SIMILAR PATTERNS OF AMINO ACIDS FOR 3V4T_C_ACTC503

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4egw MAGNESIUM TRANSPORT
PROTEIN CORA

(Methanocaldococcus
jannaschii) 		PF01544
(CorA) 		4 LYS A 110
PRO A  81
ILE A 150
ARG A 114
 None
 1.33A 3v4tC-4egwA:
0.0
3v4tD-4egwA:
0.6		 3v4tC-4egwA:
23.47
3v4tD-4egwA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cux ACIDOCALCISOMAL
PYROPHOSPHATASE

(Trypanosoma
cruzi) 		PF00719
(Pyrophosphatase) 		4 LYS A 250
PRO A 258
ILE A 253
ARG A 182
 None
 1.49A 3v4tC-5cuxA:
0.0
3v4tD-5cuxA:
0.0		 3v4tC-5cuxA:
21.20
3v4tD-5cuxA:
21.20