SIMILAR PATTERNS OF AMINO ACIDS FOR 3V4T_A_ACTA503_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a2v METHYLAMINE OXIDASE

(Ogataea angusta) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		3 ARG A 352
GLU A 199
THR A 198
 None
 0.82A 3v4tA-1a2vA:
0.0		 3v4tA-1a2vA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eqw CU,ZN SUPEROXIDE
DISMUTASE

(Salmonella
enterica) 		PF00080
(Sod_Cu) 		3 ARG A 101
GLU A  65
THR A  67
 None
 0.84A 3v4tA-1eqwA:
0.0		 3v4tA-1eqwA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1euj ENDOTHELIAL MONOCYTE
ACTIVATING
POLYPEPTIDE 2

(Homo sapiens) 		PF01588
(tRNA_bind) 		3 ARG A  20
GLU A  31
THR A  42
 None
 0.91A 3v4tA-1eujA:
0.0		 3v4tA-1eujA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezr NUCLEOSIDE HYDROLASE

(Leishmania
major) 		PF01156
(IU_nuc_hydro) 		3 ARG A 258
GLU A 257
THR A 256
 None
 0.87A 3v4tA-1ezrA:
1.2		 3v4tA-1ezrA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lpc DIANTHIN 30

(Dianthus
caryophyllus) 		PF00161
(RIP) 		3 ARG A 166
GLU A 139
THR A 131
 None
 0.77A 3v4tA-1lpcA:
0.0		 3v4tA-1lpcA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofm CHONDROITINASE B

(Pedobacter
heparinus) 		PF14592
(Chondroitinas_B) 		3 ARG A 108
GLU A 140
THR A 172
 None
 0.93A 3v4tA-1ofmA:
0.0		 3v4tA-1ofmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1olp ALPHA-TOXIN

(Clostridium
sardiniense) 		PF00882
(Zn_dep_PLPC)
PF01477
(PLAT) 		3 ARG A 163
GLU A  20
THR A  16
 None
 0.91A 3v4tA-1olpA:
0.0		 3v4tA-1olpA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdq TENASCIN-R

(Rattus
norvegicus) 		PF00041
(fn3) 		3 ARG A  69
GLU A  71
THR A  88
 None
 0.90A 3v4tA-1tdqA:
0.0		 3v4tA-1tdqA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tht THIOESTERASE

(Vibrio harveyi) 		PF02273
(Acyl_transf_2) 		3 ARG A  67
GLU A  24
THR A   7
 None
 0.92A 3v4tA-1thtA:
0.0		 3v4tA-1thtA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		3 ARG A 753
GLU A 444
THR A 445
 None
 0.91A 3v4tA-1v7vA:
undetectable		 3v4tA-1v7vA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1l PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
BETA ISOFORM

(Rattus
norvegicus) 		PF02121
(IP_trans) 		3 ARG A 244
GLU A  46
THR A  58
 None
None
PCW  A 501 (-3.8A)
 0.89A 3v4tA-2a1lA:
undetectable		 3v4tA-2a1lA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2arh HYPOTHETICAL PROTEIN
AQ_1966

(Aquifex
aeolicus) 		PF06557
(DUF1122) 		3 ARG A 163
GLU A 158
THR A 157
 None
 0.78A 3v4tA-2arhA:
2.7		 3v4tA-2arhA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c7i PUTATIVE LIPOATE
PROTEIN LIGASE

(Thermoplasma
acidophilum) 		PF03099
(BPL_LplA_LipB) 		3 ARG A  37
GLU A   9
THR A  10
 None
 0.76A 3v4tA-2c7iA:
undetectable		 3v4tA-2c7iA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d6f GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT E

(Methanothermobacter
thermautotrophicus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N)
PF02938
(GAD) 		3 ARG C 165
GLU C 166
THR C 167
 None
 0.80A 3v4tA-2d6fC:
undetectable		 3v4tA-2d6fC:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eax PEPTIDOGLYCAN
RECOGNITION
PROTEIN-I-BETA

(Homo sapiens) 		PF01510
(Amidase_2) 		3 ARG A 216
GLU A 223
THR A 224
 None
 0.84A 3v4tA-2eaxA:
undetectable		 3v4tA-2eaxA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1

