SIMILAR PATTERNS OF AMINO ACIDS FOR 3V4T_A_ACTA504_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a6g | MYOGLOBIN (Physetercatodon) |
PF00042(Globin) | 3 | THR A 70VAL A 66GLU A 18 | None | 0.71A | 3v4tA-1a6gA:undetectable3v4tD-1a6gA:undetectable | 3v4tA-1a6gA:17.943v4tD-1a6gA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1by7 | PROTEIN (PLASMINOGENACTIVATORINHIBITOR-2) (Homo sapiens) |
PF00079(Serpin) | 3 | THR A 194VAL A 197GLU A 132 | None | 0.75A | 3v4tA-1by7A:0.03v4tD-1by7A:undetectable | 3v4tA-1by7A:21.853v4tD-1by7A:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2f | MALY PROTEIN (Escherichiacoli) |
PF00155(Aminotran_1_2) | 3 | THR A 275VAL A 271GLU A 68 | None | 0.67A | 3v4tA-1d2fA:0.03v4tD-1d2fA:0.3 | 3v4tA-1d2fA:22.863v4tD-1d2fA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ezv | UBIQUINOL-CYTOCHROMEC REDUCTASE COMPLEXCORE PROTEIN I (Saccharomycescerevisiae) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 3 | THR A 210VAL A 208GLU A 41 | None | 0.77A | 3v4tA-1ezvA:0.03v4tD-1ezvA:0.0 | 3v4tA-1ezvA:22.953v4tD-1ezvA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8r | L-AMINO ACID OXIDASE (Calloselasmarhodostoma) |
PF01593(Amino_oxidase) | 3 | THR A 431VAL A 319GLU A 219 | None | 0.63A | 3v4tA-1f8rA:0.03v4tD-1f8rA:0.0 | 3v4tA-1f8rA:21.893v4tD-1f8rA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h0h | FORMATEDEHYDROGENASESUBUNIT ALPHA (Desulfovibriogigas) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 3 | THR A 30VAL A 28GLU A 65 | None | 0.75A | 3v4tA-1h0hA:0.03v4tD-1h0hA:0.0 | 3v4tA-1h0hA:18.363v4tD-1h0hA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k6d | ACETATECOA-TRANSFERASEALPHA SUBUNIT (Escherichiacoli) |
PF01144(CoA_trans) | 3 | THR A 31VAL A 23GLU A 188 | None | 0.47A | 3v4tA-1k6dA:0.03v4tD-1k6dA:0.0 | 3v4tA-1k6dA:22.513v4tD-1k6dA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mpo | MALTOPORIN (Escherichiacoli) |
PF02264(LamB) | 3 | THR A 216VAL A 231GLU A 188 | None | 0.70A | 3v4tA-1mpoA:0.03v4tD-1mpoA:0.0 | 3v4tA-1mpoA:23.113v4tD-1mpoA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n5x | XANTHINEDEHYDROGENASE (Bos taurus) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 3 | THR A 321VAL A 316GLU A 325 | None | 0.74A | 3v4tA-1n5xA:0.03v4tD-1n5xA:0.0 | 3v4tA-1n5xA:16.373v4tD-1n5xA:16.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pz3 | ALPHA-L-ARABINOFURANOSIDASE (Geobacillusstearothermophilus) |
PF06964(Alpha-L-AF_C) | 3 | THR A 422VAL A 413GLU A 420 | None | 0.63A | 3v4tA-1pz3A:undetectable3v4tD-1pz3A:0.0 | 3v4tA-1pz3A:21.633v4tD-1pz3A:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qni | NITROUS-OXIDEREDUCTASE (Marinobacterhydrocarbonoclasticus) |
no annotation | 3 | THR A 138VAL A 141GLU A 173 | None | 0.52A | 3v4tA-1qniA:undetectable3v4tD-1qniA:undetectable | 3v4tA-1qniA:22.173v4tD-1qniA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sjp | 60 KDA CHAPERONIN 2 (Mycobacteriumtuberculosis) |
PF00118(Cpn60_TCP1) | 3 | THR A 187VAL A 373GLU A 185 | None | 0.72A | 3v4tA-1sjpA:undetectable3v4tD-1sjpA:undetectable | 3v4tA-1sjpA:24.243v4tD-1sjpA:24.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdk | L-AMINO ACID OXIDASE (Gloydius halys) |
