SIMILAR PATTERNS OF AMINO ACIDS FOR 3V3O_A_T1CA404_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e4o | MALTODEXTRINPHOSPHORYLASE (Escherichiacoli) |
PF00343(Phosphorylase) | 5 | THR A 452PHE A 778GLY A 776GLY A 642ASN A 661 | NoneNoneNonePLP A 999 (-3.4A)None | 1.22A | 3v3oA-1e4oA:undetectable | 3v3oA-1e4oA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lf9 | GLUCOAMYLASE (Thermoanaerobacteriumthermosaccharolyticum) |
PF00723(Glyco_hydro_15)PF09137(Glucodextran_N) | 5 | THR A 220ASN A 216GLY A 82ALA A 154GLY A 233 | None | 1.27A | 3v3oA-1lf9A:undetectable | 3v3oA-1lf9A:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o9j | ALDEHYDEDEHYDROGENASE,CYTOSOLIC 1 (Elephantulusedwardii) |
PF00171(Aldedh) | 5 | GLN A 292PHE A 295ASN A 297GLY A 293GLN A 382 | None | 1.06A | 3v3oA-1o9jA:undetectable | 3v3oA-1o9jA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pjm | IMPORTIN ALPHA-2SUBUNIT (Mus musculus) |
PF00514(Arm)PF16186(Arm_3) | 5 | ASN B 375HIS B 376ALA B 364GLY B 365ASN B 403 | None | 1.18A | 3v3oA-1pjmB:undetectable | 3v3oA-1pjmB:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1si8 | CATALASE (Enterococcusfaecalis) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | PHE A 111GLY A 126ALA A 60GLY A 59MET A 295 | NoneHEM A 501 (-3.8A)NoneNoneNone | 0.99A | 3v3oA-1si8A:undetectable | 3v3oA-1si8A:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1si8 | CATALASE (Enterococcusfaecalis) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | THR A 94PHE A 111GLY A 126MET A 295GLN A 219 | NoneNoneHEM A 501 (-3.8A)NoneNone | 1.24A | 3v3oA-1si8A:undetectable | 3v3oA-1si8A:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sy7 | CATALASE 1 (Neurosporacrassa) |
PF00199(Catalase)PF01965(DJ-1_PfpI)PF06628(Catalase-rel) | 5 | PHE A 149GLY A 164ALA A 98GLY A 97MET A 337 | NoneHDD A1880 ( 3.9A)NoneNoneNone | 0.95A | 3v3oA-1sy7A:undetectable | 3v3oA-1sy7A:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ulv | GLUCODEXTRANASE (Arthrobacterglobiformis) |
PF00723(Glyco_hydro_15)PF09136(Glucodextran_B)PF09137(Glucodextran_N)PF09985(Glucodextran_C) | 5 | THR A 675GLN A 336ALA A 664GLY A 666MET A 616 | None | 1.19A | 3v3oA-1ulvA:undetectable | 3v3oA-1ulvA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w6j | LANOSTEROL SYNTHASE (Homo sapiens) |
PF13243(SQHop_cyclase_C)PF13249(SQHop_cyclase_N) | 5 | GLN A 135ARG A 177ASN A 178GLY A 140GLY A 167 | None | 1.18A | 3v3oA-1w6jA:undetectable | 3v3oA-1w6jA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w6s | METHANOLDEHYDROGENASESUBUNIT 1 (Methylobacteriumextorquens) |
PF01011(PQQ)PF13360(PQQ_2) | 5 | ASN A 394HIS A 393GLY A 410ALA A 57GLY A 56 | PQQ A1596 (-3.6A)NoneNoneNoneNone | 1.16A | 3v3oA-1w6sA:undetectable | 3v3oA-1w6sA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ya0 | SMG-7 TRANSCRIPTVARIANT 2 (Homo sapiens) |
PF10373(EST1_DNA_bind)PF10374(EST1) | 5 | THR A 298GLY A 340ALA A 358ASN A 357GLN A 456 | None | 1.16A | 3v3oA-1ya0A:undetectable | 3v3oA-1ya0A:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yzy | HYPOTHETICAL PROTEINHI1011 (Haemophilusinfluenzae) |
PF07005(DUF1537)PF17042(DUF1357_C) | 5 | THR A 217GLY A 2ALA A 224GLY A 221ASN A 21 | None | 1.11A | 3v3oA-1yzyA:undetectable | 3v3oA-1yzyA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zcc | GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE (Agrobacteriumfabrum) |