(Elizabethkingia
meningoseptica) 		PF00704
(Glyco_hydro_18) 		3 ARG A 255
GLU A  17
THR A  21
 None
 0.89A 3v4tA-2ebnA:
undetectable		 3v4tA-2ebnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ef4 ARGINASE

(Thermus
thermophilus) 		PF00491
(Arginase) 		3 ARG A 177
GLU A 175
THR A 126
 None
 0.88A 3v4tA-2ef4A:
undetectable		 3v4tA-2ef4A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fbe PREDICTED: SIMILAR
TO RET FINGER
PROTEIN-LIKE 1

(Homo sapiens) 		PF00622
(SPRY)
PF13765
(PRY) 		3 ARG A 165
GLU A  46
THR A  18
 None
 0.72A 3v4tA-2fbeA:
undetectable		 3v4tA-2fbeA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iwg 52 KDA RO PROTEIN

(Homo sapiens) 		PF00622
(SPRY)
PF13765
(PRY) 		3 ARG B 160
GLU B  40
THR B  12
 None
 0.80A 3v4tA-2iwgB:
undetectable		 3v4tA-2iwgB:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4r EXOPOLYPHOSPHATASE

(Aquifex
aeolicus) 		PF02541
(Ppx-GppA) 		3 ARG A 121
GLU A 119
THR A 115
 None
G4P  A1307 ( 4.5A)
None
 0.78A 3v4tA-2j4rA:
undetectable		 3v4tA-2j4rA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o7p RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBD

(Escherichia
coli) 		PF00383
(dCMP_cyt_deam_1)
PF01872
(RibD_C) 		3 ARG A 229
GLU A 250
THR A 266
 None
 0.74A 3v4tA-2o7pA:
undetectable		 3v4tA-2o7pA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2owm RELATED TO
KINESIN-LIKE PROTEIN
KIF1C

(Neurospora
crassa) 		PF00225
(Kinesin) 		3 ARG A  56
GLU A  59
THR A 395
 None
 0.91A 3v4tA-2owmA:
0.5		 3v4tA-2owmA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p17 PIRIN-LIKE PROTEIN

(Geobacillus
kaustophilus) 		PF02678
(Pirin)
PF05726
(Pirin_C) 		3 ARG A 128
GLU A 126
THR A 125
 None
 0.82A 3v4tA-2p17A:
undetectable		 3v4tA-2p17A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q4a CLAVAMINATE
SYNTHASE-LIKE
PROTEIN AT3G21360

(Arabidopsis
thaliana) 		PF02668
(TauD) 		3 ARG A 322
GLU A 146
THR A 147
 SO4  A 801 (-3.3A)
None
SO4  A 801 (-2.7A)
 0.73A 3v4tA-2q4aA:
undetectable		 3v4tA-2q4aA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q66 POLY(A) POLYMERASE

(Saccharomyces
cerevisiae) 		PF01909
(NTP_transf_2)
PF04926
(PAP_RNA-bind)
PF04928
(PAP_central) 		3 ARG A 510
GLU A 434
THR A 433
 None
 0.79A 3v4tA-2q66A:
undetectable		 3v4tA-2q66A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdy BH0842 PROTEIN

(Bacillus
halodurans) 		PF14498
(Glyco_hyd_65N_2) 		3 ARG A 723
GLU A 383
THR A 384
 None
 0.81A 3v4tA-2rdyA:
undetectable		 3v4tA-2rdyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rq7 ATP SYNTHASE EPSILON
CHAIN

(Spinacia
oleracea;
Thermosynechococcus
elongatus) 		PF00401
(ATP-synt_DE)
PF02823
(ATP-synt_DE_N) 		3 ARG A 120
GLU A  91
THR A  95
 None
 0.78A 3v4tA-2rq7A:
undetectable		 3v4tA-2rq7A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ve7 KINETOCHORE PROTEIN
HEC1, KINETOCHORE
PROTEIN SPC25
KINETOCHORE PROTEIN
NUF2, KINETOCHORE
PROTEIN SPC24

(Homo sapiens;
Homo sapiens) 		PF03801
(Ndc80_HEC)
PF08234
(Spindle_Spc25)
PF03800
(Nuf2)
PF08286
(Spc24) 		3 ARG C 131
GLU A 216
THR A 215
 None
 0.89A 3v4tA-2ve7C:
undetectable		 3v4tA-2ve7C:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vyo POLYSACCHARIDE
DEACETYLASE
DOMAIN-CONTAINING
PROTEIN ECU11_0510