PF01593(Amino_oxidase) | 3 | THR A 431VAL A 319GLU A 219 | None | 0.68A | 3v4tA-1tdkA:undetectable3v4tD-1tdkA:undetectable | 3v4tA-1tdkA:22.103v4tD-1tdkA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tow | FATTY ACID-BINDINGPROTEIN, ADIPOCYTE (Homo sapiens) |
PF00061(Lipocalin) | 3 | THR A 103VAL A 92GLU A 116 | None | 0.72A | 3v4tA-1towA:undetectable3v4tD-1towA:undetectable | 3v4tA-1towA:18.383v4tD-1towA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u4q | SPECTRIN ALPHACHAIN, BRAIN (Gallus gallus) |
PF00435(Spectrin) | 3 | THR A1953VAL A1949GLU A1939 | None | 0.66A | 3v4tA-1u4qA:undetectable3v4tD-1u4qA:undetectable | 3v4tA-1u4qA:24.943v4tD-1u4qA:24.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xwi | SKD1 PROTEIN (Homo sapiens) |
PF00004(AAA)PF09336(Vps4_C) | 3 | THR A 256VAL A 260GLU A 213 | None | 0.73A | 3v4tA-1xwiA:1.03v4tD-1xwiA:1.1 | 3v4tA-1xwiA:24.333v4tD-1xwiA:24.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a8i | THREONINE ASPARTASE1 (Homo sapiens) |
PF01112(Asparaginase_2) | 3 | THR A 286VAL A 288GLU A 276 | None | 0.71A | 3v4tA-2a8iA:undetectable3v4tD-2a8iA:undetectable | 3v4tA-2a8iA:24.543v4tD-2a8iA:24.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ado | MEDIATOR OF DNADAMAGE CHECKPOINTPROTEIN 1 (Homo sapiens) |
PF16770(RTT107_BRCT_5) | 3 | THR A1971VAL A1969GLU A1976 | None | 0.69A | 3v4tA-2adoA:undetectable3v4tD-2adoA:undetectable | 3v4tA-2adoA:18.423v4tD-2adoA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ce9 | TRANSDUCIN-LIKEENHANCER PROTEIN 1 (Homo sapiens) |
PF00400(WD40) | 3 | THR A 716VAL A 714GLU A 738 | None | 0.57A | 3v4tA-2ce9A:undetectable3v4tD-2ce9A:undetectable | 3v4tA-2ce9A:21.603v4tD-2ce9A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2clb | DPS-LIKE PROTEIN (Sulfolobussolfataricus) |
PF00210(Ferritin) | 3 | THR A 130VAL A 134GLU A 156 | NoneNone ZN A1175 ( 2.3A) | 0.77A | 3v4tA-2clbA:undetectable3v4tD-2clbA:undetectable | 3v4tA-2clbA:18.763v4tD-2clbA:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dlq | GLI-KRUPPEL FAMILYMEMBER HKR3 (Mus musculus) |
PF00096(zf-C2H2)PF13894(zf-C2H2_4) | 3 | THR A 68VAL A 66GLU A 74 | None | 0.62A | 3v4tA-2dlqA:undetectable3v4tD-2dlqA:undetectable | 3v4tA-2dlqA:14.993v4tD-2dlqA:14.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ffj | CONSERVEDHYPOTHETICAL PROTEIN (Archaeoglobusfulgidus) |
PF01937(DUF89) | 3 | THR A 102VAL A 106GLU A 174 | None | 0.76A | 3v4tA-2ffjA:undetectable3v4tD-2ffjA:undetectable | 3v4tA-2ffjA:24.593v4tD-2ffjA:24.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gah | HETEROTETRAMERICSARCOSINE OXIDASEGAMMA-SUBUNIT (Stenotrophomonasmaltophilia) |
PF04268(SoxG) | 3 | THR C 79VAL C 81GLU C 75 | None | 0.68A | 3v4tA-2gahC:undetectable3v4tD-2gahC:undetectable | 3v4tA-2gahC:20.893v4tD-2gahC:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gai | DNA TOPOISOMERASE I (Thermotogamaritima) |
PF01131(Topoisom_bac)PF01751(Toprim) | 3 | THR A 381VAL A 398GLU A 379 | None | 0.72A | 3v4tA-2gaiA:undetectable3v4tD-2gaiA:undetectable | 3v4tA-2gaiA:22.843v4tD-2gaiA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsk | VITAMIN B12TRANSPORTER BTUBPROTEIN TONB (Escherichiacoli;Escherichiacoli) |
PF00593(TonB_dep_Rec)PF07715(Plug)PF03544(TonB_C) | 3 | THR A 11VAL A 9GLU B 173 | None | 0.64A | 3v4tA-2gskA:undetectable3v4tD-2gskA:undetectable | 3v4tA-2gskA:21.843v4tD-2gskA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpw | GREEN FLUORESCENTPROTEIN (Clytia gregaria) |