PF03009(GDPD) | 5 | PHE A 84GLY A 78ALA A 10GLY A 9GLN A 27 | None | 1.02A | 3v3oA-1zccA:undetectable | 3v3oA-1zccA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bbv | PROTEIN (BLACKBEETLE VIRUS CAPSIDPROTEIN) (Black beetlevirus) |
PF01829(Peptidase_A6) | 5 | THR A 189ASN A 230ALA A 360GLY A 238ASN A 363 | None | 1.22A | 3v3oA-2bbvA:undetectable | 3v3oA-2bbvA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfb | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Synechococcuselongatus) |
PF00202(Aminotran_3) | 5 | THR A 248GLN A 237PHE A 229GLY A 235ALA A 82 | None | 1.22A | 3v3oA-2cfbA:undetectable | 3v3oA-2cfbA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0v | METHANOLDEHYDROGENASE LARGESUBUNIT (Hyphomicrobiumdenitrificans) |
PF01011(PQQ)PF13360(PQQ_2) | 5 | ASN A 108GLY A 539ALA A 176GLY A 175ASN A 261 | NonePQQ A 601 (-3.4A)PQQ A 601 (-3.3A)PQQ A 601 (-3.2A) CA A 775 (-2.8A) | 1.20A | 3v3oA-2d0vA:undetectable | 3v3oA-2d0vA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0v | METHANOLDEHYDROGENASE LARGESUBUNIT (Hyphomicrobiumdenitrificans) |
PF01011(PQQ)PF13360(PQQ_2) | 5 | ASN A 394HIS A 393GLY A 410ALA A 57GLY A 56 | PQQ A 601 (-3.5A)NoneNoneNoneNone | 1.18A | 3v3oA-2d0vA:undetectable | 3v3oA-2d0vA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2egg | SHIKIMATE5-DEHYDROGENASE (Geobacilluskaustophilus) |
PF01488(Shikimate_DH)PF08501(Shikimate_dh_N) | 5 | THR A 122ASN A 108GLY A 152GLY A 264ASN A 261 | None | 1.12A | 3v3oA-2eggA:undetectable | 3v3oA-2eggA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fmt | METHIONYL-TRNA FMETFORMYLTRANSFERASE (Escherichiacoli) |
PF00551(Formyl_trans_N)PF02911(Formyl_trans_C) | 5 | THR A 159ARG A 228GLY A 165ALA A 129GLY A 130 | None | 1.00A | 3v3oA-2fmtA:4.7 | 3v3oA-2fmtA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i1j | MOESIN (Spodopterafrugiperda) |
PF00373(FERM_M)PF00769(ERM)PF09379(FERM_N)PF09380(FERM_C) | 5 | ASN A 138GLY A 135ALA A 148GLY A 145ASN A 149 | None | 1.25A | 3v3oA-2i1jA:undetectable | 3v3oA-2i1jA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ibj | CYTOCHROME B5 (Musca domestica) |
PF00173(Cyt-b5) | 5 | THR A 8GLY A 77ALA A 50GLY A 51ASN A 21 | None | 1.21A | 3v3oA-2ibjA:undetectable | 3v3oA-2ibjA:11.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j2m | CATALASE (Exiguobacteriumoxidotolerans) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | PHE A 113GLY A 128ALA A 62GLY A 61MET A 297 | NoneHEM A 501 (-3.7A)NoneNoneNone | 0.98A | 3v3oA-2j2mA:undetectable | 3v3oA-2j2mA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ri6 | 2-HYDROXY-6-OXO-6-PHENYLHEXA-2,4-DIENOATE HYDROLASE (Paraburkholderiaxenovorans) |
PF12697(Abhydrolase_6) | 5 | THR A 219ASN A 251ALA A 112GLY A 138ASN A 111 | NoneNoneMLI A 2 (-3.2A)NoneNone | 0.91A | 3v3oA-2ri6A:undetectable | 3v3oA-2ri6A:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ver | AFIMBRIAL ADHESINAFA-IIIARCINOEMBRYONICANTIGEN-RELATED CELLADHESION MOLECULE 5 (Escherichiacoli;Homo sapiens) |
PF04619(Adhesin_Dr)PF07686(V-set) | 5 | THR A 95GLY A 8ALA N 55GLY N 47GLN N 53 | MTN N1111 ( 4.7A)NoneNoneNoneNone | 1.25A | 3v3oA-2verA:undetectable | 3v3oA-2verA:15.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vqr | PUTATIVE SULFATASE (Rhizobiumleguminosarum) |