(Encephalitozoon
cuniculi) 		PF01522
(Polysacc_deac_1) 		3 ARG A 123
GLU A 121
THR A 120
 None
IMD  A1229 ( 4.7A)
None
 0.81A 3v4tA-2vyoA:
undetectable		 3v4tA-2vyoA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wtz UDP-N-ACETYLMURAMOYL
-L-ALANYL-D-GLUTAMAT
E--2,6-DIAMINOPIMELA
TE LIGASE

(Mycobacterium
tuberculosis) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		3 ARG A 521
GLU A 506
THR A 507
 None
 0.90A 3v4tA-2wtzA:
undetectable		 3v4tA-2wtzA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x9x CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
pneumoniae) 		PF16569
(GramPos_pilinBB)
PF16570
(GramPos_pilinD3) 		3 ARG A 242
GLU A 272
THR A 271
 None
 0.93A 3v4tA-2x9xA:
undetectable		 3v4tA-2x9xA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x9z CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
pneumoniae) 		PF16569
(GramPos_pilinBB)
PF16570
(GramPos_pilinD3) 		3 ARG A 242
GLU A 272
THR A 271
 None
 0.91A 3v4tA-2x9zA:
undetectable		 3v4tA-2x9zA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xf8 D-ERYTHROSE-4-PHOSPH
ATE DEHYDROGENASE

(Escherichia
coli) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 ARG A  22
GLU A  24
THR A   0
 None
 0.84A 3v4tA-2xf8A:
undetectable		 3v4tA-2xf8A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyz SUGAR ABC
TRANSPORTER,
ATP-BINDING PROTEIN

(Thermotoga
maritima) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		3 ARG A 258
GLU A 317
THR A 316
 None
 0.92A 3v4tA-2yyzA:
undetectable		 3v4tA-2yyzA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium) 		PF13469
(Sulfotransfer_3) 		3 ARG A 345
GLU A 343
THR A 339
 None
 0.93A 3v4tA-2z6vA:
undetectable		 3v4tA-2z6vA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ak4 NADH-DEPENDENT
QUINUCLIDINONE
REDUCTASE

(Agrobacterium
tumefaciens) 		PF13561
(adh_short_C2) 		3 ARG A 196
GLU A 195
THR A 191
 NAD  A 901 (-3.4A)
None
NAD  A 901 (-2.8A)
 0.74A 3v4tA-3ak4A:
undetectable		 3v4tA-3ak4A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al0 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermotoga
maritima) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		3 ARG B 250
GLU B 251
THR B 252
 None
 0.79A 3v4tA-3al0B:
undetectable		 3v4tA-3al0B:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bni PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
coelicolor) 		PF00440
(TetR_N) 		3 ARG A 142
GLU A  82
THR A  85
 None
 0.91A 3v4tA-3bniA:
undetectable		 3v4tA-3bniA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c7o ENDO-1,4-BETA-XYLANA
SE

(Bacillus
subtilis) 		PF03422
(CBM_6)
PF04616
(Glyco_hydro_43) 		3 ARG A  33
GLU A 359
THR A 362
 None
CA  A 488 (-3.4A)
None
 0.79A 3v4tA-3c7oA:
undetectable		 3v4tA-3c7oA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cdi POLYNUCLEOTIDE
PHOSPHORYLASE

(Escherichia
coli) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		3 ARG A 106
GLU A  88
THR A  90
 None
 0.69A 3v4tA-3cdiA:
undetectable		 3v4tA-3cdiA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eoq PUTATIVE ZINC
PROTEASE

(Thermus
thermophilus) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		3 ARG A 176
GLU A  37
THR A  38
 None
 0.91A 3v4tA-3eoqA:
undetectable		 3v4tA-3eoqA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gqi PHOSPHOLIPASE
C-GAMMA-1

(Rattus
norvegicus) 		PF00017
(SH2) 		3 ARG B 562
GLU B 589
THR B 590
 None
 0.80A 3v4tA-3gqiB:
undetectable		 3v4tA-3gqiB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 1
NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 3