PF01353(GFP) | 3 | THR A 44VAL A 223GLU A 14 | None | 0.61A | 3v4tA-2hpwA:undetectable3v4tD-2hpwA:undetectable | 3v4tA-2hpwA:23.113v4tD-2hpwA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ivd | PROTOPORPHYRINOGENOXIDASE (Myxococcusxanthus) |
PF01593(Amino_oxidase) | 3 | THR A 99VAL A 97GLU A 336 | None | 0.71A | 3v4tA-2ivdA:undetectable3v4tD-2ivdA:undetectable | 3v4tA-2ivdA:25.293v4tD-2ivdA:25.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l8o | UNCHARACTERIZEDPROTEIN (Cytophagahutchinsonii) |
PF08327(AHSA1) | 3 | THR A 83VAL A 70GLU A 81 | None | 0.71A | 3v4tA-2l8oA:undetectable3v4tD-2l8oA:undetectable | 3v4tA-2l8oA:17.513v4tD-2l8oA:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mf9 | PEPTIDYL-PROLYLCIS-TRANS ISOMERASEFKBP8 (Homo sapiens) |
PF00254(FKBP_C) | 3 | THR A 146VAL A 148GLU A 85 | None | 0.76A | 3v4tA-2mf9A:undetectable3v4tD-2mf9A:undetectable | 3v4tA-2mf9A:17.423v4tD-2mf9A:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mpr | MALTOPORIN (Salmonellaenterica) |
PF02264(LamB) | 3 | THR A 216VAL A 231GLU A 188 | None | 0.77A | 3v4tA-2mprA:undetectable3v4tD-2mprA:undetectable | 3v4tA-2mprA:23.793v4tD-2mprA:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oxf | URIDINEPHOSPHORYLASE (Salmonellaenterica) |
PF01048(PNP_UDP_1) | 3 | THR A1233VAL A1221GLU A1238 | None | 0.54A | 3v4tA-2oxfA:undetectable3v4tD-2oxfA:undetectable | 3v4tA-2oxfA:21.903v4tD-2oxfA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q1f | CHONDROITINASE (Bacteroidesthetaiotaomicron) |
PF02278(Lyase_8)PF09092(Lyase_N)PF09093(Lyase_catalyt) | 3 | THR A 768VAL A 676GLU A 766 | None | 0.44A | 3v4tA-2q1fA:undetectable3v4tD-2q1fA:undetectable | 3v4tA-2q1fA:18.453v4tD-2q1fA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rkj | TYROSYL-TRNASYNTHETASE (Neurosporacrassa) |
PF00579(tRNA-synt_1b) | 3 | THR A 391VAL A 387GLU A 410 | None | 0.42A | 3v4tA-2rkjA:undetectable3v4tD-2rkjA:undetectable | 3v4tA-2rkjA:23.403v4tD-2rkjA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v7g | UROCANATE HYDRATASE (Pseudomonasputida) |
PF01175(Urocanase)PF17391(Urocanase_N)PF17392(Urocanase_C) | 3 | THR A 73VAL A 69GLU A 28 | None | 0.50A | 3v4tA-2v7gA:undetectable3v4tD-2v7gA:undetectable | 3v4tA-2v7gA:24.913v4tD-2v7gA:24.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wgn | INHIBITOR OFCYSTEINE PEPTIDASECOMPND 3 (Pseudomonasaeruginosa) |
PF09394(Inhibitor_I42) | 3 | THR B 27VAL B 25GLU B 71 | None | 0.69A | 3v4tA-2wgnB:undetectable3v4tD-2wgnB:undetectable | 3v4tA-2wgnB:16.353v4tD-2wgnB:16.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzk | OROTATEPHOSPHORIBOSYLTRANSFERASE (Aeropyrumpernix) |
PF00156(Pribosyltran) | 3 | THR A 117VAL A 115GLU A 147 | None | 0.63A | 3v4tA-2yzkA:undetectable3v4tD-2yzkA:undetectable | 3v4tA-2yzkA:20.533v4tD-2yzkA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z0m | 337AA LONGHYPOTHETICALATP-DEPENDENT RNAHELICASE DEAD (Sulfurisphaeratokodaii) |
PF00270(DEAD)PF00271(Helicase_C) | 3 | THR A 63VAL A 61GLU A 137 | None | 0.68A | 3v4tA-2z0mA:1.63v4tD-2z0mA:1.6 | 3v4tA-2z0mA:24.313v4tD-2z0mA:24.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zts | PUTATIVEUNCHARACTERIZEDPROTEIN PH0186 (Pyrococcushorikoshii) |