PF00884(Sulfatase)PF16347(DUF4976) | 5 | PHE A 47GLY A 366ALA A 360GLY A 361ASN A 357 | None | 1.10A | 3v3oA-2vqrA:undetectable | 3v3oA-2vqrA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xf2 | CATALASE (Penicilliumjanthinellum) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | PHE A 121GLY A 136ALA A 70GLY A 69MET A 309 | NoneHDD A 690 (-3.9A)NoneNoneNone | 1.01A | 3v3oA-2xf2A:4.2 | 3v3oA-2xf2A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zoo | PROBABLE NITRITEREDUCTASE (Pseudoalteromonashaloplanktis) |
PF00034(Cytochrom_C)PF00394(Cu-oxidase)PF07732(Cu-oxidase_3) | 5 | GLN A 436ASN A 416ALA A 428GLY A 429ASN A 375 | None | 1.23A | 3v3oA-2zooA:undetectable | 3v3oA-2zooA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b7m | CELLULASE (Rhodothermusmarinus) |
PF01670(Glyco_hydro_12) | 5 | ASN A 120GLY A 123ALA A 204GLY A 205GLN A 32 | None | 1.19A | 3v3oA-3b7mA:undetectable | 3v3oA-3b7mA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bpt | 3-HYDROXYISOBUTYRYL-COA HYDROLASE (Homo sapiens) |
PF16113(ECH_2) | 5 | GLN A 313PHE A 183GLY A 181ALA A 166GLY A 199 | None | 1.19A | 3v3oA-3bptA:undetectable | 3v3oA-3bptA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bw2 | 2-NITROPROPANEDIOXYGENASE (Streptomycesansochromogenes) |
PF03060(NMO) | 5 | ARG A 281PHE A 282GLY A 287ALA A 93GLY A 91 | None | 1.22A | 3v3oA-3bw2A:undetectable | 3v3oA-3bw2A:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c4a | PROBABLE TRYPTOPHANHYDROXYLASE VIOD (Chromobacteriumviolaceum) |
no annotation | 5 | HIS A 102GLY A 99ALA A 11GLY A 12GLN A 290 | NoneNoneFAD A 401 (-3.4A)NoneNone | 0.88A | 3v3oA-3c4aA:26.7 | 3v3oA-3c4aA:24.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cem | GLYCOGENPHOSPHORYLASE, LIVERFORM (Homo sapiens) |
PF00343(Phosphorylase) | 5 | THR A 487PHE A 811GLY A 809GLY A 677ASN A 696 | NoneNoneNonePLP A 832 (-3.8A)None | 1.27A | 3v3oA-3cemA:2.1 | 3v3oA-3cemA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dlj | BETA-ALA-HISDIPEPTIDASE (Homo sapiens) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ASN A 140GLY A 445GLY A 134ASN A 455GLN A 454 | ZN A2002 ( 4.7A)NoneNoneNoneNone | 1.25A | 3v3oA-3dljA:undetectable | 3v3oA-3dljA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dqq | PUTATIVE TRNASYNTHASE (Salmonellaenterica) |
PF07005(DUF1537)PF17042(DUF1357_C) | 5 | GLN A 161GLY A 96ALA A 196GLY A 167GLN A 189 | None | 1.21A | 3v3oA-3dqqA:undetectable | 3v3oA-3dqqA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g3s | GCN5-RELATEDN-ACETYLTRANSFERASE (Streptococcussuis) |
PF12746(GNAT_acetyltran) | 5 | THR A 135ASN A 131ALA A 174GLY A 173GLN A 206 | None | 1.02A | 3v3oA-3g3sA:undetectable | 3v3oA-3g3sA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3grh | ACYL-COA THIOESTERHYDROLASE YBGC (Escherichiacoli) |
PF01095(Pectinesterase) | 5 | ARG A 14PHE A 340GLY A 311ALA A 335GLY A 388 | None | 1.27A | 3v3oA-3grhA:undetectable | 3v3oA-3grhA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3icv | LIPASE B (Moesziomycesantarcticus) |
no annotation | 5 | THR A 77GLN A 140GLY A 141GLY A 53ASN A 119 | None | 1.26A | 3v3oA-3icvA:undetectable | 3v3oA-3icvA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9e | VP5 (Bluetonguevirus) |
