0.73A 3v4tD-5dn2A:
undetectable		 3v4tD-5dn2A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fj8 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC7

(Saccharomyces
cerevisiae) 		PF11705
(RNA_pol_3_Rpc31) 		3 GLY Q  62
THR Q  64
ASN Q  60
 None
 0.66A 3v4tD-5fj8Q:
undetectable		 3v4tD-5fj8Q:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fja DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC7

(Saccharomyces
cerevisiae) 		PF11705
(RNA_pol_3_Rpc31) 		3 GLY Q  62
THR Q  64
ASN Q  60
 None
 0.68A 3v4tD-5fjaQ:
undetectable		 3v4tD-5fjaQ:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT ALPHA
T-COMPLEX PROTEIN 1
SUBUNIT DELTA

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00118
(Cpn60_TCP1)
PF00118
(Cpn60_TCP1) 		3 GLY d 459
THR a 123
ASN d 457
 None
 0.69A 3v4tD-5gw5d:
undetectable		 3v4tD-5gw5d:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT BETA
T-COMPLEX PROTEIN 1
SUBUNIT DELTA

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00118
(Cpn60_TCP1)
PF00118
(Cpn60_TCP1) 		3 GLY b 449
THR d 118
ASN b 447
 None
 0.67A 3v4tD-5gw5b:
undetectable		 3v4tD-5gw5b:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE

(Pseudomonas
aeruginosa) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		3 GLY A 299
THR A 302
ASN A 777
 None
 0.61A 3v4tD-5im3A:
1.4		 3v4tD-5im3A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5irc RHO
GTPASE-ACTIVATING
PROTEIN 35

(Rattus
norvegicus) 		PF00620
(RhoGAP) 		3 GLY A1287
THR A1316
ASN A1288
 None
 0.70A 3v4tD-5ircA:
undetectable		 3v4tD-5ircA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jmv PROBABLE
BIFUNCTIONAL TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN

(Methanocaldococcus
jannaschii) 		PF00814
(Peptidase_M22) 		3 GLY A  14
THR A  29
ASN A 285
 None
 0.69A 3v4tD-5jmvA:
undetectable		 3v4tD-5jmvA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwb TYPE II
NADH:UBIQUINONE
OXIDOREDUCTASE

(Plasmodium
falciparum) 		PF07992
(Pyr_redox_2) 		3 GLY A 246
THR A 274
ASN A 248
 None
 0.72A 3v4tD-5jwbA:
undetectable		 3v4tD-5jwbA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m5x DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA135

(Saccharomyces
cerevisiae) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF06883
(RNA_pol_Rpa2_4) 		3 GLY B 727
THR B 725
ASN B 767
 None
 0.70A 3v4tD-5m5xB:
undetectable		 3v4tD-5m5xB:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mb4 GLCNAC SPECIFIC
LECTIN

(Psathyrella) 		PF13517
(VCBS) 		3 GLY A 356
THR A 382
ASN A 358
 NAG  A 513 (-3.4A)
None
None
 0.72A 3v4tD-5mb4A:
undetectable		 3v4tD-5mb4A:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mn5 CELL DIVISION
PROTEIN FTSZ

(Staphylococcus
aureus) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		3 GLY A 266
THR A 265
ASN A 299
 None
 0.72A 3v4tD-5mn5A:
undetectable		 3v4tD-5mn5A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron) 		PF17132
(Glyco_hydro_106) 		3 GLY A 607
THR A1031
ASN A 913
 None
 0.73A 3v4tD-5mqmA:
1.2		 3v4tD-5mqmA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ngy DSR-M GLUCANSUCRASE
INACTIVE MUTANT
E715Q

(Leuconostoc
citreum) 		no annotation 3 GLY A 562
THR A 564
ASN A 560
 None
 0.71A 3v4tD-5ngyA:
undetectable		 3v4tD-5ngyA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB

(Escherichia
coli) 		PF00005
(ABC_tran)
PF02687
(FtsX)
PF12704
(MacB_PCD) 		3 GLY J 374
THR J 389
ASN J 378
 None
 0.72A 3v4tD-5nilJ:
0.9		 3v4tD-5nilJ:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5osg RNA BINDING PROTEIN,
PUTATIVE

(Leishmania
donovani) 		no annotation 3 GLY h 192
THR h 199
ASN h 191
 None
 0.64A 3v4tD-5osgh:
undetectable		 3v4tD-5osgh:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tj6 HIGH CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL

(Aplysia
californica) 		PF00520
(Ion_trans)
PF03493
(BK_channel_a) 		3 GLY A 521
THR A1045
ASN A 498
 None
 0.61A 3v4tD-5tj6A:
undetectable		 3v4tD-5tj6A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		no annotation 3 GLY A  28
THR A  98
ASN A  27
 None
 0.60A 3v4tD-5ua0A:
undetectable		 3v4tD-5ua0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xvn CRISPR-ASSOCIATED
ENDONUCLEASE CAS1

(Enterococcus
faecalis) 		PF01867
(Cas_Cas1) 		3 GLY A 179
THR A 181
ASN A 177
 None
 0.72A 3v4tD-5xvnA:
undetectable		 3v4tD-5xvnA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zu5 ALGINATE LYASE

(Vibrio
splendidus) 		no annotation 3 GLY A 268
THR A 264
ASN A 219
 None
 0.70A 3v4tD-5zu5A:
undetectable		 3v4tD-5zu5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eu2 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC7

(Saccharomyces
cerevisiae) 		no annotation 3 GLY Q  62
THR Q  64
ASN Q  60
 None
 0.67A 3v4tD-6eu2Q:
undetectable		 3v4tD-6eu2Q:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fhv GLUCOAMYLASE

(Penicillium
oxalicum) 		no annotation 3 GLY A 217
THR A 273
ASN A 270
 None
 0.61A 3v4tD-6fhvA:
undetectable		 3v4tD-6fhvA:
undetectable