PF06745(ATPase) | 3 | THR A 36VAL A 202GLU A 195 | None | 0.71A | 3v4tA-2ztsA:undetectable3v4tD-2ztsA:undetectable | 3v4tA-2ztsA:22.383v4tD-2ztsA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ber | PROBABLEATP-DEPENDENT RNAHELICASE DDX47 (Homo sapiens) |
PF00270(DEAD) | 3 | THR A 99VAL A 97GLU A 175 | None | 0.69A | 3v4tA-3berA:1.23v4tD-3berA:1.3 | 3v4tA-3berA:19.443v4tD-3berA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmg | PUTATIVEBETA-GALACTOSIDASE (Bacteroidesfragilis) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF16355(DUF4982) | 3 | THR A 627VAL A 658GLU A 615 | None | 0.56A | 3v4tA-3cmgA:undetectable3v4tD-3cmgA:undetectable | 3v4tA-3cmgA:21.383v4tD-3cmgA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dhw | METHIONINE IMPORTATP-BINDING PROTEINMETN (Escherichiacoli) |
PF00005(ABC_tran)PF09383(NIL) | 3 | THR C 8VAL C 10GLU C 59 | None | 0.70A | 3v4tA-3dhwC:undetectable3v4tD-3dhwC:undetectable | 3v4tA-3dhwC:22.223v4tD-3dhwC:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e53 | FATTY-ACID-COALIGASE FADD28 (Mycobacteriumtuberculosis) |
PF00501(AMP-binding) | 3 | THR A 444VAL A 405GLU A 333 | None | 0.70A | 3v4tA-3e53A:undetectable3v4tD-3e53A:undetectable | 3v4tA-3e53A:23.483v4tD-3e53A:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egi | TRIMETHYLGUANOSINESYNTHASE HOMOLOG (Homo sapiens) |
PF09445(Methyltransf_15) | 3 | THR A 839VAL A 802GLU A 825 | None | 0.78A | 3v4tA-3egiA:undetectable3v4tD-3egiA:1.9 | 3v4tA-3egiA:20.773v4tD-3egiA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fh1 | UNCHARACTERIZEDNTF2-LIKE PROTEIN (Mesorhizobiumloti) |
PF12680(SnoaL_2) | 3 | THR A 93VAL A 109GLU A 84 | None | 0.64A | 3v4tA-3fh1A:undetectable3v4tD-3fh1A:undetectable | 3v4tA-3fh1A:15.043v4tD-3fh1A:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g64 | PUTATIVE ENOYL-COAHYDRATASE (Streptomycescoelicolor) |
PF00378(ECH_1) | 3 | THR A 22VAL A 25GLU A 20 | None | 0.71A | 3v4tA-3g64A:undetectable3v4tD-3g64A:undetectable | 3v4tA-3g64A:24.483v4tD-3g64A:24.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gc3 | BETA-ARRESTIN-1 (Bos taurus) |
PF00339(Arrestin_N)PF02752(Arrestin_C) | 3 | THR A 56VAL A 81GLU A 145 | None | 0.70A | 3v4tA-3gc3A:undetectable3v4tD-3gc3A:undetectable | 3v4tA-3gc3A:24.783v4tD-3gc3A:24.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hvs | THIOL PEROXIDASE (Escherichiacoli) |
PF08534(Redoxin) | 3 | THR A 29VAL A 31GLU A 113 | None | 0.78A | 3v4tA-3hvsA:undetectable3v4tD-3hvsA:undetectable | 3v4tA-3hvsA:19.093v4tD-3hvsA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iuy | PROBABLEATP-DEPENDENT RNAHELICASE DDX53 (Homo sapiens) |
PF00270(DEAD) | 3 | THR A 312VAL A 310GLU A 386 | None | 0.68A | 3v4tA-3iuyA:1.23v4tD-3iuyA:1.1 | 3v4tA-3iuyA:20.103v4tD-3iuyA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kve | L-AMINO ACID OXIDASE (Viperaammodytes) |
PF01593(Amino_oxidase) | 3 | THR A 431VAL A 319GLU A 219 | None | 0.73A | 3v4tA-3kveA:undetectable3v4tD-3kveA:undetectable | 3v4tA-3kveA:22.533v4tD-3kveA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kxw | SAFRAMYCIN MX1SYNTHETASE B (Legionellapneumophila) |
PF00501(AMP-binding) | 3 | THR A 438VAL A 402GLU A 329 | NoneNone1ZZ A 589 ( 4.9A) | 0.69A | 3v4tA-3kxwA:0.03v4tD-3kxwA:undetectable | 3v4tA-3kxwA:21.303v4tD-3kxwA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mcr | NADH DEHYDROGENASE,SUBUNIT C (Thermobifidafusca) |