PF00901(Orbi_VP5) | 5 | THR D 163ASN D 159ALA D 251GLY D 249ASN D 108 | None | 1.18A | 3v3oA-3j9eD:undetectable | 3v3oA-3j9eD:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k2q | PYROPHOSPHATE-DEPENDENTPHOSPHOFRUCTOKINASE (Marinobacterhydrocarbonoclasticus) |
PF00365(PFK) | 5 | THR A 71GLN A 27ASN A 19GLY A 24ALA A 308 | None | 1.27A | 3v3oA-3k2qA:undetectable | 3v3oA-3k2qA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o31 | THERMONICOTIANAMINESYNTHASE (Methanothermobacterthermautotrophicus) |
PF03059(NAS) | 5 | THR A 182PHE A 205ASN A 207ALA A 195GLY A 130 | NoneNoneNone3O3 A 1 (-3.5A)None | 1.18A | 3v3oA-3o31A:4.4 | 3v3oA-3o31A:20.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p9u | TETX2 PROTEIN (Bacteroidesthetaiotaomicron) |
PF01494(FAD_binding_3) | 9 | THR A 59GLN A 192ARG A 213ASN A 226HIS A 234GLY A 236ALA A 320GLY A 321ASN A 371 | SO4 A 1 (-3.7A)FAD A 401 (-3.4A)SO4 A 1 (-4.5A)SO4 A 1 (-4.5A)SO4 A 1 ( 4.6A)NoneNoneNoneNone | 0.81A | 3v3oA-3p9uA:57.5 | 3v3oA-3p9uA:99.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p9u | TETX2 PROTEIN (Bacteroidesthetaiotaomicron) |
PF01494(FAD_binding_3) | 9 | THR A 59GLN A 192ARG A 213ASN A 226HIS A 234GLY A 236ALA A 320GLY A 321MET A 375 | SO4 A 1 (-3.7A)FAD A 401 (-3.4A)SO4 A 1 (-4.5A)SO4 A 1 (-4.5A)SO4 A 1 ( 4.6A)NoneNoneNoneNone | 0.75A | 3v3oA-3p9uA:57.5 | 3v3oA-3p9uA:99.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qdf | 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATEISOMERASE (Mycobacteriummarinum) |
PF01557(FAA_hydrolase)PF10370(DUF2437) | 5 | PHE A 116ASN A 257GLY A 118ALA A 195GLY A 194 | None | 1.05A | 3v3oA-3qdfA:undetectable | 3v3oA-3qdfA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qfk | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF00149(Metallophos)PF02872(5_nucleotid_C) | 5 | GLN A 59HIS A 13GLY A 60ALA A 352ASN A 367 | None ZN A 512 (-3.5A)NoneNoneNone | 1.26A | 3v3oA-3qfkA:undetectable | 3v3oA-3qfkA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qk8 | ENOYL-COA HYDRATASEECHA15 (Mycobacteriummarinum) |
PF00378(ECH_1) | 5 | THR A 141PHE A 239GLY A 241ALA A 117GLY A 116 | NoneNoneNoneUNL A 291 ( 3.3A)None | 1.27A | 3v3oA-3qk8A:undetectable | 3v3oA-3qk8A:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r67 | PUTATIVE GLYCOSIDASE (Bacteroidesthetaiotaomicron) |
PF04041(Glyco_hydro_130) | 5 | ARG A 258GLY A 294ALA A 305GLY A 306ASN A 285 | NoneEDO A 389 ( 3.7A)NoneNoneNone | 1.22A | 3v3oA-3r67A:undetectable | 3v3oA-3r67A:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rj8 | CARBOHYDRATE OXIDASE (Microdochiumnivale) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | PHE A 141HIS A 143GLY A 144ALA A 110GLY A 109 | NoneFAD A 501 (-4.8A)NoneNoneNone | 1.22A | 3v3oA-3rj8A:undetectable | 3v3oA-3rj8A:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rrw | THYLAKOID LUMENAL 29KDA PROTEIN,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00141(peroxidase) | 5 | THR A 240PHE A 149GLY A 150ALA A 105GLY A 106 | NoneNoneGOL A 273 ( 4.2A)NoneNone | 1.15A | 3v3oA-3rrwA:undetectable | 3v3oA-3rrwA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3swx | PROBABLE ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteroidesabscessus) |