(Thermus
thermophilus;
Thermus
thermophilus) 		PF01512
(Complex1_51K)
PF10531
(SLBB)
PF10589
(NADH_4Fe-4S)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
PF10588
(NADH-G_4Fe-4S_3)
PF13510
(Fer2_4) 		3 ARG 1 196
GLU 3 204
THR 3 209
 None
 0.79A 3v4tA-3i9v1:
undetectable		 3v4tA-3i9v1:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igo CALMODULIN-DOMAIN
PROTEIN KINASE 1

(Cryptosporidium
parvum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		3 ARG A 169
GLU A 172
THR A 300
 None
 0.86A 3v4tA-3igoA:
undetectable		 3v4tA-3igoA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iuk UNCHARACTERIZED
PROTEIN

(Paenarthrobacter
aurescens) 		PF05960
(DUF885) 		3 ARG A 135
GLU A  42
THR A  34
 None
 0.94A 3v4tA-3iukA:
undetectable		 3v4tA-3iukA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j0h PHIKZ029

(Pseudomonas
virus phiKZ) 		no annotation 3 ARG A 315
GLU A 338
THR A 229
 None
 0.85A 3v4tA-3j0hA:
undetectable		 3v4tA-3j0hA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j15 PROTEIN PELOTA

(Pyrococcus
furiosus) 		PF03463
(eRF1_1)
PF03464
(eRF1_2)
PF03465
(eRF1_3) 		3 ARG A 152
GLU A  18
THR A  19
 None
 0.79A 3v4tA-3j15A:
undetectable		 3v4tA-3j15A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ju8 SUCCINYLGLUTAMIC
SEMIALDEHYDE
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00171
(Aldedh) 		3 ARG A 278
GLU A  99
THR A  98
 SIN  A 504 (-4.2A)
None
None
 0.90A 3v4tA-3ju8A:
undetectable		 3v4tA-3ju8A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l3p IPAH9.8

(Shigella
flexneri) 		PF14496
(NEL) 		3 ARG A 490
GLU A 517
THR A 518
 None
 0.86A 3v4tA-3l3pA:
undetectable		 3v4tA-3l3pA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpx DNA GYRASE, A
SUBUNIT

(Colwellia
psychrerythraea) 		PF00521
(DNA_topoisoIV) 		3 ARG A 358
GLU A 360
THR A 142
 None
 0.90A 3v4tA-3lpxA:
undetectable		 3v4tA-3lpxA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mru AMINOACYL-HISTIDINE
DIPEPTIDASE

(Vibrio
alginolyticus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		3 ARG A 198
GLU A 358
THR A 357
 None
 0.68A 3v4tA-3mruA:
undetectable		 3v4tA-3mruA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mv3 COATOMER SUBUNIT
ALPHA

(Saccharomyces
cerevisiae) 		PF06957
(COPI_C) 		3 ARG A 951
GLU A 900
THR A 901
 None
 0.70A 3v4tA-3mv3A:
undetectable		 3v4tA-3mv3A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p3l CYTOCHROME P450

(Streptomyces
thioluteus) 		PF00067
(p450) 		3 ARG A  42
GLU A   8
THR A   7
 None
None
SO4  A 408 (-4.8A)
 0.82A 3v4tA-3p3lA:
undetectable		 3v4tA-3p3lA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p4s FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT

(Escherichia
coli) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		3 ARG A 114
GLU A 245
THR A 244
 None
3NP  A 602 (-4.5A)
3NP  A 602 (-4.5A)
 0.84A 3v4tA-3p4sA:
undetectable		 3v4tA-3p4sA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pc3 CG1753, ISOFORM A

(Drosophila
melanogaster) 		PF00291
(PALP)
PF00571
(CBS) 		3 ARG A 455
GLU A 140
THR A 162
 None
 0.91A 3v4tA-3pc3A:
undetectable		 3v4tA-3pc3A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pl0 UNCHARACTERIZED
PROTEIN

(Methylibium
petroleiphilum) 		PF10014
(2OG-Fe_Oxy_2) 		3 ARG A 237
GLU A 186
THR A 187
 None
 0.93A 3v4tA-3pl0A:
1.6		 3v4tA-3pl0A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rv6 ISOCHORISMATE
SYNTHASE/ISOCHORISMA
TE-PYRUVATE LYASE
MBTI

(Mycobacterium
tuberculosis) 		PF00425
(Chorismate_bind) 		3 ARG A  75
GLU A 102
THR A 103
 None
 0.88A 3v4tA-3rv6A:
undetectable		 3v4tA-3rv6A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0f BETA-KETOACYL
SYNTHASE