PF00329(Complex1_30kDa) | 3 | THR A 109VAL A 102GLU A 107 | None | 0.69A | 3v4tA-3mcrA:undetectable3v4tD-3mcrA:undetectable | 3v4tA-3mcrA:20.753v4tD-3mcrA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mwj | HEAT RESISTANT RNADEPENDENT ATPASE (Thermusthermophilus) |
PF00270(DEAD) | 3 | THR A 79VAL A 77GLU A 152 | None | 0.61A | 3v4tA-3mwjA:0.93v4tD-3mwjA:0.9 | 3v4tA-3mwjA:21.093v4tD-3mwjA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3net | HISTIDYL-TRNASYNTHETASE (Nostoc sp. PCC7120) |
PF03129(HGTP_anticodon)PF13393(tRNA-synt_His) | 3 | THR A 311VAL A 178GLU A 309 | None | 0.76A | 3v4tA-3netA:undetectable3v4tD-3netA:undetectable | 3v4tA-3netA:23.633v4tD-3netA:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r75 | ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI (Burkholderialata) |
PF00117(GATase)PF00425(Chorismate_bind) | 3 | THR A 369VAL A 371GLU A 382 | BEZ A 701 (-4.1A)None MG A 700 ( 2.5A) | 0.72A | 3v4tA-3r75A:undetectable3v4tD-3r75A:undetectable | 3v4tA-3r75A:24.393v4tD-3r75A:24.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r9l | NUCLEOSIDEDIPHOSPHATE KINASE (Giardiaintestinalis) |
PF00334(NDK) | 3 | THR A 93VAL A 111GLU A 97 | None | 0.55A | 3v4tA-3r9lA:undetectable3v4tD-3r9lA:undetectable | 3v4tA-3r9lA:17.973v4tD-3r9lA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rby | UNCHARACTERIZEDPROTEIN YLR301W (Saccharomycescerevisiae) |
PF16815(HRI1) | 3 | THR A 98VAL A 70GLU A 108 | None | 0.76A | 3v4tA-3rbyA:undetectable3v4tD-3rbyA:undetectable | 3v4tA-3rbyA:19.863v4tD-3rbyA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wfz | LACTO-N-BIOSEPHOSPHORYLASE (Bifidobacteriumlongum) |
PF09508(Lact_bio_phlase)PF17385(LBP_M)PF17386(LBP_C) | 3 | THR A 150VAL A 116GLU A 148 | None | 0.76A | 3v4tA-3wfzA:undetectable3v4tD-3wfzA:undetectable | 3v4tA-3wfzA:20.423v4tD-3wfzA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wv4 | NON-RIBOSOMALPEPTIDE SYNTHETASE (Streptomyceshalstedii) |
PF00501(AMP-binding) | 3 | THR A 409VAL A 376GLU A 328 | None | 0.70A | 3v4tA-3wv4A:undetectable3v4tD-3wv4A:undetectable | 3v4tA-3wv4A:24.173v4tD-3wv4A:24.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wvn | NON-RIBOSOMALPEPTIDE SYNTHETASE (Streptomyceshalstedii) |
PF00501(AMP-binding) | 3 | THR A 409VAL A 376GLU A 328 | None | 0.71A | 3v4tA-3wvnA:undetectable3v4tD-3wvnA:undetectable | 3v4tA-3wvnA:23.673v4tD-3wvnA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zgx | CHROMOSOME PARTITIONPROTEIN SMCSEGREGATION ANDCONDENSATION PROTEINA (Bacillussubtilis;Bacillussubtilis) |
PF02463(SMC_N)PF02616(SMC_ScpA) | 3 | THR C 65VAL C 61GLU A 183 | None | 0.50A | 3v4tA-3zgxC:undetectable3v4tD-3zgxC:undetectable | 3v4tA-3zgxC:12.413v4tD-3zgxC:12.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zpp | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcuspneumoniae) |
PF12708(Pectate_lyase_3)PF13229(Beta_helix) | 3 | THR A 492VAL A 518GLU A 521 | None | 0.67A | 3v4tA-3zppA:undetectable3v4tD-3zppA:undetectable | 3v4tA-3zppA:22.363v4tD-3zppA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zq3 | OBP3 PROTEIN (Rattusnorvegicus) |
PF00061(Lipocalin) | 3 | THR A 108VAL A 125GLU A 106 | None | 0.72A | 3v4tA-3zq3A:undetectable3v4tD-3zq3A:undetectable | 3v4tA-3zq3A:20.153v4tD-3zq3A:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ac3 | BIFUNCTIONAL PROTEINGLMU (Streptococcuspneumoniae) |