PF00378(ECH_1) | 5 | GLY A 94ALA A 218GLY A 222ASN A 214GLN A 229 | None | 1.20A | 3v3oA-3swxA:undetectable | 3v3oA-3swxA:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tav | METHIONINEAMINOPEPTIDASE (Mycobacteroidesabscessus) |
PF00557(Peptidase_M24) | 5 | HIS A 184GLY A 185ALA A 146GLY A 143ASN A 151 | MG A 266 (-3.4A)NoneNoneNoneNone | 1.21A | 3v3oA-3tavA:undetectable | 3v3oA-3tavA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsy | FUSION PROTEIN4-COUMARATE--COALIGASE 1,RESVERATROL SYNTHASE (Arabidopsisthaliana;Vitis vinifera) |
PF00195(Chal_sti_synt_N)PF00501(AMP-binding)PF02797(Chal_sti_synt_C)PF13193(AMP-binding_C) | 5 | THR A 851PHE A 785GLY A 671ALA A 800GLY A 798 | None | 1.27A | 3v3oA-3tsyA:undetectable | 3v3oA-3tsyA:18.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wel | ALPHA-GLUCOSIDASE (Beta vulgaris) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16863(NtCtMGAM_N) | 5 | THR A 562GLY A 244ALA A 596GLY A 595ASN A 569 | None | 1.19A | 3v3oA-3welA:undetectable | 3v3oA-3welA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wh9 | ENDO-BETA-1,4-MANNANASE (Aspergillusniger) |
PF00150(Cellulase) | 5 | THR A 336GLN A 291GLY A 288ALA A 345GLY A 343 | None | 1.16A | 3v3oA-3wh9A:undetectable | 3v3oA-3wh9A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zq4 | RIBONUCLEASE J 1 (Bacillussubtilis) |
PF00753(Lactamase_B)PF07521(RMMBL) | 5 | PHE A 137HIS A 161GLY A 149GLY A 69ASN A 120 | None | 1.17A | 3v3oA-3zq4A:undetectable | 3v3oA-3zq4A:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aah | METHANOLDEHYDROGENASE (Methylophilusmethylotrophus) |
PF13360(PQQ_2) | 5 | ASN A 387HIS A 386GLY A 403ALA A 57GLY A 56 | PQQ A 701 (-3.5A)NoneNoneNoneNone | 1.15A | 3v3oA-4aahA:undetectable | 3v3oA-4aahA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aj9 | CATALASE-3 (Neurosporacrassa) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | PHE A 159GLY A 174ALA A 108GLY A 107MET A 347 | NoneHEM A1715 (-3.8A)NoneNoneNone | 0.99A | 3v3oA-4aj9A:4.5 | 3v3oA-4aj9A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bkw | ZINC FINGER FYVEDOMAIN-CONTAININGPROTEIN 9 (Homo sapiens) |
PF11979(DUF3480) | 5 | THR A1312ARG A1310GLY A 969ALA A1008GLY A1009 | None | 1.24A | 3v3oA-4bkwA:undetectable | 3v3oA-4bkwA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cab | CATALASE (Deinococcusradiodurans) |
PF00199(Catalase)PF06628(Catalase-rel) | 6 | THR A 126PHE A 143GLY A 158ALA A 87GLY A 86MET A 327 | NoneNoneHEM A 537 (-4.0A)NoneNoneNone | 1.41A | 3v3oA-4cabA:undetectable | 3v3oA-4cabA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cx9 | CYTOCHROME C, CLASSII (Shewanellafrigidimarina) |
PF01322(Cytochrom_C_2) | 5 | PHE A 23ASN A 47GLY A 24ALA A 110ASN A 113 | HEC A1129 ( 4.0A)NoneNoneNoneNone | 1.22A | 3v3oA-4cx9A:undetectable | 3v3oA-4cx9A:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d70 | SORTASE FAMILYPROTEIN (Clostridiumperfringens) |
PF04203(Sortase) | 5 | THR A 167ASN A 103GLY A 99ALA A 77GLY A 90 | None | 0.95A | 3v3oA-4d70A:undetectable | 3v3oA-4d70A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ff5 | GLYCOSYL HYDROLASE25 (Streptococcuspneumoniae) |