(Brucella
abortus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 ARG A   2
GLU A 242
THR A 243
 None
 0.92A 3v4tA-3u0fA:
undetectable		 3v4tA-3u0fA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD

(Pseudomonas
aeruginosa) 		PF14467
(DUF4426) 		3 ARG A 110
GLU A 111
THR A 112
 None
 0.76A 3v4tA-3uc2A:
undetectable		 3v4tA-3uc2A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ulk KETOL-ACID
REDUCTOISOMERASE

(Escherichia
coli) 		PF01450
(IlvC)
PF07991
(IlvN) 		3 ARG A 276
GLU A 263
THR A 260
 ARG  A 276 ( 0.6A)
GLU  A 263 ( 0.6A)
THR  A 260 ( 0.8A)
 0.79A 3v4tA-3ulkA:
undetectable		 3v4tA-3ulkA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3upy OXIDOREDUCTASE

(Brucella
abortus) 		PF03447
(NAD_binding_3) 		3 ARG A  86
GLU A  81
THR A  80
 None
 0.82A 3v4tA-3upyA:
undetectable		 3v4tA-3upyA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vax PUTATIVE
UNCHARACTERIZED
PROTEIN DNDA

(Streptomyces
lividans) 		PF00266
(Aminotran_5) 		3 ARG A 236
GLU A  62
THR A 212
 None
 0.74A 3v4tA-3vaxA:
1.0		 3v4tA-3vaxA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aw5 EPHRIN TYPE-B
RECEPTOR 4

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 ARG A 132
GLU A 131
THR A 130
 None
 0.72A 3v4tA-4aw5A:
undetectable		 3v4tA-4aw5A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ckk DNA GYRASE SUBUNIT A

(Escherichia
coli) 		PF00521
(DNA_topoisoIV) 		3 ARG A 358
GLU A 360
THR A 142
 None
 0.86A 3v4tA-4ckkA:
undetectable		 3v4tA-4ckkA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4efz METALLO-BETA-LACTAMA
SE FAMILY PROTEIN

(Burkholderia
pseudomallei) 		PF00753
(Lactamase_B) 		3 ARG A 232
GLU A 230
THR A 226
 None
 0.92A 3v4tA-4efzA:
undetectable		 3v4tA-4efzA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gox POLYKETIDE SYNTHASE

(Synechococcus
sp. PCC 7002) 		PF13469
(Sulfotransfer_3) 		3 ARG A 141
GLU A 148
THR A 207
 None
 0.94A 3v4tA-4goxA:
undetectable		 3v4tA-4goxA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3s OUTER DOMAIN OF
HIV-1 GP120 (KER2018
OD4.2.2)

(Human
immunodeficiency
virus) 		PF00516
(GP120) 		3 ARG G 350
GLU G 397
THR G 399
 None
 0.91A 3v4tA-4i3sG:
undetectable		 3v4tA-4i3sG:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jb3 HALOACID
DEHALOGENASE-LIKE
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF13419
(HAD_2) 		3 ARG A  69
GLU A  70
THR A  72
 None
 0.87A 3v4tA-4jb3A:
undetectable		 3v4tA-4jb3A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jbb PUTATIVE GLUTATHIONE
S-TRANSFERASE

(Klebsiella
pneumoniae) 		PF13417
(GST_N_3)
PF14834
(GST_C_4) 		3 ARG A 110
GLU A  77
THR A  76
 GSH  A 301 (-4.8A)
None
None
 0.89A 3v4tA-4jbbA:
undetectable		 3v4tA-4jbbA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k2h INTRACELLULAR
PROTEASE/AMIDASE

(Salmonella
enterica) 		PF01965
(DJ-1_PfpI) 		3 ARG A  25
GLU A  32
THR A  33
 None
 0.77A 3v4tA-4k2hA:
undetectable		 3v4tA-4k2hA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k68 GH10 XYLANASE

(soil metagenome) 		PF00331
(Glyco_hydro_10) 		3 ARG A 363
GLU A 343
THR A 344
 None
 0.93A 3v4tA-4k68A:
undetectable		 3v4tA-4k68A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kna N-SUCCINYLGLUTAMATE
5-SEMIALDEHYDE
DEHYDROGENASE