PF00132(Hexapep)PF00483(NTP_transferase)PF14602(Hexapep_2) | 3 | THR A 310VAL A 308GLU A 275 | None | 0.60A | 3v4tA-4ac3A:undetectable3v4tD-4ac3A:undetectable | 3v4tA-4ac3A:23.733v4tD-4ac3A:23.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4af2 | THIOL PEROXIDASE (Escherichiacoli) |
PF08534(Redoxin) | 3 | THR A 29VAL A 31GLU A 113 | None | 0.77A | 3v4tA-4af2A:undetectable3v4tD-4af2A:undetectable | 3v4tA-4af2A:21.243v4tD-4af2A:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ay1 | CHITINASE-3-LIKEPROTEIN 2 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 3 | THR A 153VAL A 157GLU A 151 | None | 0.73A | 3v4tA-4ay1A:undetectable3v4tD-4ay1A:undetectable | 3v4tA-4ay1A:21.153v4tD-4ay1A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzg | ALDOSE 1-EPIMERASE (Bacillussubtilis) |
PF01263(Aldose_epim) | 3 | THR A 312VAL A 162GLU A 310 | None | 0.63A | 3v4tA-4bzgA:undetectable3v4tD-4bzgA:undetectable | 3v4tA-4bzgA:21.363v4tD-4bzgA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c51 | CATALASE-PEROXIDASE (Mycobacteriumtuberculosis) |
PF00141(peroxidase) | 3 | THR A 579VAL A 581GLU A 577 | None | 0.63A | 3v4tA-4c51A:undetectable3v4tD-4c51A:undetectable | 3v4tA-4c51A:21.603v4tD-4c51A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c6o | CAD PROTEIN (Homo sapiens) |
PF01979(Amidohydro_1) | 3 | THR A1595VAL A1599GLU A1620 | None | 0.71A | 3v4tA-4c6oA:1.93v4tD-4c6oA:1.4 | 3v4tA-4c6oA:23.683v4tD-4c6oA:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e3z | PUTATIVEOXIDOREDUCTASEPROTEIN (Rhizobium etli) |
PF13561(adh_short_C2) | 3 | THR A 50VAL A 46GLU A 55 | None | 0.61A | 3v4tA-4e3zA:undetectable3v4tD-4e3zA:undetectable | 3v4tA-4e3zA:22.543v4tD-4e3zA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fbz | DELTARHODOPSIN (Haloterrigenathermotolerans) |
PF01036(Bac_rhodopsin) | 3 | THR A 76VAL A 65GLU A 193 | None | 0.58A | 3v4tA-4fbzA:undetectable3v4tD-4fbzA:undetectable | 3v4tA-4fbzA:18.203v4tD-4fbzA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jo8 | M157 (Muridbetaherpesvirus1) |
PF11624(M157) | 3 | THR A 251VAL A 218GLU A 244 | None | 0.72A | 3v4tA-4jo8A:undetectable3v4tD-4jo8A:undetectable | 3v4tA-4jo8A:22.723v4tD-4jo8A:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kha | SPT16M-HISTONE H2B1.1 CHIMERA (Xenopus laevis;Chaetomiumthermophilum) |
PF00125(Histone)PF08512(Rtt106)PF08644(SPT16) | 3 | THR A 851VAL A 849GLU A 837 | None | 0.77A | 3v4tA-4khaA:undetectable3v4tD-4khaA:undetectable | 3v4tA-4khaA:22.083v4tD-4khaA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kho | UNCHARACTERIZEDPROTEIN SPT16M (Chaetomiumthermophilum) |
PF08512(Rtt106)PF08644(SPT16) | 3 | THR A 853VAL A 851GLU A 839 | None | 0.75A | 3v4tA-4khoA:undetectable3v4tD-4khoA:undetectable | 3v4tA-4khoA:21.133v4tD-4khoA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l15 | FIDGETIN-LIKEPROTEIN 1 (Caenorhabditiselegans) |
PF00004(AAA)PF09336(Vps4_C) | 3 | THR A 437VAL A 441GLU A 394 | None | 0.59A | 3v4tA-4l15A:undetectable3v4tD-4l15A:1.1 | 3v4tA-4l15A:24.483v4tD-4l15A:24.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mr0 | PLASMIN ANDFIBRONECTIN-BINDINGPROTEIN A (Streptococcuspneumoniae) |