PF01183(Glyco_hydro_25) | 5 | THR A 235GLY A 160ALA A 55GLY A 54GLN A 89 | None | 1.19A | 3v3oA-4ff5A:undetectable | 3v3oA-4ff5A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fff | LEVANFRUCTOTRANSFERASE (Paenarthrobacterureafaciens) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 5 | THR A 420ARG A 421GLY A 497GLY A 437GLN A 488 | None | 1.13A | 3v3oA-4fffA:undetectable | 3v3oA-4fffA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g2a | HYPOTHETICAL PROTEIN (Legionellapneumophila) |
PF13308(YARHG)PF14415(DUF4424) | 5 | GLY A 35ALA A 108GLY A 109ASN A 61GLN A 66 | NoneSO4 A 411 (-3.5A)SO4 A 411 (-3.5A)NoneNone | 1.19A | 3v3oA-4g2aA:undetectable | 3v3oA-4g2aA:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gf8 | PEPTIDE ABCTRANSPORTER,PERIPLASMICPEPTIDE-BINDINGPROTEIN (Vibrio cholerae) |
PF00496(SBP_bac_5) | 5 | THR A 245ASN A 293ALA A 413GLY A 412ASN A 46 | None | 1.17A | 3v3oA-4gf8A:undetectable | 3v3oA-4gf8A:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ip4 | MANDELATERACEMASE/MUCONATELACTONIZINGENZYME-LIKE PROTEIN (Ruegeria sp.TM1040) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | THR A 53GLY A 112ALA A 350GLY A 351MET A 362 | NoneNoneNoneGOL A 501 (-3.5A)None | 1.24A | 3v3oA-4ip4A:undetectable | 3v3oA-4ip4A:25.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4izd | ENOYL-COAHYDRATASE/ISOMERASEFAMILY PROTEIN (Ruegeriapomeroyi) |
PF00378(ECH_1) | 5 | THR A 135GLY A 119ALA A 63GLY A 64ASN A 27 | None | 1.13A | 3v3oA-4izdA:undetectable | 3v3oA-4izdA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcm | CYCLODEXTRINGLUCANOTRANSFERASE ([Bacillus]clarkii) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 5 | PHE A 338GLY A 335GLY A 344MET A 296GLN A 301 | None | 1.19A | 3v3oA-4jcmA:undetectable | 3v3oA-4jcmA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lsw | D-2-HYDROXYACIDDEHYDROGENSASEPROTEIN (Ketogulonicigeniumvulgare) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | PHE A 202ASN A 231GLY A 108GLY A 227MET A 169 | None | 1.17A | 3v3oA-4lswA:3.4 | 3v3oA-4lswA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mad | BETA-GALACTOSIDASE (Bacilluscirculans) |
PF01301(Glyco_hydro_35) | 5 | GLN A 542ARG A 28ALA A 285GLY A 284ASN A 286 | NoneNoneNoneNonePG0 A 900 ( 4.7A) | 1.20A | 3v3oA-4madA:undetectable | 3v3oA-4madA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oe5 | DELTA-1-PYRROLINE-5-CARBOXYLATEDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF00171(Aldedh) | 5 | THR A 237ASN A 211GLY A 266GLY A 216ASN A 283 | None | 1.05A | 3v3oA-4oe5A:3.1 | 3v3oA-4oe5A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ojz | PUTATIVE ALGINATELYASE (Saccharophagusdegradans) |
PF05426(Alginate_lyase)PF07940(Hepar_II_III) | 5 | PHE A 416ASN A 420GLY A 414GLY A 577GLN A 472 | None | 1.17A | 3v3oA-4ojzA:undetectable | 3v3oA-4ojzA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4onz | PUTATIVE GLYCOSIDEHYDROLASE (Bacteroidesovatus) |
PF04041(Glyco_hydro_130) | 5 | ARG A 259GLY A 294ALA A 305GLY A 306ASN A 286 | None | 1.20A | 3v3oA-4onzA:undetectable | 3v3oA-4onzA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pys | BETA-N-ACETYLHEXOSAMINIDASE (Bacteroidesfragilis) |
PF00728(Glyco_hydro_20)PF02838(Glyco_hydro_20b) | 5 | ASN A 269GLY A 240ALA A 201GLY A 200GLN A 209 | None | 1.20A | 3v3oA-4pysA:undetectable | 3v3oA-4pysA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qor | CATALASE (Bacilluspumilus) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | PHE A 114GLY A 129ALA A 63GLY A 62MET A 298 | NoneHEM A 501 ( 3.8A)NoneNoneNone | 1.01A | 3v3oA-4qorA:undetectable | 3v3oA-4qorA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qvr | UNCHARACTERIZEDHYPOTHETICAL PROTEINFTT_1539C (Francisellatularensis) |