(Burkholderia
thailandensis) 		PF00171
(Aldedh) 		3 ARG A 277
GLU A  98
THR A  97
 None
 0.88A 3v4tA-4knaA:
0.0		 3v4tA-4knaA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mc0 PUTATIVE
SESQUITERPENE
CYCLASE

(Kitasatospora
setae) 		no annotation 3 ARG A  46
GLU A  41
THR A  40
 None
 0.89A 3v4tA-4mc0A:
undetectable		 3v4tA-4mc0A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0l PREDICTED COMPONENT
OF A
THERMOPHILE-SPECIFIC
DNA REPAIR SYSTEM,
CONTAINS A RAMP
DOMAIN

(Methanopyrus
kandleri) 		PF03787
(RAMPs) 		3 ARG A  40
GLU A 196
THR A 195
 None
 0.93A 3v4tA-4n0lA:
undetectable		 3v4tA-4n0lA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pw1 UNCHARACTERIZED
PROTEIN

([Clostridium]
leptum) 		no annotation 3 ARG A 151
GLU A 152
THR A 154
 None
 0.80A 3v4tA-4pw1A:
undetectable		 3v4tA-4pw1A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6k BNR/ASP-BOX REPEAT
PROTEIN

(Bacteroides
caccae) 		PF13088
(BNR_2)
PF14873
(BNR_assoc_N) 		3 ARG A 102
GLU A 100
THR A  99
 None
 0.94A 3v4tA-4q6kA:
undetectable		 3v4tA-4q6kA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rlr CYTOCHROME C, 1
HEME-BINDING SITE

(Geobacter
sulfurreducens) 		no annotation 3 ARG A  97
GLU A  92
THR A  91
 None
 0.87A 3v4tA-4rlrA:
undetectable		 3v4tA-4rlrA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tza FLUORESCENT PROTEIN

(synthetic
construct) 		no annotation 3 ARG C 194
GLU C 211
THR C  37
 None
CRQ  C  62 ( 3.5A)
None
 0.88A 3v4tA-4tzaC:
undetectable		 3v4tA-4tzaC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxm TRANSCRIPTIONAL
REGULATOR FLEQ

(Pseudomonas
aeruginosa) 		PF06490
(FleQ) 		3 ARG A  50
GLU A  51
THR A   5
 None
 0.71A 3v4tA-4wxmA:
undetectable		 3v4tA-4wxmA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ye9 GLUTAMINE--TRNA
LIGASE

(Homo sapiens) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C)
PF04557
(tRNA_synt_1c_R2)
PF04558
(tRNA_synt_1c_R1) 		3 ARG A 154
GLU A  84
THR A  83
 None
 0.84A 3v4tA-4ye9A:
undetectable		 3v4tA-4ye9A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhb IRON-CHELATOR
UTILIZATION PROTEIN

(Thermobifida
fusca) 		PF04954
(SIP)
PF08021
(FAD_binding_9) 		3 ARG A 242
GLU A 215
THR A 214
 None
 0.85A 3v4tA-4yhbA:
undetectable		 3v4tA-4yhbA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z1o PHOSPHORIBOSYLTRANSF
ERASE

(Sulfolobus
solfataricus) 		PF00156
(Pribosyltran) 		3 ARG A  65
GLU A 100
THR A 101
 PRP  A 201 (-2.8A)
None
PRP  A 201 (-3.5A)
 0.62A 3v4tA-4z1oA:
undetectable		 3v4tA-4z1oA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dot CARBAMOYL-PHOSPHATE
SYNTHASE [AMMONIA],
MITOCHONDRIAL

(Homo sapiens) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain)
PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		3 ARG A 233
GLU A 379
THR A 381
 None
 0.86A 3v4tA-5dotA:
undetectable		 3v4tA-5dotA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gnw BLR0248 PROTEIN

(Bradyrhizobium
diazoefficiens) 		no annotation 3 ARG C 242
GLU C   4
THR C   3
 None
 0.89A 3v4tA-5gnwC:
undetectable		 3v4tA-5gnwC:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gz4 SNAKE VENOM
PHOSPHODIESTERASE
(PDE)

(Naja atra) 		PF01033
(Somatomedin_B)
PF01223
(Endonuclease_NS)
PF01663
(Phosphodiest) 		3 ARG A  58
GLU A  57
THR A  56
 None
 0.82A 3v4tA-5gz4A:
undetectable		 3v4tA-5gz4A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB

(Mus musculus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		3 ARG A  51
GLU A 294
THR A 293
 None
None
FMT  A1007 (-3.5A)
 0.92A 3v4tA-5hjrA:
undetectable		 3v4tA-5hjrA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jlt MIDDLE TRANSCRIPTION
REGULATORY PROTEIN
MOTA

(Escherichia
virus T4) 		PF09158
(MotCF) 		3 ARG A 196
GLU A 111
THR A 107
 None
 0.80A 3v4tA-5jltA:
2.2		 3v4tA-5jltA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k0y EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT G
EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT I

(Homo sapiens;
Oryctolagus
cuniculus) 		PF12353
(eIF3g)
PF00400
(WD40) 		3 ARG T 326
GLU T 277
THR M 132
 None
 0.88A 3v4tA-5k0yT:
2.6		 3v4tA-5k0yT:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf7 BIFUNCTIONAL PROTEIN
PUTA

(Sinorhizobium
meliloti) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		3 ARG A 903
GLU A 910
THR A 927
 None
 0.91A 3v4tA-5kf7A:
0.2		 3v4tA-5kf7A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE DELTA
SUBUNIT
ACETOPHENONE
CARBOXYLASE GAMMA
SUBUNIT

(Aromatoleum
aromaticum;
Aromatoleum
aromaticum) 		PF02538
(Hydantoinase_B)
PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		3 ARG B 145
GLU A 450
THR A 449
 None
 0.81A 3v4tA-5l9wB:
undetectable		 3v4tA-5l9wB:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msc CARBOXYLIC ACID
REDUCTASE

(Nocardia
iowensis) 		PF00501
(AMP-binding) 		3 ARG A 209
GLU A 222
THR A 223
 None
 0.89A 3v4tA-5mscA:
undetectable		 3v4tA-5mscA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opj RHAMNOGALACTURONAN
LYASE

(Bacteroides
thetaiotaomicron) 		no annotation 3 ARG A  60
GLU A  82
THR A  79
 None
 0.88A 3v4tA-5opjA:
undetectable		 3v4tA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u0l N-SUCCINYLGLUTAMATE
5-SEMIALDEHYDE
DEHYDROGENASE

(Marinobacter
hydrocarbonoclasticus) 		PF00171
(Aldedh) 		3 ARG A 281
GLU A 102
THR A 101
 EDO  A 509 ( 4.9A)
None
None
 0.79A 3v4tA-5u0lA:
undetectable		 3v4tA-5u0lA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x8r 30S RIBOSOMAL
PROTEIN S6 ALPHA,
CHLOROPLASTIC

(Spinacia
oleracea) 		no annotation 3 ARG f 123
GLU f 122
THR f 119
 None
 0.88A 3v4tA-5x8rf:
undetectable		 3v4tA-5x8rf:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yw5 ADENINE
PHOSPHORIBOSYLTRANSF
ERASE

(Francisella
tularensis) 		no annotation 3 ARG A  63
GLU A  61
THR A  60
 None
 0.82A 3v4tA-5yw5A:
undetectable		 3v4tA-5yw5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		no annotation 3 ARG A 152
GLU A 574
THR A 572
 None
 0.80A 3v4tA-5ze4A:
undetectable		 3v4tA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c54 NUCLEOPROTEIN

(Zaire
ebolavirus) 		no annotation 3 ARG A 260
GLU A 259
THR A 258
 None
 0.82A 3v4tA-6c54A:
undetectable		 3v4tA-6c54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6czm -

(-) 		no annotation 3 ARG A 269
GLU A 359
THR A 361
 None
 0.69A 3v4tA-6czmA:
0.7		 3v4tA-6czmA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f1e INTERFERON GAMMA

(Paralichthys
olivaceus) 		no annotation 3 ARG A 181
GLU A  65
THR A  66
 None
 0.80A 3v4tA-6f1eA:
undetectable		 3v4tA-6f1eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fnz NEURONAL MIGRATION
PROTEIN DOUBLECORTIN

(Homo sapiens) 		no annotation 3 ARG A 267
GLU A 302
THR A 303
 None
 0.85A 3v4tA-6fnzA:
undetectable		 3v4tA-6fnzA:
undetectable