PF12708(Pectate_lyase_3)PF13229(Beta_helix) | 3 | THR A 503VAL A 529GLU A 532 | None | 0.57A | 3v4tA-4mr0A:undetectable3v4tD-4mr0A:undetectable | 3v4tA-4mr0A:21.173v4tD-4mr0A:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ovj | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Alicyclobacillusacidocaldarius) |
PF13416(SBP_bac_8) | 3 | THR A 49VAL A 47GLU A 72 | None | 0.66A | 3v4tA-4ovjA:undetectable3v4tD-4ovjA:undetectable | 3v4tA-4ovjA:22.633v4tD-4ovjA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rdj | CAPSID (Norwalk virus) |
PF00915(Calici_coat)PF08435(Calici_coat_C) | 3 | THR A 336VAL A 338GLU A 389 | None | 0.74A | 3v4tA-4rdjA:undetectable3v4tD-4rdjA:undetectable | 3v4tA-4rdjA:20.923v4tD-4rdjA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rzk | SMALL HEAT SHOCKPROTEIN HSP20 FAMILY (Sulfolobussolfataricus) |
PF00011(HSP20) | 3 | THR A 124VAL A 122GLU A 82 | None | 0.54A | 3v4tA-4rzkA:undetectable3v4tD-4rzkA:undetectable | 3v4tA-4rzkA:13.593v4tD-4rzkA:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3j | CORTICAL-LYTICENZYME (Bacillus cereus) |
PF00704(Glyco_hydro_18)PF01476(LysM) | 3 | THR A 173VAL A 171GLU A 219 | None | 0.69A | 3v4tA-4s3jA:undetectable3v4tD-4s3jA:undetectable | 3v4tA-4s3jA:22.273v4tD-4s3jA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zk3 | SERPIN B3 (Homo sapiens) |
PF00079(Serpin) | 3 | THR A 172VAL A 175GLU A 110 | None | 0.78A | 3v4tA-4zk3A:undetectable3v4tD-4zk3A:undetectable | 3v4tA-4zk3A:21.383v4tD-4zk3A:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c3u | L-SERINEAMMONIA-LYASE (Rhizomucormiehei) |
PF00291(PALP) | 3 | THR A 127VAL A 131GLU A 124 | None | 0.71A | 3v4tA-5c3uA:undetectable3v4tD-5c3uA:undetectable | 3v4tA-5c3uA:24.363v4tD-5c3uA:24.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5chv | UBLCARBOXYL-TERMINALHYDROLASE 18 (Mus musculus) |
PF00443(UCH) | 3 | THR A 179VAL A 176GLU A 181 | None | 0.73A | 3v4tA-5chvA:undetectable3v4tD-5chvA:undetectable | 3v4tA-5chvA:21.233v4tD-5chvA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fr8 | TONB-DEPENDENTSIDEROPHORE RECEPTOR (Acinetobacterbaumannii) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | THR A 42VAL A 40GLU A 130 | None | 0.68A | 3v4tA-5fr8A:undetectable3v4tD-5fr8A:undetectable | 3v4tA-5fr8A:21.203v4tD-5fr8A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j7x | DIMETHYLANILINEMONOOXYGENASE,PUTATIVE (Aspergillusflavus) |
PF00743(FMO-like) | 3 | THR A 128VAL A 136GLU A 117 | None | 0.71A | 3v4tA-5j7xA:undetectable3v4tD-5j7xA:undetectable | 3v4tA-5j7xA:23.133v4tD-5j7xA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ja1 | ENTEROBACTINSYNTHASE COMPONENT F (Escherichiacoli) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 3 | THR A 690VAL A 687GLU A 653 | None | 0.74A | 3v4tA-5ja1A:undetectable3v4tD-5ja1A:undetectable | 3v4tA-5ja1A:16.163v4tD-5ja1A:16.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjd | COLLAGEN TYPE IVALPHA-3-BINDINGPROTEIN (Homo sapiens) |
PF01852(START) | 3 | THR B 531VAL B 533GLU B 498 | None | 0.69A | 3v4tA-5jjdB:undetectable3v4tD-5jjdB:undetectable | 3v4tA-5jjdB:21.993v4tD-5jjdB:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8d | COAGULATION FACTORVIII (Homo sapiens) |
PF00394(Cu-oxidase)PF07732(Cu-oxidase_3) | 3 | THR A 135VAL A 137GLU A 124 | None | 0.63A | 3v4tA-5k8dA:undetectable3v4tD-5k8dA:undetectable | 3v4tA-5k8dA:22.033v4tD-5k8dA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mmj | RIBOSOME-BINDINGFACTOR PSRP1,CHLOROPLASTIC (Spinaciaoleracea) |