no annotation | 5 | GLN A 311ARG A 295GLY A 310ALA A 121GLN A 126 | None | 1.10A | 3v3oA-4qvrA:undetectable | 3v3oA-4qvrA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tqo | METHANOLDEHYDROGENASEPROTEIN, LARGESUBUNIT (Methylococcuscapsulatus) |
no annotation | 5 | ASN B 136GLY B 560ALA B 204GLY B 203ASN B 289 | NonePQQ B 702 (-3.6A)PQQ B 702 (-3.0A)PQQ B 702 (-3.1A) CA B 701 ( 2.8A) | 1.21A | 3v3oA-4tqoB:undetectable | 3v3oA-4tqoB:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4urs | DIGUANYLATE CYCLASE (Thermotogamaritima) |
PF00990(GGDEF) | 5 | GLY A 167ALA A 128GLY A 129ASN A 210MET A 234 | GLY A 167 ( 0.0A)ALA A 128 ( 0.0A)GLY A 129 ( 0.0A)ASN A 210 ( 0.6A)MET A 234 ( 0.0A) | 1.23A | 3v3oA-4ursA:undetectable | 3v3oA-4ursA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xn3 | TAIL SPIKE PROTEIN (Salmonellavirus HK620) |
no annotation | 5 | ARG A 505GLY A 529ALA A 474GLY A 473ASN A 476 | None | 1.13A | 3v3oA-4xn3A:undetectable | 3v3oA-4xn3A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xsr | ALR3699 PROTEIN (Nostoc sp. PCC7120) |
no annotation | 5 | PHE B 362GLY B 175ALA B 312GLY B 311MET B 298 | None | 1.24A | 3v3oA-4xsrB:3.7 | 3v3oA-4xsrB:25.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zv7 | LIPASE B (Moesziomycesantarcticus) |
no annotation | 5 | THR A 43GLN A 106GLY A 107GLY A 19ASN A 85 | None | 1.27A | 3v3oA-4zv7A:undetectable | 3v3oA-4zv7A:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8q | PUTATIVE RETAININGB-GLYCOSIDASE (Saccharophagusdegradans) |
PF00150(Cellulase) | 5 | THR A 328GLN A 351PHE A 332ASN A 72GLY A 98 | None | 1.25A | 3v3oA-5a8qA:undetectable | 3v3oA-5a8qA:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8q | PUTATIVE RETAININGB-GLYCOSIDASE (Saccharophagusdegradans) |
PF00150(Cellulase) | 5 | THR A 328PHE A 332ASN A 72ALA A 94ASN A 95 | None | 1.19A | 3v3oA-5a8qA:undetectable | 3v3oA-5a8qA:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8q | PUTATIVE RETAININGB-GLYCOSIDASE (Saccharophagusdegradans) |
PF00150(Cellulase) | 5 | THR A 328PHE A 332ASN A 72GLY A 98ASN A 96 | None | 1.20A | 3v3oA-5a8qA:undetectable | 3v3oA-5a8qA:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b47 | 2-OXOACID--FERREDOXIN OXIDOREDUCTASEBETA SUBUNIT (Sulfurisphaeratokodaii) |
PF02775(TPP_enzyme_C)PF12367(PFO_beta_C) | 5 | PHE B 101HIS B 103GLY B 99ALA B 154ASN B 151 | None | 1.04A | 3v3oA-5b47B:undetectable | 3v3oA-5b47B:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cer | BD0816 (Bdellovibriobacteriovorus) |
PF02113(Peptidase_S13) | 5 | PHE A 334ASN A 333GLY A 336ALA A 386GLY A 384 | None | 1.18A | 3v3oA-5cerA:undetectable | 3v3oA-5cerA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dgq | PUTATIVEENDOGLUCANASE-RELATED PROTEIN (Photobacteriumprofundum) |
PF00759(Glyco_hydro_9) | 5 | PHE A 99HIS A 104ALA A 562GLY A 561ASN A 168 | None | 1.25A | 3v3oA-5dgqA:undetectable | 3v3oA-5dgqA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7s | GLYCOSIDE HYDROLASEFAMILY 31 (Trueperellapyogenes) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 5 | THR A 274PHE A 280ASN A 278ALA A 550GLY A 551 | None | 1.02A | 3v3oA-5f7sA:undetectable | 3v3oA-5f7sA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gka | CAPSID PROTEIN VP0 (Aichivirus A) |
PF00073(Rhv) | 5 | GLN B 334ARG B 288ASN B 290GLY B 190ALA B 283 | None | 1.23A | 3v3oA-5gkaB:undetectable | 3v3oA-5gkaB:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hdm | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE1, CHLOROPLASTIC (Arabidopsisthaliana) |
PF00202(Aminotran_3) | 5 | THR A 271GLN A 260PHE A 252GLY A 258ALA A 105 | None | 1.26A | 3v3oA-5hdmA:undetectable | 3v3oA-5hdmA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mp4 | PROTOPLAST SECRETEDPROTEIN 2 (Saccharomycescerevisiae) |
PF03358(FMN_red) | 5 | THR A 166GLN A 187ALA A 122GLY A 119ASN A 126 | None | 1.00A | 3v3oA-5mp4A:3.6 | 3v3oA-5mp4A:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n8p | S-LAYER PROTEIN (Caulobactervibrioides) |
PF00353(HemolysinCabind) | 5 | ASN A 788GLY A 739ALA A 782GLY A 783GLN A 806 | NoneNoneNone CA A9009 ( 3.7A)None | 0.86A | 3v3oA-5n8pA:undetectable | 3v3oA-5n8pA:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n97 | S-LAYER PROTEIN RSAA (Caulobactervibrioides) |
PF00353(HemolysinCabind) | 5 | ASN A 788GLY A 739ALA A 782GLY A 783GLN A 806 | NoneNoneNone CA A9009 ( 3.7A)None | 0.87A | 3v3oA-5n97A:undetectable | 3v3oA-5n97A:16.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nvm | EUKARYOTICTRANSLATIONINITIATION FACTOR 4ETYPE 2 (Homo sapiens) |
PF01652(IF4E) | 5 | GLN A 84ASN A 59GLY A 86ALA A 169GLY A 168 | None | 1.17A | 3v3oA-5nvmA:2.3 | 3v3oA-5nvmA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wpw | 11S GLOBULIN ISOFORM1 (Cocos nucifera) |
no annotation | 5 | THR A 58GLN A 204ARG A 60GLY A 252ASN A 170 | None | 1.25A | 3v3oA-5wpwA:undetectable | 3v3oA-5wpwA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgv | PYRE3 (Streptomycesrugosporus) |
no annotation | 5 | GLN A 56ARG A 322ASN A 297GLY A 440GLY A 289 | None | 1.26A | 3v3oA-5xgvA:27.0 | 3v3oA-5xgvA:14.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xm3 | GLUCOSEDEHYDROGENASE (Methylophagaaminisulfidivorans) |
no annotation | 5 | ASN A 264GLY A 233ALA A 207GLY A 210ASN A 292 | NoneNonePQQ A 701 (-3.0A)None MG A 702 ( 3.0A) | 1.16A | 3v3oA-5xm3A:undetectable | 3v3oA-5xm3A:11.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6az1 | RIBOSOMAL PROTEINS8E (Leishmaniadonovani) |
no annotation | 5 | THR K 95ASN K 35GLY K 193ALA K 40GLY K 39 | NoneNone G 1 375 ( 3.8A)NoneNone | 1.06A | 3v3oA-6az1K:undetectable | 3v3oA-6az1K:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bzc | GLUCOSE-6-PHOSPHATEISOMERASE (Elizabethkingiaanophelis) |
no annotation | 5 | THR A 466GLN A 426PHE A 387HIS A 392GLN A 349 | GOL A 605 ( 4.6A)NoneNoneNoneNone | 1.24A | 3v3oA-6bzcA:undetectable | 3v3oA-6bzcA:14.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d3i | - (-) |
no annotation | 5 | THR A 115ASN A 218HIS A 111GLY A 107GLY A 195 | NoneNone CO A 301 ( 3.2A)AKG A 302 (-3.1A)None | 1.25A | 3v3oA-6d3iA:undetectable | 3v3oA-6d3iA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fea | NITROGENASE PROTEINALPHA CHAIN (Azotobactervinelandii) |
no annotation | 5 | ASN A 184HIS A 180GLY A 53GLY A 237ASN A 93 | NoneD6N A 502 (-4.6A)NoneNoneNone | 1.27A | 3v3oA-6feaA:undetectable | 3v3oA-6feaA:17.87 |