no annotation | 3 | THR y 135VAL y 143GLU y 111 | None G a 915 ( 4.6A)None | 0.75A | 3v4tA-5mmjy:undetectable3v4tD-5mmjy:undetectable | 3v4tA-5mmjy:22.923v4tD-5mmjy:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5msn | DCC1 PROTEIN (Saccharomycescerevisiae) |
PF09724(Dcc1) | 3 | THR A 375VAL A 377GLU A 342 | None | 0.70A | 3v4tA-5msnA:undetectable3v4tD-5msnA:undetectable | 3v4tA-5msnA:21.993v4tD-5msnA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n9m | COBYRIC ACIDSYNTHASE (Staphylococcusaureus) |
no annotation | 3 | THR A 142VAL A 144GLU A 198 | None | 0.68A | 3v4tA-5n9mA:undetectable3v4tD-5n9mA:undetectable | 3v4tA-5n9mA:undetectable3v4tD-5n9mA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5owj | TRIGGER FACTOR (Escherichiacoli) |
no annotation | 3 | THR A 422VAL A 130GLU A 126 | None | 0.75A | 3v4tA-5owjA:undetectable3v4tD-5owjA:undetectable | 3v4tA-5owjA:23.613v4tD-5owjA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t8v | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF12765(Cohesin_HEAT)PF12830(Nipped-B_C) | 3 | THR A 600VAL A 598GLU A 533 | None | 0.63A | 3v4tA-5t8vA:undetectable3v4tD-5t8vA:undetectable | 3v4tA-5t8vA:16.053v4tD-5t8vA:16.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ts5 | AMINE OXIDASE (Bothrops atrox) |
PF01593(Amino_oxidase) | 3 | THR A 431VAL A 319GLU A 219 | None | 0.74A | 3v4tA-5ts5A:undetectable3v4tD-5ts5A:undetectable | 3v4tA-5ts5A:22.943v4tD-5ts5A:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v8d | BACILLUS CEREUSPATB1 (Bacillus cereus) |
no annotation | 3 | THR C 280VAL C 288GLU C 317 | None | 0.68A | 3v4tA-5v8dC:undetectable3v4tD-5v8dC:undetectable | 3v4tA-5v8dC:21.953v4tD-5v8dC:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ve8 | KAP123 (Kluyveromyceslactis) |
no annotation | 3 | THR A 427VAL A 423GLU A 469 | None | 0.40A | 3v4tA-5ve8A:undetectable3v4tD-5ve8A:undetectable | 3v4tA-5ve8A:17.813v4tD-5ve8A:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wmm | NRPS (Micromonosporasp. ML1) |
no annotation | 3 | THR A 396VAL A 361GLU A 310 | None | 0.78A | 3v4tA-5wmmA:1.83v4tD-5wmmA:1.6 | 3v4tA-5wmmA:undetectable3v4tD-5wmmA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x8r | PROTEIN PLASTID PY (Spinaciaoleracea) |
no annotation | 3 | THR y 135VAL y 143GLU y 111 | G a 915 ( 4.7A)None C a1178 ( 4.7A) | 0.66A | 3v4tA-5x8ry:undetectable3v4tD-5x8ry:undetectable | 3v4tA-5x8ry:19.153v4tD-5x8ry:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yj6 | DOCKERIN TYPE IREPEAT-CONTAININGPROTEIN (Ruminiclostridiumthermocellum) |
no annotation | 3 | THR A 111VAL A 115GLU A 96 | None | 0.63A | 3v4tA-5yj6A:undetectable3v4tD-5yj6A:undetectable | 3v4tA-5yj6A:undetectable3v4tD-5yj6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MONOVALENT CATION/H+ANTIPORTER SUBUNIT D (Pyrococcusfuriosus) |
no annotation | 3 | THR H 92VAL H 88GLU H 123 | None | 0.67A | 3v4tA-6cfwH:undetectable3v4tD-6cfwH:undetectable | 3v4tA-6cfwH:undetectable3v4tD-6cfwH:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 9pcy | PLASTOCYANIN (Phaseolusvulgaris) |
PF00127(Copper-bind) | 3 | THR A 73VAL A 71GLU A 25 | None | 0.67A | 3v4tA-9pcyA:undetectable3v4tD-9pcyA:undetectable | 3v4tA-9pcyA:13.973v4tD-9pcyA:13.97 |